logo

Overview

ID MAG01628
Name HFD1_bin.8
Sample SMP0043
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Burkholderiaceae
Genus Aquabacterium
Species Aquabacterium sp918741295
Assembly information
Completeness (%) 77.72
Contamination (%) 3.41
GC content (%) 64.0
N50 (bp) 4,590
Genome size (bp) 3,444,049

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3627

Gene name Description KEGG GOs EC E-value Score Sequence
HFD1_k127_1001217_0 Ami_3 K01448 - 3.5.1.28 1.485e-202 641.0
HFD1_k127_1001217_1 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 590.0
HFD1_k127_1001217_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005623 557.0
HFD1_k127_1001217_3 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 448.0
HFD1_k127_1001217_4 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 341.0
HFD1_k127_1001217_5 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004285 250.0
HFD1_k127_1001217_6 Serine threonine protein kinase K08282 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000002588 248.0
HFD1_k127_1001217_8 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000000000000000000000000008879 200.0
HFD1_k127_1001217_9 sequence-specific DNA binding - - - 0.000000000000000000000000000000000002044 140.0
HFD1_k127_1001230_0 CBS domain containing protein K07168 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 470.0
HFD1_k127_1001230_1 Predicted metal-dependent hydrolase K07044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007981 426.0
HFD1_k127_1001230_2 May be involved in recombination K03554 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 375.0
HFD1_k127_1001230_3 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000455 250.0
HFD1_k127_1001230_4 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000000000000000000000000000000008391 231.0
HFD1_k127_1003090_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007857 544.0
HFD1_k127_1003090_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 456.0
HFD1_k127_1003090_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 433.0
HFD1_k127_1003746_0 Cytochrome c K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 433.0
HFD1_k127_1003746_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000002159 185.0
HFD1_k127_1003746_2 - - - - 0.0000000000000000000000000000000000000000000001379 175.0
HFD1_k127_1013519_0 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009897 419.0
HFD1_k127_1013519_1 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 402.0
HFD1_k127_1013519_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 310.0
HFD1_k127_1013519_3 Zinc carboxypeptidase - - - 0.0000000000001126 82.0
HFD1_k127_1015549_0 VWA domain containing CoxE-like protein K09989 - - 5.148e-227 707.0
HFD1_k127_1015549_1 surface antigen K07278 - - 9.544e-220 701.0
HFD1_k127_1015549_2 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 528.0
HFD1_k127_1015549_3 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 494.0
HFD1_k127_1015549_4 cytochrome C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 323.0
HFD1_k127_1015549_5 TIGRFAM diguanylate cyclase K13069,K21085 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000002147 203.0
HFD1_k127_1015549_6 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000001395 93.0
HFD1_k127_1036309_0 SMART alpha amylase catalytic sub domain K05343 - 3.2.1.1,5.4.99.16 1.723e-287 899.0
HFD1_k127_1036309_1 Alkaline and neutral invertase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 573.0
HFD1_k127_1036309_2 PFAM Conserved TM helix repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003676 278.0
HFD1_k127_1036309_3 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001906 259.0
HFD1_k127_1036309_4 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000002305 184.0
HFD1_k127_1070059_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 2.447e-280 870.0
HFD1_k127_1070059_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 590.0
HFD1_k127_1070059_2 Aminotransferase class I and II K00832 - 2.6.1.57 0.0000000000005237 68.0
HFD1_k127_1070059_3 Receptor family ligand binding region K01999 - - 0.0000000000005248 69.0
HFD1_k127_1073186_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1225.0
HFD1_k127_1073186_1 PFAM Glycosyl transferase, family K00766 - 2.4.2.18 0.00000000000001348 77.0
HFD1_k127_1073186_2 Glycosyl transferase - GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.00001551 48.0
HFD1_k127_1093460_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 598.0
HFD1_k127_1093460_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009063 526.0
HFD1_k127_1093460_10 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000000000002378 182.0
HFD1_k127_1093460_11 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000000004863 142.0
HFD1_k127_1093460_12 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000000000000000002262 103.0
HFD1_k127_1093460_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007025 460.0
HFD1_k127_1093460_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 389.0
HFD1_k127_1093460_4 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 385.0
HFD1_k127_1093460_5 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 289.0
HFD1_k127_1093460_6 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009511 249.0
HFD1_k127_1093460_7 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000000000000000000000001526 217.0
HFD1_k127_1093460_8 Protein of unknown function (DUF962) - - - 0.0000000000000000000000000000000000000000000000000000001147 202.0
HFD1_k127_1093460_9 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000000000000000000000000000001497 189.0
HFD1_k127_1104714_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1146.0
HFD1_k127_1107947_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.541e-300 932.0
HFD1_k127_1107947_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000004227 221.0
HFD1_k127_1107947_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000000000000000000000000000005018 175.0
HFD1_k127_1107947_3 Transcriptional regulator - - - 0.0000000000113 68.0
HFD1_k127_1109520_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 8e-323 995.0
HFD1_k127_1109520_1 Rieske 2Fe-2S K00499 - 1.14.15.7 2.944e-228 709.0
HFD1_k127_1109520_2 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009804 449.0
HFD1_k127_1109520_3 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005877 284.0
HFD1_k127_1109520_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000000000000001554 119.0
HFD1_k127_1119449_0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 452.0
HFD1_k127_1119449_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 439.0
HFD1_k127_1119449_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 399.0
HFD1_k127_1119449_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 347.0
HFD1_k127_1119449_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 316.0
HFD1_k127_1132021_0 Protein of unknown function (DUF3683) - - - 0.0 1796.0
HFD1_k127_1132021_1 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 305.0
HFD1_k127_1132021_2 acyl carrier protein K02078 - - 0.0000000000000000000000000001674 119.0
HFD1_k127_1132021_3 membrane - - - 0.000000000000000000106 96.0
HFD1_k127_1135054_0 Belongs to the hyi family K01816,K22131 - 5.3.1.22,5.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 392.0
HFD1_k127_1135054_1 Serine aminopeptidase, S33 K01048 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 372.0
HFD1_k127_1135054_2 YaeQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 317.0
HFD1_k127_1135054_3 hemolysin activation secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000004182 241.0
HFD1_k127_1135054_4 Carboxylesterase family K03929 GO:0001503,GO:0001505,GO:0001507,GO:0001540,GO:0001649,GO:0002076,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0003990,GO:0004104,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005604,GO:0005605,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005794,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006581,GO:0006629,GO:0006644,GO:0006650,GO:0006656,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007155,GO:0007267,GO:0007268,GO:0007271,GO:0007275,GO:0007399,GO:0007416,GO:0007517,GO:0008144,GO:0008150,GO:0008152,GO:0008283,GO:0008291,GO:0008610,GO:0008654,GO:0009056,GO:0009058,GO:0009059,GO:0009611,GO:0009987,GO:0010646,GO:0010648,GO:0010817,GO:0012505,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0017144,GO:0017171,GO:0019538,GO:0019637,GO:0022607,GO:0022610,GO:0023051,GO:0023052,GO:0023057,GO:0030154,GO:0031012,GO:0032222,GO:0032223,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0033218,GO:0034641,GO:0034645,GO:0042133,GO:0042135,GO:0042136,GO:0042165,GO:0042166,GO:0042277,GO:0042445,GO:0042447,GO:0042562,GO:0042737,GO:0042802,GO:0042803,GO:0042982,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043236,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044420,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045017,GO:0045202,GO:0046470,GO:0046474,GO:0046483,GO:0046486,GO:0046983,GO:0048468,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048731,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050789,GO:0050794,GO:0050804,GO:0050805,GO:0050808,GO:0050840,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0052689,GO:0061061,GO:0062023,GO:0065007,GO:0065008,GO:0070201,GO:0070405,GO:0071704,GO:0071840,GO:0071944,GO:0090087,GO:0090304,GO:0090407,GO:0097164,GO:0098916,GO:0099177,GO:0099536,GO:0099537,GO:1900619,GO:1901360,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903530,GO:1903532,GO:1904951 - 0.0000000000000000000000008212 109.0
HFD1_k127_1139217_0 Flagellar protein FliT K02423 - - 0.0000000000000000000000000000000000000000000009989 167.0
HFD1_k127_1139217_1 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.000000000000000000000000000000000000000002729 158.0
HFD1_k127_1139217_2 flagellar protein FliS K02422 - - 0.0000000000000000000000000000000000001615 146.0
HFD1_k127_1139217_3 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.0000000000001738 78.0
HFD1_k127_1149413_0 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 GO:0003674,GO:0003824,GO:0004620,GO:0004630,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008081,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016298,GO:0016740,GO:0016772,GO:0016780,GO:0016787,GO:0016788,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 349.0
HFD1_k127_1149413_1 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009834 289.0
HFD1_k127_1149413_2 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.000000000000001057 79.0
HFD1_k127_1156558_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009233 498.0
HFD1_k127_1156558_1 cytochrome oxidase assembly K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 406.0
HFD1_k127_1156558_2 Belongs to the glucose-6-phosphate 1-epimerase family K01792 - 5.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 396.0
HFD1_k127_1156558_3 signal sequence binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 325.0
HFD1_k127_1156558_4 Protein of unknown function (DUF429) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 308.0
HFD1_k127_1156558_5 Electron transport protein SCO1 SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001978 274.0
HFD1_k127_1156558_6 SURF1-like protein K14998 - - 0.0000000000000000000000000000000000000000000000000002504 198.0
HFD1_k127_1156558_7 Protein of unknown function (DUF2909) - - - 0.000000000000000000000000002764 111.0
HFD1_k127_1163778_0 COG3170 Tfp pilus assembly protein FimV K08086 - - 2.721e-302 951.0
HFD1_k127_1163778_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 8.908e-256 790.0
HFD1_k127_1163778_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 5.985e-209 651.0
HFD1_k127_1163778_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000987 459.0
HFD1_k127_1163778_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006439 445.0
HFD1_k127_1163778_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 407.0
HFD1_k127_1163778_6 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000913 335.0
HFD1_k127_1171372_0 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009756 596.0
HFD1_k127_1171372_1 Allophanate hydrolase subunit 2 K01941 - 6.3.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000003948 264.0
HFD1_k127_117647_0 modulator of DNA gyrase K03568 - - 5.533e-287 885.0
HFD1_k127_117647_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 8.053e-257 794.0
HFD1_k127_117647_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004337 244.0
HFD1_k127_117647_11 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003312 241.0
HFD1_k127_117647_12 binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000000000000000000007362 233.0
HFD1_k127_117647_13 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000000000000000000000000446 231.0
HFD1_k127_117647_14 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000000000000000005567 229.0
HFD1_k127_117647_15 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000001459 233.0
HFD1_k127_117647_16 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000000000000000000008285 196.0
HFD1_k127_117647_17 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000000000000000001987 192.0
HFD1_k127_117647_18 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000000000000000000000000000000000006949 181.0
HFD1_k127_117647_19 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000000002356 149.0
HFD1_k127_117647_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 5.981e-205 638.0
HFD1_k127_117647_20 - - - - 0.0000000000000000000000000241 118.0
HFD1_k127_117647_21 Ribosomal protein L30 K02907 - - 0.000000000000000000006194 94.0
HFD1_k127_117647_22 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000005781 74.0
HFD1_k127_117647_3 alpha/beta hydrolase fold K01046 - 3.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 539.0
HFD1_k127_117647_4 Proteobacterial lipase chaperone protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 413.0
HFD1_k127_117647_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 374.0
HFD1_k127_117647_6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009824 331.0
HFD1_k127_117647_7 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 306.0
HFD1_k127_117647_8 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 291.0
HFD1_k127_117647_9 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000784 252.0
HFD1_k127_1182087_0 Acyl transferase domain in polyketide synthase (PKS) enzymes. - - - 0.0 1327.0
HFD1_k127_1182087_1 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 378.0
HFD1_k127_1182087_2 PFAM regulatory protein TetR - - - 0.00000000000000000003485 93.0
HFD1_k127_1185630_0 C-terminal domain of 1-Cys peroxiredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 394.0
HFD1_k127_1185630_1 Transcriptional - - - 0.000000000000000000000000000007149 127.0
HFD1_k127_1188793_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 8.613e-316 974.0
HFD1_k127_1188793_1 GMC family oxidoreductase - - - 5.042e-280 868.0
HFD1_k127_1188793_2 - - - - 0.00000000000000000000000000000000000000000000000000873 187.0
HFD1_k127_1188793_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000001119 158.0
HFD1_k127_1188793_4 - - - - 0.00000000000000003545 86.0
HFD1_k127_1196829_0 propionate catabolism operon regulatory protein K02688 - - 4.173e-276 858.0
HFD1_k127_1196829_1 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01841,K03417 - 4.1.3.30,5.4.2.9 0.000000000000000000000000000000002255 132.0
HFD1_k127_1212698_0 Predicted metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 381.0
HFD1_k127_1212698_1 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 321.0
HFD1_k127_1212698_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001826 261.0
HFD1_k127_1215278_0 Histidine kinase - - - 0.0 1158.0
HFD1_k127_1215278_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1120.0
HFD1_k127_1215278_10 response regulator K22010 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 301.0
HFD1_k127_1215278_11 CYTH K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004983 285.0
HFD1_k127_1215278_12 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001584 256.0
HFD1_k127_1215278_13 Protein of unknown function (DUF3460) - - - 0.0000000000000000000000000006703 113.0
HFD1_k127_1215278_2 histidine kinase A domain protein - - - 0.0 1090.0
HFD1_k127_1215278_3 Putative diguanylate phosphodiesterase - - - 2.17e-322 1002.0
HFD1_k127_1215278_4 Diguanylate cyclase K13590 - 2.7.7.65 1.283e-208 664.0
HFD1_k127_1215278_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 554.0
HFD1_k127_1215278_6 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 514.0
HFD1_k127_1215278_7 COG0500 SAM-dependent methyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007037 493.0
HFD1_k127_1215278_8 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 458.0
HFD1_k127_1215278_9 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 365.0
HFD1_k127_121946_0 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 497.0
HFD1_k127_121946_1 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 377.0
HFD1_k127_1220446_0 GGDEF domain - - - 9.554e-214 694.0
HFD1_k127_1220446_1 HDOD domain - - - 0.000000000000000000001219 100.0
HFD1_k127_1226539_0 Penicillin-binding protein 5, C-terminal domain K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 513.0
HFD1_k127_1226539_1 - - - - 0.0000000000000001867 83.0
HFD1_k127_1240208_0 Acetyl-CoA dehydrogenase C-terminal like K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 539.0
HFD1_k127_1240208_1 Enoyl-CoA hydratase/isomerase K20036 - 4.2.1.155 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008133 455.0
HFD1_k127_1240208_2 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 0.000000000000000000000000000000000000000008496 154.0
HFD1_k127_1241599_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0 1057.0
HFD1_k127_1241599_1 Cytochrome c oxidase subunit K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009116 340.0
HFD1_k127_1241599_2 cytochrome C oxidase K02258 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008576 310.0
HFD1_k127_1241599_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000003846 176.0
HFD1_k127_1241599_4 Protein of unknown function (DUF2970) - - - 0.000000000000000002446 87.0
HFD1_k127_1243708_0 TIGRFAM Undecaprenyl-phosphate glucose phosphotransferase K03606 - - 3.926e-273 845.0
HFD1_k127_1243708_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 551.0
HFD1_k127_1243708_2 protein conserved in bacteria K03690 - - 0.0000000000000000000000000000000000000000000000000000000000000000004684 233.0
HFD1_k127_1245968_0 peptide transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 525.0
HFD1_k127_1245968_1 OmpA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007126 344.0
HFD1_k127_1245968_2 Protein of unknown function (DUF2894) - - - 0.0000000000000000000000000000000000000000000000006947 186.0
HFD1_k127_1245968_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000002257 122.0
HFD1_k127_1270202_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0 1469.0
HFD1_k127_1299837_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 1.431e-228 714.0
HFD1_k127_1299837_1 - - - - 0.000000000000000000000000008084 111.0
HFD1_k127_1299837_2 PFAM Outer membrane efflux protein K12340 - - 0.00000002429 57.0
HFD1_k127_1312020_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 1.737e-258 803.0
HFD1_k127_1312020_1 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 437.0
HFD1_k127_1312020_2 Belongs to the methyltransferase superfamily K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 373.0
HFD1_k127_1312020_3 Protein of unknown function, DUF599 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 366.0
HFD1_k127_1319614_0 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 304.0
HFD1_k127_1319614_1 Histidine kinase internal region - - - 0.00000000000000000000000000000000000000000000002656 175.0
HFD1_k127_1319614_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000003098 159.0
HFD1_k127_1327025_0 Electron transfer flavoprotein, alpha subunit K03522 - - 1.676e-203 654.0
HFD1_k127_1327025_1 FAD binding domain K00313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 510.0
HFD1_k127_1327025_2 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 498.0
HFD1_k127_1327025_3 serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 345.0
HFD1_k127_1327025_4 May protect the nitrogenase Fe-Mo protein from oxidative damage K02595 - - 0.00000000000000000000000000000000000000002153 156.0
HFD1_k127_1344788_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 1.172e-203 635.0
HFD1_k127_1344788_1 Subtilase family K14645 - - 0.000000000000000000001045 99.0
HFD1_k127_1351659_0 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 553.0
HFD1_k127_1351659_1 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008651 319.0
HFD1_k127_1351659_2 uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000001967 258.0
HFD1_k127_1360142_0 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 1.189e-304 938.0
HFD1_k127_1365865_0 Transporter, hydrophobe amphiphile efflux-1 (HAE1) family K18902 - - 0.0 1386.0
HFD1_k127_1369266_0 LysM domain - - - 2.565e-194 612.0
HFD1_k127_1369266_1 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 489.0
HFD1_k127_1369266_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 491.0
HFD1_k127_1369266_3 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 500.0
HFD1_k127_1369266_4 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 421.0
HFD1_k127_1369266_5 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 377.0
HFD1_k127_1369266_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 286.0
HFD1_k127_1375560_0 Protein involved in oxidation-reduction process K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 593.0
HFD1_k127_1375560_1 Type II secretory pathway, component ExeA K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 513.0
HFD1_k127_1375560_2 Ser Thr phosphatase family protein K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 486.0
HFD1_k127_1375560_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000002278 235.0
HFD1_k127_1375560_4 Type II secretion system protein B K02451 - - 0.0000000000000000000000000000000000000003875 158.0
HFD1_k127_1375560_5 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.000000000000000000000000001388 130.0
HFD1_k127_1386138_0 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 1.702e-218 685.0
HFD1_k127_1386138_1 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000000000000000000003318 151.0
HFD1_k127_1386138_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000002258 90.0
HFD1_k127_1396594_0 Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate K01782,K01825 GO:0003674,GO:0003824,GO:0003857,GO:0004165,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0016860,GO:0016863,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 1.42e-247 769.0
HFD1_k127_1396594_1 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00632 GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.16 0.000000000000000000003175 93.0
HFD1_k127_1406105_0 Transport of potassium into the cell K03549 - - 0.0 1050.0
HFD1_k127_1406105_1 Glutamate-cysteine ligase K01919 - 6.3.2.2 3.136e-268 827.0
HFD1_k127_1406105_2 Ammonium Transporter K03320 - - 2.442e-247 768.0
HFD1_k127_1406105_3 Benzoate membrane transport protein K05782 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 544.0
HFD1_k127_1406105_4 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 529.0
HFD1_k127_1406105_5 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 442.0
HFD1_k127_1406105_6 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 304.0
HFD1_k127_1408311_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 554.0
HFD1_k127_1408311_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000007203 71.0
HFD1_k127_1418953_0 Spermidine synthase K00797 - 2.5.1.16 0.0 1114.0
HFD1_k127_1418953_1 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009074 487.0
HFD1_k127_1418953_2 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 418.0
HFD1_k127_1418953_4 PPIC-type PPIASE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 351.0
HFD1_k127_1418953_5 Copper chaperone PCu(A)C K09796 - - 0.00000000000000000000000000000000007527 137.0
HFD1_k127_1420995_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 604.0
HFD1_k127_1420995_1 TIGRFAM Drug resistance transporter Bcr CflA subfamily K07552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007394 479.0
HFD1_k127_1420995_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000001319 150.0
HFD1_k127_1431713_0 TIGRFAM polysaccharide chain length determinant protein, PEP-CTERM locus subfamily - - - 1.909e-209 663.0
HFD1_k127_1431713_1 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 535.0
HFD1_k127_1431713_2 AAA domain K08252,K16692 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 394.0
HFD1_k127_1431713_3 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 330.0
HFD1_k127_1431713_4 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003433 249.0
HFD1_k127_1431713_5 TIGRFAM PEP-CTERM system associated protein - - - 0.00000000002218 69.0
HFD1_k127_1442288_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.979e-196 616.0
HFD1_k127_1442288_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 380.0
HFD1_k127_1442288_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000003585 134.0
HFD1_k127_1503695_0 amine dehydrogenase activity - - - 6.136e-300 926.0
HFD1_k127_1503695_1 DEAD_2 K10844 - 3.6.4.12 1.478e-250 783.0
HFD1_k127_1503695_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006569 419.0
HFD1_k127_1512498_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1153.0
HFD1_k127_1512498_1 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 437.0
HFD1_k127_1512498_2 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 332.0
HFD1_k127_1512498_3 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000001862 266.0
HFD1_k127_1512498_4 Alpha beta hydrolase K07002 - - 0.00000000000000000000000000000000000000000000000000000000000000004776 229.0
HFD1_k127_1515876_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 556.0
HFD1_k127_1515876_1 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 424.0
HFD1_k127_1515876_2 Glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005314 351.0
HFD1_k127_1515876_3 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008579 332.0
HFD1_k127_1515876_4 - - - - 0.0000000000005399 77.0
HFD1_k127_1516888_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0 1049.0
HFD1_k127_1516888_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 2.909e-260 812.0
HFD1_k127_1516888_2 OsmC-like protein K07397 - - 0.00000000000000000000000000000000000000000000000000003978 189.0
HFD1_k127_1516888_3 - - - - 0.0000000000000015 85.0
HFD1_k127_1516888_4 Alpha beta hydrolase K14731 - 3.1.1.83 0.00000002945 55.0
HFD1_k127_1526459_0 Pfam:DUF2424 K03379,K18371,K21730 - 1.14.13.160,1.14.13.22,1.14.13.226 8.303e-233 732.0
HFD1_k127_1526459_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 578.0
HFD1_k127_1526459_2 Acetyl xylan esterase (AXE1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 571.0
HFD1_k127_1526459_3 Flavin-binding monooxygenase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 564.0
HFD1_k127_1526459_4 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 488.0
HFD1_k127_1526459_5 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 442.0
HFD1_k127_1526459_6 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000004637 174.0
HFD1_k127_1526459_7 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000718 76.0
HFD1_k127_1528446_0 response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 614.0
HFD1_k127_1528446_1 chemotaxis, protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006884 340.0
HFD1_k127_1528446_2 Type II secretory pathway, component ExeA K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000008122 225.0
HFD1_k127_1530414_0 FAD binding domain - - - 2.029e-215 681.0
HFD1_k127_1530414_1 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 315.0
HFD1_k127_1530414_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000202 203.0
HFD1_k127_1530414_3 PFAM fumarylacetoacetate (FAA) hydrolase K16856,K18336 - 4.3.2.3 0.00000000000000000000000000000000000000003937 152.0
HFD1_k127_1530414_4 PFAM regulatory protein TetR K22105 - - 0.00000000000000002059 84.0
HFD1_k127_1530919_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 454.0
HFD1_k127_1530919_1 Peptidase M48 K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 356.0
HFD1_k127_1530919_2 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 308.0
HFD1_k127_1530919_3 dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000000000004301 166.0
HFD1_k127_1530919_4 - - - - 0.000000000000000000000000006982 112.0
HFD1_k127_153545_0 diguanylate cyclase - - - 2.445e-236 756.0
HFD1_k127_153545_1 serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 478.0
HFD1_k127_153545_2 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007494 384.0
HFD1_k127_153545_3 RDD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007477 297.0
HFD1_k127_153545_4 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000007633 147.0
HFD1_k127_1535769_0 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 6.79e-197 619.0
HFD1_k127_1535769_1 Carboxyl transferase domain K13778 - 6.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 394.0
HFD1_k127_1537184_0 Histidine kinase K03407 GO:0003674,GO:0005488,GO:0005515,GO:0019904 2.7.13.3 0.0 1076.0
HFD1_k127_1537184_1 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 482.0
HFD1_k127_1537184_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 386.0
HFD1_k127_1537184_3 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001036 280.0
HFD1_k127_1537184_4 Cache_2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002835 234.0
HFD1_k127_1537184_5 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000000805 223.0
HFD1_k127_1537184_6 - - - - 0.0000000000000000000000000000000000000000000000000000000001165 207.0
HFD1_k127_1537184_7 HIT domain - - - 0.000000000000000000000000000000000000000000000001244 180.0
HFD1_k127_1537184_8 FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000005834 157.0
HFD1_k127_1543991_0 Belongs to the DEAD box helicase family K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 8.268e-226 712.0
HFD1_k127_1543991_1 Fatty acid desaturase K00496 - 1.14.15.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 601.0
HFD1_k127_1543991_2 Phosphotransferase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 527.0
HFD1_k127_1543991_3 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 431.0
HFD1_k127_1543991_4 Cupin K21747 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 315.0
HFD1_k127_1543991_5 Rubredoxin - - - 0.0000000000000000000000003006 105.0
HFD1_k127_155282_0 PFAM Cys Met metabolism K01740 - 2.5.1.49 6.625e-257 797.0
HFD1_k127_155282_1 Domain of unknown function (DUF1794) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008674 333.0
HFD1_k127_155282_2 TOBE domain - - - 0.00000000000000000000000000006383 118.0
HFD1_k127_155282_3 Protein of unknown function (DUF1624) - - - 0.00000000007303 63.0
HFD1_k127_1555893_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1712.0
HFD1_k127_1555893_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 5.612e-227 706.0
HFD1_k127_1555893_2 response regulator K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 351.0
HFD1_k127_1555893_3 Negative regulator of K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 289.0
HFD1_k127_1555893_4 - - - - 0.0000000000005399 74.0
HFD1_k127_1557201_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 7.739e-285 878.0
HFD1_k127_1557201_1 Cys/Met metabolism PLP-dependent enzyme K01760 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 336.0
HFD1_k127_1557201_2 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 311.0
HFD1_k127_1557201_3 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 307.0
HFD1_k127_1557201_4 Nudix N-terminal K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 292.0
HFD1_k127_1557201_5 PFAM Negative transcriptional regulator K07734 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003918 280.0
HFD1_k127_1557201_6 Protein of unknown function (DUF1304) K08987 - - 0.00000000000000000000000000000000000000000000007072 171.0
HFD1_k127_1557201_7 response regulator K11712 - - 0.000000000000000000000000000000000000006895 147.0
HFD1_k127_1582105_0 Belongs to the GARS family K01945 - 6.3.4.13 4.769e-254 786.0
HFD1_k127_1582105_1 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 590.0
HFD1_k127_1582105_2 TIGRFAM ribonuclease, Rne Rng family K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 436.0
HFD1_k127_1582105_3 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 420.0
HFD1_k127_1582105_4 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 299.0
HFD1_k127_1582105_5 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000000000000000000000000001605 265.0
HFD1_k127_1582105_6 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003612 265.0
HFD1_k127_1582105_7 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001131 256.0
HFD1_k127_1582105_8 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000002592 251.0
HFD1_k127_1582105_9 Bacterial protein of unknown function (DUF853) K06915 - - 0.00000000000000000000000000000000000000000000000000000169 193.0
HFD1_k127_1586723_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789 - - 0.0 1456.0
HFD1_k127_1586723_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 510.0
HFD1_k127_1586723_10 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789 - - 0.00000000000000000000000000000000000000000000000000000000000006762 219.0
HFD1_k127_1586723_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 446.0
HFD1_k127_1586723_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 441.0
HFD1_k127_1586723_4 Domain of unknown function (DUF3391) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 437.0
HFD1_k127_1586723_5 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 417.0
HFD1_k127_1586723_6 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 318.0
HFD1_k127_1586723_7 Polyhydroxyalkanoate synthesis repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009452 271.0
HFD1_k127_1586723_8 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003434 263.0
HFD1_k127_1586723_9 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000002426 236.0
HFD1_k127_1600910_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1346.0
HFD1_k127_1600910_1 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 340.0
HFD1_k127_1600910_2 Barstar (barnase inhibitor) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 328.0
HFD1_k127_1600910_3 Ribonuclease K01167 - 3.1.27.3 0.00000000000000000000000000000000000005979 147.0
HFD1_k127_1600910_4 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.0000000000328 64.0
HFD1_k127_1614288_0 cyclopropane-fatty-acyl-phospholipid synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001305 276.0
HFD1_k127_1614288_1 DUF based on E. rectale Gene description (DUF3880) - - - 0.0005755 51.0
HFD1_k127_161464_0 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 378.0
HFD1_k127_161464_1 PaaX-like protein C-terminal domain K02616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 286.0
HFD1_k127_161464_2 Type II transport protein GspH K08084 - - 0.000000000000000000000000000000009527 134.0
HFD1_k127_161688_0 Peptidase dimerisation domain - - - 2.212e-212 665.0
HFD1_k127_161688_1 CHASE3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 407.0
HFD1_k127_161688_2 Tryptophan halogenase K21401 - 1.3.99.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 376.0
HFD1_k127_161688_3 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.0000000000000000000000000004292 118.0
HFD1_k127_1622965_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1114.0
HFD1_k127_1622965_1 dienelactone hydrolase K21104 - 3.1.1.101 0.00000000000000000000000000000000000000000000000000000000000000127 226.0
HFD1_k127_1639371_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 567.0
HFD1_k127_1639371_1 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 552.0
HFD1_k127_1639371_10 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000005151 98.0
HFD1_k127_1639371_11 Ribosomal protein L17 K02879 - - 0.0000000000000961 71.0
HFD1_k127_1639371_12 - - - - 0.000000005031 60.0
HFD1_k127_1639371_2 Alpha beta hydrolase K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 501.0
HFD1_k127_1639371_3 Metal-dependent hydrolase K07044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 404.0
HFD1_k127_1639371_4 Protein of unknown function (DUF2946) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005626 279.0
HFD1_k127_1639371_5 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004243 243.0
HFD1_k127_1639371_6 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000005789 228.0
HFD1_k127_1639371_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000002818 218.0
HFD1_k127_1639371_8 - - - - 0.00000000000000000000000000000000003417 149.0
HFD1_k127_1639371_9 Zinc-finger domain - - - 0.000000000000000000000000000003656 120.0
HFD1_k127_1648063_0 Nucleotidyl transferase K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 616.0
HFD1_k127_1648063_1 epimerase dehydratase K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 543.0
HFD1_k127_1648063_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000001554 248.0
HFD1_k127_1648063_3 Protein of unknown function (DUF1800) - - - 0.0000000004727 63.0
HFD1_k127_1658329_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 292.0
HFD1_k127_1658329_2 DoxX K15977 - - 0.00000001095 61.0
HFD1_k127_1665047_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 1.417e-277 863.0
HFD1_k127_1665047_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 4.439e-247 790.0
HFD1_k127_1665047_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 4.263e-238 738.0
HFD1_k127_1665047_3 Peptidoglycan polymerase that is essential for cell division K03588 - - 2.301e-216 685.0
HFD1_k127_1665047_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000008129 224.0
HFD1_k127_1668191_0 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 428.0
HFD1_k127_1668191_1 RmuC family K09760 - - 0.0000000002747 61.0
HFD1_k127_1668191_2 diguanylate cyclase - - - 0.00005423 56.0
HFD1_k127_1676507_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 3.222e-211 664.0
HFD1_k127_1692538_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1158.0
HFD1_k127_1692538_1 Glyoxalase-like domain K01759 - 4.4.1.5 0.00000000000000000000000000000000000000008359 152.0
HFD1_k127_1697398_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 531.0
HFD1_k127_1697398_1 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 451.0
HFD1_k127_1697398_2 Domain of unknown function (DUF4347) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 454.0
HFD1_k127_1697398_3 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 389.0
HFD1_k127_1697398_4 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009731 332.0
HFD1_k127_1697398_5 CHASE - - - 0.00000000000000000000000000000000000000000000000000000000000000242 227.0
HFD1_k127_1702876_0 Purine nucleoside permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 484.0
HFD1_k127_1702876_1 G T U mismatch-specific DNA glycosylase K03649 - 3.2.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000264 249.0
HFD1_k127_1702876_2 Purine nucleoside permease (NUP) - - - 0.00000000000000000000000000006754 133.0
HFD1_k127_170620_0 acyl-CoA dehydrogenase K20035 - - 1.389e-314 968.0
HFD1_k127_170620_1 Electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 514.0
HFD1_k127_170620_2 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 437.0
HFD1_k127_1707869_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 7.472e-284 874.0
HFD1_k127_1707869_1 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 280.0
HFD1_k127_1718557_0 glutamine synthetase K01915 - 6.3.1.2 1.958e-228 709.0
HFD1_k127_1718557_1 Glutamine amidotransferase domain K22081 - 2.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 527.0
HFD1_k127_1722236_0 Serine/threonine phosphatases, family 2C, catalytic domain K12132 - 2.7.11.1 4.691e-300 927.0
HFD1_k127_1722236_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 529.0
HFD1_k127_1722236_3 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004985 241.0
HFD1_k127_1722236_4 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000001837 203.0
HFD1_k127_1729383_0 Helicase K03657 - 3.6.4.12 1.638e-249 773.0
HFD1_k127_1729383_2 Peptidase family M48 - - - 0.000000000006308 70.0
HFD1_k127_1729383_3 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000000003205 60.0
HFD1_k127_1738605_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.108e-253 782.0
HFD1_k127_1738605_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006183 443.0
HFD1_k127_1738605_2 NADH dehydrogenase K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006262 274.0
HFD1_k127_1739764_0 Domain of unknown function (DUF1989) K09967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 429.0
HFD1_k127_1739764_1 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 409.0
HFD1_k127_1739764_2 Domain of unknown function (DUF1989) K09967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 393.0
HFD1_k127_1739764_3 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006143 379.0
HFD1_k127_1744247_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 6.845e-251 781.0
HFD1_k127_1744247_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 606.0
HFD1_k127_1744247_2 PFAM Aminotransferase class I and II K05825 - - 0.00000000000000000000000000000000001428 138.0
HFD1_k127_1744247_3 - - - - 0.00000000000000000000341 94.0
HFD1_k127_1744247_4 Domain of unknown function (DUF4404) - - - 0.0000000000000000002035 90.0
HFD1_k127_1748184_0 Flagellar protein export ATPase FliI K02412 - 3.6.3.14 1.922e-261 809.0
HFD1_k127_1748184_1 Flagellar assembly protein FliH K02411 - - 0.000000000000000000000000000000002798 134.0
HFD1_k127_175875_0 Transcriptional regulator, LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 456.0
HFD1_k127_175875_1 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 386.0
HFD1_k127_175875_2 DnaJ molecular chaperone homology domain K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 360.0
HFD1_k127_175875_3 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 351.0
HFD1_k127_175875_4 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000003556 203.0
HFD1_k127_175875_5 MerR HTH family regulatory protein K18997 - - 0.00000000000000000000001465 104.0
HFD1_k127_1759885_0 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 625.0
HFD1_k127_1759885_1 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 288.0
HFD1_k127_1759885_2 Protein of unknown function (DUF4255) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004815 286.0
HFD1_k127_1759885_3 Phage tail sheath C-terminal domain K06907 - - 0.0000000000000000000000000000000000000000000000000000003247 194.0
HFD1_k127_1759885_4 - - - - 0.0000000000000000000000000000000001697 142.0
HFD1_k127_1767276_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1658.0
HFD1_k127_1767276_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 502.0
HFD1_k127_1767276_2 Universal stress protein - - - 0.000000000000000000000000000000000000000000000000000000000000000005278 228.0
HFD1_k127_1767276_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000001641 172.0
HFD1_k127_1767276_4 Bacterial protein of unknown function (DUF883) - - - 0.0000000000000000000000000000000000003524 142.0
HFD1_k127_1767276_5 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000000000000002056 87.0
HFD1_k127_1773069_0 Aminotransferase class I and II K14261 - - 3.366e-241 746.0
HFD1_k127_1773069_1 PFAM CoA-binding domain protein K09181 - - 9.083e-240 750.0
