Overview

ID MAG01625
Name HFD1_bin.38
Sample SMP0043
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Pseudomonadales
Family Azotimanducaceae
Genus DATJGR01
Species
Assembly information
Completeness (%) 75.82
Contamination (%) 2.64
GC content (%) 64.0
N50 (bp) 4,646
Genome size (bp) 3,395,991

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3602

Gene name Description KEGG GOs EC E-value Score Sequence
HFD1_k127_1006077_0 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 394.0
HFD1_k127_1006077_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002446 273.0
HFD1_k127_1006077_2 thiolester hydrolase activity - - - 0.00000000000000000000000000000001326 137.0
HFD1_k127_1006077_3 Belongs to the peptidase M48B family K03799 - - 0.000000000000000002733 85.0
HFD1_k127_1008403_0 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000036 276.0
HFD1_k127_1008403_1 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.0000000000000000000000000000000000000000000000000000000008351 215.0
HFD1_k127_1008403_2 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000003428 153.0
HFD1_k127_1008403_3 response to cobalt ion - - - 0.00000000000000000000000000002812 124.0
HFD1_k127_1008403_4 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000003396 124.0
HFD1_k127_1008403_5 Putative zinc-finger K03088 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000002883 107.0
HFD1_k127_1008403_7 Transmembrane secretion effector - - - 0.0000000001248 69.0
HFD1_k127_1013768_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 593.0
HFD1_k127_1013768_1 rod shape-determining protein MreB K03569 GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005886,GO:0007049,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0032505,GO:0042802,GO:0043093,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051782,GO:0051983,GO:0065007,GO:0065008,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 568.0
HFD1_k127_1013768_2 Involved in the processing of the 5'end of 16S rRNA K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 546.0
HFD1_k127_1013768_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 516.0
HFD1_k127_1013768_4 Involved in formation and maintenance of cell shape K03570 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0043621,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944,GO:0071963 - 0.000000000000000000000000000000000000000000000000000000000000000000000003713 253.0
HFD1_k127_1013768_5 maF-like protein K06287 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429 - 0.0000000000000000000000000000000000000000000000000000000003799 207.0
HFD1_k127_1013768_6 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.000000000000000000000000000005274 127.0
HFD1_k127_1013768_7 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000001299 117.0
HFD1_k127_1019539_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008033,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016740,GO:0016765,GO:0019222,GO:0031323,GO:0031326,GO:0032268,GO:0033554,GO:0034248,GO:0034470,GO:0034605,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043555,GO:0044237,GO:0044238,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0051716,GO:0052381,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990497,GO:2000112,GO:2000765 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 321.0
HFD1_k127_1019539_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001791 268.0
HFD1_k127_1019539_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000002791 222.0
HFD1_k127_1019539_3 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000001568 143.0
HFD1_k127_1025136_0 Dehydrogenase E1 component K00164 GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2 0.0 1355.0
HFD1_k127_1025136_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 2.3.1.61 0.0000000000000000000000000000000006392 144.0
HFD1_k127_1032208_0 Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006136 567.0
HFD1_k127_1032208_1 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.000000000000000000000000000000000000000000000000000000000002648 212.0
HFD1_k127_1032208_2 - - - - 0.000002346 54.0
HFD1_k127_1034374_0 COG4166 ABC-type oligopeptide transport system, periplasmic component K15580 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006857,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0015833,GO:0030288,GO:0030313,GO:0031975,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042939,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 561.0
HFD1_k127_1034374_1 COG0714 MoxR-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 456.0
HFD1_k127_1034374_10 Could be a S-adenosyl-L-methionine-dependent methyltransferase K17462 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - 0.0000000000004003 79.0
HFD1_k127_1034374_2 containing von Willebrand factor type A (VWA) domain K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 463.0
HFD1_k127_1034374_3 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K15583,K16202 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005822 435.0
HFD1_k127_1034374_4 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K15581 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 412.0
HFD1_k127_1034374_5 Thioesterase-like superfamily K10805 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 380.0
HFD1_k127_1034374_6 Binding-protein-dependent transport system inner membrane component K15582 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 384.0
HFD1_k127_1034374_7 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 343.0
HFD1_k127_1034374_8 penicillin-binding protein K05367 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000005264 243.0
HFD1_k127_1034374_9 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.0000000000000000000001169 106.0
HFD1_k127_1043735_0 Carboxyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 506.0
HFD1_k127_1043735_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000008653 144.0
HFD1_k127_1057399_0 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000008184 233.0
HFD1_k127_1057399_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000004983 227.0
HFD1_k127_1057399_2 Phytanoyl-CoA dioxygenase (PhyH) K10674 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016706,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.14.11.55 0.0000000000000000000000000000000006554 144.0
HFD1_k127_1057399_3 helix_turn_helix, arabinose operon control protein - - - 0.0000007014 52.0
HFD1_k127_1067436_0 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000003918 222.0
HFD1_k127_1067436_1 dehydratase - - - 0.000000000000000000000000000000000008713 138.0
HFD1_k127_1067436_2 Protein involved in outer membrane biogenesis - - - 0.000003942 55.0
HFD1_k127_107130_0 pfam abc K01990,K13926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 549.0
HFD1_k127_107130_1 Biotin-lipoyl like K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 345.0
HFD1_k127_107130_2 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001177 283.0
HFD1_k127_107130_3 Transcriptional regulator - GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031333,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043254,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2000144,GO:2001141 - 0.000000000000000000000000000000000000000000000000003479 189.0
HFD1_k127_1072388_0 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 345.0
HFD1_k127_1072388_1 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000739 313.0
HFD1_k127_1072388_2 PFAM ring hydroxylating dioxygenase, alpha subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 301.0
HFD1_k127_1072388_3 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008671 295.0
HFD1_k127_1072388_4 Glutathione S-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004674 269.0
HFD1_k127_1072388_5 transcriptional regulator - - - 0.000000000000000204 89.0
HFD1_k127_1072777_0 glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 387.0
HFD1_k127_1072777_1 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887 - 0.0000000000000000000000000000000000001118 143.0
HFD1_k127_1072777_2 hmm pf04305 - - - 0.000004886 48.0
HFD1_k127_1072777_3 AsmA-like C-terminal region K07289 - - 0.0002431 53.0
HFD1_k127_1081517_0 Glycosyl transferases group 1 K02844 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 422.0
HFD1_k127_1081517_1 Glycosyltransferase family 9 (heptosyltransferase) K02841 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 321.0
HFD1_k127_1081517_2 heptosyltransferase K02843 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.000000000000000000000000000000000000000000000000000003441 196.0
HFD1_k127_1091454_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 532.0
HFD1_k127_1091454_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 381.0
HFD1_k127_1091454_2 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 321.0
HFD1_k127_1091454_3 involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 293.0
HFD1_k127_1091454_4 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000006514 213.0
HFD1_k127_1091454_5 Lipoprotein K04754 - - 0.0000000000000000000000000000001195 126.0
HFD1_k127_1091454_6 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000000000002636 96.0
HFD1_k127_1091454_7 dehydratase - - - 0.000001316 61.0
HFD1_k127_1092061_0 N-terminal domain of oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 409.0
HFD1_k127_1092061_1 Domain of unknown function DUF21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 365.0
HFD1_k127_1101833_0 aminopeptidase K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 572.0
HFD1_k127_1101833_1 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 428.0
HFD1_k127_1101833_10 Belongs to the UPF0149 family K09895 - - 0.0000000000001259 78.0
HFD1_k127_1101833_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 306.0
HFD1_k127_1101833_3 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K18800 - - 0.000000000000000000000000000000000000000000000000000000000000000000004267 249.0
HFD1_k127_1101833_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 GO:0001505,GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0017144,GO:0019464,GO:0019752,GO:0031405,GO:0031406,GO:0033293,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901681 - 0.0000000000000000000000000000000000000000000000000000007297 195.0
HFD1_k127_1101833_5 Polypeptide deformylase K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000001344 182.0
HFD1_k127_1101833_6 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.00000000000000000000000000000000000001294 152.0
HFD1_k127_1101833_7 PFAM N-formylglutamate amidohydrolase - - - 0.0000000000000000000000000002478 117.0
HFD1_k127_1101833_8 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000921,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032185,GO:0032505,GO:0032506,GO:0034622,GO:0042802,GO:0043093,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051301,GO:0061640,GO:0065003,GO:0070925,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - 0.000000000000000000006899 98.0
HFD1_k127_1101833_9 TIGRFAM TIGR02449 family protein K09892 - - 0.00000000000001189 77.0
HFD1_k127_1110974_0 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 541.0
HFD1_k127_1110974_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 353.0
HFD1_k127_1110974_10 membrane protein domain - - - 0.00000000000000000000007794 111.0
HFD1_k127_1110974_11 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.0000000000001769 76.0
HFD1_k127_1110974_2 helix_turn_helix, cAMP Regulatory protein K10914 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0007154,GO:0007584,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0017076,GO:0018130,GO:0019001,GO:0019219,GO:0019222,GO:0019438,GO:0030551,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0032553,GO:0032555,GO:0032561,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0035438,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045013,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045990,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140110,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 327.0
HFD1_k127_1110974_3 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 321.0
HFD1_k127_1110974_4 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007454 256.0
HFD1_k127_1110974_5 OsmC-like protein K07397 - - 0.00000000000000000000000000000000000000000000000000000000003135 208.0
HFD1_k127_1110974_6 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family K02503 - - 0.00000000000000000000000000000000000000002807 154.0
HFD1_k127_1110974_7 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate - - - 0.0000000000000000000000000000000000000103 151.0
HFD1_k127_1110974_8 - - - - 0.0000000000000000000000000000000000663 147.0
HFD1_k127_1110974_9 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000004264 138.0
HFD1_k127_1118959_0 Mitochondrial fission ELM1 K07276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009968 277.0
HFD1_k127_1118959_1 D-xylose 1-dehydrogenase (NADP+) activity - - - 0.00000000000000000000000000000000000000000000000000000000000004879 236.0
HFD1_k127_1118959_2 Macrocin-O-methyltransferase (TylF) - - - 0.00000000000000000000000000000000000000000000000000000000002074 214.0
HFD1_k127_1118959_3 Sulfotransferase family - - - 0.0000000000000000000000000000000000000002726 154.0
HFD1_k127_1118959_4 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000004911 92.0
HFD1_k127_1133654_0 UPF0313 protein - - - 0.0 1094.0
HFD1_k127_1133654_1 PFAM aminotransferase class V K00830,K00839 - 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 557.0
HFD1_k127_1133654_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 522.0
HFD1_k127_1133654_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 322.0
HFD1_k127_1133654_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003496 265.0
HFD1_k127_1133654_5 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000000006926 198.0
HFD1_k127_1133654_6 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000001043 175.0
HFD1_k127_114017_0 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate K00381 - 1.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 557.0
HFD1_k127_114017_1 Sodium hydrogen antiporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 421.0
HFD1_k127_114017_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 408.0
HFD1_k127_114017_3 peptidase K04774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 355.0
HFD1_k127_114017_4 COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding K03426 GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0033554,GO:0034641,GO:0035529,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.22 0.00000000000000000000000000000000000000008119 152.0
HFD1_k127_114017_5 Protein conserved in bacteria - - - 0.0000000000000000000000002551 113.0
HFD1_k127_114017_6 sterol carrier protein - - - 0.00000000001379 72.0
HFD1_k127_1166487_0 GTP-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 420.0
HFD1_k127_1166487_1 PFAM Glutathione S-transferase domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000231 281.0
HFD1_k127_1166487_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005072 290.0
HFD1_k127_1166487_3 Protein of unknown function (DUF2868) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008627 267.0
HFD1_k127_1166487_4 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000006051 233.0
HFD1_k127_1166487_5 Transmembrane secretion effector - - - 0.000000000000000000000000000000002292 137.0
HFD1_k127_1166487_6 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.00000000000000000000000000000002401 131.0
HFD1_k127_1166487_7 Gram-negative bacterial TonB protein C-terminal - - - 0.0000001211 65.0
HFD1_k127_1170930_0 TonB dependent receptor - - - 3.181e-219 706.0
HFD1_k127_1170930_1 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 355.0
HFD1_k127_1170930_2 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.00000000000005211 74.0
HFD1_k127_1185135_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 380.0
HFD1_k127_1185135_1 Cytochrome oxidase assembly protein K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 365.0
HFD1_k127_1185135_2 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000006894 190.0
HFD1_k127_1185135_3 SURF1-like protein K14998 - - 0.00000000000000000000000000000000000006172 152.0
HFD1_k127_1185135_4 signal sequence binding - - - 0.000000000000000000003311 105.0
HFD1_k127_1185135_5 Protein of unknown function (DUF2909) - - - 0.0000000000000474 75.0
HFD1_k127_1185961_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 394.0
HFD1_k127_1185961_1 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003922 288.0
HFD1_k127_1185961_2 Maf-like protein K06287 GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0047429 - 0.00000000000000003022 81.0
HFD1_k127_1188480_0 serine-type peptidase activity K01990,K08884,K12132,K18912 - 1.14.99.50,2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000004272 254.0
HFD1_k127_1188480_1 TIR domain - - - 0.000000000000000005718 99.0
HFD1_k127_1193133_0 COG0526, thiol-disulfide isomerase and thioredoxins - - - 5.083e-205 653.0
HFD1_k127_1193133_1 - - - - 0.000000000000000000000000000000004232 130.0
HFD1_k127_1193133_2 - - - - 0.0000000000000000000002154 98.0
HFD1_k127_1193133_3 - - - - 0.000000000000000001413 90.0
HFD1_k127_1208191_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 616.0
HFD1_k127_1208191_1 COG0811 Biopolymer transport proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000002724 241.0
HFD1_k127_1208191_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000000000000000000000000000000000000000000000002188 229.0
HFD1_k127_1208191_3 COG0848 Biopolymer transport protein - - - 0.0000000000000000000000000000000000000003129 156.0
HFD1_k127_1208191_4 TPR repeat - - - 0.0000000000000000000000000000000002937 142.0
HFD1_k127_1208191_5 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000008518 132.0
HFD1_k127_1208191_6 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000545 125.0
HFD1_k127_1208191_7 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0000000003086 66.0
HFD1_k127_1219160_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.327e-198 627.0
HFD1_k127_1219160_1 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.0000000000000000000000000000000000000003561 166.0
HFD1_k127_1219160_2 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K14160 - - 0.00000000000000000000000000009856 119.0
HFD1_k127_1219160_3 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division - - - 0.0000001293 58.0
HFD1_k127_1232569_0 DNA mediated transformation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008172 279.0
HFD1_k127_1232569_1 Glutathione S-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002824 254.0
HFD1_k127_1232569_2 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000001362 169.0
HFD1_k127_1232569_3 membrane transporter protein - - - 0.000000000000000002557 87.0
HFD1_k127_1249281_0 Peptidylprolyl isomerase K03770 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0061077,GO:0071575,GO:0071944,GO:0098552 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 346.0
HFD1_k127_1249281_1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 332.0
HFD1_k127_1249281_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000000002921 136.0
HFD1_k127_1265652_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 543.0
HFD1_k127_1265652_1 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 306.0
HFD1_k127_1265652_2 Penicillin-binding protein OB-like domain K05366 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000002735 259.0
HFD1_k127_1265652_3 50S ribosomal protein L31 K02909 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000008373 121.0
HFD1_k127_12717_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 496.0
HFD1_k127_12717_1 FeS assembly SUF system protein SufT - - - 0.000000000000000000000000000000000000000000000000000000000000003447 226.0
HFD1_k127_12717_2 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000003685 196.0
HFD1_k127_12717_3 ABC transporter K09013 - - 0.000000000000000000000000000000000000000002703 156.0
HFD1_k127_12717_4 Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system K05997,K13628 - - 0.00000000000000000000000000000233 124.0
HFD1_k127_12717_5 COG2166 SufE protein probably involved in Fe-S center assembly K02426 - - 0.000000000000000000004804 94.0
HFD1_k127_1271746_0 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000001515 229.0
HFD1_k127_1271746_1 Aspartyl Asparaginyl beta-hydroxylase K12979 - - 0.00000000000000000000000000000000005012 145.0
HFD1_k127_1271746_2 lactoylglutathione lyase activity - - - 0.0000000299 60.0
HFD1_k127_1276123_0 Aminotransferase class-III K16871 - 2.6.1.96 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 566.0
HFD1_k127_1276123_1 Methylamine dehydrogenase heavy chain (MADH) K15229 - 1.4.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005443 284.0
HFD1_k127_1276123_2 PFAM carboxyl transferase K15052 - 2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000003357 264.0
HFD1_k127_1276123_3 Methylamine dehydrogenase light chain K15228 - 1.4.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000009998 251.0
HFD1_k127_1276123_4 methylamine dehydrogenase accessory protein MauD - - - 0.0000000000000000000000000000000000000000000000000000005366 208.0
HFD1_k127_1276123_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.0000000000000000000000000000000009226 130.0
HFD1_k127_1276123_6 Cytochrome c - - - 0.0000000000000000000000000001415 119.0
HFD1_k127_1276123_7 Methylamine utilisation protein MauE - - - 0.0000000000000000000000001363 113.0
HFD1_k127_1277511_0 related to 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005373 494.0
HFD1_k127_1277511_1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000009244 208.0
HFD1_k127_1277511_2 glutathione transferase activity - - - 0.000000000000000000000000000000000000000000007257 170.0
HFD1_k127_1278763_0 Sugar (and other) transporter - - - 3.239e-214 677.0
HFD1_k127_1278763_1 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 367.0
HFD1_k127_1278763_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002581 269.0
HFD1_k127_1278763_3 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003877 262.0
HFD1_k127_1278763_4 NAD(P)H-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001079 250.0
HFD1_k127_1278763_5 F420H(2)-dependent quinone reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000004133 227.0
HFD1_k127_1278763_6 Beta-lactamase K01286 - 3.4.16.4 0.0000000000000000000000000003151 115.0
HFD1_k127_1278763_7 Beta-lactamase - - - 0.0000000000000184 76.0
HFD1_k127_1282684_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 2.379e-197 631.0
HFD1_k127_1282684_1 Succinyldiaminopimelate K14261,K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 506.0
HFD1_k127_1282684_2 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA K00674 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117 0.00000000000000000000000003022 113.0
HFD1_k127_1284990_0 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 379.0
HFD1_k127_1284990_1 ERAP1-like C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 389.0
HFD1_k127_1284990_2 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000004385 250.0
HFD1_k127_1294619_0 AraC-like ligand binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 466.0
HFD1_k127_1294619_1 dioxygenase alpha subunit K16319,K18242 - 1.14.12.1,1.14.13.172 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 452.0
HFD1_k127_1294619_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007653 252.0
HFD1_k127_1294619_3 carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004483 248.0
HFD1_k127_1294619_4 Ring hydroxylating beta subunit K16320,K18243 - 1.14.12.1,1.14.13.172 0.000000000000000000000000000000000000000003355 159.0
HFD1_k127_1294619_5 SnoaL-like domain - - - 0.0000000000000000000445 93.0
HFD1_k127_1294619_6 Flavin reductase like domain - - - 0.0000000000000000001345 91.0
HFD1_k127_1301034_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 437.0
HFD1_k127_1301034_1 PFAM amidohydrolase 2 K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 316.0
HFD1_k127_1301034_2 Enoyl-(Acyl carrier protein) reductase K03366 - 1.1.1.304,1.1.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 317.0
HFD1_k127_1301034_3 Ring hydroxylating alpha subunit (catalytic domain) K10619 - 1.14.12.25 0.00000000000000000000000000000000000000000000000000000000000001034 218.0
HFD1_k127_1301034_4 Ring hydroxylating beta subunit K16303 - 1.14.12.25 0.00000000000000000000000000000000000000000000009451 181.0
HFD1_k127_1301034_5 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.000000000000000000000000000004251 122.0
HFD1_k127_1302729_0 ABC transporter - - - 3.495e-272 847.0
HFD1_k127_1302729_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002516 262.0
HFD1_k127_1305185_0 tRNA synthetases class I (E and Q), catalytic domain K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 309.0
HFD1_k127_1305185_1 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000001882 236.0
HFD1_k127_1305185_2 Belongs to the SfsA family K06206 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005975,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0044238,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000001735 176.0
HFD1_k127_1305185_3 ATP-binding region ATPase domain protein K03407 - 2.7.13.3 0.0005003 45.0
HFD1_k127_1316936_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009115 554.0
HFD1_k127_1316936_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 532.0
HFD1_k127_1316936_2 COG1960 Acyl-CoA dehydrogenases K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 442.0
HFD1_k127_1316936_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 434.0
HFD1_k127_1316936_4 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008255 282.0
HFD1_k127_1316936_5 Protein of unknown function (DUF2628) - - - 0.0000000000000000008024 93.0
HFD1_k127_1319437_0 Sulfotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006688 297.0
HFD1_k127_1319437_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000001871 222.0
HFD1_k127_1319437_2 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000002517 227.0
HFD1_k127_1319437_3 lactoylglutathione lyase activity K05606 - 5.1.99.1 0.000000000000000000001189 104.0
HFD1_k127_1335821_0 Acetyl-CoA acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 520.0
HFD1_k127_1335821_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 454.0
HFD1_k127_1335821_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 395.0
HFD1_k127_1335821_3 ABC transporter, ATP-binding protein K01990 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006855,GO:0008150,GO:0015562,GO:0015893,GO:0016020,GO:0022857,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000001507 232.0
HFD1_k127_1335821_4 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.00000000000000003522 83.0
HFD1_k127_1401733_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 461.0
HFD1_k127_1401733_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004798 341.0
HFD1_k127_1401733_10 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000001707 109.0
HFD1_k127_1401733_11 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000002629 88.0
HFD1_k127_1401733_12 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000001815 80.0
HFD1_k127_1401733_2 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 289.0
HFD1_k127_1401733_3 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000006336 244.0
HFD1_k127_1401733_4 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000006269 216.0
HFD1_k127_1401733_5 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000007356 169.0
HFD1_k127_1401733_6 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000000762 159.0
HFD1_k127_1401733_7 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000132 156.0
HFD1_k127_1401733_8 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000009062 120.0
HFD1_k127_1401733_9 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000001421 115.0
HFD1_k127_1417573_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 5.511e-280 875.0
HFD1_k127_1417573_1 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000001104 147.0
HFD1_k127_142697_0 Phosphoglucose isomerase K01810 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.3.1.9 5.642e-278 866.0
HFD1_k127_142697_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 530.0
HFD1_k127_142697_2 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 508.0
HFD1_k127_142697_3 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 330.0
HFD1_k127_142697_4 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576 6.5.1.2 0.000000000000000000000000000000000000000000000000000000207 197.0
HFD1_k127_142697_5 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 0.00000003014 65.0
HFD1_k127_1430732_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 554.0
HFD1_k127_1430732_1 NADP-dependent K00001,K07119 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 490.0
HFD1_k127_1430732_2 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 367.0
HFD1_k127_1430732_3 protease with the C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 314.0
HFD1_k127_1430732_4 PFAM Glutathione S-transferase domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000002395 198.0
HFD1_k127_1430732_5 Metal dependent phosphohydrolases with conserved 'HD' motif. K21196 - 1.13.11.78 0.00000000000000000000000000000000000000000000000000105 188.0
HFD1_k127_1436222_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0009636,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042221,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0050896,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:1901264 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 495.0
HFD1_k127_1436222_1 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564 5.2.1.8 0.000000000000000000000003046 108.0
HFD1_k127_1448324_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000004292 216.0
HFD1_k127_1448324_1 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000005447 211.0
HFD1_k127_1448324_2 Polyketide cyclase / dehydrase and lipid transport - GO:0003674,GO:0005488,GO:0006417,GO:0006446,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044877,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000001422 157.0
HFD1_k127_1448324_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0030674,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042221,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045203,GO:0045229,GO:0046677,GO:0050896,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0060090,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0000000000000000000000000006425 118.0
HFD1_k127_1448324_4 Belongs to the UPF0125 (RnfH) family K09801 - - 0.0000000000000001724 83.0
HFD1_k127_1458836_0 Participates in both transcription termination and antitermination K02600 GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 1.352e-221 696.0
HFD1_k127_1458836_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002106 261.0
HFD1_k127_1458836_2 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000002621 186.0
HFD1_k127_1458836_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000001147 136.0
HFD1_k127_1458836_4 Preprotein translocase subunit SecG K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000000003713 98.0
HFD1_k127_1458836_5 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000002459 62.0
HFD1_k127_1461909_0 Transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 344.0
HFD1_k127_1461909_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 295.0
HFD1_k127_1461909_2 OmpW family K07275 - - 0.0000000000000000000000000000000000000000004418 166.0
HFD1_k127_1461909_3 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000001789 155.0
HFD1_k127_1461909_4 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000001219 130.0
HFD1_k127_1461909_5 Activator of Hsp90 ATPase 1 family protein - - - 0.0000000000006156 70.0
HFD1_k127_1469220_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002974 277.0
HFD1_k127_1469220_1 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000004744 169.0
HFD1_k127_1469220_2 Flavinator of succinate dehydrogenase K09159 GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006105,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016043,GO:0016999,GO:0017013,GO:0017144,GO:0018065,GO:0018293,GO:0019538,GO:0019752,GO:0022607,GO:0034552,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043648,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0045333,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072350,GO:1901564 - 0.00000000000000002774 87.0
HFD1_k127_1469220_3 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.0000000000001986 71.0
HFD1_k127_1474194_0 Belongs to the heme-copper respiratory oxidase family K00404 GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.9.3.1 8.881e-264 818.0
HFD1_k127_1474194_1 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 313.0
HFD1_k127_1474194_2 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 294.0
HFD1_k127_1474194_3 COG0348 Polyferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002744 276.0
HFD1_k127_1474194_4 COG0589 Universal stress protein UspA and related K14055 - - 0.0002103 45.0
HFD1_k127_1494681_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 604.0
HFD1_k127_1494681_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 533.0
HFD1_k127_1494681_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 470.0
HFD1_k127_1494681_3 Belongs to the GppA Ppx family K01524 GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006797,GO:0006798,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008894,GO:0009056,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034641,GO:0042594,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:1901360,GO:1901575 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 388.0
HFD1_k127_1494681_4 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0000000000000000000000000000000000000000000000000002547 187.0
HFD1_k127_1494681_5 SNARE associated golgi protein - - - 0.00000000000000000000000000000000000004311 151.0
HFD1_k127_1494681_6 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000001387 125.0
HFD1_k127_1494681_7 Luciferase-like monooxygenase - - - 0.00000000000000000000000003741 108.0
HFD1_k127_1504970_0 Aminotransferase class-III K00822 - 2.6.1.18 5.998e-208 652.0
HFD1_k127_1510326_0 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 447.0
HFD1_k127_1510326_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 371.0
HFD1_k127_1514469_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 501.0
HFD1_k127_1529212_0 Phytanoyl-CoA dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 339.0
HFD1_k127_1529212_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 287.0
HFD1_k127_1529212_2 glutathione transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000004847 221.0
HFD1_k127_1529212_3 Glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000000000000000000000000000982 173.0
HFD1_k127_1529212_4 PFAM aminoglycoside phosphotransferase K18844 - - 0.00000000000000000000176 96.0
HFD1_k127_1577865_0 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009448 434.0
HFD1_k127_1577865_1 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009718 410.0
HFD1_k127_1577865_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000005121 255.0
HFD1_k127_1577865_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000008134 179.0
HFD1_k127_1587209_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 491.0
HFD1_k127_1587209_1 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 451.0
HFD1_k127_1593828_0 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 391.0
HFD1_k127_1593828_1 Belongs to the DegT DnrJ EryC1 family K16016 - 4.2.1.144 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 351.0
HFD1_k127_1593828_2 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 326.0
HFD1_k127_1593828_3 PFAM cation efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008003 254.0
HFD1_k127_1593828_4 - - - - 0.000000000000000000000000000000000000000000000000000000003687 204.0
HFD1_k127_1593828_5 Biogenesis protein - - - 0.000000000000000000000000000000000000000000000000001171 192.0
HFD1_k127_1593828_6 Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000002738 155.0
HFD1_k127_1593828_7 Metal-sensitive transcriptional repressor K07807 - - 0.000000000000000000000000000009566 121.0
HFD1_k127_1593828_8 PFAM glutathione-dependent formaldehyde-activating GFA - - - 0.00000000000000000000000000007532 120.0
HFD1_k127_1593828_9 N-acetylglucosaminylinositol deacetylase activity - - - 0.00000000000000000000000000158 128.0
HFD1_k127_160984_0 cation transport ATPase K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 501.0
HFD1_k127_160984_1 IG-like fold at C-terminal of FixG, putative oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 301.0
HFD1_k127_160984_2 FixH K09926 - - 0.00003266 55.0
HFD1_k127_1632006_0 Membrane-bound serine protease (ClpP class) K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 483.0
HFD1_k127_1632006_1 PFAM SPFH domain Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 368.0
HFD1_k127_1632006_2 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 349.0
HFD1_k127_1632006_3 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 346.0
HFD1_k127_1632006_4 Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 327.0
HFD1_k127_1632006_5 Cysteine synthase K01697,K01738 - 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 293.0
HFD1_k127_1632006_6 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 290.0
HFD1_k127_1638774_0 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 426.0
HFD1_k127_1638774_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002126 285.0
HFD1_k127_1638774_2 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000008429 192.0
HFD1_k127_1638774_4 dioxygenase activity - - - 0.0000000001507 66.0
HFD1_k127_1639219_0 transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000398 284.0
HFD1_k127_1639219_1 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000007591 199.0
HFD1_k127_1643318_0 MlrC C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 613.0
HFD1_k127_1643318_1 POT family K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 568.0
HFD1_k127_1643318_2 dehydratase K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 535.0
HFD1_k127_1643318_3 cytochrome P-450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008759 509.0
HFD1_k127_1643318_4 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 362.0
HFD1_k127_1643318_5 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 342.0
HFD1_k127_1643318_6 alcohol dehydrogenase K00004 - 1.1.1.303,1.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 288.0
HFD1_k127_1643318_7 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic domain K01886 - 6.1.1.18 0.000000000000000000000000000000000000000000000000000004915 196.0
HFD1_k127_1643318_8 - - - - 0.000000000000001355 80.0
HFD1_k127_1643318_9 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000002368 61.0
HFD1_k127_1650833_0 Circularly permuted ATP-grasp type 2 - - - 1.449e-221 697.0
HFD1_k127_1650833_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 348.0
HFD1_k127_1650833_2 A predicted alpha-helical domain with a conserved ER motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004941 271.0
HFD1_k127_1650833_3 Methyltransferase - - - 0.0000000000000000000000000000000000000000000005597 170.0
HFD1_k127_1650833_4 Alpha beta hydrolase K14731 - 3.1.1.83 0.000000000001275 68.0
HFD1_k127_1652863_0 acyl-CoA dehydrogenase K00248,K00249 - 1.3.8.1,1.3.8.7 5.652e-241 749.0
HFD1_k127_1652863_1 COG1020 Non-ribosomal peptide synthetase modules and related proteins - - - 6.714e-200 633.0
HFD1_k127_1652863_2 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 571.0
HFD1_k127_1652863_3 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 419.0
HFD1_k127_1652863_4 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 407.0
HFD1_k127_1652863_5 phosphinothricin N-acetyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001729 273.0
HFD1_k127_1652863_6 Bacterial regulatory proteins, crp family K10914 - - 0.0000000000000000000000000000000000000000000004152 176.0
HFD1_k127_1652863_7 response to stress - - - 0.000000000000000000000000000000259 133.0
HFD1_k127_1652863_8 LysM domain - - - 0.0000000000000000000000002785 116.0
HFD1_k127_166998_0 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 465.0
HFD1_k127_166998_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003248 264.0
HFD1_k127_1689839_0 PFAM amidohydrolase 2 K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 426.0
HFD1_k127_1689839_1 PFAM Amidohydrolase 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 428.0
HFD1_k127_1689839_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005963 421.0
HFD1_k127_1689839_3 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000001279 214.0
HFD1_k127_1689839_4 - - - - 0.000000000000000000000000000000000000000000000000000007027 197.0
HFD1_k127_1689839_5 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000001077 168.0
HFD1_k127_1689839_6 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000001513 153.0
HFD1_k127_1689839_7 - - - - 0.00000000000000000000000000003356 120.0
HFD1_k127_1689839_8 MaoC like domain - - - 0.000000002097 67.0
HFD1_k127_1689839_9 N-terminal half of MaoC dehydratase - - - 0.0001254 50.0
HFD1_k127_1699443_0 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0008780,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 325.0
HFD1_k127_1699443_1 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000002986 202.0
HFD1_k127_1699443_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000009207 171.0
HFD1_k127_1701939_0 Lanthionine synthetase C-like protein - - - 0.00000000000000000000000000000000000000000000000001737 184.0
HFD1_k127_1701939_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000003402 158.0
HFD1_k127_1701939_2 Lanthionine synthetase C-like protein - - - 0.000000000000000000000000000003734 125.0
HFD1_k127_1701939_3 ferredoxin K04755 - - 0.00000000000000000000000000004168 120.0
HFD1_k127_1701939_4 Selenoprotein B glycine betaine sarcosine D-proline reductase K10794 - 1.21.4.1 0.00000000000000000000005019 104.0
HFD1_k127_1701939_5 - - - - 0.00000004626 58.0
HFD1_k127_1701939_6 acyl-CoA transferases carnitine dehydratase - - - 0.0000001815 53.0
HFD1_k127_1703833_0 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 323.0
HFD1_k127_1703833_1 Conserved hypothetical protein (DUF2461) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003659 259.0
HFD1_k127_1703833_2 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 0.0000000000000000000000000000000001022 134.0
HFD1_k127_1711789_0 PFAM deoxyhypusine synthase K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 524.0
HFD1_k127_1711789_1 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 392.0
HFD1_k127_1711789_2 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001069 244.0
HFD1_k127_1711789_3 PFAM Orn DAP Arg decarboxylase 2 K01585 - 4.1.1.19 0.00000000000000000000000000000000000003495 160.0
HFD1_k127_1736760_0 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 327.0
HFD1_k127_1736760_1 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001762 283.0
HFD1_k127_1750944_0 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272,K21344 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008219,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0012501,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016779,GO:0019200,GO:0033692,GO:0033785,GO:0033786,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0070566,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 490.0
HFD1_k127_1750944_1 Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 322.0
HFD1_k127_1750944_2 Aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002567 273.0
HFD1_k127_1750944_3 oxidoreductase() - - - 0.000000000000000000000000000000000000000000000000000522 191.0
HFD1_k127_1750944_4 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000001069 170.0
HFD1_k127_1766639_0 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001615 261.0
HFD1_k127_1766639_1 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000000000000000000000000000000000000000000000001072 240.0
HFD1_k127_1766639_2 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000002515 231.0
HFD1_k127_1766639_3 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000000000000004124 164.0
HFD1_k127_1766639_4 - - - - 0.00000000003867 75.0
HFD1_k127_1766639_5 - - - - 0.000000001171 64.0
HFD1_k127_1766639_6 regulatory protein, FmdB family - - - 0.000006504 51.0
HFD1_k127_1782320_0 Domain of unknown function (DUF3413) K07014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 426.0
HFD1_k127_1782320_1 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 348.0
HFD1_k127_1782320_2 Protein tyrosine serine phosphatase - - - 0.00000000000000000000000007777 116.0
HFD1_k127_1782320_3 TPR repeat - - - 0.000002452 51.0
HFD1_k127_1782489_0 nitrogen regulation protein K07712 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 519.0
HFD1_k127_1782489_1 Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate K09018 GO:0003674,GO:0003824,GO:0004497,GO:0006139,GO:0006206,GO:0006208,GO:0006210,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016491,GO:0017144,GO:0019740,GO:0019859,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0052614,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.14.99.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 375.0
HFD1_k127_1785296_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001395 265.0
HFD1_k127_1785296_1 nitroreductase - - - 0.00000000000000000000000000000000002208 154.0
HFD1_k127_1789275_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 552.0
HFD1_k127_1789275_1 Carboxyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 473.0
HFD1_k127_1789275_2 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000001777 239.0
HFD1_k127_1790221_0 carnitine dehydratase K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 522.0
HFD1_k127_1790221_1 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01908 - 6.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 368.0
HFD1_k127_1790221_2 ABC transporter K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000192 268.0
HFD1_k127_1790221_3 - - - - 0.0000000000000000000000000000000000000001083 156.0
HFD1_k127_1810081_0 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004088 446.0
HFD1_k127_1810081_1 Secretory lipase - - - 0.0000000000000000000000000000000000000000000000000000000000000002225 243.0
HFD1_k127_1810081_2 2-hydroxychromene-2-carboxylate isomerase K14584 - 5.99.1.4 0.0000000000000000000000000000000000000000000000000000009962 198.0
HFD1_k127_1810081_3 Dehydrogenase - - - 0.000000000000000000000000000000000006509 147.0
HFD1_k127_1831010_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 2.558e-204 643.0
HFD1_k127_1831010_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007276 450.0
HFD1_k127_1831010_2 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.000000000000000000000000000000005709 136.0
HFD1_k127_1839329_0 Inorganic H+ pyrophosphatase K15987 - 3.6.1.1 1.056e-316 981.0
HFD1_k127_1839329_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 8.938e-208 653.0
HFD1_k127_1839329_2 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 533.0
HFD1_k127_1839329_3 - - - - 0.00000000001837 71.0
HFD1_k127_1860568_0 Flavin-binding monooxygenase-like K03379 - 1.14.13.22 0.0 1037.0
HFD1_k127_1860568_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 449.0
HFD1_k127_1860568_2 beta-lactamase - - - 0.000000000000001176 78.0
HFD1_k127_1860568_3 dioxygenase activity K00477 - 1.14.11.18 0.00000008585 54.0
HFD1_k127_18757_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 420.0
HFD1_k127_18757_1 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000002195 199.0
HFD1_k127_18757_2 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia K01426 - 3.5.1.4 0.0000000000000000008298 87.0
