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Overview

ID MAG01631
Name HFD2_bin.14
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Terriglobia
Order Bryobacterales
Family Bryobacteraceae
Genus JAJPJX01
Species
Assembly information
Completeness (%) 87.09
Contamination (%) 6.36
GC content (%) 67.0
N50 (bp) 22,902
Genome size (bp) 6,662,482

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes5262

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_1020796_0 transport - - - 2.638e-296 945.0
HFD2_k127_1020796_1 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 392.0
HFD2_k127_1020796_2 - - - - 0.000000000005413 72.0
HFD2_k127_1048565_0 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 0.0 1472.0
HFD2_k127_1048565_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 551.0
HFD2_k127_1048565_10 toxin-antitoxin pair type II binding - - - 0.00000343 53.0
HFD2_k127_1048565_11 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0005687 47.0
HFD2_k127_1048565_2 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008033 447.0
HFD2_k127_1048565_3 serine-type endopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 445.0
HFD2_k127_1048565_4 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 368.0
HFD2_k127_1048565_5 Di-haem oxidoreductase, putative peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 331.0
HFD2_k127_1048565_6 BNR repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000005009 251.0
HFD2_k127_1048565_7 unfolded protein binding - - - 0.00000000000000000000000000000000000000000000000000000000007716 222.0
HFD2_k127_1048565_8 Coagulation factor 5 8 type domain protein K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000003292 179.0
HFD2_k127_1048565_9 Cupredoxin-like domain K02275 - 1.9.3.1 0.0000000002174 72.0
HFD2_k127_1095240_0 amino acid - - - 6.045e-257 806.0
HFD2_k127_1095240_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 1.169e-240 750.0
HFD2_k127_1095240_10 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008041 325.0
HFD2_k127_1095240_11 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008615 329.0
HFD2_k127_1095240_12 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006145 307.0
HFD2_k127_1095240_13 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 297.0
HFD2_k127_1095240_14 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001643 278.0
HFD2_k127_1095240_15 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001546 251.0
HFD2_k127_1095240_16 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000000000000009822 218.0
HFD2_k127_1095240_18 - - - - 0.000000000000000000000000000000000000000000000000000000004536 200.0
HFD2_k127_1095240_19 PFAM Redoxin - - - 0.000000000000000000000000000000000000000000000000000003349 195.0
HFD2_k127_1095240_2 PFAM Aminotransferase class-III K01845 - 5.4.3.8 2.4e-216 677.0
HFD2_k127_1095240_20 domain, Protein K03112 - - 0.00000000000000000000000000000000000000000000000000009376 202.0
HFD2_k127_1095240_21 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000002224 192.0
HFD2_k127_1095240_24 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000001718 142.0
HFD2_k127_1095240_25 - - - - 0.0000000000188 70.0
HFD2_k127_1095240_26 Domain of Unknown Function (DUF350) - - - 0.000000004402 59.0
HFD2_k127_1095240_3 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 2.55e-214 685.0
HFD2_k127_1095240_4 PFAM Lytic transglycosylase catalytic K08309 - - 1.248e-210 679.0
HFD2_k127_1095240_5 PFAM aminotransferase, class I K10907 - - 1.025e-197 621.0
HFD2_k127_1095240_6 C-terminal, D2-small domain, of ClpB protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 596.0
HFD2_k127_1095240_7 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 492.0
HFD2_k127_1095240_8 Doxx family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006864 385.0
HFD2_k127_1095240_9 xylan catabolic process K03932,K07177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 372.0
HFD2_k127_1102827_0 transport - - - 0.0 1089.0
HFD2_k127_1102827_1 MacB-like periplasmic core domain - - - 1.052e-305 968.0
HFD2_k127_1102827_10 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 439.0
HFD2_k127_1102827_11 Iron-containing alcohol dehydrogenase K00001,K13954 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 357.0
HFD2_k127_1102827_12 SpoIVB peptidase S55 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 323.0
HFD2_k127_1102827_13 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 327.0
HFD2_k127_1102827_14 protein kinase related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 312.0
HFD2_k127_1102827_15 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000006064 248.0
HFD2_k127_1102827_16 - - - - 0.000000000000000000000000000000000000000000000000000000000002881 214.0
HFD2_k127_1102827_17 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000000000000000187 199.0
HFD2_k127_1102827_18 Methyltransferase domain - - - 0.0000000000000000000000000000000000000001045 160.0
HFD2_k127_1102827_19 - - - - 0.0000000000000000000005048 113.0
HFD2_k127_1102827_2 PFAM SMP-30 Gluconolaconase - - - 2.224e-274 862.0
HFD2_k127_1102827_20 Protein of unknown function (DUF3311) - - - 0.0000000001097 66.0
HFD2_k127_1102827_3 cellulose binding - - - 8.775e-270 852.0
HFD2_k127_1102827_4 Alpha-L-fucosidase K01206 - 3.2.1.51 6.406e-198 630.0
HFD2_k127_1102827_5 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 567.0
HFD2_k127_1102827_6 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 582.0
HFD2_k127_1102827_7 protein kinase related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008364 531.0
HFD2_k127_1102827_8 PFAM Prenyltransferase squalene oxidase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 504.0
HFD2_k127_1102827_9 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007036 478.0
HFD2_k127_1111611_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 1.205e-308 966.0
HFD2_k127_1111611_1 Ammonium transporter K03320 - - 6.735e-282 874.0
HFD2_k127_1111611_2 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 434.0
HFD2_k127_1111611_3 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 306.0
HFD2_k127_1111611_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 313.0
HFD2_k127_1111611_5 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000002058 242.0
HFD2_k127_1111611_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000005382 218.0
HFD2_k127_1111611_8 ThiS family K03636 GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000005747 64.0
HFD2_k127_113580_0 dna ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 482.0
HFD2_k127_113580_1 PFAM ATP dependent DNA ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 480.0
HFD2_k127_113580_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 304.0
HFD2_k127_113580_3 FGGY family of carbohydrate kinases, N-terminal domain K11214 - 2.7.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009662 294.0
HFD2_k127_113580_4 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001008 285.0
HFD2_k127_113580_5 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001928 270.0
HFD2_k127_113580_6 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000747 150.0
HFD2_k127_113580_7 AntiSigma factor - - - 0.00000000000000000000000000000000122 140.0
HFD2_k127_1199451_0 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 3.81e-293 905.0
HFD2_k127_1199451_1 - - - - 2.593e-255 814.0
HFD2_k127_1199451_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001639 252.0
HFD2_k127_1199451_3 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000003202 204.0
HFD2_k127_1201277_0 PFAM NADH Ubiquinone plastoquinone (complex I) - - - 4.337e-197 655.0
HFD2_k127_1201277_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 529.0
HFD2_k127_1201277_2 Proton-conducting membrane transporter K12141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 388.0
HFD2_k127_1201277_3 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 367.0
HFD2_k127_1201277_4 Hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000000000002491 215.0
HFD2_k127_1201277_5 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000009976 225.0
HFD2_k127_1216370_0 homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0 1030.0
HFD2_k127_1216370_1 COGs COG4299 conserved - - - 1.495e-195 617.0
HFD2_k127_1216370_10 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000138 301.0
HFD2_k127_1216370_11 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000001386 269.0
HFD2_k127_1216370_12 PFAM SMP-30 Gluconolaconase LRE-like region K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000002046 226.0
HFD2_k127_1216370_13 heme-binding domain, Pirellula Verrucomicrobium type - - - 0.00000000000000000000000000000000000000000000000002183 189.0
HFD2_k127_1216370_14 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000007075 156.0
HFD2_k127_1216370_15 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000001711 85.0
HFD2_k127_1216370_16 - - - - 0.0000000634 59.0
HFD2_k127_1216370_17 helix_turn_helix, Lux Regulon - - - 0.00000008941 58.0
HFD2_k127_1216370_2 Putative collagen-binding domain of a collagenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 607.0
HFD2_k127_1216370_3 cytochrome C peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 559.0
HFD2_k127_1216370_4 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 353.0
HFD2_k127_1216370_5 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000697 347.0
HFD2_k127_1216370_6 Belongs to the SUA5 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 344.0
HFD2_k127_1216370_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 342.0
HFD2_k127_1216370_8 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 291.0
HFD2_k127_1216370_9 PFAM peptidase M19 renal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 306.0
HFD2_k127_1217489_0 Carboxypeptidase regulatory-like domain - - - 0.0 1345.0
HFD2_k127_1217489_1 protocatechuate 3,4-dioxygenase activity - - - 0.0 1330.0
HFD2_k127_1217489_10 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005336 536.0
HFD2_k127_1217489_11 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 407.0
HFD2_k127_1217489_12 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 395.0
HFD2_k127_1217489_13 Oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 369.0
HFD2_k127_1217489_14 exo-alpha-(2->6)-sialidase activity K01186 - 3.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 361.0
HFD2_k127_1217489_15 gluconolactonase activity K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 357.0
HFD2_k127_1217489_16 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 350.0
HFD2_k127_1217489_17 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 333.0
HFD2_k127_1217489_18 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 344.0
HFD2_k127_1217489_19 TfuA-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 319.0
HFD2_k127_1217489_2 Protein export membrane protein - - - 0.0 1057.0
HFD2_k127_1217489_20 Trehalose utilisation K09992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 310.0
HFD2_k127_1217489_21 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 304.0
HFD2_k127_1217489_22 Xylose isomerase-like TIM barrel K03079 - 5.1.3.22 0.000000000000000000000000000000000000000000000000000000000000000000111 242.0
HFD2_k127_1217489_23 PFAM Integrase catalytic region - - - 0.00000000000000000000000000000000000000000000000000000002603 205.0
HFD2_k127_1217489_24 PRC-barrel domain - - - 0.00000000000000000000000000000000000000000000000000004202 191.0
HFD2_k127_1217489_25 Integrase core domain - - - 0.00000000000000000000000000000000000000000000000001455 190.0
HFD2_k127_1217489_26 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000000000006275 176.0
HFD2_k127_1217489_27 xylan catabolic process - - - 0.000000000000000000000000000000000000002545 156.0
HFD2_k127_1217489_28 Outer membrane efflux protein - - - 0.00000000000000000000000000000001037 142.0
HFD2_k127_1217489_3 Carboxypeptidase regulatory-like domain - - - 5.316e-320 1018.0
HFD2_k127_1217489_30 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000001573 114.0
HFD2_k127_1217489_31 Transposase IS66 family K18320 - - 0.0000000000000000000002115 103.0
HFD2_k127_1217489_32 Histidine kinase - - - 0.0000000000000000002804 93.0
HFD2_k127_1217489_33 PFAM transposase IS116 IS110 IS902 family protein - - - 0.000000003532 62.0
HFD2_k127_1217489_34 - - - - 0.0000004144 53.0
HFD2_k127_1217489_35 PFAM Integrase catalytic region - - - 0.0001124 47.0
HFD2_k127_1217489_4 PFAM Uncharacterised BCR, COG1649 - - - 8.129e-297 925.0
HFD2_k127_1217489_5 Parallel beta-helix repeats - - - 1.06e-272 852.0
HFD2_k127_1217489_6 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 4.738e-223 721.0
HFD2_k127_1217489_7 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 648.0
HFD2_k127_1217489_8 protocatechuate 3,4-dioxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 580.0
HFD2_k127_1217489_9 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 566.0
HFD2_k127_124143_0 transport - - - 1.376e-256 827.0
HFD2_k127_124143_1 TonB-dependent receptor - - - 7.424e-256 826.0
HFD2_k127_124143_2 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 572.0
HFD2_k127_124143_3 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 339.0
HFD2_k127_124143_4 - - - - 0.00000000000000000000000000000000000000000000000001217 187.0
HFD2_k127_124143_5 GYD domain - - - 0.00000000000000000000000000000000000000000000008754 170.0
HFD2_k127_124143_6 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000003008 147.0
HFD2_k127_1253524_0 ABC transporter transmembrane K18889 - - 2.967e-215 675.0
HFD2_k127_1253524_1 SMART tyrosine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 579.0
HFD2_k127_1253524_2 Curli production assembly/transport component CsgG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 423.0
HFD2_k127_1253524_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000003012 184.0
HFD2_k127_1432067_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1083.0
HFD2_k127_1432067_1 cystathionine gamma-synthase activity K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 6.224e-198 636.0
HFD2_k127_1432067_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 317.0
HFD2_k127_1432067_11 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000168 264.0
HFD2_k127_1432067_12 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007712 245.0
HFD2_k127_1432067_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009859 514.0
HFD2_k127_1432067_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 490.0
HFD2_k127_1432067_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 493.0
HFD2_k127_1432067_5 excinuclease ABC activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007346 473.0
HFD2_k127_1432067_6 HlyD family secretion protein K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008063 457.0
HFD2_k127_1432067_7 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 405.0
HFD2_k127_1432067_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007155 385.0
HFD2_k127_1432067_9 COGs COG4299 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 375.0
HFD2_k127_1462438_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0 1606.0
HFD2_k127_1462438_1 PFAM aminotransferase, class I K00812 - 2.6.1.1 5.217e-208 651.0
HFD2_k127_1462438_16 Type ii and iii secretion system protein - - - 0.00000000006286 75.0
HFD2_k127_1462438_17 - - - - 0.00000000008905 68.0
HFD2_k127_1462438_2 Sulfatase - - - 1.879e-199 632.0
HFD2_k127_1462438_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 404.0
HFD2_k127_1462438_4 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 366.0
HFD2_k127_1462438_5 Phosphomannose isomerase type I K01809 - 5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 298.0
HFD2_k127_1462438_6 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001065 263.0
HFD2_k127_1462438_7 Macrocin-O-methyltransferase (TylF) - - - 0.0000000000000000000000000000000000000000008503 172.0
HFD2_k127_1462438_9 - - - - 0.00000000000000000000000000002806 121.0
HFD2_k127_1479115_0 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 3.787e-310 964.0
HFD2_k127_1479115_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.67e-239 750.0
HFD2_k127_1479115_10 major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005695 561.0
HFD2_k127_1479115_11 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 525.0
HFD2_k127_1479115_12 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 537.0
HFD2_k127_1479115_13 epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 481.0
HFD2_k127_1479115_14 Zn peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 460.0
HFD2_k127_1479115_15 acetamidase formamidase K01455 - 3.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 452.0
HFD2_k127_1479115_16 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01707 - 4.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 431.0
HFD2_k127_1479115_17 PFAM Squalene phytoene synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 441.0
HFD2_k127_1479115_18 TIGRFAM TonB family K03832 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 374.0
HFD2_k127_1479115_19 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 369.0
HFD2_k127_1479115_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 4.604e-228 712.0
HFD2_k127_1479115_20 MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002611 243.0
HFD2_k127_1479115_21 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000004906 206.0
HFD2_k127_1479115_23 - - - - 0.000000000000000000000000000000000000000000000000001246 188.0
HFD2_k127_1479115_24 cell redox homeostasis K03671 - - 0.0000000000000000000000000000000000000001921 170.0
HFD2_k127_1479115_25 Preprotein translocase, YajC K03210 - - 0.0000000000000000000000000000000003502 133.0
HFD2_k127_1479115_26 Phosphorylase superfamily - - - 0.0000000002327 73.0
HFD2_k127_1479115_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01706 - 4.2.1.40 4.47e-220 689.0
HFD2_k127_1479115_4 protocatechuate 3,4-dioxygenase activity - - - 2.961e-219 701.0
HFD2_k127_1479115_5 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 617.0
HFD2_k127_1479115_6 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 581.0
HFD2_k127_1479115_7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 570.0
HFD2_k127_1479115_8 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 560.0
HFD2_k127_1479115_9 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 557.0
HFD2_k127_1502404_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.0 1102.0
HFD2_k127_1502404_1 Protein of unknown function (DUF1553) - - - 0.0 1087.0
HFD2_k127_1502404_10 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 589.0
HFD2_k127_1502404_11 Histidine kinase K20971,K20974 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 571.0
HFD2_k127_1502404_12 Arylsulfatase a K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 528.0
HFD2_k127_1502404_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 518.0
HFD2_k127_1502404_14 Sodium/calcium exchanger protein K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 434.0
HFD2_k127_1502404_15 COG1073 Hydrolases of the alpha beta superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 435.0
HFD2_k127_1502404_16 Oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 371.0
HFD2_k127_1502404_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 344.0
HFD2_k127_1502404_19 4Fe-4S binding domain K08358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 323.0
HFD2_k127_1502404_2 Alpha-L-fucosidase K01206 - 3.2.1.51 1.026e-254 797.0
HFD2_k127_1502404_20 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 318.0
HFD2_k127_1502404_21 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 328.0
HFD2_k127_1502404_22 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000938 281.0
HFD2_k127_1502404_23 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001427 273.0
HFD2_k127_1502404_24 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008109 297.0
HFD2_k127_1502404_25 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K04013,K15876 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001924 269.0
HFD2_k127_1502404_26 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007612 261.0
HFD2_k127_1502404_27 Belongs to the TPP enzyme family K01652 GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000002203 244.0
HFD2_k127_1502404_28 Integral membrane protein (intg_mem_TP0381) - - - 0.0000000000000000000000000000000000000000000000000000000000001609 221.0
HFD2_k127_1502404_29 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000000000000000000000000000001003 195.0
HFD2_k127_1502404_3 Protein of unknown function (DUF1501) - - - 5.826e-239 746.0
HFD2_k127_1502404_30 Histidine kinase-like ATPase domain - - - 0.000000000000000000000000000000000000000000000000000001837 203.0
HFD2_k127_1502404_31 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000001188 186.0
HFD2_k127_1502404_32 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000000000000000000000000006526 177.0
HFD2_k127_1502404_33 Thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000001542 177.0
HFD2_k127_1502404_34 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000004174 158.0
HFD2_k127_1502404_35 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000002179 159.0
HFD2_k127_1502404_36 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000001199 150.0
HFD2_k127_1502404_37 PEP-CTERM motif - - - 0.00000000000000000000000000000000114 138.0
HFD2_k127_1502404_38 - - - - 0.000000000000000000000000003765 116.0
HFD2_k127_1502404_39 Phage shock protein C, PspC K03973 - - 0.0000000000000000000000000181 111.0
HFD2_k127_1502404_4 inositol 2-dehydrogenase activity - - - 3.204e-223 698.0
HFD2_k127_1502404_40 Surface antigen - - - 0.000000000000001916 89.0
HFD2_k127_1502404_41 Pfam:DUF2305 - - - 0.000000000000002098 86.0
HFD2_k127_1502404_42 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.00000000001139 75.0
HFD2_k127_1502404_5 PFAM ABC transporter K03466,K06147,K18890 - - 1.145e-210 671.0
HFD2_k127_1502404_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 3.715e-197 656.0
HFD2_k127_1502404_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 610.0
HFD2_k127_1502404_8 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 601.0
HFD2_k127_1502404_9 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 585.0
HFD2_k127_1519369_0 TonB-dependent receptor - - - 7.555e-217 714.0
HFD2_k127_1519369_1 serine-type peptidase activity K06978,K21105 - 3.1.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 377.0
HFD2_k127_1519369_2 Protein of unknown function (DUF1592) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 327.0
HFD2_k127_1519369_3 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000000005849 218.0
HFD2_k127_1519369_4 Thioesterase domain - - - 0.00000000000000000000000000000000000000000000003957 173.0
HFD2_k127_1519369_5 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000004982 148.0
HFD2_k127_1519369_6 Leucine Rich repeat - - - 0.0000000000000000000000000000000000000766 162.0
HFD2_k127_1519369_7 Leucine Rich repeat - - - 0.0000000000000000000000000005285 125.0
HFD2_k127_1519369_8 Belongs to the P-Pant transferase superfamily K06133 - - 0.00000000000000000002829 102.0
HFD2_k127_1530640_0 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 626.0
HFD2_k127_1530640_1 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 628.0
HFD2_k127_1530640_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 574.0
HFD2_k127_1530640_3 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 512.0
HFD2_k127_1530640_4 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000008365 216.0
HFD2_k127_1530640_5 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000004623 169.0
HFD2_k127_1530640_6 - - - - 0.000000000000000000000000000000000000001171 164.0
HFD2_k127_1530640_7 response regulator - - - 0.000000000000000000000000000000000000001377 150.0
HFD2_k127_1530640_8 Domain of unknown function (DUF4154) - - - 0.000000000000000000000000000001241 136.0
HFD2_k127_1530640_9 COG2198 FOG HPt domain K20976 - - 0.000006032 54.0
HFD2_k127_153878_0 Beta-propeller repeat - - - 0.0 1157.0
HFD2_k127_153878_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 3.428e-270 855.0
HFD2_k127_153878_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.817e-208 657.0
HFD2_k127_153878_3 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007579 492.0
HFD2_k127_153878_4 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 375.0
HFD2_k127_153878_5 Bacitracin resistance protein BacA K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 355.0
HFD2_k127_153878_6 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004487 269.0
HFD2_k127_153878_7 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000001244 193.0
HFD2_k127_153878_8 protein with SCP PR1 domains - - - 0.000000000000000000000000003311 119.0
HFD2_k127_1542703_0 Pyridoxal-phosphate dependent enzyme K06001 - 4.2.1.20 6.839e-241 760.0
HFD2_k127_1542703_1 polygalacturonase activity - - - 0.00000000000000000000000000000000000000000001028 170.0
HFD2_k127_1542703_2 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.00000000000000004502 87.0
HFD2_k127_1558013_0 Hypothetical glycosyl hydrolase 6 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 537.0
HFD2_k127_1558013_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 353.0
HFD2_k127_1558013_2 BON domain - - - 0.0000000000000000000000000000000000000000000000000000000000000007784 224.0
HFD2_k127_1558013_3 - - - - 0.000000000000000000000000000000000000000000000000000000000007098 213.0
HFD2_k127_1558013_4 TIGRFAM cytochrome c nitrate reductase, small subunit K15876 - - 0.00000000000000000000000000000000000000000000003298 173.0
HFD2_k127_1558013_5 Domain of unknown function (DUF4142) K08995 - - 0.0000000000000000000000000000000000008198 147.0
HFD2_k127_1565506_0 ATPase BadF BadG BcrA BcrD type - - - 6.659e-318 1003.0
HFD2_k127_1565506_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 1.092e-208 673.0
HFD2_k127_1565506_10 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000005346 207.0
HFD2_k127_1565506_11 dUTPase K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000002456 225.0
HFD2_k127_1565506_12 Belongs to the globin family - - - 0.0000000000000000000000000000000000000000205 158.0
HFD2_k127_1565506_13 abc transporter K02003 - - 0.0000000000000000000000000000000000000426 146.0
HFD2_k127_1565506_14 Bacterial PH domain - - - 0.000000000000000000000000000000000003255 142.0
HFD2_k127_1565506_15 Belongs to the globin family K05916 - 1.14.12.17 0.00000000000000000000000000003634 124.0
HFD2_k127_1565506_16 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.000000000000000000000000002173 118.0
HFD2_k127_1565506_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 608.0
HFD2_k127_1565506_3 PFAM NADH flavin oxidoreductase NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 499.0
HFD2_k127_1565506_4 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 492.0
HFD2_k127_1565506_5 PFAM Chlorite dismutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 379.0
HFD2_k127_1565506_6 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 371.0
HFD2_k127_1565506_7 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000005021 273.0
HFD2_k127_1565506_8 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000001141 229.0
HFD2_k127_1565506_9 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000006356 223.0
HFD2_k127_1576475_0 chlorophyll binding - - - 0.0 1050.0
HFD2_k127_1576475_1 Carboxypeptidase regulatory-like domain - - - 0.0 1032.0
HFD2_k127_1576475_10 Beta-lactamase class C K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 484.0
HFD2_k127_1576475_11 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 420.0
HFD2_k127_1576475_12 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000002913 225.0
HFD2_k127_1576475_13 23S rRNA (guanine(2445)-N(2))-methyltransferase activity K21515 - 2.1.1.209 0.0000000000000000000000000000000000000000000000000000000000000041 222.0
HFD2_k127_1576475_14 Tellurite resistance protein tehB K03647,K16868 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.265 0.000000000000000000000000000000000000000000000000000000000002017 212.0
HFD2_k127_1576475_15 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000000000001105 155.0
HFD2_k127_1576475_16 Cation transport regulator - - - 0.00000000000000000000001197 113.0
HFD2_k127_1576475_17 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000006467 77.0
HFD2_k127_1576475_2 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 4.666e-304 939.0
HFD2_k127_1576475_3 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.799e-279 879.0
HFD2_k127_1576475_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 1.274e-239 751.0
HFD2_k127_1576475_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 6.725e-206 645.0
HFD2_k127_1576475_6 Vault protein inter-alpha-trypsin domain K07114 - - 9.026e-205 662.0
HFD2_k127_1576475_7 peptidase dimerisation domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 563.0
HFD2_k127_1576475_8 Glycosyl transferase family group 2 K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 554.0
HFD2_k127_1576475_9 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 512.0
HFD2_k127_1631246_0 Alpha-glucan phosphorylase K00688 - 2.4.1.1 0.0 1136.0
HFD2_k127_1631246_1 Methyltransferase, chemotaxis proteins K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 342.0
HFD2_k127_1631246_10 polygalacturonase activity - - - 0.0000007614 63.0
HFD2_k127_1631246_12 COG1413 FOG HEAT repeat K22221 - - 0.0003578 51.0
HFD2_k127_1631246_2 Oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000136 257.0
HFD2_k127_1631246_3 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000312 231.0
HFD2_k127_1631246_4 peptidase S1 and S6, chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000001497 205.0
HFD2_k127_1631246_5 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000002223 164.0
HFD2_k127_1631246_6 response regulator - - - 0.0000000000000000000000000000000000005207 144.0
HFD2_k127_1631246_7 phosphorelay signal transduction system - - - 0.000000000000000000000000004052 115.0
HFD2_k127_1631246_8 acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000003594 108.0
HFD2_k127_1631246_9 S-layer homology domain K01181,K01186,K12373,K20276 - 3.2.1.18,3.2.1.52,3.2.1.8 0.000000000000367 83.0
HFD2_k127_1691889_0 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 413.0
HFD2_k127_1691889_1 MlrC C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008985 343.0
HFD2_k127_1691889_2 PFAM von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000744 278.0
HFD2_k127_1691889_3 - - - - 0.000000000000000000000000000000000000000000192 168.0
HFD2_k127_1705335_0 Carboxypeptidase regulatory-like domain - - - 4.289e-304 977.0
HFD2_k127_1705335_1 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 1.348e-269 841.0
HFD2_k127_1705335_10 FR47-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 305.0
HFD2_k127_1705335_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 292.0
HFD2_k127_1705335_12 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000007578 246.0
HFD2_k127_1705335_13 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000164 247.0
HFD2_k127_1705335_14 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000000000000000002564 199.0
HFD2_k127_1705335_16 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000002582 170.0
HFD2_k127_1705335_17 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000006518 163.0
HFD2_k127_1705335_18 - - - - 0.000000000000000000000000000000000002812 142.0
HFD2_k127_1705335_19 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000004511 140.0
HFD2_k127_1705335_2 Domain of unknown function (DUF4331) - - - 2.093e-232 728.0
HFD2_k127_1705335_21 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000001932 121.0
HFD2_k127_1705335_22 beta-galactosidase activity - - - 0.000000000000000004487 99.0
HFD2_k127_1705335_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 580.0
HFD2_k127_1705335_4 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 490.0
HFD2_k127_1705335_5 Belongs to the NiCoT transporter (TC 2.A.52) family K08970 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 480.0
HFD2_k127_1705335_6 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 416.0
HFD2_k127_1705335_7 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 369.0
HFD2_k127_1705335_8 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 350.0
HFD2_k127_1705335_9 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 317.0
HFD2_k127_1720301_0 carboxylic acid catabolic process K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 529.0
HFD2_k127_1720301_1 TIGRFAM membrane-bound dehydrogenase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 503.0
HFD2_k127_1720301_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 404.0
HFD2_k127_1720301_3 NlpC/P60 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009159 364.0
HFD2_k127_1720301_4 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 326.0
HFD2_k127_1720301_5 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000879 186.0
HFD2_k127_1748575_0 Dihydrodipicolinate synthetase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 496.0
HFD2_k127_1748575_1 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009523 477.0
HFD2_k127_1748575_10 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000000000000000001483 160.0
HFD2_k127_1748575_12 Protein of unknown function (DUF3106) - - - 0.0003623 51.0
HFD2_k127_1748575_2 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008464 374.0
HFD2_k127_1748575_3 peptidase activity, acting on L-amino acid peptides K09607 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 351.0
HFD2_k127_1748575_4 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 310.0
HFD2_k127_1748575_5 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 286.0
HFD2_k127_1748575_6 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006772 267.0
HFD2_k127_1748575_7 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000001244 263.0
HFD2_k127_1748575_8 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003539 250.0
HFD2_k127_1748575_9 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000000000000000000008557 217.0
HFD2_k127_1816960_0 PQQ-like domain K00114 - 1.1.2.8 5.042e-256 812.0
HFD2_k127_1816960_1 endopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 578.0
HFD2_k127_1816960_10 Protein of unknown function (DUF3616) - - - 0.00000000000000000000000000000000000000000000000000000000000001463 228.0
HFD2_k127_1816960_11 PFAM secretion protein HlyD family protein K02005,K02022 - - 0.00000000000000000000000000000000000000000000005868 195.0
HFD2_k127_1816960_13 Outer membrane efflux protein K12340 - - 0.00000000000000000000000002069 111.0
HFD2_k127_1816960_2 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 555.0
HFD2_k127_1816960_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00066 - 1.1.1.132 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 533.0
HFD2_k127_1816960_4 Glycosyl transferase family group 2 K19290 - 2.4.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 519.0
HFD2_k127_1816960_5 PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 382.0
HFD2_k127_1816960_6 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 374.0
HFD2_k127_1816960_7 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 343.0
HFD2_k127_1816960_8 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 326.0
HFD2_k127_1816960_9 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000002809 252.0
HFD2_k127_1821300_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 504.0
HFD2_k127_1821300_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 481.0
HFD2_k127_1821300_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 432.0
HFD2_k127_1821300_3 transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 409.0
HFD2_k127_1821300_4 carbohydrate transport K02027,K10236 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 343.0
HFD2_k127_1821300_5 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004568 269.0
HFD2_k127_1821300_6 COG1055 Na H antiporter NhaD and related arsenite permeases - - - 0.00000000000000000000000000000001775 130.0
HFD2_k127_1821300_7 alpha-L-rhamnosidase - - - 0.0008146 43.0
HFD2_k127_1829509_0 transport - - - 0.0 1476.0
HFD2_k127_1829509_1 Carboxypeptidase regulatory-like domain - - - 7.657e-288 924.0
HFD2_k127_1829509_10 efflux transmembrane transporter activity - - - 0.000005713 58.0
HFD2_k127_1829509_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 5.642e-250 779.0
HFD2_k127_1829509_3 Pfam:DUF303 K05970 - 3.1.1.53 9.825e-205 647.0
HFD2_k127_1829509_4 D-mannonate dehydratase (UxuA) K01686 - 4.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 543.0
HFD2_k127_1829509_5 transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 390.0
HFD2_k127_1829509_6 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 310.0
HFD2_k127_1829509_7 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000366 296.0
HFD2_k127_1829509_8 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000001822 184.0
HFD2_k127_1829509_9 SMART Integrin alpha beta-propellor repeat protein - - - 0.00000000001913 69.0
HFD2_k127_184016_0 Carboxypeptidase regulatory-like domain - - - 1.406e-300 958.0
HFD2_k127_184016_1 Tetratricopeptide repeat - - - 4.309e-246 771.0
HFD2_k127_184016_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 9.528e-225 700.0
HFD2_k127_184016_3 Fungal family of unknown function (DUF1776) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 393.0
HFD2_k127_184016_4 BNR repeat-like domain K05989 - 3.2.1.40 0.00000000000000000000000000000000000000000000000003871 201.0
HFD2_k127_184016_5 Carboxypeptidase regulatory-like domain - - - 0.000000000000007373 87.0
HFD2_k127_184016_6 Cupin 2, conserved barrel domain protein - - - 0.000001098 61.0
HFD2_k127_184016_7 - K01865 - 5.4.4.1 0.000007772 53.0
HFD2_k127_18602_0 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 3.849e-267 837.0
HFD2_k127_18602_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.555e-213 670.0
HFD2_k127_18602_2 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 458.0
HFD2_k127_18602_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 454.0
HFD2_k127_18602_4 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 392.0
HFD2_k127_18602_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000111 245.0
HFD2_k127_18602_6 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000008342 192.0
HFD2_k127_1876281_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 1.161e-277 859.0
HFD2_k127_1876281_1 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 579.0
HFD2_k127_1876281_11 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000001013 79.0
HFD2_k127_1876281_12 GAF domain - - - 0.00000004115 64.0
HFD2_k127_1876281_2 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 509.0
HFD2_k127_1876281_3 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 457.0