HFD1_k127_1786465_0 Beta-ketoacyl synthase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 286.0
HFD1_k127_1786465_1 dehydratase - - - 0.000000000000000000000000000000000000000000000002993 179.0
HFD1_k127_1786465_2 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000001258 144.0
HFD1_k127_1793441_0 Ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 484.0
HFD1_k127_1793441_1 Cupin 2, conserved barrel domain protein K15539 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 335.0
HFD1_k127_1793441_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000001946 189.0
HFD1_k127_1797843_0 acetolactate synthase K01652 - 2.2.1.6 1.892e-253 789.0
HFD1_k127_1797843_1 citrate synthase K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 353.0
HFD1_k127_1797843_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007669 332.0
HFD1_k127_1797843_3 Subtilase family K14645 - - 0.000000000000000000000000000003861 128.0
HFD1_k127_1799788_0 PFAM Integrase catalytic - - - 1.395e-268 834.0
HFD1_k127_1799788_1 Evidence 2b Function of strongly homologous gene - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009448 405.0
HFD1_k127_1814240_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 473.0
HFD1_k127_1814240_1 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 368.0
HFD1_k127_1824177_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 353.0
HFD1_k127_1824177_1 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 293.0
HFD1_k127_1828739_0 Secretory lipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 319.0
HFD1_k127_1828739_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002139 231.0
HFD1_k127_1849232_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 610.0
HFD1_k127_1849232_1 CHASE3 domain K05962 - 2.7.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 422.0
HFD1_k127_1849232_2 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 351.0
HFD1_k127_1849232_3 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000001345 162.0
HFD1_k127_1849232_4 BON domain K04065 - - 0.00000000000000000000000000000034 128.0
HFD1_k127_1849232_5 FeoA K04758 - - 0.000000000000000000000000000002643 121.0
HFD1_k127_1849232_6 UPF0391 membrane protein - - - 0.000000000006072 68.0
HFD1_k127_1852399_0 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 345.0
HFD1_k127_1852399_1 Protein of unknown function (DUF3485) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002318 265.0
HFD1_k127_1852399_2 chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001098 260.0
HFD1_k127_1852399_3 PPIC-type PPIASE domain - - - 0.0000000000000000000000000000000000000000000000000000000003492 211.0
HFD1_k127_1852399_4 Chromate transporter K07240 - - 0.000000000000000000000000000000000001278 147.0
HFD1_k127_1854001_0 FIST_C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 579.0
HFD1_k127_1854001_1 - - - - 0.000000000006163 71.0
HFD1_k127_1878462_0 Pyridine nucleotide-disulphide oxidoreductase K05297,K12265 - 1.18.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 331.0
HFD1_k127_1878462_1 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 288.0
HFD1_k127_1878462_2 rubredoxin - - - 0.0000000000000000000000000898 106.0
HFD1_k127_1897417_0 COG0744 Membrane carboxypeptidase (penicillin-binding protein) - - - 2.012e-318 998.0
HFD1_k127_1897417_1 Starch synthase catalytic domain - - - 0.000000001405 61.0
HFD1_k127_1907082_0 GTP cyclohydrolase N terminal - - - 6.103e-216 674.0
HFD1_k127_1907082_1 Eukaryotic integral membrane protein (DUF1751) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 295.0
HFD1_k127_1907082_2 EamA-like transporter family - - - 0.00000000000000000002218 91.0
HFD1_k127_1914415_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000496 349.0
HFD1_k127_1914415_2 KR domain K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 312.0
HFD1_k127_1914415_3 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 303.0
HFD1_k127_1914415_4 RNA-binding protein - - - 0.000000000000000000000000000000000000000000000000002018 186.0
HFD1_k127_1914415_5 Belongs to the UPF0225 family K09858 - - 0.000000000000000000000000000000000000000000000000004136 192.0
HFD1_k127_1914415_6 Fe-S-cluster oxidoreductase K06940 - - 0.000000000000000000000000000000000000003072 148.0
HFD1_k127_1919617_0 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 469.0
HFD1_k127_1919617_1 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006314 355.0
HFD1_k127_1919617_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001414 271.0
HFD1_k127_1925831_0 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 458.0
HFD1_k127_1925831_1 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000000000000000000000000002147 226.0
HFD1_k127_1925831_2 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000001001 229.0
HFD1_k127_1925831_3 - - - - 0.0000000000000000000000000006811 119.0
HFD1_k127_1925831_4 domain protein - - - 0.0000000000001765 71.0
HFD1_k127_1955705_0 NMT1-like family K02051,K15576,K22067 - - 6.866e-244 756.0
HFD1_k127_1955705_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.64e-200 628.0
HFD1_k127_1955705_2 Putative Na+/H+ antiporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 603.0
HFD1_k127_1955705_3 Voltage gated chloride channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 525.0
HFD1_k127_1955705_4 Nitrate ABC transporter K15552,K15577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 486.0
HFD1_k127_1955705_5 ATPases associated with a variety of cellular activities K02049,K15578 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 469.0
HFD1_k127_1955705_6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 465.0
HFD1_k127_1994113_0 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007559 379.0
HFD1_k127_1994113_1 Glycosyltransferase family 25 (LPS biosynthesis protein) - - - 0.0000000000000000000000000000000000000000000000004615 180.0
HFD1_k127_1994113_2 Histidine kinase - - - 0.0000004084 53.0
HFD1_k127_2005774_0 CHASE2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007643 425.0
HFD1_k127_2005774_1 FecR protein - - - 0.00000000000000000000000000000009678 130.0
HFD1_k127_2018211_0 TonB-dependent receptor plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007486 435.0
HFD1_k127_2018211_1 PepSY-associated TM region K00380 - 1.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 423.0
HFD1_k127_2018211_2 TonB-dependent receptor plug K02014 - - 0.00000000000000000000000000000000000000000000000000000000000008126 218.0
HFD1_k127_2030533_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K00249,K00294,K13821 - 1.2.1.88,1.3.8.7,1.5.5.2 0.0 1026.0
HFD1_k127_2030533_1 peptidylprolyl isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 372.0
HFD1_k127_2030533_2 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001659 268.0
HFD1_k127_2030533_3 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000001457 245.0
HFD1_k127_2030533_4 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000000000000001894 126.0
HFD1_k127_2033614_0 PFAM FAD linked oxidase domain protein K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 523.0
HFD1_k127_2033614_1 4Fe-4S dicluster domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 446.0
HFD1_k127_2033614_2 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 303.0
HFD1_k127_2034123_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 4.613e-223 719.0
HFD1_k127_2054157_0 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K01086,K03841 - 3.1.3.11,3.1.3.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 463.0
HFD1_k127_2054157_1 Phosphoribulokinase K00855 - 2.7.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005006 265.0
HFD1_k127_2054157_2 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001419 253.0
HFD1_k127_2055858_0 Carboxyl transferase domain K13778 - 6.4.1.5 3.965e-223 700.0
HFD1_k127_2055858_1 KR domain K13774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 477.0
HFD1_k127_2060315_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 577.0
HFD1_k127_2060315_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 464.0
HFD1_k127_2060315_2 Protein conserved in bacteria K09924 - - 0.0000000000000000000000000000000000000000000000000000001509 202.0
HFD1_k127_2062030_0 PFAM NnrS family protein K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 606.0
HFD1_k127_2062030_1 type II secretion system protein E K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 366.0
HFD1_k127_2062030_2 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001027 244.0
HFD1_k127_2064994_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.607e-219 694.0
HFD1_k127_2064994_1 Methyl-accepting chemotaxis protein K03406,K03776,K05874 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000198 254.0
HFD1_k127_2064994_2 Diguanylate cyclase - - - 0.0000000000858 63.0
HFD1_k127_2065038_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 1.687e-214 667.0
HFD1_k127_2065038_1 PFAM Phospholipid glycerol acyltransferase K05939 - 2.3.1.40,6.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 456.0
HFD1_k127_2065038_2 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 336.0
HFD1_k127_2065038_3 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 298.0
HFD1_k127_2065038_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002834 237.0
HFD1_k127_2067939_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 3.96e-236 736.0
HFD1_k127_2067939_1 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 358.0
HFD1_k127_2067939_2 Chalcone isomerase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003212 275.0
HFD1_k127_2073246_0 KaiC K08482 - - 2.835e-231 728.0
HFD1_k127_2073246_1 Histidine kinase K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000006295 247.0
HFD1_k127_2076888_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1026.0
HFD1_k127_2076888_1 FUSC-like inner membrane protein yccS - - - 6.632e-216 692.0
HFD1_k127_2076888_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 314.0
HFD1_k127_2076888_3 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000742 234.0
HFD1_k127_2076888_4 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000007674 220.0
HFD1_k127_2077012_0 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 393.0
HFD1_k127_2077012_1 Asparaginase K01424 - 3.5.1.1 0.00000000000000000000000000000000000000005346 155.0
HFD1_k127_2077226_0 methyl-accepting chemotaxis protein K03406,K03776,K05874 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009368 524.0
HFD1_k127_2077226_1 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 287.0
HFD1_k127_2077226_2 Chalcone isomerase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000001325 241.0
HFD1_k127_2077226_3 START domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001966 237.0
HFD1_k127_2077226_4 - - - - 0.0000000000000000724 81.0
HFD1_k127_2077226_5 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000216 86.0
HFD1_k127_2111706_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 611.0
HFD1_k127_2111706_1 Glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007796 307.0
HFD1_k127_2111706_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000927 149.0
HFD1_k127_2120465_0 PhoP regulatory network protein YrbL K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 451.0
HFD1_k127_2120465_1 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 403.0
HFD1_k127_2120465_2 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000002012 124.0
HFD1_k127_2120465_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000751 125.0
HFD1_k127_2130686_0 Multicopper oxidase K22348 - 1.16.3.3 6.908e-266 824.0
HFD1_k127_2130686_1 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 532.0
HFD1_k127_2130686_2 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.000000000000000000000007433 106.0
HFD1_k127_2130686_3 Heavy-metal-associated domain K07213 - - 0.000000000000007758 76.0
HFD1_k127_2136516_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000004331 246.0
HFD1_k127_2136516_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.000000000000000000000000000000000000000009911 160.0
HFD1_k127_2136516_2 Domain of unknown function (DUF4347) - - - 0.000000000000000000000000000000000000001229 157.0
HFD1_k127_2140339_0 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000002258 228.0
HFD1_k127_2140339_1 chlorophyll binding - - - 0.000000000005294 75.0
HFD1_k127_2143471_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 1.893e-211 674.0
HFD1_k127_2143471_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 581.0
HFD1_k127_2143471_2 HDOD domain K08282 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008488 414.0
HFD1_k127_2143471_3 Likely ribonuclease with RNase H fold. K06959 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008134 362.0
HFD1_k127_2143471_4 Likely ribonuclease with RNase H fold. K06959 - - 0.000000000000277 69.0
HFD1_k127_2150502_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 4.552e-293 929.0
HFD1_k127_2150502_1 Exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 362.0
HFD1_k127_2150502_2 Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates K08722 - 3.1.3.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 323.0
HFD1_k127_2150502_3 Protein of unknown function (DUF808) K09781 - - 0.000000000000000000000000002367 113.0
HFD1_k127_215280_0 Tripartite ATP-independent periplasmic transporter DctQ - - - 0.000000000000000000000000000000000000000000000000000000000000000001629 232.0
HFD1_k127_215280_1 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000000000000000000003348 228.0
HFD1_k127_215280_2 TRAP dicarboxylate transporter, DctM subunit K03299 - - 0.0000000000000000000000000000000000000000000000000000000000004342 218.0
HFD1_k127_215280_3 Putative phosphatase (DUF442) - - - 0.000000000000000000000000000000000000000000000000002983 183.0
HFD1_k127_215280_4 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000000000000000001054 134.0
HFD1_k127_2168109_0 Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 489.0
HFD1_k127_2168109_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 441.0
HFD1_k127_2168109_2 Belongs to the UPF0061 (SELO) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 398.0
HFD1_k127_2168109_3 Protein of unknown function (DUF455) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 347.0
HFD1_k127_2168109_4 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000001198 147.0
HFD1_k127_2169535_0 PFAM response regulator receiver K08083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 304.0
HFD1_k127_2169535_1 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 298.0
HFD1_k127_2169535_2 Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) K03414 - - 0.00000000000000000000000000000000000000000000000000001692 190.0
HFD1_k127_2179565_0 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 387.0
HFD1_k127_2179565_1 Bacterial regulatory proteins, tetR family K05501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 304.0
HFD1_k127_2179565_2 - - - - 0.000000000000000000000000000000000000000000002064 169.0
HFD1_k127_2179565_3 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000002491 140.0
HFD1_k127_2179565_4 PEP-CTERM motif - - - 0.0000002969 55.0
HFD1_k127_2186387_0 - - - - 0.0 1137.0
HFD1_k127_2186387_1 SNF2 family N-terminal domain - - - 0.0 1079.0
HFD1_k127_2186387_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000671 265.0
HFD1_k127_219981_0 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 8.252e-200 626.0
HFD1_k127_219981_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000001223 190.0
HFD1_k127_219981_2 aminopeptidase N K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000002738 167.0
HFD1_k127_219981_3 - - - - 0.0001254 46.0
HFD1_k127_2214138_0 AA-adenyl-dom amino acid adenylation domain protein - - - 0.0 1060.0
HFD1_k127_2214138_1 PFAM Alpha beta hydrolase fold-3 domain protein K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 379.0
HFD1_k127_2214138_2 TonB dependent receptor K02014 - - 0.0000001166 54.0
HFD1_k127_2224298_0 acyl-CoA dehydrogenase - - - 1.311e-220 688.0
HFD1_k127_2224298_1 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 591.0
HFD1_k127_2224298_2 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 497.0
HFD1_k127_2224298_3 Sigma-54 interaction domain K02481,K10126,K10941 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 487.0
HFD1_k127_2224298_4 PFAM Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 370.0
HFD1_k127_2224298_5 gag-polyprotein putative aspartyl protease K06985 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 286.0
HFD1_k127_2224298_6 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002719 258.0
HFD1_k127_2242217_0 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 589.0
HFD1_k127_2242217_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 573.0
HFD1_k127_2242217_2 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000002361 203.0
HFD1_k127_2246669_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 8.153e-203 635.0
HFD1_k127_2246669_1 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 416.0
HFD1_k127_2246669_2 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008179 327.0
HFD1_k127_2246669_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005867 260.0
HFD1_k127_2246669_4 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000001575 165.0
HFD1_k127_2246669_5 PEP-CTERM motif - - - 0.0000000000000000000000000000000000000006595 155.0
HFD1_k127_2252147_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.346e-222 694.0
HFD1_k127_2252147_1 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000003668 119.0
HFD1_k127_2259810_0 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005382 242.0
HFD1_k127_2259810_1 Diguanylate cyclase with PAS PAC - - - 0.0000000000000000000000000000000005771 148.0
HFD1_k127_2259810_2 His Kinase A (phosphoacceptor) domain K11527 - 2.7.13.3 0.00000000000002875 86.0
HFD1_k127_2273445_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 2.995e-214 668.0
HFD1_k127_2273445_1 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000568 265.0
HFD1_k127_2275502_0 Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 375.0
HFD1_k127_2275502_1 Protein of unknown function (DUF3429) - - - 0.0000000000000000000000000000000000000000000000000000000000000002812 224.0
HFD1_k127_2275502_2 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000248 169.0
HFD1_k127_2275502_3 Peptidase M61 - - - 0.00000000000000000000000000000001636 132.0
HFD1_k127_2275555_0 Belongs to the GPI family K01810 - 5.3.1.9 1.151e-281 874.0
HFD1_k127_2275555_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 557.0
HFD1_k127_2275555_2 RNA polymerase sigma factor RpoH K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000576 518.0
HFD1_k127_2275555_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004211 503.0
HFD1_k127_2275555_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005774 351.0
HFD1_k127_2275555_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 345.0
HFD1_k127_2275555_6 Haloacid dehalogenase-like hydrolase K07025,K20866 - 3.1.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000009253 261.0
HFD1_k127_2275555_7 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000001104 118.0
HFD1_k127_2282387_0 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 3.107e-275 857.0
HFD1_k127_2282387_1 Belongs to the thiolase family K00626 - 2.3.1.9 1.401e-216 683.0
HFD1_k127_2282387_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.000000000000000000000000000000000000000000000000000001298 192.0
HFD1_k127_2282387_3 - - - - 0.000000000004115 67.0
HFD1_k127_2285470_0 Tetratricopeptide repeat - - - 8.167e-194 620.0
HFD1_k127_2285470_1 Outer membrane lipoprotein K02494 - - 0.000004427 54.0
HFD1_k127_2292383_0 Outer membrane efflux protein K18903 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 506.0
HFD1_k127_2292383_1 MMPL family K18138,K18902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001925 252.0
HFD1_k127_2311588_0 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 402.0
HFD1_k127_2311588_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000001022 171.0
HFD1_k127_2311588_2 Integral membrane protein (DUF2244) - - - 0.0000000000000000000000000000000000003655 146.0
HFD1_k127_2311588_3 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000005581 130.0
HFD1_k127_2329093_0 ANTAR domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 603.0
HFD1_k127_2329093_1 Formate/nitrite transporter K02598,K21993 - - 0.00000000000000000000000000000000000000000000007693 171.0
HFD1_k127_2334409_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 390.0
HFD1_k127_2341882_0 Nitrogenase molybdenum-iron protein, alpha K02586 - 1.18.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 600.0
HFD1_k127_2341882_1 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009362 578.0
HFD1_k127_2348377_0 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 433.0
HFD1_k127_2348377_1 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 310.0
HFD1_k127_2348377_2 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002724 261.0
HFD1_k127_2348377_3 - - - - 0.000000000000000000000000000000000000000000000005924 185.0
HFD1_k127_2348377_4 COG3210 Large exoproteins involved in heme utilization or adhesion - - - 0.000000000000000000000000000006486 129.0
HFD1_k127_2355625_0 TonB dependent receptor K16087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001998 287.0
HFD1_k127_2355625_1 PEP-CTERM motif - - - 0.0000000000000000000000000000000000000006265 157.0
HFD1_k127_2370424_0 LapD/MoxY periplasmic domain - - - 7.931e-287 893.0
HFD1_k127_2370424_1 TIGRFAM type I secretion outer membrane protein, TolC family K12543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005038 614.0
HFD1_k127_2370424_2 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 578.0
HFD1_k127_2370424_3 Male sterility protein K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 495.0
HFD1_k127_2370424_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 392.0
HFD1_k127_2370424_5 TIGRFAM type I secretion membrane fusion protein, HlyD family K12542 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006489 354.0
HFD1_k127_2370424_6 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 300.0
HFD1_k127_2386870_0 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 458.0
HFD1_k127_2386870_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007761 363.0
HFD1_k127_2386870_2 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 299.0
HFD1_k127_2386870_3 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.00000000000000000000000000000000000000000000000000000000001373 216.0
HFD1_k127_2386870_4 - - - - 0.0000000000000000000000000000000000000000167 161.0
HFD1_k127_2386870_5 ParD-like antitoxin of type II bacterial toxin-antitoxin system - - - 0.000000000000000000000000000000001362 132.0
HFD1_k127_2414300_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1097.0
HFD1_k127_2414300_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14392 - - 1.982e-253 787.0
HFD1_k127_2414300_2 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 582.0
HFD1_k127_2414300_3 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 530.0
HFD1_k127_2414300_4 Endonuclease Exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 462.0
HFD1_k127_2414300_5 Curli production assembly/transport component CsgG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 411.0
HFD1_k127_2414300_6 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 334.0
HFD1_k127_2414300_7 Nudix hydrolase K08310 - 3.6.1.67 0.000000000000000000000000000000000000000000000000000000000000000000000000000001019 265.0
HFD1_k127_2414300_8 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.0000000000000000000000000000000000000002571 153.0
HFD1_k127_2414300_9 Regulatory protein, FmdB family - - - 0.000000000000000000000000000000001253 133.0
HFD1_k127_2417814_0 Alcohol dehydrogenase GroES domain protein K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 532.0
HFD1_k127_2417814_1 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000004469 183.0
HFD1_k127_2417814_2 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000003847 139.0
HFD1_k127_2417814_3 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000001193 116.0
HFD1_k127_2433057_0 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 3.185e-198 622.0
HFD1_k127_2433057_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 362.0
HFD1_k127_2433057_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000000000000000001877 196.0
HFD1_k127_2433057_3 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.000000000000000000000000000000007234 134.0
HFD1_k127_2442837_0 Protein of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 453.0
HFD1_k127_2442837_1 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000002277 139.0
HFD1_k127_2454613_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1246.0
HFD1_k127_2454613_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1217.0
HFD1_k127_2454613_2 Phosphoesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 598.0
HFD1_k127_2454613_3 - - - - 0.000000000000000000000000008084 111.0
HFD1_k127_2454613_4 response to copper ion - - - 0.00000000506 63.0
HFD1_k127_2464583_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.332e-230 720.0
HFD1_k127_2464583_1 Predicted metal-dependent hydrolase K07044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 430.0
HFD1_k127_2472756_0 Phospholipase A1 K01058 - 3.1.1.32,3.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007893 368.0
HFD1_k127_2472756_1 Papain family cysteine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000002175 230.0
HFD1_k127_2472756_2 MlaD protein K06192 - - 0.0000000000000000000000000000000000000000000000000000000000005162 224.0
HFD1_k127_2472756_3 abc transporter atp-binding protein K02065 - - 0.0000000000000000000000000000000000000000000009531 167.0
HFD1_k127_2472756_4 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000009906 168.0
HFD1_k127_2472756_5 Protein of unknown function (DUF3309) - - - 0.00000000000000000009013 91.0
HFD1_k127_2472756_6 - - - - 0.00000000000000015 82.0
HFD1_k127_2472756_7 ABC-type transport auxiliary lipoprotein component - - - 0.0000000001619 71.0
HFD1_k127_2472756_8 - - - - 0.00003125 52.0
HFD1_k127_2476235_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 5.777e-310 960.0
HFD1_k127_2476235_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 425.0
HFD1_k127_2476235_2 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000000000000000000000000000000002259 224.0
HFD1_k127_2476235_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000000000000000000000000000009998 126.0
HFD1_k127_2476235_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000006078 100.0
HFD1_k127_2481453_0 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 400.0
HFD1_k127_2481453_1 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000001057 262.0
HFD1_k127_2481453_2 Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000003234 126.0
HFD1_k127_2481453_3 Belongs to the UPF0434 family K09791 - - 0.0000000000000000000000111 103.0
HFD1_k127_248536_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 3.428e-301 937.0
HFD1_k127_248536_1 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 4.66e-230 725.0
HFD1_k127_248536_10 Thioredoxin K03671 - - 0.00000000000000000000000000000000000005881 148.0
HFD1_k127_248536_11 Protein with unknown function (DUF469) K09923 - - 0.00000000000000000000000000000000001255 139.0
HFD1_k127_248536_12 gluconolactonase - - - 0.000000000000000000000000000000001502 132.0
HFD1_k127_248536_13 - - - - 0.00000000000000000000000000006085 122.0
HFD1_k127_248536_15 ribosome binding - - - 0.00004286 49.0
HFD1_k127_248536_2 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008464 533.0
HFD1_k127_248536_3 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 432.0
HFD1_k127_248536_4 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007375 397.0
HFD1_k127_248536_5 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002904 269.0
HFD1_k127_248536_6 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000005044 246.0
HFD1_k127_248536_7 PFAM CreA family protein K05805 - - 0.000000000000000000000000000000000000000000000000000000000000000000004921 239.0
HFD1_k127_248536_8 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.000000000000000000000000000000000000000000000000003947 194.0
HFD1_k127_248536_9 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000009831 187.0
HFD1_k127_248744_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 4.224e-202 632.0
HFD1_k127_248744_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003 272.0
HFD1_k127_248744_2 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003744 247.0
HFD1_k127_248744_3 - - - - 0.00000000000000000000002374 104.0
HFD1_k127_2488377_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 557.0
HFD1_k127_2488377_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 392.0
HFD1_k127_2488377_2 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000001638 240.0
HFD1_k127_2488377_3 - - - - 0.000000000000000000000000000000000000000000000000000000002323 210.0
HFD1_k127_2489281_0 Belongs to the universal stress protein A family - - - 1.964e-224 703.0
HFD1_k127_2489281_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 397.0
HFD1_k127_2489281_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009963 354.0
HFD1_k127_2489281_3 H-NS histone family K03746 - - 0.000000000000000000000000001434 114.0
HFD1_k127_2489281_4 Response regulator receiver - - - 0.000000000000000000002577 111.0
HFD1_k127_2489281_5 - - - - 0.000000000001059 76.0
HFD1_k127_2489281_6 - - - - 0.0004125 51.0
HFD1_k127_2489330_0 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 289.0
HFD1_k127_2489330_1 Uncharacterised protein family (UPF0149) K07039 - - 0.0000000000000000000000000000000000001268 151.0
HFD1_k127_2489330_2 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.000000000000000000000000002857 111.0
HFD1_k127_2510725_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.203e-229 716.0
HFD1_k127_2510725_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 400.0
HFD1_k127_2510725_2 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001256 275.0
HFD1_k127_2513746_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681,K20455 - 4.2.1.117,4.2.1.3 0.0 1645.0
HFD1_k127_2513746_1 protein conserved in bacteria K09788 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016853,GO:0016860,GO:0016863,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046459,GO:0071704,GO:0072329,GO:1901575 - 1.461e-215 681.0
HFD1_k127_2513746_2 Belongs to the citrate synthase family K01659 - 2.3.3.5 2.75e-196 612.0
HFD1_k127_2513746_3 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 558.0
HFD1_k127_2513746_4 Signal peptide protein - - - 0.0000000000000000000007711 104.0
HFD1_k127_251529_0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III K16872 - 2.3.1.207 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 437.0
HFD1_k127_251529_1 Acyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 407.0
HFD1_k127_251529_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000978 285.0
HFD1_k127_251529_3 2'-5' RNA ligase superfamily K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000000000000000000000000003826 239.0
HFD1_k127_251529_4 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.0000000000001187 71.0
HFD1_k127_2522176_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1038.0
HFD1_k127_2522176_1 Rhomboid family - - - 0.0000000000000000000000000000000003953 143.0
HFD1_k127_2522176_2 PPIC-type PPIASE domain - - - 0.00000000000000000000000000001148 121.0
HFD1_k127_2544830_0 Amidohydrolase family K01485 - 3.5.4.1 1.999e-235 734.0
HFD1_k127_2544830_1 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 517.0
HFD1_k127_2544830_2 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 383.0
HFD1_k127_2544830_3 Resolvase - - - 0.00004046 47.0
HFD1_k127_2557109_0 MMPL family - - - 1.702e-230 738.0
HFD1_k127_2557109_1 Bacterial lipid A biosynthesis acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 333.0
HFD1_k127_2557109_2 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.000000000000000000000000000000000000000000000000000102 194.0
HFD1_k127_2557109_3 Outer membrane lipoprotein carrier protein LolA - - - 0.000000000000000000000000000000000000000000000000003707 190.0
HFD1_k127_2557109_4 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000005564 164.0
HFD1_k127_2557109_5 FabA-like domain - - - 0.000000000000000007667 87.0
HFD1_k127_2566666_0 Belongs to the UPF0246 family K09861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 442.0
HFD1_k127_2566666_1 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 385.0
HFD1_k127_2566666_2 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004359 288.0
HFD1_k127_2566666_3 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000089 68.0
HFD1_k127_2566666_4 - - - - 0.00001418 50.0
HFD1_k127_2569688_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009937 471.0
HFD1_k127_2573181_0 Molecular chaperone. Has ATPase activity K04079 - - 0.0 1083.0
HFD1_k127_2573181_1 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 335.0
HFD1_k127_2581377_0 TIGRFAM type VI secretion protein IcmF K11891 - - 1.708e-277 881.0
HFD1_k127_2601066_0 pfkB family carbohydrate kinase K00852,K00856 - 2.7.1.15,2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 449.0
HFD1_k127_2601066_1 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000004091 150.0
HFD1_k127_2601066_2 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.0000000000000000000000000001565 114.0
HFD1_k127_2612337_0 Allophanate hydrolase subunit 2 K01941 - 6.3.4.6 1.416e-293 906.0
HFD1_k127_261373_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 2.538e-198 627.0
HFD1_k127_261373_1 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000893 250.0
HFD1_k127_2617958_0 - - - - 0.0 1178.0
HFD1_k127_2617958_1 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000002208 235.0
HFD1_k127_2617958_2 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000007942 183.0
HFD1_k127_2617958_3 tryptophan synthase subunit beta - - - 0.00000000000000000000000001382 111.0
HFD1_k127_262199_0 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007357 445.0
HFD1_k127_262199_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 329.0
HFD1_k127_262199_2 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000001593 211.0
HFD1_k127_262199_3 - - - - 0.000000000003094 75.0
HFD1_k127_263117_0 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 499.0
HFD1_k127_263117_1 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000000000000000000000002466 204.0
HFD1_k127_2664595_0 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 372.0
HFD1_k127_2664595_1 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 369.0
HFD1_k127_2664595_2 Nucleotidyl transferase of unknown function (DUF2204) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 337.0
HFD1_k127_2664595_3 Methylpurine-DNA glycosylase (MPG) K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000006957 266.0
HFD1_k127_2664595_5 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000004969 123.0
HFD1_k127_2666629_0 Amidase K01457 - 3.5.1.54 7.566e-289 901.0
HFD1_k127_2666629_1 PFAM FAD linked oxidase domain protein K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 8.637e-257 796.0
HFD1_k127_2666629_2 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 389.0
HFD1_k127_2666629_3 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 368.0
HFD1_k127_2666629_4 GntR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008647 350.0
HFD1_k127_2666629_5 Protein of unknown function (DUF3225) - - - 0.0000000000000000000000000000000000000000000000000000000007078 205.0
HFD1_k127_2688372_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 336.0
HFD1_k127_2688372_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000008698 252.0
HFD1_k127_2688372_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000001572 151.0
HFD1_k127_2688372_3 Zinc-binding dehydrogenase - - - 0.0000000000000000000000015 106.0
HFD1_k127_2690690_0 40-residue YVTN family beta-propeller repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 534.0
HFD1_k127_2690690_1 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 282.0
HFD1_k127_2690690_2 Polysaccharide deacetylase - - - 0.00000000000000002249 84.0
HFD1_k127_2697077_0 amp-dependent synthetase and ligase - - - 9.836e-237 746.0
HFD1_k127_2705762_0 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 5.276e-266 826.0
HFD1_k127_2705762_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006743 395.0
HFD1_k127_2705762_2 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 344.0
HFD1_k127_2705762_3 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000004596 181.0
HFD1_k127_2705762_4 enoyl-CoA hydratase - - - 0.00000000000000000000000000000002894 130.0
HFD1_k127_2719407_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 527.0
HFD1_k127_2719407_1 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 389.0
HFD1_k127_2719407_2 Copper binding periplasmic protein CusF - - - 0.0000000000000000000000000000004249 125.0
HFD1_k127_2728779_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 539.0
HFD1_k127_2728779_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 408.0
HFD1_k127_2728779_2 Glucose / Sorbosone dehydrogenase K21430 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 410.0
HFD1_k127_2728779_3 - - - - 0.0000000000000000000000000000000000000000000000000000000005345 211.0
HFD1_k127_2728779_4 PFAM heat shock protein DnaJ domain protein - - - 0.0000000000000000000000000000000000000000001282 160.0
HFD1_k127_2749390_0 Preprotein translocase subunit SecA (ATPase, RNA helicase) K03070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006509 486.0
HFD1_k127_2749390_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000685 186.0
HFD1_k127_2751933_0 PFAM aminotransferase, class I and II K14260 - 2.6.1.2,2.6.1.66 4.894e-240 746.0
HFD1_k127_2751933_1 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 309.0
HFD1_k127_2751933_2 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000000000000000001987 156.0
HFD1_k127_2751933_3 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000007761 78.0
HFD1_k127_2755697_0 Belongs to the UbiD family K03182 - 4.1.1.98 3.443e-306 943.0
HFD1_k127_2755697_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 3.896e-265 817.0
HFD1_k127_2755697_2 lytic transglycosylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 377.0
HFD1_k127_2755697_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001246 277.0
HFD1_k127_2755697_4 Phosphopantetheine attachment site - - - 0.000000000000000000000000000000000000000000000000000007858 196.0
HFD1_k127_2759388_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 1.255e-214 672.0
HFD1_k127_2759388_1 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 558.0
HFD1_k127_2759388_2 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000007652 241.0
HFD1_k127_2759388_3 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000002908 209.0
HFD1_k127_2767707_0 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006104 500.0
HFD1_k127_2767707_1 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 406.0
HFD1_k127_2767707_2 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005991 402.0
HFD1_k127_2767707_3 Glycosyl transferase family 41 - - - 0.00000000000000000000000000000000000000000000000005784 188.0
HFD1_k127_2767707_4 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.0000000000000000000000000000000003509 139.0
HFD1_k127_2772255_0 aminoacyl-histidine dipeptidase K01270 - - 8.972e-237 739.0
HFD1_k127_2772255_1 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 575.0
HFD1_k127_2772255_2 PFAM DTW domain containing protein K05812 - - 0.0000000000000000000000000000000000000000000000000000000000006238 220.0
HFD1_k127_2780373_0 PFAM periplasmic binding protein K02016,K06858 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 343.0
HFD1_k127_2780373_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000001339 225.0
HFD1_k127_2780373_2 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.00000002971 55.0
HFD1_k127_2804540_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 1.464e-240 749.0
HFD1_k127_281212_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 554.0
HFD1_k127_281212_1 prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 520.0
HFD1_k127_281212_2 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000002403 152.0
HFD1_k127_2816263_0 Belongs to the DEAD box helicase family - GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 - 1.886e-214 683.0
HFD1_k127_2816263_1 PFAM AAA ATPase central domain protein K07478 - - 1.932e-205 649.0
HFD1_k127_2816263_2 Type VI secretion system protein DotU K11892 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 392.0
HFD1_k127_2816263_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009178 291.0
HFD1_k127_2816263_4 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001992 252.0
HFD1_k127_2844658_0 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 1.285e-236 737.0
HFD1_k127_2844658_1 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 318.0
HFD1_k127_2844658_2 TIGRFAM Cu(I)-responsive transcriptional regulator K19591 - - 0.000000000000000000000000000000000000000000000000000001422 200.0
HFD1_k127_2844658_3 hemolysin activation secretion protein - - - 0.00000000000000000000000000000002795 139.0
HFD1_k127_2856525_0 transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005362 602.0
HFD1_k127_2856525_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000001056 140.0
HFD1_k127_2857196_0 Two component regulator propeller - - - 8.023e-229 727.0
HFD1_k127_2858090_0 Flavin-binding monooxygenase-like K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 610.0
HFD1_k127_2858090_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 444.0
HFD1_k127_2858090_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005144 380.0
HFD1_k127_2858090_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000937 348.0
HFD1_k127_2858090_4 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 322.0
HFD1_k127_2858090_5 signal peptide protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001345 267.0
HFD1_k127_2858090_6 Alpha beta hydrolase K14731 - 3.1.1.83 0.000000000000000000000000000000000000000000000000000000000000000000002386 245.0
HFD1_k127_2859603_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0 1222.0
HFD1_k127_2859603_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000002501 193.0
HFD1_k127_2859603_2 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000153 125.0
HFD1_k127_2862056_0 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 586.0
HFD1_k127_2862056_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 561.0
HFD1_k127_2916028_0 TIGRFAM phenylacetate-CoA oxygenase reductase, PaaK subunit K02613,K15983 - 1.14.13.142 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008076 550.0
HFD1_k127_2916028_1 fatty acid desaturase K00508 - 1.14.19.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009385 309.0
HFD1_k127_2916028_2 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 295.0
HFD1_k127_2916028_3 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 292.0
HFD1_k127_2935277_0 TIGRFAM type I secretion system ATPase K12541 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 569.0
HFD1_k127_2935277_1 TIGRFAM type I secretion membrane fusion protein, HlyD family K12542 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008242 373.0
HFD1_k127_2946066_0 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 1.08e-259 803.0
HFD1_k127_2946066_1 AFG1-like ATPase K06916 - - 2.68e-204 640.0
HFD1_k127_2946066_2 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 460.0
HFD1_k127_2946066_3 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000004186 188.0
HFD1_k127_2946066_4 Protein of unknown function (DUF465) - - - 0.000000000000000000000000000006214 120.0