HFD1_k127_1876269_0 Carboxyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 366.0
HFD1_k127_1876269_1 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007465 296.0
HFD1_k127_1876269_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000001893 225.0
HFD1_k127_1876274_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0 1438.0
HFD1_k127_1876274_1 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 607.0
HFD1_k127_1876274_10 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000001095 136.0
HFD1_k127_1876274_11 to the N-terminal domain of Lon protease K07157 - - 0.000000000000000000000001313 108.0
HFD1_k127_1876274_12 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000001022 97.0
HFD1_k127_1876274_13 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.0000000000000959 74.0
HFD1_k127_1876274_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 547.0
HFD1_k127_1876274_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0016020,GO:0022603,GO:0022604,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 416.0
HFD1_k127_1876274_4 lytic murein transglycosylase B K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 377.0
HFD1_k127_1876274_5 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000004285 242.0
HFD1_k127_1876274_6 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000006666 240.0
HFD1_k127_1876274_7 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000000000001419 202.0
HFD1_k127_1876274_8 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K01488 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.5.4.4 0.000000000000000000000000000000000000000000000005694 182.0
HFD1_k127_1876274_9 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000009361 178.0
HFD1_k127_1876334_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 3.16e-321 993.0
HFD1_k127_1876334_1 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000002975 225.0
HFD1_k127_1876334_2 Integral membrane protein (DUF2244) - - - 0.00000000000000000000000002755 115.0
HFD1_k127_1879631_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006121 573.0
HFD1_k127_1879631_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 557.0
HFD1_k127_1879631_2 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008377 492.0
HFD1_k127_1879631_3 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000000000000003077 167.0
HFD1_k127_1879631_4 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.000000000000000000000000000000000003287 144.0
HFD1_k127_1879631_5 sulfur relay protein TusD DsrE K07235 - - 0.00000000000000000000000000000007968 130.0
HFD1_k127_1879631_6 Sulfur relay protein TusC DsrF K07236 - - 0.00000000000000001447 91.0
HFD1_k127_1879631_7 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions K07237 GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.0001938 48.0
HFD1_k127_1886175_0 chromosome segregation K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003792 282.0
HFD1_k127_1886175_1 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005766 246.0
HFD1_k127_1886175_2 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000000000000001445 158.0
HFD1_k127_1886175_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000001934 84.0
HFD1_k127_1886175_4 - - - - 0.000000000001105 77.0
HFD1_k127_1887241_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 4.415e-196 619.0
HFD1_k127_1887241_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000002389 253.0
HFD1_k127_1887241_2 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.0000000000000000000000000000000000000000004296 165.0
HFD1_k127_1887241_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000004546 160.0
HFD1_k127_1887241_4 Belongs to the BolA IbaG family - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - 0.0000000001099 66.0
HFD1_k127_1887241_5 NTP binding protein (Contains STAS domain) K07122 - - 0.0008665 48.0
HFD1_k127_1899630_0 cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000956 602.0
HFD1_k127_1899630_1 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.00000000000000000000000000000000000002589 149.0
HFD1_k127_1903809_0 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 310.0
HFD1_k127_1903809_1 Belongs to the aminoglycoside phosphotransferase family K19300 - 2.7.1.95 0.000000000000000000000000000000000000000000000000000008626 197.0
HFD1_k127_1915291_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 2103.0
HFD1_k127_1927480_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 354.0
HFD1_k127_1927480_1 SMP-30/Gluconolaconase/LRE-like region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 313.0
HFD1_k127_1927480_2 - - - - 0.000000000000000000000000000000000000000000000007539 193.0
HFD1_k127_1948119_0 Pfam Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000573 372.0
HFD1_k127_1948119_1 Methyltransferase domain - - - 0.000000000000000000000000001773 121.0
HFD1_k127_1957347_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 7.726e-198 631.0
HFD1_k127_1957347_1 Phosphoglycerate mutase family - - - 0.00000003268 63.0
HFD1_k127_1961531_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 499.0
HFD1_k127_1961531_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 334.0
HFD1_k127_1961531_2 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000005047 190.0
HFD1_k127_1961531_3 Cupin domain - - - 0.000000000000000000000000000000000000000000000002764 177.0
HFD1_k127_1961531_4 MAPEG family - - - 0.00000000000000000000844 98.0
HFD1_k127_1999738_0 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 310.0
HFD1_k127_1999738_1 beta-lactamase - - - 0.000001412 49.0
HFD1_k127_2007422_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 554.0
HFD1_k127_2007422_1 FR47-like protein - - - 0.000002641 51.0
HFD1_k127_2013757_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.634e-201 643.0
HFD1_k127_2013757_1 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008776,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016741,GO:0016742,GO:0016772,GO:0016774,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 572.0
HFD1_k127_2013757_2 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000000000009569 235.0
HFD1_k127_2019132_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 1.469e-299 939.0
HFD1_k127_2019132_1 Belongs to the aspartokinase family K00928 GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 538.0
HFD1_k127_2019132_2 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005979,GO:0006109,GO:0006139,GO:0006417,GO:0006446,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010675,GO:0010677,GO:0010906,GO:0010962,GO:0016070,GO:0016071,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032881,GO:0032885,GO:0034248,GO:0034249,GO:0034641,GO:0043170,GO:0043255,GO:0043467,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045719,GO:0045912,GO:0045947,GO:0046483,GO:0048027,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0062012,GO:0065007,GO:0070873,GO:0070874,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.00000000000000000000000004682 108.0
HFD1_k127_2029308_0 PrkA AAA domain K07180 GO:0003674,GO:0003824,GO:0004672,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0042594,GO:0043170,GO:0043412,GO:0043562,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - 0.0 1108.0
HFD1_k127_2029308_1 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 GO:0003674,GO:0003824,GO:0004551,GO:0004721,GO:0006139,GO:0006464,GO:0006470,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0008796,GO:0008803,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015949,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0019538,GO:0034641,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0140096,GO:1901360,GO:1901564 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 303.0
HFD1_k127_2029308_2 Belongs to the UPF0229 family K09786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002671 245.0
HFD1_k127_2039586_0 Ring hydroxylating alpha subunit (catalytic domain) K00499,K22443 - 1.14.13.239,1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 377.0
HFD1_k127_2039586_1 COG2202 FOG PAS PAC domain - - - 0.00000000000000000000000000000000000000000000001935 177.0
HFD1_k127_2039586_2 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000000000000000034 169.0
HFD1_k127_2040652_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 2.179e-249 780.0
HFD1_k127_2058288_0 P-aminobenzoate N-oxygenase AurF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 501.0
HFD1_k127_2058288_1 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000006535 211.0
HFD1_k127_2058288_2 COG3552 Protein containing von Willebrand factor type A (vWA) domain K07161 - - 0.000000000000000000000004043 109.0
HFD1_k127_2071817_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1205.0
HFD1_k127_2071817_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000001376 221.0
HFD1_k127_2071817_2 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000002854 168.0
HFD1_k127_2085433_0 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 377.0
HFD1_k127_2085433_1 Belongs to the TPP enzyme family K01652 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0019752,GO:0030312,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.2.1.6 0.0000000000000000000000000000000000000000009925 161.0
HFD1_k127_2085433_2 - - - - 0.0000000000000307 76.0
HFD1_k127_2087181_0 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities K14155 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 384.0
HFD1_k127_2087181_1 COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000002932 247.0
HFD1_k127_2106736_0 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 372.0
HFD1_k127_2106736_1 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001169 288.0
HFD1_k127_2125230_0 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001453 259.0
HFD1_k127_2125230_1 PFAM Fatty acid hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000006811 248.0
HFD1_k127_2125230_2 very-long-chain-acyl-CoA dehydrogenase activity K17880 - 2.7.1.119 0.00000000000000000000000001322 116.0
HFD1_k127_2125230_3 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000004531 80.0
HFD1_k127_2125976_0 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008209 445.0
HFD1_k127_2125976_1 Methylamine dehydrogenase heavy chain (MADH) K15229 - 1.4.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 295.0
HFD1_k127_2125976_2 Methylamine dehydrogenase, L chain K15228 - 1.4.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 283.0
HFD1_k127_2125976_3 UPF0114 protein - - - 0.00000002403 55.0
HFD1_k127_2127995_0 DNA polymerase type-B family K02336 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000783 629.0
HFD1_k127_2127995_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006329 557.0
HFD1_k127_2127995_2 HlyD membrane-fusion protein of T1SS - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002464 273.0
HFD1_k127_2127995_3 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000000000000000000000306 129.0
HFD1_k127_2132251_0 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 455.0
HFD1_k127_2132251_1 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000001812 278.0
HFD1_k127_2132251_2 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003052 248.0
HFD1_k127_2132251_3 Protein of unknown function (DUF3237) - - - 0.000000000000000000000000000000001115 131.0
HFD1_k127_2132251_4 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000128 111.0
HFD1_k127_2132251_5 - - - - 0.000000002358 65.0
HFD1_k127_2132882_0 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 515.0
HFD1_k127_2132882_1 Glycerol-3-phosphate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006849 464.0
HFD1_k127_2132882_10 receptor - - - 0.0002145 49.0
HFD1_k127_2132882_2 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 399.0
HFD1_k127_2132882_3 phosphoprotein phosphatase activity - - - 0.00000000000000000000000000000000000000001271 169.0
HFD1_k127_2132882_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K12256 - 2.6.1.113 0.0000000000000000000000000000000000005769 141.0
HFD1_k127_2132882_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000002839 132.0
HFD1_k127_2132882_6 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit K00334,K03943 - 1.6.5.3,1.6.99.3 0.0000000000002786 84.0
HFD1_k127_2132882_7 TonB dependent receptor K02014 - - 0.000000006526 68.0
HFD1_k127_2132882_8 lactoylglutathione lyase activity K05606 - 5.1.99.1 0.000001011 57.0
HFD1_k127_2132882_9 - - - - 0.00003895 53.0
HFD1_k127_2147505_0 Belongs to the NadC ModD family K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 338.0
HFD1_k127_2147505_1 ROK family K00845,K00847 - 2.7.1.2,2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000006689 239.0
HFD1_k127_2147505_2 COG3023 Negative regulator of beta-lactamase expression K01447,K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043170,GO:0044424,GO:0044464,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000002185 220.0
HFD1_k127_2147505_3 - - - - 0.00000000000000000002721 105.0
HFD1_k127_2153507_0 Bacterial protein of unknown function (DUF853) K06915 - - 3.463e-194 618.0
HFD1_k127_2153507_1 COG2211 Na melibiose symporter and related transporters - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 432.0
HFD1_k127_2153507_2 Protein of unknown function (DUF2167) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005748 265.0
HFD1_k127_2153507_3 Pfam:DUF385 - - - 0.0000000000000000000000000000005833 127.0
HFD1_k127_2155222_0 Protein of unknown function - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 351.0
HFD1_k127_2155222_1 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000007029 222.0
HFD1_k127_2180959_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 4.76e-293 913.0
HFD1_k127_2180959_1 AMP-dependent synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 485.0
HFD1_k127_2180959_2 Vacuole effluxer Atg22 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007005 459.0
HFD1_k127_2180959_3 (ABC) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004987 437.0
HFD1_k127_2180959_4 'Cold-shock' DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000002872 199.0
HFD1_k127_2180959_5 - - - - 0.000000000000000000000000000000000000000000000006253 178.0
HFD1_k127_2180959_7 - - - - 0.00000006486 58.0
HFD1_k127_2191964_0 Transmembrane secretion effector - - - 2.697e-233 735.0
HFD1_k127_2191964_1 Alpha beta hydrolase K15756 - 3.7.1.13 0.00000000000000000000000000000000001212 147.0
HFD1_k127_2219987_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051301,GO:0051704,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 402.0
HFD1_k127_2219987_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004486,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0055114,GO:0071704,GO:1901360,GO:1901564 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 394.0
HFD1_k127_2219987_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 391.0
HFD1_k127_2219987_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 306.0
HFD1_k127_2219987_4 COG4445 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA K06169 - - 0.0000000000000000000000000000000000000000000000000000000000000005459 228.0
HFD1_k127_2219987_5 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000001451 220.0
HFD1_k127_2219987_6 Fe-S protein K06938 - - 0.0000000000000000000000000009103 117.0
HFD1_k127_2219987_8 - - - - 0.0000001403 58.0
HFD1_k127_2219987_9 - - - - 0.000001835 49.0
HFD1_k127_2221194_0 lactate/malate dehydrogenase, NAD binding domain K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 523.0
HFD1_k127_2221194_1 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000004198 89.0
HFD1_k127_2221194_2 - - - - 0.0001213 53.0
HFD1_k127_2226747_0 - K20614 - 4.2.1.127,5.4.4.4 2.454e-199 639.0
HFD1_k127_2226747_1 Tannase and feruloyl esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000224 249.0
HFD1_k127_2226747_2 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000001065 162.0
HFD1_k127_2226747_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000001772 111.0
HFD1_k127_2229448_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006869,GO:0008144,GO:0008150,GO:0008289,GO:0008559,GO:0009987,GO:0010876,GO:0015221,GO:0015238,GO:0015399,GO:0015405,GO:0015437,GO:0015893,GO:0015920,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034040,GO:0034204,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042802,GO:0042908,GO:0042910,GO:0043167,GO:0043168,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0071702,GO:0071840,GO:0071944,GO:0097035,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901265,GO:1901363,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009977 616.0
HFD1_k127_2229448_1 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009758 449.0
HFD1_k127_2229448_2 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 315.0
HFD1_k127_2229448_3 MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007631 277.0
HFD1_k127_2229448_4 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002255 275.0
HFD1_k127_2229448_5 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000000000003696 145.0
HFD1_k127_2234037_0 Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP) K00209 - 1.3.1.44,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007979 481.0
HFD1_k127_2234037_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 334.0
HFD1_k127_2234037_2 PFAM ATP-NAD AcoX kinase - - - 0.000000000000000000000000000000000000000000000000000001396 203.0
HFD1_k127_2234037_3 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000082 179.0
HFD1_k127_2239654_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 580.0
HFD1_k127_2239654_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 453.0
HFD1_k127_2239654_2 May be the GTPase, regulating ATP sulfurylase activity K00955 GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0044237 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 293.0
HFD1_k127_2239654_3 Cytochrome b/b6/petB - - - 0.000000000000000000000000000000000000000000000000000000000406 211.0
HFD1_k127_2239654_4 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.00000000000000000000000000000000000000000000000000002461 191.0
HFD1_k127_224712_0 Flavin-binding monooxygenase-like K03379 - 1.14.13.22 7.08e-203 643.0
HFD1_k127_224712_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 347.0
HFD1_k127_2252315_0 Transport of potassium into the cell K03549 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 530.0
HFD1_k127_2252315_1 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008826 478.0
HFD1_k127_2252315_2 Protein of unknown function (DUF3450) - - - 0.00000000000000000000000000000000000000000000000000000000000169 218.0
HFD1_k127_2252315_3 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000005061 148.0
HFD1_k127_2252315_4 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000000000001858 123.0
HFD1_k127_2268394_0 Flavin-binding monooxygenase-like K03379 - 1.14.13.22 3.283e-223 704.0
HFD1_k127_2268394_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000006481 204.0
HFD1_k127_2268394_2 N-Acyl-D-aspartate D-glutamate deacylase - - - 0.000000000000009395 75.0
HFD1_k127_2269992_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 329.0
HFD1_k127_2269992_1 MmgE/PrpD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004443 271.0
HFD1_k127_2269992_2 Tetratricopeptide repeat - - - 0.00000000000000000000000002255 121.0
HFD1_k127_2277322_0 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 507.0
HFD1_k127_2277322_1 TIGRFAM Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 417.0
HFD1_k127_2277322_2 Belongs to the P(II) protein family K04751,K04752 - - 0.000000000000000000000000000000000000000000000000000000001617 201.0
HFD1_k127_2277322_3 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000000000000000000000000000000000000000000006809 174.0
HFD1_k127_2277322_4 COG3245 Cytochrome c5 K02277 - 1.9.3.1 0.00000000000000000000000000000006092 128.0
HFD1_k127_2277322_6 Membrane fusogenic activity K09806 - - 0.0001065 48.0
HFD1_k127_2279554_0 D-arabinono-1,4-lactone oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 336.0
HFD1_k127_2279554_1 of the major facilitator superfamily - - - 0.000000000000000000000000000003029 128.0
HFD1_k127_2279608_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 3.702e-196 623.0
HFD1_k127_2279608_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000004289 111.0
HFD1_k127_2279608_2 Beta-lactamase - - - 0.00000000000000000000000008521 113.0
HFD1_k127_2286675_0 Peptidase family M1 domain K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 303.0
HFD1_k127_2286675_1 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003255 257.0
HFD1_k127_2286709_0 ABC transporter transmembrane region K06147,K18890 - - 1.26e-211 672.0
HFD1_k127_2286709_1 COG2211 Na melibiose symporter and related transporters - - - 0.000000000000000000000000000000000000000000000001965 182.0
HFD1_k127_2309891_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 551.0
HFD1_k127_2309891_1 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003261 268.0
HFD1_k127_2309891_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000002025 224.0
HFD1_k127_2309891_3 Major Facilitator K08369 - - 0.0000000001898 72.0
HFD1_k127_2325130_0 Cobalamin biosynthesis protein CobT VWA domain K09883 - 6.6.1.2 7.094e-211 672.0
HFD1_k127_2325130_1 Cobaltochelatase CobS subunit N terminal K09882 - 6.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 521.0
HFD1_k127_2325130_2 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 429.0
HFD1_k127_2337297_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 9.49e-220 693.0
HFD1_k127_2337297_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 309.0
HFD1_k127_2337297_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 0.00000000000000000000175 94.0
HFD1_k127_233940_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000004894 220.0
HFD1_k127_233940_1 YCII-related domain - - - 0.00000000000000000000000000000000000000000000002326 171.0
HFD1_k127_233940_2 methyltransferase activity - - - 0.00007244 48.0
HFD1_k127_2340515_0 Thiamine pyrophosphate enzyme, central domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009134 517.0
HFD1_k127_2340515_1 Glutathione S-Transferase K11208 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0015036,GO:0016491,GO:0016667,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000004044 199.0
HFD1_k127_2340515_2 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000002955 180.0
HFD1_k127_2340515_3 alcohol dehydrogenase K00004 - 1.1.1.303,1.1.1.4 0.0000000846 56.0
HFD1_k127_2340515_4 BetI-type transcriptional repressor, C-terminal - - - 0.000007562 48.0
HFD1_k127_2340697_0 Acyl-CoA dehydrogenase, middle domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 566.0
HFD1_k127_2340697_1 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 346.0
HFD1_k127_2340697_2 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 315.0
HFD1_k127_2340697_3 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000004061 149.0
HFD1_k127_2340697_4 Protein of unknown function (DUF3106) - - - 0.0000000000000000000000002327 111.0
HFD1_k127_2340697_5 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000005131 94.0
HFD1_k127_2345447_0 Bacterial alpha-L-rhamnosidase C-terminal domain K05989 - 3.2.1.40 3.445e-257 813.0
HFD1_k127_2345447_1 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 362.0
HFD1_k127_2345447_2 PFAM Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000002846 140.0
HFD1_k127_2349205_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 335.0
HFD1_k127_2349205_1 Yip1 domain - - - 0.000000000000000000000000000000000000000000006475 166.0
HFD1_k127_2357319_0 glycosyl transferase group 1 K08256 - 2.4.1.345 0.0000000000000000000000000000000000000000000000000000000002342 213.0
HFD1_k127_2357319_1 Major Facilitator - - - 0.00000000000000000216 98.0
HFD1_k127_2363965_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 636.0
HFD1_k127_2363965_1 secretion pathway protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 511.0
HFD1_k127_2363965_2 Putative SAM-dependent methyltransferase - - - 0.000000000000000000000000001296 119.0
HFD1_k127_2363965_3 Type II secretion system protein C K02452 - - 0.00000000000213 69.0
HFD1_k127_2378330_0 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 605.0
HFD1_k127_2378330_1 Carboxypeptidase K14677 - 3.5.1.14 0.000000000000000000000000000000000000000000001271 168.0
HFD1_k127_2378330_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000006103 175.0
HFD1_k127_2378330_3 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000009991 166.0
HFD1_k127_2381826_0 Cys Met metabolism K01739,K01758 - 2.5.1.48,4.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 520.0
HFD1_k127_2381826_1 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 509.0
HFD1_k127_2381826_2 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 408.0
HFD1_k127_2381826_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007932 238.0
HFD1_k127_2381826_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000001169 234.0
HFD1_k127_2381826_5 involved in sulfation activity towards typical ceramide glycolipids and trehalose glycolipids K01014 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006790,GO:0008146,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016782,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044272,GO:0044281,GO:0046505,GO:0046506,GO:0071704,GO:1901576 2.8.2.1 0.0000000000000000000000000000000000000000000000000000000001042 214.0
HFD1_k127_2381826_6 KR domain K00219 - 1.3.1.34 0.00000000000000000000000000000000000000000000000001839 192.0
HFD1_k127_2381826_7 - - - - 0.00000000000000000000000004825 115.0
HFD1_k127_2392339_0 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 613.0
HFD1_k127_2392339_1 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000008835 224.0
HFD1_k127_2392339_2 protein conserved in bacteria K09922 - - 0.000000000000000000000000000000000000000000000000000000002081 203.0
HFD1_k127_2403154_0 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 507.0
HFD1_k127_2403154_1 Transcriptional regulator, LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 448.0
HFD1_k127_2403154_2 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 381.0
HFD1_k127_2403154_3 MOSC domain containing protein K07140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008688 255.0
HFD1_k127_2403154_4 cellular response to lipid hydroperoxide K00799 GO:0000003,GO:0000323,GO:0001775,GO:0002237,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003006,GO:0003674,GO:0003824,GO:0004364,GO:0004601,GO:0004602,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005764,GO:0005765,GO:0005766,GO:0005773,GO:0005774,GO:0005777,GO:0005778,GO:0005783,GO:0005789,GO:0005886,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006805,GO:0006807,GO:0006810,GO:0006887,GO:0006950,GO:0006955,GO:0006979,GO:0006982,GO:0007275,GO:0007548,GO:0008150,GO:0008152,GO:0008406,GO:0008584,GO:0009058,GO:0009410,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009987,GO:0010033,GO:0010243,GO:0012505,GO:0012506,GO:0016020,GO:0016021,GO:0016043,GO:0016192,GO:0016209,GO:0016491,GO:0016684,GO:0016740,GO:0016765,GO:0019867,GO:0022414,GO:0022607,GO:0030141,GO:0030154,GO:0030659,GO:0030667,GO:0031090,GO:0031224,GO:0031410,GO:0031903,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0031982,GO:0031984,GO:0032496,GO:0032501,GO:0032502,GO:0032940,GO:0033194,GO:0033218,GO:0033327,GO:0033554,GO:0033993,GO:0034599,GO:0034641,GO:0035577,GO:0036230,GO:0042119,GO:0042175,GO:0042221,GO:0042277,GO:0042493,GO:0042579,GO:0042582,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043295,GO:0043299,GO:0043312,GO:0043603,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044272,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044432,GO:0044433,GO:0044437,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045137,GO:0045177,GO:0045321,GO:0046546,GO:0046661,GO:0046903,GO:0046983,GO:0048037,GO:0048513,GO:0048608,GO:0048731,GO:0048856,GO:0048869,GO:0050896,GO:0051179,GO:0051186,GO:0051234,GO:0051259,GO:0051260,GO:0051704,GO:0051707,GO:0051716,GO:0055114,GO:0061458,GO:0065003,GO:0070206,GO:0070207,GO:0070887,GO:0071447,GO:0071449,GO:0071466,GO:0071704,GO:0071840,GO:0071944,GO:0072341,GO:0097237,GO:0097708,GO:0098588,GO:0098754,GO:0098805,GO:0098827,GO:0098852,GO:0098869,GO:0099503,GO:1900750,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1901685,GO:1901687,GO:1901698,GO:1901700,GO:1901701,GO:1990748 2.5.1.18 0.00000000000000000005873 95.0
HFD1_k127_2405480_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1200.0
HFD1_k127_2405480_1 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000959 502.0
HFD1_k127_2405480_2 Methionine synthase K00549,K22363 - 2.1.1.14,4.4.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 422.0
HFD1_k127_2405480_3 COG1943 Transposase and inactivated derivatives K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002665 284.0
HFD1_k127_2405480_4 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 0.00000000000000000000000000000000008773 154.0
HFD1_k127_2405480_5 Transcriptional K06075 - - 0.00000000000000000000000000000254 130.0
HFD1_k127_2405480_6 flavin reductase - - - 0.0000000000000000000000000000502 120.0
HFD1_k127_240698_0 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 464.0
HFD1_k127_240698_1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006916 462.0
HFD1_k127_240698_2 Protein of unknown function (DUF2783) - - - 0.00000000000007421 76.0
HFD1_k127_240698_3 dioxygenase activity K00477 - 1.14.11.18 0.000000000000157 82.0
HFD1_k127_2412512_0 Alpha-2-Macroglobulin K06894 - - 2.253e-301 954.0
HFD1_k127_2432462_0 Belongs to the peptidase S16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 559.0
HFD1_k127_2432462_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 456.0
HFD1_k127_2432462_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 417.0
HFD1_k127_2432462_3 PFAM pyridoxamine 5'-phosphate - - - 0.00000001992 63.0
HFD1_k127_2440914_0 Fumarate reductase flavoprotein C-term K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 7.26e-317 976.0
HFD1_k127_2440914_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 5.324e-236 742.0
HFD1_k127_2440914_10 COG0568 DNA-directed RNA polymerase, sigma subunit K03087 GO:0000988,GO:0000990,GO:0001000,GO:0001121,GO:0001123,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.00007211 49.0
HFD1_k127_2440914_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.495e-228 714.0
HFD1_k127_2440914_3 Selenocysteine synthase N terminal K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 442.0
HFD1_k127_2440914_4 NADP oxidoreductase coenzyme F420-dependent K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 389.0
HFD1_k127_2440914_5 Elongation factor SelB, winged helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009327 309.0
HFD1_k127_2440914_6 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000002166 235.0
HFD1_k127_2440914_7 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000004138 174.0
HFD1_k127_2440914_8 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000004595 139.0
HFD1_k127_2440914_9 Succinate dehydrogenase hydrophobic membrane anchor subunit K00242 - - 0.00000000000000000000000008019 116.0
HFD1_k127_2443718_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 1072.0
HFD1_k127_2443718_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 438.0
HFD1_k127_2443718_2 PLD-like domain K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 351.0
HFD1_k127_2443718_3 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000002342 237.0
HFD1_k127_2443718_4 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000000000000000000000000000000000001184 161.0
HFD1_k127_2451390_0 COG2211 Na melibiose symporter and related transporters K03292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 390.0
HFD1_k127_2451390_1 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006684 370.0
HFD1_k127_2451390_2 polyphosphate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 369.0
HFD1_k127_2451390_3 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 327.0
HFD1_k127_2451390_4 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009278 264.0
HFD1_k127_2451390_5 - - - - 0.0000001698 57.0
HFD1_k127_2463010_0 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 374.0
HFD1_k127_2463010_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000004601 81.0
HFD1_k127_2463010_2 Protein conserved in bacteria - - - 0.00000000001001 66.0
HFD1_k127_247403_0 Berberine and berberine like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006124 546.0
HFD1_k127_247403_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 407.0
HFD1_k127_247403_10 GCN5-related N-acetyl-transferase - - - 0.00000000000000000000000002167 116.0
HFD1_k127_247403_12 COG0695 Glutaredoxin and related proteins - - - 0.000000001637 60.0
HFD1_k127_247403_13 - - - - 0.0000229 48.0
HFD1_k127_247403_2 Alpha beta hydrolase K22318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 365.0
HFD1_k127_247403_3 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 371.0
HFD1_k127_247403_4 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000002203 251.0
HFD1_k127_247403_5 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000001402 250.0
HFD1_k127_247403_6 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000005784 234.0
HFD1_k127_247403_7 Glutathione S-transferase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000009749 209.0
HFD1_k127_247403_8 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 0.00000000000000000000000000000000000000000000578 165.0
HFD1_k127_247403_9 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K14055 GO:0000302,GO:0001539,GO:0006928,GO:0006950,GO:0006979,GO:0008150,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0033554,GO:0034599,GO:0034614,GO:0034644,GO:0035690,GO:0040011,GO:0042221,GO:0042493,GO:0042542,GO:0042710,GO:0044010,GO:0044764,GO:0046677,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071478,GO:0071482,GO:0071973,GO:0097237,GO:0097588,GO:0104004,GO:1901700,GO:1901701 - 0.0000000000000000000000000000001692 137.0
HFD1_k127_2480409_0 Periplasmic binding proteins and sugar binding domain of LacI family K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 330.0
HFD1_k127_2480409_1 Oxidoreductase family, C-terminal alpha beta domain K16043 - 1.1.1.370 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001593 291.0
HFD1_k127_2480409_2 - - - - 0.0000000000000000000000000000000004661 141.0
HFD1_k127_2480409_3 Belongs to the binding-protein-dependent transport system permease family K10440 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015591,GO:0015749,GO:0015750,GO:0015752,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034219,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000003152 100.0
HFD1_k127_2487147_0 PFAM glycosyl transferase family 35 K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 537.0
HFD1_k127_2487147_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 488.0
HFD1_k127_2487147_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 411.0
HFD1_k127_2487805_0 Protein of unknown function (DUF3604) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 535.0
HFD1_k127_2501489_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.11.2 2.234e-243 770.0
HFD1_k127_2508967_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 361.0
HFD1_k127_2508967_1 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.00000000000000000000000000000000000001626 156.0
HFD1_k127_2508967_2 PFAM VanZ - - - 0.0004972 52.0
HFD1_k127_2514169_0 PFAM Orn DAP Arg decarboxylase 2 K01585 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 607.0
HFD1_k127_2514169_1 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 424.0
HFD1_k127_2514169_10 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K03741 - 1.20.4.1,3.1.3.48 0.000000000000000000005626 105.0
HFD1_k127_2514169_12 - - - - 0.000000000000002193 84.0
HFD1_k127_2514169_13 4 iron, 4 sulfur cluster binding - - - 0.000000008282 57.0
HFD1_k127_2514169_2 EcsC protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005615 259.0
HFD1_k127_2514169_3 Belongs to the UPF0178 family K09768 - - 0.00000000000000000000000000000000000000000000000000000007968 202.0
HFD1_k127_2514169_4 G T U mismatch-specific DNA glycosylase - - - 0.00000000000000000000000000000000000000000000001415 180.0
HFD1_k127_2514169_5 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000001057 163.0
HFD1_k127_2514169_6 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000007894 156.0
HFD1_k127_2514169_7 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.000000000000000000000000001002 115.0
HFD1_k127_2514169_8 NUDIX domain - - - 0.000000000000000000000000004047 117.0
HFD1_k127_252009_0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00123 - 1.17.1.9 2.36e-248 774.0
HFD1_k127_252009_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000005776 218.0
HFD1_k127_2520850_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1058.0
HFD1_k127_2520850_1 acetyl-coa acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 591.0
HFD1_k127_2520850_10 Protein of unknown function (DUF3313) - - - 0.00000000000000000000000000000000000000000003138 170.0
HFD1_k127_2520850_11 subfamily IA, variant 3 K20881 - 3.1.3.5 0.00000000000000000000000001189 113.0
HFD1_k127_2520850_12 - - - - 0.0000000000001741 78.0
HFD1_k127_2520850_13 Protein of unknown function (DUF2799) - - - 0.00000000006084 70.0
HFD1_k127_2520850_2 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 550.0
HFD1_k127_2520850_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 520.0
HFD1_k127_2520850_4 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 370.0
HFD1_k127_2520850_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 298.0
HFD1_k127_2520850_6 3'(2'),5'-bisphosphate nucleotidase K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001631 273.0
HFD1_k127_2520850_7 Acyl-CoA dehydrogenase, C-terminal domain K16047 - 1.14.14.12 0.00000000000000000000000000000000000000000000000000000000000000000002931 247.0
HFD1_k127_2520850_8 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000000000000000000000000000000000000002204 220.0
HFD1_k127_2520850_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K21137 - - 0.0000000000000000000000000000000000000000000000000000000000001384 228.0
HFD1_k127_2521071_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K07303 - 1.3.99.16 1.938e-237 762.0
HFD1_k127_2521071_1 Xylose isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000005122 241.0
HFD1_k127_2521071_2 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS - - - 0.000000000000000000000000000000000000000000000000000000000000004397 220.0
HFD1_k127_2524544_0 chemotaxis protein K02660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 494.0
HFD1_k127_2524544_1 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 408.0
HFD1_k127_2524544_2 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001474 248.0
HFD1_k127_2524544_3 response regulator K02657 - - 0.0000000000000000000000000000000000000000000000000000000000000269 216.0
HFD1_k127_2524544_4 Belongs to the UPF0301 (AlgH) family K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000003344 204.0
HFD1_k127_2524544_5 Response regulator receiver K02658 - - 0.000000000000000000000000000000000000000000000000001297 186.0
HFD1_k127_2524544_6 chemotaxis signal transduction protein K02659 - - 0.0000000000000000000000000000000000000000348 159.0
HFD1_k127_2524544_7 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.000000000000000000000000000000000000578 145.0
HFD1_k127_2524544_8 Signal transducing histidine kinase, homodimeric domain K02487,K06596 - - 0.00000000000002253 74.0
HFD1_k127_2544865_0 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 546.0
HFD1_k127_2544865_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009384 464.0
HFD1_k127_2544865_2 efflux protein, MATE family K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 349.0
HFD1_k127_2544865_3 COG0655 Multimeric flavodoxin WrbA - - - 0.00000000000000000000000000000000000000000000000000001863 192.0
HFD1_k127_2544865_4 mechanosensitive ion channel activity K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.000000000000000000000000000000000000000000000000001027 185.0
HFD1_k127_2544865_5 Protein of unknown function (DUF3014) - - - 0.000000000000000000000000000000006948 137.0
HFD1_k127_2544865_6 PFAM tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000008451 100.0
HFD1_k127_2544865_7 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000001583 68.0
HFD1_k127_2553017_0 Enoyl-CoA hydratase/isomerase - - - 2.343e-221 700.0
HFD1_k127_2553017_1 Sulfatase - - - 1.697e-213 674.0
HFD1_k127_2553017_2 Domain of unknown function (DUF1971) - - - 0.000000000000000000000000000000000006912 138.0
HFD1_k127_2553017_3 Phytanoyl-CoA dioxygenase (PhyH) K21195 - 1.14.11.46 0.0000000000000000000000000000006457 123.0
HFD1_k127_2567921_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 376.0
HFD1_k127_2567921_1 Putative thioesterase (yiiD_Cterm) - GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 - 0.00000000000000000000000000001315 124.0
HFD1_k127_2567921_2 Amidase K01426 - 3.5.1.4 0.0000000000000000000000005476 106.0
HFD1_k127_2575591_0 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 481.0
HFD1_k127_2575591_1 Mitochondrial fission ELM1 K07276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 318.0
HFD1_k127_2575591_2 lipid kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000001205 237.0
HFD1_k127_2575591_3 PFAM NAD dependent epimerase dehydratase family K01710,K01784 - 4.2.1.46,5.1.3.2 0.00000000000000000000000000000000000001008 168.0
HFD1_k127_257732_0 poly(R)-hydroxyalkanoic acid synthase K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 481.0
HFD1_k127_2583833_0 von Willebrand factor, type A K11912 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005153 454.0
HFD1_k127_2583833_1 - - - - 0.000000000000000000000000000001943 131.0
HFD1_k127_2583833_2 PFAM PspA IM30 - - - 0.0000008305 54.0
HFD1_k127_2596165_0 Phenylacetate-CoA oxygenase, PaaI subunit K02611 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 323.0
HFD1_k127_2596165_1 metal-sulfur cluster biosynthetic enzyme K02612 GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000001703 206.0
HFD1_k127_2596165_2 Phenylacetic acid degradation B K02610 - - 0.00000000000000000000000000000000000000002009 160.0
HFD1_k127_2596165_3 Phenylacetic acid catabolic protein K02609 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.14.13.149 0.00000000000000000000000000000000000000002046 154.0
HFD1_k127_2596165_4 Oxidoreductase FAD-binding domain K02613 - - 0.000000000000001057 79.0
HFD1_k127_2602665_0 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 531.0
HFD1_k127_2602665_1 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 305.0
HFD1_k127_2602665_2 pilus assembly protein PilN K02663 - - 0.0000000000000000000000000000000000000000000000000000003611 198.0
HFD1_k127_2610905_0 COG0277 FAD FMN-containing dehydrogenases K00803 - 2.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009634 541.0
HFD1_k127_2610905_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 469.0
HFD1_k127_2610905_2 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000000000000000000000000001289 170.0
HFD1_k127_261996_0 alcohol dehydrogenase (NAD) activity K00001,K00121,K02267,K13980,K18857 GO:0000302,GO:0001101,GO:0001666,GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006970,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009410,GO:0009413,GO:0009414,GO:0009415,GO:0009628,GO:0009636,GO:0009651,GO:0009719,GO:0009725,GO:0009737,GO:0009743,GO:0009744,GO:0010033,GO:0010035,GO:0010038,GO:0010243,GO:0014070,GO:0014074,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0031000,GO:0032355,GO:0033993,GO:0034285,GO:0036270,GO:0036293,GO:0042221,GO:0042493,GO:0042542,GO:0042802,GO:0042803,GO:0043279,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046686,GO:0046983,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0055114,GO:0065007,GO:0070482,GO:0071944,GO:0080134,GO:0080135,GO:0097305,GO:1900037,GO:1900039,GO:1901698,GO:1901700 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 544.0
HFD1_k127_261996_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 527.0
HFD1_k127_261996_2 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 385.0
HFD1_k127_261996_3 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000001248 117.0
HFD1_k127_2641105_0 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008289,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031406,GO:0031975,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042277,GO:0042546,GO:0042597,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071723,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 353.0
HFD1_k127_2641105_1 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003572 281.0
HFD1_k127_2641105_2 Thiol disulfide interchange protein K03673 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000002275 129.0
HFD1_k127_2641105_3 Staphylococcal nuclease homologues - - - 0.0000000000000000001496 101.0
HFD1_k127_2641105_4 COG0695 Glutaredoxin and related proteins - - - 0.000000000000000003213 89.0
HFD1_k127_2644841_0 Efflux pump membrane transporter K03296,K18138 - - 1.716e-314 1001.0
HFD1_k127_2644841_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 409.0
HFD1_k127_2644841_2 Belongs to the glutaminase family K01425 - 3.5.1.2 0.0000000000000000000000000000000006203 130.0
HFD1_k127_2645383_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 589.0
HFD1_k127_2645383_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 475.0
HFD1_k127_2651022_0 - - - - 3.985e-198 622.0
HFD1_k127_2651022_1 Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane K11941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 422.0
HFD1_k127_2651022_2 Biotin carboxylase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 392.0
HFD1_k127_2651022_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001899 270.0
HFD1_k127_2651022_4 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001269 258.0
HFD1_k127_2651022_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000000006546 150.0
HFD1_k127_2651022_6 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000005549 145.0
HFD1_k127_2651022_7 - - - - 0.00000000000000000000000000000000125 144.0
HFD1_k127_2651022_8 Putative lumazine-binding - - - 0.0000000000000000000000001528 123.0
HFD1_k127_2651022_9 CAAX protease self-immunity - - - 0.000000000000000000000007285 111.0
HFD1_k127_2651726_0 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 331.0
HFD1_k127_2651726_1 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005183 279.0
HFD1_k127_2651726_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000005006 195.0
HFD1_k127_2651726_3 Short-chain dehydrogenase reductase sdr K00059,K03366 - 1.1.1.100,1.1.1.304,1.1.1.76 0.0000000000000000000000000000000000000000000000003957 186.0
HFD1_k127_2653103_0 Aldehyde oxidase and xanthine dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 561.0
HFD1_k127_2653103_1 Flavin-binding monooxygenase-like K03379 - 1.14.13.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003322 491.0
HFD1_k127_2653103_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 407.0
HFD1_k127_2653103_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000001858 149.0
HFD1_k127_2653103_4 stress protein (general stress protein 26) - - - 0.00000000000000000000000002878 113.0
HFD1_k127_2653103_5 ThiS family K03636 - - 0.000000000000000001707 87.0
HFD1_k127_2660484_0 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 371.0
HFD1_k127_2660484_1 Homoserine dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002379 233.0
HFD1_k127_2665355_0 protein conserved in bacteria K09760 GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000003712 225.0
HFD1_k127_2665355_1 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000124 136.0
HFD1_k127_2672455_0 HlyD family secretion protein K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 299.0