HFD2_k127_1876281_4 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 376.0
HFD2_k127_1876281_5 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 355.0
HFD2_k127_1876281_6 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 357.0
HFD2_k127_1876281_7 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001382 281.0
HFD2_k127_1876281_8 Memo-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000422 246.0
HFD2_k127_1876281_9 - - - - 0.00000000000000000000000000000000000000000002378 165.0
HFD2_k127_188712_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1103.0
HFD2_k127_188712_1 Carboxyl transferase domain - - - 4.623e-265 826.0
HFD2_k127_188712_10 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 418.0
HFD2_k127_188712_11 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 364.0
HFD2_k127_188712_12 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002657 285.0
HFD2_k127_188712_14 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000007994 196.0
HFD2_k127_188712_15 Outer membrane protein (OmpH-like) K06142 - - 0.00000000000000000000000000000000000000000000001124 176.0
HFD2_k127_188712_16 - - - - 0.000000000000000000000000000000000000000000001202 188.0
HFD2_k127_188712_17 - - - - 0.00000000000000000000000000000000000000000008633 161.0
HFD2_k127_188712_18 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000000506 159.0
HFD2_k127_188712_19 - - - - 0.000000000000000000000000000000000000000003921 165.0
HFD2_k127_188712_2 Acyclic terpene utilisation family protein AtuA - - - 2.299e-245 763.0
HFD2_k127_188712_20 RNA recognition motif - - - 0.0000000000000000000000000000000000002207 142.0
HFD2_k127_188712_21 Cytochrome c K02720 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.0000000000000000000000000007599 121.0
HFD2_k127_188712_3 MacB-like periplasmic core domain - - - 9.281e-203 659.0
HFD2_k127_188712_4 arylsulfatase activity - - - 5.14e-198 627.0
HFD2_k127_188712_5 PQQ-like domain K00117 - 1.1.5.2 5.432e-197 632.0
HFD2_k127_188712_6 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 595.0
HFD2_k127_188712_7 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 584.0
HFD2_k127_188712_8 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 578.0
HFD2_k127_188712_9 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 483.0
HFD2_k127_1921549_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 583.0
HFD2_k127_1921549_1 thiosulfate sulfurtransferase activity K01011 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 467.0
HFD2_k127_1921549_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 365.0
HFD2_k127_1921549_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 329.0
HFD2_k127_1921549_4 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000002719 152.0
HFD2_k127_1925970_0 PFAM Amidase - - - 1.519e-229 722.0
HFD2_k127_1925970_1 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 520.0
HFD2_k127_1925970_10 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000005144 247.0
HFD2_k127_1925970_11 dCMP deaminase activity K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000005847 233.0
HFD2_k127_1925970_12 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000002543 158.0
HFD2_k127_1925970_13 Uncharacterized ACR, COG1430 - - - 0.00000000000000000000000000000004814 130.0
HFD2_k127_1925970_2 Mo-co oxidoreductase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 481.0
HFD2_k127_1925970_3 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 424.0
HFD2_k127_1925970_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 408.0
HFD2_k127_1925970_5 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648 372.0
HFD2_k127_1925970_6 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 344.0
HFD2_k127_1925970_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009949 340.0
HFD2_k127_1925970_8 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 327.0
HFD2_k127_1925970_9 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 316.0
HFD2_k127_1946871_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 521.0
HFD2_k127_1946871_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 531.0
HFD2_k127_1946871_2 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008533 513.0
HFD2_k127_1946871_3 Domain of unknown function (DUF3488) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 376.0
HFD2_k127_1946871_4 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 352.0
HFD2_k127_1946871_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 318.0
HFD2_k127_1946871_6 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000483 244.0
HFD2_k127_1946871_7 Ham1 family K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000005673 250.0
HFD2_k127_1957161_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 398.0
HFD2_k127_1957161_1 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000002318 158.0
HFD2_k127_1957161_3 Periplasmic component of the Tol biopolymer transport K03641 - - 0.000000004815 67.0
HFD2_k127_1958313_0 Carboxypeptidase regulatory-like domain - - - 0.0 1373.0
HFD2_k127_1958313_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 8.872e-319 983.0
HFD2_k127_1958313_10 helicase activity - - - 0.0000000001283 66.0
HFD2_k127_1958313_11 PIN domain - - - 0.000000003845 63.0
HFD2_k127_1958313_2 Protein of unknown function (DUF1501) - - - 5.104e-210 658.0
HFD2_k127_1958313_3 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 632.0
HFD2_k127_1958313_4 Arylsulfatase K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 488.0
HFD2_k127_1958313_5 DEAD DEAH box helicase domain protein K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 501.0
HFD2_k127_1958313_6 O-methyltransferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001367 277.0
HFD2_k127_1958313_7 Protein of unknown function, DUF481 - - - 0.0000000000000000000000000000000000000000000000000000000000000000006656 241.0
HFD2_k127_1958313_8 ribonuclease inhibitor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001599 245.0
HFD2_k127_1958313_9 Ferredoxin - - - 0.0000000000000000001131 104.0
HFD2_k127_1958668_0 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 526.0
HFD2_k127_1958668_1 type VI secretion protein K11900,K11901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 436.0
HFD2_k127_1958668_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 344.0
HFD2_k127_1958668_3 Kelch motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 305.0
HFD2_k127_1958668_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 299.0
HFD2_k127_1958668_5 FMN-dependent dehydrogenase K16422 - 1.1.3.46 0.000000000000000000000000000000000000000000000000000000000000000000003894 250.0
HFD2_k127_1958668_6 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000002064 211.0
HFD2_k127_1958668_7 FMN-dependent dehydrogenase K00101 - 1.1.2.3 0.00000000000000000000000000000000000000000000000000001465 209.0
HFD2_k127_1958668_8 bacterial OsmY and nodulation domain K04065 - - 0.0002383 48.0
HFD2_k127_1970183_0 Tricorn protease PDZ domain K08676 - - 0.0 1348.0
HFD2_k127_1970183_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1173.0
HFD2_k127_1970183_10 e3 binding domain K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007844 386.0
HFD2_k127_1970183_11 Zinc-binding dehydrogenase K00001,K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 370.0
HFD2_k127_1970183_12 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001578 293.0
HFD2_k127_1970183_13 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000003166 242.0
HFD2_k127_1970183_14 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000005051 237.0
HFD2_k127_1970183_15 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000005324 238.0
HFD2_k127_1970183_16 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000001649 213.0
HFD2_k127_1970183_17 Protein of unknown function (DUF1572) - - - 0.00000000000000000000000000000000000000004658 162.0
HFD2_k127_1970183_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 1.422e-295 924.0
HFD2_k127_1970183_3 PFAM Glycosyl transferase family 2 - - - 1.793e-289 895.0
HFD2_k127_1970183_4 Belongs to the glycosyl hydrolase 67 family - - - 3.31e-276 872.0
HFD2_k127_1970183_5 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 2.421e-234 734.0
HFD2_k127_1970183_6 transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 587.0
HFD2_k127_1970183_7 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 450.0
HFD2_k127_1970183_8 PFAM Surface antigen variable number K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 436.0
HFD2_k127_1970183_9 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 385.0
HFD2_k127_2002286_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00956 - 2.7.7.4 1.446e-199 637.0
HFD2_k127_2012734_0 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 574.0
HFD2_k127_2012734_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 479.0
HFD2_k127_2012734_10 - - - - 0.000959 47.0
HFD2_k127_2012734_2 LysR substrate binding domain K03717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 409.0
HFD2_k127_2012734_3 membrane protein, TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 393.0
HFD2_k127_2012734_4 Belongs to the HpcH HpaI aldolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 305.0
HFD2_k127_2012734_5 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 301.0
HFD2_k127_2012734_6 acetylesterase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 289.0
HFD2_k127_2012734_7 COG COG3119 Arylsulfatase A and related enzymes - - - 0.000000000000000000000000000000000000000000000000005776 189.0
HFD2_k127_2012734_8 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000006162 140.0
HFD2_k127_2014807_0 BNR repeat-like domain K05989 - 3.2.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009909 554.0
HFD2_k127_2014807_1 - - - - 0.0000000000000000000000000000000000000000000000000005321 201.0
HFD2_k127_2014807_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000001784 102.0
HFD2_k127_2014807_3 nuclease activity - - - 0.0000000004471 67.0
HFD2_k127_2022923_0 MacB-like periplasmic core domain - - - 0.0 1317.0
HFD2_k127_2022923_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 2.021e-203 643.0
HFD2_k127_2022923_10 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000000000002201 198.0
HFD2_k127_2022923_11 Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000000000003136 174.0
HFD2_k127_2022923_12 - - - - 0.0000000000000000000000000000003087 141.0
HFD2_k127_2022923_13 - - - - 0.00000000000000000001531 96.0
HFD2_k127_2022923_14 peptidase M6 immune inhibitor A K09607 - - 0.0000000000000002691 80.0
HFD2_k127_2022923_15 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000003517 69.0
HFD2_k127_2022923_16 Glucose / Sorbosone dehydrogenase - - - 0.0000000003271 72.0
HFD2_k127_2022923_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 606.0
HFD2_k127_2022923_3 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 580.0
HFD2_k127_2022923_4 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 491.0
HFD2_k127_2022923_5 Dihydrodipicolinate synthetase family K18123 - 4.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 494.0
HFD2_k127_2022923_6 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 437.0
HFD2_k127_2022923_7 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007199 277.0
HFD2_k127_2022923_8 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001005 261.0
HFD2_k127_2022923_9 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000004482 231.0
HFD2_k127_2023177_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 5.835e-312 969.0
HFD2_k127_2023177_1 Carboxypeptidase regulatory-like domain - - - 1.709e-279 898.0
HFD2_k127_2023177_10 Bacterial export proteins, family 1 K02421 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001237 287.0
HFD2_k127_2023177_11 basal body rod protein K02391,K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006331 278.0
HFD2_k127_2023177_12 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0000000000000000000000000000000000000000000000000000000000000000001254 250.0
HFD2_k127_2023177_13 Chaperone for flagella basal body P-ring formation K02386 - - 0.00000000000000000000000000000000000000000000000000006726 198.0
HFD2_k127_2023177_14 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000000000001055 157.0
HFD2_k127_2023177_15 Flagellar protein FliS K02422 - - 0.0000000000000000000000000000005157 127.0
HFD2_k127_2023177_16 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000634 108.0
HFD2_k127_2023177_17 Type III flagellar switch regulator (C-ring) FliN C-term K02417 - - 0.00000000000000000000006577 105.0
HFD2_k127_2023177_18 Rod binding protein - - - 0.0000000000000001257 82.0
HFD2_k127_2023177_19 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.000000000007917 76.0
HFD2_k127_2023177_2 arylsulfatase activity K01130,K01134 - 3.1.6.1,3.1.6.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 613.0
HFD2_k127_2023177_20 Flagellar biosynthetic protein FliQ K02420 - - 0.0000000001514 64.0
HFD2_k127_2023177_22 Type III flagellar switch regulator (C-ring) FliN C-term K02417 - - 0.000000134 56.0
HFD2_k127_2023177_23 flagellar K02418 - - 0.0000002742 59.0
HFD2_k127_2023177_25 PFAM Flagellar protein FlaG protein K06603 - - 0.0000415 51.0
HFD2_k127_2023177_3 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 477.0
HFD2_k127_2023177_4 Flagellar basal body protein FlaE K02390 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 446.0
HFD2_k127_2023177_5 flagellar basal-body rod protein FlgG K02392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 438.0
HFD2_k127_2023177_6 FlhB HrpN YscU SpaS Family K02401 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 398.0
HFD2_k127_2023177_7 Plays a role in the flagellum-specific transport system K02419 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 337.0
HFD2_k127_2023177_8 TIGRFAM RNA polymerase sigma factor, FliA WhiG family K02405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 323.0
HFD2_k127_2023177_9 SRP54-type protein, GTPase domain K02404 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000191 292.0
HFD2_k127_2024202_0 Cytochrome c, class I - - - 1.024e-274 864.0
HFD2_k127_2024202_1 Protein of unknown function (DUF1501) - - - 2.122e-223 700.0
HFD2_k127_2024202_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 300.0
HFD2_k127_2024202_4 Anti-sigma-K factor rskA - - - 0.00000000000000000000000000000001987 135.0
HFD2_k127_2028674_0 Belongs to the PstS family K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 436.0
HFD2_k127_2028674_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 395.0
HFD2_k127_2028674_2 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 368.0
HFD2_k127_2028674_3 Phosphate transport system permease protein PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 363.0
HFD2_k127_2028674_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009334 342.0
HFD2_k127_2028674_5 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 312.0
HFD2_k127_2028674_6 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004161 255.0
HFD2_k127_2028674_7 Transcriptional regulatory protein, C terminal K02483,K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000008392 231.0
HFD2_k127_2028674_8 Putative porin - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000001419 64.0
HFD2_k127_2038319_0 Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008641 395.0
HFD2_k127_2038319_1 N-Acetylmuramoyl-L-alanine amidase K11066,K12287 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 331.0
HFD2_k127_2038319_2 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000199 130.0
HFD2_k127_2053777_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008527 439.0
HFD2_k127_2053777_1 type II secretion system K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002366 254.0
HFD2_k127_205996_0 Phosphoesterase family - - - 1.51e-233 741.0
HFD2_k127_205996_1 PFAM Major Facilitator Superfamily K08191 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 520.0
HFD2_k127_205996_10 Iron-containing alcohol dehydrogenase K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000000000000000000000000001661 255.0
HFD2_k127_205996_11 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000000000000000000000000000005325 226.0
HFD2_k127_205996_12 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000000000000000000000000000000000000000863 162.0
HFD2_k127_205996_13 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000002514 147.0
HFD2_k127_205996_15 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000000005513 134.0
HFD2_k127_205996_16 PFAM Uncharacterised BCR, COG1649 - - - 0.0000000000000000000000000004075 132.0
HFD2_k127_205996_17 heavy metal translocating P-type ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000000000000000001303 119.0
HFD2_k127_205996_18 - - - - 0.000000000000000000001333 99.0
HFD2_k127_205996_19 PAP2 superfamily - - - 0.000000000000000003407 96.0
HFD2_k127_205996_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 502.0
HFD2_k127_205996_20 - - - - 0.0000000000000007912 82.0
HFD2_k127_205996_21 RES - - - 0.00000000000000632 83.0
HFD2_k127_205996_3 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 486.0
HFD2_k127_205996_4 PFAM TonB-dependent Receptor Plug - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003322 394.0
HFD2_k127_205996_5 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 362.0
HFD2_k127_205996_6 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 336.0
HFD2_k127_205996_7 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 306.0
HFD2_k127_205996_9 Periplasmic or secreted lipoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006129 261.0
HFD2_k127_2062165_0 Cytochrome c - - - 0.0 1607.0
HFD2_k127_2062165_1 methyltransferase - - - 1.78e-207 654.0
HFD2_k127_2062165_10 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008432 359.0
HFD2_k127_2062165_11 cell redox homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000954 320.0
HFD2_k127_2062165_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 308.0
HFD2_k127_2062165_13 Periplasmic or secreted lipoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006966 246.0
HFD2_k127_2062165_14 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001786 251.0
HFD2_k127_2062165_15 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000007231 250.0
HFD2_k127_2062165_17 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000004753 233.0
HFD2_k127_2062165_18 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000001766 213.0
HFD2_k127_2062165_19 heme a metabolic process K02259,K03110 - - 0.0000000000000000000000000000000000000000000000000000000001322 214.0
HFD2_k127_2062165_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 544.0
HFD2_k127_2062165_20 SCO1/SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000001656 211.0
HFD2_k127_2062165_21 Domain of unknown function (DUF4280) - - - 0.0000000000000000000000000000000000000000000000000003272 195.0
HFD2_k127_2062165_22 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000000000000000000000000000000000000001951 185.0
HFD2_k127_2062165_23 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000002464 173.0
HFD2_k127_2062165_24 Protein of unknown function (DUF420) K08976 - - 0.0000000000000000000000000000000000000000001126 173.0
HFD2_k127_2062165_26 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000004742 150.0
HFD2_k127_2062165_28 COG NOG14600 non supervised orthologous group - - - 0.000000000000000000000003924 104.0
HFD2_k127_2062165_29 DSBA-like thioredoxin domain - - - 0.00000000000000387 85.0
HFD2_k127_2062165_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007655 542.0
HFD2_k127_2062165_31 Gram-negative bacterial TonB protein C-terminal - - - 0.0000002368 63.0
HFD2_k127_2062165_34 efflux transmembrane transporter activity - - - 0.0002984 50.0
HFD2_k127_2062165_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009645 459.0
HFD2_k127_2062165_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 441.0
HFD2_k127_2062165_6 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009537 398.0
HFD2_k127_2062165_7 Transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 391.0
HFD2_k127_2062165_8 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005495 368.0
HFD2_k127_2062165_9 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 365.0
HFD2_k127_2084734_0 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009198 306.0
HFD2_k127_2084734_1 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000001795 185.0
HFD2_k127_2084734_2 - - - - 0.000000000000000000000000000000000000000000001016 168.0
HFD2_k127_2084734_3 Fibronectin type III domain protein - - - 0.000000000000000000000000000000000000313 147.0
HFD2_k127_2090931_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 573.0
HFD2_k127_2091647_0 synthase K01719,K13542 - 2.1.1.107,4.2.1.75 6.399e-234 742.0
HFD2_k127_2091647_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 1.115e-206 652.0
HFD2_k127_2091647_2 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 436.0
HFD2_k127_2091647_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 412.0
HFD2_k127_2091647_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 296.0
HFD2_k127_2091647_5 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005554 276.0
HFD2_k127_2091647_6 Protein of unknown function (DUF2723) - - - 0.0000000000000000000000000000000735 142.0
HFD2_k127_2097664_0 - - - - 1.241e-279 871.0
HFD2_k127_2097664_1 peptidyl-tyrosine sulfation - - - 7.099e-201 641.0
HFD2_k127_2097664_2 Right handed beta helix region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 488.0
HFD2_k127_2097664_4 - - - - 0.000002544 52.0
HFD2_k127_2115559_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0 1412.0
HFD2_k127_2115559_1 Prolyl oligopeptidase family - - - 6.708e-254 802.0
HFD2_k127_2115559_10 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 509.0
HFD2_k127_2115559_11 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 494.0
HFD2_k127_2115559_12 TOBE domain K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 466.0
HFD2_k127_2115559_13 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 448.0
HFD2_k127_2115559_14 Binding-protein-dependent transport system inner membrane component K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 413.0
HFD2_k127_2115559_15 H( )-stimulated, divalent metal cation uptake system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 431.0
HFD2_k127_2115559_16 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 409.0
HFD2_k127_2115559_17 Binding-protein-dependent transport system inner membrane component K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 394.0
HFD2_k127_2115559_18 Enoyl-CoA hydratase/isomerase K01715,K07537 - 4.2.1.100,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007145 390.0
HFD2_k127_2115559_19 2-keto-3-deoxy-L-rhamnonate aldolase activity K00979,K01630,K02510 - 2.7.7.38,4.1.2.20,4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 345.0
HFD2_k127_2115559_2 PFAM Thiamine pyrophosphate K01652 - 2.2.1.6 4.471e-248 776.0
HFD2_k127_2115559_20 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001061 241.0
HFD2_k127_2115559_21 TIGRFAM TonB K03832 - - 0.00000000000000000000000000000000000000000000003668 179.0
HFD2_k127_2115559_3 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 5.374e-196 620.0
HFD2_k127_2115559_4 glycosyl transferase group 1 K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007877 598.0
HFD2_k127_2115559_5 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 576.0
HFD2_k127_2115559_6 AMP-binding enzyme C-terminal domain K00666,K20034 - 6.2.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 599.0
HFD2_k127_2115559_7 transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 574.0
HFD2_k127_2115559_8 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000991 561.0
HFD2_k127_2115559_9 Bacterial extracellular solute-binding protein K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 537.0
HFD2_k127_2122864_0 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 8.368e-309 961.0
HFD2_k127_2122864_1 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003181 273.0
HFD2_k127_2122864_2 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000004128 110.0
HFD2_k127_2134673_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1679.0
HFD2_k127_2134673_1 Carboxypeptidase regulatory-like domain - - - 3.266e-309 981.0
HFD2_k127_2134673_10 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 529.0
HFD2_k127_2134673_11 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 537.0
HFD2_k127_2134673_12 oxidation-reduction process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 519.0
HFD2_k127_2134673_13 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 503.0
HFD2_k127_2134673_14 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 490.0
HFD2_k127_2134673_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 500.0
HFD2_k127_2134673_16 phosphorelay sensor kinase activity K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000934 430.0
HFD2_k127_2134673_17 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 359.0
HFD2_k127_2134673_18 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 291.0
HFD2_k127_2134673_19 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 285.0
HFD2_k127_2134673_2 Oligopeptide transporter OPT - - - 4.193e-284 895.0
HFD2_k127_2134673_20 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004762 243.0
HFD2_k127_2134673_21 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000005204 234.0
HFD2_k127_2134673_22 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000102 220.0
HFD2_k127_2134673_23 FG-GAP repeat protein - - - 0.0000000000000000000000000000000000000000000000000188 204.0
HFD2_k127_2134673_24 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.00000000000000000000000000000000000000000000000004791 181.0
HFD2_k127_2134673_25 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000004522 173.0
HFD2_k127_2134673_26 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.0000000000000000000000000000000000000000000001833 171.0
HFD2_k127_2134673_27 Phosphoglycerate mutase family K08296 - - 0.000000000000000000000000000000000000000000004272 168.0
HFD2_k127_2134673_28 arylsulfatase activity K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000475 178.0
HFD2_k127_2134673_29 DNA-directed 5'-3' RNA polymerase activity K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000222 130.0
HFD2_k127_2134673_3 PFAM ABC transporter K11085 - - 1.498e-264 834.0
HFD2_k127_2134673_30 TIGRFAM TonB family protein K03832 - - 0.0000000000000000000006168 110.0
HFD2_k127_2134673_31 sequence-specific DNA binding K15539 - - 0.000000000000000001068 89.0
HFD2_k127_2134673_32 Methyltransferase - - - 0.0000184 48.0
HFD2_k127_2134673_33 determination of stomach left/right asymmetry K10407 - - 0.00002628 57.0
HFD2_k127_2134673_4 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 1.902e-247 773.0
HFD2_k127_2134673_5 Response regulator receiver - - - 1.393e-238 747.0
HFD2_k127_2134673_6 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 1.991e-236 742.0
HFD2_k127_2134673_7 Histidine kinase - - - 1.473e-203 641.0
HFD2_k127_2134673_8 aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008331 611.0
HFD2_k127_2134673_9 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 553.0
HFD2_k127_2152625_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1076.0
HFD2_k127_2152625_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000009861 90.0
HFD2_k127_2152625_2 methyltransferase - - - 0.000002408 53.0
HFD2_k127_2165478_0 Carboxypeptidase regulatory-like domain - - - 1.136e-321 1015.0
HFD2_k127_2165478_1 Carboxypeptidase regulatory-like domain - - - 2.342e-247 807.0
HFD2_k127_2165478_10 L-rhamnose-proton symport protein (RhaT) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 389.0
HFD2_k127_2165478_11 Glycosyl hydrolase family 20, domain 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 405.0
HFD2_k127_2165478_12 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 385.0
HFD2_k127_2165478_13 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 325.0
HFD2_k127_2165478_14 PFAM Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 317.0
HFD2_k127_2165478_15 3-hydroxyacyl-CoA dehydrogenase NAD-binding K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 300.0
HFD2_k127_2165478_16 Domain of unknown function (DUF4962) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001416 304.0
HFD2_k127_2165478_17 DNA-binding transcription factor activity K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000002649 240.0
HFD2_k127_2165478_18 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000001215 233.0
HFD2_k127_2165478_19 N-terminus of Esterase_SGNH_hydro-type - - - 0.0000000000000000000000000000000000000000000000000000000000000008423 235.0
HFD2_k127_2165478_2 Cys/Met metabolism PLP-dependent enzyme K01042 - 2.9.1.1 1.363e-225 711.0
HFD2_k127_2165478_20 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000002728 219.0
HFD2_k127_2165478_21 polygalacturonase activity - - - 0.00000000000000000000000000000000000000000000000000000001315 222.0
HFD2_k127_2165478_22 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000009317 174.0
HFD2_k127_2165478_23 PFAM Uncharacterised BCR, COG1649 K05988 - 3.2.1.11 0.0000000000000000000000000000000000000002951 168.0
HFD2_k127_2165478_24 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000003623 106.0
HFD2_k127_2165478_26 - - - - 0.00009998 48.0
HFD2_k127_2165478_3 - - - - 9.404e-209 672.0
HFD2_k127_2165478_4 Putative N-acetylmannosamine-6-phosphate epimerase K01788 - 5.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000726 547.0
HFD2_k127_2165478_6 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 518.0
HFD2_k127_2165478_7 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 507.0
HFD2_k127_2165478_8 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 434.0
HFD2_k127_2165478_9 PFAM ATP-binding region, ATPase domain protein domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 401.0
HFD2_k127_2209967_0 Transposase IS66 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 581.0
HFD2_k127_2209967_1 Domain of unknown function (DUF4338) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 438.0
HFD2_k127_2209967_2 IS66 Orf2 like protein K07484 - - 0.0000000000000000000000000000000000000000000005159 169.0
HFD2_k127_2209967_3 - - - - 0.00000000000000000000000002732 124.0
HFD2_k127_2209967_4 - - - - 0.000000001865 59.0
HFD2_k127_2218834_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 1.875e-216 691.0
HFD2_k127_2218834_1 PFAM Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 343.0
HFD2_k127_2218834_2 Cytochrome c K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009652 272.0
HFD2_k127_2218834_3 pfam nipsnap - - - 0.000000000000000000000000000000000000000000000000000000000000000000001011 241.0
HFD2_k127_2218834_4 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000003116 158.0
HFD2_k127_2218834_5 Cytochrome c K02720 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.00000000000000000000000007058 120.0
HFD2_k127_2218834_6 Cytochrome c K00413 - - 0.00002852 48.0
HFD2_k127_2233113_0 Alpha-L-arabinofuranosidase K01209 - 3.2.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000003605 283.0
HFD2_k127_2251573_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 4.518e-261 830.0
HFD2_k127_2251573_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001955 284.0
HFD2_k127_2269709_0 protocatechuate 3,4-dioxygenase activity - - - 0.0 1269.0
HFD2_k127_2269709_1 arylsulfatase activity K01133 - 3.1.6.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 618.0
HFD2_k127_2269709_2 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 538.0
HFD2_k127_2269709_3 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 376.0
HFD2_k127_2269709_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 379.0
HFD2_k127_2273690_0 transport - - - 0.0 1447.0
HFD2_k127_2273690_1 transport - - - 0.0 1337.0
HFD2_k127_2273690_10 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003376 280.0
HFD2_k127_2273690_11 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001633 251.0
HFD2_k127_2273690_12 Oxidoreductase molybdopterin binding domain K07147 - - 0.0000000000000000000000000000000000000000000000000000000000381 221.0
HFD2_k127_2273690_13 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000001701 201.0
HFD2_k127_2273690_14 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000008655 202.0
HFD2_k127_2273690_15 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000001932 160.0
HFD2_k127_2273690_16 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000032 135.0
HFD2_k127_2273690_17 - - - - 0.0000000000000000000000000002208 127.0
HFD2_k127_2273690_19 - - - - 0.0000004295 61.0
HFD2_k127_2273690_2 Carboxypeptidase regulatory-like domain - - - 2.823e-291 936.0
HFD2_k127_2273690_20 Tetratricopeptide TPR_2 repeat protein - - - 0.0000006164 61.0
HFD2_k127_2273690_3 L-seryl-tRNASec selenium transferase activity K01042 - 2.9.1.1 1.393e-195 619.0
HFD2_k127_2273690_4 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 616.0
HFD2_k127_2273690_5 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 614.0
HFD2_k127_2273690_6 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 444.0
HFD2_k127_2273690_7 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 394.0
HFD2_k127_2273690_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008192 326.0
HFD2_k127_2273690_9 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000102 301.0
HFD2_k127_2280893_0 Penicillin amidase K01434 - 3.5.1.11 3.734e-248 786.0
HFD2_k127_2280893_1 Ribonuclease, Rne Rng family K08301 - - 6.282e-197 616.0
HFD2_k127_2280893_10 Glycosyltransferase like family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005477 285.0
HFD2_k127_2280893_11 L-seryl-tRNASec selenium transferase activity K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001172 280.0
HFD2_k127_2280893_12 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000008932 225.0
HFD2_k127_2280893_14 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000001796 196.0
HFD2_k127_2280893_15 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.00000000000000000000000000000000000000000000513 166.0
HFD2_k127_2280893_16 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000004424 153.0
HFD2_k127_2280893_17 - - - - 0.000000000000000000000000000002555 124.0
HFD2_k127_2280893_18 membrane transporter protein K07090 - - 0.0000000000000000000000000109 113.0
HFD2_k127_2280893_19 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000003583 114.0
HFD2_k127_2280893_2 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 588.0
HFD2_k127_2280893_20 - - - - 0.000000000000000000007905 99.0
HFD2_k127_2280893_21 Cold shock - - - 0.0005096 49.0
HFD2_k127_2280893_3 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009945 465.0
HFD2_k127_2280893_4 Amidohydrolase K10220 - 4.2.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 401.0
HFD2_k127_2280893_5 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 387.0
HFD2_k127_2280893_6 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 371.0
HFD2_k127_2280893_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 310.0
HFD2_k127_2280893_8 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 302.0
HFD2_k127_2280893_9 outer membrane autotransporter barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 296.0
HFD2_k127_2288676_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1179.0
HFD2_k127_2288676_1 - - - - 0.0 1060.0
HFD2_k127_2288676_10 serine-type peptidase activity K06978,K21105 - 3.1.1.102 0.00000000000000000000000000000000000000000000000000002358 212.0
HFD2_k127_2288676_11 Sulfatase - - - 0.00000000000000000000000000000000000000000000000001525 196.0
HFD2_k127_2288676_12 Rdx family K07401 - - 0.00000000000000000000000000000000000000002807 154.0
HFD2_k127_2288676_13 Response regulator, receiver - - - 0.000000000000000000000000000000000001161 144.0
HFD2_k127_2288676_14 methyltransferase activity - - - 0.00000000000000000000000000000000000162 149.0
HFD2_k127_2288676_15 Histidine kinase - - - 0.0000000000000000000000000001616 122.0
HFD2_k127_2288676_16 Carboxypeptidase regulatory-like domain - - - 0.000000000004151 68.0
HFD2_k127_2288676_17 - - - - 0.00000000001283 68.0
HFD2_k127_2288676_18 CHAP domain - - - 0.0000000007245 68.0
HFD2_k127_2288676_19 Regulatory protein, FmdB family - - - 0.000000008624 66.0
HFD2_k127_2288676_2 FAD dependent oxidoreductase K15736 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 574.0
HFD2_k127_2288676_3 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008736 534.0
HFD2_k127_2288676_4 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009755 449.0
HFD2_k127_2288676_5 PFAM glucosamine galactosamine-6-phosphate isomerase K02564 - 3.5.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 286.0
HFD2_k127_2288676_6 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000081 278.0
HFD2_k127_2288676_7 uridine phosphorylase activity K00757 - 2.4.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001012 277.0
HFD2_k127_2288676_8 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000001904 223.0
HFD2_k127_2288676_9 protocatechuate 3,4-dioxygenase activity K02014 - - 0.00000000000000000000000000000000000000000000000000000006519 220.0
HFD2_k127_2336907_0 Inner membrane component of T3SS, cytoplasmic domain - - - 3.216e-227 715.0
HFD2_k127_2336907_1 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 507.0
HFD2_k127_2336907_2 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 445.0
HFD2_k127_2336907_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008125 386.0
HFD2_k127_2336907_4 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 311.0
HFD2_k127_2336907_5 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000004295 203.0
HFD2_k127_2336907_6 gal1,galk K18674 GO:0003674,GO:0003824,GO:0004335,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019318,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.157 0.00002003 57.0
HFD2_k127_2469827_0 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 8.364e-298 951.0
HFD2_k127_2469827_1 amidase activity K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007705 578.0
HFD2_k127_2469827_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 467.0
HFD2_k127_2469827_3 Aminotransferase class-III K00822,K00833 - 2.6.1.18,2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 438.0
HFD2_k127_2469827_4 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 362.0
HFD2_k127_2469827_5 ribonuclease BN K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 325.0
HFD2_k127_2469827_6 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 350.0
HFD2_k127_2469827_7 SIR2-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 312.0
HFD2_k127_2469827_8 WD40 repeats - - - 0.000000000000000000000000000000000000000000000000000000000001675 228.0