HFD1_k127_2959461_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 301.0
HFD1_k127_2959461_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000002664 245.0
HFD1_k127_2959461_2 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000000000001467 191.0
HFD1_k127_2959461_3 cytochrome oxidase maturation protein - - - 0.00000000007741 65.0
HFD1_k127_2959461_4 Protein conserved in bacteria K09926 - - 0.000000001405 61.0
HFD1_k127_2980424_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009784 531.0
HFD1_k127_2980424_1 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002148 266.0
HFD1_k127_2980424_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000002157 153.0
HFD1_k127_3008158_0 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 5.031e-308 945.0
HFD1_k127_3008158_1 Belongs to the thiolase family K00626 - 2.3.1.9 4.861e-215 672.0
HFD1_k127_3008158_2 LysR substrate binding domain K21703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 425.0
HFD1_k127_3008158_3 Condensation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005505 342.0
HFD1_k127_3008158_4 TfoX N-terminal domain - - - 0.000000000000000000000000000000000002832 140.0
HFD1_k127_3009330_0 Polyhydroxyalkanoate depolymerase, intracellular K05973 - 3.1.1.75 1.161e-217 679.0
HFD1_k127_3009330_1 NADH flavin oxidoreductase NADH oxidase K10680 GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006803 520.0
HFD1_k127_3009330_2 Part of a membrane complex involved in electron transport K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 327.0
HFD1_k127_3009330_3 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009224 321.0
HFD1_k127_3009330_4 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004174 278.0
HFD1_k127_3039901_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 507.0
HFD1_k127_3039901_1 Cell wall-associated K13695,K19303 - - 0.0000000000000000000000000000000000000000000000000000000000000005514 222.0
HFD1_k127_3039901_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000001457 74.0
HFD1_k127_3040463_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 596.0
HFD1_k127_3040463_1 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 392.0
HFD1_k127_3040463_2 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 354.0
HFD1_k127_3040463_3 Protein kinase domain K08282 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 358.0
HFD1_k127_3040463_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005748 244.0
HFD1_k127_3040463_5 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000003252 211.0
HFD1_k127_3048580_0 Involved in the TonB-independent uptake of proteins K03641 - - 3.961e-198 627.0
HFD1_k127_3048580_1 TIGRFAM ribonuclease, Rne Rng family K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 469.0
HFD1_k127_3048580_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006173 264.0
HFD1_k127_3048580_3 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000000000001491 194.0
HFD1_k127_3057450_0 haemagglutination activity domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009925 406.0
HFD1_k127_3058778_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 2.582e-219 686.0
HFD1_k127_3058778_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 2.026e-201 629.0
HFD1_k127_3058778_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007933 371.0
HFD1_k127_3064468_0 Belongs to the heme-copper respiratory oxidase family K02298 - 1.10.3.10 0.0 1218.0
HFD1_k127_3064468_1 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 - - 1.969e-253 790.0
HFD1_k127_3064468_2 PFAM ATP-binding region, ATPase domain protein K15011 - 2.7.13.3 1.022e-198 629.0
HFD1_k127_3064468_3 subunit 2 K02297 - 1.10.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 384.0
HFD1_k127_3064468_4 cytochrome o ubiquinol oxidase subunit III K02299 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 349.0
HFD1_k127_3064468_5 PFAM Surfeit locus 1 family protein K14998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 334.0
HFD1_k127_3064468_6 PFAM response regulator receiver K15012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 294.0
HFD1_k127_3064468_7 TIGRFAM Cytochrome o ubiquinol oxidase subunit IV K02300 - - 0.00000000000000000000000000000000000000000000000000000000513 211.0
HFD1_k127_3064468_8 PEP-CTERM motif - - - 0.000000000000000000000005223 105.0
HFD1_k127_307757_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261 - 1.4.1.2,1.4.1.3 2.568e-214 672.0
HFD1_k127_307757_1 His Kinase A (phosphoacceptor) domain K10125 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 569.0
HFD1_k127_307757_2 ABC-type polar amino acid transport system, ATPase component K10004 - - 0.00000000000000000000000000000000000000000000000000000000000001026 216.0
HFD1_k127_309397_0 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 9.823e-298 928.0
HFD1_k127_309397_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 615.0
HFD1_k127_309397_2 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000000000000000000000000005868 209.0
HFD1_k127_309397_3 chemotaxis, protein K03406 - - 0.000000000000000000000000000000000006993 146.0
HFD1_k127_3096635_0 PrkA AAA domain K07180 - - 0.0 1239.0
HFD1_k127_3096635_1 SpoVR like protein K06415 - - 5.009e-306 940.0
HFD1_k127_3096635_2 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 8.195e-301 942.0
HFD1_k127_3096635_3 Belongs to the UPF0229 family K09786 - - 9.769e-248 768.0
HFD1_k127_3105410_0 Rhs element Vgr protein K11904 - - 1.122e-227 730.0
HFD1_k127_3108282_0 L-lysine 6-monooxygenase (NADPH-requiring) K03897,K10531 - 1.14.13.195,1.14.13.196,1.14.13.59 2.993e-196 621.0
HFD1_k127_3108282_1 Siderophore biosynthesis protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009923 406.0
HFD1_k127_3108282_2 PFAM peptidase S45 penicillin amidase K07116 - 3.5.1.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 353.0
HFD1_k127_3118539_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 1.955e-289 897.0
HFD1_k127_3118539_1 short-chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 447.0
HFD1_k127_3118539_2 TIGRFAM 3-oxoacid CoA-transferase, A subunit K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 429.0
HFD1_k127_3118539_3 TIGRFAM 3-oxoacid CoA-transferase, B subunit K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 340.0
HFD1_k127_3118539_4 Thioesterase superfamily protein K07107 - - 0.00000000000000000000000000000000000000000000000002405 183.0
HFD1_k127_3118539_5 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K16872 - 2.3.1.207 0.0000000000000000000000000000000000000000167 154.0
HFD1_k127_3120970_0 Signal transducing histidine kinase, homodimeric domain K02487,K06596 - - 0.0 1018.0
HFD1_k127_3120970_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 460.0
HFD1_k127_3131106_0 Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family K03455 - - 5.659e-251 785.0
HFD1_k127_3131106_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006363 424.0
HFD1_k127_3131106_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 320.0
HFD1_k127_3131106_3 Catalase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 308.0
HFD1_k127_3131106_4 Bacterial regulatory proteins, tetR family K18939 - - 0.000000000000000000000000000000000000000000000000000000000000001077 223.0
HFD1_k127_3131106_5 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.0001172 44.0
HFD1_k127_3132261_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 531.0
HFD1_k127_3132261_1 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 287.0
HFD1_k127_3132261_2 Ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.00000000000000000000000000000000000000000000000000000000000007955 213.0
HFD1_k127_3133948_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 1.516e-223 702.0
HFD1_k127_3133948_1 Cytochrome C assembly protein - - - 0.000000000000000000000000000000002584 132.0
HFD1_k127_3135640_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 3.432e-227 714.0
HFD1_k127_3135640_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 9.985e-224 707.0
HFD1_k127_3135640_2 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000007509 220.0
HFD1_k127_3135640_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000000000002736 141.0
HFD1_k127_3135640_4 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000000009281 95.0
HFD1_k127_3135640_5 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000000006835 83.0
HFD1_k127_3145879_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1084.0
HFD1_k127_3145879_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 481.0
HFD1_k127_3145879_2 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000006667 255.0
HFD1_k127_3145879_3 TIGRFAM TIGR03790 family protein - - - 0.000000000000000000000000000000006084 127.0
HFD1_k127_3148148_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.347e-248 770.0
HFD1_k127_3148148_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 572.0
HFD1_k127_3148148_2 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 450.0
HFD1_k127_3148148_3 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009984 355.0
HFD1_k127_3148148_4 Smr domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 305.0
HFD1_k127_3148148_5 Peptidyl-prolyl cis-trans K03774 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000008292 262.0
HFD1_k127_3148148_6 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009612 256.0
HFD1_k127_3148148_7 SMART Transport-associated and nodulation region - - - 0.000000000001938 68.0
HFD1_k127_3163559_0 COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 500.0
HFD1_k127_317127_0 aminopeptidase N K01256 - 3.4.11.2 6.783e-208 647.0
HFD1_k127_317127_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 593.0
HFD1_k127_317127_2 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000009909 205.0
HFD1_k127_317256_0 glutamine synthetase K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 561.0
HFD1_k127_317256_1 TIGRFAM glutamine synthetase, type I K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008122 396.0
HFD1_k127_317256_2 Histidine kinase K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 314.0
HFD1_k127_317256_3 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000001088 205.0
HFD1_k127_317256_4 - - - - 0.00000000000000000000000000000000000000001866 161.0
HFD1_k127_3187874_0 homolog of phage Mu protein gp47 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007088 626.0
HFD1_k127_3187874_1 COG2211 Na melibiose symporter and related K03292 - - 0.0000000000000000000005388 106.0
HFD1_k127_3187874_2 homolog of phage Mu protein gp47 - - - 0.0000000000000000009435 88.0
HFD1_k127_319743_0 Tryptophan halogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 589.0
HFD1_k127_319743_1 polysaccharide deacetylase K01452 - 3.5.1.41 0.00000000000000000000000000000000000000000000000000002464 193.0
HFD1_k127_319998_0 membrane-associated Zn-dependent proteases 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 527.0
HFD1_k127_319998_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 311.0
HFD1_k127_3217710_0 Pfam Methyltransferase small - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007752 575.0
HFD1_k127_3217710_1 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 427.0
HFD1_k127_3217710_2 Oxidoreductase-like protein, N-terminal - - - 0.0000000000000000000000000000007313 123.0
HFD1_k127_3217710_3 Flagella basal body rod protein - - - 0.000000000000000000008517 95.0
HFD1_k127_3227157_0 PFAM Haemin-degrading family protein K07225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 343.0
HFD1_k127_3227157_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007332 333.0
HFD1_k127_3227157_2 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001935 259.0
HFD1_k127_3227157_3 TonB dependent receptor K16087 - - 0.00000000000000000000000000000000000000000000000000000000000000004209 234.0
HFD1_k127_3227157_4 Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000183 203.0
HFD1_k127_3234880_0 Chain length determinant protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 503.0
HFD1_k127_3234880_1 CobQ/CobB/MinD/ParA nucleotide binding domain K08252,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 386.0
HFD1_k127_3234880_2 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000005223 145.0
HFD1_k127_3234880_3 - - - - 0.0000000000000000000000000871 111.0
HFD1_k127_3255537_0 PFAM regulatory protein LysR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001653 261.0
HFD1_k127_3255537_1 Chlorhexidine efflux transporter - - - 0.0000000000000000000000000000000000000000000000007166 178.0
HFD1_k127_3256799_0 Protein of unknown function (DUF1631) - - - 2.816e-304 951.0
HFD1_k127_3256799_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 519.0
HFD1_k127_3256799_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 395.0
HFD1_k127_326357_0 Methyl-accepting chemotaxis protein K03406 - - 2.308e-228 718.0
HFD1_k127_326357_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 4.728e-200 625.0
HFD1_k127_326357_2 UTRA K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 405.0
HFD1_k127_326357_3 Succinate dehydrogenase cytochrome b556 subunit K00241 - - 0.0000000000000000000001058 98.0
HFD1_k127_326357_4 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 0.0000000007944 60.0
HFD1_k127_3266172_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 4.802e-265 830.0
HFD1_k127_3266172_1 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 521.0
HFD1_k127_3272140_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 383.0
HFD1_k127_3272140_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 357.0
HFD1_k127_3272140_2 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 315.0
HFD1_k127_3272140_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000001519 204.0
HFD1_k127_3273786_0 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 2.115e-277 856.0
HFD1_k127_3273786_1 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008116 560.0
HFD1_k127_3273786_2 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005881 490.0
HFD1_k127_3273786_3 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 463.0
HFD1_k127_3273786_4 Circularly permuted ATP-grasp type 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 308.0
HFD1_k127_3273786_5 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000000000000000006228 176.0
HFD1_k127_3273786_6 Atp-dependent helicase K03578 - 3.6.4.13 0.0001919 44.0
HFD1_k127_3275950_0 beta-lactamase K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 362.0
HFD1_k127_3275950_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000824 316.0
HFD1_k127_3275950_2 Domain of unknown function (DUF4124) - - - 0.000000000000000002988 90.0
HFD1_k127_3289757_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 514.0
HFD1_k127_3289757_1 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000001869 268.0
HFD1_k127_3289757_2 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000001238 216.0
HFD1_k127_3289757_3 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000000000000000000000000000000000008223 212.0
HFD1_k127_3289757_4 PFAM Membrane protein of K08972 - - 0.00000000000000000000000000000000000000000004296 163.0
HFD1_k127_3289757_5 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000000000000000000000001913 168.0
HFD1_k127_3294067_0 ABC transporter, transmembrane region K06147 - - 0.0 1173.0
HFD1_k127_3294067_1 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.0 1098.0
HFD1_k127_3294067_2 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.0 1039.0
HFD1_k127_3294067_3 Domain of unknown function (DUF1854) - - - 0.0000000000000000000000000000000000000000000000000000001975 203.0
HFD1_k127_330271_1 Double sensory domain of two-component sensor kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 444.0
HFD1_k127_330271_2 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007746 357.0
HFD1_k127_3304444_0 His Kinase A (phosphoacceptor) domain - - - 0.0 1726.0
HFD1_k127_3304444_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 535.0
HFD1_k127_3304444_2 Flagellar Assembly Protein A K09749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 319.0
HFD1_k127_3304444_3 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.000000000000000000000000000000000000000000000000001297 186.0
HFD1_k127_3304444_4 HupE / UreJ protein K03192 - - 0.0000000000000000000000000000000000000000000004973 173.0
HFD1_k127_3306006_0 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 291.0
HFD1_k127_3306006_1 - - - - 0.000000000000000000000000000000000000000000000000000000474 201.0
HFD1_k127_3306006_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000003658 113.0
HFD1_k127_3321089_0 Serine hydrolase involved in the detoxification of formaldehyde K01070 - 3.1.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 404.0
HFD1_k127_3321089_1 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008059 330.0
HFD1_k127_3321089_2 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000312 101.0
HFD1_k127_3321409_0 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 521.0
HFD1_k127_3321409_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 429.0
HFD1_k127_3321409_2 diguanylate cyclase K13069,K21085 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009936 277.0
HFD1_k127_3321409_3 Protein of unknown function (DUF1415) K09941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001472 271.0
HFD1_k127_3321409_4 import inner membrane translocase subunit Tim44 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004709 266.0
HFD1_k127_3321409_5 Diguanylate cyclase K21019 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000001049 237.0
HFD1_k127_3321409_6 chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.000000000000000000000000000000000000000000000136 173.0
HFD1_k127_3325779_0 histidine kinase HAMP region domain protein K03406,K03776,K05874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005254 296.0
HFD1_k127_3325779_1 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001652 270.0
HFD1_k127_3326739_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 325.0
HFD1_k127_3326739_1 RNA polymerase sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003867 273.0
HFD1_k127_3326739_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000019 256.0
HFD1_k127_3326739_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001418 246.0
HFD1_k127_3326739_4 Uncharacterized protein conserved in bacteria (DUF2239) K09965 - - 0.00000000000000000000000000000000000000000000000000000000000001183 221.0
HFD1_k127_3326739_5 Glyoxalase bleomycin resistance protein dioxygenase K07032 - - 0.000000000000000000000000000000000000000000000000000000002178 203.0
HFD1_k127_3326739_6 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000007124 182.0
HFD1_k127_3326739_7 the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000008738 162.0
HFD1_k127_3326739_8 YCII-related domain - - - 0.00000000000000000000000000000000000008765 145.0
HFD1_k127_3326739_9 heavy metal transport detoxification protein K07213 - - 0.00001083 51.0
HFD1_k127_3328855_0 chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 347.0
HFD1_k127_3328855_1 Protein of unknown function (DUF1345) - - - 0.000000000000000000000000000000000000000000000000000000000000000000006871 241.0
HFD1_k127_3328855_2 Glucose / Sorbosone dehydrogenase K21430 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000013 230.0
HFD1_k127_3328855_3 - - - - 0.00000000009927 67.0
HFD1_k127_3340408_0 Secretory lipase - - - 0.00000000000000000000000000000000000000000000000000000000000001491 234.0
HFD1_k127_3340408_1 AraC family - - - 0.00000000000000000006819 96.0
HFD1_k127_3352020_0 TIGRFAM outer membrane adhesin like proteiin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 399.0
HFD1_k127_3352020_1 protein secretion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 369.0
HFD1_k127_3352020_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008662 327.0
HFD1_k127_3352020_3 Domain of unknown function (DUF4347) - - - 0.00000000003058 77.0
HFD1_k127_3359308_0 Belongs to the binding-protein-dependent transport system permease family K11961 - - 2.925e-201 647.0
HFD1_k127_3359308_1 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 517.0
HFD1_k127_3359308_2 urea ABC transporter, ATP-binding protein K11962 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009016 415.0
HFD1_k127_3362846_0 Major Facilitator - - - 1.747e-212 668.0
HFD1_k127_3362846_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000003664 176.0
HFD1_k127_3362846_2 Bacterial protein of unknown function (DUF853) K06915 - - 0.00000000000000000000000000000000000000002705 154.0
HFD1_k127_3377095_0 reductase K00059 - 1.1.1.100 6.887e-233 725.0
HFD1_k127_3377095_1 Iron-containing alcohol dehydrogenase K00043,K00217 - 1.1.1.61,1.3.1.32 1.576e-224 701.0
HFD1_k127_3377095_2 CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 551.0
HFD1_k127_3377095_3 Esterase of the alpha-beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 359.0
HFD1_k127_3377095_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001576 267.0
HFD1_k127_3378016_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 2.203e-266 824.0
HFD1_k127_3378016_1 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 395.0
HFD1_k127_3378016_2 Bacterial protein of unknown function (DUF898) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 374.0
HFD1_k127_3378016_3 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.000000000000000000000000002222 112.0
HFD1_k127_3378016_4 Belongs to the glutamate synthase family - - - 0.00000000000000000000000002086 109.0
HFD1_k127_3388262_0 ABC transporter substrate-binding protein PnrA-like K02058,K07335 - - 3.639e-238 740.0
HFD1_k127_3388262_1 membrane protein, terc K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 557.0
HFD1_k127_3388262_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 541.0
HFD1_k127_3388262_3 Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide K01426,K01455 - 3.5.1.4,3.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 520.0
HFD1_k127_3388262_4 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 491.0
HFD1_k127_3388262_5 mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 423.0
HFD1_k127_3388262_6 Transcriptional regulator K03717 - - 0.00000000000000000009419 89.0
HFD1_k127_3391267_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1207.0
HFD1_k127_3393177_0 TonB-dependent receptor K02014,K16089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 533.0
HFD1_k127_3393177_1 Uncharacterized protein conserved in bacteria (DUF2331) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 420.0
HFD1_k127_3393177_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 353.0
HFD1_k127_3393177_3 Phospholipase/Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 337.0
HFD1_k127_3393177_4 Retinal pigment epithelial membrane protein K21822 - 1.13.11.82 0.0000000000000000000000000000000000000000000000000000009918 196.0
HFD1_k127_3396940_0 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002994 242.0
HFD1_k127_3396940_1 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000924 196.0
HFD1_k127_3396940_2 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000000000000000002832 123.0
HFD1_k127_3396940_3 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.000000000000000000001548 100.0
HFD1_k127_3396940_4 exo-alpha-(2->6)-sialidase activity K12373 - 3.2.1.52 0.000001054 62.0
HFD1_k127_3405218_0 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.0 1160.0
HFD1_k127_3405218_1 chemotaxis sensory transducer K03406 - - 2.769e-238 756.0
HFD1_k127_3405218_10 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000005247 168.0
HFD1_k127_3405218_11 CheD chemotactic sensory transduction K03411 - 3.5.1.44 0.000000000000000000000000000000000000006685 152.0
HFD1_k127_3405218_12 Protein of unknown function (DUF3297) - - - 0.0000000000000000000000000000000000004303 140.0
HFD1_k127_3405218_13 Oxidoreductase-like protein, N-terminal - - - 0.0000000000000000000005935 98.0
HFD1_k127_3405218_14 Extracellular repeat protein, HAF family - - - 0.0000000000001743 82.0
HFD1_k127_3405218_2 SdiA-regulated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 411.0
HFD1_k127_3405218_3 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 374.0
HFD1_k127_3405218_4 AraC family transcriptional regulator K13652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 372.0
HFD1_k127_3405218_5 Tryptophanyl-tRNA synthetase K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 337.0
HFD1_k127_3405218_6 Lamin Tail Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001955 261.0
HFD1_k127_3405218_7 Protein of unknown function (DUF3717) K06938 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003653 249.0
HFD1_k127_3405218_8 - - - - 0.000000000000000000000000000000000000000000000000000000000005298 219.0
HFD1_k127_3405218_9 dienelactone hydrolase K21104 - 3.1.1.101 0.0000000000000000000000000000000000000000000000000000000006552 212.0
HFD1_k127_3409442_0 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 426.0
HFD1_k127_3409442_1 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000005907 128.0
HFD1_k127_3418672_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 3.514e-218 688.0
HFD1_k127_3418672_1 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007894 398.0
HFD1_k127_3418672_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 384.0
HFD1_k127_3418672_3 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 322.0
HFD1_k127_3418672_4 tigrfam pep-cterm - - - 0.00000000624 64.0
HFD1_k127_343026_0 Transcriptional regulator K13643 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009263 341.0
HFD1_k127_343026_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006971 335.0
HFD1_k127_343026_2 Low molecular weight phosphotyrosine protein phosphatase K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000001755 216.0
HFD1_k127_343026_3 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000000000000002095 213.0
HFD1_k127_343026_4 TIGRFAM diguanylate cyclase (GGDEF) domain K21019 - 2.7.7.65 0.00000000000000000000000000000000000000000001003 181.0
HFD1_k127_343026_5 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000003885 117.0
HFD1_k127_3446023_0 FtsX-like permease family K02004 - - 0.0 1140.0
HFD1_k127_3446023_1 basic membrane K02058 - - 1.127e-224 699.0
HFD1_k127_3446023_2 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K21053 - 3.5.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 572.0
HFD1_k127_3446023_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 533.0
HFD1_k127_3446023_4 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 531.0
HFD1_k127_3446023_5 Dead deah box helicase domain protein K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 473.0
HFD1_k127_3446023_6 Protein of unknown function (DUF1275) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 312.0
HFD1_k127_3446023_7 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004061 263.0
HFD1_k127_3452872_0 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 2.56e-318 978.0
HFD1_k127_3452872_1 Nitrogenase molybdenum-iron protein, alpha K02586 - 1.18.6.1 1.314e-236 732.0
HFD1_k127_3452872_2 - - - - 0.00000000000000000000004105 103.0
HFD1_k127_3461915_0 Secretory lipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 351.0
HFD1_k127_3461915_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003134 280.0
HFD1_k127_3461915_2 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000000000000000000000000000000000000000003336 173.0
HFD1_k127_3461915_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000006415 165.0
HFD1_k127_3461915_4 Protein of unknown function (DUF2894) - - - 0.00000001023 56.0
HFD1_k127_3463559_0 Condensation domain - - - 4.117e-265 838.0
HFD1_k127_3469405_0 PFAM PepSY-associated TM helix domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000005554 225.0
HFD1_k127_3469405_1 Universal stress protein - - - 0.000000000000000000000000000000000000000000000000000002193 196.0
HFD1_k127_3469405_2 FMN binding - - - 0.000000000000000000000000000000000000000003043 162.0
HFD1_k127_3470084_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008537 344.0
HFD1_k127_3470084_1 PFAM Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001414 296.0
HFD1_k127_3470084_2 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000000000000000002627 180.0
HFD1_k127_3470084_3 Sulfurtransferase - - - 0.0000000000000000000000000005276 114.0
HFD1_k127_3480429_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 4.225e-257 794.0
HFD1_k127_3480429_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 571.0
HFD1_k127_3480429_2 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000000000000000000000002707 237.0
HFD1_k127_3480429_3 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000000000000000000003955 209.0
HFD1_k127_3480429_4 enoyl-CoA hydratase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000007826 194.0
HFD1_k127_3480429_5 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000000000000000000000004205 187.0
HFD1_k127_3480429_6 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.00000000000000000000000000000000000000001972 155.0
HFD1_k127_3481759_0 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 436.0
HFD1_k127_3481759_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000001087 192.0
HFD1_k127_350649_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family - - - 3.845e-250 785.0
HFD1_k127_3514359_0 Belongs to the ClpA ClpB family K03694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 528.0
HFD1_k127_3514359_1 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000000000001283 240.0
HFD1_k127_3522417_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009948 541.0
HFD1_k127_3522417_1 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 452.0
HFD1_k127_3522417_2 Predicted membrane protein (DUF2214) K08983 - - 0.000000000000000000000000000000000000000000000000000000000000000000587 239.0
HFD1_k127_3522417_3 - - - - 0.00000000002238 65.0
HFD1_k127_3526497_0 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 423.0
HFD1_k127_3526497_1 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003053 274.0
HFD1_k127_3526497_2 TIGRFAM phosphate regulon sensor kinase PhoR K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000371 265.0
HFD1_k127_3565798_0 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006685 523.0
HFD1_k127_3565798_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 GO:0003674,GO:0003824,GO:0003952,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0033554,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 461.0
HFD1_k127_3565798_2 Acyl carrier protein - - - 0.0000000000000000000000000000007812 123.0
HFD1_k127_356595_0 PFAM Radical SAM domain protein - - - 4.996e-201 638.0
HFD1_k127_356595_1 Domain of unknown function (DUF4130 K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 564.0
HFD1_k127_356595_2 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 442.0
HFD1_k127_356595_3 Carboxylesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 325.0
HFD1_k127_356595_4 PFAM MaoC domain protein dehydratase - - - 0.000000000000000000000000001016 113.0
HFD1_k127_3574921_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 557.0
HFD1_k127_3574921_1 Acyl-CoA dehydrogenase, C-terminal domain K00249,K07545 - 1.3.8.3,1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 493.0
HFD1_k127_3574921_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 387.0
HFD1_k127_3574921_3 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 331.0
HFD1_k127_3574921_4 Enoyl-CoA hydratase/isomerase K00020,K01692 - 1.1.1.31,4.2.1.17 0.00000000602 57.0
HFD1_k127_3586183_0 urea ABC transporter, ATP-binding protein K11963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 312.0
HFD1_k127_3586183_1 Domain of unknown function (DUF1841) - - - 0.00000000000000000000000000000000000000000000000000000000000000001682 226.0
HFD1_k127_3586183_2 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000002558 218.0
HFD1_k127_3586183_3 - - - - 0.000000000000000000000000000000000000000000000000000000000001025 223.0
HFD1_k127_3586183_4 TIGRFAM outer membrane adhesin like proteiin - - - 0.0000000000000000000000000000003986 128.0
HFD1_k127_3588117_0 Major Facilitator Superfamily - - - 3.705e-230 724.0
HFD1_k127_3588117_1 Fatty acid desaturase K00496 - 1.14.15.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 571.0
HFD1_k127_3588117_10 pathogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000003945 232.0
HFD1_k127_3588117_11 Cache domain - - - 0.0000000000000000000000000000000006068 145.0
HFD1_k127_3588117_12 TIGRFAM Diguanylate cyclase K13069,K21085 - 2.7.7.65 0.00000000000000000000000000002014 134.0
HFD1_k127_3588117_2 Oxidoreductase FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 483.0
HFD1_k127_3588117_3 ABC transporter K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 477.0
HFD1_k127_3588117_4 transport protein CorA K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 467.0
HFD1_k127_3588117_5 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 448.0
HFD1_k127_3588117_6 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 400.0
HFD1_k127_3588117_7 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 376.0
HFD1_k127_3588117_8 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 387.0
HFD1_k127_3588117_9 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 323.0
HFD1_k127_3621712_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0 1066.0
HFD1_k127_3621712_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 7.006e-232 726.0
HFD1_k127_3621712_10 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 402.0
HFD1_k127_3621712_11 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006016 373.0
HFD1_k127_3621712_12 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 373.0
HFD1_k127_3621712_13 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 327.0
HFD1_k127_3621712_14 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004429 308.0
HFD1_k127_3621712_15 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000553 286.0
HFD1_k127_3621712_16 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004201 254.0
HFD1_k127_3621712_17 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000004481 182.0
HFD1_k127_3621712_2 Tfp pilus assembly protein FimV - - - 1.14e-230 728.0
HFD1_k127_3621712_3 Cobalamin synthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 599.0
HFD1_k127_3621712_4 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008499 578.0
HFD1_k127_3621712_5 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 482.0
HFD1_k127_3621712_6 peptidase S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 479.0
HFD1_k127_3621712_7 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 483.0
HFD1_k127_3621712_8 Transporter associated domain K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 467.0
HFD1_k127_3621712_9 D,D-heptose 1,7-bisphosphate phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 398.0
HFD1_k127_3622047_0 fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 465.0
HFD1_k127_3622047_1 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008842 303.0
HFD1_k127_3622047_2 ABC transporter K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005248 244.0
HFD1_k127_3622230_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 1.849e-213 667.0
HFD1_k127_3622230_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000001098 156.0
HFD1_k127_3622230_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000001299 70.0
HFD1_k127_3630147_0 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 1.788e-244 758.0
HFD1_k127_3630147_1 Domain of unknown function (DUF4118) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008123 574.0
HFD1_k127_3630147_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 441.0
HFD1_k127_3630147_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009855 296.0
HFD1_k127_3630147_4 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.00000006228 54.0
HFD1_k127_3647351_0 Tetrahydrodipicolinate N-succinyltransferase middle K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 483.0
HFD1_k127_3647351_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003572 281.0
HFD1_k127_3647351_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000001895 200.0
HFD1_k127_3650773_0 TIGRFAM filamentous haemagglutinin family outer membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 608.0
HFD1_k127_3650773_1 Crp Fnr family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 382.0
HFD1_k127_3650773_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 340.0
HFD1_k127_3650773_3 Domain of unknown function (DUF4398) - - - 0.00000000000000000000000000000000000000000000000000000000000000000005528 243.0
HFD1_k127_3650773_4 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000004067 147.0
HFD1_k127_3702618_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.557e-303 935.0
HFD1_k127_3725995_0 Bacterial extracellular solute-binding protein K02055 - - 7.166e-232 724.0
HFD1_k127_3725995_1 TOBE domain K02052,K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 509.0
HFD1_k127_3727017_0 metal-dependent phosphohydrolase, HD sub domain K03698,K12070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 417.0
HFD1_k127_3727017_1 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002656 241.0
HFD1_k127_3727017_2 zn-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000515 248.0
HFD1_k127_3727017_3 Protein of unknown function (DUF4256) - - - 0.00000000000000000000000000000000002103 135.0
HFD1_k127_372980_0 PFAM FAD linked oxidase domain protein - - - 3.784e-232 729.0
HFD1_k127_372980_1 UbiA prenyltransferase family - - - 4.532e-228 715.0
HFD1_k127_372980_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 544.0
HFD1_k127_372980_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 397.0
HFD1_k127_372980_4 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 390.0
HFD1_k127_372980_5 Short-chain dehydrogenase reductase (SDR) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008297 381.0
HFD1_k127_372980_6 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 331.0
HFD1_k127_372980_7 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000452 245.0
HFD1_k127_372980_8 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000001052 109.0
HFD1_k127_372980_9 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000002923 109.0
HFD1_k127_3734002_0 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000002271 228.0
HFD1_k127_3734002_1 O-Antigen ligase - - - 0.0000131 56.0
HFD1_k127_3741461_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0 1042.0
HFD1_k127_3741461_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 332.0
HFD1_k127_3756020_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 3.425e-202 637.0
HFD1_k127_3756020_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 600.0
HFD1_k127_3756020_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 390.0
HFD1_k127_3756020_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007804 318.0
HFD1_k127_3756020_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001767 231.0
HFD1_k127_3756020_5 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000000000000002262 201.0
HFD1_k127_3802856_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.101e-314 968.0
HFD1_k127_3802856_1 L-serine dehydratase K01752 - 4.3.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 411.0
HFD1_k127_3802856_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 292.0
HFD1_k127_3802856_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000000000000001086 184.0
HFD1_k127_3802856_4 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000000000000000007625 147.0
HFD1_k127_3804768_0 Dehydratase family K01690 - 4.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 576.0
HFD1_k127_3804768_1 2-keto-4-pentenoate hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003367 258.0
HFD1_k127_3804768_2 - - - - 0.000000000000000002371 86.0
HFD1_k127_3804925_0 Major facilitator superfamily MFS_1 - - - 1.269e-264 824.0
HFD1_k127_3804925_1 PFAM DoxX family protein - - - 0.0000000000000000000000000000000000000000000000001162 183.0
HFD1_k127_3804925_2 amidohydrolase - - - 0.000000000000000000000002914 102.0
HFD1_k127_3805226_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 465.0
HFD1_k127_3805226_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 349.0
HFD1_k127_3805226_2 Helicase c2 K10844 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 342.0
HFD1_k127_381316_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 391.0
HFD1_k127_381316_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 291.0
HFD1_k127_3816134_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 1.713e-280 870.0
HFD1_k127_3816134_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 2.774e-197 631.0
HFD1_k127_3816134_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 304.0
HFD1_k127_3816134_3 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006032 275.0
HFD1_k127_3816134_4 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004398 247.0
HFD1_k127_3816134_5 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000000000000000000000000000004718 210.0
HFD1_k127_3816134_6 YdjC-like protein K03478 - 3.5.1.105 0.000000000000001376 79.0
HFD1_k127_3830017_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 6.271e-200 626.0
HFD1_k127_3830017_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000002513 171.0
HFD1_k127_3830017_2 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000000000002921 136.0
HFD1_k127_3830017_3 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.00000000000000000000000000000003681 125.0
HFD1_k127_3834382_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 1.096e-219 686.0
HFD1_k127_3834382_1 Predicted metal-dependent hydrolase K07044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 407.0
HFD1_k127_3834382_2 Proteobacterial lipase chaperone protein - - - 0.000000000000000000003143 103.0
HFD1_k127_3851062_0 pyruvate phosphate dikinase PEP - - - 9.853e-207 663.0
HFD1_k127_3851062_1 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 469.0
HFD1_k127_3851062_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001276 281.0
HFD1_k127_3851062_3 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000007904 248.0
HFD1_k127_3851062_4 Acyl-ACP thioesterase - - - 0.000000000000000000000000000000000000000000000000000000000004958 212.0
HFD1_k127_3864180_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 5.597e-246 763.0
HFD1_k127_3864180_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 2.05e-196 622.0
HFD1_k127_3864180_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 330.0
HFD1_k127_3864180_3 reductase K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.00000000000000000000000000000000000000000005769 160.0
HFD1_k127_3864180_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000000001089 145.0
HFD1_k127_3864180_5 PFAM Anti sigma-E protein RseA K03597 - - 0.0000000000000000000099 102.0
HFD1_k127_3874774_0 BON domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001786 259.0
HFD1_k127_3874774_1 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000002973 254.0
HFD1_k127_3874774_2 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000000000000000000000000000000000001036 208.0
HFD1_k127_3874774_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000005377 202.0
HFD1_k127_3874774_4 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0008442,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000001834 156.0
HFD1_k127_3881016_0 argininosuccinate lyase K01755 - 4.3.2.1 4.964e-255 792.0
HFD1_k127_3881016_1 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000007381 152.0
HFD1_k127_3881016_2 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000001705 108.0
HFD1_k127_3881016_3 Hemerythrin HHE cation binding domain - - - 0.00000000502 59.0
HFD1_k127_3912560_0 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 420.0