HFD1_k127_2672455_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000425 248.0
HFD1_k127_2672455_2 Domain of unknown function (DUF4281) - - - 0.000000000000000000000000000000000002981 145.0
HFD1_k127_2672455_3 Transcriptional regulator - - - 0.00000000000000000000000000000000005014 150.0
HFD1_k127_2672455_4 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000000434 99.0
HFD1_k127_2678035_0 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 354.0
HFD1_k127_2678035_1 Short-chain dehydrogenase reductase sdr K00038 - 1.1.1.53 0.000000000000000000000000000000000000000000000000000000000000000000001295 244.0
HFD1_k127_2678035_2 DTW K05812 - - 0.0000000000000000000000000000000000000000000000000001395 194.0
HFD1_k127_2678035_3 HutD K09975 - - 0.00000000000000000000004477 107.0
HFD1_k127_2678035_4 - - - - 0.000000000000000000002107 106.0
HFD1_k127_2678035_5 regulation of single-species biofilm formation - GO:0008150,GO:0043900,GO:0050789,GO:0050794,GO:0065007,GO:1900190 - 0.000000000000000000005403 99.0
HFD1_k127_2689412_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003851 250.0
HFD1_k127_2689412_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000607 207.0
HFD1_k127_2689412_2 lactoylglutathione lyase activity - - - 0.000000000000000000000001221 111.0
HFD1_k127_2689412_3 SnoaL-like domain - - - 0.000000000000000000002186 100.0
HFD1_k127_2689412_4 Peptidoglycan-binding domain 1 protein - - - 0.0000000002816 67.0
HFD1_k127_2690568_0 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 327.0
HFD1_k127_2690568_1 Bacterial transcription activator, effector binding domain K13652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001573 291.0
HFD1_k127_2690568_2 aminopeptidase K01263 - 3.4.11.14 0.000000000000000000000000000000000000000000000000000000003453 215.0
HFD1_k127_2700328_0 HflC and HflK could encode or regulate a protease K04088 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 402.0
HFD1_k127_2700328_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 303.0
HFD1_k127_271038_0 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 526.0
HFD1_k127_271038_1 Histidine kinase K07675 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 366.0
HFD1_k127_271038_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008754 276.0
HFD1_k127_271386_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009987,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019058,GO:0019068,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0044183,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0097159,GO:0097367,GO:0101031,GO:1901265,GO:1901363,GO:1990220 - 1.3e-275 856.0
HFD1_k127_271386_1 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 512.0
HFD1_k127_271386_10 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000682 96.0
HFD1_k127_271386_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 492.0
HFD1_k127_271386_3 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 303.0
HFD1_k127_271386_4 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 284.0
HFD1_k127_271386_5 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000004519 172.0
HFD1_k127_271386_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000000002589 162.0
HFD1_k127_271386_7 adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000002 158.0
HFD1_k127_271386_8 Methyltransferase K07443 - - 0.00000000000000000000000000000001147 130.0
HFD1_k127_271386_9 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000846 117.0
HFD1_k127_2714115_0 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005301 249.0
HFD1_k127_2714115_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001026 240.0
HFD1_k127_2714115_2 Glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000000000000000000000000000000000000000000000007895 226.0
HFD1_k127_2714115_3 methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000001087 192.0
HFD1_k127_2714115_4 GrpB protein - - - 0.000000000000000000000000000000252 134.0
HFD1_k127_2714115_5 aminoglycoside hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.00000000000000000000000000007429 127.0
HFD1_k127_2729354_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 2.468e-295 921.0
HFD1_k127_2733715_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 368.0
HFD1_k127_2733715_1 Belongs to the peptidase S1C family K04691,K04771,K04772 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006355 303.0
HFD1_k127_2738643_0 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002361 275.0
HFD1_k127_2738643_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000001162 184.0
HFD1_k127_2738643_2 PFAM NmrA-like family - - - 0.000000000000000000000000000000000000002501 158.0
HFD1_k127_2738643_3 mucin-desulfating sulfatase - - - 0.0000000000000000000000000000000003531 138.0
HFD1_k127_2738643_4 - - - - 0.000000000000000000000000000001097 124.0
HFD1_k127_2738643_5 Protein of unknown function (DUF2970) - - - 0.0000000000002637 81.0
HFD1_k127_2751385_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 422.0
HFD1_k127_2751385_1 Beta-lactamase K01286 - 3.4.16.4 0.00000000000000000002189 105.0
HFD1_k127_2764365_0 sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 434.0
HFD1_k127_2764365_1 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007504 260.0
HFD1_k127_2764365_2 Predicted integral membrane protein (DUF2282) - - - 0.000000001414 66.0
HFD1_k127_2768747_0 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008798 529.0
HFD1_k127_2768747_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 301.0
HFD1_k127_2768747_2 O-methyltransferase K00588 - 2.1.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002137 279.0
HFD1_k127_2768747_3 COG4240 Predicted kinase K15918 - 2.7.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000134 247.0
HFD1_k127_2768747_4 Signal transduction histidine kinase K07637 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010350,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000002281 236.0
HFD1_k127_2768747_5 Outer membrane lipoprotein - - - 0.00000000000000000000000005171 113.0
HFD1_k127_2768747_6 peptidase - - - 0.000003982 53.0
HFD1_k127_2769408_0 COG0138 AICAR transformylase IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) K00602 GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 8.442e-213 675.0
HFD1_k127_2769408_1 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 585.0
HFD1_k127_2769408_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 GO:0002943,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050896,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 332.0
HFD1_k127_2769408_3 zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000007454 169.0
HFD1_k127_2769408_4 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters K03557 - - 0.0000000000000000000003887 102.0
HFD1_k127_2769408_5 Cyclic nucleotide-monophosphate binding domain - - - 0.00001511 54.0
HFD1_k127_2774663_0 3-beta hydroxysteroid dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 477.0
HFD1_k127_2774663_1 Belongs to the peptidase S16 family - - - 0.00000000000000000000000000000003238 128.0
HFD1_k127_2774663_2 UbiA prenyltransferase family - - - 0.0000000000000000000001298 109.0
HFD1_k127_2790289_0 2-methylcitrate dehydratase K01720 - 4.2.1.79 2.475e-229 715.0
HFD1_k127_2790289_1 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 1.01e-206 650.0
HFD1_k127_2790289_2 Belongs to the malate synthase family K01638 GO:0003674,GO:0003824,GO:0004474,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044424,GO:0044464,GO:0046487,GO:0046912,GO:0071704 2.3.3.9 0.0000000000000000000000000000000000000000000000000000000000000005514 222.0
HFD1_k127_2790289_3 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.000000000000000000000000000000000000000000000000000000000001043 215.0
HFD1_k127_2803853_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 6.044e-217 682.0
HFD1_k127_2803853_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 373.0
HFD1_k127_2803853_2 Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives K11754 GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 322.0
HFD1_k127_2803853_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 301.0
HFD1_k127_2803853_4 membrane protein, required for colicin V production K03558 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 - 0.00000000000000000000000000001948 123.0
HFD1_k127_2803853_5 Sporulation related domain - - - 0.00000003577 62.0
HFD1_k127_2818947_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1111.0
HFD1_k127_2818947_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.00000000000000000000000000000000000449 143.0
HFD1_k127_284126_0 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 467.0
HFD1_k127_284126_1 Oxidoreductase family, NAD-binding Rossmann fold K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000000000018 125.0
HFD1_k127_284126_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00004456 48.0
HFD1_k127_2842437_0 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 528.0
HFD1_k127_2842437_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 372.0
HFD1_k127_2842437_2 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 300.0
HFD1_k127_2842437_3 Methyltransferase - - - 0.000000000000000000001058 95.0
HFD1_k127_2842437_4 SMP-30/Gluconolaconase/LRE-like region - - - 0.0000008409 59.0
HFD1_k127_2843125_0 DinB superfamily - - - 2.886e-202 636.0
HFD1_k127_2843125_1 Histidine-specific methyltransferase, SAM-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 444.0
HFD1_k127_2843125_2 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 376.0
HFD1_k127_2843125_3 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000008102 234.0
HFD1_k127_2843125_4 Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family K00561 - 2.1.1.184 0.00000000000000000000000000000000000001597 154.0
HFD1_k127_2843125_5 Major facilitator Superfamily - - - 0.0000000000000003276 84.0
HFD1_k127_2853137_0 Peptidase family M1 domain K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005556 513.0
HFD1_k127_2858113_0 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 334.0
HFD1_k127_2858113_1 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000001816 258.0
HFD1_k127_2858113_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000001959 154.0
HFD1_k127_2858113_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000001201 125.0
HFD1_k127_2867329_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 398.0
HFD1_k127_2867329_1 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 387.0
HFD1_k127_2867329_2 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000705 138.0
HFD1_k127_2867329_3 Methyltransferase domain - - - 0.0000000000000001982 81.0
HFD1_k127_2872753_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 402.0
HFD1_k127_2872753_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000003157 159.0
HFD1_k127_2872753_2 Class II Aldolase and Adducin N-terminal domain - - - 0.00006446 47.0
HFD1_k127_2875099_0 Enoyl-CoA hydratase/isomerase K00626,K01692,K08299 - 2.3.1.9,4.2.1.149,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 298.0
HFD1_k127_2875099_1 Thiolase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000826 299.0
HFD1_k127_2875099_2 KR domain K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007021 293.0
HFD1_k127_2875099_3 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.0000000000000000000000273 106.0
HFD1_k127_2875099_4 BetI-type transcriptional repressor, C-terminal - - - 0.00000000000000000001772 99.0
HFD1_k127_2882211_0 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 349.0
HFD1_k127_2882211_1 Pyridoxamine 5'-phosphate K07006 - - 0.000000000000000000000000000000000000000000000000000000000000001948 220.0
HFD1_k127_2882211_2 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000003723 227.0
HFD1_k127_2882211_3 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000002114 130.0
HFD1_k127_2882211_4 TIGRFAM phasin family protein - - - 0.00000000000000000003905 95.0
HFD1_k127_2883942_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 360.0
HFD1_k127_2883942_1 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 294.0
HFD1_k127_2883942_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000875 306.0
HFD1_k127_2883942_3 COG0583 Transcriptional regulator K03566 - - 0.00001102 49.0
HFD1_k127_2887269_0 Phospholipase D. Active site motifs. K06132 - - 2.527e-222 701.0
HFD1_k127_2887269_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 349.0
HFD1_k127_2887269_2 - - - - 0.00000000000000000000000000000000106 138.0
HFD1_k127_2887269_3 Family of unknown function (DUF5329) - - - 0.0000000000000000000000000001536 119.0
HFD1_k127_2887269_4 bacterial OsmY and nodulation domain K04065 - - 0.000006622 55.0
HFD1_k127_2892465_0 PFAM ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 490.0
HFD1_k127_2892465_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009878 463.0
HFD1_k127_2903339_0 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K10619 - 1.14.12.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001848 287.0
HFD1_k127_2903339_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000009687 175.0
HFD1_k127_2909799_0 COG3209 Rhs family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 449.0
HFD1_k127_2909799_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 378.0
HFD1_k127_2909799_2 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 340.0
HFD1_k127_2909799_3 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 317.0
HFD1_k127_2909799_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000003757 149.0
HFD1_k127_2909799_5 Transfers electrons from cytochrome c551 to cytochrome oxidase - - - 0.00000000000000000000000000000005287 142.0
HFD1_k127_2909799_6 - - - - 0.00000004278 58.0
HFD1_k127_2909799_7 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.00001221 48.0
HFD1_k127_2910960_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 7.745e-284 888.0
HFD1_k127_2910960_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 399.0
HFD1_k127_2910960_2 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 338.0
HFD1_k127_2910960_3 Part of a membrane complex involved in electron transport K03614 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000001015 247.0
HFD1_k127_2910960_4 Part of a membrane complex involved in electron transport K03616 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0055114 - 0.00000000000000000000000000000000000000000000000005048 195.0
HFD1_k127_2910960_5 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000008791 134.0
HFD1_k127_2910960_6 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000002403 88.0
HFD1_k127_2910960_7 Part of a membrane complex involved in electron transport K03613 - - 0.000000000003508 74.0
HFD1_k127_2910960_8 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000001396 73.0
HFD1_k127_2916912_0 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 1.758e-214 680.0
HFD1_k127_2916912_1 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000415 279.0
HFD1_k127_2916912_2 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007587 265.0
HFD1_k127_2916912_3 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000002868 183.0
HFD1_k127_2916912_4 PFAM Archease protein family (DUF101 UPF0211) K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000003501 171.0
HFD1_k127_2942797_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 7.645e-295 924.0
HFD1_k127_2942797_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008137,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0050136,GO:0051179,GO:0051234,GO:0051536,GO:0051539,GO:0051540,GO:0055085,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004919 348.0
HFD1_k127_2942797_2 NADH dehydrogenase K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000002135 243.0
HFD1_k127_2942797_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000008915 196.0
HFD1_k127_2942797_4 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000005701 175.0
HFD1_k127_2942797_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000000000001587 169.0
HFD1_k127_2942797_6 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000000000000002006 170.0
HFD1_k127_2942797_7 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000000000000004183 130.0
HFD1_k127_2942797_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000001437 76.0
HFD1_k127_2951862_0 cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003042 268.0
HFD1_k127_2951862_1 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007358 248.0
HFD1_k127_2951862_2 dihydrodipicolinate reductase - - - 0.00000000000000007096 86.0
HFD1_k127_2951862_3 Short-chain dehydrogenase reductase sdr K00038 - 1.1.1.53 0.00000000004609 71.0
HFD1_k127_2954737_0 acyl-CoA dehydrogenase - - - 5.145e-222 703.0
HFD1_k127_2954737_1 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 291.0
HFD1_k127_2954737_2 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000428 183.0
HFD1_k127_2954737_3 Competence protein - - - 0.000000000000000000000000000000000000000000006896 173.0
HFD1_k127_2954737_4 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.0000000000000000000000000000000000000005535 158.0
HFD1_k127_2963247_0 amidohydrolase - - - 7.588e-208 662.0
HFD1_k127_2963247_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 500.0
HFD1_k127_2963247_2 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000001342 116.0
HFD1_k127_2963247_3 - - - - 0.000000001678 63.0
HFD1_k127_2991031_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K18688 - 6.2.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 593.0
HFD1_k127_2991031_1 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 540.0
HFD1_k127_2991031_2 COG4235 Cytochrome c biogenesis factor K02200 - - 0.00000000001355 76.0
HFD1_k127_3016800_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 427.0
HFD1_k127_3016800_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001695 279.0
HFD1_k127_3016800_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001233 271.0
HFD1_k127_302508_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 460.0
HFD1_k127_302508_1 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 364.0
HFD1_k127_302508_2 DNA ligase (ATP) activity K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 296.0
HFD1_k127_302508_3 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form - - - 0.0000000000000000000000000000000003697 134.0
HFD1_k127_302508_4 - - - - 0.0006163 49.0
HFD1_k127_3049920_0 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 330.0
HFD1_k127_3049920_1 Enoyl-CoA hydratase/isomerase K18383 - 4.1.2.41,4.2.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004844 282.0
HFD1_k127_3049920_2 2-hydroxychromene-2-carboxylate isomerase K14584 - 5.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000005597 266.0
HFD1_k127_3049920_3 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000009213 241.0
HFD1_k127_3049920_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000232 194.0
HFD1_k127_3049920_5 PFAM FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000001047 167.0
HFD1_k127_3049920_6 Transcriptional regulator - - - 0.00000000000000000000000000000000000003636 148.0
HFD1_k127_3049920_7 Putative adhesin - - - 0.0000000000000000000000000000000006991 147.0
HFD1_k127_3049920_8 KR domain - - - 0.0000000000001004 77.0
HFD1_k127_3049920_9 - - - - 0.0000002452 61.0
HFD1_k127_3049972_0 Belongs to the heat shock protein 70 family K04046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 520.0
HFD1_k127_3049972_1 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 409.0
HFD1_k127_3049972_2 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000397 207.0
HFD1_k127_3049972_3 NUDIX domain - - - 0.0000000000000000000000000000000000001161 149.0
HFD1_k127_3049972_4 PFAM thioesterase superfamily - - - 0.00000000000000000000000000009902 120.0
HFD1_k127_3049972_5 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000001579 81.0
HFD1_k127_3057630_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K21726 - 1.14.13.166,1.14.13.29,1.14.14.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 310.0
HFD1_k127_3057630_1 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000154 259.0
HFD1_k127_3057630_2 PFAM Tetratricopeptide repeat K07126 - - 0.000000000000000000000000000001171 125.0
HFD1_k127_30683_0 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000009402 145.0
HFD1_k127_30683_1 Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function K15723 - - 0.000000000000000000000000000000726 125.0
HFD1_k127_30683_2 Heavy-metal resistance - - - 0.0000000001521 70.0
HFD1_k127_30683_3 EF-hand domain pair - - - 0.000006787 56.0
HFD1_k127_30683_5 Type II transport protein GspH K08084 - - 0.0002039 47.0
HFD1_k127_3077041_0 Protein synonym acyl-CoA synthetase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 569.0
HFD1_k127_3077041_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.0000000000000000000000000000000000000000000000000000000001733 205.0
HFD1_k127_3077041_2 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000000000002346 192.0
HFD1_k127_3077041_3 Protein of unknown function (DUF3187) - - - 0.0000000000000000000000000000000000000000001342 174.0
HFD1_k127_3077041_4 protein, possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000003432 153.0
HFD1_k127_3086719_0 metal-dependent hydrolase of the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007482 446.0
HFD1_k127_3086719_1 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001354 290.0
HFD1_k127_3086719_2 TIGRFAM alpha-L-glutamate ligase-like protein - - - 0.0000000000000000001933 90.0
HFD1_k127_3086719_3 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000003927 85.0
HFD1_k127_3089833_0 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005348 342.0
HFD1_k127_3089833_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005081 329.0
HFD1_k127_3089833_2 protein flavinylation K03734 - 2.7.1.180 0.0000000000006958 75.0
HFD1_k127_3103928_0 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008912 268.0
HFD1_k127_3103928_1 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000001527 192.0
HFD1_k127_313016_1 - - - - 0.0000000000000003164 82.0
HFD1_k127_3130968_0 Peptidase family S58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008205 410.0
HFD1_k127_3130968_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009293 249.0
HFD1_k127_3163772_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 9.785e-253 803.0
HFD1_k127_3163772_1 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 565.0
HFD1_k127_3163772_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 315.0
HFD1_k127_3163772_3 Domain of unknown function (DUF1956) - - - 0.0000000000000000000000000000000000000004148 160.0
HFD1_k127_3166951_0 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 506.0
HFD1_k127_3166951_1 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 381.0
HFD1_k127_3166951_2 UPF0126 domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000004965 235.0
HFD1_k127_3166951_3 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000000002278 211.0
HFD1_k127_3166951_4 Lysine methyltransferase K00564 - 2.1.1.172 0.0000000000000000000000000000000000000000000000000000002909 198.0
HFD1_k127_3166951_5 SnoaL-like domain K06893 - - 0.000000000000000000000000000000000000000002274 158.0
HFD1_k127_3166951_6 Enoyl-CoA hydratase/isomerase - - - 0.0000000000002957 74.0
HFD1_k127_3190026_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1078.0
HFD1_k127_3190026_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051301,GO:0051704,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005431 516.0
HFD1_k127_3215516_0 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate - - - 0.0000000000000000000000000000000000000000000000001441 184.0
HFD1_k127_3215516_1 Activator of Hsp90 ATPase family protein 3 - - - 0.00000000000000000000000000000000000000000000004019 178.0
HFD1_k127_3215516_2 COG0346 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000003141 105.0
HFD1_k127_3215516_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000008686 96.0
HFD1_k127_3231757_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 322.0
HFD1_k127_3231757_1 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006498 294.0
HFD1_k127_3231757_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003628 273.0
HFD1_k127_3231757_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000001804 113.0
HFD1_k127_3232235_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 503.0
HFD1_k127_3232235_1 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001014 281.0
HFD1_k127_3232235_2 polysaccharide catabolic process K02388,K02396 - - 0.00001248 53.0
HFD1_k127_323521_0 ABC transporter transmembrane region K06147,K18890 - - 3.672e-225 721.0
HFD1_k127_323521_1 ABC transporter, transmembrane region K06147,K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 560.0
HFD1_k127_323521_2 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 417.0
HFD1_k127_3235977_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 3.771e-252 789.0
HFD1_k127_3235977_1 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 430.0
HFD1_k127_3235977_2 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000162 246.0
HFD1_k127_3235977_3 Asparaginase, N-terminal K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000001707 199.0
HFD1_k127_3235977_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000897 205.0
HFD1_k127_3235977_5 FR47-like protein K03829 - - 0.000000000000000000000000000000000132 146.0
HFD1_k127_3235977_6 Aminotransferase class I and II K16423 - 2.6.1.103 0.0001959 44.0
HFD1_k127_3238961_0 COG0183 Acetyl-CoA acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 532.0
HFD1_k127_3238961_1 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007809 481.0
HFD1_k127_3238961_10 Phosphoglycerate mutase family K08296 - - 0.000000000000000000000000000004026 126.0
HFD1_k127_3238961_11 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0010181,GO:0016491,GO:0016614,GO:0016899,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032553,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042803,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 0.000000000244 70.0
HFD1_k127_3238961_2 LysR substrate binding domain K03576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 420.0
HFD1_k127_3238961_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 346.0
HFD1_k127_3238961_4 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009832 291.0
HFD1_k127_3238961_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 285.0
HFD1_k127_3238961_6 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000803 275.0
HFD1_k127_3238961_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003211 245.0
HFD1_k127_3238961_9 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.0000000000000000000000000000000000000003355 166.0
HFD1_k127_3249126_0 GTP-binding protein TypA K06207 - - 3.936e-261 816.0
HFD1_k127_3249126_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 584.0
HFD1_k127_3249126_2 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 546.0
HFD1_k127_3249126_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 306.0
HFD1_k127_3249126_4 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000008872 166.0
HFD1_k127_3249126_5 highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues K01915 - 6.3.1.2 0.000000000000000000000000000003556 120.0
HFD1_k127_3249126_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000000000000000000009484 114.0
HFD1_k127_3249126_7 Phosphoribosyl-ATP pyrophosphohydrolase K01523 GO:0000105,GO:0003674,GO:0003824,GO:0004636,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.6.1.31 0.00000000000000000000000001413 126.0
HFD1_k127_3249126_8 sulfur carrier activity K04085 - - 0.0000000000000000000007388 100.0
HFD1_k127_3249126_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000001565 72.0
HFD1_k127_3250626_0 L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.12 1.644e-273 851.0
HFD1_k127_3250626_1 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000000000008245 187.0
HFD1_k127_3250626_2 Putative regulatory protein - - - 0.00000000000000000000000000002969 122.0
HFD1_k127_3250626_3 Bacterial DNA-binding protein - - - 0.00000000000000000000005482 104.0
HFD1_k127_3256076_0 2-oxoglutarate dehydrogenase complex K00382 - 1.8.1.4 2.138e-204 647.0
HFD1_k127_3256076_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903,K14067 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5,6.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 587.0
HFD1_k127_3256076_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 398.0
HFD1_k127_3263761_0 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.0 1331.0
HFD1_k127_3263761_1 Belongs to the UPF0276 family K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 384.0
HFD1_k127_3263761_2 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 309.0
HFD1_k127_3263761_3 Putative DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002824 255.0
HFD1_k127_3263761_4 DoxX K15977 - - 0.000000000000000000000000000000000000000000000000000000000009725 209.0
HFD1_k127_3263761_5 RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000009523 148.0
HFD1_k127_3263761_6 YHS domain - - - 0.00000000000000000000000000000000029 138.0
HFD1_k127_3263761_7 Putative zinc-finger - - - 0.0005459 51.0
HFD1_k127_3271308_0 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007946 488.0
HFD1_k127_3271308_1 Oxygenase, catalysing oxidative methylation of damaged DNA K09990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 351.0
HFD1_k127_3271308_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000003452 92.0
HFD1_k127_3272135_0 DNA polymerase alpha chain like domain K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 524.0
HFD1_k127_3272135_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000001179 224.0
HFD1_k127_3272135_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008194,GO:0008289,GO:0008610,GO:0008654,GO:0008915,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0019897,GO:0019898,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000001568 214.0
HFD1_k127_3276814_0 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 392.0
HFD1_k127_3276814_1 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.0000000000000000000000000000000000000000001162 168.0
HFD1_k127_3276979_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 325.0
HFD1_k127_329488_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01907 - 6.2.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 471.0
HFD1_k127_329488_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 336.0
HFD1_k127_329488_2 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00058 - 1.1.1.26,1.1.1.399,1.1.1.95 0.00000000003477 64.0
HFD1_k127_3304784_0 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 541.0
HFD1_k127_3304784_1 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000875 429.0
HFD1_k127_3304784_2 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000009414 90.0
HFD1_k127_3313390_0 Site-specific DNA-methyltransferase (Adenine-specific) K06223 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000001518 207.0
HFD1_k127_3313390_1 N-4 methylation of cytosine K00571 - 2.1.1.72 0.000000000000003052 79.0
HFD1_k127_3313390_2 Protein of unknown function (DUF4031) - - - 0.000000001121 63.0
HFD1_k127_3313390_3 - - - - 0.000000001686 69.0
HFD1_k127_3316613_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 596.0
HFD1_k127_3316613_1 ABC transporter ATP-binding protein K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 339.0
HFD1_k127_3316613_2 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008971 301.0
HFD1_k127_3316613_3 seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000001312 144.0
HFD1_k127_3316613_4 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - 0.0000000000000000000134 100.0
HFD1_k127_3316613_5 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA K11719 - - 0.0000000000009199 77.0
HFD1_k127_3316613_6 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.0000003093 52.0
HFD1_k127_3319061_0 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009899 469.0
HFD1_k127_3319061_1 permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 447.0
HFD1_k127_3319061_2 Transcriptional regulator, Crp Fnr family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009979 357.0
HFD1_k127_3319061_3 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000004212 157.0
HFD1_k127_3319061_4 Periplasmic or secreted lipoprotein - - - 0.0000000000000000000000000000008669 126.0
HFD1_k127_3319061_5 - - - - 0.0000000000000005485 78.0
HFD1_k127_3323791_0 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 406.0
HFD1_k127_3323791_1 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 346.0
HFD1_k127_3323791_2 taurine catabolism dioxygenase K03119,K22303 - 1.14.11.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005496 336.0
HFD1_k127_3323791_3 dihydrofolate reductase activity K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000001147 241.0
HFD1_k127_3323791_4 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000006831 177.0
HFD1_k127_3323791_5 glyoxalase III activity K16260 - - 0.000000000000000000000000000000000001212 143.0
HFD1_k127_3323791_6 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000001017 117.0
HFD1_k127_3323791_7 - - - - 0.000000000002827 75.0
HFD1_k127_3358294_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010876,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0030203,GO:0031224,GO:0031226,GO:0033036,GO:0034203,GO:0034204,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097035,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005689 483.0
HFD1_k127_3358294_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 459.0
HFD1_k127_3358294_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 429.0
HFD1_k127_3358294_3 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.0000000000000000000000000000005583 122.0
HFD1_k127_3358294_4 Binds directly to 16S ribosomal RNA K02968 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000004112 102.0
HFD1_k127_3358294_5 Belongs to the ribF family K11753 GO:0003674,GO:0003824,GO:0003919,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008531,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0044237,GO:0070566 2.7.1.26,2.7.7.2 0.00000000000141 68.0
HFD1_k127_3359566_0 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 504.0
HFD1_k127_3359566_1 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 439.0
HFD1_k127_3359566_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005769 267.0
HFD1_k127_3359566_3 MobA-like NTP transferase domain - - - 0.0000000000000000000000000000000000000000000000000001007 200.0
HFD1_k127_3359566_4 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000117 197.0
HFD1_k127_3360098_0 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000004805 209.0
HFD1_k127_3360098_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000009809 200.0
HFD1_k127_3360098_2 - - - - 0.000000000000000000000000000000001932 134.0
HFD1_k127_3360098_3 transcriptional regulator - - - 0.000000000000000000000000000000007608 130.0
HFD1_k127_3360098_4 amino acid K16263 - - 0.00000000000000000000000000000001141 135.0
HFD1_k127_3361074_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001241 229.0
HFD1_k127_3361074_1 Protein of unknown function (DUF456) K09793 - - 0.00000000000000000000000000000000000000000002101 170.0
HFD1_k127_3361074_2 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000006505 149.0
HFD1_k127_3361074_3 - - - - 0.0000000000000000000000000000000000002691 152.0
HFD1_k127_3361074_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000002083 96.0
HFD1_k127_3361074_5 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000003206 80.0
HFD1_k127_3361074_6 Methyltransferase domain - - - 0.00000000000006745 82.0
HFD1_k127_3361074_7 Domain of unknown function (DUF4345) - - - 0.00000003399 60.0
HFD1_k127_3361074_8 - - - - 0.00000098 53.0
HFD1_k127_3372023_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 450.0
HFD1_k127_3372023_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 328.0
HFD1_k127_3372023_2 COG2897 Rhodanese-related sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007774 310.0
HFD1_k127_3372023_3 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001302 249.0
HFD1_k127_3372023_4 Phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000005517 249.0
HFD1_k127_3372023_5 tRNA synthetases class II (D, K and N) K04568 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016746,GO:0016755,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052868,GO:0071704,GO:0071915,GO:0072580,GO:0072581,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000001462 162.0
HFD1_k127_337416_0 COG1199 Rad3-related DNA helicases K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009572 447.0
HFD1_k127_337416_1 VRR-NUC domain - - - 0.0000000003413 61.0
HFD1_k127_3391873_0 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 576.0
HFD1_k127_3391873_1 PFAM Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000002153 81.0
HFD1_k127_3405737_0 Lipoprotein releasing system transmembrane protein K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 331.0
HFD1_k127_3405737_1 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051234,GO:0051641,GO:0055085,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0097159,GO:0097367,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1990778 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006118 267.0
HFD1_k127_3408216_0 Aminotransferase class I and II K16423 - 2.6.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 490.0
HFD1_k127_3408216_1 hydrolase activity, acting on ester bonds K01259 - 3.4.11.5 0.00000000000000000006761 97.0
HFD1_k127_3410153_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 568.0
HFD1_k127_3410153_1 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 578.0
HFD1_k127_3410153_10 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000003648 130.0
HFD1_k127_3410153_11 DNA polymerase III subunit delta K02341 - 2.7.7.7 0.00000000000000000000000000000006033 138.0
HFD1_k127_3410153_12 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000000000845 106.0
HFD1_k127_3410153_13 metal-binding, possibly nucleic acid-binding protein K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000251 80.0
HFD1_k127_3410153_14 Splits dipeptides with a prolyl residue in the C- terminal position K01271 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.13.9 0.0004217 42.0
HFD1_k127_3410153_2 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 317.0
HFD1_k127_3410153_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0030497,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 314.0
HFD1_k127_3410153_4 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 299.0
HFD1_k127_3410153_5 TatD family K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000137 265.0
HFD1_k127_3410153_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000001363 246.0
HFD1_k127_3410153_7 Amino-transferase class IV K02619 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008696,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0019842,GO:0030170,GO:0034641,GO:0036094,GO:0042558,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000002729 227.0
HFD1_k127_3410153_8 pilus assembly protein, PilZ K02676 - - 0.00000000000000000000000000000000000000000000000000000002336 199.0
HFD1_k127_3410153_9 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000009866 178.0
HFD1_k127_3415045_0 Riboflavin kinase K11753 GO:0003674,GO:0003824,GO:0003919,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008531,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0044237,GO:0070566 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004511 283.0
HFD1_k127_3415045_1 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000002035 88.0
HFD1_k127_3421723_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 539.0
HFD1_k127_3421723_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 456.0
HFD1_k127_3421723_2 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity - - - 0.0000000000000000000000000000000000000000006872 164.0
HFD1_k127_3421723_3 N-terminal half of MaoC dehydratase K09709 - 4.2.1.153 0.00000000000000000000000000002954 127.0
HFD1_k127_3421723_4 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.000000000003587 68.0
HFD1_k127_3422418_0 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 373.0
HFD1_k127_3422418_1 COG0534 Na -driven multidrug efflux pump - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 337.0
HFD1_k127_3422418_2 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 310.0
HFD1_k127_3422418_3 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000502 217.0
HFD1_k127_3422418_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) - - - 0.000000000000000000000000000000000000000002525 161.0
HFD1_k127_3424871_0 SpoVR family K06415 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 9.786e-257 800.0
HFD1_k127_3424871_1 Belongs to the UPF0229 family K09786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 339.0
HFD1_k127_3424871_2 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 GO:0003674,GO:0003824,GO:0004652,GO:0004810,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0070566,GO:0071704,GO:0090304,GO:1901360,GO:1990817 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000002584 253.0
HFD1_k127_3426420_0 fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 362.0
HFD1_k127_3426420_1 Domain of Unknown Function (DUF349) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002575 276.0
HFD1_k127_3426420_2 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000004561 250.0
HFD1_k127_3426420_3 PaaX-like protein C-terminal domain K02616 - - 0.00002439 51.0
HFD1_k127_3429188_0 PFAM Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000004119 187.0
HFD1_k127_3429188_1 - - - - 0.0006629 48.0
HFD1_k127_3437593_0 penicillin-binding protein K05367 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 489.0
HFD1_k127_3437593_1 Alpha-2-Macroglobulin K06894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009918 274.0
HFD1_k127_3437945_0 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004982 288.0
HFD1_k127_3437945_1 And related - - - 0.00000000000000000000000000000000000000000000001401 181.0
HFD1_k127_3437945_2 sequence-specific DNA binding K03718 - - 0.00000000000000000008954 95.0
HFD1_k127_3437945_3 helix_turn_helix ASNC type K03718 - - 0.00000000000002935 81.0
HFD1_k127_3438898_0 PFAM Acyl-CoA dehydrogenase, type 2, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 392.0
HFD1_k127_3438898_1 Amidohydrolase K22213 - 4.1.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 347.0
HFD1_k127_3438898_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K11945,K16049 - 1.13.11.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008831 307.0
HFD1_k127_3438898_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000001674 216.0
HFD1_k127_3438898_4 Beta-lactamase - - - 0.00000000000000000000000000002167 122.0
HFD1_k127_3470588_0 cytochrome P-450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009732 554.0
HFD1_k127_3470588_1 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001844 259.0
HFD1_k127_3470588_2 Outer membrane protein beta-barrel domain - - - 0.000000000000000000005482 100.0
HFD1_k127_3470588_3 PRC-barrel domain - - - 0.00006316 54.0
HFD1_k127_347464_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004894 266.0
HFD1_k127_347464_1 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000003732 226.0
HFD1_k127_347464_2 Domain of unknown function (DUF1330) - - - 0.00000000000000000000004247 108.0
HFD1_k127_347674_0 ATP ADP translocase K03301 - - 0.00000000000000000000000000000000000000000000000009673 182.0
HFD1_k127_347674_2 Surface antigen - - - 0.0000000008648 70.0
HFD1_k127_3479730_0 P-aminobenzoate N-oxygenase AurF - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008507 452.0
HFD1_k127_3479730_1 protein histidine kinase activity K07716,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000001859 218.0
HFD1_k127_3479730_2 Glutamine amidotransferase domain K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000269 198.0
HFD1_k127_3479730_3 Ferredoxin K04755 - - 0.0000000000000000000000000000000000000001318 154.0
HFD1_k127_3485925_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 548.0
HFD1_k127_3485925_1 RNA polymerase sigma factor containing a TPR repeat domain K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 432.0
HFD1_k127_3485925_2 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 390.0
HFD1_k127_3485925_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 347.0
HFD1_k127_3485925_4 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 307.0
HFD1_k127_3485925_5 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002781 279.0
HFD1_k127_3485925_6 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000002014 191.0
HFD1_k127_3485925_7 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000001893 179.0
HFD1_k127_3485925_8 YCII-related domain - - - 0.000000000000000000000000000005506 123.0
HFD1_k127_3487818_0 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 306.0
HFD1_k127_3493917_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008301,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0030983,GO:0031323,GO:0032136,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - 5.377e-305 958.0
HFD1_k127_3493917_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000732 539.0
HFD1_k127_3493917_2 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000000001369 198.0
HFD1_k127_3493917_3 Modulates RecA activity K03565 - - 0.0000000000000000000000000000007146 127.0
HFD1_k127_3493917_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000009 108.0
HFD1_k127_3493917_5 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 0.00000000000000007992 81.0
HFD1_k127_3502158_0 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) K00059,K18335 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 404.0
HFD1_k127_3502158_1 Lanthionine synthetase C family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 293.0
HFD1_k127_3502158_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000001542 134.0
HFD1_k127_3502158_3 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000001372 117.0
HFD1_k127_3502158_4 - - - - 0.000000000000000000000000001511 127.0
HFD1_k127_3511362_0 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00004,K00008,K05351,K08322 - 1.1.1.14,1.1.1.303,1.1.1.380,1.1.1.4,1.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 383.0
HFD1_k127_3511362_1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 310.0
HFD1_k127_3511362_2 GYD domain - - - 0.00000000000000000000000000000001254 129.0
HFD1_k127_3511362_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000007259 110.0
HFD1_k127_3511362_4 hydrolase - - - 0.000000000000006692 81.0
HFD1_k127_3514844_0 Transglycosylase - - - 2.089e-284 902.0
HFD1_k127_3516531_0 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 2.96e-204 645.0
HFD1_k127_3516531_1 Biotin carboxylase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000001353 190.0
HFD1_k127_3517084_0 neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 368.0
HFD1_k127_3517084_1 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 320.0
HFD1_k127_3517084_2 Peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 336.0
HFD1_k127_3517084_3 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001225 281.0
HFD1_k127_3517084_4 Histidine kinase K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000001497 191.0
HFD1_k127_3518452_0 PFAM Prolyl oligopeptidase family - - - 3.659e-208 665.0
HFD1_k127_3518452_1 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000611 186.0
HFD1_k127_3518452_2 - - - - 0.000000000000000000000152 109.0
HFD1_k127_3523469_0 sister chromatid segregation - - - 0.0000000000000000000000000000000000000000000000000002897 195.0
HFD1_k127_3523469_1 cellulase activity - - - 0.00000000000000000000000000000000005096 147.0
HFD1_k127_3523469_2 cellulase activity - - - 0.00000000000000000000000119 112.0
HFD1_k127_3528062_0 Belongs to the glutaminase family K01425 - 3.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008528 454.0