HFD2_k127_2484132_0 AcrB/AcrD/AcrF family - - - 0.0 1143.0
HFD2_k127_2484132_1 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 415.0
HFD2_k127_2484132_2 protocatechuate 3,4-dioxygenase activity - - - 0.0000000000000005081 83.0
HFD2_k127_2484132_3 ASPIC and UnbV - - - 0.000000000000008515 75.0
HFD2_k127_2484132_4 PFAM TonB-dependent Receptor Plug - - - 0.00006586 51.0
HFD2_k127_2484132_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000817 47.0
HFD2_k127_2512527_0 acyl-CoA dehydrogenase activity K00249 - 1.3.8.7 0.0 1179.0
HFD2_k127_2512527_1 Belongs to the peptidase S8 family K20755 - 3.4.21.121 1.301e-302 953.0
HFD2_k127_2512527_10 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 438.0
HFD2_k127_2512527_11 PFAM Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 415.0
HFD2_k127_2512527_12 electron transfer activity K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007187 402.0
HFD2_k127_2512527_13 Glycosyl hydrolase family 20, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 382.0
HFD2_k127_2512527_14 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 375.0
HFD2_k127_2512527_15 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 354.0
HFD2_k127_2512527_16 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 360.0
HFD2_k127_2512527_17 TIR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 307.0
HFD2_k127_2512527_18 MoaE protein K21142 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000977 305.0
HFD2_k127_2512527_19 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008375 266.0
HFD2_k127_2512527_2 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 6.047e-286 893.0
HFD2_k127_2512527_20 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.0000000000000000000000000000000000000000000000000000003006 211.0
HFD2_k127_2512527_21 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000007713 192.0
HFD2_k127_2512527_22 catechol 1,2-dioxygenase - - - 0.0000000000000000000000000000000000003334 150.0
HFD2_k127_2512527_23 FMN reductase (NADPH) activity - - - 0.0000000000000000000000000000001246 144.0
HFD2_k127_2512527_24 - - - - 0.00000000000000000000000000001412 124.0
HFD2_k127_2512527_26 TonB-dependent receptor - - - 0.00000000000000000000000003414 123.0
HFD2_k127_2512527_27 - - - - 0.00000000000000000000000003757 109.0
HFD2_k127_2512527_28 - - - - 0.00000000000000000000006325 110.0
HFD2_k127_2512527_29 - - - - 0.0000000000000000000003102 104.0
HFD2_k127_2512527_3 TonB-dependent receptor - - - 1.141e-263 850.0
HFD2_k127_2512527_30 peptidase - - - 0.00000000000000000001704 96.0
HFD2_k127_2512527_31 Hfq protein K03666 - - 0.0000000000000000000174 93.0
HFD2_k127_2512527_32 Transcriptional regulatory protein, C terminal - - - 0.00006766 51.0
HFD2_k127_2512527_33 cAMP biosynthetic process K12132 - 2.7.11.1 0.0003443 44.0
HFD2_k127_2512527_4 Belongs to the malate synthase family K01638 - 2.3.3.9 3.37e-252 788.0
HFD2_k127_2512527_5 Domain of unknown function (DUF3459) K00700,K01236 - 2.4.1.18,3.2.1.141 6.778e-213 696.0
HFD2_k127_2512527_6 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 611.0
HFD2_k127_2512527_7 ATPase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 540.0
HFD2_k127_2512527_8 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 493.0
HFD2_k127_2512527_9 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 453.0
HFD2_k127_2516088_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005239 485.0
HFD2_k127_2516088_1 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 289.0
HFD2_k127_2516088_2 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000001165 244.0
HFD2_k127_2526543_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 2.777e-210 656.0
HFD2_k127_2526543_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009913 560.0
HFD2_k127_2526543_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 339.0
HFD2_k127_2526543_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000001831 109.0
HFD2_k127_2526543_4 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.00000000000001149 73.0
HFD2_k127_2538364_0 Carboxypeptidase regulatory-like domain - - - 0.0 1093.0
HFD2_k127_2538364_1 TIGRFAM malto-oligosyltrehalose trehalohydrolase K00700 - 2.4.1.18 0.0 1071.0
HFD2_k127_2538364_10 PFAM aminotransferase class V K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000001322 166.0
HFD2_k127_2538364_11 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000008932 146.0
HFD2_k127_2538364_14 - - - - 0.00001119 52.0
HFD2_k127_2538364_2 PFAM oxidoreductase domain protein - - - 2.562e-236 740.0
HFD2_k127_2538364_3 DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 3.782e-233 730.0
HFD2_k127_2538364_4 His Kinase A (phosphoacceptor) domain - - - 2.103e-213 679.0
HFD2_k127_2538364_5 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 561.0
HFD2_k127_2538364_6 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 413.0
HFD2_k127_2538364_7 Kdo2-lipid A biosynthetic process K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 402.0
HFD2_k127_2538364_8 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 396.0
HFD2_k127_2538364_9 PFAM Adenosine AMP deaminase K01488,K18286 - 3.5.4.4,3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009765 349.0
HFD2_k127_2564310_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1983.0
HFD2_k127_2564310_1 Aldehyde dehydrogenase family K00128 - 1.2.1.3 3.02e-265 825.0
HFD2_k127_2564310_10 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K19715 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0043170,GO:0044238,GO:0071704,GO:1901576 2.6.1.109 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 312.0
HFD2_k127_2564310_11 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 305.0
HFD2_k127_2564310_12 D-mannonate dehydratase (UxuA) K01686 - 4.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005852 287.0
HFD2_k127_2564310_13 acid phosphatase activity K03651 - 3.1.4.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000006035 267.0
HFD2_k127_2564310_14 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007116 255.0
HFD2_k127_2564310_15 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000002409 238.0
HFD2_k127_2564310_16 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000000000001145 221.0
HFD2_k127_2564310_17 COG0657 Esterase lipase - - - 0.00000000000000000000000000000000000000000000000001833 190.0
HFD2_k127_2564310_18 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000001221 146.0
HFD2_k127_2564310_19 SnoaL-like domain - - - 0.00000000000000000000000000000000003768 144.0
HFD2_k127_2564310_2 von Willebrand factor (vWF) type A domain K07114 - - 9.984e-199 621.0
HFD2_k127_2564310_20 - - - - 0.0000000000000000000000000001029 119.0
HFD2_k127_2564310_3 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 597.0
HFD2_k127_2564310_4 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 617.0
HFD2_k127_2564310_5 Bacterial type II and III secretion system protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 553.0
HFD2_k127_2564310_6 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 522.0
HFD2_k127_2564310_7 Concanavalin A-like lectin/glucanases superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007143 473.0
HFD2_k127_2564310_8 transmembrane transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006894 377.0
HFD2_k127_2569494_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 548.0
HFD2_k127_2569494_1 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 352.0
HFD2_k127_2574985_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1097.0
HFD2_k127_2574985_1 Domain of unknown function (DUF4139) - - - 3.877e-238 753.0
HFD2_k127_2574985_10 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 391.0
HFD2_k127_2574985_11 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 385.0
HFD2_k127_2574985_12 PFAM Class II aldolase K03077 - 5.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005762 350.0
HFD2_k127_2574985_13 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 352.0
HFD2_k127_2574985_14 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 353.0
HFD2_k127_2574985_15 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 334.0
HFD2_k127_2574985_16 and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006859 345.0
HFD2_k127_2574985_17 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 306.0
HFD2_k127_2574985_18 ethanolamine kinase activity K04343,K07251,K18844 - 2.7.1.72,2.7.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 300.0
HFD2_k127_2574985_19 Diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007177 274.0
HFD2_k127_2574985_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 563.0
HFD2_k127_2574985_20 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001843 263.0
HFD2_k127_2574985_21 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006783 238.0
HFD2_k127_2574985_22 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000009528 247.0
HFD2_k127_2574985_23 efflux transmembrane transporter activity K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000001345 242.0
HFD2_k127_2574985_24 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000000000007621 157.0
HFD2_k127_2574985_25 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000002047 136.0
HFD2_k127_2574985_26 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000002458 139.0
HFD2_k127_2574985_28 methyltransferase - - - 0.00000000000000000000000000000783 128.0
HFD2_k127_2574985_29 PFAM type IV pilus assembly PilZ - - - 0.000000000002787 71.0
HFD2_k127_2574985_3 COG1073 Hydrolases of the alpha beta superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 565.0
HFD2_k127_2574985_30 NAD(FAD)-dependent dehydrogenases - - - 0.000000457 55.0
HFD2_k127_2574985_4 arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 541.0
HFD2_k127_2574985_5 PFAM penicillin-binding protein transpeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 503.0
HFD2_k127_2574985_6 PFAM sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 466.0
HFD2_k127_2574985_7 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 456.0
HFD2_k127_2574985_8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 448.0
HFD2_k127_2574985_9 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 424.0
HFD2_k127_257847_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K00179,K04090 - 1.2.7.8 6.576e-294 938.0
HFD2_k127_257847_1 PFAM Mandelate racemase muconate lactonizing enzyme, N-terminal domain protein K01684 - 4.2.1.6 2.823e-219 685.0
HFD2_k127_257847_10 - - - - 0.0000000000000000000000000000000000000000000000000000000275 210.0
HFD2_k127_257847_11 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000255 132.0
HFD2_k127_257847_12 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000002108 123.0
HFD2_k127_257847_13 Trm112p-like protein K09791 - - 0.000000000000000000000000000114 115.0
HFD2_k127_257847_2 PFAM carbohydrate kinase K00848 - 2.7.1.5 4.057e-204 655.0
HFD2_k127_257847_3 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009568 623.0
HFD2_k127_257847_4 Uncharacterised protein family (UPF0261) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 462.0
HFD2_k127_257847_5 Phosphoenolpyruvate hydrolase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 392.0
HFD2_k127_257847_6 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007552 352.0
HFD2_k127_257847_7 alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000001605 243.0
HFD2_k127_257847_8 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.0000000000000000000000000000000000000000000000000000000006451 204.0
HFD2_k127_257847_9 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000001293 211.0
HFD2_k127_2611381_0 Cytochrome c - - - 0.0 1288.0
HFD2_k127_2611381_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 7.479e-312 960.0
HFD2_k127_2611381_10 Major Facilitator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 433.0
HFD2_k127_2611381_11 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 421.0
HFD2_k127_2611381_12 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 400.0
HFD2_k127_2611381_13 PFAM DAHP synthetase I K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 381.0
HFD2_k127_2611381_14 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 367.0
HFD2_k127_2611381_15 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 353.0
HFD2_k127_2611381_16 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 353.0
HFD2_k127_2611381_17 metallophosphoesterase K07096,K07496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009526 293.0
HFD2_k127_2611381_18 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 291.0
HFD2_k127_2611381_19 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006864 265.0
HFD2_k127_2611381_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 1.508e-227 714.0
HFD2_k127_2611381_20 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004684 263.0
HFD2_k127_2611381_21 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002148 249.0
HFD2_k127_2611381_22 Pfam:N_methyl_2 - - - 0.000000000000000000000000000000000000000000000000000000000000000006962 228.0
HFD2_k127_2611381_23 Putative zinc-finger - - - 0.0000000000000000000000000000000000000000000000000000000996 208.0
HFD2_k127_2611381_24 Histone-lysine N-methyltransferase K09186,K14959 GO:0000976,GO:0000977,GO:0000980,GO:0000981,GO:0001012,GO:0001067,GO:0001158,GO:0001894,GO:0002376,GO:0002520,GO:0002682,GO:0003002,GO:0003008,GO:0003674,GO:0003676,GO:0003677,GO:0003680,GO:0003682,GO:0003690,GO:0003700,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006325,GO:0006351,GO:0006355,GO:0006357,GO:0006366,GO:0006464,GO:0006473,GO:0006475,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0007275,GO:0007389,GO:0007610,GO:0007611,GO:0007612,GO:0007623,GO:0007632,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008270,GO:0008276,GO:0008285,GO:0008306,GO:0008542,GO:0008757,GO:0009058,GO:0009059,GO:0009314,GO:0009416,GO:0009628,GO:0009790,GO:0009791,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009952,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010646,GO:0016043,GO:0016070,GO:0016278,GO:0016279,GO:0016569,GO:0016570,GO:0016571,GO:0016573,GO:0016740,GO:0016741,GO:0018022,GO:0018023,GO:0018024,GO:0018026,GO:0018027,GO:0018130,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0022607,GO:0023051,GO:0030097,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031399,GO:0031401,GO:0031974,GO:0031981,GO:0032259,GO:0032268,GO:0032270,GO:0032409,GO:0032411,GO:0032501,GO:0032502,GO:0032774,GO:0032879,GO:0032922,GO:0032991,GO:0033043,GO:0033044,GO:0034641,GO:0034645,GO:0034654,GO:0034708,GO:0034968,GO:0035065,GO:0035097,GO:0035162,GO:0035326,GO:0035640,GO:0036211,GO:0042054,GO:0042127,GO:0042393,GO:0042592,GO:0042800,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043414,GO:0043543,GO:0043565,GO:0043933,GO:0043967,GO:0043984,GO:0044030,GO:0044085,GO:0044093,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0044648,GO:0044665,GO:0044728,GO:0045322,GO:0045595,GO:0045637,GO:0045652,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0046483,GO:0046872,GO:0046914,GO:0046983,GO:0048167,GO:0048168,GO:0048172,GO:0048511,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048536,GO:0048568,GO:0048583,GO:0048584,GO:0048731,GO:0048856,GO:0048871,GO:0048872,GO:0048873,GO:0050789,GO:0050793,GO:0050794,GO:0050804,GO:0050877,GO:0050890,GO:0050896,GO:0051049,GO:0051050,GO:0051052,GO:0051053,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051239,GO:0051246,GO:0051247,GO:0051252,GO:0051254,GO:0051276,GO:0051568,GO:0051569,GO:0051571,GO:0060216,GO:0060249,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070577,GO:0071339,GO:0071440,GO:0071704,GO:0071840,GO:0080090,GO:0080182,GO:0090304,GO:0097159,GO:0097659,GO:0099177,GO:0140030,GO:0140033,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901532,GO:1901564,GO:1901576,GO:1901674,GO:1901983,GO:1902036,GO:1902275,GO:1902494,GO:1902680,GO:1903506,GO:1903508,GO:1903706,GO:1905269,GO:1905642,GO:1990234,GO:1990837,GO:2000026,GO:2000112,GO:2000615,GO:2000736,GO:2000756,GO:2001023,GO:2001025,GO:2001038,GO:2001040,GO:2001141,GO:2001252 2.1.1.43 0.00000000000000000000009552 112.0
HFD2_k127_2611381_25 - - - - 0.00000000000000000004952 98.0
HFD2_k127_2611381_3 Protein of unknown function (DUF1501) - - - 6.144e-226 707.0
HFD2_k127_2611381_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 601.0
HFD2_k127_2611381_5 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 545.0
HFD2_k127_2611381_6 Putative adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 543.0
HFD2_k127_2611381_7 unsaturated chondroitin disaccharide hydrolase activity K18581 - 3.2.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 515.0
HFD2_k127_2611381_8 C-terminal, D2-small domain, of ClpB protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 480.0
HFD2_k127_2611381_9 PFAM von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 482.0
HFD2_k127_2618744_0 - - - - 4.433e-319 987.0
HFD2_k127_2618744_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.45e-304 945.0
HFD2_k127_2618744_10 DinB family - - - 0.000000000000000000000000000000000000000000000002087 185.0
HFD2_k127_2618744_11 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000002176 168.0
HFD2_k127_2618744_13 ASPIC and UnbV - - - 0.000000000000000000000000000000000000006344 153.0
HFD2_k127_2618744_14 peptidyl-tyrosine sulfation - - - 0.00000000373 68.0
HFD2_k127_2618744_2 PFAM natural resistance-associated macrophage protein K03322 - - 5.513e-286 890.0
HFD2_k127_2618744_3 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 602.0
HFD2_k127_2618744_4 protein import - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006363 587.0
HFD2_k127_2618744_5 peptidase dimerisation domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 537.0
HFD2_k127_2618744_6 Protein of unknown function (DUF2961) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 516.0
HFD2_k127_2618744_7 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 428.0
HFD2_k127_2618744_8 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 347.0
HFD2_k127_2618744_9 Diacylglycerol kinase catalytic domain (presumed) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003471 286.0
HFD2_k127_2645457_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 1.783e-283 884.0
HFD2_k127_2645457_1 MacB-like periplasmic core domain - - - 1.507e-262 827.0
HFD2_k127_2645457_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 4.606e-262 822.0
HFD2_k127_2645457_3 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 589.0
HFD2_k127_2645457_4 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 359.0
HFD2_k127_2645457_5 acetylesterase activity - - - 0.0000000000000000000000000000000000000000000000000191 194.0
HFD2_k127_2645457_6 methylamine metabolic process K15977 - - 0.000000000000000000000000000000002672 132.0
HFD2_k127_2645457_7 - - - - 0.0000000000000000557 89.0
HFD2_k127_2645457_8 - - - - 0.00000000929 68.0
HFD2_k127_2660367_0 Protein of unknown function (DUF1553) - - - 0.0 1146.0
HFD2_k127_2660367_1 ATPase involved in DNA repair K13924 - 2.1.1.80,3.1.1.61 6.656e-289 927.0
HFD2_k127_2660367_10 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008926 436.0
HFD2_k127_2660367_11 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 432.0
HFD2_k127_2660367_12 Acyl-CoA dehydrogenase, C-terminal domain K16047 - 1.14.14.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 387.0
HFD2_k127_2660367_13 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 361.0
HFD2_k127_2660367_14 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 335.0
HFD2_k127_2660367_15 AntiSigma factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 290.0
HFD2_k127_2660367_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005806 273.0
HFD2_k127_2660367_17 ribosome binding - - - 0.00000000000000000000002607 101.0
HFD2_k127_2660367_18 Transposase and inactivated derivatives - - - 0.00000003199 62.0
HFD2_k127_2660367_19 SPTR PIN domain protein like protein - - - 0.000007308 50.0
HFD2_k127_2660367_2 Wd-40 repeat - - - 5.126e-276 870.0
HFD2_k127_2660367_3 Protein of unknown function (DUF1501) - - - 1.028e-260 808.0
HFD2_k127_2660367_4 cell wall glycoprotein biosynthetic process - - - 3.373e-220 687.0
HFD2_k127_2660367_5 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 4.186e-197 646.0
HFD2_k127_2660367_6 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009754 612.0
HFD2_k127_2660367_7 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006846 536.0
HFD2_k127_2660367_8 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 517.0
HFD2_k127_2660367_9 WD domain, G-beta repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008522 448.0
HFD2_k127_2708538_0 domain protein - - - 0.0 1153.0
HFD2_k127_2708538_1 BNR repeat-like domain K05989 - 3.2.1.40 7.19e-207 676.0
HFD2_k127_2708538_2 PFAM oxidoreductase domain protein - - - 1.17e-198 627.0
HFD2_k127_2708538_3 PFAM Amidohydrolase 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008123 541.0
HFD2_k127_2708538_4 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 446.0
HFD2_k127_2708538_5 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 368.0
HFD2_k127_2708538_6 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000000000000000001085 186.0
HFD2_k127_2708538_7 domain protein K14475 - - 0.000000000000000000000000000000262 144.0
HFD2_k127_2708538_8 PFAM response regulator receiver K02483,K07658 - - 0.0003267 46.0
HFD2_k127_2720857_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1337.0
HFD2_k127_2720857_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 1.574e-235 732.0
HFD2_k127_2720857_10 protein histidine kinase activity - - - 0.00000000001139 77.0
HFD2_k127_2720857_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 9.593e-207 653.0
HFD2_k127_2720857_3 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 516.0
HFD2_k127_2720857_4 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 486.0
HFD2_k127_2720857_5 Pfam:Methyltransf_6 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 347.0
HFD2_k127_2720857_6 response regulator K02282 - - 0.000000000000000000000000000000000000000000000000000000386 208.0
HFD2_k127_2720857_7 Histidine kinase K07683 - 2.7.13.3 0.00000000000000000000000000000000000000000000000004424 196.0
HFD2_k127_2720857_8 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.000000000000000000000000000000000003345 139.0
HFD2_k127_2720857_9 - - - - 0.000000000000000003056 86.0
HFD2_k127_2755915_0 extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 488.0
HFD2_k127_2755915_1 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 400.0
HFD2_k127_2755915_2 WD40-like Beta Propeller Repeat K01730 - 4.2.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 387.0
HFD2_k127_2755915_3 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000005961 218.0
HFD2_k127_2755915_4 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000337 188.0
HFD2_k127_2755915_5 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000008977 113.0
HFD2_k127_2755915_6 HD domain - - - 0.0000001733 57.0
HFD2_k127_2761238_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008666 552.0
HFD2_k127_2761238_1 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004785 347.0
HFD2_k127_2761238_2 N-acetylglucosaminylinositol deacetylase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 315.0
HFD2_k127_2761238_3 carboxylic acid catabolic process K01706 - 4.2.1.40 0.00000000000000000000000000000000000000000000000000002429 202.0
HFD2_k127_2761238_4 carboxylic acid catabolic process K01684 - 4.2.1.6 0.000000000000000000000000000114 130.0
HFD2_k127_2763029_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1571.0
HFD2_k127_2763029_1 transport - - - 0.0 1065.0
HFD2_k127_2763029_10 BNR repeat-like domain K05989 - 3.2.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006681 541.0
HFD2_k127_2763029_11 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K08323 - 4.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 508.0
HFD2_k127_2763029_12 Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 479.0
HFD2_k127_2763029_13 PFAM von Willebrand factor type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 465.0
HFD2_k127_2763029_14 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 451.0
HFD2_k127_2763029_15 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 420.0
HFD2_k127_2763029_16 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 414.0
HFD2_k127_2763029_17 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 404.0
HFD2_k127_2763029_18 ADP-ribosylglycohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 408.0
HFD2_k127_2763029_19 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 392.0
HFD2_k127_2763029_2 HELICc2 K03722 - 3.6.4.12 9.02e-319 1003.0
HFD2_k127_2763029_20 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 402.0
HFD2_k127_2763029_21 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 366.0
HFD2_k127_2763029_22 PFAM Semialdehyde dehydrogenase K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 353.0
HFD2_k127_2763029_23 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 349.0
HFD2_k127_2763029_24 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 312.0
HFD2_k127_2763029_25 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 293.0
HFD2_k127_2763029_26 NnrS protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008948 290.0
HFD2_k127_2763029_27 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003354 248.0
HFD2_k127_2763029_29 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000569 222.0
HFD2_k127_2763029_3 Beta-eliminating lyase K01667 - 4.1.99.1 1.388e-244 761.0
HFD2_k127_2763029_30 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000007332 222.0
HFD2_k127_2763029_31 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599,K14080 - 2.1.1.246,4.1.1.37 0.00000000000000000000000000000000000000000000000000000003752 209.0
HFD2_k127_2763029_32 Lipopolysaccharide-assembly - - - 0.0000000000000000000000000000000000000000000000000002461 198.0
HFD2_k127_2763029_33 4Fe-4S dicluster domain K05524 - - 0.0000000000000000000000000000000000000000000000000105 181.0
HFD2_k127_2763029_34 - - - - 0.0000000000000000000000000000000000000006312 149.0
HFD2_k127_2763029_35 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000000000000001459 131.0
HFD2_k127_2763029_36 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000008251 115.0
HFD2_k127_2763029_37 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000804 117.0
HFD2_k127_2763029_38 Vitamin B12 dependent methionine synthase, activation domain - - - 0.0000000000000005509 88.0
HFD2_k127_2763029_39 transporter antisigma-factor antagonist STAS K04749 - - 0.0000000002738 68.0
HFD2_k127_2763029_4 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 3.064e-223 698.0
HFD2_k127_2763029_40 protein carbamoylation K04656,K05927 - 1.12.5.1 0.0000000003883 64.0
HFD2_k127_2763029_41 peptidyl-tyrosine sulfation - - - 0.0000001734 63.0
HFD2_k127_2763029_5 ABC transporter K10441,K10545,K10562 - 3.6.3.17 9.826e-198 627.0
HFD2_k127_2763029_6 peptidyl-tyrosine sulfation - - - 2.185e-196 635.0
HFD2_k127_2763029_7 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 603.0
HFD2_k127_2763029_8 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 524.0
HFD2_k127_2763029_9 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 521.0
HFD2_k127_2764567_0 Heat shock 70 kDa protein K04043 - - 0.0 1063.0
HFD2_k127_2764567_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 592.0
HFD2_k127_2764567_2 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002356 281.0
HFD2_k127_2764567_3 Oxidoreductase FAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001401 258.0
HFD2_k127_2764567_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001665 234.0
HFD2_k127_2764567_5 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000001132 214.0
HFD2_k127_2764567_6 PFAM regulatory protein, MerR K13640 - - 0.000000000000000000000000000000000000000000000000000001049 195.0
HFD2_k127_2764567_7 ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000006271 198.0
HFD2_k127_2764567_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000004303 184.0
HFD2_k127_2764567_9 sirohydrochlorin cobaltochelatase activity K03795 - 4.99.1.3 0.000000000000000000000001799 108.0
HFD2_k127_2771277_0 Radical SAM superfamily K06937 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 357.0
HFD2_k127_2771277_1 PFAM amino acid permease-associated region K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 365.0
HFD2_k127_2771277_2 lipoprotein biosynthetic process K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001538 284.0
HFD2_k127_2771277_3 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000001723 138.0
HFD2_k127_2771277_4 Methyltransferase domain - - - 0.0000000000000000000000000001207 127.0
HFD2_k127_2791238_0 signal transduction histidine kinase - - - 6.625e-254 800.0
HFD2_k127_2791238_1 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 1.683e-240 767.0
HFD2_k127_2791238_10 Pfam:DUF310 - - - 0.0000000000000000000000000000000000000000000000000000000000000000008833 231.0
HFD2_k127_2791238_11 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000000000000000000000000000000002642 244.0
HFD2_k127_2791238_12 Response regulator receiver - - - 0.0000000000000000000000001107 111.0
HFD2_k127_2791238_13 crispr-associated protein K07016 - - 0.0000000000000000000009956 94.0
HFD2_k127_2791238_14 Carboxypeptidase regulatory-like domain - - - 0.0000004033 59.0
HFD2_k127_2791238_2 Carboxypeptidase regulatory-like domain - - - 1.575e-199 657.0
HFD2_k127_2791238_3 RAMP superfamily K19140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 569.0
HFD2_k127_2791238_4 methyltransferase activity K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 545.0
HFD2_k127_2791238_5 RAMP superfamily K09002 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 469.0
HFD2_k127_2791238_7 CRISPR-associated RAMP protein, Csm4 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 429.0
HFD2_k127_2791238_8 teichoic acid transport K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 414.0
HFD2_k127_2791238_9 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 309.0
HFD2_k127_2792210_0 transport - - - 0.0 1112.0
HFD2_k127_2792210_1 amine dehydrogenase activity K14647,K21449 - - 1.656e-247 797.0
HFD2_k127_2792210_10 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009541 309.0
HFD2_k127_2792210_11 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000001392 206.0
HFD2_k127_2792210_12 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000008475 210.0
HFD2_k127_2792210_13 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000001192 201.0
HFD2_k127_2792210_14 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000001672 166.0
HFD2_k127_2792210_15 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000002462 156.0
HFD2_k127_2792210_16 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.00000000000000000000000000000000000001968 147.0
HFD2_k127_2792210_2 Alpha-L-arabinofuranosidase C-terminal domain K01209 - 3.2.1.55 2.435e-235 745.0
HFD2_k127_2792210_3 amino acid K03294 - - 3.518e-220 691.0
HFD2_k127_2792210_4 amino acid K03294 - - 1.393e-199 633.0
HFD2_k127_2792210_5 amino acid K03294,K19540 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 624.0
HFD2_k127_2792210_6 N-Acyl-D-aspartate D-glutamate deacylase K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 541.0
HFD2_k127_2792210_7 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 407.0
HFD2_k127_2792210_8 COGs COG0673 dehydrogenase and related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000556 392.0
HFD2_k127_2792210_9 N-acetylglucosaminylinositol deacetylase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 349.0
HFD2_k127_2839990_0 MacB-like periplasmic core domain K02004 - - 0.0 1038.0
HFD2_k127_2839990_1 SMART Elongator protein 3 MiaB NifB - - - 1.327e-277 859.0
HFD2_k127_2839990_10 - - - - 0.00000000000000000000000000000000000000000000262 167.0
HFD2_k127_2839990_11 Protein of unknown function (DUF1552) - - - 0.000000000000000000003702 93.0
HFD2_k127_2839990_12 manually curated - - - 0.0000000000000000006702 92.0
HFD2_k127_2839990_14 lyase activity - - - 0.00000000002971 74.0
HFD2_k127_2839990_16 - - - - 0.000722 51.0
HFD2_k127_2839990_2 MacB-like periplasmic core domain - - - 1.768e-194 643.0
HFD2_k127_2839990_3 response to abiotic stimulus K06867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 600.0
HFD2_k127_2839990_4 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 415.0
HFD2_k127_2839990_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 332.0
HFD2_k127_2839990_6 Protein of unknown function (DUF1445) - - - 0.00000000000000000000000000000000000000000000000000000000000004356 220.0
HFD2_k127_2839990_7 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000001122 217.0
HFD2_k127_2839990_8 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000000000368 211.0
HFD2_k127_2839990_9 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000000002251 172.0
HFD2_k127_2843770_0 Cytochrome c - - - 4.196e-277 880.0
HFD2_k127_2843770_1 Protein of unknown function (DUF1501) - - - 1.032e-219 690.0
HFD2_k127_2843770_10 Cold shock protein domain K03704 - - 0.0000000000000000000000000000000002674 134.0
HFD2_k127_2843770_11 polysaccharide deacetylase - - - 0.0000000000000000000000000000002052 126.0
HFD2_k127_2843770_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 606.0
HFD2_k127_2843770_3 C-terminal, D2-small domain, of ClpB protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 473.0
HFD2_k127_2843770_4 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 316.0
HFD2_k127_2843770_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 294.0
HFD2_k127_2843770_6 Pfam:DUF2276 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001502 270.0
HFD2_k127_2843770_7 ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component - - - 0.0000000000000000000000000000000000000000000000000000000000001566 218.0
HFD2_k127_2843770_8 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000003561 157.0
HFD2_k127_2843770_9 Translation initiation factor 1A / IF-1 K02518 - - 0.00000000000000000000000000000000000005834 143.0
HFD2_k127_2845194_0 Putative phage tail protein - - - 0.0 1500.0
HFD2_k127_2845194_1 MacB-like periplasmic core domain - - - 0.0 1118.0
HFD2_k127_2845194_10 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 311.0
HFD2_k127_2845194_11 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000001332 207.0
HFD2_k127_2845194_12 PFAM transcriptional regulator PadR family protein - - - 0.000000000000000000000000000000000000000000000001844 176.0
HFD2_k127_2845194_13 amine dehydrogenase activity K12287 - - 0.000000000000000000000000000000000004397 149.0
HFD2_k127_2845194_14 Conserved hypothetical protein 2217 (DUF2460) - - - 0.000000000000000000000000008912 113.0
HFD2_k127_2845194_15 Belongs to the UPF0235 family K09131 - - 0.00000000000000000000000001513 111.0
HFD2_k127_2845194_16 - - - - 0.000000000000001126 86.0
HFD2_k127_2845194_18 protocatechuate 3,4-dioxygenase activity K02014 - - 0.0000001824 58.0
HFD2_k127_2845194_19 Carboxypeptidase regulatory-like domain - - - 0.0002187 46.0
HFD2_k127_2845194_2 tail sheath protein - - - 0.0 1109.0
HFD2_k127_2845194_20 amine dehydrogenase activity K12287 - - 0.0002373 50.0
HFD2_k127_2845194_21 - - - - 0.0007745 42.0
HFD2_k127_2845194_3 amino acid activation for nonribosomal peptide biosynthetic process - - - 9.688e-195 620.0
HFD2_k127_2845194_4 symporter activity K03307,K11928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 604.0
HFD2_k127_2845194_5 Wzt C-terminal domain K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 599.0
HFD2_k127_2845194_6 PFAM peptidase M24 K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 564.0
HFD2_k127_2845194_7 WD40 domain protein beta Propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 460.0
HFD2_k127_2845194_8 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 446.0
HFD2_k127_2845194_9 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009433 430.0
HFD2_k127_2858290_0 Peptidase M1, membrane alanine aminopeptidase - - - 5e-324 1001.0
HFD2_k127_2858290_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 3.611e-264 819.0
HFD2_k127_2858290_10 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00058 - 1.1.1.26,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 339.0
HFD2_k127_2858290_11 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 293.0
HFD2_k127_2858290_12 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 291.0
HFD2_k127_2858290_13 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000000000000000005439 228.0
HFD2_k127_2858290_14 2-epimerase K16213 - 5.1.3.11 0.00000000000000000000000000000000000000000000000000004722 202.0
HFD2_k127_2858290_15 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000003177 169.0
HFD2_k127_2858290_16 - - - - 0.00000000000000000000000000000000000000148 158.0
HFD2_k127_2858290_2 Beta-eliminating lyase K01668 - 4.1.99.2 5.545e-224 701.0
HFD2_k127_2858290_3 Zinc carboxypeptidase - - - 1e-210 683.0
HFD2_k127_2858290_4 Acyl-coa dehydrogenase K00249 - 1.3.8.7 2.402e-207 652.0
HFD2_k127_2858290_5 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 517.0
HFD2_k127_2858290_6 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 471.0
HFD2_k127_2858290_7 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 406.0
HFD2_k127_2858290_8 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 406.0
HFD2_k127_2858290_9 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 342.0
HFD2_k127_2881206_0 Carboxypeptidase regulatory-like domain - - - 2.42e-259 844.0
HFD2_k127_2881206_1 TonB-dependent receptor - - - 2.032e-243 769.0
HFD2_k127_2881206_10 PFAM Uncharacterised BCR, COG1649 - - - 0.0002057 53.0
HFD2_k127_2881206_11 SIR2-like domain - - - 0.0009014 46.0
HFD2_k127_2881206_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 1.163e-227 730.0
HFD2_k127_2881206_3 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 590.0
HFD2_k127_2881206_4 peptidase dimerisation domain K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005743 519.0
HFD2_k127_2881206_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 469.0
HFD2_k127_2881206_6 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 448.0
HFD2_k127_2881206_7 Belongs to the DapB family K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 376.0
HFD2_k127_2881206_8 Bacterial regulatory protein, Fis family K07712 - - 0.0000000005971 63.0
HFD2_k127_2881206_9 negative regulation of transcription, DNA-templated - - - 0.000000009502 60.0
HFD2_k127_288786_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1144.0
HFD2_k127_288786_1 Cytochrome c, class I - - - 8.653e-271 854.0
HFD2_k127_288786_10 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000928 328.0
HFD2_k127_288786_12 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 306.0