HFD1_k127_3912560_1 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005561 252.0
HFD1_k127_3912560_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000007439 127.0
HFD1_k127_392417_0 Histidine kinase - - - 4.774e-229 728.0
HFD1_k127_392417_1 conserved repeat domain protein - - - 0.000000000000000000000000000000002908 144.0
HFD1_k127_392417_2 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000001387 89.0
HFD1_k127_3946810_0 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 497.0
HFD1_k127_3946810_1 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 384.0
HFD1_k127_3946810_2 Protein of unknown function (DUF3833) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001258 280.0
HFD1_k127_3946810_3 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000007716 154.0
HFD1_k127_3952004_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 0.0 1050.0
HFD1_k127_3952004_1 TIGRFAM methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 5.294e-257 799.0
HFD1_k127_3952004_2 Glutamine amido-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004958 272.0
HFD1_k127_3952004_3 Protein of unknown function (DUF2834) - - - 0.0000000000000000000000000000000002083 136.0
HFD1_k127_3963537_0 homoserine dehydrogenase K00003 - 1.1.1.3 5.946e-219 682.0
HFD1_k127_3963537_1 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008387 443.0
HFD1_k127_3991222_0 NADH dehydrogenase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000004519 246.0
HFD1_k127_3991222_1 - - - - 0.00000000000000000000000000000000000000000000000000002341 206.0
HFD1_k127_3999495_0 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 522.0
HFD1_k127_3999495_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 440.0
HFD1_k127_3999495_2 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000002501 102.0
HFD1_k127_3999604_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 394.0
HFD1_k127_3999604_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 338.0
HFD1_k127_3999604_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000003619 229.0
HFD1_k127_3999604_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000493 224.0
HFD1_k127_3999604_4 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000000000000000001034 141.0
HFD1_k127_3999604_5 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.000004629 49.0
HFD1_k127_4022297_0 Sugar (and other) transporter - - - 1.327e-198 627.0
HFD1_k127_4022297_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02297 - 1.10.3.10 0.00000000000000000000000000000001035 129.0
HFD1_k127_4025739_0 FtsX-like permease family K02004 - - 1.034e-311 971.0
HFD1_k127_4025739_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 4.275e-197 630.0
HFD1_k127_4025739_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 548.0
HFD1_k127_4025739_3 HlyD family secretion protein K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007141 394.0
HFD1_k127_4025739_4 PFAM Short-chain dehydrogenase reductase SDR K00023 - 1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 377.0
HFD1_k127_4025739_5 PFAM CHAD domain containing protein K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002376 267.0
HFD1_k127_4025739_6 - - - - 0.00000000000000000000000000000001475 130.0
HFD1_k127_4025739_7 AAA domain K07028 - - 0.000000000000000009525 85.0
HFD1_k127_4025739_8 PFAM zinc finger, DksA TraR C4-type - - - 0.00000000000003115 77.0
HFD1_k127_4028720_0 Peptidase family M41 K03798 - - 0.0 1158.0
HFD1_k127_4028720_1 Uncharacterized protein conserved in bacteria (DUF2059) K09924 - - 0.00000000001881 66.0
HFD1_k127_4050339_0 ABC transporter K15738 - - 1.659e-239 746.0
HFD1_k127_4058615_0 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 449.0
HFD1_k127_4058615_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 315.0
HFD1_k127_4058615_2 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 293.0
HFD1_k127_4064212_0 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 360.0
HFD1_k127_4064212_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000001388 232.0
HFD1_k127_4064212_2 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000003579 232.0
HFD1_k127_4064212_3 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000005549 192.0
HFD1_k127_4077547_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 1.802e-243 758.0
HFD1_k127_4077547_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 473.0
HFD1_k127_4077547_2 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 420.0
HFD1_k127_4077547_3 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 362.0
HFD1_k127_4077547_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 316.0
HFD1_k127_4100534_0 PFAM sigma-54 factor interaction domain-containing protein K02584,K12266 - - 1.923e-207 656.0
HFD1_k127_4100534_1 EcsC protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000192 275.0
HFD1_k127_4100534_2 LysR family - - - 0.00000000000000000002029 92.0
HFD1_k127_4100534_3 Protein of unknown function (DUF2845) - - - 0.00000000001742 70.0
HFD1_k127_4100534_4 EcsC protein family - - - 0.0000006047 52.0
HFD1_k127_4104613_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 410.0
HFD1_k127_4104613_1 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009967 254.0
HFD1_k127_4104613_2 Required for insertion of 4Fe-4S clusters K15724 - - 0.00000000000000000000000000000000000000000000000000000000000003356 215.0
HFD1_k127_4104613_3 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000000000000000001592 198.0
HFD1_k127_412288_0 Flavin-binding monooxygenase-like K03379,K18371,K21730 - 1.14.13.160,1.14.13.22,1.14.13.226 8.458e-312 959.0
HFD1_k127_412288_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008366 329.0
HFD1_k127_412288_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002298 247.0
HFD1_k127_412288_3 Carboxylesterase family K01066 - - 0.0000000000000000000000000000000000000000000000000000000005569 222.0
HFD1_k127_4128335_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1633.0
HFD1_k127_4128335_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 567.0
HFD1_k127_4128335_2 Asparaginase K01424,K05597 - 3.5.1.1,3.5.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 521.0
HFD1_k127_4128335_3 Bacterial periplasmic substrate-binding proteins K10001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 425.0
HFD1_k127_4128335_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006898 398.0
HFD1_k127_4128335_5 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 382.0
HFD1_k127_4128335_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 291.0
HFD1_k127_4128335_7 PFAM porin Gram-negative type K03285 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000004916 151.0
HFD1_k127_4135494_0 NADH flavin oxidoreductase NADH oxidase - - - 1.964e-224 703.0
HFD1_k127_4135494_1 SWI complex, BAF60b domains - - - 0.000000000000000000000000000000000000000000000007939 173.0
HFD1_k127_4135494_2 helicase activity K08282 - 2.7.11.1 0.000000000000000000000000000000000000647 141.0
HFD1_k127_4135494_3 PFAM PepSY-associated TM helix domain protein K09939 - - 0.0000000000000000000000000000003512 128.0
HFD1_k127_4137815_0 haemagglutination activity domain - - - 0.0000000000000000000000000000000000000000000000000000007334 213.0
HFD1_k127_4149670_0 FAD dependent oxidoreductase K00111 - 1.1.5.3 2.709e-204 649.0
HFD1_k127_4149670_1 Transcriptional regulator K02444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 398.0
HFD1_k127_4149670_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000001935 222.0
HFD1_k127_4153535_0 Tetratricopeptide repeat - - - 2.875e-236 741.0
HFD1_k127_4153535_1 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 526.0
HFD1_k127_4153535_2 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 480.0
HFD1_k127_4153535_3 binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 416.0
HFD1_k127_4153535_4 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000003156 183.0
HFD1_k127_4155007_0 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 516.0
HFD1_k127_4155007_1 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 486.0
HFD1_k127_4155007_2 Transcriptional regulator, LysR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007028 358.0
HFD1_k127_4155007_3 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 312.0
HFD1_k127_4155007_4 Transcription elongation factor, GreA/GreB, C-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 288.0
HFD1_k127_4155007_5 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001121 252.0
HFD1_k127_4155007_6 Domain of unknown function (DUF1857) - - - 0.000000000000000000000000000000000000002461 152.0
HFD1_k127_4159532_0 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002908 265.0
HFD1_k127_4159532_1 CRS1_YhbY K07574 - - 0.000000000000000000000000000000000000000000000000000000000000000001203 230.0
HFD1_k127_4159532_2 Domain of unknown function (DUF4149) - - - 0.000000000000000000000000000006856 123.0
HFD1_k127_4159532_3 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000005654 72.0
HFD1_k127_4160075_0 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 464.0
HFD1_k127_4160075_1 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 298.0
HFD1_k127_4163225_0 N-terminal domain of oxidoreductase K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 602.0
HFD1_k127_4163225_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 430.0
HFD1_k127_4163225_2 KR domain K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 335.0
HFD1_k127_4163225_3 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000305 222.0
HFD1_k127_417884_0 Protein of unknown function (DUF3034) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 403.0
HFD1_k127_417884_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K13888 - - 0.00000000000000000000000002937 111.0
HFD1_k127_4181971_0 Condensation domain - - - 9.414e-221 699.0
HFD1_k127_4189039_0 ABC transporter transmembrane region K18889 - - 6.114e-251 786.0
HFD1_k127_4189039_1 AMP-binding enzyme C-terminal domain K18661 - - 8.765e-250 779.0
HFD1_k127_4189039_2 ABC transporter transmembrane region K18890 - - 1.27e-227 720.0
HFD1_k127_4189039_3 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 1.205e-218 707.0
HFD1_k127_4189039_4 Class II aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 451.0
HFD1_k127_4189039_5 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 389.0
HFD1_k127_4189039_6 - - - - 0.0000000000000000000000000000000000000000000001028 177.0
HFD1_k127_4189039_7 DNA-binding protein VF530 - - - 0.00000000000000000000000000001654 119.0
HFD1_k127_4191134_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 1.018e-206 649.0
HFD1_k127_4191134_1 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 392.0
HFD1_k127_4191134_2 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000001205 186.0
HFD1_k127_4191134_3 - - - - 0.0000000000000000000000000000000002082 133.0
HFD1_k127_4202193_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009784 475.0
HFD1_k127_4202193_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003247 277.0
HFD1_k127_4202193_2 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000001796 148.0
HFD1_k127_42059_0 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 576.0
HFD1_k127_42059_1 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 306.0
HFD1_k127_42059_2 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002795 263.0
HFD1_k127_42059_3 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.00000000000000000000002731 101.0
HFD1_k127_4217686_0 Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate K11103 - - 1.523e-230 719.0
HFD1_k127_4217686_1 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009397 556.0
HFD1_k127_4217686_2 Bile acid sodium symporter K14347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008617 459.0
HFD1_k127_4217686_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 351.0
HFD1_k127_4217686_4 3'-5' exonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004281 260.0
HFD1_k127_4217686_5 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000001483 160.0
HFD1_k127_4218824_0 type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 347.0
HFD1_k127_4218824_1 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003492 245.0
HFD1_k127_4218824_2 Type II secretion system protein G K02456 - - 0.00000000000000000000000000000000000000000000000000002357 197.0
HFD1_k127_4218824_3 Type II secretory pathway, pseudopilin - - - 0.000000000000000000000000000000000000000002823 162.0
HFD1_k127_4218824_4 helix_turn_helix, Lux Regulon - - - 0.00000000000000000001018 97.0
HFD1_k127_4220402_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 357.0
HFD1_k127_4220402_1 - - - - 0.0000000000000000000000000000000000001933 147.0
HFD1_k127_4235373_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 8.701e-216 671.0
HFD1_k127_4235373_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000002822 169.0
HFD1_k127_4235373_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000001315 121.0
HFD1_k127_4236973_0 TonB-dependent Receptor Plug Domain K02014 - - 4.692e-194 626.0
HFD1_k127_4236973_1 Ferredoxin--NADP reductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 452.0
HFD1_k127_4236973_2 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000000000002176 218.0
HFD1_k127_4236973_3 Tetrapyrrole (Corrin/Porphyrin) Methylases K02303 - 2.1.1.107 0.00000000000000000000000000000000000000000000002515 174.0
HFD1_k127_4239319_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 332.0
HFD1_k127_4239319_1 Domain of unknown function (DUF4154) - - - 0.00000000000000000000000000003564 128.0
HFD1_k127_4239319_2 TonB dependent receptor K02014,K16089 - - 0.00000006821 57.0
HFD1_k127_426160_0 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 1.248e-243 760.0
HFD1_k127_426160_1 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 394.0
HFD1_k127_4275692_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 5.502e-273 850.0
HFD1_k127_4275692_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 3.478e-242 752.0
HFD1_k127_4275692_2 Predicted metal-dependent hydrolase K07044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 382.0
HFD1_k127_4275692_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001263 270.0
HFD1_k127_4275692_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003988 239.0
HFD1_k127_4275692_5 - - - - 0.0000000000000000009851 94.0
HFD1_k127_4281615_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 3.505e-312 965.0
HFD1_k127_4281615_1 Flavin-binding monooxygenase-like K07222 - - 1.601e-273 847.0
HFD1_k127_4281615_2 Alpha beta hydrolase K14731 - 3.1.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 518.0
HFD1_k127_4281615_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 349.0
HFD1_k127_4281615_4 Belongs to the UPF0176 family K07146 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 375.0
HFD1_k127_4281615_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000005533 64.0
HFD1_k127_4284791_0 Taurine catabolism dioxygenase TauD TfdA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 533.0
HFD1_k127_4284791_1 Pfam Thioesterase K01071 - 3.1.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 339.0
HFD1_k127_4284791_2 PepSY-associated TM region - - - 0.0000000000000000000000000000000000000000000000147 174.0
HFD1_k127_4284791_3 Sigma-70, region 4 type 2 K03088 - - 0.000000000000000000000000000000000000000007529 159.0
HFD1_k127_4284791_4 PFAM MbtH domain protein K05375 - - 0.0000000000000000000000000000000000000001358 150.0
HFD1_k127_4284791_5 amp-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000002366 143.0
HFD1_k127_4284791_6 iron ion homeostasis K07165 - - 0.000000000001843 68.0
HFD1_k127_428549_0 PFAM Ethanolamine ammonia lyase large subunit K03735 - 4.3.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 376.0
HFD1_k127_428549_1 PFAM sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 352.0
HFD1_k127_428549_2 PFAM glycosyl transferase, family 51 - - - 0.00000000000000000000000000000000002565 137.0
HFD1_k127_4290876_0 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 576.0
HFD1_k127_4290876_1 histone deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 533.0
HFD1_k127_4290876_2 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008874 528.0
HFD1_k127_4293660_0 glutamine synthetase K01915 - 6.3.1.2 3.278e-277 854.0
HFD1_k127_4293660_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K12256 - 2.6.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 324.0
HFD1_k127_4293660_2 Peptidase C26 K07010 - - 0.00000000000000000000000000000002584 128.0
HFD1_k127_4293776_0 type VI secretion protein K11891 - - 0.0 1658.0
HFD1_k127_4293776_1 beta-ketoacyl-acyl-carrier-protein synthase II activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 394.0
HFD1_k127_4293776_2 D-alanyl-D-alanine carboxypeptidase K17733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005811 274.0
HFD1_k127_4293776_3 PAAR motif - - - 0.0000000000000000000000000000000000000000003752 161.0
HFD1_k127_4304166_0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 1.624e-248 776.0
HFD1_k127_4304166_1 TIGRFAM type VI secretion lipoprotein, VC_A0113 family K11906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000912 249.0
HFD1_k127_4321121_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1359.0
HFD1_k127_4321121_1 RNA pseudouridylate synthase K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000005192 215.0
HFD1_k127_4326848_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1322.0
HFD1_k127_4326848_1 Glycine cleavage system T protein K00605 - 2.1.2.10 1.582e-205 644.0
HFD1_k127_4326848_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 519.0
HFD1_k127_4326848_3 TRAP C4-dicarboxylate transport system permease DctM subunit K11690,K21393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 307.0
HFD1_k127_4326848_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000000000000000000000005462 233.0
HFD1_k127_4356075_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 588.0
HFD1_k127_4356075_1 PFAM 20S proteasome, A and B subunits K07395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 478.0
HFD1_k127_4356075_2 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000003029 158.0
HFD1_k127_4357966_0 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 439.0
HFD1_k127_4357966_1 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 362.0
HFD1_k127_4370720_0 malonyl CoA-acyl carrier protein transacylase K00645,K15355 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 512.0
HFD1_k127_4370720_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 329.0
HFD1_k127_4370720_2 reductase K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.00000000000000000000006988 100.0
HFD1_k127_4377835_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.861e-271 839.0
HFD1_k127_4377835_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000004973 160.0
HFD1_k127_4378110_0 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 446.0
HFD1_k127_4378110_1 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 432.0
HFD1_k127_4378110_2 ABC transporter substrate binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 375.0
HFD1_k127_4378110_3 acetolactate synthase K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000001128 266.0
HFD1_k127_4382553_0 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 524.0
HFD1_k127_4382553_1 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002185 280.0
HFD1_k127_4397196_0 urea carboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 553.0
HFD1_k127_4397196_1 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 543.0
HFD1_k127_4397196_2 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 473.0
HFD1_k127_4397196_3 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009385 269.0
HFD1_k127_4409514_0 Anti-sigma-K factor rskA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006552 251.0
HFD1_k127_4409514_1 Protein of unknown function (DUF3455) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001328 234.0
HFD1_k127_4409514_2 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000006541 233.0
HFD1_k127_4414097_0 Penicillin amidase K07116 - 3.5.1.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 574.0
HFD1_k127_4414097_1 Ferric iron reductase FhuF-like transporter K13255 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006536 268.0
HFD1_k127_4414097_2 ATPases associated with a variety of cellular activities K06159,K06160 - - 0.0001428 50.0
HFD1_k127_4414560_0 Urea ABC transporter, urea binding protein K11959 - - 4.229e-213 662.0
HFD1_k127_4414560_1 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001427 265.0
HFD1_k127_4425007_0 rRNA methyltransferase K03437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009724 399.0
HFD1_k127_4425007_1 AsmA family K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006671 400.0
HFD1_k127_4425007_2 Belongs to the BI1 family K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 329.0
HFD1_k127_4425007_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000007591 152.0
HFD1_k127_4461141_0 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 321.0
HFD1_k127_4461141_1 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008451 278.0
HFD1_k127_4461141_2 Pfam SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000007939 242.0
HFD1_k127_4461141_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.000000000000000000707 86.0
HFD1_k127_4461141_4 - - - - 0.00000000000000003305 87.0
HFD1_k127_4472481_0 fad dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 597.0
HFD1_k127_4472481_1 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009397 511.0
HFD1_k127_4472481_2 pteridine-dependent deoxygenase - - - 0.0000000000000000000000000000000000003016 150.0
HFD1_k127_4475718_0 Strictosidine synthase K10440 - - 6.811e-227 704.0
HFD1_k127_4475718_1 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 586.0
HFD1_k127_4475718_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 469.0
HFD1_k127_4475718_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 397.0
HFD1_k127_4506377_0 Trypsin K04691,K04772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 569.0
HFD1_k127_4506377_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008507 538.0
HFD1_k127_4506377_10 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000000000001312 241.0
HFD1_k127_4506377_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000000000000000000000000000000000000000000000005546 194.0
HFD1_k127_4506377_12 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.000000000000000000000000000000000000000000000000004336 183.0
HFD1_k127_4506377_13 Protein of unknown function (DUF1631) - - - 0.000000000000000000000000000000000000004335 152.0
HFD1_k127_4506377_14 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000000000001894 115.0
HFD1_k127_4506377_15 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000007178 51.0
HFD1_k127_4506377_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 494.0
HFD1_k127_4506377_3 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009466 497.0
HFD1_k127_4506377_4 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 472.0
HFD1_k127_4506377_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 407.0
HFD1_k127_4506377_6 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008073 389.0
HFD1_k127_4506377_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 391.0
HFD1_k127_4506377_8 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 390.0
HFD1_k127_4506377_9 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000563 263.0
HFD1_k127_4513660_0 fad dependent oxidoreductase K07137 - - 6.834e-316 972.0
HFD1_k127_4513660_1 Participates in both transcription termination and antitermination K02600 - - 9.167e-288 887.0
HFD1_k127_4513660_2 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 3.963e-230 724.0
HFD1_k127_4513660_3 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 455.0
HFD1_k127_4513660_4 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001054 255.0
HFD1_k127_4513660_5 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000001477 216.0
HFD1_k127_4513660_6 binding-protein-dependent transport systems inner membrane component K13895 - - 0.0000000000000000000000000000000000000001863 150.0
HFD1_k127_451473_0 Aminotransferase K14267 - 2.6.1.17 3.199e-234 728.0
HFD1_k127_451473_1 twitching motility protein K02670 - - 3.725e-210 659.0
HFD1_k127_451473_2 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009102 529.0
HFD1_k127_451473_3 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000007133 207.0
HFD1_k127_451473_4 GGDEF domain K21019 - 2.7.7.65 0.0000000000000000007872 89.0
HFD1_k127_4514808_0 Thioredoxin K05838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 428.0
HFD1_k127_4514808_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005314 281.0
HFD1_k127_4514808_2 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000007854 181.0
HFD1_k127_4522993_0 Bacterial protein of unknown function (DUF839) K07093 - - 7.056e-270 846.0
HFD1_k127_4522993_1 general secretion pathway protein K02456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006628 271.0
HFD1_k127_4522993_2 type II secretion system protein - - - 0.000001371 51.0
HFD1_k127_4544451_0 PFAM ATP-binding region, ATPase domain protein K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 503.0
HFD1_k127_4544451_1 Two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 353.0
HFD1_k127_4544451_2 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000006721 209.0
HFD1_k127_4553799_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 509.0
HFD1_k127_4553799_1 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 417.0
HFD1_k127_4553799_2 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000002477 213.0
HFD1_k127_4560992_0 translation initiation factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009686 437.0
HFD1_k127_4560992_1 photoreceptor activity - - - 0.000000000000000000000000002673 113.0
HFD1_k127_4573626_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03387 - - 1.657e-256 794.0
HFD1_k127_4573626_1 LysR substrate binding domain K18900 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 355.0
HFD1_k127_4573626_2 alpha/beta hydrolase fold K01066 - - 0.00001053 49.0
HFD1_k127_4589482_0 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 599.0
HFD1_k127_4589482_1 endonuclease exonuclease phosphatase K07004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 369.0
HFD1_k127_4589482_2 - - - - 0.000000000000000000000000000000009011 140.0
HFD1_k127_4593288_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007819 342.0
HFD1_k127_4595952_0 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 441.0
HFD1_k127_4595952_1 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000004062 188.0
HFD1_k127_4607894_0 Phosphoribulokinase K00855 - 2.7.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 372.0
HFD1_k127_4607894_1 Alkyl hydroperoxide reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000103 245.0
HFD1_k127_4607894_2 subfamily IA, variant 1 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000002279 236.0
HFD1_k127_4607894_3 Domain of unknown function (DUF427) - - - 0.0000000000000000000000000000000000000000006535 158.0
HFD1_k127_4614250_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 2.605e-196 619.0
HFD1_k127_4614250_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 8.654e-194 610.0
HFD1_k127_4614250_2 Thiamine monophosphate synthase K00941,K14153 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 539.0
HFD1_k127_4614250_3 Domain of unknown function (DUF1857) - - - 0.00000000000000000000000000000000000000000000000000000000000000001714 226.0
HFD1_k127_4614250_4 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000008392 211.0
HFD1_k127_4614250_5 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000003276 108.0
HFD1_k127_4631571_0 Linear gramicidin synthase subunit - - - 5.616e-240 754.0
HFD1_k127_4631571_1 Condensation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006418 624.0
HFD1_k127_4639591_0 Mitochondrial degradasome RNA helicase subunit C terminal K17675 - 3.6.4.13 0.0 1069.0
HFD1_k127_4639591_1 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 1.286e-228 719.0
HFD1_k127_4639591_2 helicase superfamily c-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 561.0
HFD1_k127_4639591_3 alpha/beta hydrolase fold K01046 - 3.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 498.0
HFD1_k127_4639591_4 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 425.0
HFD1_k127_4639591_5 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 392.0
HFD1_k127_4639591_6 Proteobacterial lipase chaperone protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 384.0
HFD1_k127_4639591_7 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006527 322.0
HFD1_k127_4639591_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 301.0
HFD1_k127_4662677_0 PFAM glucose-methanol-choline oxidoreductase K00108 - 1.1.99.1 2.456e-266 827.0
HFD1_k127_4662677_1 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 355.0
HFD1_k127_4683333_0 - - - - 3.51e-270 842.0
HFD1_k127_4683333_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 590.0
HFD1_k127_4683333_2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000004578 244.0
HFD1_k127_4683333_3 Methyltransferase - - - 0.0000000000000000000000001502 114.0
HFD1_k127_4686895_0 TIGRFAM malto-oligosyltrehalose trehalohydrolase K01236 - 3.2.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004509 618.0
HFD1_k127_4686895_1 Belongs to the glycosyl hydrolase 13 family K01200,K01214 - 3.2.1.41,3.2.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000687 366.0
HFD1_k127_4689205_0 non-ribosomal peptide synthetase - - - 5.153e-309 974.0
HFD1_k127_4692332_0 Domain of unknown function (DUF1993) K09983 - - 0.00000000000000000000000000000000000000000000000000000000000000001339 229.0
HFD1_k127_4692332_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000007448 200.0
HFD1_k127_4692332_2 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.00000000000000000000000000000000000000000000871 164.0
HFD1_k127_4692332_3 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000000000000000000000000000000001812 153.0
HFD1_k127_4692332_4 Diguanylate cyclase - - - 0.00000000000000004445 83.0
HFD1_k127_4704848_0 transport system permease component K13895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 502.0
HFD1_k127_4704848_1 PFAM binding-protein-dependent transport systems inner membrane component K13894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 344.0
HFD1_k127_4710088_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 397.0
HFD1_k127_4710088_1 Catalase - - - 0.00000000000000000000000000000000000000000000000000000000003258 207.0
HFD1_k127_4713980_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 2.313e-212 665.0
HFD1_k127_4713980_1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000000000000000000000002566 193.0
HFD1_k127_4713980_2 regulatory protein, MerR - - - 0.000000000000000000000000000000000000000000001557 166.0
HFD1_k127_4768923_0 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 355.0
HFD1_k127_4768923_1 Sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 319.0
HFD1_k127_4768923_2 serine dehydratase beta chain K01752 - 4.3.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 300.0
HFD1_k127_4771948_0 Putative modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007104 458.0
HFD1_k127_4771948_1 Putative modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017 449.0
HFD1_k127_4771948_2 Protein of unknown function (DUF3606) - - - 0.0000005593 55.0
HFD1_k127_4783525_0 Biotin carboxylase C-terminal domain K13777 - 6.4.1.5 6.678e-300 933.0
HFD1_k127_4783525_1 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 2.509e-224 698.0
HFD1_k127_4783525_2 beta-keto acid cleavage enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 488.0
HFD1_k127_4783525_3 Enoyl-CoA hydratase/isomerase K13779 - 4.2.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 352.0
HFD1_k127_4783525_4 Carboxyl transferase domain K13778 - 6.4.1.5 0.0000000000000000000000000000000000000000000000000000000000008964 211.0
HFD1_k127_4788291_0 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 459.0
HFD1_k127_4788291_1 YdjC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001477 248.0
HFD1_k127_4788291_2 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001192 241.0
HFD1_k127_4788291_3 PFAM HAMP domain, Methyl-accepting chemotaxis protein (MCP) signaling domain K03406,K03776,K05874 - - 0.000000000000000000000000000000000000002357 158.0
HFD1_k127_4791323_0 serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 0.0 1144.0
HFD1_k127_4791323_1 Involved in chromosome partitioning - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 370.0
HFD1_k127_4791323_2 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 352.0
HFD1_k127_4791323_3 Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer K22105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 311.0
HFD1_k127_4791323_4 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000007068 198.0
HFD1_k127_4791323_5 Beta-lactamase - - - 0.000000000000000000000000000003737 120.0
HFD1_k127_4791835_0 Domain of unknown function (DUF4347) - - - 3.805e-212 678.0
HFD1_k127_4792212_0 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K04090 - 1.2.7.8 0.0 1789.0
HFD1_k127_4792212_1 Carboxyl transferase domain K01969 - 6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 446.0
HFD1_k127_4792212_2 YsiA-like protein, C-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 355.0
HFD1_k127_4794879_0 Acyl-CoA dehydrogenase, middle domain K00252 - 1.3.8.6 1.858e-208 653.0
HFD1_k127_4794879_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000002084 235.0
HFD1_k127_4794879_2 DUF218 domain - - - 0.0000000003836 65.0
HFD1_k127_479579_0 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 526.0
HFD1_k127_479579_1 cell envelope organization K05807,K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 371.0
HFD1_k127_479579_3 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000001948 51.0
HFD1_k127_4813140_0 Dioxygenase - - - 0.0000000000000000000000000000000000000000000000001034 188.0
HFD1_k127_4813140_1 Regulator K02483 - - 0.00000000000000000000000000886 119.0
HFD1_k127_4832919_0 carboxylase K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.4 1.493e-284 891.0
HFD1_k127_4832919_1 PFAM acyl-CoA dehydrogenase domain protein K00253 - 1.3.8.4 3.547e-226 704.0
HFD1_k127_4832919_2 HMGL-like K01640 GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 502.0
HFD1_k127_4832919_3 enoyl-CoA hydratase K13766,K15312 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 362.0
HFD1_k127_4832919_4 Carboxyl transferase domain K01969 - 6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 286.0
HFD1_k127_4840406_0 Type II secretion system K02653 - - 1.397e-226 706.0
HFD1_k127_4840406_1 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 488.0
HFD1_k127_4840406_2 TIGRFAM type IV-A pilus assembly ATPase PilB K02454,K02504,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004389 274.0
HFD1_k127_4851686_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 584.0
HFD1_k127_4851686_1 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 481.0
HFD1_k127_4851959_0 OHCU decarboxylase K02083,K06016 - 3.5.1.6,3.5.1.87,3.5.3.9 4.604e-295 915.0
HFD1_k127_4851959_1 PFAM Polysaccharide deacetylase K01452 - 3.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 569.0
HFD1_k127_4851959_2 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 319.0
HFD1_k127_4851959_3 peptidase dimerisation domain protein - - - 0.0000000000000000000000000000000000000000000000000000738 194.0
HFD1_k127_4851959_4 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.0000000000000000000000000000000000000000000001377 172.0
HFD1_k127_4851959_5 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000006203 130.0
HFD1_k127_4852182_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 1.979e-221 698.0
HFD1_k127_4852182_1 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000008048 242.0
HFD1_k127_486064_0 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 407.0
HFD1_k127_486064_1 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 380.0
HFD1_k127_486064_2 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000004241 183.0
HFD1_k127_486064_3 PAS fold - - - 0.00000000000000000000000000000000000000000000005114 185.0
HFD1_k127_4865261_0 amine dehydrogenase activity - - - 0.0 1018.0
HFD1_k127_4865261_1 diguanylate cyclase - - - 0.00000004533 55.0
HFD1_k127_4875732_0 intradiol ring-cleavage dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003458 252.0
HFD1_k127_4875732_1 histidine kinase HAMP region domain protein K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000003573 237.0
HFD1_k127_4881802_0 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009203 602.0
HFD1_k127_4881802_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000009903 231.0
HFD1_k127_4881802_2 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000002568 144.0
HFD1_k127_4908371_0 Peptidase family C25 - - - 0.0 1233.0
HFD1_k127_4908371_1 Esterase-like activity of phytase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008011 583.0
HFD1_k127_4908371_2 PEP-CTERM motif - - - 0.00000000000000000000000000000000000000000000000000000000000000009104 226.0
HFD1_k127_4908371_3 SNARE associated Golgi protein - - - 0.00000000000000000000000000002665 119.0
HFD1_k127_4912567_0 Oxygenase, catalysing oxidative methylation of damaged DNA K09990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 351.0
HFD1_k127_4912567_1 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247,K13529 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001243 284.0
HFD1_k127_4912567_2 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003908,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006282,GO:0006304,GO:0006305,GO:0006306,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0007275,GO:0007584,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009008,GO:0009314,GO:0009605,GO:0009628,GO:0009636,GO:0009888,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010212,GO:0010243,GO:0010604,GO:0010941,GO:0014070,GO:0016740,GO:0016741,GO:0016765,GO:0019219,GO:0019222,GO:0030154,GO:0030162,GO:0030855,GO:0030879,GO:0031323,GO:0031325,GO:0031667,GO:0031974,GO:0031981,GO:0032259,GO:0032501,GO:0032502,GO:0033273,GO:0033554,GO:0034599,GO:0034641,GO:0035510,GO:0042221,GO:0042493,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043281,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0044728,GO:0045471,GO:0045739,GO:0045935,GO:0046483,GO:0046677,GO:0046872,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051173,GO:0051246,GO:0051336,GO:0051593,GO:0051716,GO:0052547,GO:0052548,GO:0060255,GO:0060429,GO:0060548,GO:0060644,GO:0061180,GO:0065007,GO:0065009,GO:0070013,GO:0070887,GO:0071214,GO:0071310,GO:0071407,GO:0071478,GO:0071479,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097305,GO:0104004,GO:0140097,GO:1901360,GO:1901363,GO:1901698,GO:1901700,GO:2000116,GO:2000779,GO:2000781,GO:2001020,GO:2001022 2.1.1.63 0.00000000000000000000000000000000000000000000000000000002328 203.0
HFD1_k127_4912567_3 Methyltransferase K00567,K10778 - 2.1.1.63 0.00000000000000006375 80.0
HFD1_k127_4920451_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 576.0
HFD1_k127_4922223_0 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009352 274.0
HFD1_k127_4922223_1 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000004947 235.0
HFD1_k127_4922545_0 diguanylate cyclase K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 442.0
HFD1_k127_4922545_1 diguanylate cyclase K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 314.0
HFD1_k127_4922976_0 histidine kinase HAMP region domain protein K03406,K03776,K05874,K05875 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008705 371.0
HFD1_k127_4922976_1 Universal stress protein family - - - 0.0000000000000000000000000000000001062 138.0
HFD1_k127_4922976_2 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000008332 123.0
HFD1_k127_4927905_0 Domain of unknown function (DUF4331) - - - 3.384e-219 692.0
HFD1_k127_4927905_1 NADH flavin oxidoreductase NADH oxidase K10680 GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700 - 4.533e-197 620.0
HFD1_k127_4927905_2 tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 297.0
HFD1_k127_4937419_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 4.15e-217 679.0
HFD1_k127_4937419_1 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 481.0
HFD1_k127_4937419_2 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K01243 - 3.2.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 298.0
HFD1_k127_4937419_3 RESPONSE REGULATOR receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009073 291.0
HFD1_k127_4937419_4 Helix-turn-helix XRE-family like proteins K21498 - - 0.00000000000000000000000000000000000000000000001338 175.0
HFD1_k127_4937419_5 Transcriptional regulator K10914 - - 0.000000000000000000000000000000000000000000004266 174.0
HFD1_k127_4937419_6 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000004586 173.0
HFD1_k127_4937419_7 Membrane - - - 0.00000000000000000000000159 106.0
HFD1_k127_4937419_8 transporter component K07112 - - 0.0000000007831 61.0
HFD1_k127_4944616_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 453.0
HFD1_k127_4944616_1 Belongs to the peptidase S11 family K07262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 449.0
HFD1_k127_4944616_2 TIGRFAM TIGR03790 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 397.0
HFD1_k127_4944616_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 298.0
HFD1_k127_4955675_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 3.985e-203 639.0
HFD1_k127_4955675_1 Polysaccharide biosynthesis C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 397.0
HFD1_k127_4958215_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008878 381.0
HFD1_k127_4958215_1 short-chain K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009605 380.0
HFD1_k127_4958215_2 Dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000000000000000000452 203.0
HFD1_k127_4958215_3 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000001809 208.0
HFD1_k127_4960027_0 Uncharacterized protein conserved in bacteria (DUF2094) K11890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 428.0
HFD1_k127_4960027_1 OmpA family K02557,K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 373.0
HFD1_k127_4960027_2 ImpA, N-terminal, type VI secretion system K11902 - - 0.00000000000000000000000000000001234 128.0
HFD1_k127_4977203_0 STAS-like domain of unknown function (DUF4325) - - - 0.000000000000000000000000000000000000000000000000000000000000000000006442 246.0
HFD1_k127_4977203_1 Cold shock protein K03704 - - 0.000000000000000000000000000001086 123.0
HFD1_k127_4977203_2 Protein of unknown function (DUF1653) - - - 0.0000000000000266 73.0
HFD1_k127_4978867_0 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 373.0
HFD1_k127_4978867_1 Cyd operon protein YbgE (Cyd_oper_YbgE) - - - 0.0000000000000000000000009831 117.0
HFD1_k127_4978867_2 Membrane bound YbgT-like protein K00424 - 1.10.3.14 0.000000000001516 68.0
HFD1_k127_4979032_0 Flavin-binding monooxygenase-like - - - 4.245e-232 731.0
HFD1_k127_4979032_1 MreB/Mbl protein K04046 - - 3.441e-212 666.0
HFD1_k127_4979032_2 COG0642 Signal transduction histidine kinase K11527 - 2.7.13.3 1.465e-195 645.0
HFD1_k127_4979032_3 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 560.0
HFD1_k127_4979032_4 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009136 469.0
HFD1_k127_4979032_5 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000003926 177.0
HFD1_k127_4979032_6 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000007225 152.0
HFD1_k127_4979032_8 - - - - 0.0002491 51.0
HFD1_k127_4987663_0 Domain of unknown function (DUF4347) - - - 0.000000000000000000000000000000000000000000000000009639 206.0