HFD1_k127_3528062_1 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008808 333.0
HFD1_k127_3528062_2 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000007804 222.0
HFD1_k127_3528062_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000002534 111.0
HFD1_k127_3528062_4 Ion channel - - - 0.0000000000001169 83.0
HFD1_k127_3528062_5 Pfam:Pyridox_oxidase K07006 - - 0.0000001772 54.0
HFD1_k127_3532833_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 592.0
HFD1_k127_3532833_1 acyl-CoA dehydrogenase K22027 - 1.14.13.235 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 388.0
HFD1_k127_3532833_2 Nitroreductase family K04719 - 1.13.11.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000005333 262.0
HFD1_k127_3532833_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000007641 188.0
HFD1_k127_3532833_4 von Willebrand factor (vWF) type A domain - - - 0.00000000000000001494 89.0
HFD1_k127_3555260_0 glutamate dehydrogenase K15371 - 1.4.1.2 3.056e-298 938.0
HFD1_k127_356471_0 Required for chromosome condensation and partitioning K03529 - - 2.311e-194 634.0
HFD1_k127_356471_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 482.0
HFD1_k127_356471_2 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0022402,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032506,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - 0.0000000000000000000000000000000000000002026 161.0
HFD1_k127_3567388_0 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 7.821e-221 706.0
HFD1_k127_3567388_1 Ion channel - - - 0.0000000000000000000000000000000000000000000000000004015 188.0
HFD1_k127_3567388_2 Predicted metal-dependent hydrolase K07044 - - 0.00004337 46.0
HFD1_k127_3581614_0 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007073 318.0
HFD1_k127_3581614_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 312.0
HFD1_k127_3581614_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 307.0
HFD1_k127_3581614_3 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002587 226.0
HFD1_k127_3581614_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000003245 129.0
HFD1_k127_3581614_5 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000005559 122.0
HFD1_k127_3581614_6 SnoaL-like domain - - - 0.0000000000000008323 83.0
HFD1_k127_3600220_0 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 400.0
HFD1_k127_3600220_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 399.0
HFD1_k127_3600220_2 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 362.0
HFD1_k127_3600220_3 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 334.0
HFD1_k127_3600220_4 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 347.0
HFD1_k127_3600220_5 Belongs to the bacterial glucokinase family K00845 GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051156,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000001673 228.0
HFD1_k127_3600220_6 Polysaccharide biosynthesis protein K20946 - - 0.0000000000000000491 90.0
HFD1_k127_3604140_0 multicopper - - - 9.947e-202 640.0
HFD1_k127_3604140_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 391.0
HFD1_k127_3604140_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000001421 185.0
HFD1_k127_3606728_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 325.0
HFD1_k127_3606728_1 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002111 254.0
HFD1_k127_3606728_2 LysR substrate binding domain K03566,K17850 - - 0.00000000000000000000000000000000000000012 162.0
HFD1_k127_3606728_3 - - - - 0.000000000000000000000000000000000005882 150.0
HFD1_k127_3606728_4 - - - - 0.0000000000000001535 90.0
HFD1_k127_3608981_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 534.0
HFD1_k127_3608981_1 COG0451 Nucleoside-diphosphate-sugar epimerases K08679,K17947 - 5.1.3.25,5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008449 498.0
HFD1_k127_3608981_2 Type II secretory pathway, component ExeA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003871 261.0
HFD1_k127_3608981_3 AAA domain - - - 0.000000000000000000000000000000000000000000000000000004224 202.0
HFD1_k127_3608981_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 0.00000000000000000000001341 101.0
HFD1_k127_3608981_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000189 51.0
HFD1_k127_361182_0 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 331.0
HFD1_k127_361182_1 Bacterial transcriptional activator domain - - - 0.0003282 49.0
HFD1_k127_3621222_0 Amidohydrolase family - - - 3.409e-240 753.0
HFD1_k127_3621222_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 403.0
HFD1_k127_3649308_0 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 536.0
HFD1_k127_3649308_1 MFS/sugar transport protein K03292 - - 0.0000000000000000000000000000000000000000000000000000000379 211.0
HFD1_k127_3649308_2 F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000003447 201.0
HFD1_k127_3651964_0 (ABC) transporter K06148 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 515.0
HFD1_k127_3651964_1 Mitochondrial fission ELM1 K07276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009523 293.0
HFD1_k127_3651964_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.0000000000000000000002271 101.0
HFD1_k127_3651964_3 Acyl carrier protein - - - 0.000000007245 63.0
HFD1_k127_3651964_4 Permease, YjgP YjgQ family K07091 - - 0.0000008931 52.0
HFD1_k127_3651964_5 overlaps another CDS with the same product name K11720 - - 0.000004534 58.0
HFD1_k127_366901_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K02182,K13776 - 6.2.1.48 5.96e-226 715.0
HFD1_k127_366901_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 433.0
HFD1_k127_366901_2 MreB/Mbl protein K04046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 375.0
HFD1_k127_366901_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003548 289.0
HFD1_k127_366901_4 Belongs to the peptidase S16 family - - - 0.0000000000000004405 79.0
HFD1_k127_366901_5 Transglycosylase SLT domain - - - 0.000000001355 67.0
HFD1_k127_366901_7 12 heme-binding sites - - - 0.00000942 57.0
HFD1_k127_3669268_0 aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008479 497.0
HFD1_k127_3669268_1 And related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000339 265.0
HFD1_k127_3669268_2 PrcB C-terminal - - - 0.0001219 51.0
HFD1_k127_3677296_0 COG2211 Na melibiose symporter and related transporters K03292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 345.0
HFD1_k127_3677296_1 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000000000000004778 187.0
HFD1_k127_3694481_0 P-aminobenzoate N-oxygenase AurF - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 509.0
HFD1_k127_3694481_1 P-aminobenzoate N-oxygenase AurF - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 473.0
HFD1_k127_3694481_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003952 308.0
HFD1_k127_3694481_3 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001618 238.0
HFD1_k127_3694481_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000008304 92.0
HFD1_k127_3704581_0 Outer membrane receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000001101 228.0
HFD1_k127_3704581_1 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000001558 214.0
HFD1_k127_3704581_2 - - - - 0.0000000000000000000000000000000000000000000000000000409 193.0
HFD1_k127_3711595_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 587.0
HFD1_k127_3711595_1 AAA domain - - - 0.0000000000000000000000000000000000000000000000000001693 190.0
HFD1_k127_3711595_2 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000002498 162.0
HFD1_k127_3717998_0 PFAM Peptidoglycan-binding domain 1 protein K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 369.0
HFD1_k127_3717998_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 345.0
HFD1_k127_3717998_2 Dehydrogenase K17760 - 1.1.9.1 0.000000000000000000000000000000000000000000000003934 177.0
HFD1_k127_3717998_3 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000459 170.0
HFD1_k127_3717998_4 glycerophosphoryl diester phosphodiesterase - - - 0.00000000000000000000000000000000000000000239 179.0
HFD1_k127_3719112_0 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 3.927e-253 791.0
HFD1_k127_3719112_1 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 566.0
HFD1_k127_3719112_2 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 350.0
HFD1_k127_3719112_3 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0008442,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007667 311.0
HFD1_k127_3719112_4 Enoyl-CoA hydratase carnithine racemase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 318.0
HFD1_k127_3719112_5 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - 0.000000000000000000000000000000000000000000000000000000000002651 228.0
HFD1_k127_3719112_6 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - 0.0000000000000000000000000000000000000009046 162.0
HFD1_k127_3719112_7 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000008356 127.0
HFD1_k127_3719236_0 Enoyl-CoA hydratase isomerase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 367.0
HFD1_k127_3719236_1 Acetyltransferase (GNAT) domain K22479 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000031 285.0
HFD1_k127_3719236_2 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000001253 215.0
HFD1_k127_3719236_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.00000001397 59.0
HFD1_k127_3720095_0 glycosyl transferase family 8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 481.0
HFD1_k127_3720095_1 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 295.0
HFD1_k127_3720095_2 Nucleoside-diphosphate-sugar epimerase K07276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003147 284.0
HFD1_k127_3720095_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000008121 235.0
HFD1_k127_3720095_4 Mitochondrial fission ELM1 K07276 - - 0.0000000000000000001671 92.0
HFD1_k127_3730202_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 436.0
HFD1_k127_3730202_1 Cytochrome c-type biogenesis protein K02198 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - 0.00000000000000000000000000000000000000000000000000002224 194.0
HFD1_k127_3730202_2 Thiol disulfide interchange protein K02199 GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:0140096 - 0.00000000000000000000000000000000000000000000000000006872 195.0
HFD1_k127_3730202_3 subunit of a heme lyase K02200 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567 - 0.000000000000000000000000000000000001095 145.0
HFD1_k127_3730202_4 helix_turn_helix gluconate operon transcriptional repressor - - - 0.0000000000000000000000000000005575 131.0
HFD1_k127_3730202_5 COG4235 Cytochrome c biogenesis factor K02200 - - 0.000000000000000000000000000006157 138.0
HFD1_k127_3730202_6 Cytochrome C biogenesis K02200 - - 0.000000000005611 79.0
HFD1_k127_3739913_0 Belongs to the UPF0061 (SELO) family - - - 3.084e-232 730.0
HFD1_k127_3739913_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001897 254.0
HFD1_k127_3739913_2 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000002441 223.0
HFD1_k127_374446_0 Glucose dehydrogenase - - - 2.946e-224 713.0
HFD1_k127_374446_1 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.0000009448 51.0
HFD1_k127_374446_2 Tetratricopeptide repeat - - - 0.000002843 59.0
HFD1_k127_3748696_0 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006212 263.0
HFD1_k127_3748696_1 NADH-ubiquinone oxidoreductase chain 49kDa - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002014 244.0
HFD1_k127_3748696_2 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000005513 217.0
HFD1_k127_375566_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 616.0
HFD1_k127_375566_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 511.0
HFD1_k127_375566_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000001843 244.0
HFD1_k127_375566_3 Preprotein translocase K03210 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000003513 138.0
HFD1_k127_3758567_0 Prolyl oligopeptidase family - - - 4.488e-202 636.0
HFD1_k127_3758567_1 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 322.0
HFD1_k127_3758567_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003159 284.0
HFD1_k127_3758567_3 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001469 285.0
HFD1_k127_3758567_4 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005773 253.0
HFD1_k127_3758567_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000002366 165.0
HFD1_k127_3758567_6 HAD-superfamily hydrolase, subfamily IIB - - - 0.000000000000000000000000000001045 131.0
HFD1_k127_3771469_0 COG0657 Esterase lipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008659 324.0
HFD1_k127_3771469_1 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003356 262.0
HFD1_k127_3771469_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000001112 149.0
HFD1_k127_3782132_0 LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 378.0
HFD1_k127_3782132_1 Pyridoxamine 5'-phosphate K07006 - - 0.0000000002147 65.0
HFD1_k127_3782316_0 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 318.0
HFD1_k127_3782316_1 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006916 281.0
HFD1_k127_3782316_2 COG1512 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.000000000000000000000000000000000000000000000000000000000000003183 226.0
HFD1_k127_3782316_3 Membrane K08988 - - 0.000000000000000000000000000000000000000000000000000000003686 205.0
HFD1_k127_3782316_4 PFAM TM2 domain - - - 0.000000000000000000000000001918 127.0
HFD1_k127_3782316_5 - - - - 0.000002652 59.0
HFD1_k127_3797276_0 PFAM helix-turn-helix domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 336.0
HFD1_k127_3797276_1 Serine aminopeptidase, S33 K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009999 327.0
HFD1_k127_3797276_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000001858 241.0
HFD1_k127_3797276_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000002236 171.0
HFD1_k127_3798068_0 Penicillin amidase - - - 1.146e-272 859.0
HFD1_k127_3798068_1 COG2148 Sugar transferases involved in lipopolysaccharide synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 422.0
HFD1_k127_3798068_2 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006826 347.0
HFD1_k127_3798068_3 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 321.0
HFD1_k127_3798068_4 Peptidoglycan-binding domain 1 protein - - - 0.000000000003662 76.0
HFD1_k127_3798068_5 Protein of unknown function (DUF1631) - - - 0.0000002473 61.0
HFD1_k127_3798068_6 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02462 - - 0.0004005 46.0
HFD1_k127_3820693_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145,K05829 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 298.0
HFD1_k127_3820693_1 Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006315 255.0
HFD1_k127_3820693_2 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000005417 222.0
HFD1_k127_3820693_3 - - - - 0.00000000000000000000000000000000000000000000000000000006493 202.0
HFD1_k127_3820693_4 COG1132 ABC-type multidrug transport system, ATPase and permease components K06147,K11085 - - 0.00000000000000000000000000000000000000000000001841 173.0
HFD1_k127_3820693_5 - - - - 0.0000000000000000000000000000000000001976 154.0
HFD1_k127_3842368_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 6.252e-215 680.0
HFD1_k127_3843346_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K13525 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002024 301.0
HFD1_k127_3843346_1 mitochondrion organization K01338,K13525 - 3.4.21.53 0.0000000000000000000000000000007058 143.0
HFD1_k127_3854721_0 Biotin carboxylase C-terminal domain - - - 3.848e-227 720.0
HFD1_k127_3854721_1 Nitroreductase family K04719 - 1.13.11.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000001183 263.0
HFD1_k127_3856256_0 Molydopterin dinucleotide binding domain K07306,K07309,K07310,K08351 - 1.8.5.3,1.97.1.9 3.129e-311 971.0
HFD1_k127_3856256_1 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 304.0
HFD1_k127_3856256_2 COG2513 PEP phosphonomutase and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 296.0
HFD1_k127_3856256_3 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000002988 261.0
HFD1_k127_3856256_4 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000008225 239.0
HFD1_k127_3872623_0 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003824,GO:0004411,GO:0005488,GO:0005506,GO:0005575,GO:0006082,GO:0006355,GO:0006520,GO:0006558,GO:0006559,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0019219,GO:0019222,GO:0019439,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0045892,GO:0045934,GO:0046395,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051213,GO:0051252,GO:0051253,GO:0055114,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902221,GO:1902222,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 1.13.11.5 4.122e-202 636.0
HFD1_k127_3872623_1 4-hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 506.0
HFD1_k127_3872623_2 Bacterial virulence protein (VirJ) - - - 0.000000000000000000000000000000000000000000000000001161 191.0
HFD1_k127_3883673_0 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000000000000000000000347 191.0
HFD1_k127_3883673_1 Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000001275 180.0
HFD1_k127_3883673_2 G-rich domain on putative tyrosine kinase - - - 0.00000000000000000000000000000000000000000001126 177.0
HFD1_k127_3883673_3 - - - - 0.00000000000000000000000000000000002075 144.0
HFD1_k127_3883673_4 Chain length determinant protein tyrosine kinase EpsG K08252 - 2.7.10.1 0.00000000000000000000000000000003419 141.0
HFD1_k127_3883673_5 Transcriptional regulatory protein, C terminal - - - 0.0000000000000006187 89.0
HFD1_k127_3913527_0 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 501.0
HFD1_k127_3913527_1 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000008086 123.0
HFD1_k127_3913743_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 597.0
HFD1_k127_3913743_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 447.0
HFD1_k127_3913743_2 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005817 259.0
HFD1_k127_3913743_3 Cytochrome b561 K12262 - - 0.000000000000000000000000000000000000006686 152.0
HFD1_k127_3913743_5 Belongs to the UPF0312 family - - - 0.000000000000000000000000004084 124.0
HFD1_k127_3913743_6 isoform X1 - - - 0.0000000000000000000000002683 114.0
HFD1_k127_3913743_7 Invasion gene expression up-regulator, SirB - - - 0.000000000000000000000000701 109.0
HFD1_k127_3913743_8 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000001673 81.0
HFD1_k127_3913743_9 Aminotransferase class-III K01845 - 5.4.3.8 0.0002559 46.0
HFD1_k127_3914738_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 381.0
HFD1_k127_3914738_1 KR domain K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000004113 272.0
HFD1_k127_3914738_2 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002255 234.0
HFD1_k127_3914738_3 glutathione transferase activity - - - 0.0000000000000000000000000000000000006853 145.0
HFD1_k127_3920740_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 484.0
HFD1_k127_3920740_1 COG0657 Esterase lipase K14731 - 3.1.1.83 0.0000000000000006217 85.0
HFD1_k127_3931172_0 Aldo/keto reductase family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0017144,GO:0034641,GO:0042723,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:1901360,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 550.0
HFD1_k127_3931172_1 metal-dependent hydrolase of the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 347.0
HFD1_k127_3931172_2 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000027 230.0
HFD1_k127_3938907_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 337.0
HFD1_k127_3938907_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006947 280.0
HFD1_k127_3938907_2 Anti sigma-E protein RseA, N-terminal domain K03597 - - 0.000000000000004679 83.0
HFD1_k127_3953728_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.083e-228 716.0
HFD1_k127_3953728_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 505.0
HFD1_k127_3953728_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0000287,GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1990928 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 475.0
HFD1_k127_3953728_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 314.0
HFD1_k127_3953728_4 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 291.0
HFD1_k127_3953728_5 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.0000000000000002873 83.0
HFD1_k127_3953728_6 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00001719 46.0
HFD1_k127_3959923_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 1.132e-234 744.0
HFD1_k127_3959923_1 ArsR family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000001193 194.0
HFD1_k127_3978448_0 Dehydrogenase K15371 - 1.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 449.0
HFD1_k127_3978448_1 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 436.0
HFD1_k127_3978448_2 phenylacetic acid degradation operon negative regulatory protein K02616 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006082,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006805,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010124,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010817,GO:0016054,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019439,GO:0019748,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0032774,GO:0032787,GO:0034641,GO:0034645,GO:0034654,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043170,GO:0043254,GO:0043436,GO:0043565,GO:0044087,GO:0044212,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044282,GO:0045892,GO:0045934,GO:0046395,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0098754,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901575,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000007165 256.0
HFD1_k127_3978448_3 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 K02613 GO:0000166,GO:0003674,GO:0005488,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0036094,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0097159,GO:0098754,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - 0.000000000000000000000000000000000000000000001384 167.0
HFD1_k127_3978448_4 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.000000000000000000000000000000000001748 144.0
HFD1_k127_3978448_5 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0015976,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.266 0.0000000000000000004803 89.0
HFD1_k127_3982598_0 O-acetylhomoserine K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007168 287.0
HFD1_k127_3982598_1 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003424 266.0
HFD1_k127_3982598_2 CoA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000007751 217.0
HFD1_k127_3984668_0 ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component K02004 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 5.877e-225 724.0
HFD1_k127_3984668_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000215 115.0
HFD1_k127_3984668_2 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000001094 68.0
HFD1_k127_3987422_0 Malate synthase K01638 - 2.3.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 361.0
HFD1_k127_3987422_1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000000000000037 187.0
HFD1_k127_3987422_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000002864 83.0
HFD1_k127_4005970_0 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002685 275.0
HFD1_k127_4005970_1 amidohydrolase K12941 - - 0.00000000000000000000000000000000000000000000000000000000000194 215.0
HFD1_k127_4006567_0 DEAD/H associated K03724 - - 5.472e-320 1013.0
HFD1_k127_4006567_1 Protein of unknown function (DUF1282) - - - 0.00000000000000000000000000000000000000000000000000001466 198.0
HFD1_k127_4019765_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 554.0
HFD1_k127_4019765_1 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 508.0
HFD1_k127_4019765_10 - - - - 0.00000000000000000000000002852 124.0
HFD1_k127_4019765_11 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000001014 83.0
HFD1_k127_4019765_12 NfeD-like C-terminal, partner-binding - - - 0.000000000000005467 80.0
HFD1_k127_4019765_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 448.0
HFD1_k127_4019765_3 Peptidase M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 419.0
HFD1_k127_4019765_4 SMART band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007047 381.0
HFD1_k127_4019765_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019538,GO:0030163,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0052689,GO:0071704,GO:0140098,GO:0140101,GO:1901564,GO:1901565,GO:1901575 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000004623 213.0
HFD1_k127_4019765_6 Belongs to the UPF0502 family K09915 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000351 207.0
HFD1_k127_4019765_7 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000002802 204.0
HFD1_k127_4019765_8 Thioesterase superfamily - - - 0.0000000000000000000000000000001404 128.0
HFD1_k127_4019765_9 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000258 131.0
HFD1_k127_4029422_0 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 426.0
HFD1_k127_4029422_1 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 383.0
HFD1_k127_4029422_2 Belongs to the RbsD FucU family K02431 GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0005996,GO:0006004,GO:0008150,GO:0008152,GO:0016853,GO:0016854,GO:0016857,GO:0019318,GO:0030246,GO:0036094,GO:0042806,GO:0044238,GO:0044281,GO:0048029,GO:0071704 5.1.3.29 0.00000000000000000000000000000000004351 146.0
HFD1_k127_4034723_0 Flavin-binding monooxygenase-like - - - 9.944e-258 814.0
HFD1_k127_4034723_1 Hsp20/alpha crystallin family - - - 0.000000000000000000000000000000000000003857 150.0
HFD1_k127_4034723_2 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000008115 94.0
HFD1_k127_4037127_0 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 333.0
HFD1_k127_4037127_1 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000001875 219.0
HFD1_k127_4037127_2 cellular response to dsDNA K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000001383 179.0
HFD1_k127_4037127_3 lactoylglutathione lyase activity - - - 0.00000000000000000000000000004541 121.0
HFD1_k127_4037127_4 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000006677 68.0
HFD1_k127_4037127_5 Bacterial regulatory proteins, tetR family K16137 - - 0.0000004155 54.0
HFD1_k127_4060389_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 453.0
HFD1_k127_4060389_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000002773 208.0
HFD1_k127_4060389_2 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000216 141.0
HFD1_k127_4062001_0 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 409.0
HFD1_k127_4062001_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000918 167.0
HFD1_k127_4062001_2 - - - - 0.00000000000000000000000000000002038 138.0
HFD1_k127_4062001_3 TIR domain - - - 0.00000000000000001561 98.0
HFD1_k127_4077749_0 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 491.0
HFD1_k127_4077749_1 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007326 259.0
HFD1_k127_4077749_2 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005768 250.0
HFD1_k127_4077749_3 Rieske 2Fe-2S - - - 0.000000009896 60.0
HFD1_k127_4077757_0 Biotin carboxylase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 384.0
HFD1_k127_4077757_1 NlpC/P60 family - - - 0.00000000000000000000000000004622 122.0
HFD1_k127_4077757_2 dioxygenase activity - - - 0.0000000000000000000000307 112.0
HFD1_k127_4077757_3 - - - - 0.0000000000000000000002983 102.0
HFD1_k127_4077757_4 Water Stress and Hypersensitive response - - - 0.00000009437 57.0
HFD1_k127_4080540_0 NAD(P)-binding Rossmann-like domain K00316 - 1.5.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 560.0
HFD1_k127_4080540_1 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 460.0
HFD1_k127_4080540_2 Bacterial extracellular solute-binding protein K11073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 333.0
HFD1_k127_4127670_0 Repeat of Unknown Function (DUF347) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 383.0
HFD1_k127_4127670_1 KR domain - - - 0.000000000000000000000000000000000000000000001004 174.0
HFD1_k127_4127670_2 Domain of unknown function (DUF4870) - - - 0.000000000000001902 83.0
HFD1_k127_4127670_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079 - - 0.0000000000001063 74.0
HFD1_k127_416235_0 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 366.0
HFD1_k127_416235_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000000002307 225.0
HFD1_k127_416235_2 Translation-initiation factor 2 K02519 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000009483 142.0
HFD1_k127_416235_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000009045 132.0
HFD1_k127_416235_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000001708 121.0
HFD1_k127_4169435_0 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 604.0
HFD1_k127_4169435_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 421.0
HFD1_k127_4169435_2 FAD linked oxidase K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 374.0
HFD1_k127_4169435_3 FAD binding domain K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 338.0
HFD1_k127_4169435_4 redox protein, regulator of disulfide bond formation - - - 0.0000000000000000000000000000000000000001309 154.0
HFD1_k127_4169435_5 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000002278 57.0
HFD1_k127_4184377_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.47e-274 866.0
HFD1_k127_4184377_1 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 561.0
HFD1_k127_4184377_2 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 419.0
HFD1_k127_4184377_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 339.0
HFD1_k127_4184377_4 dUTPase - - - 0.000000000000000000000000000000000000000000000000007771 185.0
HFD1_k127_4184377_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000009992 158.0
HFD1_k127_4184377_6 dienelactone hydrolase - - - 0.000000000000000000000006492 111.0
HFD1_k127_4187219_0 Alanine-glyoxylate amino-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 498.0
HFD1_k127_4187219_1 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 476.0
HFD1_k127_4187219_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000007438 57.0
HFD1_k127_4188491_0 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 560.0
HFD1_k127_4188491_1 receiver - - - 0.00000000000000000000000000000000000001565 158.0
HFD1_k127_4188491_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000006845 88.0
HFD1_k127_4191355_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 303.0
HFD1_k127_4191355_1 Belongs to the BI1 family K19416 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016021,GO:0019222,GO:0030162,GO:0031224,GO:0044425,GO:0044464,GO:0050789,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071944,GO:0080090 - 0.000000000000000000000000000000000000000000000000000000000000000000000001292 251.0
HFD1_k127_4191355_2 Von Willebrand factor type A K02448 - - 0.000000000000000000000000000000000000000000000002261 178.0
HFD1_k127_4191355_3 Acetyl-coenzyme A transporter 1 - - - 0.00000000000000000001573 99.0
HFD1_k127_4191355_4 DnaK suppressor protein - - - 0.00000000000000000005268 93.0
HFD1_k127_419147_0 Belongs to the GST superfamily K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 327.0
HFD1_k127_419147_1 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001843 263.0
HFD1_k127_419147_2 Sterol carrier protein domain - - - 0.00000000000000000000000000000000000000000000123 181.0
HFD1_k127_419147_3 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000001263 169.0
HFD1_k127_419797_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113,GO:2000765,GO:2000766 - 1.862e-280 871.0
HFD1_k127_419797_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006520,GO:0006553,GO:0006563,GO:0006564,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009085,GO:0009089,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0019842,GO:0030170,GO:0033359,GO:0034641,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046394,GO:0046451,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901615,GO:1901617 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 477.0
HFD1_k127_419797_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 437.0
HFD1_k127_419797_3 chorismate mutase K04518,K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 437.0
HFD1_k127_419797_4 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 329.0
HFD1_k127_419797_5 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000449 244.0
HFD1_k127_419797_6 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008653,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1903509 - 0.000000000000000000000000000000000000000000000000000000000000002821 229.0
HFD1_k127_419797_7 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000009912 205.0
HFD1_k127_419797_8 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2001141 - 0.000000000000000000000000000000000000000000002373 166.0
HFD1_k127_4199965_0 Efflux pump membrane transporter K18138 - - 0.0 1026.0
HFD1_k127_4199965_1 Amidase, hydantoinase carbamoylase family K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 524.0
HFD1_k127_4199965_2 PFAM Amidohydrolase 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 417.0
HFD1_k127_4199965_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008312 397.0
HFD1_k127_4199965_4 Major facilitator Superfamily - - - 0.000000000000000000004107 94.0
HFD1_k127_4207183_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 345.0
HFD1_k127_4207183_1 serine acetyltransferase K00640 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009314,GO:0009333,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 347.0
HFD1_k127_4207183_2 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 321.0
HFD1_k127_4207183_3 Protein of unknown function (DUF2797) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008931 274.0
HFD1_k127_4207183_4 aminopeptidase N K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000002627 222.0
HFD1_k127_4207183_5 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000000000000000000000000000000005008 138.0
HFD1_k127_4207183_6 membrane protein (homolog of Drosophila rhomboid) K02441 - - 0.000000000000000000000000000000006116 139.0
HFD1_k127_4208277_0 MlaD protein K06192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 585.0
HFD1_k127_4208277_1 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 GO:0003674,GO:0005215,GO:0005372,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006833,GO:0006884,GO:0006950,GO:0006970,GO:0008150,GO:0008361,GO:0009628,GO:0009987,GO:0009992,GO:0015250,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0042044,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0050896,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 390.0
HFD1_k127_4208277_2 integral membrane protein, PqiA family K03808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000157 271.0
HFD1_k127_4208277_3 PFAM Paraquat-inducible protein A K03808 - - 0.00000000000000000000000000000000000000000000006062 177.0
HFD1_k127_4208277_4 ABC-type transport auxiliary lipoprotein component K09857 - - 0.000000000000000000000000000000004306 137.0
HFD1_k127_4208277_5 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion K02564 - 3.5.99.6 0.0007555 45.0
HFD1_k127_4226563_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 339.0
HFD1_k127_4226563_1 COG2202 FOG PAS PAC domain K21025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009839 292.0
HFD1_k127_4226563_2 lysine 2,3-aminomutase K19810 - - 0.0000000000000000000000000000000000000006625 150.0
HFD1_k127_4226918_0 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 550.0
HFD1_k127_4226918_1 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000003536 193.0
HFD1_k127_4226918_2 Taurine catabolism dioxygenase TauD, TfdA - - - 0.00004129 50.0
HFD1_k127_4227508_0 Alkyl sulfatase and related hydrolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 556.0
HFD1_k127_4227508_1 Zn-dependent alcohol dehydrogenases K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006489 458.0
HFD1_k127_4227508_2 COG0534 Na -driven multidrug efflux pump - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 392.0
HFD1_k127_4227508_3 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000005652 188.0
HFD1_k127_4227508_4 Carboxylesterase family - - - 0.0000000000000000000000000000000000000000000000000008736 193.0
HFD1_k127_4227508_5 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000003495 153.0
HFD1_k127_4227508_6 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000005084 134.0
HFD1_k127_4249674_0 cytochrome P450 K05525 - 1.14.13.151 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009671 430.0
HFD1_k127_4249674_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K13525 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 409.0
HFD1_k127_4249674_2 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000005193 100.0
HFD1_k127_4249674_3 Glycosyl transferase 4-like domain K08256,K12995 - 2.4.1.345,2.4.1.348 0.000000003912 64.0
HFD1_k127_4250431_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 3.494e-246 770.0
HFD1_k127_4250431_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000007966 152.0
HFD1_k127_4251873_0 Magnesium chelatase, subunit ChlI K03974 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 452.0
HFD1_k127_4251873_1 Belongs to the bacterial solute-binding protein 3 family K01713 - 4.2.1.51,4.2.1.91 0.000000000000000000000000000000000000000000000000000000000002918 218.0
HFD1_k127_4251873_2 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription K03969 GO:0003674,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0008289,GO:0009266,GO:0009271,GO:0009408,GO:0009605,GO:0009607,GO:0009615,GO:0009628,GO:0009889,GO:0009898,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019897,GO:0019898,GO:0031234,GO:0031323,GO:0031326,GO:0042802,GO:0043167,GO:0043168,GO:0043207,GO:0043433,GO:0044092,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0050896,GO:0051090,GO:0051171,GO:0051252,GO:0051704,GO:0051707,GO:0060187,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0098552,GO:0098562,GO:0098586,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000008941 184.0
HFD1_k127_4251873_3 - K03418 - 3.5.1.56 0.0000002636 57.0
HFD1_k127_4252251_0 Enoyl-CoA hydratase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000007781 268.0
HFD1_k127_4252251_1 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000006669 203.0
HFD1_k127_4252251_2 COG1398 Fatty-acid desaturase K00507 - 1.14.19.1 0.000000000000005108 79.0
HFD1_k127_4258024_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 420.0
HFD1_k127_4258024_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003271 259.0
HFD1_k127_4258024_2 Outer membrane usher protein K07347 - - 0.000000000000000000000000000000000000000000000000000005361 200.0
HFD1_k127_4258024_3 Pili and flagellar-assembly chaperone, PapD N-terminal domain K07346 - - 0.000000000000000000000000000000000000000000002351 173.0
HFD1_k127_4258024_4 Spore Coat Protein U domain - - - 0.000000000000000001897 92.0
HFD1_k127_4258024_5 Belongs to the UPF0270 family K09898 - - 0.0000000008919 62.0
HFD1_k127_4265062_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 353.0
HFD1_k127_4265062_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000004649 223.0
HFD1_k127_4265062_2 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000001765 109.0
HFD1_k127_4269930_0 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 312.0
HFD1_k127_4269930_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006485 323.0
HFD1_k127_4269930_2 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000008697 234.0
HFD1_k127_4269930_3 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000004382 185.0
HFD1_k127_4269930_4 Sigma-70, region 4 K03088 - - 0.0001846 44.0
HFD1_k127_4272179_0 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 300.0
HFD1_k127_4272179_1 Acyl-CoA dehydrogenase, middle domain K06446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 282.0
HFD1_k127_4272179_2 HDOD domain - - - 0.0000000000000000000000000000000000000002422 170.0
HFD1_k127_4281033_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 398.0
HFD1_k127_4281033_1 Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.000000000000000000000000000000000000001261 150.0
HFD1_k127_4281033_2 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000006083 125.0
HFD1_k127_4281033_3 amino acid K16263 - - 0.0000000006271 65.0
HFD1_k127_4286012_0 Sugar (and other) transporter K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 602.0
HFD1_k127_4286012_1 HlyD family secretion protein K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 329.0
HFD1_k127_4288311_0 acetyl-CoA hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 302.0
HFD1_k127_4288311_1 peptidase S9 K01354 - 3.4.21.83 0.00000000000000000000000000000000000000000000000000000000000000000002729 233.0
HFD1_k127_4292750_0 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006043 513.0
HFD1_k127_4292750_1 MaoC like domain K18290 - 4.2.1.56 0.0000000000000000000000000000000000000000000000000000002467 196.0
HFD1_k127_4292750_2 dehydratase - - - 0.00000000000000000000000000000000000000000000000000004562 198.0
HFD1_k127_4292750_3 Belongs to the HpcH HpaI aldolase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.000000000000003012 85.0
HFD1_k127_4303442_0 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009259 468.0
HFD1_k127_4303442_1 Enoyl-CoA hydratase carnithine racemase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009878 361.0
HFD1_k127_4303442_2 COG0457 FOG TPR repeat - - - 0.0000000000000001416 85.0
HFD1_k127_4307188_0 Carboxyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009054 466.0
HFD1_k127_4307188_1 - - - - 0.000000008646 68.0
HFD1_k127_4313390_0 ABC transporter transmembrane region K06147 - - 1.874e-195 629.0
HFD1_k127_4313390_1 Acetyltransferase (GNAT) domain - - - 0.000000000000003097 85.0
HFD1_k127_4331345_0 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001244 263.0
HFD1_k127_4331345_1 dioxygenase activity - GO:0008150,GO:0008152,GO:0009058,GO:0019748,GO:0044550,GO:0071704,GO:1900558,GO:1900560,GO:1900561,GO:1900563,GO:1901576 - 0.000000000000000000000000000000000000000000000000000006712 215.0
HFD1_k127_4331345_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000004067 64.0
HFD1_k127_4331345_3 acyl-CoA dehydrogenase K22027 - 1.14.13.235 0.00000000004981 67.0
HFD1_k127_4352374_0 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 1.141e-204 641.0
HFD1_k127_4352374_1 AMP-binding enzyme C-terminal domain K00666 - - 1.635e-200 640.0
HFD1_k127_4352374_10 Domain of unknown function (DUF4399) - - - 0.000000000000000000000000000000000000000000001923 175.0
HFD1_k127_4352374_11 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000001651 144.0
HFD1_k127_4352374_12 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000001593 109.0
HFD1_k127_4352374_13 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0001808 48.0
HFD1_k127_4352374_2 metal-dependent hydrolase of the TIM-barrel fold K07046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 494.0
HFD1_k127_4352374_3 Sulfate permease family K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 422.0
HFD1_k127_4352374_4 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005723 330.0
HFD1_k127_4352374_5 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000321 287.0
HFD1_k127_4352374_6 Serine aminopeptidase, S33 K22369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001009 252.0
HFD1_k127_4352374_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004598 256.0
HFD1_k127_4352374_8 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000001855 205.0
HFD1_k127_4352374_9 protein transport - - - 0.0000000000000000000000000000000000000000000000002318 181.0
HFD1_k127_4361154_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 1.466e-258 807.0
HFD1_k127_4361154_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 451.0
HFD1_k127_4361154_2 N-terminal domain of oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 414.0
HFD1_k127_4361154_3 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 380.0
HFD1_k127_4361154_4 Di-haem cytochrome c peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009259 381.0
HFD1_k127_4361154_5 Nitronate monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 370.0
HFD1_k127_4361154_6 dioxygenase activity K18562 - - 0.0000000000000000000000000000000000000000000000000000001991 203.0
HFD1_k127_4361154_7 protein conserved in bacteria K09986 - - 0.00000000000000000000000000000000000000000000000000002643 192.0
HFD1_k127_4361154_8 Electron transfer flavoprotein K03522 - - 0.0000000000000000000000000000000000001629 143.0
HFD1_k127_4366352_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 477.0
HFD1_k127_4366352_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 352.0
HFD1_k127_4366352_2 Belongs to the 'phage' integrase family. XerC subfamily K03733 GO:0000150,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0042150,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 298.0
HFD1_k127_4366352_3 hydrolase K20862 - 3.1.3.102,3.1.3.104 0.00000000000000000000000000000000000000000000000001033 189.0
HFD1_k127_4366352_4 Protein of unknown function, DUF484 K09921 - - 0.00000000000000000000000000000000000000000449 168.0
HFD1_k127_4366756_0 TIM-barrel fold metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000005212 183.0
HFD1_k127_4366756_1 transcriptional regulator - - - 0.00000000000000000000000000000001264 136.0
HFD1_k127_4371149_0 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009414 463.0
HFD1_k127_4371149_1 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 308.0
HFD1_k127_4371149_2 Cupin domain - - - 0.00000000000000000000000000000000000000000000000009332 186.0
HFD1_k127_4371149_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000002102 171.0
HFD1_k127_4371149_4 ethanolamine kinase activity K07251 - 2.7.1.89 0.000000000006178 78.0
HFD1_k127_4371179_0 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 456.0
HFD1_k127_4371179_1 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000004602 267.0
HFD1_k127_4371179_2 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004278 256.0
HFD1_k127_4371179_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000726 256.0
HFD1_k127_4371179_4 Thermostable hemolysin - - - 0.000000000000002958 85.0
HFD1_k127_4371179_5 SnoaL-like domain - - - 0.00000000000213 69.0
HFD1_k127_4371179_6 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000001116 60.0
HFD1_k127_4395119_0 COG0131 Imidazoleglycerol-phosphate dehydratase K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 316.0
HFD1_k127_4395119_1 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814,K01817 - 5.3.1.16,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006306 289.0
HFD1_k127_4395119_2 - - - - 0.00000000000000001283 87.0
HFD1_k127_4395119_3 involved in outer membrane biogenesis K07289 - - 0.000000000008884 77.0
HFD1_k127_4417270_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 6.041e-213 672.0
HFD1_k127_4417270_1 RimK-like ATPgrasp N-terminal domain - - - 4.142e-196 622.0
HFD1_k127_4417270_2 Glutamate-cysteine ligase family 2(GCS2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 461.0
HFD1_k127_4417270_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002822 269.0
HFD1_k127_4417270_4 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000001 139.0
HFD1_k127_4418097_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 534.0
HFD1_k127_4418097_1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000001938 258.0
HFD1_k127_4418097_2 Site-specific recombinase, DNA invertase Pin - - - 0.0001929 48.0
HFD1_k127_4422100_0 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 591.0