HFD2_k127_288786_13 TIGRFAM RNA polymerase sigma factor, FliA WhiG family K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000186 232.0
HFD2_k127_288786_14 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000000000000000000000000000005642 226.0
HFD2_k127_288786_16 - - - - 0.00000000000000000000000000000000000000001151 160.0
HFD2_k127_288786_17 Uncharacterized ACR, COG1678 - - - 0.0000000000000000000000000000000000005277 160.0
HFD2_k127_288786_18 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000000000000000001012 148.0
HFD2_k127_288786_2 Protein of unknown function (DUF1501) - - - 5.455e-246 765.0
HFD2_k127_288786_20 FR47-like protein - - - 0.00000000000000000000000001007 115.0
HFD2_k127_288786_21 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000001252 70.0
HFD2_k127_288786_22 dehydratase K03335 - 4.2.1.44 0.0000000073 67.0
HFD2_k127_288786_23 Domain of unknown function (DUF2520) - - - 0.00000001193 65.0
HFD2_k127_288786_24 - - - - 0.00008354 49.0
HFD2_k127_288786_3 ATPase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 573.0
HFD2_k127_288786_4 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 553.0
HFD2_k127_288786_5 iron-nicotianamine transmembrane transporter activity - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 525.0
HFD2_k127_288786_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 515.0
HFD2_k127_288786_7 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 483.0
HFD2_k127_288786_8 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 475.0
HFD2_k127_288786_9 COG3119 Arylsulfatase A and related enzymes K01137 - 3.1.6.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000934 435.0
HFD2_k127_2902924_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 608.0
HFD2_k127_2902924_1 Glycosyl hydrolase catalytic core - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 522.0
HFD2_k127_2902924_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 500.0
HFD2_k127_2902924_3 Protein of unknown function (DUF1698) K15257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 379.0
HFD2_k127_2902924_4 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 368.0
HFD2_k127_2902924_5 protein domain associated with - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001004 269.0
HFD2_k127_2902924_6 Histidine kinase A domain protein - - - 0.000000003732 62.0
HFD2_k127_2905526_0 Belongs to the ClpA ClpB family K03696 - - 0.0 1483.0
HFD2_k127_2905526_1 amine dehydrogenase activity - - - 0.0 1110.0
HFD2_k127_2905526_10 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 377.0
HFD2_k127_2905526_11 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 378.0
HFD2_k127_2905526_12 PFAM SAF domain K02279 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 337.0
HFD2_k127_2905526_13 response regulator K02479,K07684,K07685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 335.0
HFD2_k127_2905526_14 type II secretion system K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 342.0
HFD2_k127_2905526_15 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000158 240.0
HFD2_k127_2905526_17 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000004815 186.0
HFD2_k127_2905526_18 - - - - 0.000000000000000000000000000000000000000000000001976 183.0
HFD2_k127_2905526_19 Type IV leader peptidase family K02278 - 3.4.23.43 0.000000000000000000000000000000000000000005524 172.0
HFD2_k127_2905526_2 PFAM type II secretion system protein E K02283 - - 1.217e-249 777.0
HFD2_k127_2905526_20 TadE-like protein - - - 0.0000000000000000000000000000000000000000157 158.0
HFD2_k127_2905526_21 Sulfatase - - - 0.000000000000000000000000000000000000006823 164.0
HFD2_k127_2905526_22 Beta-L-arabinofuranosidase, GH127 - - - 0.0000000000000000000000000000000002143 153.0
HFD2_k127_2905526_23 PFAM TadE family protein - - - 0.0000000000000000000000000000002813 127.0
HFD2_k127_2905526_25 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000002674 115.0
HFD2_k127_2905526_26 ioli protein K06606 - 5.3.99.11 0.00000000000000000003946 102.0
HFD2_k127_2905526_27 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000009907 91.0
HFD2_k127_2905526_28 exo-alpha-(2->6)-sialidase activity - - - 0.0000000005066 72.0
HFD2_k127_2905526_29 PFAM Flp Fap pilin component K02651 - - 0.000001554 55.0
HFD2_k127_2905526_3 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 629.0
HFD2_k127_2905526_30 PFAM Flp Fap pilin component K02651 - - 0.000006976 50.0
HFD2_k127_2905526_31 phosphoesterase, PA-phosphatase related - - - 0.00001126 49.0
HFD2_k127_2905526_4 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 602.0
HFD2_k127_2905526_5 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 580.0
HFD2_k127_2905526_6 Belongs to the GSP D family K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005623 559.0
HFD2_k127_2905526_7 AAA domain K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 534.0
HFD2_k127_2905526_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 445.0
HFD2_k127_2905526_9 type II secretion system K12510 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 399.0
HFD2_k127_293906_0 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 322.0
HFD2_k127_293906_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000001017 194.0
HFD2_k127_293906_2 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000002607 178.0
HFD2_k127_2940412_0 cellulose binding - - - 3.016e-222 696.0
HFD2_k127_2940412_1 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 4.257e-217 684.0
HFD2_k127_2940412_10 Thioesterase superfamily - - - 0.000000000000000005718 89.0
HFD2_k127_2940412_11 - - - - 0.00000000000001117 76.0
HFD2_k127_2940412_13 Protein of unknown function (DUF2662) - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.000000002029 70.0
HFD2_k127_2940412_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 627.0
HFD2_k127_2940412_3 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 329.0
HFD2_k127_2940412_4 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K19715 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0043170,GO:0044238,GO:0071704,GO:1901576 2.6.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008231 306.0
HFD2_k127_2940412_5 Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003196 248.0
HFD2_k127_2940412_6 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000001457 151.0
HFD2_k127_2940412_7 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.000000000000000000000000000000000003102 154.0
HFD2_k127_2940412_8 Lytic transglycosylase catalytic K08307 - - 0.000000000000000000000000000003452 138.0
HFD2_k127_2973015_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1146.0
HFD2_k127_2973015_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 2.519e-287 889.0
HFD2_k127_2973015_2 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007831 475.0
HFD2_k127_2973015_3 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 375.0
HFD2_k127_2973015_4 methyltransferase activity K21310 - 2.1.1.334 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 298.0
HFD2_k127_2973015_5 PIN domain - - - 0.00000000000000000000000000000000000009987 148.0
HFD2_k127_2987749_0 Baseplate J-like protein - - - 5.551e-283 885.0
HFD2_k127_2987749_1 Phage tail sheath protein K06907 - - 4.981e-247 790.0
HFD2_k127_2987749_10 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009091 323.0
HFD2_k127_2987749_11 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 304.0
HFD2_k127_2987749_12 PFAM ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005444 278.0
HFD2_k127_2987749_13 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007048 239.0
HFD2_k127_2987749_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009148 255.0
HFD2_k127_2987749_15 Alanine racemase, N-terminal domain K18425,K19967 - 4.1.2.42,4.1.3.41 0.000000000000000000000000000000000000000000000000000000000000000000002093 251.0
HFD2_k127_2987749_16 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000000000000000000000001948 220.0
HFD2_k127_2987749_17 Protein of unknown function (DUF4255) - - - 0.000000000000000000000000000000000000000000000000000000000002137 217.0
HFD2_k127_2987749_18 base plate protein gp25 of Bacteriophage K06903 - - 0.0000000000000000000000000000000000000000000000002407 180.0
HFD2_k127_2987749_19 WHG domain - - - 0.000000000000000000000000000000000001564 145.0
HFD2_k127_2987749_2 Phage tail protein (Tail_P2_I) - - - 2.354e-233 744.0
HFD2_k127_2987749_21 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15548 GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015546,GO:0015893,GO:0015906,GO:0022857,GO:0042221,GO:0042493,GO:0042886,GO:0042887,GO:0042891,GO:0042895,GO:0042908,GO:0042910,GO:0045117,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0072348,GO:1901474,GO:1901682,GO:1902599 - 0.0000000005367 71.0
HFD2_k127_2987749_3 Phage tail sheath C-terminal domain - - - 3.46e-229 726.0
HFD2_k127_2987749_4 PFAM AAA ATPase central domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 494.0
HFD2_k127_2987749_5 Phage late control gene D protein (GPD) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 476.0
HFD2_k127_2987749_6 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 426.0
HFD2_k127_2987749_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 400.0
HFD2_k127_2987749_8 protein and some similarities with VgrG protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 316.0
HFD2_k127_2987749_9 Sigma-54 interaction domain K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 323.0
HFD2_k127_2992218_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 601.0
HFD2_k127_2992218_1 Glycosyltransferase family 20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 509.0
HFD2_k127_2992218_10 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000007948 260.0
HFD2_k127_2992218_11 BNR repeat-like domain K05989 - 3.2.1.40 0.000000000000000000000000000000000000000000000008882 175.0
HFD2_k127_2992218_12 low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000000000000000000000000000000000000005598 166.0
HFD2_k127_2992218_13 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000006948 161.0
HFD2_k127_2992218_14 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000000000000001944 151.0
HFD2_k127_2992218_15 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.000000000000000000000000006671 113.0
HFD2_k127_2992218_2 Belongs to the LDH2 MDH2 oxidoreductase family K08092 - 1.1.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 495.0
HFD2_k127_2992218_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 478.0
HFD2_k127_2992218_4 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 460.0
HFD2_k127_2992218_5 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 456.0
HFD2_k127_2992218_6 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 403.0
HFD2_k127_2992218_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005308 273.0
HFD2_k127_2992218_8 PFAM ATP-binding region, ATPase domain protein domain protein K07683 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001027 282.0
HFD2_k127_2992218_9 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006039 270.0
HFD2_k127_3015141_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1399.0
HFD2_k127_3015141_1 protein kinase activity K12132 - 2.7.11.1 0.0 1194.0
HFD2_k127_3015141_10 Histidine kinase HAMP K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006547 409.0
HFD2_k127_3015141_11 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008122 390.0
HFD2_k127_3015141_12 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 371.0
HFD2_k127_3015141_13 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 364.0
HFD2_k127_3015141_14 Belongs to the NiFe NiFeSe hydrogenase large subunit family K14126,K17993 GO:0003674,GO:0005488,GO:0005575,GO:0016151,GO:0032991,GO:0043167,GO:0043169,GO:0044569,GO:0046872,GO:0046914,GO:1902494 1.12.1.3,1.12.1.5,1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000417 332.0
HFD2_k127_3015141_15 Oxidoreductase NAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 310.0
HFD2_k127_3015141_16 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 292.0
HFD2_k127_3015141_17 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 297.0
HFD2_k127_3015141_18 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003572 257.0
HFD2_k127_3015141_19 DNA-templated transcription, initiation K02405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002664 245.0
HFD2_k127_3015141_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 1.591e-254 790.0
HFD2_k127_3015141_20 NADH ubiquinone oxidoreductase 20 kDa subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000019 222.0
HFD2_k127_3015141_21 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000008087 227.0
HFD2_k127_3015141_22 metal cluster binding - - - 0.00000000000000000000000000000000000000000000000000000003546 202.0
HFD2_k127_3015141_23 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000000000001316 175.0
HFD2_k127_3015141_25 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.0000000000000000000000000000001845 128.0
HFD2_k127_3015141_26 PFAM response regulator receiver - - - 0.000000000000000000004852 97.0
HFD2_k127_3015141_27 cheY-homologous receiver domain - - - 0.00000000000000004502 87.0
HFD2_k127_3015141_28 Hydrogenase maturation protease K03605 - - 0.0000000000000001309 88.0
HFD2_k127_3015141_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 6.921e-254 792.0
HFD2_k127_3015141_4 Belongs to the peptidase M16 family - - - 1.873e-228 713.0
HFD2_k127_3015141_5 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006769 609.0
HFD2_k127_3015141_6 Belongs to the purine-cytosine permease (2.A.39) family K10974 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 599.0
HFD2_k127_3015141_7 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 591.0
HFD2_k127_3015141_8 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 548.0
HFD2_k127_3015141_9 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 446.0
HFD2_k127_3038906_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1142.0
HFD2_k127_3038906_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 4.05e-322 992.0
HFD2_k127_3038906_10 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 311.0
HFD2_k127_3038906_11 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003959 291.0
HFD2_k127_3038906_12 - K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005747 271.0
HFD2_k127_3038906_13 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K21103,K21460 - 2.1.1.304,2.1.1.327 0.00000000000000000000000000000000000000000000000000000000000000000111 245.0
HFD2_k127_3038906_14 PFAM oxidoreductase domain protein K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000000000000000000000000000798 240.0
HFD2_k127_3038906_15 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000002219 229.0
HFD2_k127_3038906_16 PFAM Lytic transglycosylase catalytic - - - 0.000000000000000000000000000000000000000000000001026 182.0
HFD2_k127_3038906_17 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000002244 166.0
HFD2_k127_3038906_18 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000009142 160.0
HFD2_k127_3038906_19 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000007039 150.0
HFD2_k127_3038906_2 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.438e-294 911.0
HFD2_k127_3038906_20 photosynthesis K02656 - - 0.000000000000000000000000000000002791 132.0
HFD2_k127_3038906_21 TIGRFAM TonB family K03832 - - 0.00000000000000000000000000000004102 133.0
HFD2_k127_3038906_22 Domain of unknown function (DUF4160) - - - 0.00000000000000000000000000005874 117.0
HFD2_k127_3038906_23 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000004204 109.0
HFD2_k127_3038906_24 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.000000000000001962 84.0
HFD2_k127_3038906_25 BlaR1 peptidase M56 - - - 0.000000000000003901 83.0
HFD2_k127_3038906_26 Heparinase II/III-like protein - - - 0.000000001507 72.0
HFD2_k127_3038906_27 Protein of unknown function (DUF2442) - - - 0.000000003769 61.0
HFD2_k127_3038906_3 Methyltransferase domain - - - 2.416e-237 742.0
HFD2_k127_3038906_4 Carboxypeptidase regulatory-like domain - - - 1.672e-226 747.0
HFD2_k127_3038906_5 TIGRFAM Threonine synthase K01733 - 4.2.3.1 5.343e-206 648.0
HFD2_k127_3038906_6 tRNA-splicing ligase that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009473 539.0
HFD2_k127_3038906_7 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 512.0
HFD2_k127_3038906_8 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 439.0
HFD2_k127_3038906_9 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 313.0
HFD2_k127_309657_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 308.0
HFD2_k127_309657_1 - - - - 0.00000000000000000008667 102.0
HFD2_k127_3108624_0 Sulfatase - - - 1.746e-253 795.0
HFD2_k127_3108624_1 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 449.0
HFD2_k127_3108624_2 arylsulfatase activity K01135,K01138 - 3.1.6.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 364.0
HFD2_k127_3108624_3 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 358.0
HFD2_k127_3108624_4 Trehalose utilisation K09992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 308.0
HFD2_k127_3108624_5 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003302 275.0
HFD2_k127_3108624_6 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003523 272.0
HFD2_k127_3108624_7 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001439 268.0
HFD2_k127_3108624_8 Domain of unknown function (DUF296) K06934 - - 0.0000000000000000000000000009318 119.0
HFD2_k127_3108624_9 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000001389 118.0
HFD2_k127_3110446_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1459.0
HFD2_k127_3110446_1 Belongs to the IlvD Edd family K22396 - 4.2.1.82 0.0 1025.0
HFD2_k127_3110446_10 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009095 616.0
HFD2_k127_3110446_11 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 605.0
HFD2_k127_3110446_12 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 570.0
HFD2_k127_3110446_13 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009134 561.0
HFD2_k127_3110446_14 Cobalamin-independent synthase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000636 529.0
HFD2_k127_3110446_15 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008249 503.0
HFD2_k127_3110446_16 BNR repeat-like domain K01186 - 3.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 442.0
HFD2_k127_3110446_17 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 430.0
HFD2_k127_3110446_18 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351 419.0
HFD2_k127_3110446_19 PFAM Alpha beta hydrolase K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005033 417.0
HFD2_k127_3110446_2 Voltage gated chloride channel K03281 - - 4.02e-286 907.0
HFD2_k127_3110446_20 TIGRFAM diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 396.0
HFD2_k127_3110446_21 metallopeptidase activity K06212,K06402 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031224,GO:0031226,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 393.0
HFD2_k127_3110446_22 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 379.0
HFD2_k127_3110446_23 PFAM ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006418 367.0
HFD2_k127_3110446_24 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 350.0
HFD2_k127_3110446_25 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 361.0
HFD2_k127_3110446_26 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007879 350.0
HFD2_k127_3110446_27 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 323.0
HFD2_k127_3110446_28 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 326.0
HFD2_k127_3110446_29 carboxymethylenebutenolidase activity K01061,K06889 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 314.0
HFD2_k127_3110446_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 4.974e-241 751.0
HFD2_k127_3110446_30 Ferric uptake regulator family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 284.0
HFD2_k127_3110446_31 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003903 280.0
HFD2_k127_3110446_32 SIS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003577 255.0
HFD2_k127_3110446_33 Protein of unknown function, DUF480 K09915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002494 250.0
HFD2_k127_3110446_34 PFAM Single-stranded nucleic acid binding R3H K06346 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003651 245.0
HFD2_k127_3110446_35 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000004427 237.0
HFD2_k127_3110446_36 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000006878 241.0
HFD2_k127_3110446_37 Alkaline phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000001291 237.0
HFD2_k127_3110446_38 - - - - 0.0000000000000000000000000000000000000000000000000000000000008016 219.0
HFD2_k127_3110446_39 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000004081 211.0
HFD2_k127_3110446_4 inositol 2-dehydrogenase activity - - - 1.218e-230 720.0
HFD2_k127_3110446_40 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000000000000000001115 212.0
HFD2_k127_3110446_41 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000000000000000000000000000000000000006478 212.0
HFD2_k127_3110446_42 - - - - 0.000000000000000000000000000000000000000000000000008963 186.0
HFD2_k127_3110446_43 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000001267 184.0
HFD2_k127_3110446_45 Protein of unknown function (DUF721) - - - 0.000000000000000000000000000000000000002592 150.0
HFD2_k127_3110446_46 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000005208 139.0
HFD2_k127_3110446_47 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000004219 127.0
HFD2_k127_3110446_48 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000008954 128.0
HFD2_k127_3110446_49 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000001893 111.0
HFD2_k127_3110446_5 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 1.984e-214 679.0
HFD2_k127_3110446_50 peroxiredoxin activity K03386,K03564,K16922 - 1.11.1.15 0.00000000000000000004843 93.0
HFD2_k127_3110446_51 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000000006991 87.0
HFD2_k127_3110446_52 - - - - 0.00000000000000005085 85.0
HFD2_k127_3110446_53 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000009356 86.0
HFD2_k127_3110446_56 PFAM AhpC TSA family K03564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.11.1.15 0.00000009259 56.0
HFD2_k127_3110446_6 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 7.35e-198 627.0
HFD2_k127_3110446_7 Inner membrane component of T3SS, cytoplasmic domain - - - 1.283e-195 634.0
HFD2_k127_3110446_8 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 615.0
HFD2_k127_3110446_9 PhoPQ-activated pathogenicity-related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007324 608.0
HFD2_k127_3127799_0 Carboxypeptidase regulatory-like domain - - - 0.0 1082.0
HFD2_k127_3127799_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 3.698e-229 714.0
HFD2_k127_3127799_10 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 337.0
HFD2_k127_3127799_11 Phosphate acetyl/butaryl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 291.0
HFD2_k127_3127799_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 290.0
HFD2_k127_3127799_13 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004322 273.0
HFD2_k127_3127799_14 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002184 272.0
HFD2_k127_3127799_15 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001696 252.0
HFD2_k127_3127799_16 - - - - 0.00000000000000000000000000000000000000000000000000000001312 202.0
HFD2_k127_3127799_17 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000001053 185.0
HFD2_k127_3127799_18 Recombinase - - - 0.0000000000000000000000000000000004121 147.0
HFD2_k127_3127799_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.998e-216 678.0
HFD2_k127_3127799_20 RNA recognition motif - - - 0.000000000000000000000007874 109.0
HFD2_k127_3127799_3 Sigma-54 interaction domain K15836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 621.0
HFD2_k127_3127799_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 533.0
HFD2_k127_3127799_5 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649,K02594 - 2.3.3.13,2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009905 433.0
HFD2_k127_3127799_6 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 394.0
HFD2_k127_3127799_7 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 376.0
HFD2_k127_3127799_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009301 385.0
HFD2_k127_3127799_9 von Willebrand factor type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 355.0
HFD2_k127_3143781_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0 1105.0
HFD2_k127_3143781_1 allophanate hydrolase subunit 2 K01941,K06350 - 6.3.4.6 2.86e-291 932.0
HFD2_k127_3143781_10 Domain of unknown function (DUF4962) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005234 328.0
HFD2_k127_3143781_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001483 243.0
HFD2_k127_3143781_12 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000537 203.0
HFD2_k127_3143781_15 Phage derived protein Gp49-like (DUF891) - - - 0.000000000000000000000000004075 116.0
HFD2_k127_3143781_16 - - - - 0.00000000000000000000000001818 120.0
HFD2_k127_3143781_17 Tetratricopeptide repeat - - - 0.000000438 63.0
HFD2_k127_3143781_2 Fumarate hydratase (Fumerase) K01676 - 4.2.1.2 2.583e-268 861.0
HFD2_k127_3143781_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 4.892e-265 826.0
HFD2_k127_3143781_4 Tetratricopeptide TPR_2 repeat protein - - - 7.721e-203 669.0
HFD2_k127_3143781_5 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008504 597.0
HFD2_k127_3143781_6 amidohydrolase K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 580.0
HFD2_k127_3143781_7 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 480.0
HFD2_k127_3143781_8 cytochrome C peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 471.0
HFD2_k127_3143781_9 Domain of Unknown Function (DUF1080) K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 382.0
HFD2_k127_3191762_0 efflux transmembrane transporter activity - - - 9.463e-310 975.0
HFD2_k127_3191762_1 beta-galactosidase activity K01190,K12308 - 3.2.1.23 1.348e-284 891.0
HFD2_k127_3191762_11 Protein of unknown function (DUF2934) - - - 0.0000000003059 65.0
HFD2_k127_3191762_2 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 553.0
HFD2_k127_3191762_3 Peptidase S8 K01342,K08651 - 3.4.21.62,3.4.21.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 469.0
HFD2_k127_3191762_4 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 402.0
HFD2_k127_3191762_5 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 322.0
HFD2_k127_3191762_6 Belongs to the glycosyl hydrolase 5 (cellulase A) family K19355 - 3.2.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 301.0
HFD2_k127_3191762_7 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000001565 242.0
HFD2_k127_3191762_8 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000004919 218.0
HFD2_k127_3191762_9 - - - - 0.000000000000000003824 91.0
HFD2_k127_3202765_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008872 361.0
HFD2_k127_3202765_1 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 345.0
HFD2_k127_3202765_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000001655 235.0
HFD2_k127_3202765_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000000000000000006366 193.0
HFD2_k127_3202765_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000002259 86.0
HFD2_k127_321829_0 Histidine Phosphotransfer domain K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 473.0
HFD2_k127_321829_1 Methyl-accepting chemotaxis protein (MCP) signaling domain K02660,K03406 - - 0.00000000000000000000006779 100.0
HFD2_k127_3241864_0 TIGRFAM flagellar hook-associated protein FlgK K02396 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007789 370.0
HFD2_k127_3241864_1 Bacterial flagellin N-terminal helical region K02397 - - 0.00000000000000000000000000000000000000000000000000000000000004379 225.0
HFD2_k127_3241864_2 flagellar motor switch protein K02416 - - 0.000000000168 73.0
HFD2_k127_3246507_0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 3.747e-282 884.0
HFD2_k127_3246507_1 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 1.415e-252 788.0
HFD2_k127_3246507_10 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 421.0
HFD2_k127_3246507_11 Two component regulator three Y domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 445.0
HFD2_k127_3246507_12 response to abiotic stimulus K21440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004196 413.0
HFD2_k127_3246507_13 Aminotransferase class-V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 407.0
HFD2_k127_3246507_14 SRP54-type protein, GTPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 394.0
HFD2_k127_3246507_15 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 354.0
HFD2_k127_3246507_16 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 321.0
HFD2_k127_3246507_17 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001922 293.0
HFD2_k127_3246507_18 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004881 276.0
HFD2_k127_3246507_19 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002902 280.0
HFD2_k127_3246507_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 1.5e-251 819.0
HFD2_k127_3246507_20 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000003559 183.0
HFD2_k127_3246507_21 Glycine cleavage H-protein - - - 0.0000000000000000000000000000000000000000000002321 179.0
HFD2_k127_3246507_23 - - - - 0.00000000000000000000000000601 126.0
HFD2_k127_3246507_24 PAS domain - - - 0.0000000000000000000000000279 113.0
HFD2_k127_3246507_25 HDOD domain - - - 0.0000000000000000000000002117 119.0
HFD2_k127_3246507_26 beta-subunit of geranylgeranyltransferase or farnesyltransferase K05956 - 2.5.1.60 0.0000000000000000007394 97.0
HFD2_k127_3246507_27 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.000000000000000003757 93.0
HFD2_k127_3246507_28 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.00000000000000005617 84.0
HFD2_k127_3246507_29 - - - - 0.000000000000002445 77.0
HFD2_k127_3246507_3 - - - - 1.453e-241 788.0
HFD2_k127_3246507_30 OsmC-like protein - - - 0.000000000001617 70.0
HFD2_k127_3246507_31 Pas domain K02282 - - 0.00000000004825 72.0
HFD2_k127_3246507_32 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.0000000006251 62.0
HFD2_k127_3246507_33 PFAM ATP-binding region, ATPase domain protein domain protein - - - 0.000000001453 63.0
HFD2_k127_3246507_34 Serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.000003565 60.0
HFD2_k127_3246507_4 Protein of unknown function DUF116 - - - 6.592e-216 688.0
HFD2_k127_3246507_5 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 4.676e-209 681.0
HFD2_k127_3246507_6 Squalene-hopene cyclase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 596.0
HFD2_k127_3246507_7 enzyme of the MoaA nifB pqqE family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 537.0
HFD2_k127_3246507_8 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 490.0
HFD2_k127_3246507_9 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 424.0
HFD2_k127_3246732_0 Glycosyl hydrolases family 2, TIM barrel domain - - - 2.522e-221 701.0
HFD2_k127_3246732_1 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009318 542.0
HFD2_k127_3246732_10 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000001087 176.0
HFD2_k127_3246732_11 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000008677 135.0
HFD2_k127_3246732_12 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0005538 45.0
HFD2_k127_3246732_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 537.0
HFD2_k127_3246732_3 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 497.0
HFD2_k127_3246732_4 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 440.0
HFD2_k127_3246732_5 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 415.0
HFD2_k127_3246732_6 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 305.0
HFD2_k127_3246732_7 PFAM Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 294.0
HFD2_k127_3246732_8 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001704 274.0
HFD2_k127_3246732_9 YbbR-like protein - - - 0.00000000000000000000000000000000000000000000000001168 188.0
HFD2_k127_3249293_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 479.0
HFD2_k127_3249293_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000001223 171.0
HFD2_k127_325367_0 Surface antigen variable number K07277 - - 0.0 1443.0
HFD2_k127_325367_1 RNA polymerase sigma-54 factor K03092 - - 3.619e-262 821.0
HFD2_k127_325367_11 - - - - 0.000000000000000000000000000000000000000000000000006736 189.0
HFD2_k127_325367_12 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000002075 153.0
HFD2_k127_325367_13 Cupin domain - - - 0.0000000000000000000000000000000000544 146.0
HFD2_k127_325367_14 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000008746 145.0
HFD2_k127_325367_15 Helix-turn-helix XRE-family like proteins - - - 0.000000000002451 70.0
HFD2_k127_325367_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 481.0
HFD2_k127_325367_3 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 430.0
HFD2_k127_325367_4 PFAM Phenazine biosynthesis PhzC PhzF protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 357.0
HFD2_k127_325367_5 membrane-bound metal-dependent hydrolase K07038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 340.0
HFD2_k127_325367_7 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001513 247.0
HFD2_k127_325367_8 Outer membrane protein (OmpH-like) K06142 - - 0.000000000000000000000000000000000000000000000000000000000000000000009023 240.0
HFD2_k127_325367_9 regulation of translation K05808,K05809 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006446,GO:0006448,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000003902 208.0
HFD2_k127_3264567_0 PFAM NHL repeat containing protein - - - 9.43e-235 779.0
HFD2_k127_3264567_1 Bacterial membrane protein, YfhO - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 511.0
HFD2_k127_3264567_2 protein import - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000916 391.0
HFD2_k127_3264567_3 regulation of ruffle assembly - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001482 289.0
HFD2_k127_3264567_4 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000001443 125.0
HFD2_k127_3264567_7 cheY-homologous receiver domain - - - 0.00000000000001667 82.0
HFD2_k127_3264567_8 PFAM glycosyl transferase family 39 K14340 - - 0.00008544 47.0
HFD2_k127_3280062_0 Cytochrome c, class I - - - 6.4e-222 713.0
HFD2_k127_3280062_1 arylsulfatase activity - - - 3.496e-196 623.0
HFD2_k127_3280062_2 arylsulfatase activity K01133 - 3.1.6.6 0.00000000000000000000000000000006453 129.0
HFD2_k127_3333834_0 ABC transporter, ATP-binding protein - - - 1.922e-207 664.0
HFD2_k127_3333834_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008989 549.0
HFD2_k127_3333834_10 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000002538 57.0
HFD2_k127_3333834_2 nucleic acid binding K03698 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 505.0
HFD2_k127_3333834_3 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 497.0
HFD2_k127_3333834_4 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 475.0
HFD2_k127_3333834_5 peptidyl-prolyl cis-trans isomerase activity K03769,K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 441.0
HFD2_k127_3333834_6 Glycosyl transferase, family 2 K00786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 376.0
HFD2_k127_3333834_7 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000000004874 146.0
HFD2_k127_3333834_9 PFAM type IV pilus assembly PilZ - - - 0.0000000000000000006351 92.0
HFD2_k127_3340244_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 518.0
HFD2_k127_3340244_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000002794 239.0
HFD2_k127_3340244_2 Belongs to the purine-cytosine permease (2.A.39) family - - - 0.00000000000000000003153 93.0
HFD2_k127_3475628_0 - - - - 0.000000000000000000000000000000000000000000000000000007063 199.0
HFD2_k127_3475628_1 Domain of unknown function (DUF362) - - - 0.00003488 50.0
HFD2_k127_3512054_0 Zinc metalloprotease (Elastase) K08603 - 3.4.24.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 405.0
HFD2_k127_3512054_1 Methane oxygenase PmoA - - - 0.000000000000000000000000000000000000000000000000000000000000000000003304 239.0
HFD2_k127_3512742_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 0.0 1105.0
HFD2_k127_3512742_1 Carboxypeptidase regulatory-like domain - - - 2.721e-305 972.0
HFD2_k127_3512742_2 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 9.504e-234 736.0
HFD2_k127_3512742_3 COG2133 Glucose sorbosone dehydrogenases - - - 2.991e-207 657.0
HFD2_k127_3512742_4 pyrroloquinoline quinone binding - - - 1.33e-204 647.0
HFD2_k127_3512742_5 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 588.0
HFD2_k127_3512742_6 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 435.0
HFD2_k127_3512742_7 protocatechuate 3,4-dioxygenase activity K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003603 278.0
HFD2_k127_3528822_0 COG2801 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 451.0
HFD2_k127_3528822_1 Phage integrase, N-terminal SAM-like domain - - - 0.000000000000000000000000000000000000009005 155.0
HFD2_k127_3528822_2 COG2801 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000001452 145.0
HFD2_k127_353124_0 PFAM glycoside hydrolase family 3 K05349 - 3.2.1.21 4.23e-321 999.0
HFD2_k127_353124_1 DNA ligase D, 3'-phosphoesterase domain K01971 - 6.5.1.1 1.189e-301 948.0
HFD2_k127_353124_10 PFAM FAD linked oxidase domain protein K11472 - - 0.0000000000000000000000000000000000000000000000000000000000002453 226.0
HFD2_k127_353124_11 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000000000007004 124.0
HFD2_k127_353124_2 Putative glucoamylase - - - 8.022e-213 670.0
HFD2_k127_353124_3 PA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 584.0
HFD2_k127_353124_4 Cysteine-rich domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 538.0
HFD2_k127_353124_5 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 487.0
HFD2_k127_353124_6 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 418.0
HFD2_k127_353124_7 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 437.0
HFD2_k127_353124_8 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 359.0
HFD2_k127_353124_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006828 353.0
HFD2_k127_3533410_0 ABC transporter transmembrane K18890 - - 2.916e-298 923.0
HFD2_k127_3533410_1 Belongs to the carbamoyltransferase HypF family K04656 - - 4.019e-227 725.0
HFD2_k127_3533410_10 - - - - 0.0000000000000000000000000000000000000000000000000000004937 208.0
HFD2_k127_3533410_12 - - - - 0.0000000000000000000000000001886 119.0