HFD1_k127_4987663_1 Domain of unknown function (DUF4347) - - - 0.0000000000000000000000000000000000000008247 171.0
HFD1_k127_4987663_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000001534 94.0
HFD1_k127_4995209_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1144.0
HFD1_k127_4995209_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006859 577.0
HFD1_k127_4995209_2 transcriptional regulator K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 555.0
HFD1_k127_4995209_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 423.0
HFD1_k127_4995209_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000004257 219.0
HFD1_k127_4995209_5 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000322 166.0
HFD1_k127_500227_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 567.0
HFD1_k127_500227_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005906 382.0
HFD1_k127_500227_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 341.0
HFD1_k127_500227_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000002491 246.0
HFD1_k127_500227_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000004462 169.0
HFD1_k127_502521_0 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 598.0
HFD1_k127_502521_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002752 236.0
HFD1_k127_502521_2 Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02403 - - 0.0009538 45.0
HFD1_k127_502553_0 fatty acid desaturase K00508 - 1.14.19.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 462.0
HFD1_k127_502553_1 fatty acid desaturase K00508 - 1.14.19.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 295.0
HFD1_k127_5072220_0 type II secretion system protein E K02454 - - 3.544e-234 729.0
HFD1_k127_5072220_1 Spermidine synthase K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000003036 252.0
HFD1_k127_5085921_0 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 422.0
HFD1_k127_5085921_1 Acetyl-coenzyme A transporter 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 318.0
HFD1_k127_5085921_2 PFAM YiaAB two helix domain protein - - - 0.0000000000000000000000000000000000000000000000000000000001219 207.0
HFD1_k127_5085921_3 - - - - 0.000000000000000000000000000001172 126.0
HFD1_k127_5085921_4 Uncharacterized protein conserved in bacteria (DUF2145) - - - 0.0000000000000817 73.0
HFD1_k127_5086760_0 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 314.0
HFD1_k127_5086760_1 RDD family - - - 0.0000000000000000000000000000000000000000000000000000000000000002253 224.0
HFD1_k127_5086760_2 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000000000001601 213.0
HFD1_k127_5086760_3 Peptidogalycan biosysnthesis/recognition K09919 - - 0.00000000000000000000000000000000000000000000000000003043 192.0
HFD1_k127_5090729_0 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 2.739e-273 846.0
HFD1_k127_5090729_1 Secretory lipase - - - 1.317e-244 760.0
HFD1_k127_5090729_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008087 600.0
HFD1_k127_5090729_3 aspartyl asparaginyl beta-hydroxylase K12979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 434.0
HFD1_k127_5090729_4 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 370.0
HFD1_k127_5090729_5 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 364.0
HFD1_k127_5090729_6 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 291.0
HFD1_k127_5090729_7 Histidine kinase - - - 0.0000000000000000000000000000000000000000000006395 186.0
HFD1_k127_5090729_8 PFAM response regulator receiver K11443 - - 0.000000000000000000000000000000000000004076 149.0
HFD1_k127_5115991_0 Signal transducing histidine kinase, homodimeric domain K02487,K06596 - - 3.465e-294 918.0
HFD1_k127_512049_0 Helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 458.0
HFD1_k127_512049_1 luxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 374.0
HFD1_k127_512049_2 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000008548 211.0
HFD1_k127_5129392_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009192 429.0
HFD1_k127_5129392_1 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 336.0
HFD1_k127_5129392_2 Protein of unknown function (DUF2818) - - - 0.0000000000000000000000000000000009045 132.0
HFD1_k127_5129392_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000001202 121.0
HFD1_k127_5129392_4 Esterase-like activity of phytase K01126 - 3.1.4.46 0.000003196 50.0
HFD1_k127_5132350_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 471.0
HFD1_k127_5132350_1 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004508 266.0
HFD1_k127_5138395_0 Glycosyl transferase family 21 K03669 - - 0.0 1043.0
HFD1_k127_5138395_1 Periplasmic glucan biosynthesis protein, MdoG K03670 - - 5.83e-267 829.0
HFD1_k127_5138395_2 Protein tyrosine kinase K08282 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 552.0
HFD1_k127_5138395_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004245 257.0
HFD1_k127_5138395_4 Uncharacterized protein conserved in bacteria (DUF2094) K11890 - - 0.000000000000000000000000000000000000003872 158.0
HFD1_k127_5138395_5 Caspase domain - - - 0.00000000000000000003325 104.0
HFD1_k127_5138395_6 filamentous hemagglutinin family N-terminal domain - - - 0.00000000000000001226 99.0
HFD1_k127_5140858_0 PFAM response regulator receiver K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 295.0
HFD1_k127_5140858_1 - - - - 0.0000000000000000000000000000000000000000000005886 173.0
HFD1_k127_5140858_2 Histidine kinase K07638 - 2.7.13.3 0.00000000000000000000000003907 115.0
HFD1_k127_5143599_0 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 490.0
HFD1_k127_5143599_1 AraC-type transcriptional regulator N-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 459.0
HFD1_k127_5143599_2 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008296 294.0
HFD1_k127_5143599_3 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000008046 212.0
HFD1_k127_5145418_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 9.848e-284 878.0
HFD1_k127_5145418_1 mannitol 2-dehydrogenase activity - - - 1.649e-197 635.0
HFD1_k127_5157960_0 Succinate dehydrogenase fumarate reductase, flavoprotein subunit - - - 8.205e-307 949.0
HFD1_k127_5157960_1 UTRA K03710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 312.0
HFD1_k127_5157960_2 4fe-4S ferredoxin - - - 0.000000000000000000000000000000000001895 144.0
HFD1_k127_5158213_0 two-component response regulator K07662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 322.0
HFD1_k127_5158213_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K02484,K07640,K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 313.0
HFD1_k127_5158213_2 RND efflux system, outer membrane lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000002925 217.0
HFD1_k127_5158213_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000007731 194.0
HFD1_k127_5158213_4 PFAM regulatory protein TetR K22105 - - 0.000000000000000000000000000000000000000001024 162.0
HFD1_k127_5158213_5 GMC family oxidoreductase - - - 0.000000000002695 71.0
HFD1_k127_5180888_0 Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations K01241 - 3.2.2.4 3.849e-269 831.0
HFD1_k127_5180888_1 Biopolymer transport protein K03559,K03560 - - 0.000000000000000000000000000000000000000001764 163.0
HFD1_k127_5180888_2 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000004442 96.0
HFD1_k127_5187211_0 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 1.035e-194 611.0
HFD1_k127_5187211_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 532.0
HFD1_k127_5187211_2 Transcriptional regulator K13635 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 510.0
HFD1_k127_5187211_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07789 - - 0.000000000000000000000000000000001494 132.0
HFD1_k127_519520_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 2.26e-215 673.0
HFD1_k127_519520_1 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 441.0
HFD1_k127_5216814_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0 1496.0
HFD1_k127_5216814_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 593.0
HFD1_k127_5216814_2 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 514.0
HFD1_k127_5216814_3 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006518 265.0
HFD1_k127_5216814_4 Lysine methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002253 265.0
HFD1_k127_5216814_5 Lipase (class 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005549 258.0
HFD1_k127_5226522_0 OmpA family - - - 1.514e-221 697.0
HFD1_k127_5226522_1 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004232 276.0
HFD1_k127_5233353_0 ABC transporter K02056 - 3.6.3.17 2.795e-256 797.0
HFD1_k127_5233353_1 Guanine deaminase K01487 - 3.5.4.3 1.48e-227 711.0
HFD1_k127_5233353_2 Transcriptional regulator, LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 608.0
HFD1_k127_5233353_3 Xanthine dehydrogenase small subunit K13481 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 383.0
HFD1_k127_5233353_4 Branched-chain amino acid transport system / permease component - - - 0.0000000003967 63.0
HFD1_k127_5282114_0 - - - - 0.00000000000000000000000000000000000000000002985 165.0
HFD1_k127_5282114_1 SMART Transport-associated and nodulation region K04065 - - 0.0000000000000000005715 91.0
HFD1_k127_5282114_3 Protein of unknown function (DUF1328) - - - 0.000000000000001328 78.0
HFD1_k127_5282114_5 - - - - 0.0000000000005289 74.0
HFD1_k127_5284652_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 541.0
HFD1_k127_5284652_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008699 547.0
HFD1_k127_5284652_2 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 487.0
HFD1_k127_5284652_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008037 427.0
HFD1_k127_5284652_4 NlpB/DapX lipoprotein K07287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009675 424.0
HFD1_k127_5284652_5 The M ring may be actively involved in energy transduction K02409 - - 0.000000000000000000000000000000000000000000000000000000000000006533 221.0
HFD1_k127_5284652_6 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000000000000000000000000000000000000000000000444 171.0
HFD1_k127_5284652_7 - - - - 0.00000000000000000000002936 106.0
HFD1_k127_5284652_8 - - - - 0.000000002106 63.0
HFD1_k127_5286845_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 546.0
HFD1_k127_5286845_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019 GO:0000003,GO:0000166,GO:0001568,GO:0001676,GO:0001944,GO:0003674,GO:0003824,GO:0004888,GO:0004930,GO:0004953,GO:0004954,GO:0004955,GO:0004957,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006636,GO:0006690,GO:0006692,GO:0006693,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007179,GO:0007186,GO:0007275,GO:0007276,GO:0007292,GO:0007565,GO:0007567,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009653,GO:0009719,GO:0009987,GO:0010033,GO:0016053,GO:0016404,GO:0016491,GO:0016614,GO:0016616,GO:0019372,GO:0019752,GO:0019953,GO:0022414,GO:0023052,GO:0030728,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0033559,GO:0035239,GO:0035295,GO:0036094,GO:0038023,GO:0042221,GO:0042759,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0045786,GO:0046394,GO:0046456,GO:0046983,GO:0048037,GO:0048514,GO:0048519,GO:0048523,GO:0048609,GO:0048731,GO:0048844,GO:0048856,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051287,GO:0051704,GO:0051716,GO:0051726,GO:0055114,GO:0060089,GO:0060840,GO:0065007,GO:0070013,GO:0070403,GO:0070493,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071495,GO:0071559,GO:0071560,GO:0071704,GO:0072330,GO:0072358,GO:0072359,GO:0097070,GO:0097159,GO:1901265,GO:1901363,GO:1901568,GO:1901570,GO:1901576,GO:2001300,GO:2001301 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 438.0
HFD1_k127_5286845_2 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 399.0
HFD1_k127_5286845_3 Pirin C-terminal cupin domain K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 304.0
HFD1_k127_5286845_4 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000009879 229.0
HFD1_k127_5286845_5 Domain of unknown function (DUF1924) - - - 0.000000000000000000000000006404 112.0
HFD1_k127_5286845_6 Pirin C-terminal cupin domain K06911 - - 0.00000000000000000000000001199 111.0
HFD1_k127_528821_0 Response regulator receiver K02658 - - 0.0000000000000000000000000000000000003337 144.0
HFD1_k127_528821_1 cheY-homologous receiver domain - - - 0.0000000000000000000000003251 116.0
HFD1_k127_528821_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.000000000000994 79.0
HFD1_k127_528821_3 chemotaxis signal transduction protein K03408 - - 0.00003033 53.0
HFD1_k127_5289182_0 TIGRFAM type I secretion system ATPase K12541 - - 3.493e-270 851.0
HFD1_k127_5289182_1 Glycosyl transferase family 41 - - - 2.263e-196 619.0
HFD1_k127_5289182_2 TIGRFAM type I secretion membrane fusion protein, HlyD family K12542 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 610.0
HFD1_k127_5289182_3 Outer membrane efflux protein K12543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 454.0
HFD1_k127_5289182_4 Outer membrane efflux protein K12543 - - 0.000000000000000000000000000000000000003154 160.0
HFD1_k127_5289182_5 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000001979 153.0
HFD1_k127_5298344_0 Aldehyde dehydrogenase family K00130,K09472,K12254 - 1.2.1.54,1.2.1.8,1.2.1.99 1.108e-240 752.0
HFD1_k127_5298344_1 ATPase MipZ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 335.0
HFD1_k127_5301669_0 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.0 1993.0
HFD1_k127_5311397_0 response regulator K07715 - - 5.968e-200 633.0
HFD1_k127_5311397_1 Signal transduction histidine kinase K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 464.0
HFD1_k127_5311397_2 - - - - 0.0000000000000000000000001233 117.0
HFD1_k127_5315126_0 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 604.0
HFD1_k127_5315126_1 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000483 257.0
HFD1_k127_5315711_0 Dolichyl-phosphate-mannose-protein mannosyltransferase K00721,K00786 - 2.4.1.83 9.204e-264 827.0
HFD1_k127_5315711_1 TIGRFAM sugar transferase, PEP-CTERM system associated K21303 - 2.7.8.40 1.74e-244 762.0
HFD1_k127_5315711_2 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 453.0
HFD1_k127_5315711_3 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000000000000000000000000000328 174.0
HFD1_k127_5315711_4 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000003207 164.0
HFD1_k127_5341160_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 2.688e-201 630.0
HFD1_k127_5341160_1 Protein of unknown function (DUF1439) - - - 0.0000000000000000000000000000000000000000000000002924 184.0
HFD1_k127_5341160_2 PIN domain - - - 0.000000000000000000000000002096 118.0
HFD1_k127_53476_0 Putative amidoligase enzyme (DUF2126) - - - 0.0 2054.0
HFD1_k127_53476_1 A predicted alpha-helical domain with a conserved ER motif. - - - 4.698e-291 900.0
HFD1_k127_53476_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 4.571e-196 621.0
HFD1_k127_53476_3 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000002916 141.0
HFD1_k127_53476_4 - - - - 0.000000000009969 71.0
HFD1_k127_5356717_0 Belongs to the ParA family K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 419.0
HFD1_k127_5356717_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 384.0
HFD1_k127_5356717_2 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 366.0
HFD1_k127_5356717_3 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000000000000000000000000000002783 215.0
HFD1_k127_5356717_4 peptidase activity, acting on L-amino acid peptides - - - 0.0000000000000000002605 102.0
HFD1_k127_5356717_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000006156 70.0
HFD1_k127_5376682_0 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 376.0
HFD1_k127_5376682_1 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009098 256.0
HFD1_k127_5376682_2 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000007124 182.0
HFD1_k127_5379845_0 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 430.0
HFD1_k127_5379845_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 307.0
HFD1_k127_5379845_2 Heavy-metal resistance - - - 0.00000000000000000000000003261 117.0
HFD1_k127_5379845_3 chemotaxis protein K03406 - - 0.00000000000000000001616 97.0
HFD1_k127_538763_0 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008059 493.0
HFD1_k127_538763_1 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 484.0
HFD1_k127_538763_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 464.0
HFD1_k127_538763_3 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 415.0
HFD1_k127_538763_4 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 382.0
HFD1_k127_538763_5 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000607 66.0
HFD1_k127_5388478_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 464.0
HFD1_k127_5388478_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 331.0
HFD1_k127_5399731_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 370.0
HFD1_k127_5399731_2 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0000000000000159 77.0
HFD1_k127_5399731_3 WHG domain - - - 0.0000001086 55.0
HFD1_k127_5401803_0 PFAM Cytochrome c, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 560.0
HFD1_k127_5401803_1 TIGRFAM ornithine aminotransferase K00819 - 2.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005718 466.0
HFD1_k127_5401803_2 Subtilase family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 408.0
HFD1_k127_5401803_3 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 289.0
HFD1_k127_5401803_4 ProQ/FINO family K03607 - - 0.0000000000000000000000000000000000000000000000000000000005672 207.0
HFD1_k127_5401803_5 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.000000276 54.0
HFD1_k127_5403615_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 533.0
HFD1_k127_5403615_1 Protein of unknown function (DUF2726) - - - 0.000000000000000000000000000000000000000000000000004744 191.0
HFD1_k127_5411901_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 1.5e-204 642.0
HFD1_k127_5411901_1 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 422.0
HFD1_k127_5411901_2 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 363.0
HFD1_k127_5420959_0 acyl-CoA dehydrogenase - - - 0.0 1126.0
HFD1_k127_5420959_1 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0 1075.0
HFD1_k127_5427794_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1270.0
HFD1_k127_5427794_1 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 308.0
HFD1_k127_5427794_2 - - - - 0.00000000001378 71.0
HFD1_k127_5434109_0 AMP-binding enzyme C-terminal domain - - - 1.592e-261 827.0
HFD1_k127_5435950_0 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000654 264.0
HFD1_k127_5435950_1 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000000000000000000000000000000000006237 204.0
HFD1_k127_543935_0 Transporter K11688,K21395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 454.0
HFD1_k127_543935_1 Signal transduction histidine kinase K11711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 322.0
HFD1_k127_5439353_0 metal-dependent phosphohydrolase HD sub domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 596.0
HFD1_k127_5439353_1 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005241 272.0
HFD1_k127_5439353_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000002761 211.0
HFD1_k127_5439353_3 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000002728 87.0
HFD1_k127_544037_0 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K13482 - 1.17.1.4 5.632e-254 790.0
HFD1_k127_544037_1 Xanthine dehydrogenase small subunit K13481 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 349.0
HFD1_k127_5444485_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 8.179e-237 760.0
HFD1_k127_5444485_1 Secretory lipase - - - 2.672e-215 682.0
HFD1_k127_5444485_2 poly-beta-hydroxybutyrate polymerase K03821 - - 2.887e-210 670.0
HFD1_k127_5444485_3 Alcohol dehydrogenase GroES-like domain - - - 4.577e-200 626.0
HFD1_k127_5444485_4 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006391 279.0
HFD1_k127_5444485_5 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000314 167.0
HFD1_k127_5444485_6 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000001043 154.0
HFD1_k127_5446447_0 Virulence factor membrane-bound polymerase, C-terminal - - - 2.277e-194 631.0
HFD1_k127_5446447_1 Major Facilitator Superfamily K08159,K19577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009996 580.0
HFD1_k127_5446447_2 IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 286.0
HFD1_k127_5446447_3 sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.00000000000000000000000000000000000000000000000000000001091 200.0
HFD1_k127_5446447_4 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000007343 194.0
HFD1_k127_5451099_0 4-alpha-glucanotransferase K00705,K06044 - 2.4.1.25,5.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 475.0
HFD1_k127_5451099_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 446.0
HFD1_k127_5460597_0 PFAM Amidohydrolase 3 - - - 0.0 1035.0
HFD1_k127_5460597_1 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 293.0
HFD1_k127_5472434_0 Histidine kinase - - - 1.861e-263 823.0
HFD1_k127_5472434_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 548.0
HFD1_k127_5472434_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 370.0
HFD1_k127_5472434_3 membrane-associated Zn-dependent proteases 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001025 235.0
HFD1_k127_5477400_0 -O-antigen K21003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 569.0
HFD1_k127_5477400_1 Glycosyl transferases group 1 K00786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 515.0
HFD1_k127_5477400_2 membrane K21004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 455.0
HFD1_k127_5477400_3 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 390.0
HFD1_k127_5477400_4 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000005373 254.0
HFD1_k127_5477400_5 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000408 63.0
HFD1_k127_5477400_6 - - - - 0.000002443 50.0
HFD1_k127_5480472_0 LRV protein FeS4 cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006361 277.0
HFD1_k127_5480472_1 - - - - 0.0000000000000000000000000000000000000000000000000002973 186.0
HFD1_k127_5480472_2 Aminotransferase class-V K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000825 186.0
HFD1_k127_5480472_3 PFAM NifZ family protein K02597 - - 0.00000000000000000000000000000000006097 136.0
HFD1_k127_5480472_4 PFAM NifZ family protein K02597 - - 0.000000000000000000000000121 109.0
HFD1_k127_548220_0 homolog of phage Mu protein gp47 - - - 5.781e-250 796.0
HFD1_k127_5495817_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 3.188e-232 724.0
HFD1_k127_5495817_1 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 415.0
HFD1_k127_5495817_2 - - - - 0.000000002433 68.0
HFD1_k127_550141_0 PFAM Aminotransferase class I and II K00832 - 2.6.1.57 9.412e-223 695.0
HFD1_k127_550141_1 Glyoxal oxidase N-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 440.0
HFD1_k127_550141_2 Polyhydroxyalkanoate depolymerase, intracellular K05973 - 3.1.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001147 280.0
HFD1_k127_550141_3 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000000004531 98.0
HFD1_k127_5504050_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.461e-290 895.0
HFD1_k127_5504050_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 312.0
HFD1_k127_55303_0 peptide transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 481.0
HFD1_k127_55303_1 Protein of unknown function (DUF3348) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009181 245.0
HFD1_k127_55303_2 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.00000000000000000000000000000000000000000000000008867 182.0
HFD1_k127_5553768_0 ABC transporter K06020 - 3.6.3.25 0.0 1055.0
HFD1_k127_5553768_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004357 263.0
HFD1_k127_5553768_2 Belongs to the UPF0235 family K09131 - - 0.00000000000000000000000000000000006845 138.0
HFD1_k127_5556580_0 Protein of unknown function (DUF445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 537.0
HFD1_k127_5556580_2 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 316.0
HFD1_k127_5556580_3 photoreceptor activity K11527 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 291.0
HFD1_k127_5556580_4 Putative modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005981 246.0
HFD1_k127_5556580_5 PFAM ribonuclease H K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000003707 194.0
HFD1_k127_5556580_6 acetyltransferase - - - 0.000000000000000000000000000000000000000000000001976 183.0
HFD1_k127_5556580_7 Pectinacetylesterase - - - 0.00006125 48.0
HFD1_k127_5566651_0 Protein of unknown function (DUF692) K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 340.0
HFD1_k127_5566651_1 Putative DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000001605 209.0
HFD1_k127_5566651_2 TonB C terminal K03646 - - 0.0000000000000000000000000000000006061 138.0
HFD1_k127_5566651_3 Predicted integral membrane protein (DUF2282) - - - 0.000000000000000000000000000000001619 133.0
HFD1_k127_5598132_0 Transcriptional regulator crp fnr family K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 312.0
HFD1_k127_5598132_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.000000000000000000000000000000000000000000000000000000000004476 213.0
HFD1_k127_5598132_2 ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000005533 158.0
HFD1_k127_5598132_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K00926 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.7.2.2 0.00000000000001519 81.0
HFD1_k127_5599873_0 His Kinase A (phosphoacceptor) domain - - - 1.382e-202 649.0
HFD1_k127_5599873_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 511.0
HFD1_k127_5599873_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000755 124.0
HFD1_k127_5614920_0 TIGRFAM type IV-A pilus assembly ATPase PilB K02454,K02504,K02652 - - 1.739e-197 623.0
HFD1_k127_5614920_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 358.0
HFD1_k127_5635701_0 desaturase K00508 - 1.14.19.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 558.0
HFD1_k127_5635701_1 TIGRFAM phenylacetate-CoA oxygenase reductase, PaaK subunit K02613,K15983 - 1.14.13.142 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 416.0
HFD1_k127_5635701_2 OmpA-like transmembrane domain - - - 0.000000000000000000000000000003706 123.0
HFD1_k127_5647430_0 Flagellar motor switch K02416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 606.0
HFD1_k127_5647430_1 Role in flagellar biosynthesis K02421 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 415.0
HFD1_k127_5647430_10 Flagellar biosynthesis protein, FliO K02418 - - 0.000000000000000000000000005027 114.0
HFD1_k127_5647430_11 flagellar export protein FliJ K02413 - - 0.000000000000000000002009 100.0
HFD1_k127_5647430_2 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 396.0
HFD1_k127_5647430_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 377.0
HFD1_k127_5647430_4 Flagellar protein export ATPase FliI K02412 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 316.0
HFD1_k127_5647430_5 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000943 274.0
HFD1_k127_5647430_6 Flagellar motor switch protein fliN K02417,K03225 - - 0.000000000000000000000000000000000000000000000000000000000001124 213.0
HFD1_k127_5647430_7 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000000000000001677 171.0
HFD1_k127_5647430_8 Flagellar hook-length control protein K02414 - - 0.0000000000000000000000000000000000000000003449 175.0
HFD1_k127_5647430_9 Role in flagellar biosynthesis K02420 - - 0.0000000000000000000000000000000000000005198 149.0
HFD1_k127_5649784_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 5.104e-311 956.0
HFD1_k127_5649784_1 Belongs to the transcriptional regulatory Fis family K03557 - - 0.00000000000000000000000000000000000000004757 151.0
HFD1_k127_5665446_0 IgA Peptidase M64 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002213 261.0
HFD1_k127_5665446_1 transferase activity, transferring glycosyl groups K20276 - - 0.00000000000000000000009857 105.0
HFD1_k127_5667239_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 509.0
HFD1_k127_5667239_1 TIGRFAM phosphate regulon sensor kinase PhoR K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000267 176.0
HFD1_k127_5678509_0 Esterase PHB depolymerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 355.0
HFD1_k127_5678509_1 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 330.0
HFD1_k127_5678509_2 response regulator - - - 0.00000000000002776 77.0
HFD1_k127_5683624_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 445.0
HFD1_k127_5683624_1 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001191 274.0
HFD1_k127_5698017_0 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 GO:0000166,GO:0003674,GO:0003824,GO:0003960,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009987,GO:0010941,GO:0016491,GO:0016651,GO:0016655,GO:0019362,GO:0019637,GO:0034641,GO:0036094,GO:0042802,GO:0042803,GO:0042981,GO:0043067,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0048038,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0051186,GO:0055086,GO:0055114,GO:0065007,GO:0070402,GO:0071704,GO:0072524,GO:0097159,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009316 402.0
HFD1_k127_5698017_1 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000123 290.0
HFD1_k127_5703472_0 Isocitrate dehydrogenase K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 604.0
HFD1_k127_5703472_1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 569.0
HFD1_k127_5703472_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 379.0
HFD1_k127_5703472_3 Fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 320.0
HFD1_k127_5703472_4 PFAM regulatory protein TetR K22105 - - 0.0000000000000000000000000000004334 130.0
HFD1_k127_5729527_0 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 446.0
HFD1_k127_5729527_1 preprotein translocase K03210 - - 0.0000000000000000000000000000000000000000004001 159.0
HFD1_k127_5729527_2 Belongs to the UPF0250 family K09158 - - 0.00000000000000000000000000000001022 128.0
HFD1_k127_5729527_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000001074 64.0
HFD1_k127_5732003_0 Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates K01426 - 3.5.1.4 3.695e-215 669.0
HFD1_k127_5732003_1 FIST C domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 546.0
HFD1_k127_5732003_2 Histidine kinase K10125 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 511.0
HFD1_k127_5732003_3 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 480.0
HFD1_k127_5732003_4 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 465.0
HFD1_k127_5732003_5 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 462.0
HFD1_k127_5732003_6 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009825 439.0
HFD1_k127_5732003_7 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000001518 181.0
HFD1_k127_5732003_8 Pfam Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000001848 183.0
HFD1_k127_5732003_9 CheC-like family K03410 - - 0.000000000000000000000000000000000000000000000001195 184.0
HFD1_k127_5749061_0 Belongs to the thiolase family K00632 - 2.3.1.16 8.124e-231 720.0
HFD1_k127_5749061_1 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 448.0
HFD1_k127_5749061_2 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001201 252.0
HFD1_k127_5749061_3 Alpha beta hydrolase - - - 0.000000000000000000000000000114 117.0
HFD1_k127_5752875_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1373.0
HFD1_k127_5752875_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1097.0
HFD1_k127_5752875_2 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 551.0
HFD1_k127_5752875_3 PFAM MotA TolQ ExbB proton channel K03561,K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 381.0
HFD1_k127_5752875_4 Phosphoglycerate mutase family K08296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006271 243.0
HFD1_k127_5752875_5 system-associated acyl-CoA thioesterase K07107 - - 0.000000000000000000000000000000000000000000000000000000000000177 215.0
HFD1_k127_5752875_6 Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000000000000000000000000000000003741 205.0
HFD1_k127_5752875_8 COG0810 Periplasmic protein TonB, links inner and outer membranes K03646 - - 0.00001662 55.0
HFD1_k127_5755174_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 1.05e-262 838.0
HFD1_k127_5755174_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 5.102e-226 708.0
HFD1_k127_5755174_2 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 591.0
HFD1_k127_5755174_4 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000508 152.0
HFD1_k127_5755174_5 - - - - 0.0000000000000000000000000004392 115.0
HFD1_k127_5755174_6 Papain family cysteine protease - - - 0.00000000000002539 83.0
HFD1_k127_5765596_0 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 609.0
HFD1_k127_5765596_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 400.0
HFD1_k127_5765596_2 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000002351 190.0
HFD1_k127_5766550_0 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000897 452.0
HFD1_k127_5766550_1 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000008714 149.0
HFD1_k127_5766550_2 Glycosyltransferase like family 2 - - - 0.000000000000000000000000007956 111.0
HFD1_k127_5788230_0 PFAM Orn Lys Arg decarboxylase major region K01584 - 4.1.1.19 0.0 1368.0
HFD1_k127_5788230_1 C-terminal region of band_7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 388.0
HFD1_k127_5788230_2 Membrane protein implicated in regulation of membrane protease activity - - - 0.0000000000000000000000000000000000002204 145.0
HFD1_k127_5788230_3 Histidine kinase-like ATPases - - - 0.0000000000000000000000002819 105.0
HFD1_k127_578893_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 574.0
HFD1_k127_578893_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 426.0
HFD1_k127_5789129_0 NADPH-dependent FMN reductase K11811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 409.0
HFD1_k127_5789129_1 Phosphate acetyl/butaryl transferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 372.0
HFD1_k127_5789129_2 ArsC family K00537 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000145 203.0
HFD1_k127_5789129_3 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000002575 198.0
HFD1_k127_5789129_4 Lipocalin-like domain K03098 - - 0.0000000000000000000000000000000000000000000003528 177.0
HFD1_k127_5789129_5 Haem-degrading K11477 - - 0.0000000000000000000000000000000000000000008119 162.0
HFD1_k127_5789129_6 - - - - 0.00000000000000000000000000000000017 144.0
HFD1_k127_5789129_7 - - - - 0.00000000000000000000001632 105.0
HFD1_k127_5793679_0 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 351.0
HFD1_k127_5793679_1 L-proline glycine betaine ABC transport system permease protein ProW K02001,K02002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 337.0
HFD1_k127_5793679_2 Substrate binding domain of ABC-type glycine betaine transport system K02002 - - 0.0000005513 51.0
HFD1_k127_581369_0 Alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 355.0
HFD1_k127_581369_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000009104 226.0
HFD1_k127_5817047_0 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 388.0
HFD1_k127_5817047_1 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.00000000000000000000000000000002552 128.0
HFD1_k127_5819404_0 chemotaxis K03406,K03776,K05874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 423.0
HFD1_k127_5819404_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000001594 223.0
HFD1_k127_5831825_0 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 2.762e-212 664.0
HFD1_k127_5831825_1 TRAP dicarboxylate transporter, DctM subunit K03299 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 556.0
HFD1_k127_5831825_2 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 456.0
HFD1_k127_5831825_3 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 353.0
HFD1_k127_5831825_4 molybdenum cofactor K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002403 273.0
HFD1_k127_5831825_5 Belongs to the UPF0307 family K09889 - - 0.00000000000000000000000000000000000000000000000000005464 199.0
HFD1_k127_5832072_0 Belongs to the protein N5-glutamine methyltransferase family K07320 - 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006734 447.0
HFD1_k127_5832072_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 371.0
HFD1_k127_5832072_2 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 357.0
HFD1_k127_5832072_3 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002098 253.0
HFD1_k127_5832072_4 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000124 190.0
HFD1_k127_5832072_6 Alkyl hydroperoxide reductase K03387 - - 0.0000000000000000000000000000000000000000009052 157.0
HFD1_k127_5832072_7 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000000005563 139.0
HFD1_k127_5832072_8 Predicted membrane protein (DUF2238) K08984 - - 0.000001045 50.0
HFD1_k127_5852313_0 Histidine kinase - - - 1.213e-268 851.0
HFD1_k127_5852313_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000008403 228.0
HFD1_k127_5852313_2 Nucleotidyl transferase K00992 - 2.7.7.99 0.00000000000000000000000000001246 121.0
HFD1_k127_5852313_4 - - - - 0.0004248 49.0
HFD1_k127_5861332_0 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 433.0
HFD1_k127_5861332_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 375.0
HFD1_k127_5861332_2 Protein of unknown function (DUF541) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001754 264.0
HFD1_k127_5861332_3 TIGRFAM phasin family protein - - - 0.000000000000000000000000001395 112.0
HFD1_k127_5861924_0 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000005334 222.0
HFD1_k127_5861924_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000005255 200.0
HFD1_k127_5861924_2 CHASE3 domain - - - 0.0000000000000699 71.0
HFD1_k127_5863581_0 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 423.0
HFD1_k127_5863581_1 Nicotinamide mononucleotide transporter K03811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000101 278.0
HFD1_k127_5863581_2 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009887 252.0
HFD1_k127_5863581_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000000000000001148 121.0
HFD1_k127_5863581_4 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 0.000000000000000001267 85.0
HFD1_k127_5882826_0 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0 1139.0
HFD1_k127_5882826_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000003255 230.0
HFD1_k127_5886638_0 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 608.0
HFD1_k127_5886638_1 PFAM OmpW family protein K07275 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005396 258.0
HFD1_k127_5900591_0 sensor histidine kinase response regulator - - - 0.0 1234.0
HFD1_k127_5911808_0 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 1.366e-227 730.0
HFD1_k127_5914156_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K05962 - 2.7.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 399.0
HFD1_k127_5914156_1 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 GO:0003674,GO:0003824,GO:0003841,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042171,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071617,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 389.0
HFD1_k127_5914156_2 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 339.0
HFD1_k127_5914156_3 EF-hand, calcium binding motif - - - 0.00000000000000000000001651 108.0
HFD1_k127_5914156_4 Metal binding domain of Ada K00567,K10778 GO:0001130,GO:0003674,GO:0003700,GO:0003824,GO:0003908,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006355,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016740,GO:0016741,GO:0018125,GO:0018193,GO:0018198,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044728,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0046872,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070988,GO:0071704,GO:0080090,GO:0080111,GO:0090304,GO:0140110,GO:1901360,GO:1901564,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 2.1.1.63 0.000000000009172 66.0
HFD1_k127_5926813_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1379.0
HFD1_k127_5926813_1 diguanylate cyclase K13069,K21085 - 2.7.7.65 0.0000000000000000006543 89.0
HFD1_k127_5928663_0 Eukaryotic-type carbonic anhydrase K01674 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 383.0
HFD1_k127_5928663_1 TIGRFAM Drug resistance transporter Bcr CflA subfamily K07552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008147 344.0
HFD1_k127_5928663_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 293.0
HFD1_k127_5928663_3 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000006581 247.0
HFD1_k127_5929372_0 twitching motility protein K02670 - - 1.762e-222 694.0
HFD1_k127_5929372_1 twitching motility protein K02669,K12203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 367.0
HFD1_k127_5929372_2 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 303.0
HFD1_k127_5929372_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0008442,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.1.1.31,1.1.1.60 0.0000000000000000000004606 97.0
HFD1_k127_5934391_0 Permease, YjgP YjgQ K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 344.0
HFD1_k127_5934391_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009057 334.0
HFD1_k127_5941571_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00956 - 2.7.7.4 1.503e-238 743.0
HFD1_k127_5941571_1 Sulfate adenylyltransferase K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 588.0
HFD1_k127_5941571_2 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000007325 130.0
HFD1_k127_5948531_0 phosphoserine phosphatase K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 404.0
HFD1_k127_5948531_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639,K00652,K00654 - 2.3.1.29,2.3.1.47,2.3.1.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 385.0
HFD1_k127_5948531_3 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000001261 58.0
HFD1_k127_595555_0 MacB-like periplasmic core domain K02004 - - 1.446e-201 631.0
HFD1_k127_595555_1 ABC transporter, ATP-binding protein K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 285.0
HFD1_k127_5974966_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1217.0
HFD1_k127_5974966_1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 322.0
HFD1_k127_5974966_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003516 280.0
HFD1_k127_5974966_3 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000000000000001001 115.0
HFD1_k127_5978663_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 385.0
HFD1_k127_6024038_0 peptidase M48, Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 350.0
HFD1_k127_6024038_1 PFAM transposase, IS111A IS1328 IS1533 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008153 322.0
HFD1_k127_6024038_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000001526 259.0
HFD1_k127_6025240_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1375.0
HFD1_k127_6025240_1 TIGRFAM methionine aminopeptidase, type I K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000008802 236.0
HFD1_k127_6038170_0 Domain of unknown function (DUF3391) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 523.0
HFD1_k127_6038170_1 alpha/beta hydrolase fold K01046 - 3.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005695 370.0
HFD1_k127_6051257_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 454.0
HFD1_k127_6051257_1 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 307.0