HFD1_k127_4422100_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 376.0
HFD1_k127_4422100_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030554,GO:0032991,GO:0036094,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071840,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000002507 173.0
HFD1_k127_4422100_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000003253 59.0
HFD1_k127_4456776_0 FAD binding domain - - - 8.987e-224 711.0
HFD1_k127_4456776_1 Cro/C1-type HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000571 238.0
HFD1_k127_4456776_2 N-acetyltransferase K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000001467 209.0
HFD1_k127_4456776_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000002666 198.0
HFD1_k127_4456776_4 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000000000000001315 173.0
HFD1_k127_4456776_5 Alpha beta hydrolase - - - 0.00000000000000000000000000000000008756 144.0
HFD1_k127_4456776_6 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000001248 97.0
HFD1_k127_4456776_7 Domain of unknown function (DUF1772) - - - 0.0000000000000000000002773 106.0
HFD1_k127_4456776_8 Ketosteroid isomerase-related protein - - - 0.0000000000000000005084 91.0
HFD1_k127_4456776_9 Cytochrome P450 - - - 0.00000001203 56.0
HFD1_k127_4459454_0 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 343.0
HFD1_k127_4459454_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002448 284.0
HFD1_k127_4464639_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 525.0
HFD1_k127_4464639_1 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000006149 206.0
HFD1_k127_4464639_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000002664 124.0
HFD1_k127_4464639_3 Tetratricopeptide repeat K12284 - - 0.000000009193 62.0
HFD1_k127_4487309_0 type II secretion system protein E K02454 - - 8.192e-209 661.0
HFD1_k127_4487309_1 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 508.0
HFD1_k127_4487309_10 general secretion pathway protein K02458 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000000000000000002729 90.0
HFD1_k127_4487309_11 Fe2 -dicitrate sensor, membrane component K07165 - - 0.000001554 52.0
HFD1_k127_4487309_12 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02462 - - 0.000008844 51.0
HFD1_k127_4487309_2 general secretion pathway protein K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 419.0
HFD1_k127_4487309_3 Electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 338.0
HFD1_k127_4487309_4 General Secretion Pathway protein K02456 - - 0.000000000000000000000000000000000000000000000000004005 184.0
HFD1_k127_4487309_5 Type II secretion system (T2SS), protein K K02460 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000001873 183.0
HFD1_k127_4487309_6 General secretion pathway protein J K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.00000000000000000000000000000000000001047 153.0
HFD1_k127_4487309_7 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000001638 131.0
HFD1_k127_4487309_8 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.0000000000000000000000000000003234 138.0
HFD1_k127_4487309_9 general secretion pathway protein H K02457 - - 0.0000000000000000000007959 101.0
HFD1_k127_4507282_0 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 511.0
HFD1_k127_4507282_1 TonB C terminal K03832 - - 0.000000000000000000000000000000000000000247 162.0
HFD1_k127_4507282_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043933,GO:0044085,GO:0044464,GO:0051259,GO:0051260,GO:0051301,GO:0065003,GO:0071840 - 0.000000000000000000000000000000000000002207 161.0
HFD1_k127_4507282_3 Biopolymer transport protein K03560 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032153,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000001001 148.0
HFD1_k127_4507282_4 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000007377 145.0
HFD1_k127_4513546_0 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009524 334.0
HFD1_k127_4513546_1 Predicted membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 286.0
HFD1_k127_4513546_2 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005731 248.0
HFD1_k127_4513546_3 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K03830 - - 0.0000000000000000000000000000000000000000000000000001182 190.0
HFD1_k127_4513546_4 Glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000000000000000006379 139.0
HFD1_k127_4513546_5 - - - - 0.00000000000000000000000000000001708 139.0
HFD1_k127_4513546_6 lactoylglutathione lyase activity K00941,K01724,K01759,K07032,K08234 - 2.7.1.49,2.7.4.7,4.2.1.96,4.4.1.5 0.00003424 53.0
HFD1_k127_4518902_0 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 530.0
HFD1_k127_4518902_1 Ion transport protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 321.0
HFD1_k127_4518902_2 acetyltransferase - - - 0.00000000000000000000000000000000000000000001118 188.0
HFD1_k127_4518902_3 CDP-archaeol synthase K19664 - 2.7.7.67 0.0000000000000000000000000000000000000997 147.0
HFD1_k127_4518902_4 Cysteine-rich CPXCG - - - 0.00000000000000001277 84.0
HFD1_k127_4518902_5 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.000000000000001841 87.0
HFD1_k127_4521488_0 taurine catabolism dioxygenase K22303 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016705,GO:0016706,GO:0051213,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008539 435.0
HFD1_k127_4521488_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000001078 213.0
HFD1_k127_4521488_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000002303 183.0
HFD1_k127_4526819_0 Adventurous gliding motility protein R - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001426 257.0
HFD1_k127_4526819_1 NmrA-like family - - - 0.0000000000000000000000000000000000000000000001319 172.0
HFD1_k127_4526819_2 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.00000008557 61.0
HFD1_k127_453072_0 COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT K02669 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 605.0
HFD1_k127_453072_1 twitching motility protein K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 574.0
HFD1_k127_453072_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000006087 233.0
HFD1_k127_453072_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000001241 211.0
HFD1_k127_453072_4 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00005936 47.0
HFD1_k127_4531892_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 529.0
HFD1_k127_4531892_1 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005573 361.0
HFD1_k127_4531892_2 Zeta toxin - - - 0.00000000000000000000000000000000000000000000000000000003947 202.0
HFD1_k127_4531892_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000004512 167.0
HFD1_k127_4531892_4 Cupin domain - - - 0.00000000000000000000000000000000000000536 147.0
HFD1_k127_4531892_5 AraC-like ligand binding domain - - - 0.000000000000000000000769 100.0
HFD1_k127_4531892_6 Water Stress and Hypersensitive response - - - 0.000004603 51.0
HFD1_k127_4541497_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 9.527e-209 662.0
HFD1_k127_4541497_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 6.611e-196 621.0
HFD1_k127_4541497_2 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 362.0
HFD1_k127_4544255_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 5.224e-239 751.0
HFD1_k127_4544255_1 UPF0761 membrane protein K07058 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001156 284.0
HFD1_k127_4544255_2 Belongs to the WrbA family K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000004887 260.0
HFD1_k127_4544255_3 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000000000000000000000000000000000000000000001492 183.0
HFD1_k127_4544255_4 arsenate reductase K00537 - 1.20.4.1 0.000000000000000000000000000000000000000002854 158.0
HFD1_k127_4544255_5 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000003337 141.0
HFD1_k127_4544255_6 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01908 - 6.2.1.17 0.0000000000000000000000000003354 115.0
HFD1_k127_4544255_7 Predicted membrane protein (DUF2069) - - - 0.0000001267 58.0
HFD1_k127_4553810_0 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000087 220.0
HFD1_k127_4553810_1 Autotransporter beta-domain - - - 0.000000000000000000000000000003394 129.0
HFD1_k127_4564454_0 phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 452.0
HFD1_k127_4564454_1 Putative diguanylate phosphodiesterase K21025 - - 0.0000000000000000000000000000000000000000000000000000001806 198.0
HFD1_k127_4564454_2 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.000000000000000000000000000000001763 131.0
HFD1_k127_4564454_3 Bacterial virulence factor haemolysin K07186 - - 0.0005042 52.0
HFD1_k127_4577142_0 catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 284.0
HFD1_k127_4577142_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001233 242.0
HFD1_k127_4577142_2 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000002293 201.0
HFD1_k127_4587156_0 Belongs to the peptidase S1C family K04691,K04771,K04772 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000001483 264.0
HFD1_k127_4587156_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.00000000000000000000000000007671 122.0
HFD1_k127_4588210_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 424.0
HFD1_k127_4588210_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007846 346.0
HFD1_k127_4588210_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000006584 254.0
HFD1_k127_4588210_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000003422 232.0
HFD1_k127_4588210_4 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000003198 217.0
HFD1_k127_4588210_5 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000001559 154.0
HFD1_k127_4588210_6 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000001382 152.0
HFD1_k127_4593781_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 406.0
HFD1_k127_4593781_1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 291.0
HFD1_k127_4593781_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 0.0000000000000000000000000000000004223 131.0
HFD1_k127_4609854_0 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 572.0
HFD1_k127_4645225_0 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 508.0
HFD1_k127_4645225_1 PFAM aldo keto reductase K05882 - 1.1.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 389.0
HFD1_k127_4645225_2 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000003136 214.0
HFD1_k127_4654817_0 COG2124 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000003306 209.0
HFD1_k127_4654817_1 cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000004574 184.0
HFD1_k127_4668776_0 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009084 374.0
HFD1_k127_4668776_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 366.0
HFD1_k127_4668776_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006781 298.0
HFD1_k127_4668776_3 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000319 276.0
HFD1_k127_4668776_4 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000000000000007273 229.0
HFD1_k127_4668776_5 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000001888 187.0
HFD1_k127_4668776_6 ASCH - - - 0.0000000000000000000000000000000008123 132.0
HFD1_k127_4681541_0 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 550.0
HFD1_k127_4681541_1 Protein kinase domain K08282,K11916,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 445.0
HFD1_k127_4681541_2 COG0518 GMP synthase - Glutamine amidotransferase domain K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001132 261.0
HFD1_k127_4681541_3 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K11890,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000002421 214.0
HFD1_k127_4681541_4 POTRA domain, ShlB-type - - - 0.00000000000000000000000000000000000000000000000001407 203.0
HFD1_k127_4681541_5 Thioredoxin K05838 - - 0.000000000000000000000000000000000000000002053 167.0
HFD1_k127_4681541_6 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000003169 124.0
HFD1_k127_4681541_7 - - - - 0.00000000000000000000003726 110.0
HFD1_k127_4681541_8 Forkhead associated domain - - - 0.000000000009469 71.0
HFD1_k127_4681541_9 - - - - 0.000000002929 60.0
HFD1_k127_4681823_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 413.0
HFD1_k127_4681823_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 383.0
HFD1_k127_4681823_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000005265 173.0
HFD1_k127_4681823_3 GMC oxidoreductase - - - 0.000000000000000000000001078 117.0
HFD1_k127_4696948_0 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 616.0
HFD1_k127_4696948_1 NAD(P) transhydrogenase beta subunit K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 510.0
HFD1_k127_4696948_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008147 432.0
HFD1_k127_4696948_3 Phospholipase D. Active site motifs. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009288 419.0
HFD1_k127_4696948_4 phytanoyl-CoA dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009798 356.0
HFD1_k127_4696948_5 glucosamine-6-phosphate deaminase activity K02564 GO:0003674,GO:0003824,GO:0004342,GO:0006040,GO:0006041,GO:0006043,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0009056,GO:0009405,GO:0009607,GO:0016787,GO:0016853,GO:0016860,GO:0016861,GO:0019239,GO:0030447,GO:0036180,GO:0040007,GO:0044182,GO:0044419,GO:0046348,GO:0050896,GO:0051704,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.99.6 0.00000000000000000000000000000000000000000000000002485 184.0
HFD1_k127_4696948_6 proteolysis - - - 0.0000000000000000000000000000000000000000000003269 179.0
HFD1_k127_4696948_7 NADP transhydrogenase K00324 - 1.6.1.2 0.00000000000000000001072 96.0
HFD1_k127_4696948_8 Lanthionine synthetase C-like protein - - - 0.0000000000000000002863 99.0
HFD1_k127_4730329_0 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs K11177 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016903,GO:0030151,GO:0033554,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114 1.17.1.4 2.32e-295 925.0
HFD1_k127_4730329_1 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000594 245.0
HFD1_k127_4730329_2 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.0000000000000000000000000000000000007555 141.0
HFD1_k127_4730431_0 Belongs to the beta-ketoacyl-ACP synthases family - - - 3.652e-214 681.0
HFD1_k127_4730431_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019538,GO:0022411,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032984,GO:0034641,GO:0034645,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 1.12e-197 623.0
HFD1_k127_4730431_2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 490.0
HFD1_k127_4730431_3 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000145 231.0
HFD1_k127_4730431_4 dehydratase - - - 0.00000000000000000000000000000000000000001169 159.0
HFD1_k127_4730431_5 cheY-homologous receiver domain - - - 0.00000000000000000000000000002521 121.0
HFD1_k127_4730431_6 Transglutaminase-like superfamily - - - 0.00000000000000008608 92.0
HFD1_k127_4754707_0 acetyl-coa acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009549 546.0
HFD1_k127_4754707_1 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 502.0
HFD1_k127_4754707_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 349.0
HFD1_k127_4754707_3 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000001338 204.0
HFD1_k127_4754707_4 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.00000000000000000000000000000000000000000000000000000429 205.0
HFD1_k127_4754707_5 Domain of unknown function (DUF4397) - - - 0.0000000000000000000000000000000004914 147.0
HFD1_k127_4754707_6 Domain of unknown function (DUF4397) - - - 0.0000000000000000000000000001848 130.0
HFD1_k127_4754707_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000001518 70.0
HFD1_k127_4759476_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 519.0
HFD1_k127_4759476_1 COG0714 MoxR-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 486.0
HFD1_k127_4759476_10 phage shock protein C K03973 - - 0.00000000000000007147 90.0
HFD1_k127_4759476_11 Phage shock protein B K03970 - - 0.0000000000000001894 81.0
HFD1_k127_4759476_12 MFS transporter - - - 0.000001934 57.0
HFD1_k127_4759476_14 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription K03969 GO:0003674,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0008289,GO:0009266,GO:0009271,GO:0009408,GO:0009605,GO:0009607,GO:0009615,GO:0009628,GO:0009889,GO:0009898,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019897,GO:0019898,GO:0031234,GO:0031323,GO:0031326,GO:0042802,GO:0043167,GO:0043168,GO:0043207,GO:0043433,GO:0044092,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0050896,GO:0051090,GO:0051171,GO:0051252,GO:0051704,GO:0051707,GO:0060187,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0098552,GO:0098562,GO:0098586,GO:1903506,GO:2000112,GO:2001141 - 0.0004132 44.0
HFD1_k127_4759476_2 protein conserved in bacteria K09989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 468.0
HFD1_k127_4759476_3 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 297.0
HFD1_k127_4759476_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001574 274.0
HFD1_k127_4759476_5 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0033890,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000721 271.0
HFD1_k127_4759476_6 Belongs to the UPF0260 family K09160 - - 0.0000000000000000000000000000000000000000000000000000001905 201.0
HFD1_k127_4759476_7 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000004918 180.0
HFD1_k127_4759476_8 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000001638 146.0
HFD1_k127_4759476_9 YcgL domain-containing protein K09902 - - 0.000000000000000002046 87.0
HFD1_k127_4792090_0 PFAM Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000005606 244.0
HFD1_k127_4792090_1 Protein of unknown function (DUF2089) - - - 0.00000000000000000004961 96.0
HFD1_k127_4792090_2 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.000115 54.0
HFD1_k127_4805585_0 Sodium proton antiporter, NhaD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 580.0
HFD1_k127_4805585_1 class II (D K K01876,K09759,K22503 - 6.1.1.12,6.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 427.0
HFD1_k127_4805585_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001213 249.0
HFD1_k127_4805585_3 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.00000000000000000000000000000000000000000000000000000000000001261 236.0
HFD1_k127_4830075_0 Phosphoglucomutase K01835 GO:0000271,GO:0003674,GO:0003824,GO:0004614,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005996,GO:0006006,GO:0006012,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0016868,GO:0019318,GO:0019320,GO:0019388,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0055114,GO:0071704,GO:1901575,GO:1901576 5.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 445.0
HFD1_k127_4830075_1 Iron/manganese superoxide dismutases, alpha-hairpin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004867 249.0
HFD1_k127_4830075_2 Glycine zipper 2TM domain K04062 - - 0.00000000001729 66.0
HFD1_k127_4830075_3 - - - - 0.00002454 50.0
HFD1_k127_4843406_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1416.0
HFD1_k127_4843406_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000216 282.0
HFD1_k127_4843406_2 Ribonucleotide reductase, small chain K00526 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000001066 244.0
HFD1_k127_4850890_0 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 365.0
HFD1_k127_4850890_1 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 317.0
HFD1_k127_4850890_2 acyl-CoA thioesterase K10805 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001751 264.0
HFD1_k127_4850890_3 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002853 246.0
HFD1_k127_4850890_4 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000000000000000000001183 182.0
HFD1_k127_4850890_5 - - - - 0.0000000000001899 76.0
HFD1_k127_4850890_6 - - - - 0.0007678 48.0
HFD1_k127_4851023_0 FAD linked oxidase K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001565 273.0
HFD1_k127_4851023_1 COG0044 Dihydroorotase and related cyclic amidohydrolases K01464,K01465 - 3.5.2.2,3.5.2.3 0.000000000000000000000000000000000001097 152.0
HFD1_k127_4851023_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000001048 130.0
HFD1_k127_4851023_3 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000000001327 79.0
HFD1_k127_4859014_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 1.003e-225 721.0
HFD1_k127_4859014_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 579.0
HFD1_k127_4859014_10 Protein phosphatase 2C - - - 0.000000000000000000000000000000000000000000000000000002995 199.0
HFD1_k127_4859014_11 COG1668 ABC-type Na efflux pump, permease component K01992 - - 0.000000000000000000000000000000000000000006446 173.0
HFD1_k127_4859014_12 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000001409 155.0
HFD1_k127_4859014_13 Protein of unknown function (DUF1244) K09948 - - 0.000000000000000000000000000000000000005496 151.0
HFD1_k127_4859014_14 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000000000000000000000217 146.0
HFD1_k127_4859014_15 PFAM pentapeptide repeat protein K18555 - - 0.0000000000000000000000000004815 123.0
HFD1_k127_4859014_16 FtsX-like permease family K02004 - - 0.00000000002669 65.0
HFD1_k127_4859014_2 membrane protein, terc - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 306.0
HFD1_k127_4859014_3 Belongs to the UPF0176 family K07146 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 311.0
HFD1_k127_4859014_4 Domain of unknown function (DUF4162) K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003321 282.0
HFD1_k127_4859014_5 ATPases associated with a variety of cellular activities K02003 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000129 254.0
HFD1_k127_4859014_6 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004108 251.0
HFD1_k127_4859014_7 signal peptide processing K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000006274 229.0
HFD1_k127_4859014_8 COG2755 Lysophospholipase L1 and related esterases K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000003158 223.0
HFD1_k127_4859014_9 FKBP-type peptidyl-prolyl isomerase K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000003357 211.0
HFD1_k127_4864727_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 514.0
HFD1_k127_4864727_1 Transferase K02527 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 403.0
HFD1_k127_4864727_2 type I secretion outer membrane protein, TolC K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 313.0
HFD1_k127_4864727_3 oxidoreductase() - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002508 254.0
HFD1_k127_4864727_4 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0005488,GO:0005506,GO:0008081,GO:0008150,GO:0008198,GO:0009987,GO:0016043,GO:0016787,GO:0016788,GO:0042545,GO:0042578,GO:0043167,GO:0043169,GO:0045229,GO:0046872,GO:0046914,GO:0071554,GO:0071555,GO:0071840 3.1.4.53 0.00000000000000000000000000000000000000000000008902 178.0
HFD1_k127_4864727_5 Protein of unknown function (DUF1249) K09920 - - 0.000000000000000000000000000000002579 134.0
HFD1_k127_4873712_0 homoserine kinase activity K02204 - 2.7.1.39 4.791e-287 915.0
HFD1_k127_4873712_1 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 523.0
HFD1_k127_4874817_0 Luciferase-like monooxygenase - - - 1.994e-206 649.0
HFD1_k127_4874817_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 377.0
HFD1_k127_4874817_2 Sir2 family K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008972 332.0
HFD1_k127_4874817_3 Thioesterase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 321.0
HFD1_k127_4874817_4 AsmA family K07290 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 340.0
HFD1_k127_4874817_5 2-hydroxychromene-2-carboxylate isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001461 244.0
HFD1_k127_4874817_6 Protein containing von Willebrand factor type A (VWA) domain K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000001869 243.0
HFD1_k127_4874817_7 - - - - 0.000000000000000001156 90.0
HFD1_k127_4874817_8 Fatty acid cis/trans isomerase (CTI) - - - 0.00000000005825 64.0
HFD1_k127_4877363_0 Sulfatase - - - 5.338e-228 715.0
HFD1_k127_4877363_1 COG3288 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 505.0
HFD1_k127_4877363_10 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000003829 144.0
HFD1_k127_4877363_11 Protein of unknown function (DUF3445) - - - 0.0000000000000000000000000000000006078 144.0
HFD1_k127_4877363_12 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000003457 137.0
HFD1_k127_4877363_13 dehydratase - - - 0.0000000000000000000000000000004065 134.0
HFD1_k127_4877363_15 HD domain - - - 0.00000003851 60.0
HFD1_k127_4877363_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 436.0
HFD1_k127_4877363_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 396.0
HFD1_k127_4877363_4 COG2515 1-aminocyclopropane-1-carboxylate deaminase K05396,K17950 - 4.4.1.15,4.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000719 325.0
HFD1_k127_4877363_5 Inositol monophosphatase K01092,K05602 - 3.1.3.15,3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007934 282.0
HFD1_k127_4877363_6 GAF domain-containing protein K08968 - 1.8.4.14 0.0000000000000000000000000000000000000000000000000000000000005721 214.0
HFD1_k127_4877363_7 Phenazine biosynthesis protein phzf family - - - 0.000000000000000000000000000000000000000000000000000000005029 213.0
HFD1_k127_4877363_8 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000316 204.0
HFD1_k127_4877363_9 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000009208 186.0
HFD1_k127_4882518_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 402.0
HFD1_k127_4882518_1 lysine 2,3-aminomutase K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001339 273.0
HFD1_k127_4882518_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000003457 181.0
HFD1_k127_4888832_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 383.0
HFD1_k127_4888832_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 370.0
HFD1_k127_4888832_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009839 327.0
HFD1_k127_4888832_3 Na melibiose symporter and related transporters K03292 - - 0.000000000000000000000000000000000000000000000000000000000000001488 229.0
HFD1_k127_4888832_4 Papain family cysteine protease - - - 0.00000000000000000000000000000000002257 138.0
HFD1_k127_4905554_0 cAMP biosynthetic process K00870,K12132 - 2.7.1.37,2.7.11.1 0.000000000000000000000000000000000000009448 167.0
HFD1_k127_4905554_1 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.00000000000000000000000000000003707 134.0
HFD1_k127_4905554_2 TIR domain - - - 0.0000000000000002524 94.0
HFD1_k127_4905554_3 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000003253 81.0
HFD1_k127_491428_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 471.0
HFD1_k127_491428_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 336.0
HFD1_k127_491428_2 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.000000000000000003679 86.0
HFD1_k127_492612_0 antibiotic catabolic process - - - 9.329e-253 801.0
HFD1_k127_492612_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001282 270.0
HFD1_k127_492612_2 nitrite reductase [NAD(P)H] activity - - - 0.00000000000000000000000000000000000000000000000009015 185.0
HFD1_k127_492612_3 MAPEG family - - - 0.000000000000000002092 90.0
HFD1_k127_493070_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 511.0
HFD1_k127_493070_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004544 274.0
HFD1_k127_493070_2 Na melibiose symporter and related transporters K03292 - - 0.0000000000000000000000000000000000000000000000000000005448 202.0
HFD1_k127_493070_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000007209 151.0
HFD1_k127_4972267_0 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 575.0
HFD1_k127_4972267_1 siderophore transport K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002488 269.0
HFD1_k127_4972647_0 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 6.323e-228 717.0
HFD1_k127_4972647_1 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 411.0
HFD1_k127_4976706_0 Sulfatase-modifying factor enzyme 1 K11912 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 315.0
HFD1_k127_4976706_1 1-phosphatidylinositol-4-phosphate 5-kinase activity - - - 0.000000000000000000000000000000000000000000000000002706 194.0
HFD1_k127_4985607_0 Arginine K01478 - 3.5.3.6 9.732e-212 662.0
HFD1_k127_4985607_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K13252 - 2.1.3.3,2.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 604.0
HFD1_k127_4985607_2 Reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 486.0
HFD1_k127_4985607_3 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001063 257.0
HFD1_k127_4985607_4 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000008296 214.0
HFD1_k127_4986971_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 474.0
HFD1_k127_4986971_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 400.0
HFD1_k127_4986971_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000742 263.0
HFD1_k127_4986971_3 - - - - 0.00000000000000000000000000000000000000000000000000000004845 207.0
HFD1_k127_4986971_4 GtrA-like protein - - - 0.000000000000000000000000002105 126.0
HFD1_k127_4998701_0 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 344.0
HFD1_k127_4998701_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 318.0
HFD1_k127_4998701_2 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001 283.0
HFD1_k127_4998701_3 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000003562 230.0
HFD1_k127_5004662_0 (ABC) transporter K02471 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016021,GO:0017076,GO:0030554,GO:0031224,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 6.045e-211 671.0
HFD1_k127_5004662_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01210 - 3.2.1.58 0.0000000000000000000000000000000000000000000000000000000000000000001298 232.0
HFD1_k127_5004662_2 Cupin - - - 0.00000000000000000000000000000000000000000006978 165.0
HFD1_k127_5004662_3 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000002767 166.0
HFD1_k127_5004662_4 Universal stress protein - - - 0.000000000000000000000000000000000000003659 152.0
HFD1_k127_5021551_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 623.0
HFD1_k127_5021551_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008412,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000351 207.0
HFD1_k127_5021551_2 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000008097 174.0
HFD1_k127_5021551_3 rubredoxin - - - 0.000000000000000000000000208 105.0
HFD1_k127_5021551_4 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.00000001652 56.0
HFD1_k127_5038383_0 selenium transferase K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 310.0
HFD1_k127_5038383_1 amidohydrolase K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000001715 234.0
HFD1_k127_5038383_2 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000005319 199.0
HFD1_k127_5038383_3 Psort location Cytoplasmic, score K01625 - 4.1.2.14,4.1.3.42 0.0000000000000001089 81.0
HFD1_k127_5050067_0 Glutathione S-transferase, C-terminal domain K00799,K03599 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 327.0
HFD1_k127_5050067_1 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000002525 152.0
HFD1_k127_5050067_2 RNA pseudouridylate synthase K06177 - 5.4.99.28,5.4.99.29 0.000000000000000000000000000000000006837 146.0
HFD1_k127_5050067_3 Cys/Met metabolism PLP-dependent enzyme K14287 - 2.6.1.88 0.000000000000000000004683 93.0
HFD1_k127_5050067_4 cytochrome c5 - - - 0.000000000000000000007383 99.0
HFD1_k127_5050067_5 - - - - 0.0000000000806 70.0
HFD1_k127_5050542_0 PFAM phospholipase Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 381.0
HFD1_k127_5050542_1 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005633 284.0
HFD1_k127_5050542_2 PFAM ATPase associated with various cellular activities K04748 - - 0.00000000000000000000000000000000000000000000000003531 197.0
HFD1_k127_5054887_0 serine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001213 290.0
HFD1_k127_5054887_1 Uncharacterized protein conserved in bacteria (DUF2332) - - - 0.000000000000000000000000001407 118.0
HFD1_k127_5054961_0 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000003772 267.0
HFD1_k127_5054961_1 alpha-ribazole phosphatase activity K00768,K15634 - 2.4.2.21,5.4.2.12 0.000000000000000000000000000014 122.0
HFD1_k127_5054961_2 Soluble pyridine nucleotide transhydrogenase K00322 - 1.6.1.1 0.0004192 48.0
HFD1_k127_5055645_0 Sugar (and other) transporter K07552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003492 288.0
HFD1_k127_5055645_1 PFAM Enoyl-CoA hydratase isomerase K01692,K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005289 276.0
HFD1_k127_5055645_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000009854 167.0
HFD1_k127_5055645_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000002042 119.0
HFD1_k127_5055645_4 CHAD - - - 0.000000001724 68.0
HFD1_k127_5059340_0 Domain of unknown function (DUF4478) K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 579.0
HFD1_k127_5059340_1 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 525.0
HFD1_k127_5059340_2 PFAM Alpha amylase, catalytic domain K01182,K01187,K05343 - 3.2.1.1,3.2.1.10,3.2.1.20,5.4.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008546 525.0
HFD1_k127_5059340_3 COG2133 Glucose sorbosone dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 496.0
HFD1_k127_5059340_4 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004343 271.0
HFD1_k127_5059340_5 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000000000002909 160.0
HFD1_k127_5059340_6 Transcriptional K03892 - - 0.00000000000000000000000000000004247 128.0
HFD1_k127_5059340_7 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000003424 70.0
HFD1_k127_5066145_0 Involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain K03578 - 3.6.4.13 6.32e-253 813.0
HFD1_k127_5066145_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 319.0
HFD1_k127_5066145_2 (Lipo)protein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000067 244.0
HFD1_k127_5066145_3 Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation K02485,K07315 GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0009893,GO:0010556,GO:0010604,GO:0016989,GO:0019219,GO:0019222,GO:0030162,GO:0031323,GO:0031325,GO:0031326,GO:0031647,GO:0031648,GO:0032268,GO:0032270,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0140110,GO:1903506,GO:2001141 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000005044 235.0
HFD1_k127_5066145_4 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) - - - 0.000000000000000000000000000000000000000000000000005427 185.0
HFD1_k127_5066145_5 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000001712 127.0
HFD1_k127_5066145_6 protein conserved in bacteria - - - 0.000000000000000000000000239 119.0
HFD1_k127_5070894_0 Flavin-binding monooxygenase-like - - - 2.485e-229 726.0
HFD1_k127_5070894_1 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009054 317.0
HFD1_k127_5070894_2 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002598 274.0
HFD1_k127_5070894_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000003656 177.0
HFD1_k127_5070894_4 nucleotidyltransferase activity - - - 0.00000000000000000000000000000000000001588 154.0
HFD1_k127_5070894_5 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000811 65.0
HFD1_k127_5075208_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 0.0 1505.0
HFD1_k127_5075208_1 Nudix N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002948 264.0
HFD1_k127_5075208_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000001472 187.0
HFD1_k127_5075208_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000001156 96.0
HFD1_k127_5075208_4 Protein of unknown function (DUF3135) - - - 0.000000000000005108 79.0
HFD1_k127_5075456_0 Concanavalin A-like lectin/glucanases superfamily - - - 2.684e-291 916.0
HFD1_k127_5075456_1 - - - - 1.576e-230 724.0
HFD1_k127_5075456_2 - - - - 0.000000000000000000000000000001717 121.0
HFD1_k127_5080675_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 457.0
HFD1_k127_5080675_1 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007282 347.0
HFD1_k127_5080675_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 303.0
HFD1_k127_5080675_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004885 265.0
HFD1_k127_5091634_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 2.76e-281 891.0
HFD1_k127_5091634_1 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006408 488.0
HFD1_k127_5091634_2 methyltransferase - - - 0.0000000000000000000000000000000000000000000000009278 186.0
HFD1_k127_5091634_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000001314 153.0
HFD1_k127_5091634_4 - - - - 0.000000000000000000007461 95.0
HFD1_k127_5093319_0 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 555.0
HFD1_k127_5093319_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 353.0
HFD1_k127_5093319_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 297.0
HFD1_k127_5093319_3 (ABC) transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000001739 217.0
HFD1_k127_5093319_4 Glutathione S-transferase - - - 0.0000000000000000000000000000000000000000000000009065 181.0
HFD1_k127_5097725_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 369.0
HFD1_k127_5097725_1 Bacterial transglutaminase-like N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001592 289.0
HFD1_k127_5097725_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002421 274.0
HFD1_k127_5097725_3 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001584 256.0
HFD1_k127_5100981_0 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 375.0
HFD1_k127_5100981_1 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 381.0
HFD1_k127_5100981_2 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002309 267.0
HFD1_k127_5100981_3 [2Fe-2S] binding domain - - - 0.00000000000000000000000000000000000000000000000000000006971 196.0
HFD1_k127_5100981_4 Uncharacterized protein conserved in bacteria (DUF2332) - - - 0.0000000000000000000000001683 113.0
HFD1_k127_5101279_0 ATPases associated with a variety of cellular activities K02003,K05685 - - 4.499e-279 882.0
HFD1_k127_5101279_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 451.0
HFD1_k127_5101279_2 HlyD family secretion protein K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 400.0
HFD1_k127_5101279_3 histidinol phosphate phosphatase HisJ family K04486 - 3.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002061 283.0
HFD1_k127_5101279_4 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005394 291.0
HFD1_k127_5101279_5 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000001948 123.0
HFD1_k127_5101320_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 535.0
HFD1_k127_5101320_1 Mechanosensitive ion channel K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 336.0
HFD1_k127_5106766_0 Binding-protein-dependent transport system inner membrane component K13895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 484.0
HFD1_k127_5106766_1 transport system, permease component K13894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009399 473.0
HFD1_k127_5106766_2 Alpha beta hydrolase - - - 0.00000000000000000000000000000000006087 137.0
HFD1_k127_5116301_0 O-acetylhomoserine sulfhydrylase K01740 - 2.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000497 243.0
HFD1_k127_5116301_1 Tyrosine phosphatase family K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000003061 189.0
HFD1_k127_5116301_2 membrane - - - 0.00000000000000000000001515 100.0
HFD1_k127_5153314_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1046.0
HFD1_k127_5153314_1 phosphate starvation-inducible protein PhoH K06217 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 447.0
HFD1_k127_5153314_2 Transfers the fatty acyl group on membrane lipoproteins K03820 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016021,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 443.0
HFD1_k127_5153314_3 Transporter associated domain K06189 GO:0001897,GO:0001906,GO:0001907,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009405,GO:0009987,GO:0016020,GO:0019835,GO:0019836,GO:0031640,GO:0035821,GO:0044003,GO:0044004,GO:0044179,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 344.0
HFD1_k127_5153314_4 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 304.0
HFD1_k127_5153314_5 DNA polymerase III, delta subunit K02340 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000001005 249.0
HFD1_k127_5153314_6 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000001068 183.0
HFD1_k127_5153314_7 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000001446 183.0
HFD1_k127_5153314_8 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000002376 137.0
HFD1_k127_5153314_9 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.00000000004143 70.0
HFD1_k127_5181930_0 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 - - 1.98e-251 795.0
HFD1_k127_5181930_1 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 556.0
HFD1_k127_5181930_2 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000000000004485 158.0
HFD1_k127_5181930_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000000005158 145.0
HFD1_k127_518223_0 metal-dependent hydrolase of the TIM-barrel fold K07046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001903 259.0
HFD1_k127_518223_1 AAA domain K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000003681 200.0
HFD1_k127_518223_2 Belongs to the GST superfamily K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000003207 190.0
HFD1_k127_518223_3 HAD-hyrolase-like K20862 - 3.1.3.102,3.1.3.104 0.000000000000000000000000000000000000000009483 161.0
HFD1_k127_518223_4 Cytidylate kinase - - - 0.000000000000000000000000000000000000004139 153.0
HFD1_k127_518223_5 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281 - 3.5.1.19 0.00000000000000000000000000001734 118.0
HFD1_k127_518223_6 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000007666 115.0
HFD1_k127_518223_7 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000006955 113.0
HFD1_k127_518223_8 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000009095 108.0
HFD1_k127_518223_9 Protein of unknown function (DUF861) - - - 0.00000000001332 75.0
HFD1_k127_519463_0 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 551.0
HFD1_k127_519463_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 498.0
HFD1_k127_519463_2 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 434.0
HFD1_k127_519463_3 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 383.0
HFD1_k127_519463_4 SMP-30 Gluconolaconase K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 362.0
HFD1_k127_519463_5 Thiolase, C-terminal domain - - - 0.000000000000000008475 83.0
HFD1_k127_5198268_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363 - 4.693e-301 937.0
HFD1_k127_5198268_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 GO:0000819,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0022402,GO:0030541,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0098813,GO:0140097,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 436.0
HFD1_k127_5200073_0 isoleucyl-tRNA aminoacylation K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 515.0
HFD1_k127_5200073_1 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 301.0
HFD1_k127_5200073_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007094 258.0
HFD1_k127_5200073_3 Alpha beta hydrolase - - - 0.00000000001631 66.0
HFD1_k127_5200165_0 Sulfatase K01130 - 3.1.6.1 0.0 1452.0
HFD1_k127_5200165_1 HupE / UreJ protein - - - 0.0000005439 53.0
HFD1_k127_5200165_2 - - - - 0.0000007529 52.0
HFD1_k127_520505_0 Protein of unknown function (DUF3604) - - - 9.587e-239 748.0
HFD1_k127_520505_1 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 405.0
HFD1_k127_520505_2 PPIC-type PPIASE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 365.0
HFD1_k127_520505_3 Protein of unknown function (DUF3604) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007319 318.0
HFD1_k127_520505_4 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009769 274.0
HFD1_k127_520505_5 s cog2930 - - - 0.000000000000000000000000000000000000000000000000000000000000000001559 232.0
HFD1_k127_520505_6 HupE / UreJ protein K03192 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000001007 245.0
HFD1_k127_520505_7 Putative phosphatase (DUF442) - - - 0.000000000000000000000000000000000000000003408 161.0
HFD1_k127_520505_8 HupE / UreJ protein - - - 0.00000000000000000000003479 112.0
HFD1_k127_5209326_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1105.0
HFD1_k127_5209326_1 ROK family K00847 - 2.7.1.4 0.00000000000000000000000005318 109.0
HFD1_k127_5214284_0 Belongs to the TPP enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005546 523.0
HFD1_k127_5214284_1 Glutathione-dependent formaldehyde-activating - - - 0.0001348 45.0
HFD1_k127_5226109_0 helix_turn_helix, arabinose operon control protein K13652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 313.0
HFD1_k127_5226109_1 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007994 253.0
HFD1_k127_5242622_0 Cytochrome c-type biogenesis protein K02198 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 611.0
HFD1_k127_5242622_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678 - 0.000000000000000000000000000000000000000000000000000000000000000000000005278 246.0
HFD1_k127_5242622_2 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015886,GO:0016020,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0051179,GO:0051181,GO:0051234,GO:0065003,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097159,GO:0098552,GO:0098567,GO:1901363,GO:1901564,GO:1901678 - 0.000000000000000000000000000000000000000000000004068 177.0
HFD1_k127_5242622_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678 - 0.00000000442 66.0
HFD1_k127_524383_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11076 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 417.0
HFD1_k127_524383_1 Putrescine transport system permease K11075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 380.0
HFD1_k127_524383_2 PFAM binding-protein-dependent transport systems inner membrane component K11070,K11074 - - 0.00000000000000000000002825 104.0
HFD1_k127_524383_3 Required for the activity of the bacterial periplasmic transport system of putrescine K11069 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0019808,GO:0019809,GO:0019810,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0051179,GO:0051234,GO:0070405,GO:0071702,GO:0071705 - 0.00000003855 57.0
HFD1_k127_526754_0 Signal Transduction Histidine Kinase K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 419.0
HFD1_k127_526754_1 Protein of unknown function (DUF692) K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 339.0
HFD1_k127_526754_2 Putative DNA-binding domain - - - 0.00000000000000000000000000000000000554 146.0
HFD1_k127_526754_3 DoxX K15977 - - 0.000000000000000000000000000003639 126.0
HFD1_k127_526754_4 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000412 76.0
HFD1_k127_526754_5 Predicted integral membrane protein (DUF2282) - - - 0.0000000001803 62.0
HFD1_k127_5281575_0 response regulator K02483,K07663 - - 0.00000000000000000000000000000000000000000000000000000000008163 212.0
HFD1_k127_5281575_1 TIGRFAM Nicotinamide mononucleotide transporter PnuC K03811 - - 0.00000000000000000000000000000000004305 139.0
HFD1_k127_5288777_0 ABC-type multidrug transport system ATPase and permease K06147,K06148 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 391.0
HFD1_k127_5288777_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 345.0
HFD1_k127_5288777_2 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 310.0
HFD1_k127_5288777_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 301.0