HFD2_k127_3533410_13 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.0000000000000000000000004184 106.0
HFD2_k127_3533410_14 Cysteine-rich domain K11473 - - 0.0000000000000000000007101 95.0
HFD2_k127_3533410_2 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000482 522.0
HFD2_k127_3533410_3 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 496.0
HFD2_k127_3533410_4 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 489.0
HFD2_k127_3533410_5 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 467.0
HFD2_k127_3533410_6 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 464.0
HFD2_k127_3533410_7 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 436.0
HFD2_k127_3533410_8 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 415.0
HFD2_k127_3533410_9 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000000000000001567 197.0
HFD2_k127_3549670_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 1.189e-261 814.0
HFD2_k127_3549670_1 amine dehydrogenase activity - - - 0.00000001645 60.0
HFD2_k127_3552509_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008512 572.0
HFD2_k127_3552509_1 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 368.0
HFD2_k127_3552509_2 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 308.0
HFD2_k127_3552509_3 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 297.0
HFD2_k127_3552509_4 PKD domain containing protein K01337,K20276,K21449 - 3.4.21.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002698 290.0
HFD2_k127_3552509_5 proteolysis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000189 254.0
HFD2_k127_3552509_6 N-acetylglucosaminylinositol deacetylase activity - - - 0.0000000000000000000000000000000000000000000000774 183.0
HFD2_k127_3552509_7 - - - - 0.00000000000000000000000000000000000002541 150.0
HFD2_k127_3552509_8 Domain of unknown function (DUF4870) - - - 0.000000000000000000000000000000000001654 146.0
HFD2_k127_3574145_0 choline dehydrogenase activity - - - 4.394e-277 861.0
HFD2_k127_3574145_1 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007853 321.0
HFD2_k127_3574145_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000002609 161.0
HFD2_k127_3574145_3 DinB family - - - 0.000000000000000000000000004903 119.0
HFD2_k127_3574145_4 Transport and Golgi organisation 2 - - - 0.00000000000000000000000003346 119.0
HFD2_k127_360208_0 Carboxypeptidase regulatory-like domain - - - 0.0 1095.0
HFD2_k127_360208_1 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002052 267.0
HFD2_k127_360208_2 Beta-lactamase superfamily domain K03476 - - 0.000000000000000000000000000000000000000000000000000000000000000000006607 243.0
HFD2_k127_360208_3 Pfam 2OG-Fe(II) oxygenase - - - 0.000000000000000000000000000000000000000000000000000001131 198.0
HFD2_k127_360208_4 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000002101 170.0
HFD2_k127_360208_5 PFAM secretion protein HlyD family protein K02005,K02022 - - 0.000000000000000000000000000000000000000891 163.0
HFD2_k127_360208_6 energy transducer activity - - - 0.00000000000000000000000000000000003089 151.0
HFD2_k127_360208_7 Chromate transporter K07240 - - 0.0000000000000000000000000000000002479 138.0
HFD2_k127_360208_8 PFAM type IV pilus assembly PilZ - - - 0.0000000000000000000000698 103.0
HFD2_k127_360259_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 4.087e-308 960.0
HFD2_k127_360259_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 1.192e-209 656.0
HFD2_k127_360259_2 AP endonuclease family 2 C terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 568.0
HFD2_k127_360259_3 PFAM Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 565.0
HFD2_k127_360259_4 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 462.0
HFD2_k127_360259_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 435.0
HFD2_k127_360259_6 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 323.0
HFD2_k127_360259_7 PFAM Neutral alkaline nonlysosomal ceramidase - - - 0.000000000000000000000000000000000000119 149.0
HFD2_k127_360259_8 PFAM Neutral alkaline nonlysosomal ceramidase - - - 0.0000000000000000000000000000000001511 150.0
HFD2_k127_360259_9 Sigma-70 region 3 K02405 - - 0.000000000000000000000000000000003845 139.0
HFD2_k127_3606086_0 Transposase - - - 2.732e-202 637.0
HFD2_k127_3606086_1 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000001031 212.0
HFD2_k127_3606086_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.00000000000000000000001104 101.0
HFD2_k127_3623405_0 TonB-dependent receptor - - - 0.0 1262.0
HFD2_k127_3623405_1 Carboxypeptidase regulatory-like domain - - - 6.126e-204 674.0
HFD2_k127_3623405_10 aldo-keto reductase (NADP) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 379.0
HFD2_k127_3623405_11 CYTH K05873 - 4.6.1.1 0.000000000000000000000000000000000000000000001405 171.0
HFD2_k127_3623405_12 UMP catabolic process - - - 0.00000004794 65.0
HFD2_k127_3623405_14 - - - - 0.000003942 61.0
HFD2_k127_3623405_2 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 8.369e-197 630.0
HFD2_k127_3623405_3 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 537.0
HFD2_k127_3623405_4 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008737 528.0
HFD2_k127_3623405_5 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 545.0
HFD2_k127_3623405_6 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 510.0
HFD2_k127_3623405_7 COG1073 Hydrolases of the alpha beta superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 506.0
HFD2_k127_3623405_8 thiamine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000895 417.0
HFD2_k127_3623405_9 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 411.0
HFD2_k127_3645638_0 transport - - - 0.0 1071.0
HFD2_k127_3645638_1 Protein of unknown function (DUF1553) - - - 4.732e-231 732.0
HFD2_k127_3645638_10 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 329.0
HFD2_k127_3645638_11 PFAM Rhodanese domain protein K03892 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000033 276.0
HFD2_k127_3645638_12 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000002462 234.0
HFD2_k127_3645638_13 thiosulfate sulfurtransferase activity - - - 0.00000000000000000000000000000000000000000000001332 176.0
HFD2_k127_3645638_15 Protein of unknown function (DUF1501) - - - 0.000000000000002389 79.0
HFD2_k127_3645638_16 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0034214,GO:0042802,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051259,GO:0065003,GO:0071840 - 0.0001843 46.0
HFD2_k127_3645638_2 Peptidase family M49 - - - 4.093e-226 723.0
HFD2_k127_3645638_3 Beta-L-arabinofuranosidase, GH127 K09955 - - 4.487e-194 619.0
HFD2_k127_3645638_4 PFAM Peptidase S41 K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 531.0
HFD2_k127_3645638_5 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 550.0
HFD2_k127_3645638_6 TrkA-C domain K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008347 498.0
HFD2_k127_3645638_7 Beta-eliminating lyase K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 490.0
HFD2_k127_3645638_8 beta-fructofuranosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 362.0
HFD2_k127_3645638_9 oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 364.0
HFD2_k127_3653032_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.878e-314 973.0
HFD2_k127_3653032_1 Penicillin binding protein transpeptidase domain - - - 0.000000000000000000000000000000000000000000001737 175.0
HFD2_k127_3661555_0 phospholipase C - - - 0.000000000000000000000000000000000000000000000000000001033 194.0
HFD2_k127_3661555_1 Belongs to the globin family K05916 - 1.14.12.17 0.0000000000000000000000006791 113.0
HFD2_k127_3671643_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 2.811e-286 896.0
HFD2_k127_3671643_1 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 529.0
HFD2_k127_3671643_2 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 424.0
HFD2_k127_3671643_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003516 271.0
HFD2_k127_3702097_0 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 426.0
HFD2_k127_3702097_1 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000742 324.0
HFD2_k127_3707215_0 Melibiase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 519.0
HFD2_k127_3707215_1 Pectate lyase K21606 - 3.2.1.202 0.00000000000000006666 94.0
HFD2_k127_3707215_2 Alpha-L-arabinofuranosidase K01209 - 3.2.1.55 0.000000000001982 75.0
HFD2_k127_3707215_4 Phosphoesterase family K01114 - 3.1.4.3 0.00000149 62.0
HFD2_k127_3712989_0 Galactose oxidase, central domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007669 332.0
HFD2_k127_3732362_1 PFAM Major Facilitator Superfamily K08191 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002151 280.0
HFD2_k127_3732362_2 PFAM Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000000003623 178.0
HFD2_k127_3751671_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 9.941e-210 656.0
HFD2_k127_3751671_1 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 460.0
HFD2_k127_3751671_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 426.0
HFD2_k127_3751671_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009889 280.0
HFD2_k127_3751671_4 PFAM type IV pilus assembly PilZ - - - 0.00000000000000000000000000000000000000000000001536 174.0
HFD2_k127_3751671_5 CoA binding domain K06929 - - 0.0000000000000000000000000000001292 128.0
HFD2_k127_3751671_6 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000001614 76.0
HFD2_k127_3751671_8 response regulator - - - 0.0000000005256 64.0
HFD2_k127_3774510_0 Domain of unknown function (DUF4331) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 539.0
HFD2_k127_3774510_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 376.0
HFD2_k127_3774510_2 Angiotensin-converting enzyme K01283 - 3.4.15.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 298.0
HFD2_k127_3774510_3 regulation of single-species biofilm formation K13572 - - 0.00001248 47.0
HFD2_k127_3778560_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.928e-302 945.0
HFD2_k127_3778560_1 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 2.95e-271 856.0
HFD2_k127_3778560_2 AMP-binding enzyme C-terminal domain K00666 - - 2.943e-238 750.0
HFD2_k127_3778560_3 Alpha/beta hydrolase family K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 463.0
HFD2_k127_3778560_4 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 325.0
HFD2_k127_3778560_5 Haem-degrading - - - 0.0000000000000000000000000000000000000000000000000000000000003366 213.0
HFD2_k127_3846857_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001129 301.0
HFD2_k127_3846857_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000004005 151.0
HFD2_k127_3855279_0 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 373.0
HFD2_k127_3855279_1 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000468 158.0
HFD2_k127_3855279_2 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.000000000000000000000000000000000003391 140.0
HFD2_k127_3855279_3 PFAM PilT protein domain protein - - - 0.0000000000000000000000000000001432 127.0
HFD2_k127_3855279_5 positive regulation of growth - - - 0.0000000000000009228 79.0
HFD2_k127_3872109_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 2.464e-238 743.0
HFD2_k127_3872109_1 Glycosyl-hydrolase 97 N-terminal K01187 - 3.2.1.20 3.705e-230 733.0
HFD2_k127_3872109_10 UPF0391 membrane protein - - - 0.0001075 47.0
HFD2_k127_3872109_2 L-lactate permease K03303 - - 1.663e-228 722.0
HFD2_k127_3872109_3 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 6.687e-224 714.0
HFD2_k127_3872109_4 cell redox homeostasis - - - 3.382e-211 675.0
HFD2_k127_3872109_5 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648 372.0
HFD2_k127_3872109_6 PFAM Thymidine kinase K00857 - 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 356.0
HFD2_k127_3872109_7 iron ion homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008888 251.0
HFD2_k127_3872109_8 DNA-binding transcription factor activity K02081,K02444 - - 0.00000000000000000000000000000000000000000000000000000000000000000004683 243.0
HFD2_k127_3872109_9 protocatechuate 3,4-dioxygenase activity - - - 0.0000000000000000000000000000003193 135.0
HFD2_k127_3887547_0 Major facilitator Superfamily - - - 5.547e-197 637.0
HFD2_k127_3887547_1 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 367.0
HFD2_k127_3887547_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 378.0
HFD2_k127_3887547_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000004081 166.0
HFD2_k127_3929340_0 FtsX-like permease family - - - 7.796e-262 834.0
HFD2_k127_3929340_1 PFAM Integrase catalytic - - - 1.464e-245 769.0
HFD2_k127_3929340_10 Helix-turn-helix domain - - - 0.000000000000000000000000000002491 125.0
HFD2_k127_3929340_11 metallopeptidase activity - - - 0.0000000000000000000000000006129 128.0
HFD2_k127_3929340_12 Dehydratase small subunit K06122,K13920 - 4.2.1.28,4.2.1.30 0.000000000000000000000019 103.0
HFD2_k127_3929340_13 DNA-dependent DNA replication K02315 - - 0.00000000000000000006786 95.0
HFD2_k127_3929340_14 DNA ligase N terminus K10747 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.0003237 50.0
HFD2_k127_3929340_16 PIN domain - - - 0.0009976 49.0
HFD2_k127_3929340_2 Dehydratase large subunit K01699,K06120 - 4.2.1.28,4.2.1.30 9.307e-219 701.0
HFD2_k127_3929340_3 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 401.0
HFD2_k127_3929340_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 406.0
HFD2_k127_3929340_5 IstB-like ATP binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001389 241.0
HFD2_k127_3929340_6 dehydratase medium subunit K13919 - 4.2.1.28 0.00000000000000000000000000000000000000000000001334 194.0
HFD2_k127_3929340_7 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000000000000002165 152.0
HFD2_k127_3929340_8 creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000004324 160.0
HFD2_k127_3929340_9 OsmC-like protein - - - 0.00000000000000000000000000000000004746 141.0
HFD2_k127_3932923_0 transport - - - 2.935e-312 1000.0
HFD2_k127_3932923_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 4.776e-256 794.0
HFD2_k127_3932923_10 BON domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000721 234.0
HFD2_k127_3932923_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000001782 190.0
HFD2_k127_3932923_13 - - - - 0.0000000000000000000000000000000000007781 147.0
HFD2_k127_3932923_14 sequence-specific DNA binding K15539 - - 0.00000000000000000000003724 116.0
HFD2_k127_3932923_16 - - - - 0.00000000000000003856 96.0
HFD2_k127_3932923_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 9.825e-194 608.0
HFD2_k127_3932923_3 FAD dependent oxidoreductase K00514 - 1.3.5.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 593.0
HFD2_k127_3932923_4 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 532.0
HFD2_k127_3932923_5 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 505.0
HFD2_k127_3932923_6 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 475.0
HFD2_k127_3932923_7 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 458.0
HFD2_k127_3932923_8 mannose-ethanolamine phosphotransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 438.0
HFD2_k127_3932923_9 Putative serine dehydratase domain K01753 - 4.3.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 415.0
HFD2_k127_3943992_0 TonB-dependent receptor - - - 1.232e-207 688.0
HFD2_k127_3943992_1 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 541.0
HFD2_k127_3943992_10 xyloglucan:xyloglucosyl transferase activity K07004 - - 0.00000000000000000000000003267 125.0
HFD2_k127_3943992_11 RESPONSE REGULATOR receiver - - - 0.000000000000000005691 91.0
HFD2_k127_3943992_12 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000006621 85.0
HFD2_k127_3943992_13 Putative zinc-finger - - - 0.00000000000002496 85.0
HFD2_k127_3943992_14 - - - - 0.000001136 59.0
HFD2_k127_3943992_15 Domain of unknown function (DUF4132) - - - 0.000009589 58.0
HFD2_k127_3943992_2 D-mannonate dehydratase (UxuA) K01686 - 4.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 431.0
HFD2_k127_3943992_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009964 387.0
HFD2_k127_3943992_4 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001035 276.0
HFD2_k127_3943992_5 PFAM chemotaxis sensory transducer K03406,K05874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001764 291.0
HFD2_k127_3943992_6 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000000000001888 187.0
HFD2_k127_3943992_7 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000006661 162.0
HFD2_k127_3943992_8 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000000000888 153.0
HFD2_k127_3943992_9 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000001027 140.0
HFD2_k127_3955971_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 3.776e-250 779.0
HFD2_k127_3955971_1 inositol 2-dehydrogenase activity - - - 2.811e-204 640.0
HFD2_k127_3955971_2 Peptidase M16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 443.0
HFD2_k127_3955971_3 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 366.0
HFD2_k127_3955971_4 PFAM glucosamine galactosamine-6-phosphate isomerase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 340.0
HFD2_k127_3955971_5 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K21310 - 2.1.1.334 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 333.0
HFD2_k127_3955971_6 Glucose-6-phosphate dehydrogenase subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007678 261.0
HFD2_k127_3955971_7 - - - - 0.000000000000000000000000000000000000000000000001112 176.0
HFD2_k127_3955971_9 PFAM Rieske 2Fe-2S K00363 - 1.7.1.15 0.000000000000000000000000000000004406 132.0
HFD2_k127_4063268_0 FAD dependent oxidoreductase - - - 4.027e-207 657.0
HFD2_k127_4063268_1 phosphoprotein phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 323.0
HFD2_k127_4063268_2 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.00000000000000000000000000000000000000000000000000000000001259 231.0
HFD2_k127_4063268_3 CsbD-like - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000904 56.0
HFD2_k127_4095146_0 peptidase activity, acting on L-amino acid peptides K20276,K21449 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000526 305.0
HFD2_k127_4095146_1 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000007492 168.0
HFD2_k127_4095146_2 - - - - 0.00000000000000000000000000000000000000002715 162.0
HFD2_k127_4167368_0 E-Z type HEAT repeats - - - 1.735e-289 926.0
HFD2_k127_4167368_1 amine dehydrogenase activity - - - 1.071e-221 703.0
HFD2_k127_4167368_10 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000002079 203.0
HFD2_k127_4167368_11 cyclic nucleotide binding K00384,K10914 - 1.8.1.9 0.00000000000000000000000000000000000000000001229 171.0
HFD2_k127_4167368_12 Cytochrome c - - - 0.0000000000000000000000000000000000000000001108 169.0
HFD2_k127_4167368_13 molybdenum cofactor guanylyltransferase activity K03637,K03752,K13818 - 2.7.7.77,4.6.1.17 0.00000000000000000000000000000000001305 142.0
HFD2_k127_4167368_14 Multidrug Resistance protein - - - 0.00000000000000000000000000000001015 131.0
HFD2_k127_4167368_15 Small Multidrug Resistance protein - - - 0.00000000000000000000000000000001847 137.0
HFD2_k127_4167368_16 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000000006341 111.0
HFD2_k127_4167368_17 PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K07443 - - 0.00000000000000000000001162 104.0
HFD2_k127_4167368_18 - - - - 0.00000000000000000000007556 102.0
HFD2_k127_4167368_2 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - 4.897e-215 677.0
HFD2_k127_4167368_20 Protein of unknown function (DUF433) - - - 0.000000000000000004404 90.0
HFD2_k127_4167368_21 Protein of unknown function (DUF1326) - - - 0.000000000000325 70.0
HFD2_k127_4167368_22 - - - - 0.00000000001743 69.0
HFD2_k127_4167368_23 nuclease activity K07062 - - 0.0000000003092 62.0
HFD2_k127_4167368_24 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000004965 54.0
HFD2_k127_4167368_25 nuclease activity K07062 - - 0.00000217 51.0
HFD2_k127_4167368_3 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 7.644e-197 623.0
HFD2_k127_4167368_4 PQQ-like domain K00114 - 1.1.2.8 5.647e-194 624.0
HFD2_k127_4167368_5 PFAM Nucleotidyl transferase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008292 481.0
HFD2_k127_4167368_6 pfam abc K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005069 427.0
HFD2_k127_4167368_7 signal peptide processing K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 406.0
HFD2_k127_4167368_8 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000384 278.0
HFD2_k127_4167368_9 cyclic nucleotide binding K00384,K10914 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000001014 229.0
HFD2_k127_4168175_0 Domain of unknown function (DUF1998) K06877 - - 0.0 1279.0
HFD2_k127_4168175_1 ABC transporter transmembrane K11085 - - 6.441e-253 796.0
HFD2_k127_4168175_10 KR domain K00059,K18337 - 1.1.1.100,1.1.1.173,1.1.1.377,1.1.1.378 0.00000000000000000000000000000000000000000000000000000000000000000000000008292 256.0
HFD2_k127_4168175_11 CarD-like/TRCF domain K07736 - - 0.000000000000000000000000000000000000000000000000000000000000000000021 236.0
HFD2_k127_4168175_12 - - - - 0.0000000000000000000000000000000000000000000000000000000008593 201.0
HFD2_k127_4168175_13 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000005985 203.0
HFD2_k127_4168175_14 Yip1 domain - - - 0.000000000000000000000000000000000000000000104 166.0
HFD2_k127_4168175_15 L-rhamnose mutarotase - - - 0.0000000000000000000000000000000000000000014 161.0
HFD2_k127_4168175_16 Periplasmic or secreted lipoprotein - - - 0.0000000000000000000000000000000000001571 150.0
HFD2_k127_4168175_19 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000001086 123.0
HFD2_k127_4168175_2 Converts the aldose L-fucose into the corresponding ketose L-fuculose K01804 - 5.3.1.4 2.404e-195 621.0
HFD2_k127_4168175_21 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.000000000000001569 78.0
HFD2_k127_4168175_22 ATP-dependent DNA helicase activity K01144,K16898 - 3.1.11.5,3.6.4.12 0.00000000000003256 73.0
HFD2_k127_4168175_3 PFAM Xylose isomerase K01820 - 5.3.1.14 1.182e-194 617.0
HFD2_k127_4168175_4 Psort location Cytoplasmic, score 7.50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 571.0
HFD2_k127_4168175_5 carboxylic acid catabolic process K01684 - 4.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 437.0
HFD2_k127_4168175_6 beta-N-acetylhexosaminidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 436.0
HFD2_k127_4168175_7 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 382.0
HFD2_k127_4168175_8 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007512 344.0
HFD2_k127_4168175_9 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005942 312.0
HFD2_k127_4183916_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 382.0
HFD2_k127_4183916_1 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 367.0
HFD2_k127_4183916_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004904 262.0
HFD2_k127_4186234_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 5.182e-313 985.0
HFD2_k127_4186234_1 Flotillin K07192 - - 3.636e-224 703.0
HFD2_k127_4186234_2 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 483.0
HFD2_k127_4186234_3 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 381.0
HFD2_k127_4186234_4 choline dehydrogenase activity K03333 - 1.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 345.0
HFD2_k127_4186234_5 PFAM peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001862 269.0
HFD2_k127_4186234_6 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000125 265.0
HFD2_k127_4186234_7 Membrane protein implicated in regulation of membrane protease activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004478 268.0
HFD2_k127_4186234_8 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002145 258.0
HFD2_k127_4204123_0 Peptidase M56 - - - 1.62e-279 867.0
HFD2_k127_4204123_1 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 2.317e-247 767.0
HFD2_k127_4204123_10 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 295.0
HFD2_k127_4204123_11 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002486 277.0
HFD2_k127_4204123_12 carboxylic acid catabolic process K01684 - 4.2.1.6 0.0000000000000000000000000000000000000000008463 162.0
HFD2_k127_4204123_13 mRNA cleavage K19158 - - 0.00000000000000000000000000000000000000001423 155.0
HFD2_k127_4204123_14 toxin-antitoxin pair type II binding K08591,K19159 - 2.3.1.15 0.0000000000000000000000000000000001373 139.0
HFD2_k127_4204123_2 Carboxypeptidase regulatory-like domain - - - 9.639e-228 720.0
HFD2_k127_4204123_3 AAA ATPase K07478 - - 1.3e-214 674.0
HFD2_k127_4204123_4 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 551.0
HFD2_k127_4204123_5 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006703 491.0
HFD2_k127_4204123_6 Zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 421.0
HFD2_k127_4204123_7 Response regulator receiver K07705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 398.0
HFD2_k127_4204123_8 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 425.0
HFD2_k127_4204123_9 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006468 301.0
HFD2_k127_4246595_0 Arginosuccinate synthase K01940 - 6.3.4.5 9.946e-220 685.0
HFD2_k127_4246595_1 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 5.238e-208 652.0
HFD2_k127_4246595_10 PFAM von Willebrand factor type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 405.0
HFD2_k127_4246595_11 Belongs to the tRNA nucleotidyltransferase poly(A) polymerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 355.0
HFD2_k127_4246595_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 342.0
HFD2_k127_4246595_13 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 316.0
HFD2_k127_4246595_14 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005431 314.0
HFD2_k127_4246595_15 Transporter, CPA2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000001731 246.0
HFD2_k127_4246595_16 Regulates arginine biosynthesis genes K03402 - - 0.00000000000000000000000000000000000000000000000000001035 205.0
HFD2_k127_4246595_17 - - - - 0.0000000000000000000000000000000000000000000000000004861 190.0
HFD2_k127_4246595_18 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.00000000000000000000000000000001499 129.0
HFD2_k127_4246595_19 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000004479 79.0
HFD2_k127_4246595_2 argininosuccinate lyase K01755 - 4.3.2.1 7.294e-204 654.0
HFD2_k127_4246595_3 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 602.0
HFD2_k127_4246595_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 563.0
HFD2_k127_4246595_5 BNR repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 560.0
HFD2_k127_4246595_6 Coenzyme A transferase K01026 - 2.8.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006439 478.0
HFD2_k127_4246595_7 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 461.0
HFD2_k127_4246595_8 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 448.0
HFD2_k127_4246595_9 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 428.0
HFD2_k127_4266588_0 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.0 1077.0
HFD2_k127_4266588_1 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004587 260.0
HFD2_k127_4303258_0 arylsulfatase activity - - - 1.132e-228 716.0
HFD2_k127_4303258_1 Amino acid permease K03294 - - 7.2e-224 702.0
HFD2_k127_4303258_10 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009695 316.0
HFD2_k127_4303258_11 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000002072 236.0
HFD2_k127_4303258_12 heme binding K21472 - - 0.000000000000000000000000000000000000000000000000000000004962 206.0
HFD2_k127_4303258_13 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000001894 190.0
HFD2_k127_4303258_2 Protein of unknown function (DUF1549) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 603.0
HFD2_k127_4303258_3 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 496.0
HFD2_k127_4303258_4 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 475.0
HFD2_k127_4303258_5 synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 445.0
HFD2_k127_4303258_6 PQQ-like domain K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 412.0
HFD2_k127_4303258_7 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 394.0
HFD2_k127_4303258_8 Peptidoglycan-binding domain 1 protein K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 395.0
HFD2_k127_4303258_9 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 303.0
HFD2_k127_4324899_0 Signal transduction histidine kinase - - - 3.86e-205 658.0
HFD2_k127_4324899_1 domain protein - - - 2.097e-198 640.0
HFD2_k127_4324899_2 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 471.0
HFD2_k127_4324899_3 PFAM peptidase M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004242 440.0
HFD2_k127_4324899_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001475 246.0
HFD2_k127_4324899_5 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000001279 201.0
HFD2_k127_4341699_0 Glycosyl hydrolase family 20, domain 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009886 600.0
HFD2_k127_4341699_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 494.0
HFD2_k127_4341699_2 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 419.0
HFD2_k127_4341699_3 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000004468 237.0
HFD2_k127_4358118_0 Carboxypeptidase regulatory-like domain - - - 0.0 1498.0
HFD2_k127_4358118_1 peptidyl-tyrosine sulfation - - - 0.0 1052.0
HFD2_k127_4358118_2 peptidyl-tyrosine sulfation - - - 8.017e-212 671.0
HFD2_k127_4358118_3 GMC oxidoreductase - - - 1.195e-199 628.0
HFD2_k127_4358118_4 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 431.0
HFD2_k127_4358118_6 PFAM secretion protein HlyD family protein K02005,K02022 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 300.0
HFD2_k127_4358118_7 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K19715 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0043170,GO:0044238,GO:0071704,GO:1901576 2.6.1.109 0.000000000000000000000000000000000000000000000000000000000000000000000000000000393 289.0
HFD2_k127_4358118_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000003704 175.0
HFD2_k127_4358118_9 Elongation factor SelB, winged helix K03833 - - 0.00000000000007345 72.0
HFD2_k127_4366922_0 Protein of unknown function, DUF255 K06888 - - 8.203e-315 977.0
HFD2_k127_4366922_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.585e-263 816.0
HFD2_k127_4366922_10 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 398.0
HFD2_k127_4366922_11 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006107 386.0
HFD2_k127_4366922_12 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000047 362.0
HFD2_k127_4366922_13 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005088 363.0
HFD2_k127_4366922_14 pyrroloquinoline quinone binding K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007146 320.0
HFD2_k127_4366922_15 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007026 311.0
HFD2_k127_4366922_16 ABC transporter K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 307.0
HFD2_k127_4366922_17 Redoxin K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 281.0
HFD2_k127_4366922_18 Cobalt transport protein K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000001809 237.0
HFD2_k127_4366922_19 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000000000005321 200.0
HFD2_k127_4366922_2 peptidase dimerisation domain - - - 1.477e-237 742.0
HFD2_k127_4366922_20 - - - - 0.000000000000000000000000000000001181 134.0
HFD2_k127_4366922_21 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.00000000000000000000000002852 120.0
HFD2_k127_4366922_22 PFAM type IV pilus assembly PilZ - - - 0.000000000000000000002058 98.0
HFD2_k127_4366922_23 Stress responsive A/B Barrel Domain - - - 0.000000000000000000002228 98.0
HFD2_k127_4366922_25 phosphorelay signal transduction system - - - 0.00002035 53.0
HFD2_k127_4366922_26 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.00006612 46.0
HFD2_k127_4366922_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009359 582.0
HFD2_k127_4366922_4 Fumarase C C-terminus K01679 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 573.0
HFD2_k127_4366922_5 carboxylic acid catabolic process K01684 - 4.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 551.0
HFD2_k127_4366922_6 peptidoglycan biosynthetic process K21004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 545.0
HFD2_k127_4366922_7 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 537.0
HFD2_k127_4366922_8 mevalonate kinase activity K00869,K00938,K16190 - 2.7.1.36,2.7.1.43,2.7.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 521.0
HFD2_k127_4366922_9 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 435.0
HFD2_k127_4367401_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 395.0
HFD2_k127_4367401_2 Belongs to the peptidase S8 family K01342,K14645 - 3.4.21.62 0.000000000000000000000000000000000000000000000000000001002 196.0
HFD2_k127_4367401_3 Surface antigen - - - 0.00000000000000000004435 104.0
HFD2_k127_4367401_4 - - - - 0.0000000000000000001528 90.0
HFD2_k127_4376446_0 phosphorelay signal transduction system K07712,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 468.0
HFD2_k127_4376446_1 protein histidine kinase activity K03407,K07678 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007471 330.0
HFD2_k127_4376446_2 type II secretion system K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009937 319.0
HFD2_k127_4376446_3 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000001589 218.0
HFD2_k127_4376446_4 Response regulator, receiver K11443 - - 0.000000000000000000000005264 116.0
HFD2_k127_4376446_5 photoreceptor activity K08481 - - 0.0008326 44.0
HFD2_k127_4377981_0 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009263 511.0
HFD2_k127_4377981_1 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000008387 167.0
HFD2_k127_4377981_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000002106 119.0
HFD2_k127_4392240_0 Pilus assembly protein K02461,K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 460.0
HFD2_k127_4392240_4 general secretion pathway protein K02456,K02458,K02459,K10927 - - 0.00000000000000000000000000000000000000000003892 167.0
HFD2_k127_4450886_1 COG3119 Arylsulfatase A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004614 408.0
HFD2_k127_4450886_2 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 383.0
HFD2_k127_4450886_3 CBD_II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 331.0
HFD2_k127_4450886_4 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 310.0
HFD2_k127_4450886_5 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000003101 269.0
HFD2_k127_4450886_6 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000005366 228.0
HFD2_k127_4450886_7 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000003324 193.0
HFD2_k127_4450886_8 NIPSNAP family containing protein - - - 0.000000000000000000000000000000000004008 144.0
HFD2_k127_4450886_9 Leucine-rich repeats, outliers - - - 0.00000000000000000001785 103.0
HFD2_k127_4451133_0 Putative glutamine amidotransferase - - - 2.568e-317 990.0
HFD2_k127_4451133_1 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 370.0
HFD2_k127_4451133_2 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001458 277.0
HFD2_k127_4451133_3 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000002166 144.0
HFD2_k127_4451133_5 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides - - - 0.0001301 52.0
HFD2_k127_4462652_0 DegT/DnrJ/EryC1/StrS aminotransferase family K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000781 500.0
HFD2_k127_4462652_1 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 456.0
HFD2_k127_4462652_2 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000004268 237.0
HFD2_k127_4462652_3 Sugar transferase - - - 0.000000000000000000000000000000000000000000000000000001292 204.0
HFD2_k127_4462652_4 -O-antigen K02847 - - 0.000000000000000000000000000000000000008864 154.0
HFD2_k127_4462652_5 FR47-like protein - - - 0.0000000008212 70.0
HFD2_k127_4468496_0 efflux transmembrane transporter activity K02004 - - 5.494e-217 683.0
HFD2_k127_4468496_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 301.0
HFD2_k127_4468496_2 PFAM secretion protein HlyD family protein K02005,K02022 - - 0.000000000000000000000000000000000000000004059 165.0
HFD2_k127_4503214_0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 418.0
HFD2_k127_4503214_1 4-phosphoerythronate dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008019 395.0
HFD2_k127_4503214_2 - - - - 0.0000000117 63.0
HFD2_k127_45326_0 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 424.0
HFD2_k127_45326_1 - - - - 0.0000000000000000000000000000000000000000000000001338 181.0
HFD2_k127_45326_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000006986 149.0
HFD2_k127_4555905_0 phosphopantetheine binding - - - 7.594e-241 761.0
HFD2_k127_4555905_1 Methyltransferase domain - - - 6.389e-213 674.0
HFD2_k127_4555905_10 Methyltransferase domain - - - 0.000000000000001277 81.0
HFD2_k127_4555905_11 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000002703 78.0
HFD2_k127_4555905_12 positive regulation of growth K18829 - - 0.0000000001062 64.0
HFD2_k127_4555905_13 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000005854 55.0
HFD2_k127_4555905_15 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0001147 45.0
HFD2_k127_4555905_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 376.0
HFD2_k127_4555905_3 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003052 279.0
HFD2_k127_4555905_4 protein conserved in cyanobacteria - - - 0.00000000000000000000000000000000000000008221 157.0
HFD2_k127_4555905_5 PIN domain - - - 0.00000000000000000000000000000000000002642 148.0
HFD2_k127_4555905_6 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000002358 133.0
HFD2_k127_4555905_7 PIN domain - - - 0.0000000000000000000000000000005983 129.0
HFD2_k127_4555905_8 CopG antitoxin of type II toxin-antitoxin system - - - 0.000000000000000000000000292 109.0
HFD2_k127_4555905_9 addiction module antidote protein HigA K21498 - - 0.0000000000000007555 79.0
HFD2_k127_455784_0 Pilus assembly protein K02461,K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 477.0
HFD2_k127_455784_1 protein secretion K02460 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006919 269.0
HFD2_k127_456869_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.0 1220.0
HFD2_k127_456869_1 4Fe-4S dicluster domain - - - 1.834e-298 925.0
HFD2_k127_456869_10 FRG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 386.0
HFD2_k127_456869_11 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 383.0
HFD2_k127_456869_12 sequence-specific DNA binding K01239,K02855,K07506,K18199 - 3.2.2.1,4.2.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 330.0