HFD1_k127_6051257_2 Cytochrome B561 K12262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 287.0
HFD1_k127_6051257_3 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 292.0
HFD1_k127_6051257_4 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008203 274.0
HFD1_k127_6051257_5 GGDEF domain K21019 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000002477 267.0
HFD1_k127_6051257_6 signal transduction protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003859 258.0
HFD1_k127_6051257_7 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000004257 153.0
HFD1_k127_6056693_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.492e-298 921.0
HFD1_k127_6056693_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 521.0
HFD1_k127_6056693_2 PFAM Lytic transglycosylase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004211 275.0
HFD1_k127_6056693_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000001359 246.0
HFD1_k127_6064559_0 Dehydrogenase E1 component K00164 - 1.2.4.2 1.072e-226 704.0
HFD1_k127_6064559_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 436.0
HFD1_k127_6064559_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 376.0
HFD1_k127_6073365_0 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 449.0
HFD1_k127_6073365_1 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.00000000000000000000000000000000000000000000000000003455 188.0
HFD1_k127_60772_0 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 1.512e-200 631.0
HFD1_k127_60772_1 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 436.0
HFD1_k127_60772_2 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007319 419.0
HFD1_k127_60772_3 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 0.0000000000000000000000000000000002063 132.0
HFD1_k127_60772_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000006435 64.0
HFD1_k127_6078254_0 4Fe-4S dicluster domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 486.0
HFD1_k127_6078254_1 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.00000000000000000000000000000000001386 140.0
HFD1_k127_607950_0 Phospholipase D Transphosphatidylase K06132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009127 453.0
HFD1_k127_607950_1 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 394.0
HFD1_k127_607950_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006913 330.0
HFD1_k127_607950_3 - - - - 0.0000000000000000000000000000000000000000000003137 171.0
HFD1_k127_607950_4 Ion transport protein - - - 0.0000000000000000000001194 103.0
HFD1_k127_6079755_0 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 329.0
HFD1_k127_6079755_1 Bacterial transcriptional repressor C-terminal K09017 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 324.0
HFD1_k127_6079755_2 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000000000000000000000000001085 243.0
HFD1_k127_6079755_3 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.00000000000000000000000000002563 123.0
HFD1_k127_6084988_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1347.0
HFD1_k127_6084988_1 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 419.0
HFD1_k127_6086758_0 phosphoesterase, PHP K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 497.0
HFD1_k127_6086758_1 Belongs to the SUA5 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 338.0
HFD1_k127_6086758_2 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000000000003684 193.0
HFD1_k127_6086758_3 Glutaredoxin - - - 0.00000004551 55.0
HFD1_k127_6093080_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 4.853e-300 925.0
HFD1_k127_6093080_1 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000005207 211.0
HFD1_k127_6093080_2 Molybdopterin biosynthesis MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000001809 213.0
HFD1_k127_6093080_3 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000005472 154.0
HFD1_k127_6093080_4 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000000004021 135.0
HFD1_k127_6093080_5 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.000000000000000000001045 99.0
HFD1_k127_6120332_0 Site-specific recombinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 342.0
HFD1_k127_6120332_1 Glutathione S-transferase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000212 283.0
HFD1_k127_6120332_2 ApaG domain K06195 - - 0.000000000000000000000000000000000000000000000000000000000004685 216.0
HFD1_k127_6120332_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000002045 145.0
HFD1_k127_612239_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 2.221e-289 897.0
HFD1_k127_612239_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 355.0
HFD1_k127_612239_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008146 273.0
HFD1_k127_612470_0 Response regulator receiver - - - 7.506e-228 713.0
HFD1_k127_612470_1 COG2133 Glucose sorbosone dehydrogenases - - - 1.806e-216 680.0
HFD1_k127_612470_10 CsbD-like - - - 0.00000000000004069 74.0
HFD1_k127_612470_2 AsmA-like C-terminal region K07289,K07290 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 465.0
HFD1_k127_612470_3 Catalase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 302.0
HFD1_k127_612470_4 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding - - - 0.000000000000000000000000000000000000000000000000000000007345 202.0
HFD1_k127_612470_5 - - - - 0.00000000000000000000000000000000000000000000000003188 190.0
HFD1_k127_612470_6 Predicted membrane protein (DUF2177) - - - 0.0000000000000000000000000000000000000000001215 162.0
HFD1_k127_612470_7 Catalase K03781 - 1.11.1.6 0.00000000000000000000000000002112 125.0
HFD1_k127_612470_8 Response regulator, receiver K07677 - 2.7.13.3 0.000000000000000000000001083 109.0
HFD1_k127_612470_9 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000006266 89.0
HFD1_k127_6133036_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008358 486.0
HFD1_k127_6133036_1 pyridine nucleotide-disulphide oxidoreductase dimerisation region K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 329.0
HFD1_k127_6137397_0 Major Facilitator Superfamily K03446 - - 4.472e-261 814.0
HFD1_k127_6137397_1 Outer membrane efflux protein K18139,K18903 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 572.0
HFD1_k127_6137397_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 462.0
HFD1_k127_6137397_3 PFAM peptidase S16 lon domain protein K07157 - - 0.000000000000000000000000000000000000000000000000005778 187.0
HFD1_k127_6137838_0 PFAM AMP-dependent synthetase and ligase K00666 - - 9.505e-311 963.0
HFD1_k127_6137838_1 belongs to the aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 1.227e-250 779.0
HFD1_k127_6137838_2 S4 domain K14761 - - 0.00000000000000000000000004405 116.0
HFD1_k127_6137838_3 - - - - 0.00000000000000000003988 92.0
HFD1_k127_6138500_0 flagellar hook-associated protein K02396 - - 1.827e-207 663.0
HFD1_k127_6138500_1 signal transduction protein containing EAL and modified HD-GYP domains - - - 2.109e-197 621.0
HFD1_k127_6138500_2 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 482.0
HFD1_k127_6138500_3 Phosphoesterase DHHA1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 471.0
HFD1_k127_6138500_4 Belongs to the bacterial flagellin family K02397 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 465.0
HFD1_k127_6138500_5 TIGRFAM flagellar rod assembly protein muramidase FlgJ K02395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 386.0
HFD1_k127_6138500_6 diguanylate cyclase K21019 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000001355 263.0
HFD1_k127_6138500_7 - - - - 0.0000004717 58.0
HFD1_k127_613995_0 HemY protein N-terminus K02498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 586.0
HFD1_k127_613995_1 HemX, putative uroporphyrinogen-III C-methyltransferase K02496,K13543 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000001723 163.0
HFD1_k127_618046_0 PFAM Integrase catalytic region - - - 1.468e-243 762.0
HFD1_k127_618046_1 PFAM IstB domain protein ATP-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002531 264.0
HFD1_k127_6187615_0 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 556.0
HFD1_k127_6187615_1 PFAM alpha beta hydrolase fold K19707 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 424.0
HFD1_k127_6187615_2 Esterase PHB depolymerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 417.0
HFD1_k127_6187615_3 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000001263 211.0
HFD1_k127_6187615_4 histidine kinase A domain protein - - - 0.00000000000000000004293 96.0
HFD1_k127_6200789_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 2.136e-252 780.0
HFD1_k127_6200789_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 3.194e-216 674.0
HFD1_k127_6200789_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 5.876e-197 617.0
HFD1_k127_6200789_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 576.0
HFD1_k127_6200789_4 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001468 275.0
HFD1_k127_6203789_0 Required for the activity of the bacterial periplasmic transport system of putrescine K11073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 592.0
HFD1_k127_6203789_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 483.0
HFD1_k127_6203789_2 transport system permease K11075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 461.0
HFD1_k127_6203789_3 transport system permease K11074 - - 0.000000000000000000000000000000000000000000000001044 191.0
HFD1_k127_6216232_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005441 284.0
HFD1_k127_6219941_0 PFAM Helix-turn-helix, type 11 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 364.0
HFD1_k127_6219941_1 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000000000000005073 146.0
HFD1_k127_6219941_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000003705 131.0
HFD1_k127_6233311_0 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K05685 - - 0.0 1041.0
HFD1_k127_6233311_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K13888 - - 0.0000000000000000000000000006991 115.0
HFD1_k127_6247739_0 Protein of unknown function (DUF3106) - - - 0.00000000000000000000000000000000000000000004647 173.0
HFD1_k127_6247739_1 Protein of unknown function (DUF3619) - - - 0.000000000000000000000002305 112.0
HFD1_k127_6247739_2 metalloendopeptidase activity K08602 - - 0.000000000000000001055 98.0
HFD1_k127_6247739_3 RNA polymerase, sigma-24 subunit, ECF subfamily K03088 - - 0.000000000000000005023 83.0
HFD1_k127_6251964_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 1.611e-197 621.0
HFD1_k127_6251964_1 Type IV pilus biogenesis stability protein PilW K02656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000104 259.0
HFD1_k127_6251964_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000001015 141.0
HFD1_k127_6255142_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 503.0
HFD1_k127_6255142_1 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 284.0
HFD1_k127_6255142_2 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000005178 213.0
HFD1_k127_6255142_3 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000001111 190.0
HFD1_k127_6255142_4 Ribosomal protein L30 K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000003136 106.0
HFD1_k127_6257417_0 Belongs to the aldehyde dehydrogenase family K00138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 548.0
HFD1_k127_6257417_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007459 271.0
HFD1_k127_6257417_2 Belongs to the ArsC family K00537 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000002247 205.0
HFD1_k127_6258835_0 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 9.944e-207 665.0
HFD1_k127_6258835_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000838 267.0
HFD1_k127_6258835_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000001841 173.0
HFD1_k127_6258835_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000007535 113.0
HFD1_k127_6264698_0 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 439.0
HFD1_k127_6264698_1 Binding-protein-dependent transport system inner membrane component K02029,K09971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 370.0
HFD1_k127_6264698_2 pilus assembly K02676 - - 0.00000000000000000000000000000000000000000000000000000000001733 208.0
HFD1_k127_6264698_3 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000006133 154.0
HFD1_k127_6264698_4 - - - - 0.000000000000000000000000003787 112.0
HFD1_k127_6283848_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 488.0
HFD1_k127_6283848_1 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 431.0
HFD1_k127_6283848_10 anti-sigma regulatory factor K17752 - 2.7.11.1 0.000000000000000000000001668 108.0
HFD1_k127_6283848_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 410.0
HFD1_k127_6283848_3 RsbT co-antagonist protein rsbRD N-terminal domain K17763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 325.0
HFD1_k127_6283848_4 anti-sigma regulatory factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000804 311.0
HFD1_k127_6283848_5 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 305.0
HFD1_k127_6283848_6 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001147 252.0
HFD1_k127_6283848_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000004061 234.0
HFD1_k127_6283848_8 Anti-sigma-K factor rskA - - - 0.0000000000000000000000000000000000000000000000000000000000000001868 228.0
HFD1_k127_6283848_9 PFAM Sulfate transporter antisigma-factor antagonist STAS K17762 - - 0.00000000000000000000000000000000000000000000005944 172.0
HFD1_k127_6288985_0 TIGRFAM general secretory pathway protein E K02454 - - 1.464e-265 822.0
HFD1_k127_6288985_1 general secretion pathway protein K02453 - - 5.97e-237 754.0
HFD1_k127_6288985_2 general secretion pathway protein K02455 - - 1.358e-198 625.0
HFD1_k127_6288985_3 PFAM ATPase family associated with various cellular activities (AAA) K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006211 593.0
HFD1_k127_6288985_4 General secretion pathway K02461 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 569.0
HFD1_k127_6288985_5 5'-nucleotidase K01081 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 483.0
HFD1_k127_6288985_6 Type II secretion system (T2SS), protein N K02463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000781 396.0
HFD1_k127_6288985_7 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004197 226.0
HFD1_k127_6288985_8 PFAM General secretion pathway, M protein K02462 - - 0.000000000000000000000000000000000000000000000000001913 187.0
HFD1_k127_6288985_9 PFAM General secretion pathway protein K K02460 - - 0.000000000000000000000000000000000006706 144.0
HFD1_k127_6299013_0 DNA topoisomerase III K03169 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 351.0
HFD1_k127_6299013_1 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 310.0
HFD1_k127_6299013_2 Cysteine-rich motif following a subset of SET domains K07117 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003384 274.0
HFD1_k127_6311598_0 Belongs to the peptidase M12A family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 601.0
HFD1_k127_6311598_1 Cytochrome B561 - - - 0.000000000000000000000000000000000000000000000000000000000000006461 222.0
HFD1_k127_6311598_2 PFAM cytochrome c - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000003583 49.0
HFD1_k127_6314681_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.397e-273 843.0
HFD1_k127_6314681_1 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 473.0
HFD1_k127_6314681_2 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 461.0
HFD1_k127_6314681_3 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000000000000000000000001797 132.0
HFD1_k127_6317073_0 C-terminal, D2-small domain, of ClpB protein K11907 - - 9.858e-230 734.0
HFD1_k127_6317073_1 Type VI secretion protein K11896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 553.0
HFD1_k127_6317073_2 Pfam:T6SS_VasB K11895 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 394.0
HFD1_k127_6317397_0 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 354.0
HFD1_k127_6317721_0 TonB dependent receptor K02014 - - 2.436e-208 665.0
HFD1_k127_6317721_1 PFAM FMN-dependent alpha-hydroxy acid dehydrogenase K00101,K16422 - 1.1.2.3,1.1.3.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 541.0
HFD1_k127_6317721_2 PFAM cytochrome B561 - - - 0.00000000000000000000000000000000000000000000000001346 182.0
HFD1_k127_6347821_0 HNH nucleases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 365.0
HFD1_k127_6347821_1 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 301.0
HFD1_k127_6347821_2 cyclic nucleotide-binding - - - 0.0000000000000001089 81.0
HFD1_k127_6350095_0 RNB K01147 - 3.1.13.1 0.0 1139.0
HFD1_k127_6350095_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 445.0
HFD1_k127_6350095_2 Uncharacterised protein family (UPF0227) K07000 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 282.0
HFD1_k127_6350095_3 TIGRFAM TonB family protein K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005109 277.0
HFD1_k127_6350095_4 Endonuclease/Exonuclease/phosphatase family K07004 - - 0.000000000000000000000000000000000000000000000000000000000000000006691 229.0
HFD1_k127_6350095_5 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000155 219.0
HFD1_k127_6350095_6 Belongs to the peptidase S8 family - - - 0.00000000000001002 84.0
HFD1_k127_6350496_0 AcrB/AcrD/AcrF family K18138 - - 0.0 1691.0
HFD1_k127_6350496_1 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007543 604.0
HFD1_k127_6350496_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 569.0
HFD1_k127_6350496_3 phosphoglycerate mutase K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 333.0
HFD1_k127_6350496_4 MAATS-type transcriptional repressor, C-terminal region K03577 - - 0.0000000000000000000000000000000000000000000000000000000000000007445 226.0
HFD1_k127_6350496_5 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000002596 183.0
HFD1_k127_6350496_6 Domain of unknown function (DUF1840) - - - 0.00000000000000000000000005362 110.0
HFD1_k127_6350891_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 3.536e-285 882.0
HFD1_k127_6350891_1 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 377.0
HFD1_k127_6350891_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 328.0
HFD1_k127_6350891_3 AraC family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006869 270.0
HFD1_k127_6350891_4 general secretion pathway protein K02456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001655 254.0
HFD1_k127_6350891_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000000000000000000000000000000000000000004225 233.0
HFD1_k127_6350891_6 general secretion pathway protein H K02457 - - 0.000000000000002502 78.0
HFD1_k127_6350891_7 general secretion pathway protein K02452 - - 0.0000000004982 69.0
HFD1_k127_6353181_0 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007468 520.0
HFD1_k127_6359246_0 transcriptional regulator K13634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 584.0
HFD1_k127_6359246_1 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 530.0
HFD1_k127_6359246_2 Permease, YjgP YjgQ K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 504.0
HFD1_k127_6359246_3 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 347.0
HFD1_k127_6359246_4 Permease, YjgP YjgQ K07091 - - 0.0000000000000000000000000000000000000000000000000000009822 197.0
HFD1_k127_6359246_5 CbiX K03795 - 4.99.1.3 0.000000000000000000000000000000000000000000000000006524 183.0
HFD1_k127_6359246_6 - - - - 0.0000000000000000000000000003931 124.0
HFD1_k127_6371064_0 acetyl-coa hydrolase - - - 1.179e-300 938.0
HFD1_k127_6371064_1 Ubiquinol oxidase, subunit I K00425 - 1.10.3.14 2.399e-294 914.0
HFD1_k127_6371064_10 Putative DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000626 194.0
HFD1_k127_6371064_11 - - - - 0.0000000000000000000000000000000000000008786 151.0
HFD1_k127_6371064_12 Protein of unknown function (DUF2892) - - - 0.00000000000000000005725 92.0
HFD1_k127_6371064_13 - - - - 0.0000001998 55.0
HFD1_k127_6371064_2 transcriptional regulator - - - 4.144e-201 643.0
HFD1_k127_6371064_3 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 465.0
HFD1_k127_6371064_4 Protein of unknown function (DUF692) K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 455.0
HFD1_k127_6371064_5 AraC family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 437.0
HFD1_k127_6371064_6 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 404.0
HFD1_k127_6371064_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 347.0
HFD1_k127_6371064_8 COG1309 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 344.0
HFD1_k127_6371064_9 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002116 241.0
HFD1_k127_6381642_0 AAA ATPase domain - - - 0.0 1077.0
HFD1_k127_6381642_1 Transcriptional regulatory protein, C terminal - - - 0.0000000001306 69.0
HFD1_k127_638991_0 DNA helicase K03657 - 3.6.4.12 2.485e-280 874.0
HFD1_k127_638991_1 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001099 276.0
HFD1_k127_638991_2 Protein of unknown function (DUF1571) - - - 0.0000000000000000000000000000000000000000000000000000000000000422 225.0
HFD1_k127_638991_3 NYN domain - - - 0.000000000000000000000000000000000000000001173 158.0
HFD1_k127_6392980_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0 1016.0
HFD1_k127_6392980_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K00533,K18006 - 1.12.1.2,1.12.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 604.0
HFD1_k127_6392980_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000001058 184.0
HFD1_k127_6392980_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000008345 135.0
HFD1_k127_6392980_4 Sugar (and other) transporter K08151 - - 0.0000000000000000000000007785 104.0
HFD1_k127_6398990_0 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 552.0
HFD1_k127_6398990_1 SIR2-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 356.0
HFD1_k127_6398990_2 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.00000000000000000000000000000000000000000004928 164.0
HFD1_k127_6408663_0 PFAM AMP-dependent synthetase and ligase K04784 - - 7.372e-233 737.0
HFD1_k127_6426780_0 TonB dependent receptor K02014 - - 5.635e-274 857.0
HFD1_k127_6426780_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 6.925e-254 786.0
HFD1_k127_6426780_2 peptidase K08259 - 3.4.24.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 366.0
HFD1_k127_6426780_3 Pyridine nucleotide-disulphide oxidoreductase K05297,K12265 - 1.18.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 291.0
HFD1_k127_6426780_4 Protein of unknown function (DUF721) - - - 0.0000000000000000000000000000001964 126.0
HFD1_k127_6426780_5 - - - - 0.00000001029 61.0
HFD1_k127_6427183_0 Bacterial type II/III secretion system short domain K02453 - - 0.00000000000000000000000000000000000000000000000000002446 200.0
HFD1_k127_6427183_2 - - - - 0.0000000003512 70.0
HFD1_k127_643541_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 1.651e-221 690.0
HFD1_k127_643541_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 4.333e-201 628.0
HFD1_k127_643541_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 569.0
HFD1_k127_643541_3 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009157 543.0
HFD1_k127_643541_4 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 373.0
HFD1_k127_643541_5 Modulates RecA activity K03565 - - 0.000000000000000000000000000000000000000000000000005974 185.0
HFD1_k127_643541_6 Protein of unknown function (DUF465) K09794 - - 0.0000000000000000000000000000000005825 134.0
HFD1_k127_643541_7 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.000000000000000004824 86.0
HFD1_k127_6448919_0 TonB dependent receptor K02014 - - 2.391e-194 629.0
HFD1_k127_6448919_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 336.0
HFD1_k127_6451535_0 chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 400.0
HFD1_k127_6451535_1 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000000000000000000006753 212.0
HFD1_k127_6451535_2 chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000001364 213.0
HFD1_k127_6451535_3 chemotaxis, protein K03406 - - 0.00000000000000000000000000202 118.0
HFD1_k127_6457233_0 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 402.0
HFD1_k127_6457233_1 Bacterial protein of unknown function (DUF934) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000614 245.0
HFD1_k127_6457233_2 Sulfite reductase K00381,K00392 - 1.8.1.2,1.8.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000006351 237.0
HFD1_k127_645726_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 0.0 1176.0
HFD1_k127_645726_1 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009848 515.0
HFD1_k127_645726_2 abc-type tungstate transport system, permease component - - - 0.000000000000000000000000000000000000000000000002751 182.0
HFD1_k127_645726_3 Molybdate K02018 - - 0.000000000000000000000000000000001374 139.0
HFD1_k127_645726_5 MOSC domain - - - 0.0000002343 60.0
HFD1_k127_6457813_0 Transposase DDE domain group 1 - - - 0.000000000000000000000000000000000191 151.0
HFD1_k127_6465900_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 326.0
HFD1_k127_6465900_1 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 291.0
HFD1_k127_6465900_2 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000000007836 166.0
HFD1_k127_6466081_0 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 443.0
HFD1_k127_6466081_1 Predicted metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007156 305.0
HFD1_k127_6466081_2 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 286.0
HFD1_k127_6466081_3 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003443 274.0
HFD1_k127_6466081_4 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000138 254.0
HFD1_k127_6466081_5 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000005682 216.0
HFD1_k127_6466081_6 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000000000000000000000000000000000001722 139.0
HFD1_k127_6466081_7 - - - - 0.0000002911 56.0
HFD1_k127_6471322_0 Peptidase M61 - - - 1.346e-263 822.0
HFD1_k127_6471322_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008234 351.0
HFD1_k127_6471322_2 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 331.0
HFD1_k127_6471322_3 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001736 261.0
HFD1_k127_6473732_0 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 526.0
HFD1_k127_6473732_1 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 416.0
HFD1_k127_6473732_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000005144 104.0
HFD1_k127_6476231_0 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 598.0
HFD1_k127_6476567_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 5.277e-248 770.0
HFD1_k127_6476567_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000348 211.0
HFD1_k127_6476567_2 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000003361 168.0
HFD1_k127_6482760_0 required for the transposition of insertion element IS2404 - - - 0.0000000000000000000000000000000000000000000000000000001018 208.0
HFD1_k127_649000_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0 1191.0
HFD1_k127_6491394_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 404.0
HFD1_k127_6491394_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 347.0
HFD1_k127_6491394_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000227 279.0
HFD1_k127_6492181_0 ABC transporter K06158 - - 5.559e-313 972.0
HFD1_k127_6492181_1 PFAM regulatory protein, MarR - - - 0.00000000000000000000000000000000000000000008851 162.0
HFD1_k127_6497303_0 FtsX-like permease family K02004 - - 0.0 1137.0
HFD1_k127_6497303_1 Belongs to the ParA family K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000698 482.0
HFD1_k127_6497303_2 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 432.0
HFD1_k127_6497303_3 PFAM CoA-binding domain protein K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 354.0
HFD1_k127_6497303_4 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 314.0
HFD1_k127_6497303_5 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001482 284.0
HFD1_k127_6497303_6 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.00000000000000000000000000000000000008333 144.0
HFD1_k127_6525587_0 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 484.0
HFD1_k127_6525587_1 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 438.0
HFD1_k127_6525587_10 - - - - 0.0007031 47.0
HFD1_k127_6525587_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 412.0
HFD1_k127_6525587_3 peptidase M48, Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009932 422.0
HFD1_k127_6525587_5 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 302.0
HFD1_k127_6525587_6 Strictosidine synthase K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008502 292.0
HFD1_k127_6525587_7 Phosphotransferase system, mannose fructose-specific component IIA K02821 - 2.7.1.194 0.000000000000000000000000000000000000000000000000000000000000000004269 229.0
HFD1_k127_6525587_8 TIGRFAM phosphocarrier, HPr family K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000001974 120.0
HFD1_k127_6525587_9 Predicted membrane protein (DUF2061) - - - 0.000000000000000006325 85.0
HFD1_k127_652604_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 5.99e-270 838.0
HFD1_k127_652604_1 HAD-superfamily hydrolase, subfamily IB (PSPase-like) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 366.0
HFD1_k127_652604_2 Belongs to the DnaA family K10763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 312.0
HFD1_k127_652604_3 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004242 257.0
HFD1_k127_652604_4 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000005886 145.0
HFD1_k127_6532043_0 Ftsk_gamma K03466 - - 1.58e-282 883.0
HFD1_k127_6532043_1 Amidohydrolase family K01465 - 3.5.2.3 2.453e-248 771.0
HFD1_k127_6532043_2 Fatty acid desaturase K00507 - 1.14.19.1 1.637e-214 670.0
HFD1_k127_6532043_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405 568.0
HFD1_k127_6532043_4 Transcriptional regulator, Crp Fnr family K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 410.0
HFD1_k127_6532043_5 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 323.0
HFD1_k127_6532043_6 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009425 284.0
HFD1_k127_6532043_7 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000000000000000002358 153.0
HFD1_k127_6532043_8 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000000000000001612 111.0
HFD1_k127_6540898_0 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 586.0
HFD1_k127_6540898_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008309 529.0
HFD1_k127_6540898_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 362.0
HFD1_k127_6540898_3 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 314.0
HFD1_k127_6540898_4 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000000000000000000000000000000000000000000000000000002321 212.0
HFD1_k127_6540898_5 Domain of unknown function (DUF4845) - - - 0.00000000000000000000000000000000000000004453 155.0
HFD1_k127_6545597_0 Insulinase (Peptidase family M16) K07263 - - 0.0 1150.0
HFD1_k127_6545597_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 586.0
HFD1_k127_6545597_2 Lytic murein transglycosylase B K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 471.0
HFD1_k127_6545597_3 HlyD family K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 371.0
HFD1_k127_6545597_4 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 351.0
HFD1_k127_6545597_5 outer membrane lipoprotein K06077 - - 0.00000000000000000000000000000000000000000000000000000001045 202.0
HFD1_k127_6545597_6 Histone family protein nucleoid-structuring protein H-NS K03746 - - 0.000000000000000000000000000000000000000000000008424 173.0
HFD1_k127_6552166_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 547.0
HFD1_k127_6552166_1 acetylornithine K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006667 467.0
HFD1_k127_6560135_0 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 441.0
HFD1_k127_6560135_1 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 327.0
HFD1_k127_6560135_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000002578 141.0
HFD1_k127_6562880_0 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 5.549e-240 755.0
HFD1_k127_6562880_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 359.0
HFD1_k127_6562880_2 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000000000000000000000000000000001202 196.0
HFD1_k127_6562880_3 YqcI/YcgG family K09190 - - 0.000000009039 64.0
HFD1_k127_6567792_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 3.151e-198 621.0
HFD1_k127_6567792_1 Transcriptional regulator - - - 0.000000000000000000000000000000000002226 148.0
HFD1_k127_6567792_2 Peptidase family C25 - - - 0.000000000000000000002142 98.0
HFD1_k127_6567792_3 - - - - 0.00000000000001947 85.0
HFD1_k127_6574808_0 AraC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005369 259.0
HFD1_k127_6574808_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007757 262.0
HFD1_k127_6574808_2 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000003183 124.0
HFD1_k127_6574808_3 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000008575 115.0
HFD1_k127_6574808_4 helix_turn_helix, arabinose operon control protein K04033 - - 0.00000000001762 75.0
HFD1_k127_6577667_0 Aminotransferase class I and II K00832 - 2.6.1.57 3.188e-207 646.0
HFD1_k127_6577667_1 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001138 273.0
HFD1_k127_6577667_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003357 274.0
HFD1_k127_6583487_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11745,K11747 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 565.0
HFD1_k127_6583487_1 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 391.0
HFD1_k127_6583487_2 Domain of unknown function (DUF2383) - - - 0.000000000000000000000000000000000000000000000000001537 189.0
HFD1_k127_6583487_3 PFAM Ribonuclease BN-like family K07058 - - 0.0000000000000000000000000000000000000000007101 165.0
HFD1_k127_6583487_4 Domain of unknown function (DUF4142) K08995 - - 0.000000000000000000000000000001244 130.0
HFD1_k127_6583487_5 OmpA-like transmembrane domain - - - 0.0000000000000000000000000001065 124.0
HFD1_k127_659506_0 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001796 285.0
HFD1_k127_659506_1 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000000000000000000002629 257.0
HFD1_k127_659506_2 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000003057 156.0
HFD1_k127_659506_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00006949 48.0
HFD1_k127_660441_0 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 1.231e-207 660.0
HFD1_k127_660441_1 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 413.0
HFD1_k127_660441_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 385.0
HFD1_k127_660441_3 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 332.0
HFD1_k127_660441_4 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000008394 104.0
HFD1_k127_6623854_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007823 612.0
HFD1_k127_6630790_0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000417 296.0
HFD1_k127_6630790_1 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001389 245.0
HFD1_k127_6630790_3 Histidine triad (Hit) protein K02503 - - 0.00000000000000000000000000000003541 128.0
HFD1_k127_6630790_5 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.00000000006576 63.0
HFD1_k127_663662_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1204.0
HFD1_k127_6638019_0 Phage tail sheath C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 439.0
HFD1_k127_6641021_0 chemotaxis K03406,K03776,K05875 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 396.0
HFD1_k127_6641021_1 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001516 261.0
HFD1_k127_6641021_2 Domain of unknown function (DUF4280) - - - 0.0000000000000000000000000000000000000000000005932 169.0
HFD1_k127_6641021_3 - - - - 0.0000000000000000004349 89.0
HFD1_k127_6641021_4 OmpA family - - - 0.000000000006771 73.0
HFD1_k127_6645284_0 Binding-protein-dependent transport system inner membrane component K10003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 356.0
HFD1_k127_6645284_1 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K10002 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 339.0
HFD1_k127_6645284_2 ABC-type polar amino acid transport system, ATPase component K10004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007748 292.0
HFD1_k127_6645284_3 PFAM porin Gram-negative type - - - 0.0000000000005495 71.0
HFD1_k127_6648230_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 3.763e-230 725.0
HFD1_k127_6648230_1 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000021 246.0
HFD1_k127_6648230_2 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000002668 72.0
HFD1_k127_6651728_0 PFAM Citrate transporter - - - 1.131e-209 662.0
HFD1_k127_6651728_1 Patatin phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 543.0
HFD1_k127_6651728_2 alcohol dehydrogenase K19745 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 490.0
HFD1_k127_6651728_3 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 479.0
HFD1_k127_6651728_4 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 457.0
HFD1_k127_6651728_5 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 417.0
HFD1_k127_6651728_6 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 392.0
HFD1_k127_6651728_7 PFAM peptidylprolyl isomerase FKBP-type K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000002191 201.0
HFD1_k127_6651728_8 Protein of unknown function (DUF3617) - - - 0.0000000000000000000000000000000001647 139.0
HFD1_k127_6651728_9 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798,K13525 - - 0.00000001079 58.0
HFD1_k127_6652101_0 Peptidase C39 family K13409 - - 0.0 1067.0
HFD1_k127_6652101_1 HlyD family secretion protein K13408 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 491.0
HFD1_k127_6652101_2 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 292.0
HFD1_k127_6652101_3 TIGRFAM type I secretion outer membrane protein, TolC family K12543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008432 260.0
HFD1_k127_6652101_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000004753 192.0
HFD1_k127_6652157_0 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 3.412e-245 761.0
HFD1_k127_6652157_1 diguanylate cyclase K21019 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009378 410.0
HFD1_k127_6652157_2 Large family of predicted nucleotide-binding domains K07175 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 336.0
HFD1_k127_6652157_3 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000231 242.0
HFD1_k127_6654663_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K19969 - 4.2.3.152,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 448.0
HFD1_k127_6654663_1 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000008236 242.0
HFD1_k127_6654663_2 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000003716 149.0
HFD1_k127_6654663_3 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000009223 134.0
HFD1_k127_6654663_4 - - - - 0.0000000000000000000000000000004017 136.0
HFD1_k127_6685811_0 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005557 505.0
HFD1_k127_6685811_1 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 450.0
HFD1_k127_6685811_10 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000001159 168.0
HFD1_k127_6685811_11 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000001827 102.0
HFD1_k127_6685811_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 427.0
HFD1_k127_6685811_3 GDSL-like Lipase/Acylhydrolase family K11018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 391.0
HFD1_k127_6685811_4 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 365.0
HFD1_k127_6685811_5 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 329.0
HFD1_k127_6685811_6 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 307.0
HFD1_k127_6685811_7 dNA-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 288.0
HFD1_k127_6685811_8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000003014 238.0
HFD1_k127_6685811_9 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000001607 176.0
HFD1_k127_6688487_0 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000913 401.0
HFD1_k127_6688487_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000002844 263.0
HFD1_k127_6688487_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000005026 175.0
HFD1_k127_6688487_3 ThiS family K03154 - - 0.0000000000000000004149 89.0
HFD1_k127_670163_0 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 1.202e-205 647.0
HFD1_k127_670163_1 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000798 336.0
HFD1_k127_6703109_0 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 4.211e-234 735.0
HFD1_k127_6703109_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001129 271.0
HFD1_k127_6703109_2 - - - - 0.000000000000000004985 88.0
HFD1_k127_6705018_0 Protein of unknown function (DUF815) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 466.0
HFD1_k127_6705018_1 enoyl-CoA hydratase isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002928 279.0
HFD1_k127_6705018_2 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000001471 263.0
HFD1_k127_6705018_3 enoyl-CoA hydratase isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000005325 241.0
HFD1_k127_6705121_0 aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 580.0
HFD1_k127_6705121_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006278 471.0
HFD1_k127_6705121_2 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002815 273.0
HFD1_k127_6705121_3 NMT1-like family - - - 0.0000000000000000000000000008242 116.0
HFD1_k127_6705591_0 PFAM Major facilitator superfamily K02575 - - 3.769e-227 711.0
HFD1_k127_6705591_1 UbiH UbiF VisC COQ6 family K03185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 606.0
HFD1_k127_6705591_2 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 545.0
HFD1_k127_6705591_3 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362,K05297 - 1.18.1.1,1.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006637 432.0
HFD1_k127_6705591_4 ANTAR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 359.0
HFD1_k127_6705591_5 - - - - 0.0000000000000000000000000000005352 129.0
HFD1_k127_6705591_6 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.0000000001956 64.0
HFD1_k127_6708256_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 578.0
HFD1_k127_6708256_1 DEAD DEAH box helicase K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001411 246.0
HFD1_k127_6708256_2 Calcineurin-like phosphoesterase K06953 - - 0.0000000000000000000000000000000000000000000000000004529 192.0
HFD1_k127_6709038_0 PFAM AMP-dependent synthetase and ligase K00666,K01897 - 6.2.1.3 1.855e-279 873.0
HFD1_k127_6709038_1 Amidohydrolase K22213 - 4.1.1.52 3.548e-207 647.0
HFD1_k127_6709038_2 fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 459.0
HFD1_k127_6709038_3 regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000000000000000406 226.0
HFD1_k127_6709038_4 PFAM beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000001425 233.0
HFD1_k127_6709038_5 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000756 194.0
HFD1_k127_6709038_6 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000009217 124.0
HFD1_k127_671537_0 formamidopyrimidine-DNA glycosylase K05522 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 349.0
HFD1_k127_671537_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 332.0
HFD1_k127_671537_2 TPM domain - - - 0.0000000000000000000000000000000000000000000000000000001449 202.0
HFD1_k127_671537_3 TPM domain K06872 - - 0.0000001528 55.0
HFD1_k127_6727956_0 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0 1154.0
HFD1_k127_6727956_1 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 532.0