HFD1_k127_5288777_4 Carboxylesterase family K03929 - - 0.0000000000000005499 79.0
HFD1_k127_5293117_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 1.307e-315 977.0
HFD1_k127_5293117_1 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483 - 1.14.14.9 1.125e-232 728.0
HFD1_k127_5293117_2 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000002044 211.0
HFD1_k127_5293425_0 ABC-2 family transporter protein K01992 - - 0.0 1075.0
HFD1_k127_5293425_1 COG1131 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 348.0
HFD1_k127_5293425_2 PFAM Cys Met metabolism - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008084 304.0
HFD1_k127_5293425_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009394 310.0
HFD1_k127_5293425_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002715 265.0
HFD1_k127_5293425_5 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000003421 248.0
HFD1_k127_5293425_6 NnrU protein - - - 0.0000000000000000000000000000000000000000000000007459 183.0
HFD1_k127_5293425_7 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000000000000000000000003723 148.0
HFD1_k127_5295242_0 OmpA family - - - 1.007e-289 918.0
HFD1_k127_5295242_1 domain protein - - - 2.193e-278 877.0
HFD1_k127_5296011_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 603.0
HFD1_k127_5296011_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006629,GO:0006725,GO:0006793,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009225,GO:0009226,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0018130,GO:0019134,GO:0019438,GO:0030203,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0042546,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046872,GO:0055086,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 517.0
HFD1_k127_5296011_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000000000000006823 175.0
HFD1_k127_5303105_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA - - - 4.51e-214 707.0
HFD1_k127_5303105_1 PFAM heat shock protein DnaJ K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 463.0
HFD1_k127_5303105_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 294.0
HFD1_k127_5303105_3 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002151 273.0
HFD1_k127_5303105_4 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000000000003069 184.0
HFD1_k127_5303105_5 Sugar (and other) transporter K08178 - - 0.000000000000000000000000000000000001107 156.0
HFD1_k127_5303105_6 Protein of unknown function (DUF3667) - - - 0.0000000000000000000000000000000005217 148.0
HFD1_k127_5303105_7 PFAM MaoC like domain - - - 0.00000000000000000000000000000002103 137.0
HFD1_k127_5303105_8 MerR HTH family regulatory protein K18997 - - 0.00000000000000000000000000002529 130.0
HFD1_k127_5303105_9 Endoribonuclease L-PSP - - - 0.0000000000000000000009274 95.0
HFD1_k127_5308338_0 Rieske 2Fe-2S - - - 2.311e-207 662.0
HFD1_k127_5308338_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001267 273.0
HFD1_k127_5308338_2 Protein of unknown function (DUF3309) - - - 0.0000000000000000000004673 96.0
HFD1_k127_5314345_0 COG1960 Acyl-CoA dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007081 484.0
HFD1_k127_5314345_1 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000005249 193.0
HFD1_k127_5314345_2 Domain of unknown function (DUF1330) - - - 0.00004625 55.0
HFD1_k127_5314345_3 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00006493 48.0
HFD1_k127_5319432_0 Ammonium Transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 579.0
HFD1_k127_5319432_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 339.0
HFD1_k127_5319432_2 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000002948 227.0
HFD1_k127_5319432_3 Luciferase-like monooxygenase - - - 0.0000007077 60.0
HFD1_k127_5332541_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 512.0
HFD1_k127_5332541_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 491.0
HFD1_k127_5333026_0 EXOIII K02342,K14159 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 308.0
HFD1_k127_5333026_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000009793 213.0
HFD1_k127_5333026_2 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding K03426 GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0033554,GO:0034641,GO:0035529,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.22 0.0000000000000000000000000000000000000003801 155.0
HFD1_k127_5333026_3 COG0500 SAM-dependent methyltransferases - - - 0.00000000000000000000002925 105.0
HFD1_k127_5333028_0 mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth K15738 - - 6.389e-217 690.0
HFD1_k127_5333028_1 DNA helicase K03654 - 3.6.4.12 2.526e-197 624.0
HFD1_k127_5333028_2 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 364.0
HFD1_k127_5333028_3 COG0514 Superfamily II DNA helicase K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000001872 181.0
HFD1_k127_5333028_4 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000111 75.0
HFD1_k127_5334159_0 regulatory protein LuxR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 290.0
HFD1_k127_5334159_1 PFAM FAD linked oxidase domain protein K00803 - 2.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000002683 255.0
HFD1_k127_5334159_2 Flavoprotein involved in K transport K03379 - 1.14.13.22 0.0000000000000000000000000000000000000000000000000000000000000000258 228.0
HFD1_k127_5334159_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000225 202.0
HFD1_k127_5334159_4 YjbR - - - 0.0000000000000000000000000000000000000000000000001917 181.0
HFD1_k127_5334159_5 - - - - 0.0000000000000004907 90.0
HFD1_k127_5335206_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 475.0
HFD1_k127_5335206_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 323.0
HFD1_k127_5335206_2 monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001504 283.0
HFD1_k127_5335206_3 short-chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001031 261.0
HFD1_k127_5335206_4 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000001701 198.0
HFD1_k127_5335206_5 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000001006 188.0
HFD1_k127_533665_0 Ring hydroxylating alpha subunit (catalytic domain) K22443 - 1.14.13.239 0.00000000000000000000000000000000000000000000000000000000000000000000006367 253.0
HFD1_k127_533665_1 synthase K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000008197 213.0
HFD1_k127_533665_2 - - - - 0.0000000000000000000000000000000002256 137.0
HFD1_k127_533665_3 MAPEG family - - - 0.00000000000000000000000003542 113.0
HFD1_k127_534203_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 590.0
HFD1_k127_534203_1 COG0643 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 407.0
HFD1_k127_534203_2 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 330.0
HFD1_k127_534203_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000007973 178.0
HFD1_k127_534203_4 chemotaxis signal transduction protein K06598 - - 0.000000000000000000008013 98.0
HFD1_k127_534203_5 transketolase activity - - - 0.00004587 46.0
HFD1_k127_5347477_0 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 388.0
HFD1_k127_5347477_1 Lipoprotein K04754 - - 0.0000000000000000000000000143 123.0
HFD1_k127_5347477_2 COG0332 3-oxoacyl- acyl-carrier-protein synthase III K16872 - 2.3.1.207 0.000000000002186 66.0
HFD1_k127_5358478_0 PFAM Acyl-CoA dehydrogenase, C-terminal domain, Acyl-CoA dehydrogenase, middle domain, Acyl-CoA dehydrogenase, N-terminal domain - - - 1.298e-198 625.0
HFD1_k127_5358478_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 555.0
HFD1_k127_5358478_10 Protein of unknown function (DUF3307) - - - 0.00000000000000000000000001984 111.0
HFD1_k127_5358478_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 460.0
HFD1_k127_5358478_3 Glutathione S-Transferase K00799,K11209 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 283.0
HFD1_k127_5358478_4 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000008531 159.0
HFD1_k127_5358478_5 - - - - 0.00000000000000000000000000000000000000001514 166.0
HFD1_k127_5358478_6 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000006624 152.0
HFD1_k127_5358478_7 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000000000000000829 146.0
HFD1_k127_5358478_8 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000313 147.0
HFD1_k127_5358478_9 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000001974 139.0
HFD1_k127_5365229_0 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 294.0
HFD1_k127_5365229_1 protein conserved in bacteria K09912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000004824 146.0
HFD1_k127_5365229_2 PFAM ABC transporter related - GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0050896 - 0.000000000000000000000000000000000002938 138.0
HFD1_k127_5385103_0 COG0793 Periplasmic protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 529.0
HFD1_k127_5385103_1 helix_turn _helix lactose operon repressor K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007447 317.0
HFD1_k127_5385103_2 Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000002961 198.0
HFD1_k127_5385103_3 dioxygenase activity K00477,K18562 - 1.14.11.18 0.00000000000000000000000000000000000000000006695 179.0
HFD1_k127_5385103_4 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.00000000000000000000002045 109.0
HFD1_k127_5393712_0 Serine aminopeptidase, S33 - GO:0000287,GO:0001676,GO:0002532,GO:0002538,GO:0002539,GO:0003008,GO:0003013,GO:0003674,GO:0003824,GO:0004301,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006725,GO:0006793,GO:0006796,GO:0006950,GO:0006952,GO:0006954,GO:0007600,GO:0008015,GO:0008150,GO:0008152,GO:0008217,GO:0009056,GO:0009810,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0015643,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016801,GO:0016803,GO:0018742,GO:0018904,GO:0019216,GO:0019218,GO:0019222,GO:0019233,GO:0019439,GO:0019752,GO:0030258,GO:0032501,GO:0032787,GO:0033559,GO:0042577,GO:0042578,GO:0042579,GO:0042592,GO:0042632,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043651,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045777,GO:0046272,GO:0046483,GO:0046839,GO:0046872,GO:0046983,GO:0048518,GO:0048878,GO:0050789,GO:0050877,GO:0050896,GO:0055088,GO:0055092,GO:0060255,GO:0062012,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090181,GO:0097176,GO:1900673,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007853 398.0
HFD1_k127_5393712_1 Serine aminopeptidase, S33 - - - 0.00000000000000000195 86.0
HFD1_k127_5395119_0 Flavin-binding monooxygenase-like - - - 1.653e-296 919.0
HFD1_k127_5395119_1 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000000000000000000000000000003288 224.0
HFD1_k127_5395119_2 enoyl-CoA hydratase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000003501 209.0
HFD1_k127_54087_0 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates K01141 GO:0000175,GO:0000287,GO:0000738,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008852,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016829,GO:0016835,GO:0016895,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0046872,GO:0051575,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 3.1.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 331.0
HFD1_k127_54087_1 transport K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006372 312.0
HFD1_k127_54087_2 abc transporter atp-binding protein K05847 GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0031460,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0072337 - 0.0000000000000000000000000000000000000000000000000000000000000002292 229.0
HFD1_k127_541085_0 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004658 281.0
HFD1_k127_541085_1 dioxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000112 233.0
HFD1_k127_541085_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000001189 244.0
HFD1_k127_5438011_0 Luciferase-like monooxygenase - - - 2.465e-205 646.0
HFD1_k127_5438011_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 319.0
HFD1_k127_5438011_2 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 320.0
HFD1_k127_5438011_3 hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008161 268.0
HFD1_k127_5438011_4 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000000000000000000000000000000000000001636 235.0
HFD1_k127_5438011_5 Serine aminopeptidase, S33 K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000346 232.0
HFD1_k127_5438011_6 Histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000001122 184.0
HFD1_k127_5476666_0 Acyl-CoA dehydrogenase, C-terminal domain K14448 - 1.3.8.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 538.0
HFD1_k127_5476666_1 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 490.0
HFD1_k127_5476666_2 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 400.0
HFD1_k127_5476666_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006825 289.0
HFD1_k127_5501968_0 Domain of unknown function (DUF3336) K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 488.0
HFD1_k127_5501968_1 PFAM FMN-dependent alpha-hydroxy acid dehydrogenase K00101,K00104 - 1.1.2.3,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 417.0
HFD1_k127_5501968_2 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 365.0
HFD1_k127_5501968_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000004529 171.0
HFD1_k127_5507836_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 1.498e-282 888.0
HFD1_k127_5507836_1 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 460.0
HFD1_k127_5507836_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 311.0
HFD1_k127_5507836_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007197 274.0
HFD1_k127_5507836_4 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 GO:0000270,GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006066,GO:0006629,GO:0006720,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043164,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000002781 263.0
HFD1_k127_5507836_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000002137 231.0
HFD1_k127_5507836_6 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000001931 213.0
HFD1_k127_5507836_7 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.000000000000000000000000000000000000000000000000000000188 204.0
HFD1_k127_5507836_8 Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm K06142 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000001114 60.0
HFD1_k127_5515252_0 PFAM MgtC SapB transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001084 285.0
HFD1_k127_5515252_1 - - - - 0.0000000000000000005423 100.0
HFD1_k127_5515252_2 - - - - 0.00000000000000001045 95.0
HFD1_k127_5519147_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 375.0
HFD1_k127_5519147_1 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.00000000000000000000000000000000000000000000000001592 184.0
HFD1_k127_5519147_2 Peptidoglycan polymerase that is essential for cell division K03588 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505 - 0.0000000000000000000000000043 123.0
HFD1_k127_5530581_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 327.0
HFD1_k127_5530581_1 - - - - 0.0000000000000000000000000000000000000000000000000000000001808 227.0
HFD1_k127_5531259_0 PFAM Na dependent nucleoside transporter K03317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000342 289.0
HFD1_k127_5531259_1 Belongs to the GST superfamily K11209 - - 0.000000000000000000000000000000000000054 144.0
HFD1_k127_5531259_2 Chloramphenicol phosphotransferase-like protein K18554 - - 0.000000000000000000000000000000000001104 147.0
HFD1_k127_5541734_0 Carbamoyltransferase C-terminus K00612 - - 3.227e-270 850.0
HFD1_k127_5541734_1 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006623 267.0
HFD1_k127_5541734_2 Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core K02848 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 - 0.0000000000000000000000000000000000000000000000000000000000000000000002517 255.0
HFD1_k127_5541734_3 Catalyzes the addition of the first glucose residue to the LPS core K02844 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000001782 202.0
HFD1_k127_5557115_0 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000001467 179.0
HFD1_k127_5557115_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000008191 131.0
HFD1_k127_5557115_2 GDP-mannose 4,6 dehydratase K17741 GO:0003674,GO:0003824,GO:0004029,GO:0004090,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006066,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006725,GO:0008150,GO:0008152,GO:0008202,GO:0008204,GO:0009438,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016128,GO:0016491,GO:0016614,GO:0016616,GO:0016620,GO:0016903,GO:0018455,GO:0019752,GO:0030447,GO:0031012,GO:0032787,GO:0033721,GO:0040007,GO:0042180,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043892,GO:0044107,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044421,GO:0044424,GO:0044464,GO:0046568,GO:0050896,GO:0055114,GO:0062039,GO:0062040,GO:0071704,GO:1901360,GO:1901426,GO:1901615,GO:1901700,GO:1902652 1.1.1.283 0.000000002482 66.0
HFD1_k127_5579071_0 COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ) K01955 GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0 1639.0
HFD1_k127_5579071_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 5e-324 1000.0
HFD1_k127_5579071_10 RNA-binding protein containing KH domain, possibly ribosomal protein K07574 - - 0.00000000000000000000000000151 114.0
HFD1_k127_5579071_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 550.0
HFD1_k127_5579071_3 Carbamoyl-phosphate synthetase glutamine chain K01956 GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 541.0
HFD1_k127_5579071_4 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 470.0
HFD1_k127_5579071_5 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 367.0
HFD1_k127_5579071_6 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 343.0
HFD1_k127_5579071_7 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 294.0
HFD1_k127_5579071_8 Transcription elongation factor, N-terminal K03624 GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0032784,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000001572 227.0
HFD1_k127_5579071_9 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000005781 209.0
HFD1_k127_558384_0 COG3119 Arylsulfatase A and related enzymes - - - 3.348e-234 737.0
HFD1_k127_558384_1 Domain of unknown function (DUF1794) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009591 318.0
HFD1_k127_558384_2 Conserved TM helix K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007452 282.0
HFD1_k127_558384_3 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002714 287.0
HFD1_k127_558384_4 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006267 268.0
HFD1_k127_558384_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000824 270.0
HFD1_k127_558384_6 - - - - 0.000000000000000000000000000000000000000000000000000000000003992 217.0
HFD1_k127_558384_7 phosphatase - - - 0.00000000000002255 79.0
HFD1_k127_5594533_0 Periplasmic sensor domain found in signal transduction proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009769 388.0
HFD1_k127_5594533_1 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000881 254.0
HFD1_k127_5594533_2 ChrR Cupin-like domain - - - 0.00000000000000000000000000000000000000000000000002672 186.0
HFD1_k127_5594533_3 very-long-chain-acyl-CoA dehydrogenase activity K18845 - 2.1.1.179 0.000000000000000000000000000000005479 142.0
HFD1_k127_5594533_4 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K06149 - - 0.000000000000000000000000000001627 126.0
HFD1_k127_5594533_5 universal stress protein K06149 - - 0.00000000000000000000003668 105.0
HFD1_k127_5594533_6 - - - - 0.0005502 47.0
HFD1_k127_5601771_0 Cytochrome c554 and c-prime - - - 5.598e-227 727.0
HFD1_k127_5601771_1 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006508 241.0
HFD1_k127_5625306_0 Metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 458.0
HFD1_k127_5625306_1 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000799 267.0
HFD1_k127_5625306_2 Sigma-70, region 4 - - - 0.000000000000000000000000000000000000000000000002075 181.0
HFD1_k127_5625306_3 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000000000002641 103.0
HFD1_k127_563356_0 Flavin-binding monooxygenase-like K14520 - 1.14.13.84 6.479e-218 694.0
HFD1_k127_563356_1 Aldo/keto reductase family K05882 - 1.1.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 374.0
HFD1_k127_563356_2 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 354.0
HFD1_k127_563356_3 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 361.0
HFD1_k127_563356_4 Beta-lactamase K18372 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 333.0
HFD1_k127_563356_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006147 334.0
HFD1_k127_563356_6 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000366 274.0
HFD1_k127_563356_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000001299 117.0
HFD1_k127_563356_8 Transcription factor zinc-finger K09981 - - 0.00000293 53.0
HFD1_k127_5646129_0 COG4796 Type II secretory pathway, component HofQ K02507,K02666 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 424.0
HFD1_k127_5646129_1 Pilus assembly protein K02664 - - 0.00000000000000000000000000000000000000000000000000000000000000003801 228.0
HFD1_k127_5646129_2 Pilus assembly protein, PilP K02665 - - 0.00000000000000000000000000000000000000000000000003374 187.0
HFD1_k127_5648390_0 acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000001129 174.0
HFD1_k127_5648390_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000002717 171.0
HFD1_k127_5669846_0 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 529.0
HFD1_k127_5674299_0 Aldehyde dehydrogenase family K00154,K22445 - 1.2.1.68,1.2.99.10 2.933e-194 612.0
HFD1_k127_5674299_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006538 520.0
HFD1_k127_5674299_2 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009276 305.0
HFD1_k127_5674299_3 protein conserved in bacteria - GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000717 173.0
HFD1_k127_5674299_4 Domain of unknown function (DUF4156) - - - 0.0007747 43.0
HFD1_k127_568873_0 COG0332 3-oxoacyl- acyl-carrier-protein synthase III K16872 - 2.3.1.207 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009024 492.0
HFD1_k127_568873_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 385.0
HFD1_k127_568873_2 COG1622 Heme copper-type cytochrome quinol oxidases, subunit 2 K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000006999 189.0
HFD1_k127_568873_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000001567 79.0
HFD1_k127_571302_0 Belongs to the GST superfamily K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008914 398.0
HFD1_k127_571302_1 Alpha/beta hydrolase family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009728 363.0
HFD1_k127_571302_2 PFAM Tannase and feruloyl esterase - - - 0.0000000000005289 74.0
HFD1_k127_5744605_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1525.0
HFD1_k127_5744605_1 Papain family cysteine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 468.0
HFD1_k127_5744605_2 Protein of unknown function (DUF1090) - - - 0.000001276 57.0
HFD1_k127_5759238_0 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 338.0
HFD1_k127_5759238_1 HIT domain - - - 0.000000000000000000000000000000000001067 154.0
HFD1_k127_5783975_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 3.5e-323 1011.0
HFD1_k127_5783975_1 DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000728 101.0
HFD1_k127_5790670_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 517.0
HFD1_k127_5790670_1 transporter K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 360.0
HFD1_k127_5790670_2 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.0000000000000000000000000000000000000000000000004295 185.0
HFD1_k127_5790670_3 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000005804 180.0
HFD1_k127_5797200_0 CreA protein K05805 - - 0.0000000000000000000000000000000000000000000000000000000000000000006735 237.0
HFD1_k127_5797200_1 Protein of unknown function (DUF1415) K09941 - - 0.0000000000000000000000000000000000000000000000000000000000001424 220.0
HFD1_k127_5797200_2 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000006093 205.0
HFD1_k127_5797200_4 SnoaL-like polyketide cyclase - - - 0.000000003464 64.0
HFD1_k127_5805695_0 NADP-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 475.0
HFD1_k127_5805695_1 CoA-transferase family III K07749,K08298 - 2.8.3.16,2.8.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 432.0
HFD1_k127_5805695_2 Mate efflux family protein K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 375.0
HFD1_k127_5805695_3 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 300.0
HFD1_k127_5805695_4 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000006489 180.0
HFD1_k127_5805695_5 Methyltransferase domain - - - 0.00000000000000000004951 91.0
HFD1_k127_5810028_0 Esterase-like activity of phytase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008173 475.0
HFD1_k127_5810028_1 Belongs to the GST superfamily K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 311.0
HFD1_k127_5810028_2 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 290.0
HFD1_k127_5810028_3 Alpha/beta hydrolase family K18092 - - 0.0000000005824 68.0
HFD1_k127_581909_0 Gamma-glutamyltranspeptidase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 293.0
HFD1_k127_581909_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000008831 106.0
HFD1_k127_5821281_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 589.0
HFD1_k127_5821281_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K18334 - 4.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 584.0
HFD1_k127_5821281_2 2-hydroxychromene-2-carboxylate isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 321.0
HFD1_k127_5821281_3 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000001021 210.0
HFD1_k127_5821281_4 Thioredoxin-like - - - 0.00000000000000000000000000000000000000001078 170.0
HFD1_k127_5821281_5 Enoyl-(Acyl carrier protein) reductase K18335 - - 0.000000000000001741 78.0
HFD1_k127_5821281_6 - - - - 0.000000001481 62.0
HFD1_k127_5824588_0 Acyl-CoA dehydrogenase, C-terminal domain K09456 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003995,GO:0005488,GO:0005515,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008470,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016491,GO:0016627,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0033554,GO:0042802,GO:0043565,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0055114,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 607.0
HFD1_k127_5824588_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 574.0
HFD1_k127_5844098_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481,K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008718 593.0
HFD1_k127_5844098_1 COG0642 Signal transduction histidine kinase K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 415.0
HFD1_k127_5844098_2 COG4970 Tfp pilus assembly protein FimT K08084 - - 0.000000000000211 76.0
HFD1_k127_5860469_0 in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor' K14260 GO:0003674,GO:0003824,GO:0004021,GO:0005488,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0019842,GO:0030170,GO:0030632,GO:0032787,GO:0033554,GO:0036094,GO:0042221,GO:0042851,GO:0042852,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0046677,GO:0047635,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.2,2.6.1.66 4.057e-201 636.0
HFD1_k127_5860469_1 Fad dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008212 413.0
HFD1_k127_5860469_2 ATP-NAD kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 341.0
HFD1_k127_5860469_3 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.000000000000000000000000000000000000005008 150.0
HFD1_k127_5860469_4 - - - - 0.00000000000000000000000000000000000008069 147.0
HFD1_k127_5860469_5 Elongation factor P hydroxylase K09906 GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0017185,GO:0018126,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0055114,GO:0071704,GO:0072580,GO:1901260,GO:1901564 - 0.0000000000000000000000000000000005008 138.0
HFD1_k127_5860469_6 Sulfur carrier protein TusA K04085 - - 0.00000000000000000004174 92.0
HFD1_k127_5860469_7 - - - - 0.00000000007355 74.0
HFD1_k127_5876840_0 family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 404.0
HFD1_k127_5876840_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000001028 174.0
HFD1_k127_5876840_2 xanthine catabolic process K00106,K00157 - 1.17.1.4,1.17.3.2,1.2.3.1 0.00000000005293 64.0
HFD1_k127_5881418_0 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000171 256.0
HFD1_k127_5881418_1 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000005003 256.0
HFD1_k127_5881418_2 Bacterial regulatory proteins, tetR family - - - 0.00000000002739 74.0
HFD1_k127_5881418_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00007612 53.0
HFD1_k127_5891745_0 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 458.0
HFD1_k127_5891745_1 Domain of Unknown Function (DUF1259) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 361.0
HFD1_k127_5891745_2 ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 370.0
HFD1_k127_5891745_3 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 325.0
HFD1_k127_5891745_4 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000003299 214.0
HFD1_k127_5891745_5 Protein conserved in bacteria K09984 - - 0.00000000000000000000000000000000000000000000002524 173.0
HFD1_k127_5891745_6 Alpha beta hydrolase - - - 0.0000000004272 63.0
HFD1_k127_5897279_0 Aldehyde dehydrogenase family K00151 - 1.2.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 443.0
HFD1_k127_5897279_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000204 240.0
HFD1_k127_5897279_2 Fumarylacetoacetate (FAA) hydrolase family K02554 - 4.2.1.80 0.000000000000000000000000000000000000000000000000000000000000009564 224.0
HFD1_k127_5897279_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K14751 - - 0.000000000000000000000000000000000000000000000000000000000001721 214.0
HFD1_k127_5897279_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K14751 - - 0.0000000000000000000000000000000000000000009609 159.0
HFD1_k127_5897279_5 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000006691 110.0
HFD1_k127_590490_0 Putative amidoligase enzyme (DUF2126) - - - 3.434e-321 996.0
HFD1_k127_590490_1 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 499.0
HFD1_k127_5914857_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 397.0
HFD1_k127_5914857_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 360.0
HFD1_k127_5914857_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 356.0
HFD1_k127_5914857_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 308.0
HFD1_k127_5914857_4 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001381 271.0
HFD1_k127_5914857_5 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000009007 188.0
HFD1_k127_5919060_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 6.501e-251 779.0
HFD1_k127_5919060_1 Glutamine amidotransferase domain K22081 - 2.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 493.0
HFD1_k127_5919060_2 Conserved region in glutamate synthase K22083 - 2.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 495.0
HFD1_k127_5919060_3 GXGXG motif K22082 - 2.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 327.0
HFD1_k127_5919060_4 Belongs to the glutamate synthase family K22083 - 2.1.1.21 0.000000000000000000000000000000000000000000000000000000000000001806 219.0
HFD1_k127_5957364_0 PFAM Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000000000000000000000000000000001303 199.0
HFD1_k127_5957364_1 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000000000000000000000000002602 133.0
HFD1_k127_5957364_2 Protein of unknown function (DUF3604) - - - 0.0000000000000000000000006594 110.0
HFD1_k127_5957364_3 ABC transporter K02065 - - 0.0000000000000000007119 88.0
HFD1_k127_5957364_4 PFAM Mammalian cell entry related domain protein K02067 - - 0.0003912 43.0
HFD1_k127_5957917_0 ABC-type multidrug transport system ATPase and permease K06147 - - 1.688e-289 898.0
HFD1_k127_5957917_1 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 406.0
HFD1_k127_5957917_2 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000004596 164.0
HFD1_k127_5957917_3 - - - - 0.000000000000000000000000000001705 126.0
HFD1_k127_5973640_0 Histidine kinase K07646 - 2.7.13.3 2.763e-234 745.0
HFD1_k127_5973640_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 336.0
HFD1_k127_5998307_0 transport protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 312.0
HFD1_k127_5998307_1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002982 279.0
HFD1_k127_5998307_2 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.0000000000000000000000000000000000000000000000000000005053 195.0
HFD1_k127_5998307_3 Phenazine biosynthesis protein A/B K06893 - - 0.0000001048 63.0
HFD1_k127_6005652_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005133 496.0
HFD1_k127_6005652_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009919 412.0
HFD1_k127_6005652_2 Enoyl-CoA hydratase/isomerase K08299 - 4.2.1.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 379.0
HFD1_k127_6005652_3 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 318.0
HFD1_k127_6005652_4 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 311.0
HFD1_k127_6005652_5 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000002926 236.0
HFD1_k127_6005652_6 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000002157 197.0
HFD1_k127_6005652_7 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000001622 154.0
HFD1_k127_6005652_8 alpha-ribazole phosphatase activity K00768,K15634 - 2.4.2.21,5.4.2.12 0.0000000002008 64.0
HFD1_k127_6013955_0 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000008903 222.0
HFD1_k127_6013955_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000001199 154.0
HFD1_k127_6027051_0 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 500.0
HFD1_k127_6027051_1 TIM-barrel fold metal-dependent hydrolase - - - 0.00000000000000000000000000000000002102 147.0
HFD1_k127_6032544_0 PFAM Orn Lys Arg decarboxylase major region K01582,K01584 - 4.1.1.18,4.1.1.19 4.09e-313 976.0
HFD1_k127_6046919_0 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 425.0
HFD1_k127_6046919_1 Lanthionine synthetase C-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 424.0
HFD1_k127_6046919_2 Putative porin - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 425.0
HFD1_k127_6046919_3 TIGRFAM phosphate binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007346 417.0
HFD1_k127_6046919_4 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002378 272.0
HFD1_k127_6046919_5 PFAM Methyltransferase type 11 K00563 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008270,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.187 0.000000000000000000000000000000000000000000000000000000000002224 218.0
HFD1_k127_6046919_6 PFAM Binding-protein-dependent transport system inner membrane component K02038 - - 0.00000000000000009022 93.0
HFD1_k127_6051048_0 Lipase maturation factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 408.0
HFD1_k127_6068208_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 2.255e-212 684.0
HFD1_k127_6068208_1 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 2.953e-200 628.0
HFD1_k127_6068208_2 Bacterial virulence protein (VirJ) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 391.0
HFD1_k127_6068208_3 FAD binding domain K00480 - 1.14.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 369.0
HFD1_k127_6068208_4 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000003701 217.0
HFD1_k127_6068208_5 lipid catabolic process - - - 0.000000000000000000000000000001226 133.0
HFD1_k127_6068208_6 - - - - 0.0000000000000000000004966 112.0
HFD1_k127_6070459_0 COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain K06147,K13409 - - 3.708e-198 636.0
HFD1_k127_6070459_1 Thioesterase-like superfamily K10805 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002598 274.0
HFD1_k127_6070459_2 NADP-dependent oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000000000000861 184.0
HFD1_k127_6072896_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 5e-324 1003.0
HFD1_k127_6072896_1 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 3.127e-241 760.0
HFD1_k127_6072896_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 568.0
HFD1_k127_6072896_3 acyl-CoA transferases carnitine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001819 258.0
HFD1_k127_6072896_4 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000004456 235.0
HFD1_k127_6072896_5 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000002858 232.0
HFD1_k127_6072896_6 FKBP-type peptidyl-prolyl cis-trans K03772,K03773 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000003715 227.0
HFD1_k127_607590_0 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 508.0
HFD1_k127_607590_1 flavoprotein involved in K transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 427.0
HFD1_k127_607590_2 synthase K01719 - 4.2.1.75 0.0000000006226 62.0
HFD1_k127_6106508_0 Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007109 515.0
HFD1_k127_6106508_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0006970,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009268,GO:0009409,GO:0009628,GO:0009651,GO:0009987,GO:0010467,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043021,GO:0043023,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 378.0
HFD1_k127_6106508_2 Negative regulator of sigma E activity K03598 - - 0.00000000000000000000000000000000000000000000000000000137 202.0
HFD1_k127_6113829_0 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003114 244.0
HFD1_k127_6113829_1 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004851 240.0
HFD1_k127_6113829_2 glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich K01190 - 3.2.1.23 0.0000000000000000000000000000000000000000000000000000000000001674 223.0
HFD1_k127_6113829_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000008926 80.0
HFD1_k127_6117100_0 Major Facilitator Superfamily K13021 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 473.0
HFD1_k127_6117100_1 Belongs to the ompA family K03286 - - 0.0006156 49.0
HFD1_k127_6121890_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 593.0
HFD1_k127_6121890_1 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000000006941 202.0
HFD1_k127_6121890_2 Ribosomal protein L30p/L7e K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000007436 101.0
HFD1_k127_6121890_3 Belongs to the universal ribosomal protein uS5 family K02988 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 - 0.0000000214 55.0
HFD1_k127_6136963_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 1.424e-213 669.0
HFD1_k127_6136963_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 3.749e-196 617.0
HFD1_k127_6136963_10 COG3103 SH3 domain protein K07184 - - 0.0000000000000000000000003382 118.0
HFD1_k127_6136963_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K18456 - 3.5.4.28,3.5.4.31,3.5.4.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 440.0
HFD1_k127_6136963_3 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 335.0
HFD1_k127_6136963_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 329.0
HFD1_k127_6136963_5 Belongs to the SUA5 family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 284.0
HFD1_k127_6136963_6 Belongs to the pseudouridine synthase RsuA family K06178 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 292.0
HFD1_k127_6136963_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000411 272.0
HFD1_k127_6136963_8 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008923 246.0
HFD1_k127_6136963_9 probably involved in intracellular septation K06190 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000001206 149.0
HFD1_k127_6139026_0 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 516.0
HFD1_k127_6139026_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 385.0
HFD1_k127_6139026_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008213 285.0
HFD1_k127_6139026_3 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000001479 253.0
HFD1_k127_6139026_4 Major facilitator superfamily - - - 0.0000000003779 60.0
HFD1_k127_6152025_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 353.0
HFD1_k127_6152025_1 DEAD-box RNA helicase involved in K05592 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003727,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010468,GO:0010501,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019439,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0032268,GO:0032270,GO:0033554,GO:0033592,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034655,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043170,GO:0043487,GO:0043488,GO:0043489,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045934,GO:0046483,GO:0046700,GO:0048255,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070035,GO:0070417,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097617,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902369,GO:1902373,GO:1903311,GO:1903312,GO:2000112 3.6.4.13 0.00000000000000000000000000000000000113 144.0
HFD1_k127_6152481_0 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001634 277.0
HFD1_k127_6152481_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000008736 168.0
HFD1_k127_6152481_2 SdpI/YhfL protein family - - - 0.00000000000000000000000001316 115.0
HFD1_k127_6154599_0 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 603.0
HFD1_k127_6154599_1 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001879 278.0
HFD1_k127_6154599_2 PFAM YdjC family protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000000000000002342 213.0
HFD1_k127_6154599_3 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000001101 152.0
HFD1_k127_6154599_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000001579 144.0
HFD1_k127_6154599_5 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.00000000000000004372 90.0
HFD1_k127_6155046_0 GMC oxidoreductase K06151 - 1.1.99.3 1.096e-210 687.0
HFD1_k127_6155046_1 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007533 440.0
HFD1_k127_6155046_2 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 340.0
HFD1_k127_6155046_3 Domain of unknown function (DUF4136) - - - 0.0000000000000000000000000000000000000000000008596 172.0
HFD1_k127_6155046_4 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000001527 177.0
HFD1_k127_6156437_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 507.0
HFD1_k127_6156437_1 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 416.0
HFD1_k127_6156437_2 BNR repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 309.0
HFD1_k127_6156437_3 acetyltransferase - - - 0.00000000000000005839 87.0
HFD1_k127_6163891_0 PFAM Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 419.0
HFD1_k127_6163891_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000001179 216.0
HFD1_k127_6163891_2 - - - - 0.000000000000000000000000000000000000000000000000000000000007496 216.0
HFD1_k127_6163891_3 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000001223 218.0
HFD1_k127_6163891_4 Alpha beta hydrolase K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000000000001309 199.0
HFD1_k127_6163891_5 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000000000000000009659 159.0
HFD1_k127_6163891_6 - - - - 0.0000000000000000000000000000000003263 138.0
HFD1_k127_6163891_7 START domain - - - 0.000000000000000000000000002988 121.0
HFD1_k127_6163891_8 lipolytic protein G-D-S-L family - - - 0.0000000006852 71.0
HFD1_k127_6174479_0 PFAM General substrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 509.0
HFD1_k127_6174479_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 395.0
HFD1_k127_6174479_2 Surface antigen variable number K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 362.0
HFD1_k127_6174479_3 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 325.0
HFD1_k127_6174479_4 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002288 259.0
HFD1_k127_6174479_5 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000002027 205.0
HFD1_k127_6174479_6 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000001576 147.0
HFD1_k127_6174479_7 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000002843 94.0
HFD1_k127_6216224_0 Oxidative deamination of D-amino acids K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008781 323.0
HFD1_k127_6216224_1 Lipase maturation factor - - - 0.00000000000001075 85.0
HFD1_k127_6220015_0 Major facilitator Superfamily K08162,K08226,K16211 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 334.0
HFD1_k127_6220015_1 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000461 209.0
HFD1_k127_6220015_2 Ribosomal RNA adenine dimethylase - - - 0.0000002931 52.0
HFD1_k127_6231482_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004134 239.0
HFD1_k127_6231482_1 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000001689 145.0
HFD1_k127_6231482_2 - - - - 0.0000000000000000000000000000000000933 141.0
HFD1_k127_6231482_3 Acetyltransferase (GNAT) domain K18816 - 2.3.1.82 0.0000000000000000000000000000000001126 139.0
HFD1_k127_6231482_4 acetyltransferase - - - 0.0000000000000000000000000003171 119.0
HFD1_k127_6237947_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009383 393.0
HFD1_k127_6237947_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 383.0
HFD1_k127_6237947_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 336.0
HFD1_k127_6237947_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 300.0
HFD1_k127_6237947_4 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000005383 257.0
HFD1_k127_6237947_5 cell wall glycoprotein biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000007774 228.0
HFD1_k127_6237947_6 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000000000000000000000000000000000000000004468 214.0
HFD1_k127_6237947_7 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000002896 175.0
HFD1_k127_6237947_8 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000001008 171.0
HFD1_k127_6237947_9 protein conserved in bacteria - - - 0.00000000000000000001183 105.0
HFD1_k127_6246667_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18989 - - 0.0 1174.0
HFD1_k127_6246667_1 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000003865 179.0
HFD1_k127_6246667_2 COG2211 Na melibiose symporter and related transporters - - - 0.0000000000000000000003725 99.0
HFD1_k127_6249438_0 - - - - 0.000000000000000000000000000000000000003429 156.0
HFD1_k127_6249438_1 DNA-binding transcription factor activity - - - 0.000000000000000000001971 97.0
HFD1_k127_6249438_2 Chase2 domain - - - 0.0000000000000002337 84.0
HFD1_k127_6249438_3 Protein of unknown function (DUF3617) - - - 0.00000000009771 70.0
HFD1_k127_6249438_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0002749 50.0
HFD1_k127_625414_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 308.0
HFD1_k127_625414_1 Sugar (and other) transporter K08151 - - 0.00000000000000001384 87.0
HFD1_k127_6267555_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.768e-253 791.0
HFD1_k127_6267555_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 6.413e-231 719.0
HFD1_k127_6270555_0 COG0625 Glutathione S-transferase K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 435.0
HFD1_k127_6270555_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 350.0
HFD1_k127_6270555_2 pyridine nucleotide-disulphide oxidoreductase dimerisation - - - 0.000000000005531 71.0
HFD1_k127_6270555_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000006729 66.0
HFD1_k127_6275842_0 Biotin carboxylase - - - 2.705e-224 701.0
HFD1_k127_6275842_1 Dehydrogenase E1 component K21416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 406.0
HFD1_k127_6275842_2 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 408.0
HFD1_k127_6275842_3 COG1858 Cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 345.0