HFD2_k127_456869_13 xanthine dehydrogenase activity K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 317.0
HFD2_k127_456869_14 2 iron, 2 sulfur cluster binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000009389 270.0
HFD2_k127_456869_15 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005532 267.0
HFD2_k127_456869_16 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000006542 230.0
HFD2_k127_456869_17 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000000000000000000007918 184.0
HFD2_k127_456869_18 - - - - 0.00000000000000000000000000000000000000000000000007637 183.0
HFD2_k127_456869_19 oxidoreductase activity, acting on CH-OH group of donors K09386 - - 0.00000000000000000000000000000000000000000000004522 181.0
HFD2_k127_456869_2 Evidence 4 Homologs of previously reported genes of - - - 3.564e-244 759.0
HFD2_k127_456869_20 Putative stress-induced transcription regulator - - - 0.000000000000000000000000000000000000000000001974 171.0
HFD2_k127_456869_21 TPR repeat - - - 0.0000000000000000000000000000000000000000514 162.0
HFD2_k127_456869_22 RNA recognition motif - - - 0.000000000000000000000000000000000003223 139.0
HFD2_k127_456869_26 - - - - 0.00003317 47.0
HFD2_k127_456869_3 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 4.167e-213 679.0
HFD2_k127_456869_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 575.0
HFD2_k127_456869_5 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 533.0
HFD2_k127_456869_6 PFAM NAD-dependent epimerase dehydratase K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 527.0
HFD2_k127_456869_7 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009623 523.0
HFD2_k127_456869_9 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 504.0
HFD2_k127_4595939_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 8.264e-277 855.0
HFD2_k127_4595939_1 Carboxypeptidase regulatory-like domain - - - 1.211e-275 887.0
HFD2_k127_4595939_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 7.719e-273 847.0
HFD2_k127_4595939_3 Prokaryotic cytochrome b561 - - - 2.639e-271 855.0
HFD2_k127_4595939_4 Prokaryotic cytochrome b561 - - - 9.541e-196 624.0
HFD2_k127_4595939_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000002725 250.0
HFD2_k127_4595939_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000000002396 211.0
HFD2_k127_4595939_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000981 167.0
HFD2_k127_4595939_8 ATP synthase, Delta/Epsilon chain, beta-sandwich domain K02114 - - 0.0000000000000000000000000000000000000002281 157.0
HFD2_k127_4600880_0 TIGRFAM ATP-dependent DNA helicase, RecQ family K03169,K03654 - 3.6.4.12,5.99.1.2 0.0 1846.0
HFD2_k127_4600880_1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01585 - 4.1.1.19 0.0 1118.0
HFD2_k127_4600880_10 COG2706 3-carboxymuconate cyclase K07404 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005133 417.0
HFD2_k127_4600880_11 Fumarylacetoacetate (FAA) hydrolase family K14259 - 4.2.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007144 370.0
HFD2_k127_4600880_12 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 343.0
HFD2_k127_4600880_13 nucleotidyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 316.0
HFD2_k127_4600880_14 PFAM LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001832 260.0
HFD2_k127_4600880_15 Modulates RecA activity K03565 - - 0.00000000000000000000000000000000000000000000000000000002596 209.0
HFD2_k127_4600880_16 Ferredoxin - - - 0.00000000000000000000000000000000000000000002515 175.0
HFD2_k127_4600880_17 Met-10+ like-protein - - - 0.0000000000000000000000000000000000000000002961 166.0
HFD2_k127_4600880_18 YtxH-like protein - - - 0.00000000000000000000000000006312 119.0
HFD2_k127_4600880_2 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0 1052.0
HFD2_k127_4600880_20 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000001144 111.0
HFD2_k127_4600880_21 TPM domain K06872 - - 0.00000000000335 67.0
HFD2_k127_4600880_22 FAD dependent oxidoreductase - - - 0.000703 51.0
HFD2_k127_4600880_3 Belongs to the aldehyde dehydrogenase family K00141,K22187 - 1.2.1.28 9.384e-259 807.0
HFD2_k127_4600880_4 Carboxypeptidase regulatory-like domain - - - 1.642e-205 649.0
HFD2_k127_4600880_5 MlrC C-terminus - - - 5.976e-200 635.0
HFD2_k127_4600880_6 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005827 622.0
HFD2_k127_4600880_7 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000758 585.0
HFD2_k127_4600880_8 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 576.0
HFD2_k127_4600880_9 COG3119 Arylsulfatase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 449.0
HFD2_k127_461518_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 625.0
HFD2_k127_461518_1 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 450.0
HFD2_k127_461518_2 - - - - 0.00000000000000000000000000000001014 132.0
HFD2_k127_4682751_0 TonB-dependent receptor - - - 0.0 1368.0
HFD2_k127_4682751_1 Elongation factor SelB, winged helix K03833 - - 6.991e-246 781.0
HFD2_k127_4682751_2 inositol 2-dehydrogenase activity - - - 1.47e-231 723.0
HFD2_k127_4682751_3 Cytochrome c - - - 5.563e-213 683.0
HFD2_k127_4682751_4 long-chain fatty acid transporting porin activity - - - 1.912e-194 615.0
HFD2_k127_4682751_5 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 606.0
HFD2_k127_4682751_6 mandelate racemase muconate lactonizing K01684 - 4.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 309.0
HFD2_k127_4682751_7 VWA domain containing CoxE-like protein - - - 0.0000000000000000000000000003833 126.0
HFD2_k127_4685342_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1362.0
HFD2_k127_4685342_1 SMART serine threonine protein kinase - - - 6.133e-197 663.0
HFD2_k127_4685342_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 557.0
HFD2_k127_4685342_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001771 291.0
HFD2_k127_4685342_4 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000001613 243.0
HFD2_k127_4685342_5 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000001162 192.0
HFD2_k127_4751505_0 Lactonase, 7-bladed beta-propeller - - - 0.0 1141.0
HFD2_k127_4751505_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0 1123.0
HFD2_k127_4751505_10 TIGRFAM type VI secretion system Vgr family protein K11904 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 468.0
HFD2_k127_4751505_11 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 434.0
HFD2_k127_4751505_12 mandelate racemase muconate lactonizing K01684,K01781,K08323 - 4.2.1.6,4.2.1.8,5.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 441.0
HFD2_k127_4751505_13 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 354.0
HFD2_k127_4751505_14 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 323.0
HFD2_k127_4751505_15 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009327 309.0
HFD2_k127_4751505_16 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 290.0
HFD2_k127_4751505_17 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 298.0
HFD2_k127_4751505_19 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 297.0
HFD2_k127_4751505_2 Glycosyl hydrolase family 57 - - - 4.424e-306 960.0
HFD2_k127_4751505_20 Peptidoglycan-binding domain 1 protein K01447,K07126,K13582 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000002552 211.0
HFD2_k127_4751505_21 acetyltransferase - - - 0.000000000000000000000000000000000000000000221 174.0
HFD2_k127_4751505_22 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000001005 151.0
HFD2_k127_4751505_23 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000001022 138.0
HFD2_k127_4751505_24 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000005305 117.0
HFD2_k127_4751505_25 Calcineurin-like phosphoesterase - - - 0.0000000000000000000002565 114.0
HFD2_k127_4751505_26 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0071944 - 0.000000000005175 69.0
HFD2_k127_4751505_28 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.0000000001461 66.0
HFD2_k127_4751505_3 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 5.12e-266 841.0
HFD2_k127_4751505_30 PAAR motif - - - 0.00000001525 60.0
HFD2_k127_4751505_4 amino acid K03294 - - 8.673e-257 799.0
HFD2_k127_4751505_5 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.044e-233 728.0
HFD2_k127_4751505_6 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 7.662e-220 694.0
HFD2_k127_4751505_8 alpha beta - - - 3.154e-197 640.0
HFD2_k127_4751505_9 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 563.0
HFD2_k127_4764219_0 Carboxypeptidase regulatory-like domain - - - 5.503e-226 718.0
HFD2_k127_4765689_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.749e-273 846.0
HFD2_k127_4765689_1 phosphoglucosamine mutase activity K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 1.845e-221 702.0
HFD2_k127_4765689_10 metal cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000007877 214.0
HFD2_k127_4765689_11 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000006817 182.0
HFD2_k127_4765689_12 pyrroloquinoline quinone binding K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000005874 187.0
HFD2_k127_4765689_13 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000000000000000000002943 183.0
HFD2_k127_4765689_14 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.00000000000000000000000000000000000000001638 155.0
HFD2_k127_4765689_15 helix_turn_helix, Lux Regulon - - - 0.00000000522 61.0
HFD2_k127_4765689_16 Psort location CytoplasmicMembrane, score - - - 0.0002943 51.0
HFD2_k127_4765689_2 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 440.0
HFD2_k127_4765689_3 Iron-containing alcohol dehydrogenase K00001,K01714,K13954 - 1.1.1.1,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 415.0
HFD2_k127_4765689_4 Pfam Adenylate and Guanylate cyclase catalytic domain K01768,K07169,K11894 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 343.0
HFD2_k127_4765689_5 Uroporphyrinogen decarboxylase (URO-D) K01599,K14080 - 2.1.1.246,4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006563 311.0
HFD2_k127_4765689_6 PFAM Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008983 293.0
HFD2_k127_4765689_7 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003357 275.0
HFD2_k127_4765689_8 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000002 267.0
HFD2_k127_4765689_9 methionine synthase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000004591 223.0
HFD2_k127_4807512_0 - - - - 0.0000000000000000000000000269 113.0
HFD2_k127_4807512_1 - - - - 0.00000003586 64.0
HFD2_k127_4862823_0 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnJ - - - 1.477e-274 852.0
HFD2_k127_4862823_1 membrane - - - 0.000000000000000000000000000000000000000003699 159.0
HFD2_k127_4862823_2 EamA-like transporter family - - - 0.00000000000000000000000000000001475 130.0
HFD2_k127_4862823_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000659 102.0
HFD2_k127_4866926_0 amino acid - - - 0.0 1164.0
HFD2_k127_4866926_1 Protein of unknown function (DUF1343) - - - 0.0 1084.0
HFD2_k127_4866926_10 Belongs to the glycosyl hydrolase 32 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 460.0
HFD2_k127_4866926_11 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 389.0
HFD2_k127_4866926_12 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 347.0
HFD2_k127_4866926_13 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002922 250.0
HFD2_k127_4866926_14 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000346 211.0
HFD2_k127_4866926_15 cdp-diacylglycerol pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000007613 210.0
HFD2_k127_4866926_16 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000005591 189.0
HFD2_k127_4866926_17 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000008215 183.0
HFD2_k127_4866926_18 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000001007 176.0
HFD2_k127_4866926_19 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000003001 168.0
HFD2_k127_4866926_2 PA domain - - - 1.034e-259 815.0
HFD2_k127_4866926_20 - - - - 0.000000000000000000000000000000000000000005974 160.0
HFD2_k127_4866926_21 cell redox homeostasis - - - 0.000000000000000000000000000000000000009804 154.0
HFD2_k127_4866926_22 Inositol monophosphatase family - - - 0.0000000000000000000000000000000000007295 145.0
HFD2_k127_4866926_23 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000113 128.0
HFD2_k127_4866926_24 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000007315 90.0
HFD2_k127_4866926_27 - - - - 0.000002343 51.0
HFD2_k127_4866926_28 DinB family - - - 0.00003004 54.0
HFD2_k127_4866926_3 D-galactarate dehydratase / Altronate hydrolase, C terminus K01685 - 4.2.1.7 3.251e-240 751.0
HFD2_k127_4866926_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 7.646e-239 745.0
HFD2_k127_4866926_5 efflux transmembrane transporter activity - - - 1.063e-238 762.0
HFD2_k127_4866926_6 binding domain, Protein - - - 7.053e-207 651.0
HFD2_k127_4866926_7 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 6.677e-205 643.0
HFD2_k127_4866926_8 O-antigen ligase like membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000098 505.0
HFD2_k127_4866926_9 PFAM molybdopterin dehydrogenase, FAD-binding K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 452.0
HFD2_k127_4899152_0 TIGRFAM geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000000000000001848 200.0
HFD2_k127_4899152_1 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000002313 160.0
HFD2_k127_4910404_0 Amidohydrolase K10220,K14333 - 4.1.1.46,4.2.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 528.0
HFD2_k127_4910404_1 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 511.0
HFD2_k127_4910404_2 thiolester hydrolase activity - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000003245 129.0
HFD2_k127_4910404_3 lactoylglutathione lyase activity - - - 0.0000000008884 59.0
HFD2_k127_4917018_0 4-amino-4-deoxy-L-arabinose transferase activity K16648 - - 9.48e-216 692.0
HFD2_k127_4917018_1 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 369.0
HFD2_k127_4946381_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005773 523.0
HFD2_k127_4946381_1 beta-galactosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000008463 238.0
HFD2_k127_4946381_2 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000007973 146.0
HFD2_k127_4946381_3 Glucose inhibited division protein A - - - 0.00007066 46.0
HFD2_k127_4947039_0 D-galactarate dehydratase / Altronate hydrolase, C terminus K01708 - 4.2.1.42 9.117e-245 771.0
HFD2_k127_4947039_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008567 479.0
HFD2_k127_4947039_2 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 346.0
HFD2_k127_4947039_3 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 319.0
HFD2_k127_4947039_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 301.0
HFD2_k127_4947039_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000309 274.0
HFD2_k127_4947039_6 -acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000001375 203.0
HFD2_k127_4947039_7 Cell wall-active antibiotics response 4TMS YvqF - - - 0.000000000000000000000000000000000000000000007881 172.0
HFD2_k127_4947039_8 - - - - 0.0002483 50.0
HFD2_k127_496050_0 Belongs to the DegT DnrJ EryC1 family K19715 - 2.6.1.109 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 381.0
HFD2_k127_496050_1 IclR helix-turn-helix domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 314.0
HFD2_k127_4965091_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 8.601e-289 902.0
HFD2_k127_4965091_1 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 322.0
HFD2_k127_4965091_10 PFAM heat shock protein DnaJ domain protein K05516 - - 0.000000000269 71.0
HFD2_k127_4965091_2 extracellular polysaccharide biosynthetic process K08252,K13661,K16554 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 298.0
HFD2_k127_4965091_3 PFAM Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006673 263.0
HFD2_k127_4965091_4 4Fe-4S binding domain K04014,K08353,K08358,K16293 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044464,GO:0055114,GO:0098809 - 0.00000000000000000000000000000000000000000000000000000000000000000002501 237.0
HFD2_k127_4965091_5 - K07112 - - 0.000000000000000000000000000000000000000001339 166.0
HFD2_k127_4965091_6 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K07112 - - 0.00000000000000000000000000000000000000000136 174.0
HFD2_k127_4965091_7 -O-antigen K02847 - - 0.00000000000000000000000000000000000000002024 170.0
HFD2_k127_4965091_8 lipopolysaccharide metabolic process K08309,K19804 - - 0.0000000000000000000000000013 129.0
HFD2_k127_503466_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 1.139e-242 755.0
HFD2_k127_503466_1 cystathionine gamma-synthase activity K01739,K01740,K01760,K01761,K10764 - 2.5.1.48,2.5.1.49,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004361 606.0
HFD2_k127_503466_2 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 511.0
HFD2_k127_503466_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 482.0
HFD2_k127_503466_4 Pfam:DUF162 K00782 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007281 244.0
HFD2_k127_503466_5 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000001444 205.0
HFD2_k127_503466_6 cluster binding protein K18929 - - 0.00000000000000000000000001222 110.0
HFD2_k127_5085828_0 Ribosomal protein S1 K02945 - - 4.131e-310 956.0
HFD2_k127_5085828_1 intracellular protein transport - - - 4.501e-250 800.0
HFD2_k127_5085828_10 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000000000009956 212.0
HFD2_k127_5085828_11 - - - - 0.0000000000000000000000000000000000000000000000000000027 194.0
HFD2_k127_5085828_13 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000000000000000000000000005428 173.0
HFD2_k127_5085828_14 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000001266 174.0
HFD2_k127_5085828_17 - - - - 0.00000000000000000000000000000000009567 136.0
HFD2_k127_5085828_18 peroxiredoxin activity K03564 - 1.11.1.15 0.00000000000000000000000000000007583 126.0
HFD2_k127_5085828_19 TonB-dependent receptor - - - 0.00000000000000000000001184 102.0
HFD2_k127_5085828_2 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 455.0
HFD2_k127_5085828_20 peroxiredoxin activity K03564 - 1.11.1.15 0.000000000000000171 82.0
HFD2_k127_5085828_21 TonB-dependent receptor - - - 0.00000000000003768 75.0
HFD2_k127_5085828_22 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000001418 70.0
HFD2_k127_5085828_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 404.0
HFD2_k127_5085828_4 Belongs to the MIP aquaporin (TC 1.A.8) family K02440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 389.0
HFD2_k127_5085828_5 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001601 274.0
HFD2_k127_5085828_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000006995 238.0
HFD2_k127_5085828_7 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000001968 231.0
HFD2_k127_5085828_8 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000002814 217.0
HFD2_k127_5085828_9 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000003599 208.0
HFD2_k127_5086755_0 HD domain - - - 4.141e-253 805.0
HFD2_k127_5086755_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 1.252e-199 628.0
HFD2_k127_5086755_10 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 327.0
HFD2_k127_5086755_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009088 277.0
HFD2_k127_5086755_12 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006076 284.0
HFD2_k127_5086755_13 4Fe-4S binding domain K00395,K02572,K03616 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000007364 232.0
HFD2_k127_5086755_14 STAS domain K04749 - - 0.0000000000000000000000000000000000000000000000000000001628 196.0
HFD2_k127_5086755_15 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000005976 194.0
HFD2_k127_5086755_16 Redoxin - - - 0.0000000000000000000000000000000000000000000000006059 180.0
HFD2_k127_5086755_17 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000001797 100.0
HFD2_k127_5086755_18 metal-dependent protease of the Pad1 Jab1 superfamily - - - 0.000000000101 65.0
HFD2_k127_5086755_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 1.54e-197 621.0
HFD2_k127_5086755_3 Metalloenzyme superfamily K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007632 599.0
HFD2_k127_5086755_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 539.0
HFD2_k127_5086755_5 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007223 488.0
HFD2_k127_5086755_6 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 469.0
HFD2_k127_5086755_7 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 378.0
HFD2_k127_5086755_8 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 385.0
HFD2_k127_5086755_9 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 364.0
HFD2_k127_5088682_0 DNA topological change K03168 - 5.99.1.2 0.0 1128.0
HFD2_k127_5088682_1 Protein of unknown function (DUF1552) - - - 3.681e-216 681.0
HFD2_k127_5088682_2 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 390.0
HFD2_k127_5088682_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 362.0
HFD2_k127_5088682_4 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 302.0
HFD2_k127_5088682_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004898 274.0
HFD2_k127_5088682_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000001859 123.0
HFD2_k127_5088682_7 Psort location Periplasmic, score K09807 - - 0.0000000000000000000001692 106.0
HFD2_k127_5088682_8 Ankyrin repeat K06867 GO:0000122,GO:0000139,GO:0000976,GO:0000977,GO:0000978,GO:0000987,GO:0000988,GO:0000989,GO:0001012,GO:0001067,GO:0001076,GO:0001190,GO:0001568,GO:0001570,GO:0001666,GO:0001837,GO:0001932,GO:0001934,GO:0001944,GO:0001947,GO:0002009,GO:0002011,GO:0002193,GO:0002376,GO:0002682,GO:0002683,GO:0003007,GO:0003143,GO:0003151,GO:0003157,GO:0003158,GO:0003160,GO:0003169,GO:0003170,GO:0003171,GO:0003174,GO:0003176,GO:0003177,GO:0003179,GO:0003180,GO:0003181,GO:0003183,GO:0003184,GO:0003188,GO:0003190,GO:0003192,GO:0003197,GO:0003198,GO:0003203,GO:0003205,GO:0003206,GO:0003207,GO:0003208,GO:0003209,GO:0003213,GO:0003214,GO:0003222,GO:0003229,GO:0003230,GO:0003231,GO:0003241,GO:0003250,GO:0003252,GO:0003256,GO:0003272,GO:0003273,GO:0003279,GO:0003281,GO:0003330,GO:0003332,GO:0003344,GO:0003348,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005783,GO:0005789,GO:0005794,GO:0005829,GO:0005886,GO:0005912,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006357,GO:0006366,GO:0006367,GO:0006725,GO:0006807,GO:0006928,GO:0006950,GO:0006955,GO:0006996,GO:0007049,GO:0007050,GO:0007154,GO:0007162,GO:0007165,GO:0007166,GO:0007219,GO:0007221,GO:0007275,GO:0007368,GO:0007389,GO:0007399,GO:0007507,GO:0007517,GO:0008150,GO:0008152,GO:0008284,GO:0008285,GO:0008593,GO:0009058,GO:0009059,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009799,GO:0009855,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010002,GO:0010033,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010562,GO:0010594,GO:0010596,GO:0010604,GO:0010605,GO:0010611,GO:0010614,GO:0010628,GO:0010629,GO:0010632,GO:0010633,GO:0010646,GO:0010647,GO:0010648,GO:0010717,GO:0010718,GO:0010720,GO:0010721,GO:0010810,GO:0010812,GO:0010830,GO:0010832,GO:0010941,GO:0010942,GO:0012505,GO:0014013,GO:0014014,GO:0014015,GO:0014031,GO:0014706,GO:0014741,GO:0014743,GO:0016020,GO:0016043,GO:0016070,GO:0016202,GO:0016324,GO:0016477,GO:0016525,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019827,GO:0019899,GO:0022008,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030030,GO:0030031,GO:0030054,GO:0030154,GO:0030155,GO:0030234,GO:0030278,GO:0030279,GO:0030334,GO:0030335,GO:0030336,GO:0030510,GO:0030513,GO:0030514,GO:0030855,GO:0031090,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031399,GO:0031401,GO:0031974,GO:0031981,GO:0031984,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032354,GO:0032501,GO:0032502,GO:0032774,GO:0032870,GO:0032879,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0034698,GO:0035050,GO:0035051,GO:0035148,GO:0035239,GO:0035265,GO:0035295,GO:0035886,GO:0035924,GO:0036003,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0040009,GO:0040011,GO:0040012,GO:0040013,GO:0040017,GO:0042127,GO:0042175,GO:0042221,GO:0042325,GO:0042327,GO:0042692,GO:0042981,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043235,GO:0043408,GO:0043410,GO:0043502,GO:0043535,GO:0043537,GO:0043565,GO:0043618,GO:0043620,GO:0044057,GO:0044085,GO:0044087,GO:0044092,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044431,GO:0044432,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044782,GO:0045177,GO:0045445,GO:0045446,GO:0045595,GO:0045596,GO:0045597,GO:0045661,GO:0045662,GO:0045667,GO:0045668,GO:0045685,GO:0045686,GO:0045687,GO:0045747,GO:0045765,GO:0045786,GO:0045844,GO:0045892,GO:0045893,GO:0045926,GO:0045927,GO:0045934,GO:0045935,GO:0045937,GO:0045944,GO:0045967,GO:0046425,GO:0046427,GO:0046483,GO:0046578,GO:0046579,GO:0046620,GO:0046622,GO:0048468,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048585,GO:0048589,GO:0048598,GO:0048634,GO:0048636,GO:0048638,GO:0048639,GO:0048644,GO:0048646,GO:0048699,GO:0048710,GO:0048711,GO:0048713,GO:0048715,GO:0048729,GO:0048731,GO:0048738,GO:0048762,GO:0048844,GO:0048845,GO:0048856,GO:0048863,GO:0048869,GO:0048870,GO:0050767,GO:0050768,GO:0050769,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0050920,GO:0050922,GO:0051046,GO:0051048,GO:0051049,GO:0051051,GO:0051056,GO:0051057,GO:0051093,GO:0051094,GO:0051128,GO:0051129,GO:0051145,GO:0051147,GO:0051148,GO:0051153,GO:0051154,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051254,GO:0051270,GO:0051271,GO:0051272,GO:0051674,GO:0051716,GO:0051726,GO:0051960,GO:0051961,GO:0051962,GO:0055001,GO:0055006,GO:0055008,GO:0055010,GO:0055021,GO:0055023,GO:0055024,GO:0055025,GO:0060039,GO:0060043,GO:0060045,GO:0060251,GO:0060253,GO:0060255,GO:0060271,GO:0060284,GO:0060317,GO:0060379,GO:0060411,GO:0060412,GO:0060415,GO:0060419,GO:0060420,GO:0060421,GO:0060429,GO:0060485,GO:0060537,GO:0060548,GO:0060560,GO:0060562,GO:0060837,GO:0060840,GO:0060841,GO:0060842,GO:0060843,GO:0060947,GO:0060948,GO:0060956,GO:0060973,GO:0060976,GO:0060977,GO:0060979,GO:0060982,GO:0061061,GO:0061311,GO:0061314,GO:0061371,GO:0061383,GO:0061384,GO:0061418,GO:0061419,GO:0065007,GO:0065009,GO:0070013,GO:0070161,GO:0070167,GO:0070168,GO:0070372,GO:0070374,GO:0070482,GO:0070848,GO:0070887,GO:0070925,GO:0071310,GO:0071363,GO:0071371,GO:0071372,GO:0071453,GO:0071456,GO:0071495,GO:0071704,GO:0071840,GO:0071944,GO:0072132,GO:0072358,GO:0072359,GO:0080090,GO:0090049,GO:0090051,GO:0090092,GO:0090100,GO:0090101,GO:0090257,GO:0090287,GO:0090288,GO:0090304,GO:0097084,GO:0097150,GO:0097159,GO:0097659,GO:0098588,GO:0098590,GO:0098727,GO:0098772,GO:0098791,GO:0098827,GO:0120031,GO:0120036,GO:0140110,GO:1901201,GO:1901213,GO:1901342,GO:1901343,GO:1901360,GO:1901362,GO:1901363,GO:1901522,GO:1901532,GO:1901533,GO:1901576,GO:1901861,GO:1901863,GO:1902337,GO:1902339,GO:1902531,GO:1902533,GO:1902679,GO:1902680,GO:1903053,GO:1903054,GO:1903506,GO:1903507,GO:1903508,GO:1903530,GO:1903531,GO:1903670,GO:1903671,GO:1903706,GO:1903707,GO:1904747,GO:1904748,GO:1904892,GO:1904894,GO:1905314,GO:1905456,GO:1905457,GO:1990837,GO:2000026,GO:2000027,GO:2000112,GO:2000113,GO:2000136,GO:2000137,GO:2000145,GO:2000146,GO:2000147,GO:2000181,GO:2000209,GO:2000736,GO:2000737,GO:2000811,GO:2000826,GO:2000973,GO:2000974,GO:2001026,GO:2001027,GO:2001141 - 0.000000001797 66.0
HFD2_k127_5151278_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1031.0
HFD2_k127_5151278_1 Isocitrate/isopropylmalate dehydrogenase - - - 1.926e-230 723.0
HFD2_k127_5151278_10 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000008914 194.0
HFD2_k127_5151278_11 cheY-homologous receiver domain - - - 0.00000000000000000004802 97.0
HFD2_k127_5151278_12 cheY-homologous receiver domain - - - 0.0000002875 54.0
HFD2_k127_5151278_2 Peptidase family M28 - - - 1.719e-206 664.0
HFD2_k127_5151278_3 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 533.0
HFD2_k127_5151278_4 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 496.0
HFD2_k127_5151278_5 Hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 349.0
HFD2_k127_5151278_6 - K07018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006631 295.0
HFD2_k127_5151278_7 Oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006834 288.0
HFD2_k127_5151278_8 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001435 259.0
HFD2_k127_5151278_9 Kelch motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000003113 243.0
HFD2_k127_5158315_0 Cytochrome c - - - 3.504e-223 721.0
HFD2_k127_5158315_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 549.0
HFD2_k127_5241560_0 radical SAM domain protein K22318 - - 2.428e-265 828.0
HFD2_k127_5241560_1 Tetratricopeptide TPR_2 repeat protein - - - 1.356e-210 679.0
HFD2_k127_5241560_2 Alginate export - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 367.0
HFD2_k127_5241560_3 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008964 319.0
HFD2_k127_5241560_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000522 251.0
HFD2_k127_5248105_0 Protein of unknown function (DUF1595) - - - 1.002e-235 750.0
HFD2_k127_5248105_1 Protein of unknown function (DUF1552) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 590.0
HFD2_k127_5248105_2 exonuclease activity K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 331.0
HFD2_k127_5248105_3 Belongs to the HpcH HpaI aldolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 305.0
HFD2_k127_5248105_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 290.0
HFD2_k127_5248105_5 Selenocysteine lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000754 244.0
HFD2_k127_5248105_6 Selenocysteine lyase - - - 0.000000000000000000000000000000000000000000000000000000000000003184 233.0
HFD2_k127_5248105_7 Acetyltransferase (GNAT) domain K03789 GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 0.0000000002 67.0
HFD2_k127_525006_0 hydrolase, family 65, central catalytic K15923 - 3.2.1.51 0.0 1015.0
HFD2_k127_525006_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814,K05365 - 2.4.1.129,3.4.16.4 3.993e-259 846.0
HFD2_k127_525006_10 cyclic nucleotide binding K00384,K10914 - 1.8.1.9 0.000000000000000000000000000000000000000000000000006523 185.0
HFD2_k127_525006_11 Capsule assembly protein Wzi - - - 0.0000000000000000000000009693 115.0
HFD2_k127_525006_2 Sigma-54 interaction domain K02584,K07713,K15836,K21009 - - 4.679e-209 661.0
HFD2_k127_525006_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 516.0
HFD2_k127_525006_4 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006791 478.0
HFD2_k127_525006_5 SMART Tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 447.0
HFD2_k127_525006_6 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 297.0
HFD2_k127_525006_7 PFAM cyclase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000007939 240.0
HFD2_k127_525006_8 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000006802 231.0
HFD2_k127_525006_9 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000004944 213.0
HFD2_k127_5272281_0 Carboxypeptidase regulatory-like domain - - - 3.1e-322 1021.0
HFD2_k127_5272281_1 serine-type peptidase activity K06978,K21105 - 3.1.1.102 1.321e-232 739.0
HFD2_k127_5272281_10 PDZ DHR GLGF domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006808 250.0
HFD2_k127_5272281_11 PFAM dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000002041 220.0
HFD2_k127_5272281_12 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000235 191.0
HFD2_k127_5272281_13 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000002339 159.0
HFD2_k127_5272281_14 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family - - - 0.0000000000001209 78.0
HFD2_k127_5272281_2 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006721 509.0
HFD2_k127_5272281_3 MacB-like periplasmic core domain K02004,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 434.0
HFD2_k127_5272281_4 Peptidase S9 prolyl oligopeptidase active site domain protein K01303 - 3.4.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 432.0
HFD2_k127_5272281_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007024 354.0
HFD2_k127_5272281_6 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 329.0
HFD2_k127_5272281_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 310.0
HFD2_k127_5272281_8 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 294.0
HFD2_k127_5272281_9 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001695 283.0
HFD2_k127_5275096_0 transport - - - 3.732e-289 924.0
HFD2_k127_5275096_1 Beta-lactamase - - - 6.832e-251 797.0
HFD2_k127_5275096_10 recA bacterial DNA recombination protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005396 258.0
HFD2_k127_5275096_11 YceI-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001637 248.0
HFD2_k127_5275096_12 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000002657 198.0
HFD2_k127_5275096_13 Phytase K01083 - 3.1.3.8 0.000000000000000000000000000000000000000000000002012 179.0
HFD2_k127_5275096_14 Xylose isomerase-like TIM barrel K22233 - - 0.0000000000000000000000000000000000000000000005475 184.0
HFD2_k127_5275096_15 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000001334 146.0
HFD2_k127_5275096_16 - - - - 0.0000000000000000000000000000006591 127.0
HFD2_k127_5275096_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 1.057e-228 754.0
HFD2_k127_5275096_3 alcohol dehydrogenase K22231 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 555.0
HFD2_k127_5275096_4 Pirin C-terminal cupin domain K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 544.0
HFD2_k127_5275096_5 creatininase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009057 488.0
HFD2_k127_5275096_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 484.0
HFD2_k127_5275096_7 helix_turn _helix lactose operon repressor K05499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 430.0
HFD2_k127_5275096_8 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 398.0
HFD2_k127_5275096_9 Membrane-bound dehydrogenase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 381.0
HFD2_k127_5280439_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 2.219e-279 867.0
HFD2_k127_5280439_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.818e-251 788.0
HFD2_k127_5280439_11 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 396.0
HFD2_k127_5280439_12 multi-organism process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 320.0
HFD2_k127_5280439_13 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 296.0
HFD2_k127_5280439_14 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000009166 228.0
HFD2_k127_5280439_15 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000006979 190.0
HFD2_k127_5280439_16 general secretion pathway protein K02246,K02456,K02458 - - 0.00000000000000000000000000000000000000000000000001443 199.0
HFD2_k127_5280439_18 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000001411 169.0
HFD2_k127_5280439_2 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 1.18e-232 727.0
HFD2_k127_5280439_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.833e-228 716.0
HFD2_k127_5280439_4 4-amino-4-deoxy-L-arabinose transferase activity K16648 - - 1.201e-214 690.0
HFD2_k127_5280439_5 Type II secretion system (T2SS), protein F K02455 - - 1.548e-194 624.0
HFD2_k127_5280439_6 N-acetyldiaminopimelate deacetylase activity K12941 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 610.0
HFD2_k127_5280439_7 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 522.0
HFD2_k127_5280439_8 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 496.0
HFD2_k127_5280439_9 PFAM Major facilitator superfamily K08191 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 492.0
HFD2_k127_5292466_0 PFAM oxidoreductase domain protein - - - 3.282e-282 874.0
HFD2_k127_5292466_1 COG3119 Arylsulfatase A K01138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 475.0
HFD2_k127_5292466_2 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 321.0
HFD2_k127_5292466_3 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 296.0
HFD2_k127_5292466_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007052 294.0
HFD2_k127_5292466_6 DNA-templated transcription, initiation K03088 - - 0.00000001568 56.0
HFD2_k127_5328511_0 Amidohydrolase family - - - 6.508e-275 854.0
HFD2_k127_5328511_1 hydrolase activity, acting on ester bonds K01259,K18457 - 3.4.11.5,3.5.1.101 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 339.0
HFD2_k127_5328511_10 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.00000000000000000000000003204 121.0
HFD2_k127_5328511_11 - - - - 0.00000000000000000000002608 105.0
HFD2_k127_5328511_12 Transglutaminase-like superfamily - - - 0.00000000000000000000007642 115.0
HFD2_k127_5328511_13 - - - - 0.000002087 61.0
HFD2_k127_5328511_14 Carboxypeptidase regulatory-like domain - - - 0.0009685 48.0
HFD2_k127_5328511_2 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 319.0
HFD2_k127_5328511_3 nitrite reductase [NAD(P)H] activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 295.0
HFD2_k127_5328511_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004622 290.0
HFD2_k127_5328511_5 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000001378 259.0
HFD2_k127_5328511_6 DNA/RNA non-specific endonuclease K01173 - - 0.00000000000000000000000000000000000000000000009233 178.0
HFD2_k127_5328511_7 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000001913 172.0
HFD2_k127_5328511_9 Acetyl xylan esterase (AXE1) - - - 0.000000000000000000000000000000000000004002 152.0
HFD2_k127_534409_0 SPTR Transposase IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002231 262.0
HFD2_k127_534409_1 IS1 transposase K07480 - - 0.00000000005155 66.0
HFD2_k127_534409_2 COGs COG3677 Transposase and inactivated derivatives K07480 - - 0.000000005044 58.0
HFD2_k127_5355826_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1236.0
HFD2_k127_5355826_1 DNA internalization-related competence protein ComEC Rec2 K02238 - - 7.265e-292 918.0
HFD2_k127_5355826_10 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.00000000000000000000000001518 124.0
HFD2_k127_5355826_11 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.00000000000000000000000004785 111.0
HFD2_k127_5355826_12 YtxH-like protein - - - 0.0000000000000000000002297 99.0
HFD2_k127_5355826_2 acetylesterase activity - - - 1.59e-202 648.0
HFD2_k127_5355826_3 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 582.0
HFD2_k127_5355826_4 Glycosyltransferase family 28 C-terminal domain K03715 - 2.4.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 529.0
HFD2_k127_5355826_5 WD40 repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 541.0
HFD2_k127_5355826_6 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 507.0