HFD1_k127_6727956_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005869 255.0
HFD1_k127_6727956_3 Ribosome-associated heat shock protein K04762 - - 0.000000000000000000000000000000000000000000000000000002428 193.0
HFD1_k127_6727956_4 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000001564 177.0
HFD1_k127_6727956_5 - - - - 0.0001975 48.0
HFD1_k127_6730435_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000001897 195.0
HFD1_k127_6730435_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000002855 182.0
HFD1_k127_6731008_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 9.241e-202 635.0
HFD1_k127_6731008_1 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 440.0
HFD1_k127_6731010_0 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 418.0
HFD1_k127_6731010_1 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 345.0
HFD1_k127_6731010_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006838 338.0
HFD1_k127_6731010_3 Belongs to the UPF0324 family - - - 0.000000000000000000000000000000000000000000000000000000000000000002835 242.0
HFD1_k127_6731010_4 Protein of unknown function, DUF599 - - - 0.000000000000000000000000000000000000000000000000000000002275 206.0
HFD1_k127_6731010_5 NMT1-like family K15553 - - 0.0000000000000000000000000000000000000000000000000002912 189.0
HFD1_k127_6731010_6 Protein of unknown function (DUF971) - - - 0.0000000000007256 72.0
HFD1_k127_673332_0 ABC transporter K06147 - - 4.776e-213 679.0
HFD1_k127_673332_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 597.0
HFD1_k127_673332_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 557.0
HFD1_k127_673332_3 ABC transporter K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 329.0
HFD1_k127_673332_4 Thioesterase superfamily K10806 - - 0.00000000000000000000000000000000000000000000000000000000000000000002556 234.0
HFD1_k127_673332_5 17 kDa surface antigen - - - 0.000000000000000000000003927 108.0
HFD1_k127_673332_6 Belongs to the transcriptional regulatory Fis family K03557 - - 0.0000000000003063 69.0
HFD1_k127_6741110_0 PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 320.0
HFD1_k127_6741110_1 Histidine kinase K05962 - 2.7.13.1 0.00000000000000000000000000000000000002028 156.0
HFD1_k127_6742369_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 3.003e-195 624.0
HFD1_k127_6742369_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 488.0
HFD1_k127_6742369_2 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000000000000000000000000000000000000000001308 180.0
HFD1_k127_6742369_3 Metal-dependent hydrolase K07044 - - 0.00000000000000001546 84.0
HFD1_k127_6743074_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 7.201e-238 743.0
HFD1_k127_6743074_1 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 504.0
HFD1_k127_6743074_2 KR domain K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000001082 246.0
HFD1_k127_6747637_0 leucine-zipper of insertion element IS481 - - - 0.0000000000000001281 93.0
HFD1_k127_6747637_1 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000004758 79.0
HFD1_k127_676021_0 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 3.25e-210 658.0
HFD1_k127_676021_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 504.0
HFD1_k127_676021_2 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000565 261.0
HFD1_k127_676021_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000212 218.0
HFD1_k127_6761797_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1745.0
HFD1_k127_6763746_0 Peptidase family S49 K04773 - - 5.462e-240 756.0
HFD1_k127_6763746_1 CoA-transferase family III K07749,K14471,K14472 - 2.8.3.16,2.8.3.22 1.627e-218 683.0
HFD1_k127_6763746_2 Mota tolq exbb proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 355.0
HFD1_k127_6763746_3 Belongs to the UPF0502 family K09915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 308.0
HFD1_k127_6763746_4 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000000000000000000000000000000000000000000000002386 203.0
HFD1_k127_6763746_5 ImpA, N-terminal, type VI secretion system K11902 - - 0.0000000000000000000000000000000000000000000539 164.0
HFD1_k127_6763746_6 - - - - 0.00000000000000000000000000000000005177 135.0
HFD1_k127_6763746_7 TIGRFAM TonB family protein K03832 - - 0.00000000000000000000000000009937 125.0
HFD1_k127_6763746_8 Acetyl-coenzyme A transporter 1 - - - 0.00000000000000001957 84.0
HFD1_k127_6763746_9 Fe-S protein K06938 - - 0.000000384 58.0
HFD1_k127_6769371_0 protein involved in exopolysaccharide biosynthesis K20998 - - 2.412e-251 791.0
HFD1_k127_6769371_1 Glycosyl transferase, group 1 K13658,K20999 - 2.4.1.251 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 410.0
HFD1_k127_6769371_2 Polysaccharide biosynthesis/export protein K20987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 317.0
HFD1_k127_6769371_3 Glycosyltransferase like family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000001057 229.0
HFD1_k127_6769804_0 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 615.0
HFD1_k127_6769804_1 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 321.0
HFD1_k127_6769804_2 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000003068 131.0
HFD1_k127_6779776_0 COG0542 ATPases with chaperone activity, ATP-binding subunit K11907 - - 2.84e-213 671.0
HFD1_k127_6779776_1 Type VI secretion, TssG K11895 - - 0.000000000000000000000000000000000000000000000000000000000001732 211.0
HFD1_k127_6786257_0 Belongs to the DEAD box helicase family K05591 GO:0000339,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003729,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006412,GO:0006413,GO:0006518,GO:0006725,GO:0006807,GO:0008026,GO:0008135,GO:0008150,GO:0008152,GO:0008186,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0010501,GO:0016070,GO:0016281,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0042623,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0060255,GO:0065007,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 3.6.4.13 3.212e-247 769.0
HFD1_k127_6786257_1 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 435.0
HFD1_k127_6786257_2 Domain of unknown function (DUF3362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 409.0
HFD1_k127_6802094_0 Four helix bundle sensory module for signal transduction K03406,K05874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000711 494.0
HFD1_k127_6802094_1 Cys/Met metabolism PLP-dependent enzyme K01760 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 288.0
HFD1_k127_6839517_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 1.951e-253 785.0
HFD1_k127_6839517_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 1.844e-202 635.0
HFD1_k127_6839517_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 532.0
HFD1_k127_6839517_3 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 429.0
HFD1_k127_6839517_4 Tetratricopeptide repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 331.0
HFD1_k127_6839517_5 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000000000000000000009443 164.0
HFD1_k127_6843877_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 5.722e-247 770.0
HFD1_k127_6843877_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000004853 227.0
HFD1_k127_6843877_2 Belongs to the P(II) protein family K04752 - - 0.00000000000000000000000000000000000000000000000000000000000004984 216.0
HFD1_k127_6843877_3 Ammonium Transporter K03320 - - 0.00000000000000000000000000000000002814 137.0
HFD1_k127_6844704_0 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.0 1111.0
HFD1_k127_684744_0 Type IV pili methyl-accepting chemotaxis transducer N-term K02660 - - 0.0 1153.0
HFD1_k127_684744_1 CheW-like domain K02659 - - 0.000000000000000000000000000000000000000000000000000004607 192.0
HFD1_k127_684744_2 Signal transducing histidine kinase, homodimeric domain K02487,K06596 - - 0.000000000000000000000000002977 112.0
HFD1_k127_6864754_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 531.0
HFD1_k127_6864754_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 431.0
HFD1_k127_6871219_0 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 587.0
HFD1_k127_6871219_1 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005676 479.0
HFD1_k127_6871219_2 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.00000000000000000000000000000000000000000000000000000000307 210.0
HFD1_k127_6871219_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K13775 - - 0.00000000003904 65.0
HFD1_k127_6871284_0 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000716 544.0
HFD1_k127_6871284_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 434.0
HFD1_k127_6871284_2 PFAM MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006687 258.0
HFD1_k127_6871284_3 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000000000000112 242.0
HFD1_k127_6871284_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.0000000000000000000000000000000000000000000000000000000000000000001019 236.0
HFD1_k127_6882695_0 GTP-binding protein K06207 - - 0.0 1161.0
HFD1_k127_6882695_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 359.0
HFD1_k127_6882695_2 enoyl-CoA hydratase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000005907 259.0
HFD1_k127_6904457_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 3.418e-223 705.0
HFD1_k127_6904457_1 Protein of unknown function (DUF2804) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 484.0
HFD1_k127_6904457_2 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 338.0
HFD1_k127_6904457_3 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000005702 117.0
HFD1_k127_6917464_0 MltA specific insert domain K08304 - - 5.715e-195 616.0
HFD1_k127_6917464_1 Site-specific recombinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 378.0
HFD1_k127_6917464_2 Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide K01725 - 4.2.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002567 274.0
HFD1_k127_6917464_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005612 271.0
HFD1_k127_6917464_4 Protein of unknown function (DUF1348) - - - 0.00000000000000000000000000000000000000000000000000000007307 198.0
HFD1_k127_6917464_5 - - - - 0.000003286 52.0
HFD1_k127_6924201_0 UPF0761 membrane protein K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 615.0
HFD1_k127_6924201_1 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003613 269.0
HFD1_k127_6924201_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000007614 196.0
HFD1_k127_6924201_3 Predicted membrane protein (DUF2069) - - - 0.0000000000000000000002723 112.0
HFD1_k127_6925458_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 413.0
HFD1_k127_6925458_1 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000001078 188.0
HFD1_k127_6925458_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000001526 191.0
HFD1_k127_6925576_0 Exonuclease C-terminal K01141 - 3.1.11.1 2.282e-249 775.0
HFD1_k127_6925576_1 WLM domain K07043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002779 244.0
HFD1_k127_6925576_2 nucleotidyltransferase activity K18236 - - 0.000000001061 64.0
HFD1_k127_6925576_3 Responsible for synthesis of pseudouridine from uracil K06177 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.28,5.4.99.29 0.000007943 48.0
HFD1_k127_6935217_0 Major facilitator superfamily K05939 - 2.3.1.40,6.2.1.20 4.124e-221 691.0
HFD1_k127_6935217_1 Uncharacterized protein conserved in bacteria (DUF2145) - - - 0.00000000000000000000000000000000000000000000000005371 180.0
HFD1_k127_6958280_0 Domain of unknown function (DUF5117) - - - 3.958e-258 826.0
HFD1_k127_6958280_1 HELICc2 K03722 - 3.6.4.12 3.816e-232 736.0
HFD1_k127_6958280_2 mannitol 2-dehydrogenase activity - - - 3.852e-194 621.0
HFD1_k127_6958280_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006777 466.0
HFD1_k127_6958280_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 396.0
HFD1_k127_6958280_5 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000004856 130.0
HFD1_k127_6962253_0 Double sensory domain of two-component sensor kinase - - - 1.417e-203 638.0
HFD1_k127_6962253_1 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 477.0
HFD1_k127_6962253_2 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 328.0
HFD1_k127_6962253_3 NAD-dependent epimerase dehydratase K07118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 319.0
HFD1_k127_6962253_4 Histidine kinase K07675 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000009647 259.0
HFD1_k127_6962253_5 PFAM Thioredoxin K00384 - 1.8.1.9 0.000000000000000000000000005396 119.0
HFD1_k127_6964913_0 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 506.0
HFD1_k127_6964913_1 Belongs to the GST superfamily K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 348.0
HFD1_k127_6964913_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 302.0
HFD1_k127_6964913_3 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.000003476 48.0
HFD1_k127_6974991_0 Lipid A biosynthesis acyltransferase K02517,K12974 - 2.3.1.241,2.3.1.242 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007117 482.0
HFD1_k127_6974991_1 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 417.0
HFD1_k127_6974991_2 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000006271 198.0
HFD1_k127_6975915_0 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - 3.21e-247 770.0
HFD1_k127_6975915_1 PFAM DsrE DsrF-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 312.0
HFD1_k127_6975915_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01502 - 3.5.5.7 0.000000000000000000000000000000000000000004788 156.0
HFD1_k127_6975915_3 - - - - 0.00000000000000000000000000000000002521 140.0
HFD1_k127_6976254_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 6.023e-219 687.0
HFD1_k127_6976254_1 Fatty acid hydroxylase superfamily - - - 0.00000000000000000002544 96.0
HFD1_k127_6977593_0 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 299.0
HFD1_k127_6977593_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003939 268.0
HFD1_k127_6977593_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18303 - - 0.0000000000000000000000000000000000002847 145.0
HFD1_k127_6982366_0 lytic transglycosylase K08307 - - 1.27e-198 631.0
HFD1_k127_6982366_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 327.0
HFD1_k127_6982366_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000000000000000000000000001607 203.0
HFD1_k127_6982366_3 membrane - - - 0.00000000000000000000000000000000000000005547 155.0
HFD1_k127_6982366_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000006814 60.0
HFD1_k127_6984324_0 Diguanylate cyclase K21023 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 414.0
HFD1_k127_6984324_1 Protein of unknown function (DUF3567) - - - 0.00000000000000000000000000000000000002592 147.0
HFD1_k127_6987140_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 3.521e-288 887.0
HFD1_k127_6987140_1 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000002783 60.0
HFD1_k127_7000338_0 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 554.0
HFD1_k127_7000338_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 329.0
HFD1_k127_7000338_2 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 318.0
HFD1_k127_7000338_3 ResB-like family K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 303.0
HFD1_k127_7000338_4 Protein of unknown function, DUF481 K07283 - - 0.000000000000000000000000000000000000000000003581 175.0
HFD1_k127_7000338_5 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000003099 79.0
HFD1_k127_7002045_0 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 496.0
HFD1_k127_7002045_1 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004892 376.0
HFD1_k127_7003957_0 OmpA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 475.0
HFD1_k127_7003957_1 Domain of unknown function DUF11 - - - 0.0000000000000000000000000000000000000000000000000003518 188.0
HFD1_k127_7031309_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 4.847e-273 849.0
HFD1_k127_7031309_1 Histidine kinase - - - 0.000000000000000000000004243 110.0
HFD1_k127_7039462_0 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 452.0
HFD1_k127_7039462_1 Peptidase dimerisation domain K13049 - - 0.000000000000000000000000000000000000000000000000000001783 196.0
HFD1_k127_7042087_0 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009587 476.0
HFD1_k127_7042087_1 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000001613 207.0
HFD1_k127_7042087_2 KR domain - - - 0.00000000000000000000000000000000000339 140.0
HFD1_k127_7047453_0 Transport of potassium into the cell K03549 - - 0.0 1028.0
HFD1_k127_7047453_1 C-terminal, D2-small domain, of ClpB protein K11907 - - 3.451e-236 735.0
HFD1_k127_7047453_2 Regulator K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008691 391.0
HFD1_k127_7047453_3 Integral membrane sensor signal transduction histidine kinase K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 349.0
HFD1_k127_7047453_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001101 249.0
HFD1_k127_7052083_0 Transcriptional regulatory protein, C terminal K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000307 269.0
HFD1_k127_7052083_1 FecR protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003268 266.0
HFD1_k127_7052083_2 ATPases associated with a variety of cellular activities K06159,K06160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003831 252.0
HFD1_k127_705302_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 2.999e-235 734.0
HFD1_k127_705302_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 540.0
HFD1_k127_705302_2 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 370.0
HFD1_k127_705302_3 Protein of unknown function (DUF808) K09781 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 327.0
HFD1_k127_705302_4 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002375 258.0
HFD1_k127_705302_5 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000000000000000000000000009822 197.0
HFD1_k127_7055203_0 membrane-associated Zn-dependent proteases 1 K16922 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 527.0
HFD1_k127_7055203_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 373.0
HFD1_k127_7070173_0 This family consists of a number of uncharacterised bacterial proteins. The function of this family is K11900 - - 1.484e-294 908.0
HFD1_k127_7070173_1 Major facilitator Superfamily K08218 - - 3.851e-266 825.0
HFD1_k127_7070173_10 Type VI secretion system effector, Hcp K11903 - - 0.00000000000000000000000000000000000000000000004694 175.0
HFD1_k127_7070173_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000861 531.0
HFD1_k127_7070173_3 Type VI secretion protein K11896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 393.0
HFD1_k127_7070173_4 Virulence protein SciE type K11898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 354.0
HFD1_k127_7070173_5 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000944 285.0
HFD1_k127_7070173_6 Type VI secretion system effector, Hcp K06887,K11903 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004725 240.0
HFD1_k127_7070173_7 peptidase M48, Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000001422 222.0
HFD1_k127_7070173_8 ImpA, N-terminal, type VI secretion system K11902 - - 0.000000000000000000000000000000000000000000000000000000000006661 220.0
HFD1_k127_7070173_9 TIGRFAM type VI secretion system lysozyme-related protein K11897 - - 0.00000000000000000000000000000000000000000000000000000000006621 209.0
HFD1_k127_7081894_0 the major facilitator superfamily - - - 4.419e-209 655.0
HFD1_k127_7081894_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.027e-202 637.0
HFD1_k127_7081894_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 411.0
HFD1_k127_7085089_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 403.0
HFD1_k127_7085089_1 synthesis repressor, PhaR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001266 280.0
HFD1_k127_7091728_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 430.0
HFD1_k127_7091728_1 Protein of unknown function - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 292.0
HFD1_k127_7092994_0 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009921 401.0
HFD1_k127_7092994_1 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 380.0
HFD1_k127_7092994_2 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 318.0
HFD1_k127_7092994_3 Ethanolamine ammonia-lyase light chain (EutC) K03736 - 4.3.1.7 0.0000000000000000000000000000000000000000000000000004446 189.0
HFD1_k127_7092994_4 - - - - 0.0000000000000000000000000000007855 131.0
HFD1_k127_7096060_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 525.0
HFD1_k127_7096060_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 382.0
HFD1_k127_7096060_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 320.0
HFD1_k127_7096060_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007631 284.0
HFD1_k127_7096236_0 Bacterial extracellular solute-binding protein K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 551.0
HFD1_k127_7096236_1 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 421.0
HFD1_k127_7096236_2 Bacterial extracellular solute-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 376.0
HFD1_k127_7096236_3 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.000000000000000000000000000000000000000000000002062 182.0
HFD1_k127_7096236_4 Bacterial extracellular solute-binding protein K02048 - - 0.000000000000000000000000000122 115.0
HFD1_k127_7096236_5 sulfate ABC transporter K02046,K15496 - - 0.000000007438 57.0
HFD1_k127_7111888_0 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009228 557.0
HFD1_k127_7111888_1 epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 433.0
HFD1_k127_7111888_2 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 327.0
HFD1_k127_7111888_3 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000545 226.0
HFD1_k127_7111888_4 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000004586 203.0
HFD1_k127_7114752_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 559.0
HFD1_k127_7114752_1 Major facilitator superfamily K08224 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 518.0
HFD1_k127_7114752_2 histidine kinase HAMP region domain protein K05962 - 2.7.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 399.0
HFD1_k127_7114752_3 Phosphate acetyl/butaryl transferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008295 373.0
HFD1_k127_7114752_4 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009677 342.0
HFD1_k127_7114752_5 cytochrome c biogenesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 306.0
HFD1_k127_7114752_6 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.00000000000000000000000000000000000000000001854 168.0
HFD1_k127_7114752_7 Protein of unknown function (DUF3606) - - - 0.0000003904 61.0
HFD1_k127_712879_0 MMPL family K18138,K18902 - - 1.552e-293 909.0
HFD1_k127_712879_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 392.0
HFD1_k127_7131900_0 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 526.0
HFD1_k127_7131900_1 PQ loop repeat K15383 - - 0.0000000000000000000000000003881 117.0
HFD1_k127_7137150_0 Flavin-binding monooxygenase-like K07222 - - 1.285e-218 686.0
HFD1_k127_7137150_1 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.00000000000000000000000003409 115.0
HFD1_k127_7137150_2 - - - - 0.000000000000000000000002762 108.0
HFD1_k127_7153918_0 DDE_Tnp_1-associated - - - 0.0000000000000000000000000000000000000000000000000000000007231 217.0
HFD1_k127_7153918_1 transposase activity - - - 0.0000000001381 73.0
HFD1_k127_715421_0 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 616.0
HFD1_k127_715421_1 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 351.0
HFD1_k127_715421_2 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001073 264.0
HFD1_k127_715421_3 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000005005 164.0
HFD1_k127_7163585_0 histidine kinase A domain protein - - - 2.219e-232 743.0
HFD1_k127_7163585_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 400.0
HFD1_k127_7163585_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 331.0
HFD1_k127_7163585_3 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 294.0
HFD1_k127_716804_0 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017 476.0
HFD1_k127_716804_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003405 261.0
HFD1_k127_716804_2 - - - - 0.0000004209 55.0
HFD1_k127_7189683_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.743e-241 750.0
HFD1_k127_7189683_1 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 463.0
HFD1_k127_7189683_2 - - - - 0.0000225 54.0
HFD1_k127_719042_0 Protein of unknown function (DUF1800) - - - 3.957e-198 636.0
HFD1_k127_719042_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 601.0
HFD1_k127_719042_10 Protein of unknown function (DUF3485) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000149 240.0
HFD1_k127_719042_11 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000004476 173.0
HFD1_k127_719042_12 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000004888 153.0
HFD1_k127_719042_13 acetyltransferase, isoleucine patch superfamily K03818 - - 0.0000000000000000000000000000000000002288 147.0
HFD1_k127_719042_14 Transposase - - - 0.00000003896 63.0
HFD1_k127_719042_2 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 566.0
HFD1_k127_719042_3 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 505.0
HFD1_k127_719042_4 PFAM glycosyl transferase group 1 K03208 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 486.0
HFD1_k127_719042_5 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 452.0
HFD1_k127_719042_6 polysaccharide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 436.0
HFD1_k127_719042_7 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 405.0
HFD1_k127_719042_8 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 385.0
HFD1_k127_719042_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009015 291.0
HFD1_k127_7196306_0 Protein of unknown function - - - 2.229e-235 748.0
HFD1_k127_7201314_0 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009504 484.0
HFD1_k127_7201314_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 365.0
HFD1_k127_7201314_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000006934 64.0
HFD1_k127_7216637_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 389.0
HFD1_k127_7216637_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000009804 72.0
HFD1_k127_7229370_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1108.0
HFD1_k127_7229370_1 Dehydrogenase K00382 - 1.8.1.4 5.521e-243 755.0
HFD1_k127_7229370_2 RES - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 308.0
HFD1_k127_7229370_3 Protein of unknown function (DUF2384) - - - 0.000000000000000000000000000000000000000000000000000000000004679 210.0
HFD1_k127_7229370_4 - - - - 0.00000001045 59.0
HFD1_k127_7233935_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 3.942e-265 820.0
HFD1_k127_7233935_1 Protein of unknown function (DUF1631) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 448.0
HFD1_k127_7233935_2 Cytochrome C1 K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 391.0
HFD1_k127_7233935_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 351.0
HFD1_k127_7233935_4 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000000000000000000000000004426 233.0
HFD1_k127_7236389_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 458.0
HFD1_k127_7236389_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004463 276.0
HFD1_k127_7236389_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000006605 102.0
HFD1_k127_7242090_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 6.267e-284 878.0
HFD1_k127_7242090_1 Sugar (and other) transporter K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 576.0
HFD1_k127_7242090_2 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003702 266.0
HFD1_k127_7242090_3 cyclase dehydrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001771 236.0
HFD1_k127_7242090_4 Domain of unknown function (DUF4124) - - - 0.0000000000000000000000000000000000000000000273 168.0
HFD1_k127_7242090_5 Chemotaxis sensory transducer K03406,K05874 - - 0.00000000000000000000001014 103.0
HFD1_k127_7242090_6 Belongs to the UPF0125 (RnfH) family K09801 - - 0.0000000000000000000003779 100.0
HFD1_k127_7257945_0 Amino acid adenylation domain - - - 6.391e-297 934.0
HFD1_k127_7257945_1 Erythromycin esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004586 541.0
HFD1_k127_7257945_2 Amino acid adenylation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 446.0
HFD1_k127_7257945_3 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 293.0
HFD1_k127_7257945_4 Domain of unknown function (DU1801) - - - 0.00000000000000000000006617 104.0
HFD1_k127_7261533_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008741 326.0
HFD1_k127_7261533_1 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006573 286.0
HFD1_k127_7261533_2 Zinc carboxypeptidase - - - 0.000000000000000000000000000000000000000000002622 165.0
HFD1_k127_7261533_3 Ferredoxin - - - 0.0000000000000000000000002604 114.0
HFD1_k127_7267591_0 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 452.0
HFD1_k127_7267591_2 - - - - 0.000000000000000000000000000000000003549 144.0
HFD1_k127_7267591_3 PEP-CTERM motif - - - 0.0003313 51.0
HFD1_k127_7267786_0 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001901 253.0
HFD1_k127_7267786_1 Asparaginase K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000002091 202.0
HFD1_k127_7267786_2 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000000000000000000004368 186.0
HFD1_k127_7268356_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 593.0
HFD1_k127_7268356_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 400.0
HFD1_k127_7268356_10 YCII-related domain - - - 0.000000002142 59.0
HFD1_k127_7268356_2 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007598 394.0
HFD1_k127_7268356_3 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006947 390.0
HFD1_k127_7268356_4 Fatty acid hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 379.0
HFD1_k127_7268356_5 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 304.0
HFD1_k127_7268356_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003244 254.0
HFD1_k127_7268356_7 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000247 251.0
HFD1_k127_7268356_8 PFAM DGPFAETKE family protein - - - 0.00000000000000000000000000000002584 128.0
HFD1_k127_7272397_0 transposition - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 356.0
HFD1_k127_7273522_0 Alcohol dehydrogenase GroES-like domain K12957,K13979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 554.0
HFD1_k127_7273522_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 346.0
HFD1_k127_7273522_2 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006938 273.0
HFD1_k127_7273597_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 546.0
HFD1_k127_7273899_0 Lysine-specific metallo-endopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 374.0
HFD1_k127_7273899_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 348.0
HFD1_k127_7273899_2 - - - - 0.00000000000000000000000000000003909 142.0
HFD1_k127_7273899_3 - - - - 0.0000000000000000000000002984 111.0
HFD1_k127_7280513_0 OpgC protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 440.0
HFD1_k127_7280513_1 PFAM MgtC SapB transporter K07507 - - 0.0000000000000000000000000000000000000000000000000000000000000000005138 231.0
HFD1_k127_7280513_2 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000008182 225.0
HFD1_k127_7280513_3 Ion transport protein - - - 0.00000000000000000000000000000000000000000000001565 177.0
HFD1_k127_7284365_0 May be involved in recombinational repair of damaged DNA K03631 - - 2.212e-272 855.0
HFD1_k127_7284365_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 578.0
HFD1_k127_7284365_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 496.0
HFD1_k127_7284365_3 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 465.0
HFD1_k127_7284365_4 Pfam:HipA_N K07154 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 323.0
HFD1_k127_7284365_5 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000002665 119.0
HFD1_k127_7284365_6 - - - - 0.000000000000001121 84.0
HFD1_k127_7284700_0 2OG-Fe dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 379.0
HFD1_k127_7284700_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008467 245.0
HFD1_k127_7284700_2 TonB-dependent receptor plug K02014 - - 0.0000000000000000000000000000000000000000001641 165.0
HFD1_k127_7284700_3 Protein of unknown function (DUF2946) - - - 0.00000000000000000000001391 106.0
HFD1_k127_7291252_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 346.0
HFD1_k127_7291252_1 diguanylate cyclase K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000931 175.0
HFD1_k127_7291252_2 - - - - 0.00000000000000000000000000000000001411 142.0
HFD1_k127_7291252_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000004616 96.0
HFD1_k127_7296525_0 cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 1.177e-215 678.0
HFD1_k127_7296525_1 Flavin containing amine oxidoreductase K06954 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 495.0
HFD1_k127_7296525_2 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 376.0
HFD1_k127_7307700_0 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 364.0
HFD1_k127_7307700_1 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 355.0
HFD1_k127_7307700_2 Domain of unknown function (DUF4936) - - - 0.0000000000000003822 81.0
HFD1_k127_7307700_3 Belongs to the GcvT family K06980 - - 0.000000000003215 68.0
HFD1_k127_7313348_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 8.926e-246 764.0
HFD1_k127_7313348_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000093 239.0
HFD1_k127_7313348_2 Domain of unknown function (DUF4136) - - - 0.00000000000000000000000000000000000000000000003928 177.0
HFD1_k127_7313348_3 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000001912 126.0
HFD1_k127_7322439_0 GTP-binding signal recognition particle K02404 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 550.0
HFD1_k127_7322439_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 528.0
HFD1_k127_7322439_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 439.0
HFD1_k127_7322439_3 bacterial-type flagellum organization K04562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007601 258.0
HFD1_k127_7322439_4 chemotaxis protein K03406,K05874 - - 0.00000000000000000000000000000000000000000000000001033 189.0
HFD1_k127_7347900_0 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 526.0
HFD1_k127_7347900_1 Glycosyl transferase family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000007971 207.0
HFD1_k127_7357135_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1286.0
HFD1_k127_7357135_1 NIPSNAP - - - 0.0000000000000000000000000000000000000000000000000002056 191.0
HFD1_k127_7357135_2 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000000000000000000000000000002186 181.0
HFD1_k127_7357135_3 - - - - 0.00000000000000000000000000000000008081 134.0
HFD1_k127_7357788_0 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 474.0
HFD1_k127_7357788_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 410.0
HFD1_k127_7357788_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007011 249.0
HFD1_k127_7357788_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000000000000000001265 231.0
HFD1_k127_7357788_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000000000000000007207 219.0
HFD1_k127_7357788_5 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000005379 183.0
HFD1_k127_7357788_6 ATP synthase I chain K02116 - - 0.0000000000000000000000000000000000000004897 154.0
HFD1_k127_7357788_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000000000545 147.0
HFD1_k127_7367967_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 8.52e-267 831.0
HFD1_k127_7367967_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006803 248.0
HFD1_k127_7367967_2 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K14160 - - 0.00000000000000000000000000000000000000000000000000000000000002963 222.0
HFD1_k127_7367967_3 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000003345 106.0
HFD1_k127_7368581_0 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 331.0
HFD1_k127_7368581_1 ThiF family K22132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006195 308.0
HFD1_k127_7368581_2 SMP-30/Gluconolaconase/LRE-like region - - - 0.0000000000000000000000000000000000000000000000000000000001909 218.0
HFD1_k127_7374372_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 291.0
HFD1_k127_7374372_1 Domain of unknown function (DUF4115) K15539 - - 0.0000000000000000000000000000000000000000000003518 178.0
HFD1_k127_7374372_2 Type IV pilus biogenesis stability protein PilW K02656 - - 0.0000000000000000000000001265 106.0
HFD1_k127_738280_0 Circadian clock protein KaiC K08482 - - 8.42e-244 771.0
HFD1_k127_738280_1 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 479.0
HFD1_k127_738280_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008876 494.0
HFD1_k127_738280_3 PFAM Short-chain dehydrogenase reductase SDR K00059,K00076 - 1.1.1.100,1.1.1.159 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 422.0
HFD1_k127_738280_4 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.000000000000000000000000000000000000000000000007481 172.0
HFD1_k127_738280_5 Domain of unknown function (DUF4142) K08995 - - 0.00000000000000000000000000000000000000000001375 171.0
HFD1_k127_738280_6 KaiB K08481 - - 0.000000000000000000000000000000000000000009418 158.0
HFD1_k127_738280_7 - - - - 0.0000000000000000000000000000006956 132.0
HFD1_k127_738280_8 KaiB K08481 - - 0.000000000000000000000000001568 115.0
HFD1_k127_738280_9 SlyX K03745 - - 0.0000000000000000000004425 108.0
HFD1_k127_7383842_0 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 429.0
HFD1_k127_7383842_1 TOBE domain - - - 0.000000000000000000000000006288 111.0
HFD1_k127_7383842_3 Cysteine-rich CWC - - - 0.00000000000005415 74.0
HFD1_k127_7383982_0 ResB-like family K07399 - - 5.804e-196 621.0
HFD1_k127_7383982_1 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 519.0
HFD1_k127_7387287_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 287.0
HFD1_k127_7387287_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000607 283.0
HFD1_k127_7387287_2 COG0604 NADPH quinone reductase and related Zn-dependent - - - 0.000000000000000000000000000000000000000000000000000006557 198.0
HFD1_k127_7393285_0 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K12132 - 2.7.11.1,3.1.3.16 2.799e-218 683.0
HFD1_k127_7393285_1 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009081 382.0
HFD1_k127_7409164_0 TIGRFAM type I secretion system ATPase K12541 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 608.0
HFD1_k127_7409164_1 Nudix hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 345.0
HFD1_k127_7409164_2 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000008239 203.0
HFD1_k127_7409164_3 Chorismate lyase K03181 - 4.1.3.40 0.000000000000000001732 98.0
HFD1_k127_7411440_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 533.0
HFD1_k127_7411440_1 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 302.0
HFD1_k127_7411440_2 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000001147 169.0
HFD1_k127_7411440_3 Glycosyl transferase WecB/TagA/CpsF family - - - 0.000000000000000000000000000000008445 128.0
HFD1_k127_7411440_4 Glycosyl transferases group 1 - - - 0.000000000000000000000000001826 113.0
HFD1_k127_7425863_0 AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 572.0
HFD1_k127_7425863_1 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 442.0
HFD1_k127_7442170_0 Domain of unknown function (DUF1974) K06445 - - 0.0 1079.0
HFD1_k127_7442170_1 abc transporter, permease K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001627 254.0
HFD1_k127_7442170_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000002712 213.0
HFD1_k127_7442170_3 ABC transporter, ATP-binding protein K02065 - - 0.000000000000000000000000000000000000007168 149.0
HFD1_k127_7442170_4 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.0000000000000000000000000000000002847 137.0
HFD1_k127_7442170_5 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.0000000000000000000000000000785 120.0
HFD1_k127_7443009_0 VanZ like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 530.0
HFD1_k127_7443009_1 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 311.0
HFD1_k127_7443009_2 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000002284 205.0
HFD1_k127_7443009_3 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000001188 88.0
HFD1_k127_7443009_4 Uncharacterised protein family (UPF0093) K08973 - - 0.0000000000000000161 82.0
HFD1_k127_744363_0 TatD related DNase K07051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 460.0
HFD1_k127_744363_1 mannose-ethanolamine phosphotransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 427.0
HFD1_k127_744363_2 Domain of unknown function (DUF1864) K19981 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 405.0
HFD1_k127_744363_3 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K20940 - 1.14.13.218 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004963 400.0
HFD1_k127_744363_4 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006502 262.0
HFD1_k127_744363_5 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000002083 213.0
HFD1_k127_744363_6 - - - - 0.00000000000000000008313 101.0
HFD1_k127_7450224_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000004298 194.0
HFD1_k127_7450224_3 AI-2E family transporter - - - 0.00000000000000000000000002156 113.0
HFD1_k127_7454348_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 1.255e-231 720.0
HFD1_k127_7454348_1 Thiol disulfide interchange protein K03673 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 299.0
HFD1_k127_7454348_2 Sporulation related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000632 278.0
HFD1_k127_7454348_3 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.000000000000000000000000000000000004691 146.0
HFD1_k127_7455604_0 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 493.0
HFD1_k127_7455604_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000006698 198.0
HFD1_k127_7455604_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000003379 196.0
HFD1_k127_7458709_0 Belongs to the 5'-nucleotidase family K01081,K17224 - 3.1.3.5 5.444e-218 680.0
HFD1_k127_7458709_1 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 509.0
HFD1_k127_7458709_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 293.0
HFD1_k127_7458709_3 Acyl-CoA thioesterase K10805 - - 0.00000000000000000000000000000000000003468 145.0
HFD1_k127_7468176_0 - - - - 9.229e-235 732.0
HFD1_k127_7468176_1 TIGRFAM outer membrane autotransporter barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 583.0
HFD1_k127_7468176_2 Aminotransferase class I and II K14261 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 321.0
HFD1_k127_7468176_3 Belongs to the 4-oxalocrotonate tautomerase family K01821 - 5.3.2.6 0.000000000000000000000000000000000000000000000000000000000001248 211.0
HFD1_k127_7468176_4 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000002035 185.0
HFD1_k127_7468176_5 Protein conserved in bacteria - - - 0.00000000000000000000000000000002996 141.0
HFD1_k127_7468176_6 - - - - 0.000000000000000000002107 106.0
HFD1_k127_747331_0 fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 588.0
HFD1_k127_747331_1 Oxidoreductase FAD-binding domain K11933,K21832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 400.0
HFD1_k127_747331_2 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000006045 94.0
HFD1_k127_747331_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000002188 75.0
HFD1_k127_7494474_0 ABC transporter, ATP-binding protein K02471 - - 4.104e-267 838.0
HFD1_k127_7494474_1 chorismate binding enzyme K01665,K03342 - 2.6.1.85,4.1.3.38 8.079e-223 708.0