HFD1_k127_6275842_4 pfam atp-nad - - - 0.0000000000000000000000000000000000000000000000000000000000000000007442 239.0
HFD1_k127_6275842_5 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K00219,K01069 - 1.3.1.34,3.1.2.6 0.0000000000000000000000000000000000000000000000000000002288 207.0
HFD1_k127_6275842_6 Tetratricopeptide repeat - - - 0.0000006149 59.0
HFD1_k127_6289613_0 Epoxide hydrolase N terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 398.0
HFD1_k127_6289613_1 regulation of DNA-templated transcription, elongation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002378 314.0
HFD1_k127_6289613_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004348 257.0
HFD1_k127_6289613_3 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000001878 198.0
HFD1_k127_6293460_0 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009753 447.0
HFD1_k127_6293460_1 protein possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000000000000009783 177.0
HFD1_k127_6293460_2 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000001045 168.0
HFD1_k127_6293460_3 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000001653 153.0
HFD1_k127_6293460_4 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000001607 148.0
HFD1_k127_6293460_5 signal transduction protein with a C-terminal ATPase domain K08082 - 2.7.13.3 0.0001125 48.0
HFD1_k127_6293460_6 FR47-like protein - - - 0.0001278 45.0
HFD1_k127_6301172_0 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 GO:0001887,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016785,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043828,GO:0044237,GO:0044238,GO:0046483,GO:0070329,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 321.0
HFD1_k127_6301172_1 Nitrile hydratase, alpha chain - - - 0.00000000000000000000000000000000000000000000003856 171.0
HFD1_k127_6301172_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0006950,GO:0006979,GO:0008113,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016671,GO:0019538,GO:0030091,GO:0033744,GO:0036456,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0055114,GO:0071704,GO:1901564 1.8.4.11 0.000000000000000000000004276 104.0
HFD1_k127_6301172_3 Nitrile hydratase beta subunit - - - 0.00000000000000000001395 100.0
HFD1_k127_6301172_4 Sel1 domain protein repeat-containing protein K07126 - - 0.0000000003181 73.0
HFD1_k127_6301678_0 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes K00957 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0070566,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 504.0
HFD1_k127_6301678_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000496 479.0
HFD1_k127_6301678_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000005297 115.0
HFD1_k127_6325391_0 and related enzymes K11159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 546.0
HFD1_k127_6325391_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 537.0
HFD1_k127_6325391_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000002911 145.0
HFD1_k127_6325391_3 Protein of unknown function (DUF2799) - - - 0.00000000000000000000000000000004795 134.0
HFD1_k127_6325391_4 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000003102 57.0
HFD1_k127_6341126_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase K00483,K21726 - 1.14.13.166,1.14.13.29,1.14.14.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 303.0
HFD1_k127_6341126_1 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000000000000000141 212.0
HFD1_k127_6341126_2 Alpha beta hydrolase - - - 0.000000000000000000000000002795 122.0
HFD1_k127_6372506_0 Sulfate permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 559.0
HFD1_k127_6372506_1 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001286 262.0
HFD1_k127_6372506_2 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004985 251.0
HFD1_k127_6372506_3 YMGG-like Gly-zipper - - - 0.000000000000000000000000000000000000007054 151.0
HFD1_k127_6372506_4 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000001085 132.0
HFD1_k127_6372506_5 - - - - 0.0000000000000000002793 90.0
HFD1_k127_6383089_0 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 522.0
HFD1_k127_6383089_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005038 404.0
HFD1_k127_6383089_2 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000001925 228.0
HFD1_k127_6383089_3 Pectinacetylesterase - - - 0.00000000000000000000001233 107.0
HFD1_k127_6396659_0 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 582.0
HFD1_k127_6396659_1 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 355.0
HFD1_k127_6396659_2 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 340.0
HFD1_k127_6396659_4 domain, Protein - - - 0.000003749 59.0
HFD1_k127_6411902_0 Hydantoinase/oxoprolinase K01473 - 3.5.2.14 6.557e-215 687.0
HFD1_k127_6411902_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 325.0
HFD1_k127_6411902_2 Belongs to the UPF0758 family K03630 GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000009274 244.0
HFD1_k127_6411902_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 GO:0000166,GO:0003674,GO:0003824,GO:0004632,GO:0004633,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0015936,GO:0015937,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032553,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000193 180.0
HFD1_k127_6411902_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019897,GO:0019898,GO:0031224,GO:0031226,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000002345 188.0
HFD1_k127_6411902_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000001968 170.0
HFD1_k127_6411902_6 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000292 168.0
HFD1_k127_6411902_7 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000000001542 139.0
HFD1_k127_6411902_8 Multidrug transporter - - - 0.0000000000000000000000008555 108.0
HFD1_k127_6411902_9 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000003958 96.0
HFD1_k127_6415854_0 enoyl-CoA hydratase isomerase family protein - - - 0.0000000000000000000000000000000000000000000000000001108 205.0
HFD1_k127_6415854_1 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000001421 109.0
HFD1_k127_6419188_0 Proteasome subunit K01419 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 295.0
HFD1_k127_6419188_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001143 276.0
HFD1_k127_6419188_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000001381 134.0
HFD1_k127_6419188_3 Sporulation related domain K03591 - - 0.000000000001016 76.0
HFD1_k127_6458583_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 4.354e-249 783.0
HFD1_k127_6458583_1 Zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 430.0
HFD1_k127_6458583_2 dioxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001728 274.0
HFD1_k127_6470143_1 DEAD/H associated K03724 - - 0.0000000000000000000000000000000000000001052 160.0
HFD1_k127_6470143_2 Histone deacetylase domain - - - 0.00000000000000000000000000000000000005726 147.0
HFD1_k127_6470143_3 Diguanylate cyclase - - - 0.0000000000000000000000000000000000006641 156.0
HFD1_k127_6470143_4 triphosphatase activity - - - 0.00000000000000002898 90.0
HFD1_k127_6480588_0 ABC-type transport system, involved in lipoprotein release, permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008913 283.0
HFD1_k127_6480588_1 ABC transporter K02003,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000622 264.0
HFD1_k127_6480588_2 ABC-type transport system, involved in lipoprotein release, permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002109 270.0
HFD1_k127_6480588_3 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000626 262.0
HFD1_k127_6480588_4 - - - - 0.000000000000000000000000000000000000000000000000000002451 211.0
HFD1_k127_6480588_5 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000001655 136.0
HFD1_k127_6483053_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 1.183e-246 768.0
HFD1_k127_6483053_1 Acyl-CoA dehydrogenase, middle domain K00253 - 1.3.8.4 5.331e-197 622.0
HFD1_k127_6483053_2 Biotin carboxylase C-terminal domain K01968 - 6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 553.0
HFD1_k127_6495257_0 DNA polymerase K02347 - - 8.187e-229 724.0
HFD1_k127_6495257_1 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006684 336.0
HFD1_k127_6495257_2 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001041 258.0
HFD1_k127_6495257_3 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001058 254.0
HFD1_k127_6495257_4 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000002408 205.0
HFD1_k127_6503041_0 Long-chain fatty acid--CoA ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003836 250.0
HFD1_k127_6503041_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000143 233.0
HFD1_k127_6503041_2 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000005212 228.0
HFD1_k127_6503041_3 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) - - - 0.0000000000000000000000000000000000000000000000001186 183.0
HFD1_k127_6517580_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 525.0
HFD1_k127_6517580_1 RNHCP domain - - - 0.0000000000000000000000000000002255 126.0
HFD1_k127_6517580_2 - - - - 0.00000000001257 74.0
HFD1_k127_6517580_3 SMART Transport-associated and nodulation region K04065 - - 0.0000002775 53.0
HFD1_k127_6523991_0 membrane K14205 - 2.3.2.3 3.531e-219 707.0
HFD1_k127_6523991_1 maleylacetoacetate isomerase K01800 - 5.2.1.2 0.00000000000000000000000002031 110.0
HFD1_k127_6523991_2 Bacterial virulence protein (VirJ) - - - 0.000000003744 63.0
HFD1_k127_6525020_0 Glycosyl hydrolases family 32 N-terminal domain K01193 - 3.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 295.0
HFD1_k127_6525020_1 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000006211 147.0
HFD1_k127_6526784_0 acetolactate synthase K01652 - 2.2.1.6 3.479e-276 859.0
HFD1_k127_6526784_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 526.0
HFD1_k127_6526784_2 Acetolactate synthase small K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000002998 246.0
HFD1_k127_6526784_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000009097 116.0
HFD1_k127_6530453_0 - - - - 0.000000000000000000000000000000000000000000000000000000007126 209.0
HFD1_k127_6530453_1 Transcriptional regulator K13572 - - 0.0000000000000000000000000000000000000842 147.0
HFD1_k127_6530453_2 - - - - 0.000000000000000000000000000000005748 138.0
HFD1_k127_6530453_3 pyridoxamine 5'-phosphate oxidase - - - 0.00000005475 61.0
HFD1_k127_6541353_0 TrkA-N domain K03455 - - 1.037e-240 755.0
HFD1_k127_6541353_1 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 455.0
HFD1_k127_6541353_2 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 349.0
HFD1_k127_6541353_3 Shikimate dehydrogenase substrate binding domain K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000001523 249.0
HFD1_k127_6552062_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 2.409e-207 651.0
HFD1_k127_6552062_1 AFG1-like ATPase K06916 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044424,GO:0044464,GO:0051301 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 432.0
HFD1_k127_6552062_10 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000001678 114.0
HFD1_k127_6552062_11 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain K04691,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0033554,GO:0035966,GO:0035967,GO:0042221,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0051788,GO:0070011,GO:0070887,GO:0071218,GO:0071310,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564 - 0.000946 44.0
HFD1_k127_6552062_2 Stringent starvation protein A K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 308.0
HFD1_k127_6552062_3 LppC putative lipoprotein K07121 GO:0000270,GO:0003674,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003171 272.0
HFD1_k127_6552062_4 Cytochrome C1 family K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001016 273.0
HFD1_k127_6552062_5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000008323 256.0
HFD1_k127_6552062_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000002223 220.0
HFD1_k127_6552062_7 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000001077 202.0
HFD1_k127_6552062_8 Periplasmic or secreted lipoprotein - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0032153,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000001759 144.0
HFD1_k127_6552062_9 stringent starvation protein b K03600 GO:0000502,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0009376,GO:0009893,GO:0009894,GO:0009896,GO:0010604,GO:0019222,GO:0019899,GO:0031597,GO:0032781,GO:0032991,GO:0042176,GO:0042802,GO:0042803,GO:0043085,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043462,GO:0044093,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045732,GO:0046983,GO:0048518,GO:0050789,GO:0050790,GO:0051117,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0097159,GO:1901363,GO:1902494,GO:1904949,GO:1905368,GO:1905369,GO:1990904 - 0.000000000000000000000000000000005865 135.0
HFD1_k127_6560631_0 COG2230 Cyclopropane fatty acid synthase and related methyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000001409 229.0
HFD1_k127_6560631_1 COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component K09014 GO:0003674,GO:0005488,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000001324 209.0
HFD1_k127_6560631_2 - - - - 0.0000000000000000000000000000000000000000000000000032 184.0
HFD1_k127_6563228_0 Limonene-1,2-epoxide hydrolase catalytic domain K10533 - 3.3.2.8 0.00000000000000000000000000001179 122.0
HFD1_k127_6563228_1 Alpha/beta hydrolase family - - - 0.000000006912 59.0
HFD1_k127_6569981_0 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008835 361.0
HFD1_k127_6569981_1 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 336.0
HFD1_k127_6569981_2 PFAM Tannase and feruloyl esterase - - - 0.000000000000000000000002068 104.0
HFD1_k127_657464_0 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 9.14e-204 649.0
HFD1_k127_657464_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 537.0
HFD1_k127_657464_2 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 354.0
HFD1_k127_657464_3 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005746 330.0
HFD1_k127_657464_4 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000148 267.0
HFD1_k127_657464_5 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides - - - 0.0000000000000000000000000000000000000000000000000000000001807 214.0
HFD1_k127_657464_6 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.0000000000000000000000000000000000000000000000000001691 193.0
HFD1_k127_6590764_0 DinB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001134 258.0
HFD1_k127_6590764_1 - - - - 0.000000000000000000000000000000002497 136.0
HFD1_k127_6590764_2 Bacterial protein of unknown function (DUF899) - - - 0.00000000001001 64.0
HFD1_k127_6591517_0 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 1.501e-318 979.0
HFD1_k127_6591517_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 362.0
HFD1_k127_6591517_2 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 357.0
HFD1_k127_6591517_3 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 328.0
HFD1_k127_6591517_4 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001109 273.0
HFD1_k127_6591517_5 helix_turn_helix, Lux Regulon K14987 - - 0.00000000000000000001103 102.0
HFD1_k127_6606834_0 poly(3-hydroxyalkanoate) depolymerase K22250 - 3.1.1.76 0.0000000000000000000000000000000000000000000000000000000000000000001467 237.0
HFD1_k127_6606834_1 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000000000000001657 232.0
HFD1_k127_6606834_2 - - - - 0.000000000000000000000000000007363 128.0
HFD1_k127_6646038_0 Proton-conducting membrane transporter - - - 1.519e-267 839.0
HFD1_k127_6646038_1 Proton-conducting membrane transporter - - - 1.436e-224 711.0
HFD1_k127_6646038_2 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 542.0
HFD1_k127_6646038_3 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 518.0
HFD1_k127_6646038_4 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 450.0
HFD1_k127_6646038_5 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 386.0
HFD1_k127_6646038_6 COG4237 Hydrogenase 4 membrane component (E) K12140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006479 307.0
HFD1_k127_6646038_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000001006 145.0
HFD1_k127_6646038_8 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000002133 119.0
HFD1_k127_6646038_9 Thrombospondin type 3 repeat - - - 0.00000004619 60.0
HFD1_k127_6653926_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 420.0
HFD1_k127_6653926_1 methyltransferase - - - 0.000000000000000000002762 96.0
HFD1_k127_6663481_0 Diguanylate cyclase - - - 2.529e-221 711.0
HFD1_k127_6663481_1 Cys/Met metabolism PLP-dependent enzyme K01739,K01740 - 2.5.1.48,2.5.1.49 0.0000000000000000001568 89.0
HFD1_k127_6663481_2 dNA-binding protein - - - 0.000003079 51.0
HFD1_k127_6668310_0 COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 545.0
HFD1_k127_6668310_1 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 364.0
HFD1_k127_6668310_2 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 340.0
HFD1_k127_6668310_3 haemagglutination activity domain - - - 0.0000000000000000000000000000001901 134.0
HFD1_k127_6674333_0 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 396.0
HFD1_k127_6674333_1 Peptidase_C39 like family - - - 0.0000000000000000000000000000000000000000000000000000000000001793 235.0
HFD1_k127_6674333_2 - - - - 0.00000000007303 63.0
HFD1_k127_6674902_0 NADH ubiquinone oxidoreductase subunit K00341 - 1.6.5.3 7.2e-238 750.0
HFD1_k127_6674902_1 NADH ubiquinone oxidoreductase subunit K00342 - 1.6.5.3 5.368e-216 682.0
HFD1_k127_6674902_2 Belongs to the complex I subunit 6 family K00339 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000003001 206.0
HFD1_k127_6674902_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000000000000759 166.0
HFD1_k127_6674902_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000438 144.0
HFD1_k127_6674902_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000003161 102.0
HFD1_k127_6686301_0 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 1.06e-228 717.0
HFD1_k127_6686301_1 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000003398 152.0
HFD1_k127_6691572_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 1.727e-220 707.0
HFD1_k127_6691572_1 Ferric uptake regulator family K03711 - - 0.00000000000000000000000000001964 118.0
HFD1_k127_6691572_2 PFAM Ferrous iron transporter, FeoA subunit K04758 - - 0.0000000000000000004981 90.0
HFD1_k127_6697299_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 1.872e-212 672.0
HFD1_k127_6697299_1 Retinal pigment epithelial membrane protein K21822 - 1.13.11.82 0.000000000000000000000000000000000000000000000000000000000002209 213.0
HFD1_k127_6697299_2 - - - - 0.000000000000000005611 88.0
HFD1_k127_6697299_3 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.00000000001629 64.0
HFD1_k127_6697299_4 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000006684 71.0
HFD1_k127_6701373_0 2-nitropropane dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957 501.0
HFD1_k127_6701373_1 Magnesium transport protein CorA K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002597 280.0
HFD1_k127_6701373_2 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000005191 165.0
HFD1_k127_6701373_3 Protein of unknown function (DUF502) - - - 0.00000000000000000000000004658 115.0
HFD1_k127_6701373_4 Signal transduction histidine kinase - - - 0.0000000000000000000004614 101.0
HFD1_k127_6754584_0 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 303.0
HFD1_k127_6754584_1 ATPase, AAA K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 307.0
HFD1_k127_6754584_2 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 303.0
HFD1_k127_6754584_3 Hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006939 295.0
HFD1_k127_6754584_4 COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein K03790 - 2.3.1.128 0.000000000000000000000000000000000001448 157.0
HFD1_k127_6754584_5 protein conserved in bacteria K09764 - - 0.0000000000000000000000006734 107.0
HFD1_k127_6754584_6 - - - - 0.000000000000001737 77.0
HFD1_k127_675541_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 474.0
HFD1_k127_675541_1 GMC oxidoreductase K00108 - 1.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004118 453.0
HFD1_k127_675541_2 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 366.0
HFD1_k127_675541_3 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007637 278.0
HFD1_k127_675541_5 Beta-lactamase - - - 0.0000000000000002048 79.0
HFD1_k127_6783738_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 1.486e-274 855.0
HFD1_k127_6783738_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 553.0
HFD1_k127_6783738_2 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000004655 173.0
HFD1_k127_6783738_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000003255 166.0
HFD1_k127_6783738_4 Ribosomal protein S21 K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000403 120.0
HFD1_k127_6786992_0 Belongs to the major facilitator superfamily K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 610.0
HFD1_k127_6797195_0 FMN-dependent dehydrogenase K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007879 368.0
HFD1_k127_6797195_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 340.0
HFD1_k127_6797195_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006511 293.0
HFD1_k127_6797195_3 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000008821 157.0
HFD1_k127_6799064_0 Biotin carboxylase - - - 0.0 1788.0
HFD1_k127_6799064_1 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000004748 127.0
HFD1_k127_6800193_0 Belongs to the PEP-utilizing enzyme family K08484 GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008965,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0016775,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564,GO:1901698 2.7.3.9 6.417e-291 911.0
HFD1_k127_6800193_1 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 437.0
HFD1_k127_6800193_2 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 355.0
HFD1_k127_6800193_3 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010468,GO:0010604,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0033554,GO:0034353,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0043487,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0045935,GO:0046483,GO:0046700,GO:0046872,GO:0048518,GO:0048519,GO:0048522,GO:0050779,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000001022 247.0
HFD1_k127_6800193_4 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000000000000000000000000000007799 214.0
HFD1_k127_6805873_0 COG1199 Rad3-related DNA helicases K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 609.0
HFD1_k127_6805873_1 Helix-turn-helix domain - - - 0.000000000000000000000000000000000137 137.0
HFD1_k127_6805873_2 HEAT repeats - - - 0.00000000000000000000000000006386 123.0
HFD1_k127_6805873_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000003878 89.0
HFD1_k127_6805873_4 Plasmid stability protein K21495 - - 0.000000002565 64.0
HFD1_k127_6805873_5 Belongs to the peptidase M16 family - - - 0.00005963 48.0
HFD1_k127_680894_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 1.77e-291 905.0
HFD1_k127_680894_1 - - - - 0.000000214 55.0
HFD1_k127_681958_0 peptidase dimerisation domain protein K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 464.0
HFD1_k127_681958_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005102 269.0
HFD1_k127_681958_10 - - - - 0.00000004108 66.0
HFD1_k127_681958_2 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000441 247.0
HFD1_k127_681958_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000008062 213.0
HFD1_k127_681958_4 Predicted membrane protein (DUF2306) - - - 0.0000000000000000000000000000000000000000000000000002942 193.0
HFD1_k127_681958_5 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000001191 173.0
HFD1_k127_681958_6 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000001675 145.0
HFD1_k127_681958_7 - - - - 0.0000000000000000000000000000000000002163 152.0
HFD1_k127_681958_8 - - - - 0.000000000000000000000004276 107.0
HFD1_k127_681958_9 - - - - 0.0000000000000000008461 91.0
HFD1_k127_6821169_0 PFAM metal-dependent phosphohydrolase, HD sub domain K01120 - 3.1.4.17 0.0000000000000000000001318 106.0
HFD1_k127_6821169_1 enzyme of heme biosynthesis - - - 0.000005196 57.0
HFD1_k127_6838362_0 Luciferase-like monooxygenase K14733 - 1.14.13.107 1.054e-195 616.0
HFD1_k127_6838362_1 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 594.0
HFD1_k127_6838362_2 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001851 271.0
HFD1_k127_6856713_0 3-methyladenine DNA glycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001447 260.0
HFD1_k127_6856713_1 Metallopeptidase family M24 K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000001589 249.0
HFD1_k127_6856713_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000000000000000000000000000000000000000000000000000000000000000000004673 239.0
HFD1_k127_6856713_3 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000004082 239.0
HFD1_k127_6856713_4 - - - - 0.0000000000000000000000387 104.0
HFD1_k127_6856893_0 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000001748 129.0
HFD1_k127_6856893_1 Major Facilitator - - - 0.0000000000000000000000001328 119.0
HFD1_k127_6856893_2 - - - - 0.000000000000000000000001108 106.0
HFD1_k127_6856893_3 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000001027 81.0
HFD1_k127_6856893_4 PFAM OmpA domain protein transmembrane region-containing protein - - - 0.00000001085 64.0
HFD1_k127_6863179_0 Belongs to the glutamate synthase family - - - 5.76e-205 656.0
HFD1_k127_6863179_1 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 328.0
HFD1_k127_6863179_2 COG0210 Superfamily I DNA and RNA helicases K03657 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006289,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0022607,GO:0031297,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0042802,GO:0043142,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045005,GO:0046483,GO:0050896,GO:0051259,GO:0051260,GO:0051276,GO:0051716,GO:0065003,GO:0070035,GO:0070581,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 286.0
HFD1_k127_6863179_3 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008412,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.5.1.39 0.000000000000000000000000000000000001255 141.0
HFD1_k127_6873335_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0 1662.0
HFD1_k127_6873974_0 sulfuric ester hydrolase activity K07014 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 409.0
HFD1_k127_6877803_0 Converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 558.0
HFD1_k127_6877803_1 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 365.0
HFD1_k127_6877803_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000366 252.0
HFD1_k127_6877803_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001721 246.0
HFD1_k127_6877803_4 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000003922 215.0
HFD1_k127_6877803_5 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000009475 176.0
HFD1_k127_6877803_6 COG0500 SAM-dependent methyltransferases - - - 0.000000000000001974 90.0
HFD1_k127_6877803_7 WW domain-containing oxidoreductase K19329 GO:0000122,GO:0001501,GO:0001503,GO:0001649,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005667,GO:0005737,GO:0005739,GO:0005794,GO:0005829,GO:0006355,GO:0006357,GO:0006629,GO:0006873,GO:0006874,GO:0006875,GO:0006915,GO:0006950,GO:0006952,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0008150,GO:0008152,GO:0008202,GO:0008219,GO:0009314,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009653,GO:0009719,GO:0009887,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010212,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010646,GO:0010647,GO:0010648,GO:0010941,GO:0010942,GO:0012501,GO:0012505,GO:0016491,GO:0019219,GO:0019222,GO:0019725,GO:0019899,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030003,GO:0030111,GO:0030154,GO:0030178,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032501,GO:0032502,GO:0032991,GO:0035556,GO:0042221,GO:0042592,GO:0042742,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044798,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0046983,GO:0048037,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048705,GO:0048731,GO:0048856,GO:0048869,GO:0048878,GO:0050662,GO:0050789,GO:0050794,GO:0050801,GO:0050829,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0051707,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055114,GO:0060255,GO:0065007,GO:0065008,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071495,GO:0071559,GO:0071560,GO:0071704,GO:0072331,GO:0072332,GO:0072503,GO:0072507,GO:0080090,GO:0090575,GO:0097190,GO:0097191,GO:0097193,GO:0098542,GO:0098771,GO:1901360,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2000377,GO:2001141,GO:2001233,GO:2001235,GO:2001236,GO:2001238,GO:2001239,GO:2001241 - 0.0000000002612 64.0
HFD1_k127_6878245_0 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 555.0
HFD1_k127_6894439_0 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007352 591.0
HFD1_k127_6894439_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 483.0
HFD1_k127_6894439_2 Conserved Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 309.0
HFD1_k127_6894439_3 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000003244 230.0
HFD1_k127_6906047_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 557.0
HFD1_k127_6906047_1 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 336.0
HFD1_k127_6906047_2 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006476 273.0
HFD1_k127_6906047_3 Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins K13643 - - 0.00000000000000000000000000000000000000000000000000000004862 202.0
HFD1_k127_6906047_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000005501 189.0
HFD1_k127_6906678_0 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 346.0
HFD1_k127_6906678_1 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000001917 231.0
HFD1_k127_6906678_2 Domain of unknown function (DUF4381) - - - 0.0000000000000000000002096 106.0
HFD1_k127_6906678_3 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000002139 86.0
HFD1_k127_6927251_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 342.0
HFD1_k127_6927251_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 325.0
HFD1_k127_6927251_2 AcrB/AcrD/AcrF family K07787 - - 0.00000000000000000000000008406 108.0
HFD1_k127_6931134_0 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 325.0
HFD1_k127_6931134_1 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000002362 226.0
HFD1_k127_694519_0 inner membrane component K02050,K15599 - - 0.00000000000000000000000000000000000000000000000000000000004267 218.0
HFD1_k127_694519_1 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000001483 121.0
HFD1_k127_6946915_0 Pyridoxal phosphate biosynthetic protein PdxA K00097 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050570,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 366.0
HFD1_k127_6946915_1 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 338.0
HFD1_k127_6946915_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000002505 237.0
HFD1_k127_6946915_3 ApaG domain K06195 - - 0.00000000000000000000000000000000000000004475 154.0
HFD1_k127_6947979_0 Protein of unknown function (DUF1343) - - - 1.449e-210 660.0
HFD1_k127_6947979_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576,K01652 - 2.2.1.6,4.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 553.0
HFD1_k127_6947979_2 Macro domain - - - 0.000000000000000000000000000000000000000000000000000000000000001067 224.0
HFD1_k127_6947979_3 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000034 229.0
HFD1_k127_6947979_4 Domain of unknown function (DUF4136) - - - 0.000000000000000000000002744 111.0
HFD1_k127_6949934_0 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 9.456e-205 676.0
HFD1_k127_6949934_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 320.0
HFD1_k127_6949934_2 Response regulator of the LytR AlgR family K02477,K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 296.0
HFD1_k127_6949934_3 signal transduction protein with a C-terminal ATPase domain K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 299.0
HFD1_k127_6966194_0 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 332.0
HFD1_k127_6966194_1 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 306.0
HFD1_k127_6966194_2 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000002362 226.0
HFD1_k127_6966194_3 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.0000000000000000000000000000000000000000000000002796 183.0
HFD1_k127_6980189_0 acyl-CoA thioesterase K10805 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003504 263.0
HFD1_k127_6980189_1 Belongs to the GST superfamily K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000003174 171.0
HFD1_k127_6980189_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000001503 149.0
HFD1_k127_6980189_3 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000001557 124.0
HFD1_k127_6989399_0 Aldehyde oxidase and xanthine dehydrogenase K03520 - 1.2.5.3 4.106e-278 863.0
HFD1_k127_6989399_1 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 315.0
HFD1_k127_6989399_2 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000004467 229.0
HFD1_k127_6989574_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 507.0
HFD1_k127_6989574_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 405.0
HFD1_k127_6989574_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 369.0
HFD1_k127_6989574_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 306.0
HFD1_k127_6989574_4 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002185 241.0
HFD1_k127_7012900_0 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 355.0
HFD1_k127_7012900_1 Winged helix DNA-binding domain K09927 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006671 264.0
HFD1_k127_7012900_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000006369 256.0
HFD1_k127_7012900_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 0.000000000000008361 74.0
HFD1_k127_7021575_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000845 505.0
HFD1_k127_7021575_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 283.0
HFD1_k127_7021575_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772,K03783,K03815,K19696 GO:0003674,GO:0003824,GO:0004731,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006148,GO:0006149,GO:0006152,GO:0006161,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008477,GO:0008617,GO:0009056,GO:0009116,GO:0009119,GO:0009120,GO:0009164,GO:0009987,GO:0015949,GO:0016043,GO:0016740,GO:0016757,GO:0016763,GO:0016787,GO:0016798,GO:0016799,GO:0019439,GO:0022607,GO:0034214,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042453,GO:0042454,GO:0042802,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046094,GO:0046102,GO:0046115,GO:0046121,GO:0046122,GO:0046124,GO:0046128,GO:0046130,GO:0046483,GO:0046700,GO:0047724,GO:0047975,GO:0051259,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072521,GO:0072523,GO:1901068,GO:1901069,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658,GO:1903227,GO:1903228 2.4.2.1,2.4.2.28,2.4.2.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000907 260.0
HFD1_k127_7021575_3 phosphoribosyltransferase K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000001395 185.0
HFD1_k127_7021575_4 Peptidoglycan-binding protein, CsiV - - - 0.00000000000000001589 95.0
HFD1_k127_7040121_0 Glycosyltransferase like family 2 K16555 - - 0.000000000000000000000000000000000000000003202 168.0
HFD1_k127_7040121_1 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000004544 134.0
HFD1_k127_7040121_2 - - - - 0.00003213 56.0
HFD1_k127_7040878_0 Serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 376.0
HFD1_k127_7040878_1 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 329.0
HFD1_k127_7040878_2 Crp Fnr family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000603 270.0
HFD1_k127_7040878_3 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000006991 209.0
HFD1_k127_7040878_4 Pyridoxamine 5'-phosphate oxidase like - - - 0.000000000000000000000000000000000000000000000000000002083 198.0
HFD1_k127_7041989_0 Signal transducing histidine kinase, homodimeric domain K02487,K06596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 484.0
HFD1_k127_7053388_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 471.0
HFD1_k127_7061857_0 Histidine kinase K10916 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000005643 270.0
HFD1_k127_7061857_1 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000489 226.0
HFD1_k127_7061857_2 ABC-type glycine betaine transport system K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000001144 192.0
HFD1_k127_7062695_0 Transposase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 496.0
HFD1_k127_7062695_1 sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 313.0
HFD1_k127_7062695_2 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 2.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000007898 275.0
HFD1_k127_7062695_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000584 196.0
HFD1_k127_7062695_4 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0000000000000000000000002328 107.0
HFD1_k127_707128_0 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1620.0
HFD1_k127_707128_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 487.0
HFD1_k127_707128_2 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 417.0
HFD1_k127_707128_3 Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins K07400 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0010467,GO:0015976,GO:0016043,GO:0016226,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002064 275.0
HFD1_k127_7082705_0 COG0191 Fructose tagatose bisphosphate aldolase K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 568.0
HFD1_k127_7082705_1 COG2267 Lysophospholipase K01048 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001315 289.0
HFD1_k127_7082705_2 Belongs to the phosphoglycerate kinase family K00927 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000002378 237.0
HFD1_k127_7082705_3 Protein of unknown function (DUF3313) - - - 0.000001146 58.0
HFD1_k127_7085749_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 542.0
HFD1_k127_7085749_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000001224 171.0
HFD1_k127_7085749_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000103 151.0
HFD1_k127_7085749_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000001035 140.0
HFD1_k127_7092991_0 PFAM Tannase and feruloyl esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 523.0
HFD1_k127_7094733_0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 3.525e-209 662.0
HFD1_k127_7094733_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000838 145.0
HFD1_k127_7105976_0 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 443.0
HFD1_k127_7105976_1 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 344.0
HFD1_k127_7105976_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 340.0
HFD1_k127_7105976_3 - - - - 0.0001461 47.0
HFD1_k127_7115635_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000007786 244.0
HFD1_k127_7115635_1 ADP-ribose pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000005372 230.0
HFD1_k127_7115635_2 nUDIX hydrolase K01515,K03574 - 3.6.1.13,3.6.1.55 0.000000000000000000000000000000000000000008712 162.0
HFD1_k127_7130594_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 614.0
HFD1_k127_7130594_1 Aminoglycoside phosphotransferase - - - 0.000000000000000000003885 104.0
HFD1_k127_7137494_0 PQQ-like domain K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 439.0
HFD1_k127_7137494_1 Glyoxalase-like domain - - - 0.000000000000000000002256 102.0
HFD1_k127_7137494_2 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000001555 59.0
HFD1_k127_7138761_0 His Kinase A (phosphoacceptor) domain - - - 4.437e-259 810.0
HFD1_k127_7138761_1 Oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 530.0
HFD1_k127_7138761_2 cheY-homologous receiver domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 398.0
HFD1_k127_7138761_3 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000006317 227.0
HFD1_k127_7138761_4 Protein of unknown function (DUF3307) - - - 0.000000000000000000001665 98.0
HFD1_k127_7138761_5 SMART HTH transcriptional regulator, Crp - - - 0.00000000001471 65.0
HFD1_k127_7144341_0 phosphate-selective porin O and P - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008685 437.0
HFD1_k127_7144341_1 Periplasmic solute binding protein K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 355.0
HFD1_k127_7144341_2 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000126 282.0
HFD1_k127_7164820_0 Secreted protein, containing von Willebrand factor (VWF) type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 349.0
HFD1_k127_7164820_1 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 332.0
HFD1_k127_7164820_2 - - - - 0.000000000000000000000000000000000000000000000000000005015 207.0
HFD1_k127_7164820_3 - - - - 0.0000000000000000000000000000000003076 139.0
HFD1_k127_7164820_4 Secreted protein, containing von Willebrand factor - - - 0.00000138 61.0
HFD1_k127_7164820_5 - - - - 0.0001792 48.0
HFD1_k127_7186519_0 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 518.0
HFD1_k127_7186519_1 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 358.0
HFD1_k127_7186519_2 Belongs to the glycosyl hydrolase 28 family - - - 0.0000000000000000000000000000000000000000006044 165.0
HFD1_k127_7201943_0 PFAM Carbon starvation protein CstA K06200 - - 0.0 1044.0
HFD1_k127_7201943_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008255 282.0
HFD1_k127_7201943_2 acetyltransferase - - - 0.000000000000000000000000000000000000003053 151.0
HFD1_k127_7201943_3 Selenoprotein, putative - - - 0.00000000004282 72.0
HFD1_k127_7230356_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 611.0
HFD1_k127_7230356_1 Aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 517.0
HFD1_k127_7230356_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 404.0
HFD1_k127_7230356_3 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 389.0
HFD1_k127_7230356_4 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 346.0
HFD1_k127_7230356_5 overlaps another CDS with the same product name K21019 - 2.7.7.65 0.000000000000000000000000000000000000000000000184 182.0
HFD1_k127_7242580_0 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006987 479.0
HFD1_k127_7242580_1 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00167 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 460.0
HFD1_k127_7255572_0 alcohol dehydrogenase (NAD) activity K00001,K00121,K02267,K13980,K18857 GO:0000302,GO:0001101,GO:0001666,GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006970,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009410,GO:0009413,GO:0009414,GO:0009415,GO:0009628,GO:0009636,GO:0009651,GO:0009719,GO:0009725,GO:0009737,GO:0009743,GO:0009744,GO:0010033,GO:0010035,GO:0010038,GO:0010243,GO:0014070,GO:0014074,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0031000,GO:0032355,GO:0033993,GO:0034285,GO:0036270,GO:0036293,GO:0042221,GO:0042493,GO:0042542,GO:0042802,GO:0042803,GO:0043279,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046686,GO:0046983,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0055114,GO:0065007,GO:0070482,GO:0071944,GO:0080134,GO:0080135,GO:0097305,GO:1900037,GO:1900039,GO:1901698,GO:1901700 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 524.0
HFD1_k127_7255572_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 437.0
HFD1_k127_7255572_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 429.0
HFD1_k127_7255572_3 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 322.0
HFD1_k127_7255572_4 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000005463 269.0
HFD1_k127_726195_0 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 561.0
HFD1_k127_726195_1 Belongs to the TPP enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 469.0
HFD1_k127_726195_2 arylamine N-acetyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007839 266.0
HFD1_k127_726195_3 Peptidase M50 - - - 0.0000000000000000000000000000000000000001488 160.0
HFD1_k127_7266209_0 Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 493.0
HFD1_k127_7266209_1 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008073 447.0
HFD1_k127_7266209_2 Belongs to the UPF0307 family K09889 - - 0.00000000000000000000000000002523 126.0
HFD1_k127_7266209_3 COG1925 Phosphotransferase system, HPr-related proteins K08485,K11189 GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006808,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071704,GO:1901564,GO:1901698 - 0.00000000000000000000000001302 111.0
HFD1_k127_7266209_4 P-loop ATPase protein family K06958 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000002665 64.0
HFD1_k127_726914_0 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 392.0
HFD1_k127_726914_1 Flavin-binding monooxygenase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 386.0
HFD1_k127_726914_2 Protein of unknown function (DUF2855) - - - 0.0000000000000000000000000000008752 124.0
HFD1_k127_7276494_0 metal-dependent hydrolase of the TIM-barrel fold K07046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 454.0
HFD1_k127_7276494_1 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000007655 153.0
HFD1_k127_7277995_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2224.0
HFD1_k127_7277995_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 3.808e-199 624.0
HFD1_k127_7277995_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 348.0
HFD1_k127_7277995_3 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 299.0
HFD1_k127_7277995_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000011 238.0
HFD1_k127_7277995_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000000008105 235.0
HFD1_k127_7277995_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0046983,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000008179 175.0
HFD1_k127_7277995_7 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000000000000000000000000000000001725 147.0
HFD1_k127_7299670_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 557.0
HFD1_k127_7299670_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007549 578.0
HFD1_k127_7299670_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009898,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0019843,GO:0019897,GO:0019898,GO:0022613,GO:0031234,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0036211,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044877,GO:0046777,GO:0070181,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 342.0
HFD1_k127_7299670_3 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 334.0
HFD1_k127_7299670_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 297.0
HFD1_k127_7299670_5 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000001088 225.0
HFD1_k127_7299670_6 Involved in DNA repair and RecF pathway recombination K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 - 0.00000000000000000000000000000000000000000000003007 179.0
HFD1_k127_7299670_7 Domain of unknown function (DUF4845) - - - 0.00000000000000002898 90.0
HFD1_k127_7321027_0 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 387.0
HFD1_k127_7321027_1 Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000169 152.0
HFD1_k127_7321027_2 Forkhead associated domain - - - 0.000000000000000000000004767 115.0
HFD1_k127_7321027_3 histidine kinase HAMP region domain protein K07641 - 2.7.13.3 0.000000000001563 70.0
HFD1_k127_7321027_4 Protein tyrosine kinase K11912,K12132 - 2.7.11.1 0.000001277 58.0
HFD1_k127_7322923_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 497.0