HFD2_k127_5355826_7 gluconolactonase activity K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009638 385.0
HFD2_k127_5355826_8 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 350.0
HFD2_k127_5355826_9 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000000000000000001169 215.0
HFD2_k127_5385114_0 transport - - - 0.0 1057.0
HFD2_k127_5385114_1 Tetratricopeptide TPR_2 repeat protein - - - 9.083e-239 759.0
HFD2_k127_5385114_2 Peptidase family M28 - - - 1.364e-230 726.0
HFD2_k127_5385114_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 2.79e-220 692.0
HFD2_k127_5385114_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 418.0
HFD2_k127_5385114_5 Peptidase family S58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009906 415.0
HFD2_k127_5385114_6 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 327.0
HFD2_k127_5385114_7 Putative FMN-binding domain K07734 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002663 282.0
HFD2_k127_5385114_8 Beta-lactamase class C and other penicillin binding - - - 0.000000000000000000000000000000000000000000000106 180.0
HFD2_k127_5387106_0 Delta-1-pyrroline-5-carboxylate dehydrogenase K00294 - 1.2.1.88 3.948e-228 715.0
HFD2_k127_5387106_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 1.729e-205 644.0
HFD2_k127_5387106_2 PQQ-like domain K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 566.0
HFD2_k127_5387106_3 GHMP kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 364.0
HFD2_k127_5387106_4 Predicted methyltransferase regulatory domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007164 384.0
HFD2_k127_5387106_5 spheroidene biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 347.0
HFD2_k127_5387106_6 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 327.0
HFD2_k127_5387106_7 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001293 243.0
HFD2_k127_5405271_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 554.0
HFD2_k127_5405271_1 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 338.0
HFD2_k127_5405271_10 palmitoyl-(protein) hydrolase activity K06999 - - 0.000000000000000000000000000001262 130.0
HFD2_k127_5405271_11 SnoaL-like domain - - - 0.000000000000000000000000000007203 127.0
HFD2_k127_5405271_12 PFAM type IV pilus assembly PilZ - - - 0.0000000000000000000002871 101.0
HFD2_k127_5405271_13 4Fe-4S single cluster domain - - - 0.000000000000000000000337 101.0
HFD2_k127_5405271_15 gluconolactonase activity K07004,K14274 - - 0.00001147 57.0
HFD2_k127_5405271_2 Amidohydrolase family K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 322.0
HFD2_k127_5405271_3 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 310.0
HFD2_k127_5405271_4 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001652 282.0
HFD2_k127_5405271_5 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001233 256.0
HFD2_k127_5405271_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K04756 - - 0.000000000000000000000000000000000000000000000000000000000000000000001162 241.0
HFD2_k127_5405271_7 PFAM Lytic transglycosylase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000008772 216.0
HFD2_k127_5405271_8 Transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000000004011 160.0
HFD2_k127_5405271_9 Ferric uptake regulator family K09825 - - 0.00000000000000000000000000000000000002598 148.0
HFD2_k127_5408940_0 PFAM single-strand binding protein Primosomal replication protein n K03111 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944,GO:0097159,GO:1901363 - 0.00000000004396 68.0
HFD2_k127_5408940_1 Type IV secretion-system coupling protein DNA-binding domain - - - 0.000000007753 67.0
HFD2_k127_5408940_2 HEPN domain - - - 0.00002263 52.0
HFD2_k127_5414105_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 567.0
HFD2_k127_5414105_1 peptidylprolyl isomerase K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009614 432.0
HFD2_k127_5414105_10 PFAM Xanthine uracil vitamin C permease K06901 - - 0.0000000000000000004564 87.0
HFD2_k127_5414105_11 Hemerythrin HHE cation binding domain - - - 0.000000000002801 74.0
HFD2_k127_5414105_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 426.0
HFD2_k127_5414105_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 348.0
HFD2_k127_5414105_4 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 319.0
HFD2_k127_5414105_5 Mut7-C ubiquitin K09122 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 298.0
HFD2_k127_5414105_6 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000004517 215.0
HFD2_k127_5414105_8 hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000002423 124.0
HFD2_k127_5414105_9 Putative regulatory protein - - - 0.00000000000000000000000000006474 116.0
HFD2_k127_5425817_0 Pyridoxal-dependent decarboxylase conserved domain K01580,K01593,K13745 - 4.1.1.105,4.1.1.15,4.1.1.28,4.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 541.0
HFD2_k127_5425817_1 PFAM Cytochrome c assembly protein K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 495.0
HFD2_k127_5425817_2 Highly conserved protein containing a thioredoxin domain K06888,K20948 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 370.0
HFD2_k127_5425817_3 RNA pseudouridylate synthase K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 333.0
HFD2_k127_5425817_4 PFAM Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009829 326.0
HFD2_k127_5425817_5 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000000003471 216.0
HFD2_k127_5431742_0 PFAM Magnesium chelatase, ChlI subunit K07391 - - 9.222e-255 794.0
HFD2_k127_5431742_1 Carboxypeptidase regulatory-like domain - - - 1.061e-241 779.0
HFD2_k127_5431742_11 B-1 B cell differentiation - - - 0.000000000000000000000000000000000000000006033 173.0
HFD2_k127_5431742_12 Domain of unknown function (DUF4112) - - - 0.00000000000000000000000000000000000000001708 158.0
HFD2_k127_5431742_13 - - - - 0.000000000000000000000000000000000000003665 161.0
HFD2_k127_5431742_14 Glycosyltransferase Family 4 - - - 0.00000000000000000000000003433 108.0
HFD2_k127_5431742_15 -O-antigen - - - 0.00000000000001394 87.0
HFD2_k127_5431742_17 Domain of unknown function (DUF4962) K19051 GO:0003674,GO:0003824,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006082,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008201,GO:0009056,GO:0009057,GO:0009987,GO:0016829,GO:0016835,GO:0016837,GO:0030202,GO:0030203,GO:0030211,GO:0042597,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044464,GO:0047488,GO:0071704,GO:0097367,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1901681,GO:1903510 4.2.2.7,4.2.2.8 0.0000008717 57.0
HFD2_k127_5431742_18 - - - - 0.0000288 53.0
HFD2_k127_5431742_2 beta-1,4-mannooligosaccharide phosphorylase - - - 8.653e-238 742.0
HFD2_k127_5431742_3 transferase activity, transferring glycosyl groups K18785 - 2.4.1.319,2.4.1.320 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006754 578.0
HFD2_k127_5431742_4 MreB/Mbl protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 555.0
HFD2_k127_5431742_5 transferase activity, transferring glycosyl groups K00713,K06338 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006626 551.0
HFD2_k127_5431742_6 PFAM Mandelate racemase muconate lactonizing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008949 421.0
HFD2_k127_5431742_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 368.0
HFD2_k127_5431742_9 Domain of unknown function (DUF2760) - - - 0.000000000000000000000000000000000000000000000000000000000003617 212.0
HFD2_k127_5452099_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 3.615e-274 848.0
HFD2_k127_5452099_1 Carboxypeptidase regulatory-like domain - - - 1.836e-263 851.0
HFD2_k127_5452099_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 1.917e-216 678.0
HFD2_k127_5452099_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 615.0
HFD2_k127_5452099_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007847 577.0
HFD2_k127_5452099_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000000000000001987 215.0
HFD2_k127_5452099_6 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000002532 189.0
HFD2_k127_5472725_0 anaphase-promoting complex binding - - - 5.813e-278 871.0
HFD2_k127_5472725_1 belongs to the aldehyde dehydrogenase family K00128,K00130,K00146 - 1.2.1.3,1.2.1.39,1.2.1.8 1.707e-195 621.0
HFD2_k127_5472725_2 anaphase-promoting complex binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 464.0
HFD2_k127_5472725_3 anaphase-promoting complex binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008836 432.0
HFD2_k127_5472725_4 Ureide permease K05340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009742 400.0
HFD2_k127_5472725_5 NUDIX domain - - - 0.000000000000000000000000208 108.0
HFD2_k127_5472725_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000001602 90.0
HFD2_k127_5472725_8 NUDIX domain - - - 0.00003749 48.0
HFD2_k127_5476367_0 Cytochrome c554 and c-prime - - - 0.0 1303.0
HFD2_k127_5476367_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0 1137.0
HFD2_k127_5476367_2 ASPIC and UnbV - - - 8.221e-285 894.0
HFD2_k127_5476367_3 PFAM Uncharacterised conserved protein UCP033563 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 556.0
HFD2_k127_5476367_4 TonB C terminal - - - 0.0000000000000000000000000000000000000000000000000001704 189.0
HFD2_k127_5476367_5 HDOD domain - - - 0.0000000000000000000000000000000000000001977 162.0
HFD2_k127_5476367_6 Transcriptional regulatory protein, C terminal K02483 GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0098771 - 0.0005911 49.0
HFD2_k127_547797_0 Belongs to the glycosyl hydrolase 57 family - - - 9.883e-319 996.0
HFD2_k127_547797_1 Glycogen debranching enzyme N terminal - - - 9.317e-311 967.0
HFD2_k127_547797_2 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 1.058e-283 884.0
HFD2_k127_547797_3 Alpha amylase, catalytic domain K06044 - 5.4.99.15 3.885e-269 859.0
HFD2_k127_547797_4 PKD domain containing protein K01337,K20276,K21449 - 3.4.21.50 4.878e-250 807.0
HFD2_k127_547797_5 PFAM Sulfatase - - - 5.095e-196 621.0
HFD2_k127_547797_6 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 618.0
HFD2_k127_547797_7 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005556 496.0
HFD2_k127_547797_8 SMART alpha amylase, catalytic sub domain K05343 - 3.2.1.1,5.4.99.16 0.00000000007948 67.0
HFD2_k127_547797_9 Protein of unknown function (DUF2934) - - - 0.000002425 55.0
HFD2_k127_54800_0 Histidine kinase - - - 0.0 1373.0
HFD2_k127_54800_1 Peptidase M14, carboxypeptidase A - - - 0.0 1066.0
HFD2_k127_54800_10 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 526.0
HFD2_k127_54800_11 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 462.0
HFD2_k127_54800_12 PFAM peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 383.0
HFD2_k127_54800_13 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007558 368.0
HFD2_k127_54800_14 AAA domain K08252 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 374.0
HFD2_k127_54800_15 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 342.0
HFD2_k127_54800_16 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 340.0
HFD2_k127_54800_17 Beta-lactamase K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000009719 274.0
HFD2_k127_54800_18 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009189 259.0
HFD2_k127_54800_19 orotate phosphoribosyltransferase activity K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000001168 261.0
HFD2_k127_54800_2 Carboxypeptidase regulatory-like domain - - - 0.0 1039.0
HFD2_k127_54800_20 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002205 267.0
HFD2_k127_54800_21 Acetyltransferase (GNAT) domain K03817 - - 0.000000000000000000000000000000000000000000000000000000000000000001145 234.0
HFD2_k127_54800_22 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000006259 222.0
HFD2_k127_54800_23 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000000000000000000000000000000000000000000000000001156 203.0
HFD2_k127_54800_25 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000002967 197.0
HFD2_k127_54800_26 EVE domain - - - 0.000000000000000000000000000000000000000000000002261 178.0
HFD2_k127_54800_27 - - - - 0.00000000000000000000000000000000000001723 147.0
HFD2_k127_54800_3 two component, sigma54 specific, transcriptional regulator, Fis family - - - 7.013e-244 760.0
HFD2_k127_54800_30 domain protein K20276 - - 0.0000000000000000000000002356 121.0
HFD2_k127_54800_31 Protein of unknown function DUF86 - - - 0.00000000000000000000000186 106.0
HFD2_k127_54800_32 UPF0391 membrane protein - - - 0.0000000000002467 70.0
HFD2_k127_54800_33 PFAM DNA polymerase beta domain protein region K07075 - - 0.0000000000401 68.0
HFD2_k127_54800_35 nuclease activity K06218 - - 0.000000001279 62.0
HFD2_k127_54800_36 Bacterial protein of unknown function (DUF885) - - - 0.000000001766 68.0
HFD2_k127_54800_4 Outer membrane efflux protein - - - 7.601e-227 720.0
HFD2_k127_54800_5 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.255e-219 686.0
HFD2_k127_54800_6 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 561.0
HFD2_k127_54800_7 Chain length determinant protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008607 556.0
HFD2_k127_54800_8 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 546.0
HFD2_k127_54800_9 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 523.0
HFD2_k127_5481751_0 Carboxypeptidase regulatory-like domain - - - 0.0 1149.0
HFD2_k127_5481751_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 340.0
HFD2_k127_5481751_2 2OG-Fe(II) oxygenase K03919 - 1.14.11.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 300.0
HFD2_k127_5481751_3 RNA-binding S4 domain protein K04762 - - 0.000000000000000000000000000000000000000000000002075 181.0
HFD2_k127_5486982_0 Carboxypeptidase regulatory-like domain - - - 0.0 1038.0
HFD2_k127_5486982_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007516 455.0
HFD2_k127_5486982_2 acetyltransferase K03830 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 333.0
HFD2_k127_5486982_3 Abhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 296.0
HFD2_k127_5486982_4 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000005973 243.0
HFD2_k127_5486982_5 Surface antigen - - - 0.000000000000000000000000000006343 134.0
HFD2_k127_5486982_6 Zinc carboxypeptidase - - - 0.0000000000000000000000000001972 117.0
HFD2_k127_5486982_7 zinc ion binding - - - 0.0000000005511 60.0
HFD2_k127_5532335_0 PFAM Prenyltransferase squalene oxidase - - - 0.0 1249.0
HFD2_k127_5532335_1 PFAM ABC transporter K06158 - - 3.159e-312 966.0
HFD2_k127_5532335_10 PFAM amino acid permease-associated region K20265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 413.0
HFD2_k127_5532335_11 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 387.0
HFD2_k127_5532335_12 HpcH/HpaI aldolase/citrate lyase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 376.0
HFD2_k127_5532335_13 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 366.0
HFD2_k127_5532335_14 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003058 269.0
HFD2_k127_5532335_15 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001684 263.0
HFD2_k127_5532335_16 Mandelate racemase muconate lactonizing enzyme - - - 0.00000000000000000000000000000000000000000000001198 186.0
HFD2_k127_5532335_2 MacB-like periplasmic core domain K02004 - - 2.217e-207 665.0
HFD2_k127_5532335_3 Belongs to the BshC family K22136 - - 3.087e-207 658.0
HFD2_k127_5532335_4 carboxylic acid catabolic process K12661 - 4.2.1.90 6.422e-207 653.0
HFD2_k127_5532335_5 zinc metalloprotease K11749 - - 2.764e-203 640.0
HFD2_k127_5532335_6 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007932 565.0
HFD2_k127_5532335_7 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005444 505.0
HFD2_k127_5532335_8 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 498.0
HFD2_k127_5532335_9 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 454.0
HFD2_k127_5537201_0 - - - - 1.417e-197 642.0
HFD2_k127_5537201_1 Cytochrome c K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 492.0
HFD2_k127_5537201_2 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 448.0
HFD2_k127_5537201_3 Glycosyl hydrolase family 9 - - - 0.00000000000000000000000000000000000000000000000000000000000007268 234.0
HFD2_k127_5539537_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0 1367.0
HFD2_k127_5539537_1 Surface antigen variable number - - - 0.0 1231.0
HFD2_k127_5539537_10 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000000000000000007192 193.0
HFD2_k127_5539537_11 4Fe-4S binding domain K00176 - 1.2.7.3 0.0000000000000000000000000000000009015 131.0
HFD2_k127_5539537_12 peptidyl-prolyl cis-trans isomerase activity K00645,K01802,K02597,K03769,K03770,K03771 - 2.3.1.39,5.2.1.8 0.0000000000000000000000000003557 128.0
HFD2_k127_5539537_14 HicA toxin of bacterial toxin-antitoxin, - - - 0.0002475 49.0
HFD2_k127_5539537_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174 - 1.2.7.11,1.2.7.3 1.22e-201 633.0
HFD2_k127_5539537_3 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 577.0
HFD2_k127_5539537_4 MoeZ MoeB domain K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 475.0
HFD2_k127_5539537_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 472.0
HFD2_k127_5539537_6 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 453.0
HFD2_k127_5539537_7 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 327.0
HFD2_k127_5539537_8 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001049 285.0
HFD2_k127_5539537_9 NikR C terminal nickel binding domain K07722 - - 0.00000000000000000000000000000000000000000000000000000000000000000004933 235.0
HFD2_k127_5554636_0 TonB-dependent receptor - - - 0.0 1132.0
HFD2_k127_5554636_1 Prolyl oligopeptidase family - - - 0.0 1019.0
HFD2_k127_5554636_10 arylsulfatase activity K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 537.0
HFD2_k127_5554636_11 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 526.0
HFD2_k127_5554636_12 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 466.0
HFD2_k127_5554636_13 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 348.0
HFD2_k127_5554636_14 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 348.0
HFD2_k127_5554636_15 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002696 255.0
HFD2_k127_5554636_16 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000002897 233.0
HFD2_k127_5554636_17 Yip1 domain - - - 0.0000000000000000000000000000000000000000000000000000004742 201.0
HFD2_k127_5554636_18 Membrane - - - 0.0000000000000000000000000000000000000000000000000000033 196.0
HFD2_k127_5554636_19 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000002579 121.0
HFD2_k127_5554636_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.338e-305 944.0
HFD2_k127_5554636_20 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000001871 59.0
HFD2_k127_5554636_3 transport - - - 1.326e-252 818.0
HFD2_k127_5554636_4 Protein of unknown function (DUF229) - - - 2.257e-232 728.0
HFD2_k127_5554636_5 TonB-dependent Receptor Plug K02014 - - 1.783e-215 687.0
HFD2_k127_5554636_6 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 2.744e-210 670.0
HFD2_k127_5554636_7 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.973e-200 631.0
HFD2_k127_5554636_8 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 5.274e-199 626.0
HFD2_k127_5554636_9 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 553.0
HFD2_k127_5557622_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 8.347e-300 924.0
HFD2_k127_5557622_1 Caspase domain - - - 5.685e-279 874.0
HFD2_k127_5557622_10 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009988 312.0
HFD2_k127_5557622_11 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008172 289.0
HFD2_k127_5557622_12 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006757 286.0
HFD2_k127_5557622_13 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001104 278.0
HFD2_k127_5557622_15 Domain of unknown function (DUF4384) - - - 0.00000000000000000000000000000000000000000000000000000000000000000008877 242.0
HFD2_k127_5557622_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000008933 231.0
HFD2_k127_5557622_17 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000001258 224.0
HFD2_k127_5557622_18 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000000000008921 188.0
HFD2_k127_5557622_19 - - - - 0.000000000000000000000000000000000000000000000001066 182.0
HFD2_k127_5557622_2 PQQ-like domain K00114 - 1.1.2.8 9.059e-222 703.0
HFD2_k127_5557622_20 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000005319 163.0
HFD2_k127_5557622_21 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005576 - 0.000000000000000000000000000000000000000004454 160.0
HFD2_k127_5557622_22 - - - - 0.00000000000000000000000000000000000006802 147.0
HFD2_k127_5557622_23 acylphosphatase activity K01512 - 3.6.1.7 0.00000000000000000000000000000007957 128.0
HFD2_k127_5557622_25 - - - - 0.0000000000000000001025 91.0
HFD2_k127_5557622_26 phosphoserine phosphatase activity K07711 - 2.7.13.3 0.0000000000932 70.0
HFD2_k127_5557622_3 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K09774 - - 2.374e-219 704.0
HFD2_k127_5557622_4 PKD domain containing protein K01337,K20276,K21449 - 3.4.21.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 636.0
HFD2_k127_5557622_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 507.0
HFD2_k127_5557622_6 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 413.0
HFD2_k127_5557622_7 PFAM ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 407.0
HFD2_k127_5557622_8 GHMP kinases N terminal domain K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 359.0
HFD2_k127_5557622_9 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 345.0
HFD2_k127_5602578_0 Carboxypeptidase regulatory-like domain - - - 0.0 1144.0
HFD2_k127_5602578_1 GTP-binding protein TypA K06207 - - 3.56e-322 992.0
HFD2_k127_5602578_11 Transglutaminase-like superfamily - - - 0.000000000005743 69.0
HFD2_k127_5602578_2 efflux transmembrane transporter activity K02004 - - 4.748e-318 994.0
HFD2_k127_5602578_3 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 606.0
HFD2_k127_5602578_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 344.0
HFD2_k127_5602578_5 lipoprotein transporter activity K02003,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 321.0
HFD2_k127_5602578_6 PFAM Formylglycine-generating sulfatase enzyme K03496,K12055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004552 333.0
HFD2_k127_5602578_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 317.0
HFD2_k127_5602578_8 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000002156 234.0
HFD2_k127_5602578_9 Elongation factor P K02356 - - 0.00000000000000000000000000000000000000000004858 166.0
HFD2_k127_560732_0 PFAM Integrase catalytic - - - 4.328e-218 685.0
HFD2_k127_560732_1 ParB-like nuclease domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 559.0
HFD2_k127_560732_3 IstB-like ATP binding protein - - - 0.00000000000000003413 86.0
HFD2_k127_560732_4 Resolvase, N terminal domain - - - 0.000392 44.0
HFD2_k127_561671_0 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 485.0
HFD2_k127_561671_1 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000435 264.0
HFD2_k127_5621593_0 Phosphoesterase family - - - 2.782e-275 858.0
HFD2_k127_5621593_1 TonB-dependent receptor - - - 1.63e-259 833.0
HFD2_k127_5621593_10 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009033 401.0
HFD2_k127_5621593_11 PFAM ATP-binding region, ATPase domain protein domain protein K07683 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001156 293.0
HFD2_k127_5621593_12 PFAM Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001918 277.0
HFD2_k127_5621593_13 haloacid dehalogenase-like hydrolase K07026 - 3.1.3.70 0.00000000000000000000000000000000000000000000000000000000000000005307 233.0
HFD2_k127_5621593_14 - - - - 0.0000000000000000000000000000000000000000000000000001881 186.0
HFD2_k127_5621593_15 RNA recognition motif - - - 0.0000000000000000000000000000000000000000000000000009705 185.0
HFD2_k127_5621593_16 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000001153 175.0
HFD2_k127_5621593_18 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000001189 141.0
HFD2_k127_5621593_19 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000001745 143.0
HFD2_k127_5621593_2 two component, sigma54 specific, transcriptional regulator, Fis family - - - 8.939e-222 694.0
HFD2_k127_5621593_20 - - - - 0.000000000000000000000002342 107.0
HFD2_k127_5621593_21 Adenylate cyclase - - - 0.0000000000000000000000119 108.0
HFD2_k127_5621593_22 transmembrane transport - - - 0.0000000000000003885 88.0
HFD2_k127_5621593_23 - - - - 0.00000000000004111 75.0
HFD2_k127_5621593_3 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 1.749e-221 694.0
HFD2_k127_5621593_4 Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 610.0
HFD2_k127_5621593_5 phosphorelay sensor kinase activity K07709,K07710 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 551.0
HFD2_k127_5621593_6 Cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 519.0
HFD2_k127_5621593_7 Glycosyl transferase, family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 490.0
HFD2_k127_5621593_8 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 487.0
HFD2_k127_5621593_9 surface antigen K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 464.0
HFD2_k127_5650090_0 beta-galactosidase activity - - - 8.279e-244 772.0
HFD2_k127_5650090_1 Putative esterase - - - 4.785e-207 659.0
HFD2_k127_5650090_2 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 569.0
HFD2_k127_5650090_3 Outer membrane efflux protein K12340,K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007723 356.0
HFD2_k127_5650090_4 L-seryl-tRNASec selenium transferase activity K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000007783 267.0
HFD2_k127_5650090_5 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000001403 215.0
HFD2_k127_5650090_6 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000005183 75.0
HFD2_k127_5658493_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 562.0
HFD2_k127_5658493_1 PFAM secretion protein HlyD family protein K02005,K02022 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 458.0
HFD2_k127_5658493_2 PFAM secretion protein HlyD family protein K02005,K02022 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 411.0
HFD2_k127_5658493_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 381.0
HFD2_k127_5658493_4 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 360.0
HFD2_k127_5658493_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 292.0
HFD2_k127_5658493_6 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000000000004802 196.0
HFD2_k127_5658493_7 lytic transglycosylase activity - - - 0.000000000000000000000000000000000000000289 156.0
HFD2_k127_5682571_0 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 1.132e-197 627.0
HFD2_k127_5682571_1 Membrane-bound dehydrogenase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 612.0
HFD2_k127_5682571_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 388.0
HFD2_k127_5682571_3 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 351.0
HFD2_k127_5682571_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000001245 85.0
HFD2_k127_5682571_6 hydroperoxide reductase activity K07486 - - 0.00000000000419 75.0
HFD2_k127_5682571_7 Glycosyl hydrolases family 8 K15531 - 3.2.1.156 0.00000000007119 74.0
HFD2_k127_5686729_0 TonB-dependent receptor - - - 8.005e-274 880.0
HFD2_k127_5686729_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.421e-266 825.0
HFD2_k127_5686729_10 cell adhesion involved in biofilm formation - - - 2.199e-202 671.0
HFD2_k127_5686729_11 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 9.738e-202 633.0
HFD2_k127_5686729_12 Domain of unknown function (DUF4976) - - - 1.35e-199 634.0
HFD2_k127_5686729_13 - - - - 6.264e-198 622.0
HFD2_k127_5686729_14 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 9.51e-196 614.0
HFD2_k127_5686729_15 family 2 sugar binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 649.0
HFD2_k127_5686729_16 synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 544.0
HFD2_k127_5686729_17 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008469 462.0
HFD2_k127_5686729_18 Transcriptional regulator, LysR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 461.0
HFD2_k127_5686729_19 Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 442.0
HFD2_k127_5686729_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014,K13832 - 1.1.1.25,4.2.1.10 4.476e-254 791.0
HFD2_k127_5686729_20 symporter activity K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 394.0
HFD2_k127_5686729_21 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 404.0
HFD2_k127_5686729_22 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008098 340.0
HFD2_k127_5686729_23 IclR helix-turn-helix domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 304.0
HFD2_k127_5686729_24 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 280.0
HFD2_k127_5686729_25 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001045 281.0
HFD2_k127_5686729_26 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001303 293.0
HFD2_k127_5686729_27 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001104 288.0
HFD2_k127_5686729_28 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000009851 267.0
HFD2_k127_5686729_29 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000003132 246.0
HFD2_k127_5686729_3 COG3119 Arylsulfatase A K01138 - - 3.267e-235 743.0
HFD2_k127_5686729_30 RNase H K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000008078 228.0
HFD2_k127_5686729_31 pyrroloquinoline quinone binding K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000002307 205.0
HFD2_k127_5686729_32 Low affinity iron permease - - - 0.000000000000000000000000000000000000000009226 157.0
HFD2_k127_5686729_4 PFAM Glucuronate isomerase K01812 - 5.3.1.12 5.612e-232 740.0
HFD2_k127_5686729_5 L-arabinose isomerase - - - 4.718e-223 702.0
HFD2_k127_5686729_6 Amidase - - - 5.477e-218 688.0
HFD2_k127_5686729_7 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 4.343e-213 666.0
HFD2_k127_5686729_8 - - - - 5.681e-207 649.0
HFD2_k127_5686729_9 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K15372 - 2.6.1.19,2.6.1.55 1.006e-205 647.0
HFD2_k127_5687574_0 Carboxypeptidase regulatory-like domain - - - 0.0 1049.0
HFD2_k127_5687574_1 Protein of unknown function (DUF1501) - - - 7.963e-200 629.0
HFD2_k127_5687574_10 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000002365 220.0
HFD2_k127_5687574_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 627.0
HFD2_k127_5687574_3 COG3119 Arylsulfatase A and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 518.0
HFD2_k127_5687574_4 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 392.0
HFD2_k127_5687574_5 PFAM KWG Leptospira - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 299.0
HFD2_k127_5687574_6 metallopeptidase activity K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 299.0
HFD2_k127_5687574_7 PFAM Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001209 272.0
HFD2_k127_5687574_8 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002235 241.0
HFD2_k127_5687574_9 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000001508 228.0
HFD2_k127_5695973_0 protoporphyrinogen oxidase activity K01854,K07011 - 5.4.99.9 0.0 1250.0
HFD2_k127_5695973_1 Belongs to the glycosyl hydrolase 2 family - - - 2.47e-322 994.0
HFD2_k127_5695973_10 - - - - 0.0000000000000000000000000000000000000002306 151.0
HFD2_k127_5695973_11 Subtilase family - - - 0.000000000000000000000000000000008485 134.0
HFD2_k127_5695973_12 - - - - 0.00000000000000000000000000000284 124.0
HFD2_k127_5695973_13 - - - - 0.0000000000000000000345 94.0
HFD2_k127_5695973_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.794e-220 692.0
HFD2_k127_5695973_3 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 595.0
HFD2_k127_5695973_4 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 551.0
HFD2_k127_5695973_5 6-phospho-beta-galactosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000856 498.0
HFD2_k127_5695973_6 Dehydrogenase E1 component K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 483.0
HFD2_k127_5695973_7 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 418.0
HFD2_k127_5695973_8 phosphorelay signal transduction system K10941 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 341.0
HFD2_k127_5695973_9 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002908 259.0
HFD2_k127_5721483_0 Carboxypeptidase regulatory-like domain - - - 1.548e-255 831.0
HFD2_k127_5721483_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 8.579e-204 642.0
HFD2_k127_5721483_10 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 357.0
HFD2_k127_5721483_11 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 348.0
HFD2_k127_5721483_12 PFAM GCN5-related N-acetyltransferase K00619 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000105 256.0
HFD2_k127_5721483_13 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000105 225.0
HFD2_k127_5721483_14 zinc D-Ala-D-Ala carboxypeptidase activity K08641 - 3.4.13.22 0.00000000000000000000000000000000000000000000000000000009814 209.0
HFD2_k127_5721483_15 TM2 domain - - - 0.00000000000000000000000000000000000000000000000000001252 192.0
HFD2_k127_5721483_16 alginic acid biosynthetic process K01729 - 4.2.2.3 0.000000000000000000000000000000000002293 154.0
HFD2_k127_5721483_17 Histidine kinase - - - 0.000000000000000000000000000000002658 151.0
HFD2_k127_5721483_18 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate K01815 - 5.3.1.17 0.000002071 59.0
HFD2_k127_5721483_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.64e-197 620.0
HFD2_k127_5721483_3 'Molybdopterin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000637 574.0
HFD2_k127_5721483_4 PFAM Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 560.0
HFD2_k127_5721483_5 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 514.0
HFD2_k127_5721483_6 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 481.0
HFD2_k127_5721483_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 457.0
HFD2_k127_5721483_8 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K18983 - 5.5.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 374.0
HFD2_k127_5721483_9 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 355.0
HFD2_k127_5743543_0 -O-antigen K02847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 461.0
HFD2_k127_5743543_1 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 435.0
HFD2_k127_5743543_10 3-beta hydroxysteroid dehydrogenase/isomerase family K22252 - 1.1.1.135 0.0000000000000000000000000000000000000000000000000000006365 218.0
HFD2_k127_5743543_11 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000001457 215.0
HFD2_k127_5743543_12 CoA-binding domain K00996 - 2.7.8.6 0.00000000000000000000000000000000000000000000000003993 188.0
HFD2_k127_5743543_13 glycosyl transferase group 1 K13668 - 2.4.1.346 0.000000000000000000000000000000000000000000000005883 189.0
HFD2_k127_5743543_14 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000003173 150.0
HFD2_k127_5743543_15 PFAM Glycosyl transferase, group 1 K21001 - - 0.0000000000000000000000007138 121.0
HFD2_k127_5743543_16 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00000000000000006338 93.0
HFD2_k127_5743543_17 transferase activity, transferring glycosyl groups - - - 0.00002437 56.0
HFD2_k127_5743543_18 Glycosyl transferase 4-like domain - - - 0.0003365 45.0
HFD2_k127_5743543_2 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 384.0
HFD2_k127_5743543_3 -O-antigen K02847,K13009 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 355.0
HFD2_k127_5743543_4 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 335.0
HFD2_k127_5743543_5 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 305.0
HFD2_k127_5743543_6 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002352 254.0
HFD2_k127_5743543_7 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004773 246.0
HFD2_k127_5743543_8 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000002264 252.0
HFD2_k127_5743543_9 extracellular polysaccharide biosynthetic process K01153 - 3.1.21.3 0.000000000000000000000000000000000000000000000000000000000000000001936 241.0
HFD2_k127_5762729_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756,K01857 - 4.3.2.2,5.5.1.2 2.449e-230 722.0
HFD2_k127_5762729_1 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 571.0
HFD2_k127_5762729_10 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000002855 177.0
HFD2_k127_5762729_11 O-methyltransferase - - - 0.00000000000000000000000000000000000000000009941 173.0
HFD2_k127_5762729_12 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000005098 151.0
HFD2_k127_5762729_13 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000001345 159.0
HFD2_k127_5762729_14 Methyltransferase domain K00588 - 2.1.1.104 0.000000618 51.0
HFD2_k127_5762729_2 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 498.0
HFD2_k127_5762729_3 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006167 446.0
HFD2_k127_5762729_4 aldo keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 368.0
HFD2_k127_5762729_5 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 371.0
HFD2_k127_5762729_6 ADP-L-glycero-beta-D-manno-heptose biosynthetic process K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 319.0
HFD2_k127_5762729_7 SIS domain K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 282.0
HFD2_k127_5762729_8 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000004146 238.0
HFD2_k127_5762729_9 PFAM Cupin - - - 0.000000000000000000000000000000000000000000000000000001188 194.0
HFD2_k127_5773758_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 595.0
HFD2_k127_5773758_1 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 577.0
HFD2_k127_5773758_2 response to copper ion K01187,K16915 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 346.0
HFD2_k127_5773758_3 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008994 243.0
HFD2_k127_5773758_4 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000569 94.0
HFD2_k127_5774450_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 486.0
HFD2_k127_5774450_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000005227 214.0
HFD2_k127_5774450_2 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000002008 190.0
HFD2_k127_5774450_3 adenylylsulfate kinase activity K00860,K00958,K22424 - 2.7.1.25,2.7.3.13,2.7.7.4 0.0000000000000000000000000000000000000003152 161.0
HFD2_k127_5774450_4 - - - - 0.00000000000000000005114 90.0
HFD2_k127_5775224_0 PFAM Radical SAM - - - 0.0 1272.0
HFD2_k127_5775224_1 Radical SAM superfamily K06937 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007152 494.0
HFD2_k127_5775224_10 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000002668 158.0