HFD1_k127_7494474_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 497.0
HFD1_k127_7494474_3 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000145 262.0
HFD1_k127_7494474_4 Lactoylglutathione lyase K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000193 216.0
HFD1_k127_7494474_5 bond formation protein DsbB K03611 - - 0.00000000000000000000000000000000000000006141 156.0
HFD1_k127_7497145_0 Histidinol phosphatase and related hydrolases of the PHP family - - - 0.0 1244.0
HFD1_k127_7497145_1 - - - - 0.00000000000000000000000000000000000000000000000000003078 190.0
HFD1_k127_7500970_0 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 344.0
HFD1_k127_7500970_1 extracellular alpha-helical protein K06894 - - 0.000000000000000000000000000000000000000001112 162.0
HFD1_k127_7500970_2 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000003431 79.0
HFD1_k127_7510676_0 branched-chain amino acid permease (azaleucine resistance) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004519 246.0
HFD1_k127_7510676_1 Belongs to the Smg family K03747 - - 0.00000000000000000000000000000000000000000000000000000000000003389 220.0
HFD1_k127_7510676_2 - - - - 0.00000000000000000000000000000000004542 139.0
HFD1_k127_7514119_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000603 350.0
HFD1_k127_7514119_1 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 304.0
HFD1_k127_7518379_0 Beta-lactamase - - - 1.778e-299 934.0
HFD1_k127_7518379_1 Acyl-CoA dehydrogenase, C-terminal domain K00249,K00255 - 1.3.8.7,1.3.8.8 6.19e-228 709.0
HFD1_k127_7518379_2 Belongs to the thiolase family K00626 - 2.3.1.9 3.061e-221 689.0
HFD1_k127_7518379_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 349.0
HFD1_k127_7518379_4 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002321 266.0
HFD1_k127_7518379_5 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000000001751 190.0
HFD1_k127_7518379_6 regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed - - - 0.00000000000000000000000000000000000000000000000006037 186.0
HFD1_k127_7518379_7 - - - - 0.000000000000000004985 88.0
HFD1_k127_7518379_8 KR domain K13774 - - 0.00000000000000002931 86.0
HFD1_k127_7518379_9 - - - - 0.000000008949 61.0
HFD1_k127_7518630_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 3.087e-290 899.0
HFD1_k127_7518630_1 Rod shape-determining protein mreD K03571 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005558 274.0
HFD1_k127_7526248_0 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.00000000000000000000000000000000000000000000000000000000007823 219.0
HFD1_k127_7526248_1 Receptor family ligand binding region K01999 - - 0.0000000000000000000001546 101.0
HFD1_k127_7531343_0 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 333.0
HFD1_k127_7531343_1 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000000000000000000000001575 214.0
HFD1_k127_7531343_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000001489 186.0
HFD1_k127_7531343_3 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000005731 179.0
HFD1_k127_7546369_0 Patatin-like phospholipase K07001 - - 1.398e-277 864.0
HFD1_k127_7546369_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286,K16079 - - 0.0000000001189 66.0
HFD1_k127_7564248_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0 1320.0
HFD1_k127_7564248_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0 1019.0
HFD1_k127_7564248_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 517.0
HFD1_k127_7564248_3 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 320.0
HFD1_k127_7564248_4 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000000000000000000000000000000003227 178.0
HFD1_k127_7568887_0 LysR substrate binding domain K03717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 471.0
HFD1_k127_7568887_1 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 394.0
HFD1_k127_7568887_2 - - - - 0.00000000000000000000000000000000000000000000000000000001321 200.0
HFD1_k127_7568887_3 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase - - - 0.0000000000000000000000000000000000000000001742 162.0
HFD1_k127_7568887_4 Evidence 4 Homologs of previously reported genes of K09981 - - 0.00000000000000000000000000001315 121.0
HFD1_k127_757490_0 BFD-like [2Fe-2S] binding domain K00362 - 1.7.1.15 0.0 1509.0
HFD1_k127_757490_1 Dynamin family - - - 0.0 1078.0
HFD1_k127_757490_2 TIGRFAM A G-specific adenine glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 495.0
HFD1_k127_757490_3 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 411.0
HFD1_k127_757490_4 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 406.0
HFD1_k127_757490_5 Rieske-like [2Fe-2S] domain K00363 - 1.7.1.15 0.000000000000000000000000000000000000000000000001117 175.0
HFD1_k127_7575081_0 PFAM Aminotransferase class I and II K14287 - 2.6.1.88 9.404e-208 651.0
HFD1_k127_7575081_1 Rhs element Vgr protein K11904 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 509.0
HFD1_k127_7575081_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 430.0
HFD1_k127_758177_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008299 252.0
HFD1_k127_758663_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406,K03776,K05874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001031 258.0
HFD1_k127_758663_1 PFAM Helix-turn-helix, type 11 domain protein - - - 0.00000000000000000000000000000002191 126.0
HFD1_k127_758666_0 Esterase of the alpha-beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 417.0
HFD1_k127_758666_1 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000009602 249.0
HFD1_k127_758666_3 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00002856 46.0
HFD1_k127_7597693_0 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009804 499.0
HFD1_k127_7597693_1 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 466.0
HFD1_k127_7597693_2 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 461.0
HFD1_k127_7597693_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 398.0
HFD1_k127_7597693_4 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007372 279.0
HFD1_k127_7597693_5 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000001416 162.0
HFD1_k127_7599639_0 Major Facilitator Superfamily K07552,K18552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 448.0
HFD1_k127_7599639_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001677 271.0
HFD1_k127_7599639_2 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.0000000000000000001607 87.0
HFD1_k127_7624864_0 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 524.0
HFD1_k127_7624864_1 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 439.0
HFD1_k127_7624864_2 reductase K00059 - 1.1.1.100 0.0000000000000000000108 91.0
HFD1_k127_762682_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 1.853e-239 743.0
HFD1_k127_762682_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 527.0
HFD1_k127_762682_2 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 533.0
HFD1_k127_762682_3 Belongs to the arginase family K01476,K01480,K12255,K18459 - 3.5.3.1,3.5.3.11,3.5.3.17,3.5.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 509.0
HFD1_k127_762682_4 ThiF family K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 402.0
HFD1_k127_762682_5 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 326.0
HFD1_k127_762682_6 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000000000000000108 187.0
HFD1_k127_762682_7 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000000000007523 154.0
HFD1_k127_7628559_0 histidine kinase HAMP region domain protein K03406,K03776,K05874,K05875 - - 5.489e-239 747.0
HFD1_k127_7628559_1 Sugar (and other) transporter - - - 5.277e-209 656.0
HFD1_k127_7628559_10 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000000000000000000000000001054 159.0
HFD1_k127_7628559_11 Integral membrane sensor signal transduction histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000002444 159.0
HFD1_k127_7628559_12 - - - - 0.0000000000000000000000000000000001429 137.0
HFD1_k127_7628559_13 - - - - 0.00000000000000000006474 93.0
HFD1_k127_7628559_2 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 621.0
HFD1_k127_7628559_3 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008442 512.0
HFD1_k127_7628559_4 Major Facilitator K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009811 489.0
HFD1_k127_7628559_5 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007017 464.0
HFD1_k127_7628559_6 2-hydroxy-3-oxopropionate reductase K00042 - 1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 429.0
HFD1_k127_7628559_7 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003513 272.0
HFD1_k127_7628559_8 Translation initiation factor K03113 - - 0.0000000000000000000000000000000000000000000000003299 180.0
HFD1_k127_7628559_9 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000001476 168.0
HFD1_k127_7629471_0 Diguanylate cyclase - - - 9.454e-205 666.0
HFD1_k127_7629471_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 551.0
HFD1_k127_7629471_2 diguanylate cyclase - - - 0.000000000000000000000000000000000000002323 152.0
HFD1_k127_7629471_3 MAPEG family - - - 0.0000000000000000000000000000000003388 138.0
HFD1_k127_7629471_4 7TM diverse intracellular signalling - - - 0.000000000000000000000000000000001084 146.0
HFD1_k127_7632666_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 431.0
HFD1_k127_7632666_1 Type VI secretion system, VipA, VC_A0107 or Hcp2 - - - 0.000000000000121 76.0
HFD1_k127_763885_0 Murein transglycosylase K08305 - - 2.918e-203 638.0
HFD1_k127_763885_1 RESPONSE REGULATOR receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 543.0
HFD1_k127_763885_10 PFAM peptidase S16 lon domain protein K07157 - - 0.000000000000000000000000000005538 124.0
HFD1_k127_763885_11 CAAX protease self-immunity K07052 - - 0.000000000001725 71.0
HFD1_k127_763885_2 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 383.0
HFD1_k127_763885_3 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009244 331.0
HFD1_k127_763885_4 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 321.0
HFD1_k127_763885_5 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 292.0
HFD1_k127_763885_6 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 285.0
HFD1_k127_763885_7 Flavodoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009417 243.0
HFD1_k127_763885_8 Excalibur calcium-binding domain - - - 0.0000000000000000000000000000000000000000000009672 174.0
HFD1_k127_763885_9 - - - - 0.0000000000000000000000000000001348 125.0
HFD1_k127_7640216_0 Urea ABC transporter, urea binding protein K11959 - - 0.0000000000000000000000000000000000000000000000000000000000007873 216.0
HFD1_k127_7640216_1 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000001264 200.0
HFD1_k127_7640216_2 Flagellar Assembly Protein A K09749 - - 0.000000000000000000000000000000001266 135.0
HFD1_k127_7646875_0 toluene tolerance K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 299.0
HFD1_k127_7646875_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008027 291.0
HFD1_k127_7646875_2 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008158 273.0
HFD1_k127_7646875_3 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000002514 171.0
HFD1_k127_7646875_4 STAS domain K07122 - - 0.0000000000000000000000000000000000005998 147.0
HFD1_k127_765060_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 4.512e-299 920.0
HFD1_k127_765060_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 6.778e-260 805.0
HFD1_k127_765060_2 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 3.575e-225 703.0
HFD1_k127_765060_3 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 2.156e-219 686.0
HFD1_k127_765060_4 Colicin V production protein K03558 - - 0.000000000000000000000000000000000000000000000000000000000000000204 225.0
HFD1_k127_765060_5 Sporulation related domain K03749 - - 0.000000000000000000000000000000000000000000000000001598 193.0
HFD1_k127_765060_6 - - - - 0.00000000000335 67.0
HFD1_k127_765060_7 - - - - 0.00000002245 57.0
HFD1_k127_7656924_0 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 349.0
HFD1_k127_7656924_2 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.000000000000000000000000000000000000006738 153.0
HFD1_k127_7656924_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000001056 62.0
HFD1_k127_766158_0 His Kinase A (phosphoacceptor) domain - - - 0.0 1141.0
HFD1_k127_766158_1 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008577 247.0
HFD1_k127_7667538_0 Domain of unknown function (DUF4157) - - - 0.000000000000000000000000000000000000000000000000000000000001113 226.0
HFD1_k127_7667538_1 Domain of unknown function (DUF4157) - - - 0.000000000000000000000000000000003571 142.0
HFD1_k127_7667538_2 Domain of unknown function (DUF4157) - - - 0.00000000000000000000000000001498 137.0
HFD1_k127_7670712_0 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 390.0
HFD1_k127_7670712_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000001891 197.0
HFD1_k127_7670712_2 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000000000002707 140.0
HFD1_k127_7692200_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 5.443e-198 618.0
HFD1_k127_770353_0 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 4.662e-252 791.0
HFD1_k127_770353_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 595.0
HFD1_k127_770353_2 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 527.0
HFD1_k127_770353_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000004899 176.0
HFD1_k127_7703635_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000894 266.0
HFD1_k127_7703635_1 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000143 189.0
HFD1_k127_7713147_0 HemX, putative uroporphyrinogen-III C-methyltransferase K02496,K13543 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004036 278.0
HFD1_k127_7713147_1 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000001414 213.0
HFD1_k127_7713147_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000003603 167.0
HFD1_k127_7715656_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1310.0
HFD1_k127_7715656_1 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 307.0
HFD1_k127_7715656_2 Belongs to the skp family K06142 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007957 249.0
HFD1_k127_7715656_3 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000003923 121.0
HFD1_k127_7715656_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000415 70.0
HFD1_k127_7715656_5 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.000000006475 63.0
HFD1_k127_7722490_0 Beta-ketoacyl synthase, N-terminal domain K00647 - 2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 464.0
HFD1_k127_7722490_1 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 330.0
HFD1_k127_7722490_2 Polysaccharide deacetylase - - - 0.00000000000000000000000000000002996 127.0
HFD1_k127_7724963_0 Histidine kinase K07645 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 610.0
HFD1_k127_7724963_1 Bacterial regulatory proteins, tetR family K16137 - - 0.00000000000000000000000000000000000000000000000000000000007627 209.0
HFD1_k127_7724963_2 Belongs to the thiolase family K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000003664 176.0
HFD1_k127_7734456_0 ABC transporter, ATP-binding protein K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 602.0
HFD1_k127_7734456_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 591.0
HFD1_k127_7734456_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 584.0
HFD1_k127_7734456_3 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 436.0
HFD1_k127_7734456_4 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 389.0
HFD1_k127_7734456_5 Alpha/beta hydrolase family K06889 - - 0.0000000000000000000000000000000000000000000000000000000000001921 226.0
HFD1_k127_7734456_6 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000734 169.0
HFD1_k127_7746770_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2044.0
HFD1_k127_7746770_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000009 114.0
HFD1_k127_7746904_0 GH3 auxin-responsive promoter - - - 8.575e-219 682.0
HFD1_k127_7746904_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 1.466e-217 679.0
HFD1_k127_7746904_2 - - - - 4.994e-215 670.0
HFD1_k127_7746904_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 372.0
HFD1_k127_7746904_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 296.0
HFD1_k127_7750169_0 Serine threonine protein kinase - - - 2.282e-203 634.0
HFD1_k127_7750169_1 phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 566.0
HFD1_k127_7750169_2 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 478.0
HFD1_k127_7750169_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 426.0
HFD1_k127_7750169_4 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007147 347.0
HFD1_k127_7750169_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000004273 253.0
HFD1_k127_7750169_6 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000007507 72.0
HFD1_k127_7757592_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789 - - 5.53e-310 964.0
HFD1_k127_7765162_0 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 510.0
HFD1_k127_7765162_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 344.0
HFD1_k127_7765162_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002821 255.0
HFD1_k127_7767555_0 Sulfite reductase K00381,K00392 - 1.8.1.2,1.8.7.1 3.874e-281 869.0
HFD1_k127_7767555_1 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 409.0
HFD1_k127_7767555_2 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 317.0
HFD1_k127_7771583_0 Histidine kinase K07638 - 2.7.13.3 5.62e-251 778.0
HFD1_k127_7771583_1 Ammonium Transporter K03320,K06580 - - 7.025e-231 719.0
HFD1_k127_7771583_2 PFAM response regulator receiver K02483,K07659 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 469.0
HFD1_k127_7771583_3 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000055 271.0
HFD1_k127_7771583_4 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000000000000000000000000000000000000004518 169.0
HFD1_k127_7772564_0 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 405.0
HFD1_k127_7772564_1 PFAM Glutathione S-transferase domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 308.0
HFD1_k127_7772564_2 Protein of unknown function (DUF1428) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004401 252.0
HFD1_k127_7772564_3 DNA primase small subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000006687 233.0
HFD1_k127_7772564_4 Glutathione S-transferase - - - 0.0000001525 54.0
HFD1_k127_7772564_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000009687 59.0
HFD1_k127_7774039_0 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000586 495.0
HFD1_k127_7774039_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009933 422.0
HFD1_k127_7774039_2 Nudix hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 305.0
HFD1_k127_7774039_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002709 274.0
HFD1_k127_7774039_4 TM2 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008053 255.0
HFD1_k127_7774039_5 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000000000000000000000006908 227.0
HFD1_k127_7774039_6 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000000000001894 215.0
HFD1_k127_7774039_7 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000002903 179.0
HFD1_k127_7774039_8 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000632 168.0
HFD1_k127_7774039_9 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000000001942 143.0
HFD1_k127_7776836_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 292.0
HFD1_k127_7776836_1 UPF0114 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 290.0
HFD1_k127_7776836_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000009532 105.0
HFD1_k127_7779818_0 best DB hits BLAST gb AAD45539.1 - - - 0.00000000000000000000000000000000000000000000000001146 198.0
HFD1_k127_7787042_0 phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 457.0
HFD1_k127_7787042_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 342.0
HFD1_k127_7787042_2 PFAM Protein kinase K12132 - 2.7.11.1 0.0000000000000005846 79.0
HFD1_k127_7792886_0 Hydrolase CocE NonD family K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008433 457.0
HFD1_k127_7792886_1 A domain family that is part of the cupin metalloenzyme superfamily. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003558 282.0
HFD1_k127_7792886_2 PFAM OsmC family protein K04063 - - 0.00000000000000000000000000000000000000000000000000000000000000005306 225.0
HFD1_k127_7792886_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000741 157.0
HFD1_k127_7792886_4 alpha beta - - - 0.000000000000000000000000000000001826 140.0
HFD1_k127_7792886_5 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.00000000000000000000000000000001888 139.0
HFD1_k127_7792886_6 AMP-binding enzyme C-terminal domain - - - 0.0000000000000005358 88.0
HFD1_k127_7792886_7 PFAM phosphate transporter K03306 - - 0.0000000001433 61.0
HFD1_k127_7805036_0 Diguanylate cyclase K14051 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005525,GO:0008081,GO:0008150,GO:0010468,GO:0010608,GO:0016787,GO:0016788,GO:0017076,GO:0019001,GO:0019222,GO:0031279,GO:0031280,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042578,GO:0043086,GO:0043167,GO:0043168,GO:0044092,GO:0050789,GO:0050790,GO:0060255,GO:0065007,GO:0065009,GO:0071111,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.1.4.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 396.0
HFD1_k127_7805036_1 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.000000000000000000000000000000000000000000000000000012 198.0
HFD1_k127_7805411_0 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 609.0
HFD1_k127_7805411_1 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 479.0
HFD1_k127_7805411_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002746 236.0
HFD1_k127_7805411_3 Required for insertion of 4Fe-4S clusters K15724 - - 0.00000000000000000000000000000000000000000000000000000000000007843 216.0
HFD1_k127_7805411_4 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000000002332 186.0
HFD1_k127_7805411_5 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000007025 90.0
HFD1_k127_7815288_0 GAF domain K21405 - - 1.356e-276 864.0
HFD1_k127_7815288_1 Belongs to the mannose-6-phosphate isomerase type 2 family K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 460.0
HFD1_k127_7815288_2 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 438.0
HFD1_k127_7815288_3 HAD-hyrolase-like K22292 - 3.1.3.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007458 345.0
HFD1_k127_7815288_4 belongs to the aldehyde dehydrogenase family K00138 - - 0.0003365 45.0
HFD1_k127_7820199_0 Transposase DDE domain group 1 - - - 0.000000000000000000000000006818 125.0
HFD1_k127_7822033_0 - - - - 0.0000000000000000000000000000000000000000000003722 189.0
HFD1_k127_7822033_1 C-terminal domain of CHU protein family - - - 0.000000000000000000000000002522 129.0
HFD1_k127_7822033_2 COG2931 RTX toxins and related Ca2 -binding - - - 0.000000003465 70.0
HFD1_k127_7825379_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 357.0
HFD1_k127_7825379_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000006835 186.0
HFD1_k127_7825379_2 protein-(glutamine-N5) methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000003041 189.0
HFD1_k127_7825379_3 6-pyruvoyl tetrahydropterin synthase - - - 0.0000000000000000000000000000000000000000000002008 170.0
HFD1_k127_7825379_4 RibD C-terminal domain K00082 - 1.1.1.193 0.000000000001965 68.0
HFD1_k127_7840164_0 Outer membrane efflux protein K18903 - - 6.971e-200 637.0
HFD1_k127_7840164_1 Binding-protein-dependent transport system inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 444.0
HFD1_k127_7840164_2 binding-protein-dependent transport systems inner membrane component K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 430.0
HFD1_k127_7840164_3 Transporter, hydrophobe amphiphile efflux-1 (HAE1) family K18902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 361.0
HFD1_k127_7840164_4 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000004209 234.0
HFD1_k127_7840164_5 Hydantoin racemase - - - 0.0000000000000000000000000000000000000002249 159.0
HFD1_k127_7840164_6 Outer membrane protein (Porin) - - - 0.0000000000000000000000000000000000003521 155.0
HFD1_k127_7840164_7 - - - - 0.00001529 52.0
HFD1_k127_7858372_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 2.914e-204 639.0
HFD1_k127_7858372_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 480.0
HFD1_k127_7858372_2 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 286.0
HFD1_k127_7858372_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000672 268.0
HFD1_k127_7858372_4 riboflavin synthase, alpha K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000005239 176.0
HFD1_k127_7866695_0 Polysaccharide biosynthesis protein - - - 0.0 1026.0
HFD1_k127_7866695_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 619.0
HFD1_k127_7866695_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 362.0
HFD1_k127_7866695_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000003347 188.0
HFD1_k127_7878578_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 7.033e-202 632.0
HFD1_k127_7878578_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007341 513.0
HFD1_k127_7878578_2 PAP2 superfamily - - - 0.0000000000000000000000000000000001664 139.0
HFD1_k127_7879884_0 Metal-dependent hydrolase K07044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 516.0
HFD1_k127_7879884_1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 462.0
HFD1_k127_7879884_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 449.0
HFD1_k127_7879884_3 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 415.0
HFD1_k127_7879884_4 Transcriptional regulatory protein, C terminal K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000146 258.0
HFD1_k127_7879884_5 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000003006 243.0
HFD1_k127_788185_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 0.0 1114.0
HFD1_k127_788185_1 XdhC Rossmann domain K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 546.0
HFD1_k127_788185_2 LysR family K16135 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 510.0
HFD1_k127_788185_3 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 385.0
HFD1_k127_788185_4 MobA-Related Protein K07141,K19190 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019720,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061602,GO:0070567,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902759,GO:1902760 1.1.1.328,2.7.7.76 0.00000000000000000000000000000000000000000000000000000000000006758 220.0
HFD1_k127_7882783_0 GMC oxidoreductase K03333 - 1.1.3.6 9.535e-299 923.0
HFD1_k127_7882783_1 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 4.292e-241 753.0
HFD1_k127_7882783_10 Belongs to the 'phage' integrase family - - - 0.00003538 47.0
HFD1_k127_7882783_2 Flavin-binding monooxygenase-like K07222,K18277 - 1.14.13.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008496 451.0
HFD1_k127_7882783_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009533 389.0
HFD1_k127_7882783_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000001626 219.0
HFD1_k127_7882783_5 Ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.000000000000000000000000000000000000000000000000000000000000104 213.0
HFD1_k127_7882783_6 - - - - 0.000000000000000000000000000000000000000000000000000000000001054 216.0
HFD1_k127_7882783_7 - - - - 0.000000000000000000000000000000000000000000000000000000001095 211.0
HFD1_k127_7882783_8 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0000000000000000004564 87.0
HFD1_k127_7882783_9 - - - - 0.00000000001301 73.0
HFD1_k127_788529_0 Pectinacetylesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 338.0
HFD1_k127_788529_1 Transcriptional regulator K03576 - - 0.0001086 45.0
HFD1_k127_7885709_0 LysR substrate binding domain K03717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 443.0
HFD1_k127_7885709_1 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 402.0
HFD1_k127_7885709_2 Belongs to the BI1 family K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 342.0
HFD1_k127_7885709_3 cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000001182 190.0
HFD1_k127_7885709_4 diguanylate cyclase activity K21021 - 2.7.7.65 0.00000000000000000000000000000000000000002734 169.0
HFD1_k127_7893262_0 histidine kinase HAMP region domain protein K03406,K03776,K05874,K05875 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 507.0
HFD1_k127_7893262_1 COG0784 FOG CheY-like receiver - - - 0.000000000000000000000000000001511 125.0
HFD1_k127_7893262_2 NADPH-dependent FMN reductase K19784 - - 0.000000000000000000000000008232 111.0
HFD1_k127_7893262_3 - - - - 0.0000000000007626 74.0
HFD1_k127_7918020_0 Cytochrome P450 - - - 9.49e-208 655.0
HFD1_k127_7918020_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs K05541 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 477.0
HFD1_k127_7918020_2 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006159 400.0
HFD1_k127_7918020_3 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000004037 145.0
HFD1_k127_7918020_4 Chalcone isomerase-like - - - 0.0000924 48.0
HFD1_k127_7920703_0 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 329.0
HFD1_k127_7920703_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002492 284.0
HFD1_k127_7922683_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1121.0
HFD1_k127_7922683_1 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.000004207 49.0
HFD1_k127_7924619_0 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 497.0
HFD1_k127_7924619_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000003521 219.0
HFD1_k127_7924619_2 Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single strand break in duplex DNA K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000001825 104.0
HFD1_k127_7934139_0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 1.418e-205 642.0
HFD1_k127_7934139_1 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 516.0
HFD1_k127_7934139_2 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 358.0
HFD1_k127_7934139_3 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000001047 167.0
HFD1_k127_7952469_0 single-stranded-DNA-specific exonuclease RecJ K07462 - - 9.554e-277 856.0
HFD1_k127_7952469_1 Hemolysin-type calcium-binding - - - 0.0000000000000000000000000000000000000000000000000000008614 198.0
HFD1_k127_7956430_0 SMART alpha amylase catalytic sub domain K00705,K06044 - 2.4.1.25,5.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008386 567.0
HFD1_k127_7959635_0 ABC transporter, transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000248 234.0
HFD1_k127_7959635_1 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000000000005965 194.0
HFD1_k127_7959635_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000001988 167.0
HFD1_k127_7964696_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1436.0
HFD1_k127_7964696_1 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 - 6.3.4.5 6.676e-263 814.0
HFD1_k127_7964696_2 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.00000000000000000000000000000000000000000000000000000001 202.0
HFD1_k127_7964696_3 17 kDa surface antigen - - - 0.000000000000000000001231 100.0
HFD1_k127_7964696_4 17 kDa surface antigen - - - 0.000000003612 61.0
HFD1_k127_7988061_0 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 502.0
HFD1_k127_7988061_1 AIR synthase related protein domain protein K07123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 494.0
HFD1_k127_7988061_2 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 292.0
HFD1_k127_7988061_3 flavoprotein involved in K transport - - - 0.0000000000000000000000000000000000000000008003 158.0
HFD1_k127_798970_0 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 542.0
HFD1_k127_798970_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000002254 168.0
HFD1_k127_8002363_0 Flagellar hook protein FlgE K02390 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 496.0
HFD1_k127_8002363_1 Flagellar basal-body rod protein FlgF K02391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 387.0
HFD1_k127_8002363_2 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 325.0
HFD1_k127_8002363_3 Belongs to the flagella basal body rod proteins family K02388 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005688 241.0
HFD1_k127_8002363_4 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.000000000000000000000000000000000000000000000000000000000006184 212.0
HFD1_k127_8002363_5 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.00000000000000000000000000000000000000000000000000000000003081 212.0
HFD1_k127_8002363_6 anti-sigma-28 factor K02398 - - 0.0000000000000000000000008695 107.0
HFD1_k127_8012938_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0 1095.0
HFD1_k127_8012938_1 helix_turn_helix ASNC type K03719 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001538 244.0
HFD1_k127_8017746_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1135.0
HFD1_k127_8017746_1 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 462.0
HFD1_k127_8017746_2 Alpha beta hydrolase K01066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 407.0
HFD1_k127_8017746_3 Type ii and iii secretion system protein - - - 0.00000000000000000000000000000000000000000000000205 183.0
HFD1_k127_8017746_4 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.000000000000000000000000000000000004911 136.0
HFD1_k127_8017746_5 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000001677 93.0
HFD1_k127_8017746_6 Signal transduction histidine kinase - - - 0.0000000000000795 77.0
HFD1_k127_807168_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 4.69e-230 719.0
HFD1_k127_807168_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.266e-220 689.0
HFD1_k127_813119_0 Iron hydrogenase small subunit - - - 9.571e-282 874.0
HFD1_k127_813119_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 5.802e-259 813.0
HFD1_k127_813119_10 Las17-binding protein actin regulator - - - 0.0005261 46.0
HFD1_k127_813119_2 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 441.0
HFD1_k127_813119_3 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001076 274.0
HFD1_k127_813119_4 Erythromycin esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000001078 231.0
HFD1_k127_813119_5 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000002484 204.0
HFD1_k127_813119_6 TPM domain - - - 0.00000000000000000000000000000000000000000000000000000001177 210.0
HFD1_k127_813119_7 Iron hydrogenase small subunit K00336,K18006 - 1.12.1.2,1.6.5.3 0.000000000000000000000000000000000000000000000001752 176.0
HFD1_k127_813119_8 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000006324 160.0
HFD1_k127_813119_9 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000002347 100.0
HFD1_k127_814335_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 566.0
HFD1_k127_814335_1 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 433.0
HFD1_k127_814335_2 Cbb3-type cytochrome oxidase K00407 - - 0.0000001396 56.0
HFD1_k127_820870_0 TIGRFAM arsenite-activated ATPase ArsA K01551 - 3.6.3.16 1.105e-238 754.0
HFD1_k127_820870_1 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 299.0
HFD1_k127_820870_2 Protein of unknown function DUF86 - - - 0.00000000000000000000000000000000000000000004684 163.0
HFD1_k127_821715_0 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 478.0
HFD1_k127_821715_1 Outer membrane efflux protein K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009911 390.0
HFD1_k127_821715_2 SapC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007844 331.0
HFD1_k127_822716_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1660.0
HFD1_k127_822716_1 Histidine kinase - - - 0.0 1364.0
HFD1_k127_822716_2 Peptidase family M3 K01414 - 3.4.24.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 507.0
HFD1_k127_822716_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 489.0
HFD1_k127_822716_4 Regulator K13041 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 391.0
HFD1_k127_822716_5 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 0.00000000000000004639 81.0
HFD1_k127_828596_0 Histidine kinase - - - 0.0 1025.0
HFD1_k127_828596_1 Domain of unknown function (DUF4390) - - - 0.00000000000000000000000000000000000000000000000000000000001022 211.0
HFD1_k127_849500_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 4.092e-244 766.0
HFD1_k127_849500_1 Flavodoxin-like fold K00355,K11746,K11748 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 295.0
HFD1_k127_849500_2 Ferritin, Dps family protein K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002064 274.0
HFD1_k127_849500_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11745,K11747 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001982 259.0
HFD1_k127_854245_0 carbohydrate binding K13688 - - 0.0 1746.0
HFD1_k127_858496_0 PFAM AMP-dependent synthetase and ligase K20034 - 6.2.1.44 1.84e-316 973.0
HFD1_k127_858496_1 branched-chain amino acid K01999 - - 4.753e-227 708.0
HFD1_k127_858496_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000003145 121.0
HFD1_k127_865426_0 urea carboxylase - - - 0.0 1272.0
HFD1_k127_865426_1 acyl-CoA dehydrogenase - - - 1.249e-241 749.0
HFD1_k127_865426_2 acyl-CoA dehydrogenase - - - 1.128e-204 650.0
HFD1_k127_865426_3 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 533.0
HFD1_k127_865426_4 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 512.0
HFD1_k127_865426_5 transposase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 356.0
HFD1_k127_865426_6 - - - - 0.00000000000000000000000006425 109.0
HFD1_k127_868670_0 Type VI secretion K11896 - - 4.55e-312 970.0
HFD1_k127_868670_1 Type VI secretion, TssG K11895 - - 0.0000000000000000000000000000000000000000000000001331 184.0
HFD1_k127_868670_2 TIGRFAM type VI secretion system lysozyme-related protein K11897 - - 0.000000000000000000000001154 106.0
HFD1_k127_874741_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 572.0
HFD1_k127_874741_1 Aminotransferase class-V K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 293.0
HFD1_k127_874741_2 Nitrogen fixation protein K02593 - - 0.000000000000000000000000000001045 123.0
HFD1_k127_874741_3 - - - - 0.0000000000000000000000000001168 120.0
HFD1_k127_877165_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 412.0
HFD1_k127_877165_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009908 312.0
HFD1_k127_877165_2 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000001902 188.0
HFD1_k127_877165_3 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.000000000000000000000000000000000000000000000008196 179.0
HFD1_k127_877165_4 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.00000000000001209 77.0
HFD1_k127_88549_0 Belongs to the glutamate synthase family K22083 - 2.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008489 553.0
HFD1_k127_88549_1 - - - - 0.00000000000000000000000000000000000003797 152.0
HFD1_k127_88549_2 Secretory lipase - - - 0.00000000000004113 72.0
HFD1_k127_914658_0 - K00201 GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0044237,GO:0044281 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 485.0
HFD1_k127_914658_1 ATP-grasp domain K01499,K06913 - 3.5.4.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 298.0
HFD1_k127_914658_2 Protein of unknown function (DUF1464) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002414 282.0
HFD1_k127_914658_3 Formylmethanofuran dehydrogenase subunit A K00200 GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0044237,GO:0044281 1.2.7.12 0.0000000000000000000000000000000006646 133.0
HFD1_k127_921664_0 Biotin carboxylase K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 1.076e-277 856.0
HFD1_k127_921664_1 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 396.0
HFD1_k127_921664_2 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000003131 259.0
HFD1_k127_921664_3 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000000000000000000003101 229.0
HFD1_k127_940414_0 Domain of Unknown Function (DUF748) - - - 7.399e-223 699.0
HFD1_k127_940414_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 440.0
HFD1_k127_940414_2 MerR HTH family regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 346.0
HFD1_k127_940414_3 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000000000000000000000007613 210.0
HFD1_k127_943727_0 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 478.0
HFD1_k127_943727_1 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000102 233.0
HFD1_k127_959266_0 Diguanylate cyclase K21023 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 481.0
HFD1_k127_959266_1 homocysteine S-methyltransferase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 359.0
HFD1_k127_959266_2 Diguanylate cyclase K21023 - 2.7.7.65 0.000000000000000000000000000000000000000000000009755 174.0
HFD1_k127_965065_0 Rhs element Vgr protein K11904 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 504.0
HFD1_k127_965065_1 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 458.0
HFD1_k127_965065_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000007927 119.0
HFD1_k127_968715_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 426.0
HFD1_k127_968715_1 Beta-lactamase - - - 0.00000000000000000000000000000008285 130.0
HFD1_k127_973890_0 Major Facilitator Superfamily K02575 - - 8.776e-225 702.0
HFD1_k127_973890_1 PHB de-polymerase C-terminus K05973 - 3.1.1.75 1.397e-223 702.0
HFD1_k127_973890_2 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 401.0
HFD1_k127_973890_3 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 391.0
HFD1_k127_973890_4 Uncharacterised protein family (UPF0149) K07039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005479 370.0
HFD1_k127_973890_5 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004615 271.0
HFD1_k127_973890_6 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001334 246.0
HFD1_k127_973890_7 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000001057 154.0
HFD1_k127_974755_0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 467.0
HFD1_k127_974755_1 Protein of unknown function, DUF484 K09921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 345.0
HFD1_k127_974755_2 chemotaxis sensory transducer K03406,K03776,K05874 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006697 276.0
HFD1_k127_974755_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000007411 265.0
HFD1_k127_986211_0 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 1.725e-279 862.0
HFD1_k127_986211_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 406.0
HFD1_k127_986211_2 histidine kinase HAMP region domain protein K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008605 347.0
HFD1_k127_986211_3 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003801 265.0
HFD1_k127_986211_4 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000007665 148.0
HFD1_k127_986211_5 Cytochrome c K08738 - - 0.00000000000000000000000000000000002024 143.0
HFD1_k127_986211_6 Prokaryotic cytochrome b561 K12262 - - 0.0000000000000000000000000000000008945 137.0
HFD1_k127_988190_0 GMC oxidoreductase - - - 2.53e-297 917.0
HFD1_k127_988190_1 Transcriptional regulator - - - 1.282e-236 739.0
HFD1_k127_988190_2 2-nitropropane dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 536.0
HFD1_k127_988190_3 PFAM Aminotransferase class I and II K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 438.0
HFD1_k127_988190_4 aminotransferase class I and II K00375 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007799 379.0
HFD1_k127_988190_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001072 244.0
HFD1_k127_996864_0 Histidine kinase - - - 2.065e-214 685.0
HFD1_k127_996864_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002694 269.0