HFD1_k127_7322923_1 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002128 291.0
HFD1_k127_7322923_2 - - - - 0.000000000000000000000000000000000000000000000008803 176.0
HFD1_k127_7322923_3 TIGRFAM conserved - - - 0.0000000000000000000000000000000000000000004323 162.0
HFD1_k127_7324046_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 415.0
HFD1_k127_7324046_1 protein conserved in bacteria K09938 - - 0.0000000000000000000000000000000000000005386 165.0
HFD1_k127_7324046_2 CDP-alcohol phosphatidyltransferase - - - 0.00000000000000000000000000000000000002591 153.0
HFD1_k127_7324046_3 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA K10763 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113 - 0.000000000000000002371 96.0
HFD1_k127_7324714_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 419.0
HFD1_k127_7324714_1 COG4796 Type II secretory pathway, component HofQ K02507,K02666 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 411.0
HFD1_k127_7324714_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000000000000000000000000002472 187.0
HFD1_k127_7324714_3 Type II secretory pathway component ExeA K02450,K12283 - - 0.00000000001501 71.0
HFD1_k127_7346060_0 Major Facilitator Superfamily K03446 - - 1.651e-245 775.0
HFD1_k127_7346060_1 Biotin-lipoyl like K03543,K15549 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 426.0
HFD1_k127_7346060_2 flavoprotein involved in K transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 365.0
HFD1_k127_7346060_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000003681 220.0
HFD1_k127_7346060_4 transcriptional regulator - GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009987,GO:0010212,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000006077 201.0
HFD1_k127_7357365_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 422.0
HFD1_k127_7357365_1 Pseudouridylate K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 372.0
HFD1_k127_7357365_2 transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000109 246.0
HFD1_k127_7357365_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000004742 168.0
HFD1_k127_7357365_4 Major facilitator K08218 - - 0.0000000003305 68.0
HFD1_k127_7388153_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.021e-245 768.0
HFD1_k127_7388153_1 Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 614.0
HFD1_k127_7388153_10 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006549 269.0
HFD1_k127_7388153_11 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002271 234.0
HFD1_k127_7388153_12 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000001025 174.0
HFD1_k127_7388153_13 Putative FMN-binding domain K07734 - - 0.00000000000000000000000000000000000000000007461 173.0
HFD1_k127_7388153_14 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000001629 136.0
HFD1_k127_7388153_15 Sucrose-6F-phosphate phosphohydrolase - - - 0.000000000003848 73.0
HFD1_k127_7388153_16 COG0668 Small-conductance mechanosensitive channel - - - 0.00000000003361 72.0
HFD1_k127_7388153_2 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 394.0
HFD1_k127_7388153_3 Multidrug efflux pump K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 357.0
HFD1_k127_7388153_4 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 332.0
HFD1_k127_7388153_5 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 311.0
HFD1_k127_7388153_6 KR domain K00059,K07535 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 304.0
HFD1_k127_7388153_7 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 306.0
HFD1_k127_7388153_8 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002057 251.0
HFD1_k127_7388153_9 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003885 271.0
HFD1_k127_7398429_0 ABC transporter transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006828 509.0
HFD1_k127_7398429_1 Methyl-transferase - - - 0.0000000000000000000000000000000000000000000000003807 184.0
HFD1_k127_7398429_2 PFAM Alcohol dehydrogenase zinc-binding domain protein K07119 - - 0.00000000000000000000000000000000002565 137.0
HFD1_k127_7400816_0 COG2706 3-carboxymuconate cyclase K07404 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000006536 202.0
HFD1_k127_7400816_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K03366 - 1.1.1.304,1.1.1.76 0.00000000000000000000000000000000000000000000000001737 201.0
HFD1_k127_7400816_2 NADPH quinone reductase - - - 0.00000000000000000000000000000000000000001069 160.0
HFD1_k127_7400816_3 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.00000000000000000000001531 107.0
HFD1_k127_7400816_4 Belongs to the FGGY kinase family K00851 - 2.7.1.12 0.0000000000000000001307 104.0
HFD1_k127_7400816_5 Aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000001009 89.0
HFD1_k127_7402642_0 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000005249 252.0
HFD1_k127_7402642_1 Sugar (and other) transporter K08369 - - 0.000000000000000000000000000000000000000000955 177.0
HFD1_k127_7402642_2 AntiSigma factor - - - 0.000000000000000000000000000003437 127.0
HFD1_k127_7402642_3 - - - - 0.0005553 49.0
HFD1_k127_7407357_0 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 344.0
HFD1_k127_7407357_1 Glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000000000000000000003845 152.0
HFD1_k127_7407357_2 FR47-like protein - - - 0.0000000000000000000000000000000000001517 153.0
HFD1_k127_7409546_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 455.0
HFD1_k127_7409546_1 Major facilitator superfamily K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 409.0
HFD1_k127_7409546_2 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 362.0
HFD1_k127_7409546_3 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002295 285.0
HFD1_k127_7409546_4 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000001451 172.0
HFD1_k127_7409546_5 Cytochrome c - - - 0.00000000000000000000000000000004753 132.0
HFD1_k127_7409546_6 Domain of unknown function (DUF4345) - - - 0.000000001002 67.0
HFD1_k127_7431949_0 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 580.0
HFD1_k127_7431949_1 PFAM aminoglycoside phosphotransferase K04343 - 2.7.1.72 0.000000000000000000000000000000000000000000000000000000112 209.0
HFD1_k127_7431949_2 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.000000000000000000000000000002244 122.0
HFD1_k127_7444353_0 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001608 263.0
HFD1_k127_7444353_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 0.00000000000000000000000000000000000000007924 160.0
HFD1_k127_7446095_0 Hydroxymethylglutaryl-coenzyme A reductase K00054 - 1.1.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 494.0
HFD1_k127_7446095_1 Hydroxymethylglutaryl-coenzyme A synthase N terminal K01641,K15311 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008081 394.0
HFD1_k127_7446095_2 NUDIX domain K01823 GO:0003674,GO:0003824,GO:0004452,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0019637,GO:0033554,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046490,GO:0050896,GO:0051716,GO:0071704,GO:0090407,GO:1901576 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000006379 242.0
HFD1_k127_7455691_0 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 436.0
HFD1_k127_7455691_1 MBOAT, membrane-bound O-acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008961 413.0
HFD1_k127_7456471_0 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000004009 251.0
HFD1_k127_7456471_1 Alkanesulfonate monooxygenase K04091 - 1.14.14.5 0.000000000000000000000000000000000000000000000000000000002691 205.0
HFD1_k127_7456471_2 FAD dependent oxidoreductase K13796 - - 0.00000000000000000000000000000009481 126.0
HFD1_k127_7468117_0 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007718 477.0
HFD1_k127_7468117_1 fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 289.0
HFD1_k127_7473882_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 594.0
HFD1_k127_7473882_1 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 563.0
HFD1_k127_7473882_2 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 351.0
HFD1_k127_7473882_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001517 258.0
HFD1_k127_7487541_0 Belongs to the ClpA ClpB family K03694 - - 0.0 1125.0
HFD1_k127_7487541_1 Converts isocitrate to alpha ketoglutarate K00031 - 1.1.1.42 6.343e-219 685.0
HFD1_k127_7487541_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 492.0
HFD1_k127_7487541_3 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009112 291.0
HFD1_k127_7487541_4 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007646 274.0
HFD1_k127_7487541_5 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.0000000000000000000000000000000000000000000004861 171.0
HFD1_k127_7487541_6 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 - 0.0000000000000000000000000000000000000007015 151.0
HFD1_k127_7487541_7 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000152 139.0
HFD1_k127_7487541_8 Cold shock K03704 - - 0.00000000000000000000000000002373 121.0
HFD1_k127_7487541_9 Aminopeptidase - - - 0.0000000009091 61.0
HFD1_k127_749172_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 557.0
HFD1_k127_749172_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family K00569 - 2.1.1.67 0.000000000000000000000000000000000000000000000000000000000001449 226.0
HFD1_k127_749172_2 Winged helix DNA-binding domain K09927 - - 0.00000000000000000000000000000000000000000000007776 172.0
HFD1_k127_7502786_0 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 3.762e-291 922.0
HFD1_k127_7502786_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 396.0
HFD1_k127_7502786_2 SH3 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000009135 241.0
HFD1_k127_7502786_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000003334 211.0
HFD1_k127_7502786_4 Domain of unknown function (DUF4266) - - - 0.00000000000000000000001278 101.0
HFD1_k127_7514738_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 463.0
HFD1_k127_7514738_1 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008619 370.0
HFD1_k127_7514738_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000005591 129.0
HFD1_k127_7515972_0 Protein conserved in bacteria K09992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 317.0
HFD1_k127_7515972_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 309.0
HFD1_k127_7515972_2 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 291.0
HFD1_k127_753201_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 298.0
HFD1_k127_753201_1 Metal-dependent hydrolase K07044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003215 260.0
HFD1_k127_753201_2 TIM-barrel fold metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000002396 240.0
HFD1_k127_753201_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000007493 217.0
HFD1_k127_753201_4 Short-chain dehydrogenase reductase sdr K00038 - 1.1.1.53 0.00000000000000000000000000000000000000000000000000000001141 202.0
HFD1_k127_753201_5 D-isomer specific 2-hydroxyacid dehydrogenase K12972 - 1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000000003536 196.0
HFD1_k127_753201_6 2-oxopent-4-enoate hydratase activity K02554 - 4.2.1.80 0.00000000000000000000000000000000000000000000000002678 190.0
HFD1_k127_7532678_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 565.0
HFD1_k127_7532678_1 peptidase M20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009386 575.0
HFD1_k127_7532678_2 Cytosol aminopeptidase family, catalytic domain K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 495.0
HFD1_k127_7532678_3 TonB dependent receptor K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 392.0
HFD1_k127_7532678_4 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008828 302.0
HFD1_k127_7532678_5 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 289.0
HFD1_k127_7532678_6 endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003705 254.0
HFD1_k127_7532678_7 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000000000000000000000003086 194.0
HFD1_k127_7532678_8 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000001071 151.0
HFD1_k127_7546144_0 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007469 424.0
HFD1_k127_7546144_1 COG0657 Esterase lipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 323.0
HFD1_k127_7546144_2 metal-dependent hydrolase of the TIM-barrel fold K07046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 316.0
HFD1_k127_7589097_0 Domain of unknown function (DUF4214) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 312.0
HFD1_k127_7589097_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000004311 211.0
HFD1_k127_7592883_0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004017,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006412,GO:0006518,GO:0006629,GO:0006644,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0010467,GO:0015949,GO:0015950,GO:0015951,GO:0016070,GO:0016208,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019205,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 309.0
HFD1_k127_7592883_1 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006145 273.0
HFD1_k127_7597349_0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001801 277.0
HFD1_k127_7597349_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010608,GO:0015935,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031329,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904 - 0.000000000000000000000000000000000000000000000000000002234 193.0
HFD1_k127_7597349_2 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000002069 147.0
HFD1_k127_7597349_3 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000003022 151.0
HFD1_k127_7597349_4 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000003614 113.0
HFD1_k127_7597349_5 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000004777 85.0
HFD1_k127_7599906_0 Glycosyl transferase family 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 353.0
HFD1_k127_7599906_1 nucleoside-diphosphate sugar epimerases - - - 0.000000000000000000000000000000000000000000000000000000000000000008266 234.0
HFD1_k127_7599906_2 PFAM NAD-dependent epimerase dehydratase K00091,K01784 - 1.1.1.219,5.1.3.2 0.000000000000000000000000000000000000000000000000000001088 211.0
HFD1_k127_7599906_3 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase K13007 - - 0.000000000000000000000000000000000000000000000003241 192.0
HFD1_k127_7599906_4 Competence protein ComEA K02237 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.000000000000000001993 90.0
HFD1_k127_7599906_5 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008653,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1903509 - 0.0000000000006915 71.0
HFD1_k127_7600961_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 586.0
HFD1_k127_7600961_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 434.0
HFD1_k127_7600961_2 High frequency lysogenization protein HflD homolog K07153 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009898,GO:0016020,GO:0019897,GO:0019898,GO:0031234,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0071944,GO:0098552,GO:0098562 - 0.00000000000000000000000000000000003118 149.0
HFD1_k127_7605164_0 cytochrome P-450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009849 426.0
HFD1_k127_7605164_1 COG2211 Na melibiose symporter and related transporters - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 417.0
HFD1_k127_7605164_10 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001239 253.0
HFD1_k127_7605164_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003485 231.0
HFD1_k127_7605164_12 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000001102 170.0
HFD1_k127_7605164_13 retrograde transport, endosome to Golgi K07095 - - 0.000000000000000000000000000001709 128.0
HFD1_k127_7605164_14 sequence-specific DNA binding K15773 - - 0.00000000000000000000265 97.0
HFD1_k127_7605164_15 - - - - 0.000000000000000001888 91.0
HFD1_k127_7605164_16 - - - - 0.00000001981 64.0
HFD1_k127_7605164_2 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009848 362.0
HFD1_k127_7605164_3 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 358.0
HFD1_k127_7605164_4 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 346.0
HFD1_k127_7605164_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 343.0
HFD1_k127_7605164_6 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 333.0
HFD1_k127_7605164_7 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 322.0
HFD1_k127_7605164_8 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 327.0
HFD1_k127_7605164_9 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008889 324.0
HFD1_k127_7625242_0 Flavin-binding monooxygenase-like - - - 1.301e-263 828.0
HFD1_k127_7625242_1 Flavoprotein involved in K transport K03379 - 1.14.13.22 4.282e-208 660.0
HFD1_k127_7625242_2 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 332.0
HFD1_k127_7625242_3 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.000000000000000000000000000000003533 134.0
HFD1_k127_7625242_4 Crp-like helix-turn-helix domain - - - 0.000000000000000000000000000005829 121.0
HFD1_k127_7629425_0 COG1305 Transglutaminase-like enzymes K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000834 492.0
HFD1_k127_7629425_1 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000002979 223.0
HFD1_k127_7636506_0 Required for the activity of the bacterial periplasmic transport system of putrescine K11073 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 334.0
HFD1_k127_7636506_1 stress protein (general stress protein 26) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003078 250.0
HFD1_k127_7636506_2 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000154 239.0
HFD1_k127_7636506_3 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000005616 134.0
HFD1_k127_7636506_4 alpha/beta hydrolase fold - - - 0.0000000000000000006842 92.0
HFD1_k127_7637245_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009987,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 4.831e-250 784.0
HFD1_k127_7637245_1 DNA helicase K03657 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006289,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0022607,GO:0031297,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0042802,GO:0043142,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045005,GO:0046483,GO:0050896,GO:0051259,GO:0051260,GO:0051276,GO:0051716,GO:0065003,GO:0070035,GO:0070581,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 494.0
HFD1_k127_7649568_0 Flavoprotein involved in K transport K03379 - 1.14.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 477.0
HFD1_k127_7649568_1 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000729 277.0
HFD1_k127_7649568_2 Tetratricopeptide repeat - - - 0.0000008716 61.0
HFD1_k127_7652724_0 phosphomannomutase K15778 GO:0003674,GO:0003824,GO:0004615,GO:0005975,GO:0008150,GO:0008152,GO:0016853,GO:0016866,GO:0016868,GO:0044238,GO:0071704 5.4.2.2,5.4.2.8 8.189e-213 690.0
HFD1_k127_7652724_1 Catalyzes the ATP-dependent phosphorylation of N-acetyl- L-glutamate K00930,K22478 GO:0003674,GO:0003824,GO:0003991,GO:0004042,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016407,GO:0016410,GO:0016597,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0033554,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009816 420.0
HFD1_k127_7652724_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 GO:0000166,GO:0003674,GO:0003824,GO:0004632,GO:0004633,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0015936,GO:0015937,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032553,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 289.0
HFD1_k127_7652724_3 Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions K05501 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0007049,GO:0007346,GO:0008150,GO:0009295,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010948,GO:0010974,GO:0016043,GO:0019219,GO:0019222,GO:0022402,GO:0022607,GO:0031323,GO:0031326,GO:0031333,GO:0032271,GO:0032272,GO:0032465,GO:0032466,GO:0032506,GO:0032954,GO:0032955,GO:0042802,GO:0043085,GO:0043087,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043547,GO:0043565,GO:0043590,GO:0044085,GO:0044087,GO:0044093,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045786,GO:0045930,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051252,GO:0051301,GO:0051302,GO:0051336,GO:0051345,GO:0051726,GO:0051782,GO:0060255,GO:0061640,GO:0065007,GO:0065009,GO:0071840,GO:0080090,GO:0090529,GO:0097159,GO:0140110,GO:1901363,GO:1901891,GO:1901892,GO:1902410,GO:1902412,GO:1902413,GO:1903047,GO:1903436,GO:1903437,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000003372 234.0
HFD1_k127_7652724_4 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 GO:0000287,GO:0003674,GO:0003824,GO:0004588,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000003147 209.0
HFD1_k127_7652724_5 Domain of unknown function (DUF4124) - - - 0.00000000000000000000002393 108.0
HFD1_k127_766474_0 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 419.0
HFD1_k127_766474_1 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000000000000000001603 139.0
HFD1_k127_766474_2 acyl-CoA dehydrogenase - - - 0.000000000000000000000000002603 118.0
HFD1_k127_766474_3 Domain of Unknown Function (DUF349) - - - 0.000000001926 69.0
HFD1_k127_7682513_0 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 6.259e-195 611.0
HFD1_k127_7682513_1 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 397.0
HFD1_k127_7682513_2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000006508 263.0
HFD1_k127_7682513_3 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000008149 154.0
HFD1_k127_7682513_4 YjbR - - - 0.00000000000000000000000000000002173 136.0
HFD1_k127_7682513_5 YjbR - - - 0.000000000000001853 86.0
HFD1_k127_7682513_6 - - - - 0.0000000000008283 71.0
HFD1_k127_7702638_0 Magnesium transport protein CorA - - - 1.132e-225 711.0
HFD1_k127_7702638_1 Phospholipase D. Active site motifs. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 416.0
HFD1_k127_7702638_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006586 396.0
HFD1_k127_7702638_3 membrane protein, TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 306.0
HFD1_k127_7702638_4 - - - - 0.0000000000000000000000000000000000000000000000000000000006002 214.0
HFD1_k127_7702638_5 PFAM regulatory protein, ArsR - - - 0.000000000000000000000000000002652 124.0
HFD1_k127_7702638_6 Activator of Hsp90 ATPase 1 family protein - - - 0.0000000000000000000007121 98.0
HFD1_k127_7710271_0 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 474.0
HFD1_k127_7710271_1 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000000000001949 204.0
HFD1_k127_7710271_2 S1/P1 Nuclease - - - 0.0000000000000000000000000000000000000000000000000002454 198.0
HFD1_k127_7710271_3 - - - - 0.000000000000000223 86.0
HFD1_k127_7711718_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 1.169e-272 851.0
HFD1_k127_7711718_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 2.211e-269 835.0
HFD1_k127_7711718_10 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000002498 174.0
HFD1_k127_7711718_11 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000002166 152.0
HFD1_k127_7711718_12 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000001161 143.0
HFD1_k127_7711718_13 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000009311 117.0
HFD1_k127_7711718_2 Mannitol dehydrogenase rossman K00007 - 1.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 566.0
HFD1_k127_7711718_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 403.0
HFD1_k127_7711718_4 ATP synthase A chain K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 372.0
HFD1_k127_7711718_5 ATPases involved in chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 344.0
HFD1_k127_7711718_6 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 334.0
HFD1_k127_7711718_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000005388 245.0
HFD1_k127_7711718_8 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000001846 235.0
HFD1_k127_7711718_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000001772 179.0
HFD1_k127_7715960_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 GO:0000166,GO:0003674,GO:0003824,GO:0004362,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0015037,GO:0015038,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071949,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 593.0
HFD1_k127_7715960_1 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01576,K01652 - 2.2.1.6,4.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000003073 224.0
HFD1_k127_7715960_2 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000009091 201.0
HFD1_k127_7717270_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 7.885e-194 619.0
HFD1_k127_7717270_1 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 414.0
HFD1_k127_7717270_2 Phage shock protein C - - - 0.000001335 53.0
HFD1_k127_7722634_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 1.084e-240 753.0
HFD1_k127_7722634_1 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 552.0
HFD1_k127_7722634_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 412.0
HFD1_k127_7722634_3 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000016 233.0
HFD1_k127_7722634_4 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.000000000000000000000000000000000003303 148.0
HFD1_k127_7722634_5 Acyl carrier protein phosphodiesterase - - - 0.0000000000000000000000000000000004262 142.0
HFD1_k127_7722634_6 S4 RNA-binding domain K04762 GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009987,GO:0016070,GO:0033554,GO:0034605,GO:0034641,GO:0043021,GO:0043023,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.000000000000000000000000000000216 131.0
HFD1_k127_7722634_7 Haloacid dehalogenase-like hydrolase K20881 - 3.1.3.5 0.0000000000000000000008901 98.0
HFD1_k127_7731364_0 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000003653 203.0
HFD1_k127_7731364_1 Methylmuconolactone methyl-isomerase - - - 0.000000000000000000000000000000000108 141.0
HFD1_k127_7731364_2 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000000000001485 133.0
HFD1_k127_7731364_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000002584 119.0
HFD1_k127_7731364_4 4Fe-4S binding domain - - - 0.0000000008055 66.0
HFD1_k127_7741851_0 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.00000000000000000000000000000000000000000000000000000000000002478 238.0
HFD1_k127_7741851_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000003819 195.0
HFD1_k127_7743601_0 Bacterial extracellular solute-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 352.0
HFD1_k127_7743601_1 TIGRFAM sulfate ABC transporter K02046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008249 340.0
HFD1_k127_7743601_2 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008257 357.0
HFD1_k127_7743601_3 sulfate ABC transporter K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 304.0
HFD1_k127_7751615_0 PFAM Rieske 2Fe-2S domain protein - - - 0.000000000000000000000000000000000000000000000000001778 186.0
HFD1_k127_7751615_1 Membrane - - - 0.00000000000000000000000000000000000001219 150.0
HFD1_k127_7751615_2 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000000000000009676 124.0
HFD1_k127_7751615_3 GIY-YIG catalytic domain K07461 - - 0.00000000000000000002468 94.0
HFD1_k127_7751615_4 - - - - 0.000000000001161 73.0
HFD1_k127_7753984_0 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008636 274.0
HFD1_k127_7753984_1 COG2211 Na melibiose symporter and related transporters K03292,K16210 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006371 283.0
HFD1_k127_7753984_2 Acyl-CoA dehydrogenase, C-terminal domain K16047 - 1.14.14.12 0.000000000000000000000000004089 119.0
HFD1_k127_7753984_3 Autoinducer binding domain - - - 0.0000000000005231 77.0
HFD1_k127_776171_0 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 407.0
HFD1_k127_776171_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 369.0
HFD1_k127_776171_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000197 146.0
HFD1_k127_776171_3 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.000000000000000000000000000001539 130.0
HFD1_k127_7762586_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1078.0
HFD1_k127_7762586_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 332.0
HFD1_k127_7762586_2 containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006582 292.0
HFD1_k127_776586_0 Molecular chaperone. Has ATPase activity K04079 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006974,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0042623,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 - 4.457e-264 827.0
HFD1_k127_776586_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 497.0
HFD1_k127_776586_2 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564 2.1.1.298 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 329.0
HFD1_k127_776586_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 311.0
HFD1_k127_7771511_0 acyl-CoA transferases carnitine dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 366.0
HFD1_k127_7771511_1 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 303.0
HFD1_k127_7771511_2 N-terminal half of MaoC dehydratase K09709 - 4.2.1.153 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001448 284.0
HFD1_k127_7771511_3 - - - - 0.00000000000000000000000000000000000008257 144.0
HFD1_k127_7771797_0 peptidase S9 K01354 - 3.4.21.83 8.905e-198 641.0
HFD1_k127_7771797_1 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 406.0
HFD1_k127_7796090_0 siderophore transport K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 335.0
HFD1_k127_7810941_0 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 399.0
HFD1_k127_7810941_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 312.0
HFD1_k127_7810941_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 290.0
HFD1_k127_7815685_0 PFAM Rieske 2Fe-2S domain - - - 2.041e-198 629.0
HFD1_k127_7815685_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 360.0
HFD1_k127_7815685_2 cytochrome P-450 K21116 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009944 263.0
HFD1_k127_7815685_3 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 0.000000000000000000000000000000000000000000001348 171.0
HFD1_k127_7815685_4 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000000000000000000000000000000000003644 168.0
HFD1_k127_7815685_5 SnoaL-like domain - - - 0.00000000000000000000000000000000000005775 147.0
HFD1_k127_7815685_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000001867 148.0
HFD1_k127_7815685_7 Cupin domain - - - 0.000000000000000000000000000000006967 132.0
HFD1_k127_7820938_0 oligoendopeptidase F K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 534.0
HFD1_k127_7820938_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003507 267.0
HFD1_k127_7820938_2 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000883 201.0
HFD1_k127_7825966_0 MotA/TolQ/ExbB proton channel family - - - 0.000000000000000000000000000000000000000000000000000000004464 211.0
HFD1_k127_7825966_1 Dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000006261 196.0
HFD1_k127_7825966_2 Haemolysin-III related - - - 0.00000000000000000000000000000000000000000000000003287 185.0
HFD1_k127_7825966_3 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000003336 173.0
HFD1_k127_7825966_4 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000000000000002639 133.0
HFD1_k127_783193_0 histidyl-tRNA synthetase K01892 GO:0003674,GO:0003824,GO:0004812,GO:0004821,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006427,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 497.0
HFD1_k127_783193_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 463.0
HFD1_k127_783193_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000005274 225.0
HFD1_k127_783193_3 Tetratricopeptide repeat K02656 - - 0.00000000000000000000000000000000000000000000000000003348 197.0
HFD1_k127_783193_4 Tetratricopeptide repeat-like domain - - - 0.0000000000000000000000000005889 121.0
HFD1_k127_783193_5 Domain of unknown function (DUF4115) K15539 - - 0.0000000000000000000000001961 121.0
HFD1_k127_783193_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0005555 44.0
HFD1_k127_7833805_0 Involved in arsenical resistance. Thought to form the channel of an arsenite pump K03893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 512.0
HFD1_k127_7833805_1 FAD linked oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007844 359.0
HFD1_k127_7833805_2 Bacterial periplasmic substrate-binding proteins K09969 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007937 321.0
HFD1_k127_7833805_3 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000001835 128.0
HFD1_k127_7835334_0 PFAM Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 484.0
HFD1_k127_7835334_1 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000004907 90.0
HFD1_k127_7838436_0 Phospholipase D Active site motif K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 369.0
HFD1_k127_7838436_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 346.0
HFD1_k127_7838436_2 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001 276.0
HFD1_k127_7838436_3 Periplasmic or secreted lipoprotein - - - 0.00000000000000000008022 93.0
HFD1_k127_7838436_4 response regulator - - - 0.0000000000000001676 85.0
HFD1_k127_7839974_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K18688 - 6.2.1.42 2.736e-210 666.0
HFD1_k127_7839974_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 464.0
HFD1_k127_7839974_2 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 350.0
HFD1_k127_7839974_3 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 305.0
HFD1_k127_7839974_4 Protein of unknown function (DUF1499) - - - 0.00000000000000000000000000000000000000000007075 169.0
HFD1_k127_7839974_5 methyltransferase - - - 0.00000000000000000000000000000000005734 138.0
HFD1_k127_7839974_6 protein conserved in bacteria - - - 0.000000000000000005903 91.0
HFD1_k127_7860452_0 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 555.0
HFD1_k127_7860452_1 His Kinase A (phosphoacceptor) domain K07638 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 316.0
HFD1_k127_7860452_2 response regulator receiver K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 297.0
HFD1_k127_7860452_3 Belongs to the ompA family K03286 - - 0.000000000000000000000000000002684 129.0
HFD1_k127_7885101_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 374.0
HFD1_k127_7885101_1 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 301.0
HFD1_k127_7885101_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000002667 190.0
HFD1_k127_7885101_3 - - - - 0.000000000000000000000000000007447 123.0
HFD1_k127_7889590_0 Phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 374.0
HFD1_k127_7889590_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01928,K01929,K15792 - 6.3.2.10,6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009661 326.0
HFD1_k127_7889590_2 FMN-binding domain protein - - - 0.0000000000000000000000000000000000000009921 159.0
HFD1_k127_7889590_3 - - - - 0.00000000000000006819 90.0
HFD1_k127_7889590_4 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000005507 66.0
HFD1_k127_7889590_5 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000001249 59.0
HFD1_k127_789044_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family K02495 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004088 352.0
HFD1_k127_789044_1 PhoD-like phosphatase K01113 - 3.1.3.1 0.0000000000004755 76.0
HFD1_k127_789044_2 - - - - 0.00000000003888 74.0
HFD1_k127_7909974_0 Flavin-binding monooxygenase-like - - - 2.948e-276 857.0
HFD1_k127_7909974_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003499 421.0
HFD1_k127_7909974_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 410.0
HFD1_k127_7909974_3 Class II aldolase adducin family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 381.0
HFD1_k127_7909974_4 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 313.0
HFD1_k127_7909974_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000003975 221.0
HFD1_k127_7909974_6 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000004402 189.0
HFD1_k127_7909974_7 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000003236 177.0
HFD1_k127_7909974_8 - - - - 0.00000000000000000005409 97.0
HFD1_k127_7912004_0 SMART AAA ATPase K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 421.0
HFD1_k127_7912004_1 COG0840 Methyl-accepting chemotaxis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 370.0
HFD1_k127_7912004_2 aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005494 270.0
HFD1_k127_7912004_3 PFAM phospholipid glycerol acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001228 258.0
HFD1_k127_7912004_4 Type II secretion system protein B K02451 - - 0.00000000000000000674 94.0
HFD1_k127_7924417_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 398.0
HFD1_k127_7924417_1 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000005728 156.0
HFD1_k127_7924417_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000761 112.0
HFD1_k127_7945696_0 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000768 395.0
HFD1_k127_7945696_1 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000002079 264.0
HFD1_k127_7945696_2 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K03148,K21029 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0061605,GO:0070566,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.73,2.7.7.80 0.0000000000000000000000000000000000000000000000006831 177.0
HFD1_k127_7968481_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 340.0
HFD1_k127_7968481_1 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000004168 218.0
HFD1_k127_7968481_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000009956 212.0
HFD1_k127_7968481_3 PFAM secretion protein HlyD - - - 0.0000000000000000000000000000000000000000000000000000000001066 220.0
HFD1_k127_7973948_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2147.0
HFD1_k127_7973948_1 COG0493 NADPH-dependent glutamate synthase beta chain and K00266 - 1.4.1.13,1.4.1.14 1.42e-222 700.0
HFD1_k127_7973948_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000009695 100.0
HFD1_k127_7973948_3 Type II secretory pathway K03112 GO:0003674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0030428,GO:0032153,GO:0042834,GO:0044464,GO:0097367 - 0.0000000001346 71.0
HFD1_k127_7983041_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 5.116e-200 632.0
HFD1_k127_7983041_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 572.0
HFD1_k127_7983041_2 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 434.0
HFD1_k127_7983041_3 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000003798 193.0
HFD1_k127_7983041_4 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.0000000000000009198 85.0
HFD1_k127_7984839_0 PQQ-like domain K00117 - 1.1.5.2 6.205e-244 767.0
HFD1_k127_7984839_1 PFAM beta-lactamase domain protein K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 299.0
HFD1_k127_7984839_2 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000001182 146.0
HFD1_k127_7984839_3 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0002323 49.0
HFD1_k127_7999954_0 Anticodon binding domain K01880 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 529.0
HFD1_k127_7999954_1 Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily K07536 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 394.0
HFD1_k127_7999954_2 ubiE/COQ5 methyltransferase family - - - 0.000001171 52.0
HFD1_k127_7999954_3 - - - - 0.00005216 52.0
HFD1_k127_8007075_0 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 382.0
HFD1_k127_8007075_1 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004501 244.0
HFD1_k127_8007075_2 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000001302 201.0
HFD1_k127_8007075_3 Pfam:DUF385 - - - 0.00000000000000000000000000000007937 131.0
HFD1_k127_8015213_0 Transcriptional regulator with HTH domain and aminotransferase domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007841 508.0
HFD1_k127_8015213_1 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 393.0
HFD1_k127_8015213_2 hydrolase, family 3 K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000002638 247.0
HFD1_k127_8015213_3 of the drug metabolite transporter (DMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000033 252.0
HFD1_k127_8015213_4 PFAM major facilitator superfamily MFS_1 K03292 - - 0.000000000000000003987 94.0
HFD1_k127_821420_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 608.0
HFD1_k127_821420_1 Peptidoglycan polymerase that is essential for cell division K03588 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505 - 0.00000000000000000000000000000000000000000000000000000000000000000000003132 246.0
HFD1_k127_821420_2 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - 0.000000000000005132 82.0
HFD1_k127_822379_0 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 507.0
HFD1_k127_822379_1 ankyrin repeat K15503 - - 0.00000000000000000000000000001527 134.0
HFD1_k127_845353_0 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 518.0
HFD1_k127_845353_1 ABC transporter, transmembrane region K06147,K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 310.0
HFD1_k127_853337_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions - - - 4.61e-267 831.0
HFD1_k127_853337_1 Carboxylesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 366.0
HFD1_k127_863811_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 437.0
HFD1_k127_863811_1 nadp-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009054 408.0
HFD1_k127_863811_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 380.0
HFD1_k127_863811_3 cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 378.0
HFD1_k127_863811_4 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001718 255.0
HFD1_k127_863811_5 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000004928 234.0
HFD1_k127_863811_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000002268 68.0
HFD1_k127_874746_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 3.827e-298 929.0
HFD1_k127_874746_1 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000002576 201.0
HFD1_k127_923558_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1156.0
HFD1_k127_923558_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000146 212.0
HFD1_k127_923558_2 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000001614 130.0
HFD1_k127_936665_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 3.267e-235 741.0
HFD1_k127_936665_1 Transfers a succinyl group from succinyl-CoA to L- serine, forming succinyl-L-serine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 430.0
HFD1_k127_936665_2 AIR synthase related protein, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 298.0
HFD1_k127_936665_3 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 299.0
HFD1_k127_936665_4 Protein-disulfide isomerase K07396 - - 0.0000000000000000000000001715 114.0
HFD1_k127_936665_5 Carboxylesterase family - - - 0.00000000000000000000569 92.0
HFD1_k127_948118_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 9.081e-245 785.0
HFD1_k127_948118_1 amidohydrolase - - - 3.182e-196 630.0
HFD1_k127_948118_10 COG1522 Transcriptional regulators K03718 - - 0.0000000000000000000002352 102.0
HFD1_k127_948118_11 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000002035 88.0
HFD1_k127_948118_12 Transcription regulator K03718 - - 0.0000000000000862 81.0
HFD1_k127_948118_13 hydrolase K01048 - 3.1.1.5 0.000000389 53.0
HFD1_k127_948118_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 485.0
HFD1_k127_948118_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 - 0.000000000000000000000000000000000000000000000000000000000000000001055 231.0
HFD1_k127_948118_4 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000001055 230.0
HFD1_k127_948118_5 MerR family regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000005102 205.0
HFD1_k127_948118_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000002846 183.0
HFD1_k127_948118_7 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000004287 158.0
HFD1_k127_948118_8 And related - - - 0.000000000000000000000000000000000004856 144.0
HFD1_k127_948118_9 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.00000000000000000000000000001026 134.0
HFD1_k127_949929_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 556.0
HFD1_k127_949929_1 FAD dependent oxidoreductase K09471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008546 445.0
HFD1_k127_949929_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K12256 - 2.6.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 434.0
HFD1_k127_949929_3 COG1177 ABC-type spermidine putrescine transport system, permease component II K11074 - - 0.00000000000000000000000000000000000000000000000000000000000000000217 229.0
HFD1_k127_952807_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 3.33e-218 698.0
HFD1_k127_952807_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000008951 98.0
HFD1_k127_956418_0 Selenoprotein B glycine betaine sarcosine D-proline reductase K10794 - 1.21.4.1 0.00000000000000000000000000000000000000000000000000000000002637 209.0
HFD1_k127_956418_1 - - - - 0.0000000000000000000000000000000000177 139.0
HFD1_k127_956418_2 dehydratase - - - 0.0000000003495 62.0
HFD1_k127_96010_0 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 394.0
HFD1_k127_96010_1 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 360.0
HFD1_k127_96010_2 Saccharopine dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001068 252.0
HFD1_k127_967676_0 of ABC transporters with duplicated ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 580.0
HFD1_k127_967676_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004077 305.0
HFD1_k127_967676_2 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000003296 162.0
HFD1_k127_967676_3 Pfam Pyridoxamine 5'-phosphate - - - 0.000000000000000000001566 108.0
HFD1_k127_975250_0 transport system, periplasmic component K13893 - - 9.6e-210 663.0
HFD1_k127_975250_1 Putative amidoligase enzyme (DUF2126) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 556.0
HFD1_k127_975250_2 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008264 429.0
HFD1_k127_975250_3 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007492 399.0
HFD1_k127_975976_0 Glutathione-dependent formaldehyde-activating enzyme K03396 - 4.4.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003753 280.0
HFD1_k127_975976_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001079 269.0
HFD1_k127_975976_2 PFAM Cell wall hydrolase, SleB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000213 254.0
HFD1_k127_975976_3 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000004496 210.0
HFD1_k127_975976_4 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000575 134.0
HFD1_k127_97881_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044262,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046487,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1241.0
HFD1_k127_97881_1 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000002421 214.0
HFD1_k127_97881_2 pyridoxamine 5'-phosphate - - - 0.00000000000000000000000000000000000000725 149.0
HFD1_k127_97881_3 phosphatase phosphohexomutase - - - 0.00000000000000000000000000000000000009348 151.0
HFD1_k127_97881_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000003983 142.0
HFD1_k127_984087_0 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004077 466.0
HFD1_k127_984087_1 cellulase activity - - - 0.0000000000000005327 86.0
HFD1_k127_996001_0 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000143 221.0
HFD1_k127_996001_1 AMP-binding enzyme C-terminal domain K16029 - - 0.000000000000000000000000000000000000000000000008088 180.0
HFD1_k127_996001_2 Enoyl-CoA hydratase carnithine racemase K15866 GO:0003674,GO:0003824,GO:0004300,GO:0005488,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0019395,GO:0019439,GO:0019748,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 5.3.3.18 0.0000000000000002518 84.0