HFD2_k127_5775224_11 Belongs to the tRNA nucleotidyltransferase poly(A) polymerase family - - - 0.00000000000000000000000000000000000006599 146.0
HFD2_k127_5775224_12 with the TIM-barrel fold - - - 0.000000000000000000000000000000000001022 151.0
HFD2_k127_5775224_13 O-methyltransferase - - - 0.00000000000000000000000000000001058 143.0
HFD2_k127_5775224_14 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000001273 136.0
HFD2_k127_5775224_15 Bacterial PH domain K08981 - - 0.0000000000000000000000000001376 120.0
HFD2_k127_5775224_16 PFAM S23 ribosomal protein - - - 0.000000000000000001665 89.0
HFD2_k127_5775224_17 PrpF protein - - - 0.0000000000004851 80.0
HFD2_k127_5775224_18 Protein of unknown function (DUF692) K09930 - - 0.00000000008029 74.0
HFD2_k127_5775224_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009381 489.0
HFD2_k127_5775224_3 Radical SAM superfamily K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 465.0
HFD2_k127_5775224_4 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006839 470.0
HFD2_k127_5775224_5 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 444.0
HFD2_k127_5775224_6 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 379.0
HFD2_k127_5775224_7 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 376.0
HFD2_k127_5775224_8 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 372.0
HFD2_k127_5775224_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007965 368.0
HFD2_k127_5815598_0 ECF sigma factor - - - 0.000000000000000000000000000000000000000001547 164.0
HFD2_k127_5815598_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000001091 74.0
HFD2_k127_5815598_2 Transglycosylase associated protein - - - 0.0001179 51.0
HFD2_k127_5830756_0 Carboxypeptidase regulatory-like domain - - - 0.0 1891.0
HFD2_k127_5830756_1 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 514.0
HFD2_k127_5830756_10 PFAM Isochorismatase - - - 0.00000000000000000000000000000000000000000000000000009736 191.0
HFD2_k127_5830756_11 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000002898 181.0
HFD2_k127_5830756_12 Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine - - - 0.0000000000000000000000000000000000000000003472 168.0
HFD2_k127_5830756_13 - - - - 0.0000000000000000000000000000000000000000724 159.0
HFD2_k127_5830756_14 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000002696 118.0
HFD2_k127_5830756_15 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.000000000000000000001778 100.0
HFD2_k127_5830756_16 Glycosyl Hydrolase Family 88 - - - 0.000000000003501 78.0
HFD2_k127_5830756_17 X-Pro dipeptidyl-peptidase (S15 family) K06889,K07397 - - 0.0005137 51.0
HFD2_k127_5830756_2 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 407.0
HFD2_k127_5830756_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006342 386.0
HFD2_k127_5830756_4 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms K14205 - 2.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 384.0
HFD2_k127_5830756_5 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 352.0
HFD2_k127_5830756_6 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 316.0
HFD2_k127_5830756_7 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 301.0
HFD2_k127_5830756_8 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004268 274.0
HFD2_k127_5830756_9 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000000000000000000004405 199.0
HFD2_k127_5835815_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534,K17686 - 3.6.3.3,3.6.3.5,3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 620.0
HFD2_k127_5835815_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007336 593.0
HFD2_k127_5835815_10 - - - - 0.00005941 48.0
HFD2_k127_5835815_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 589.0
HFD2_k127_5835815_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 457.0
HFD2_k127_5835815_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 439.0
HFD2_k127_5835815_5 Pectate lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 322.0
HFD2_k127_5835815_6 SPFH Band 7 PHB domain protein K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008449 252.0
HFD2_k127_5835815_7 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000299 226.0
HFD2_k127_5835815_8 - - - - 0.000000000000000000000000000000118 128.0
HFD2_k127_5839655_0 Carboxypeptidase regulatory-like domain - - - 7.429e-308 1004.0
HFD2_k127_5839655_1 protocatechuate 3,4-dioxygenase activity - - - 2.192e-254 824.0
HFD2_k127_5839655_10 Arginase family K01476 - 3.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 462.0
HFD2_k127_5839655_12 PFAM Xylose isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 408.0
HFD2_k127_5839655_13 PFAM secretion protein HlyD family protein K02005,K16922 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000936 378.0
HFD2_k127_5839655_14 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 360.0
HFD2_k127_5839655_15 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 300.0
HFD2_k127_5839655_16 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000001491 194.0
HFD2_k127_5839655_17 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000000000000000000000263 186.0
HFD2_k127_5839655_18 FtsX-like permease family - - - 0.0000000000000000000000000000002942 132.0
HFD2_k127_5839655_19 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000004458 65.0
HFD2_k127_5839655_2 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - - 2.807e-247 784.0
HFD2_k127_5839655_3 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 4.516e-245 767.0
HFD2_k127_5839655_4 class II (D K K01893 - 6.1.1.22 1.66e-236 740.0
HFD2_k127_5839655_5 PFAM Sulfatase - - - 2.051e-234 733.0
HFD2_k127_5839655_6 Belongs to the glycosyl hydrolase 3 family K05349,K17641 - 3.2.1.21 4.443e-209 674.0
HFD2_k127_5839655_7 Radical SAM superfamily K06871 - - 2.936e-206 654.0
HFD2_k127_5839655_8 Belongs to the glycosyl hydrolase 3 family K05349,K17641 - 3.2.1.21 2.715e-199 640.0
HFD2_k127_5839655_9 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 509.0
HFD2_k127_5843079_0 transport - - - 0.0 1260.0
HFD2_k127_5843079_1 transport - - - 0.0 1216.0
HFD2_k127_5843079_10 Belongs to the purine-cytosine permease (2.A.39) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 479.0
HFD2_k127_5843079_11 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000095 466.0
HFD2_k127_5843079_12 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008409 454.0
HFD2_k127_5843079_13 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 424.0
HFD2_k127_5843079_14 Pfam Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 405.0
HFD2_k127_5843079_15 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 364.0
HFD2_k127_5843079_16 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 338.0
HFD2_k127_5843079_17 Major facilitator Superfamily K02511,K02575,K13021 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 339.0
HFD2_k127_5843079_18 Bacterial transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006042 330.0
HFD2_k127_5843079_19 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 319.0
HFD2_k127_5843079_2 Dehydrogenase K00114,K17760,K20936,K21676,K22473 - 1.1.2.8,1.1.2.9,1.1.5.5,1.1.9.1,1.17.2.2 4.889e-278 879.0
HFD2_k127_5843079_20 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009357 310.0
HFD2_k127_5843079_21 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000000000000000000000000000000006949 186.0
HFD2_k127_5843079_22 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000002858 154.0
HFD2_k127_5843079_23 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000002322 135.0
HFD2_k127_5843079_24 Aldo/keto reductase family - - - 0.0000000000009766 79.0
HFD2_k127_5843079_25 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000006399 58.0
HFD2_k127_5843079_3 Carboxypeptidase regulatory-like domain - - - 9.332e-216 710.0
HFD2_k127_5843079_4 carboxylic acid catabolic process - - - 6.548e-209 659.0
HFD2_k127_5843079_5 COG3119 Arylsulfatase A - - - 7.585e-203 642.0
HFD2_k127_5843079_6 electron transfer activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 606.0
HFD2_k127_5843079_7 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006438 586.0
HFD2_k127_5843079_8 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 578.0
HFD2_k127_5843079_9 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 566.0
HFD2_k127_5846533_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0 2079.0
HFD2_k127_5846533_1 efflux transmembrane transporter activity - - - 7.769e-297 932.0
HFD2_k127_5846533_2 histidine kinase A domain protein domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 437.0
HFD2_k127_5846533_3 PFAM glycosyl transferase family 9 K02841 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 409.0
HFD2_k127_5846533_4 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 404.0
HFD2_k127_5846533_5 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005104 246.0
HFD2_k127_5846533_6 DinB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002887 243.0
HFD2_k127_5846533_7 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000001414 127.0
HFD2_k127_5853741_0 Peptidase S46 - - - 1.407e-233 743.0
HFD2_k127_5853741_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 2.002e-231 730.0
HFD2_k127_5853741_2 TonB-dependent Receptor Plug Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 611.0
HFD2_k127_5853741_3 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 568.0
HFD2_k127_5853741_4 hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 396.0
HFD2_k127_5853741_5 PFAM Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 319.0
HFD2_k127_5853741_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000009834 218.0
HFD2_k127_5853741_7 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000002033 160.0
HFD2_k127_5853741_8 - - - - 0.000000000000000000000000000003674 121.0
HFD2_k127_5859204_0 Alpha-L-fucosidase C-terminal domain - - - 5.571e-209 662.0
HFD2_k127_5859204_1 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 579.0
HFD2_k127_5859204_10 polysaccharide deacetylase - - - 0.0000000000000000001184 95.0
HFD2_k127_5859204_11 amine dehydrogenase activity - - - 0.000000000000000002559 87.0
HFD2_k127_5859204_2 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 501.0
HFD2_k127_5859204_3 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 419.0
HFD2_k127_5859204_4 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 361.0
HFD2_k127_5859204_5 Psort location Cytoplasmic, score 8.87 K02564 - 3.5.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000008077 249.0
HFD2_k127_5859204_6 phosphatidate phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000003756 245.0
HFD2_k127_5859204_7 LssY C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000007598 219.0
HFD2_k127_5859204_8 antisigma factor binding - - - 0.000000000000000000000000000000000000000000002212 175.0
HFD2_k127_5859204_9 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000000000000000000000000008221 166.0
HFD2_k127_5863550_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 556.0
HFD2_k127_5863550_1 Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 495.0
HFD2_k127_5863550_2 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00847,K00852 GO:0003674,GO:0003824,GO:0004747,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019303,GO:0019321,GO:0019323,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0071704,GO:1901575 2.7.1.15,2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008166 369.0
HFD2_k127_5863550_3 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K17763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 354.0
HFD2_k127_5863550_4 Stage II sporulation protein E - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 316.0
HFD2_k127_5863550_5 Protein of unknown function (DUF507) K09804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003564 277.0
HFD2_k127_5863550_6 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000001991 207.0
HFD2_k127_5863550_7 PFAM ATP-binding region, ATPase domain protein K17752 - 2.7.11.1 0.000000000000000000000000000000000000000000000000002202 188.0
HFD2_k127_5863550_8 PFAM Sulphate transporter antisigma-factor antagonist STAS K17762 - - 0.000000000000000000000000000000000000000000000005306 184.0
HFD2_k127_5866352_0 Angiotensin-converting enzyme K01283 - 3.4.15.1 1.005e-220 719.0
HFD2_k127_5866352_1 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 387.0
HFD2_k127_5866352_2 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000012 293.0
HFD2_k127_5866352_3 YXWGXW repeat (2 copies) - - - 0.000000000000000000000000002437 116.0
HFD2_k127_5866352_4 DinB family - - - 0.00000000000003524 80.0
HFD2_k127_587537_0 PFAM sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 387.0
HFD2_k127_587537_1 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000000004197 207.0
HFD2_k127_587537_2 dihydrofolate reductase activity - - - 0.00000000000000000004362 93.0
HFD2_k127_587537_3 YCII-related domain - - - 0.0000102 49.0
HFD2_k127_587537_4 PDZ domain (Also known as DHR or GLGF) K08372 - - 0.0007058 50.0
HFD2_k127_5877191_0 ImcF-related N-terminal domain K11891 - - 0.0 1143.0
HFD2_k127_5877191_1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 604.0
HFD2_k127_5877191_2 Type VI secretion system protein DotU K11892 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002829 277.0
HFD2_k127_5877191_3 - - - - 0.00000000005405 67.0
HFD2_k127_5895295_0 Prokaryotic cytochrome b561 - - - 2.369e-241 764.0
HFD2_k127_5895295_1 Sigma-54 interaction domain - - - 4.738e-236 735.0
HFD2_k127_5895295_2 NapC/NirT cytochrome c family, N-terminal region - - - 1.635e-219 691.0
HFD2_k127_5895295_3 PFAM peptidase - - - 6.02e-201 639.0
HFD2_k127_5895295_4 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 402.0
HFD2_k127_5895295_5 VWA domain containing CoxE-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 358.0
HFD2_k127_5895295_6 PKD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 350.0
HFD2_k127_5895295_7 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007869 342.0
HFD2_k127_5895295_8 Carboxylesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002854 283.0
HFD2_k127_5895295_9 Tellurite resistance protein TerB - - - 0.0000000000000000000000000000000000000000000000000000000000000002292 241.0
HFD2_k127_5895514_0 PFAM Thiamine pyrophosphate K01652 - 2.2.1.6 7.991e-313 966.0
HFD2_k127_5895514_1 4 iron, 4 sulfur cluster binding - - - 4.301e-296 916.0
HFD2_k127_5895514_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 579.0
HFD2_k127_5895514_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 329.0
HFD2_k127_5895514_4 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002788 268.0
HFD2_k127_5912750_0 E-Z type HEAT repeats - - - 2.601e-273 892.0
HFD2_k127_5912750_1 PQQ-like domain K00114 - 1.1.2.8 2.649e-270 853.0
HFD2_k127_5912750_10 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000007801 258.0
HFD2_k127_5912750_11 Abhydrolase family - - - 0.00000000000000000000000000000000000000000000002649 194.0
HFD2_k127_5912750_12 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000003481 100.0
HFD2_k127_5912750_2 transport - - - 5.191e-243 788.0
HFD2_k127_5912750_3 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 527.0
HFD2_k127_5912750_4 Oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007109 510.0
HFD2_k127_5912750_5 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008515 456.0
HFD2_k127_5912750_6 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 425.0
HFD2_k127_5912750_7 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 394.0
HFD2_k127_5912750_8 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006304 312.0
HFD2_k127_5912750_9 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000119 276.0
HFD2_k127_5927231_0 tail sheath protein - - - 0.0 1030.0
HFD2_k127_5927231_1 Sodium:solute symporter family - - - 3.673e-229 724.0
HFD2_k127_5927231_10 PFAM oxidoreductase domain protein K00010 - 1.1.1.18,1.1.1.369 0.000000000000000000000000000000000000000000000000000000000000000000000006124 256.0
HFD2_k127_5927231_11 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002482 252.0
HFD2_k127_5927231_12 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.00000000000000000000000000000000000000000000000000000000000008748 244.0
HFD2_k127_5927231_13 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000000000000000003218 138.0
HFD2_k127_5927231_2 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 1.455e-223 705.0
HFD2_k127_5927231_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.119e-197 620.0
HFD2_k127_5927231_4 alginic acid biosynthetic process K01729 - 4.2.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 513.0
HFD2_k127_5927231_5 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006645 440.0
HFD2_k127_5927231_6 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 368.0
HFD2_k127_5927231_7 2Fe-2S -binding K13483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 316.0
HFD2_k127_5927231_8 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 327.0
HFD2_k127_5927231_9 Domain of unknown function (DUF4962) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001061 297.0
HFD2_k127_592785_0 - - - - 0.0 1512.0
HFD2_k127_592785_1 - - - - 6.716e-315 991.0
HFD2_k127_592785_10 - - - - 0.0000000000002621 74.0
HFD2_k127_592785_2 Tetratricopeptide repeat - - - 8.984e-283 890.0
HFD2_k127_592785_3 protein transport across the cell outer membrane K02453,K03219 - - 9.98e-247 781.0
HFD2_k127_592785_4 SpoIVB peptidase S55 - - - 1.594e-244 767.0
HFD2_k127_592785_5 Oxidoreductase family, C-terminal alpha/beta domain K13020 - 1.1.1.335 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 588.0
HFD2_k127_592785_6 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 533.0
HFD2_k127_592785_7 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 532.0
HFD2_k127_592785_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000001568 181.0
HFD2_k127_592785_9 Domain of unknown function (DUF4252) - - - 0.000000000000000000000000000000000000000000000001576 182.0
HFD2_k127_5961485_0 beta-galactosidase activity - - - 0.0 1059.0
HFD2_k127_5961485_1 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 552.0
HFD2_k127_5961485_2 ATPase activity K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 519.0
HFD2_k127_5961485_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005362 395.0
HFD2_k127_5961485_4 Belongs to the LDH MDH superfamily. LDH family K00016,K00024 - 1.1.1.27,1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 344.0
HFD2_k127_5961485_5 siderophore transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 319.0
HFD2_k127_5961485_6 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000391 195.0
HFD2_k127_5961485_7 Penicillinase repressor - - - 0.00000000000000000000000000000000002235 150.0
HFD2_k127_5961485_8 BlaR1 peptidase M56 - - - 0.000000000000000000000000000005073 139.0
HFD2_k127_5961485_9 TIGRFAM TonB family K03832 - - 0.000000000000000000000000001005 131.0
HFD2_k127_5963473_0 Belongs to the GSP D family K02453 - - 3.713e-283 893.0
HFD2_k127_5963473_1 Dienelactone hydrolase family - - - 1.815e-257 811.0
HFD2_k127_5963473_10 transferase activity, transferring glycosyl groups K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 529.0
HFD2_k127_5963473_11 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 494.0
HFD2_k127_5963473_12 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 494.0
HFD2_k127_5963473_13 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 452.0
HFD2_k127_5963473_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 420.0
HFD2_k127_5963473_15 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 413.0
HFD2_k127_5963473_16 BNR repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 383.0
HFD2_k127_5963473_17 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006643 326.0
HFD2_k127_5963473_18 Fibronectin type III domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 319.0
HFD2_k127_5963473_19 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000000000000000000000000000005528 228.0
HFD2_k127_5963473_2 Peptidase M14, carboxypeptidase A - - - 8.283e-224 723.0
HFD2_k127_5963473_20 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000000005716 218.0
HFD2_k127_5963473_21 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000268 208.0
HFD2_k127_5963473_22 Type II secretion system protein G K02456 - - 0.0000000000000000000000000000000000000000000000001134 184.0
HFD2_k127_5963473_23 InterPro IPR007367 - - - 0.0000000000000000000000000000000000000000000109 175.0
HFD2_k127_5963473_24 - - - - 0.000000000000000000000000000000000001793 140.0
HFD2_k127_5963473_25 - - - - 0.00000000000000000000000000000001965 128.0
HFD2_k127_5963473_26 Peptidoglycan-binding domain 1 protein K01185,K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.2.1.17,3.5.1.28 0.000000000000000000000136 104.0
HFD2_k127_5963473_27 - - - - 0.00000000000001614 88.0
HFD2_k127_5963473_3 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 1.073e-222 702.0
HFD2_k127_5963473_4 PFAM AMP-dependent synthetase and ligase K12429,K18660,K18661,K18662 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 - 5.134e-222 696.0
HFD2_k127_5963473_5 benzoyl-CoA oxygenase K15512 - 1.14.13.208 1.761e-213 681.0
HFD2_k127_5963473_6 pentaerythritol trinitrate reductase activity - - - 1.27e-206 652.0
HFD2_k127_5963473_7 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 2.352e-204 651.0
HFD2_k127_5963473_8 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 576.0
HFD2_k127_5963473_9 PFAM Peptidase M20 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 558.0
HFD2_k127_5978819_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1246.0
HFD2_k127_5978819_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.671e-222 700.0
HFD2_k127_5978819_10 Glyoxalase bleomycin resistance protein dioxygenase superfamily protein 19 - - - 0.000000000000000000000000000000000000000000000002878 178.0
HFD2_k127_5978819_11 - - - - 0.000000000000000000000000000000000000000000006896 173.0
HFD2_k127_5978819_12 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000008171 149.0
HFD2_k127_5978819_13 - - - - 0.00000000000000000000000000000000001466 141.0
HFD2_k127_5978819_15 - - - - 0.000004993 55.0
HFD2_k127_5978819_2 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00520,K21739 - 1.16.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007155 599.0
HFD2_k127_5978819_3 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 461.0
HFD2_k127_5978819_4 Periplasmic binding protein domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 454.0
HFD2_k127_5978819_5 PFAM Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 420.0
HFD2_k127_5978819_6 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 397.0
HFD2_k127_5978819_7 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004226 330.0
HFD2_k127_5978819_8 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 291.0
HFD2_k127_5978819_9 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000001394 206.0
HFD2_k127_5993145_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 453.0
HFD2_k127_5993145_1 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 432.0
HFD2_k127_5993145_2 13-prostaglandin reductase activity K00344,K07119 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 401.0
HFD2_k127_5993145_3 Sigma-70, region 4 K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 291.0
HFD2_k127_5993145_4 photoreceptor activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001808 294.0
HFD2_k127_5993145_5 BON domain - - - 0.00000000000000000000000000000000000000000000000000000001871 204.0
HFD2_k127_5993145_6 signal transduction histidine kinase - - - 0.000000000000000000000009775 106.0
HFD2_k127_6005393_0 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0016672,GO:0016675,GO:0019538,GO:0030091,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0043546,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0055114,GO:0071704,GO:0097159,GO:1901363,GO:1901530,GO:1901564,GO:1901700 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 432.0
HFD2_k127_6005393_1 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009223 279.0
HFD2_k127_6005393_2 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000005541 198.0
HFD2_k127_6005393_3 PHP domain protein K07053 - 3.1.3.97 0.000001828 51.0
HFD2_k127_6008192_0 Sodium:solute symporter family - - - 1.067e-276 861.0
HFD2_k127_6008192_1 CoA-binding domain - - - 5.883e-212 666.0
HFD2_k127_6008192_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 399.0
HFD2_k127_6008192_3 Phosphoribosyl transferase domain K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 334.0
HFD2_k127_6008192_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000007096 262.0
HFD2_k127_6008192_5 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000009714 153.0
HFD2_k127_6008192_6 Putative nucleotide-binding of sugar-metabolising enzyme K22129 - 2.7.1.219,2.7.1.220 0.0000000000000000000001874 109.0
HFD2_k127_6025048_0 Glycosyl hydrolases family 39 K01198 - 3.2.1.37 2.771e-242 759.0
HFD2_k127_6025048_1 COG3119 Arylsulfatase A K01138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 518.0
HFD2_k127_6025048_2 Acetyl xylan esterase (AXE1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 529.0
HFD2_k127_6025048_3 PFAM glycoside hydrolase, family 29 K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 494.0
HFD2_k127_6025048_4 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 352.0
HFD2_k127_6025048_5 enterobactin catabolic process K00700,K07214,K16147 - 2.4.1.18,2.4.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 353.0
HFD2_k127_6025048_6 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000008033 283.0
HFD2_k127_6025048_7 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000000000000000000006705 228.0
HFD2_k127_6025048_8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000000000000000000000001967 178.0
HFD2_k127_6033657_0 TIGRFAM ATPase, FliI YscN family K02412 - 3.6.3.14 1.885e-203 642.0
HFD2_k127_6033657_1 The M ring may be actively involved in energy transduction K02409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 541.0
HFD2_k127_6033657_10 flagellar basal-body rod protein FlgC K02388 - - 0.00000000000000000000000000000000000000000000000000000000003722 210.0
HFD2_k127_6033657_11 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.0000000000000000000000000000000000000000000000000000000004071 221.0
HFD2_k127_6033657_12 DinB family - - - 0.00000000000000000000000000000000000000000000000138 197.0
HFD2_k127_6033657_13 Flagellar assembly protein FliH K02411 - - 0.0000000000000000000000000000000000000000000003213 175.0
HFD2_k127_6033657_14 Flagellar hook-associated protein 2 N-terminus - - - 0.0000000000000000000000000000000000000000000008783 182.0
HFD2_k127_6033657_15 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.0000000000000000000000000000000000000000001823 162.0
HFD2_k127_6033657_16 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.000000000000000000000000000000000002182 142.0
HFD2_k127_6033657_17 - - - - 0.0000000000000000000000000000000005772 147.0
HFD2_k127_6033657_18 Histidine kinase - - - 0.000000000000000000001243 100.0
HFD2_k127_6033657_2 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 480.0
HFD2_k127_6033657_20 PFAM flagellar FlbD family protein K02385 - - 0.0000000000000000001343 90.0
HFD2_k127_6033657_21 Flagellar hook-basal body complex protein FliE K02408 - - 0.000000000000000001782 88.0
HFD2_k127_6033657_22 CopG antitoxin of type II toxin-antitoxin system - - - 0.000000000000002393 78.0
HFD2_k127_6033657_23 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000001339 76.0
HFD2_k127_6033657_24 enterobactin catabolic process K07214 - - 0.00000000006087 70.0
HFD2_k127_6033657_25 Global regulator protein family K03563 - - 0.000001604 54.0
HFD2_k127_6033657_26 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000051 49.0
HFD2_k127_6033657_3 Putative glucoamylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 475.0
HFD2_k127_6033657_4 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 457.0
HFD2_k127_6033657_5 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 441.0
HFD2_k127_6033657_6 polygalacturonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 428.0
HFD2_k127_6033657_7 flagellar motor switch protein FliG K02410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 346.0
HFD2_k127_6033657_8 PFAM MotA TolQ ExbB proton channel K02556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006792 327.0
HFD2_k127_6033657_9 PFAM OmpA K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007772 267.0
HFD2_k127_6033731_0 Aconitase family (aconitate hydratase) - - - 0.0 1195.0
HFD2_k127_6033731_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 1.736e-315 979.0
HFD2_k127_6033731_10 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 617.0
HFD2_k127_6033731_11 virulence factor MVIN family protein K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 609.0
HFD2_k127_6033731_12 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 578.0
HFD2_k127_6033731_13 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 560.0
HFD2_k127_6033731_14 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 548.0
HFD2_k127_6033731_15 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 499.0
HFD2_k127_6033731_16 Thiamine pyrophosphate enzyme, central domain K01576 - 4.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 507.0
HFD2_k127_6033731_17 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 481.0
HFD2_k127_6033731_18 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005477 479.0
HFD2_k127_6033731_19 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 453.0
HFD2_k127_6033731_2 Belongs to the IlvD Edd family - - - 3.705e-287 891.0
HFD2_k127_6033731_20 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 430.0
HFD2_k127_6033731_21 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000804 421.0
HFD2_k127_6033731_22 LssY C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 426.0
HFD2_k127_6033731_23 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 437.0
HFD2_k127_6033731_24 Phosphomethylpyrimidine kinase K00882 - 2.7.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 403.0
HFD2_k127_6033731_25 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 398.0
HFD2_k127_6033731_26 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 394.0
HFD2_k127_6033731_27 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 392.0
HFD2_k127_6033731_28 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007248 383.0
HFD2_k127_6033731_29 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007883 334.0
HFD2_k127_6033731_3 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 7.12e-251 793.0
HFD2_k127_6033731_30 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 324.0
HFD2_k127_6033731_31 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 331.0
HFD2_k127_6033731_32 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 314.0
HFD2_k127_6033731_33 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 296.0
HFD2_k127_6033731_34 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006791 303.0
HFD2_k127_6033731_35 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 293.0
HFD2_k127_6033731_36 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 308.0
HFD2_k127_6033731_37 oxidation-reduction process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008879 284.0
HFD2_k127_6033731_38 IrrE N-terminal-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000244 278.0
HFD2_k127_6033731_39 acyl-coa hydrolase K01073 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 3.1.2.20 0.00000000000000000000000000000000000000000000000000000000000004394 222.0
HFD2_k127_6033731_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 5.71e-234 735.0
HFD2_k127_6033731_40 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.00000000000000000000000000000000000000000000000000000000000005151 225.0
HFD2_k127_6033731_41 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000004102 220.0
HFD2_k127_6033731_42 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000005447 211.0
HFD2_k127_6033731_43 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000000001062 208.0
HFD2_k127_6033731_44 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.0000000000000000000000000000000000000000000000000000000002326 210.0
HFD2_k127_6033731_45 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000156 206.0
HFD2_k127_6033731_46 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000625 189.0
HFD2_k127_6033731_47 Hfq protein - - - 0.000000000000000000000000000000000000000000000002313 174.0
HFD2_k127_6033731_48 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.0000000000000000000000000000000000000000007143 162.0
HFD2_k127_6033731_5 Psort location CytoplasmicMembrane, score - - - 9.99e-226 717.0
HFD2_k127_6033731_51 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000004829 151.0
HFD2_k127_6033731_52 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.0000000000000000000000000000000000000006874 153.0
HFD2_k127_6033731_53 - - - - 0.00000000000000000000000000000000004595 139.0
HFD2_k127_6033731_54 - - - - 0.0000000000000000000000000000000005351 149.0
HFD2_k127_6033731_55 - - - - 0.0000000000000000000000000001643 118.0
HFD2_k127_6033731_56 Protein of unknown function (DUF433) - - - 0.0000000000000000000000002507 116.0
HFD2_k127_6033731_57 Domain of unknown function (DUF4411) - - - 0.0000000000000000000000004558 110.0
HFD2_k127_6033731_58 membrane K00860,K00956 - 2.7.1.25,2.7.7.4 0.000000000000000000000009769 102.0
HFD2_k127_6033731_59 - - - - 0.0000000000000000000001286 103.0
HFD2_k127_6033731_6 Psort location CytoplasmicMembrane, score - - - 1.359e-217 696.0
HFD2_k127_6033731_60 oxygen carrier activity K07216 - - 0.00000000000000000005285 106.0
HFD2_k127_6033731_61 6-phosphogluconolactonase activity - - - 0.000000000000000007071 97.0
HFD2_k127_6033731_62 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000001656 96.0
HFD2_k127_6033731_64 - - - - 0.000000000000003283 78.0
HFD2_k127_6033731_66 Amidohydrolase K10220 - 4.2.1.83 0.00002995 55.0
HFD2_k127_6033731_67 DNA-templated transcription, initiation - - - 0.0002845 44.0
HFD2_k127_6033731_7 Tetratricopeptide repeat - - - 1.617e-209 675.0
HFD2_k127_6033731_8 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 1.217e-201 632.0
HFD2_k127_6033731_9 Oxidoreductase family, NAD-binding Rossmann fold - - - 3.274e-194 616.0
HFD2_k127_6071624_0 glutamate synthase alpha subunit K00265 - 1.4.1.13,1.4.1.14 0.0 2531.0
HFD2_k127_6071624_1 Succinyl-CoA ligase like flavodoxin domain K09181 - - 0.0 1442.0
HFD2_k127_6071624_11 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.000000008589 59.0
HFD2_k127_6071624_12 Domain of unknown function (DUF1858) - - - 0.0007961 48.0
HFD2_k127_6071624_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1174.0
HFD2_k127_6071624_3 nitrite transmembrane transporter activity - - - 7.132e-308 959.0
HFD2_k127_6071624_4 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 395.0
HFD2_k127_6071624_5 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 356.0
HFD2_k127_6071624_6 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000003378 245.0
HFD2_k127_6071624_7 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000007992 229.0
HFD2_k127_6071624_8 Haem-degrading - - - 0.00000000000000000000000000000000000000003559 166.0
HFD2_k127_6071624_9 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.000000000000003954 85.0
HFD2_k127_6089821_0 COG4584 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 498.0
HFD2_k127_6089821_1 Bacterial dnaA protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 368.0
HFD2_k127_6089821_2 PFAM Integrase catalytic - - - 0.00000000000000000000000000000004077 132.0
HFD2_k127_6089821_3 COG0515 Serine threonine protein K12132 - 2.7.11.1 0.000000000000002759 83.0
HFD2_k127_6089821_4 Protein kinase domain K12132 - 2.7.11.1 0.0008002 42.0
HFD2_k127_6115708_0 membrane organization K07277,K09800 - - 0.0 1495.0
HFD2_k127_6115708_1 TonB-dependent Receptor Plug Domain - - - 0.0 1429.0
HFD2_k127_6115708_10 Membrane-bound dehydrogenase domain - - - 2.869e-200 659.0
HFD2_k127_6115708_11 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009443 501.0
HFD2_k127_6115708_12 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 466.0
HFD2_k127_6115708_13 L-seryl-tRNASec selenium transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 430.0
HFD2_k127_6115708_14 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 390.0
HFD2_k127_6115708_15 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 371.0
HFD2_k127_6115708_16 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 379.0
HFD2_k127_6115708_17 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 376.0
HFD2_k127_6115708_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 349.0
HFD2_k127_6115708_19 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 342.0
HFD2_k127_6115708_2 Maltogenic Amylase, C-terminal domain K05343 - 3.2.1.1,5.4.99.16 0.0 1388.0
HFD2_k127_6115708_20 HlyD family secretion protein K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 328.0
HFD2_k127_6115708_21 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008975 320.0
HFD2_k127_6115708_22 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 326.0
HFD2_k127_6115708_23 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 293.0
HFD2_k127_6115708_24 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004885 280.0
HFD2_k127_6115708_25 Glycosyl transferase, family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009433 275.0
HFD2_k127_6115708_26 converts alpha-aldose to the beta-anomer - - - 0.0000000000000000000000000000000000000000000000000000000000000000006744 246.0
HFD2_k127_6115708_27 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001448 237.0
HFD2_k127_6115708_28 beta-galactosidase activity - - - 0.00000000000000000000000000000000000000000000000000001116 218.0
HFD2_k127_6115708_29 - - - - 0.0000000000000000000000000000000000000000000000000005958 192.0
HFD2_k127_6115708_3 Zinc carboxypeptidase K14054 - - 0.0 1165.0
HFD2_k127_6115708_30 - - - - 0.0000000000000000000000000000000000000000001632 183.0
HFD2_k127_6115708_31 - - - - 0.00000000000000000000000000000000000000001042 174.0
HFD2_k127_6115708_32 Peptidoglycan-binding domain 1 protein K07260 - 3.4.17.14 0.000000000000000000000000004451 119.0
HFD2_k127_6115708_33 Tetratricopeptide repeat - - - 0.000000000000000000000003769 119.0
HFD2_k127_6115708_34 translation initiation factor activity K09386 - - 0.00000000000000001517 98.0
HFD2_k127_6115708_35 PFAM Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000411 96.0
HFD2_k127_6115708_36 - - - - 0.0000000000000005244 81.0
HFD2_k127_6115708_37 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000003509 79.0
HFD2_k127_6115708_38 Galactose oxidase, central domain - - - 0.0000000002722 74.0
HFD2_k127_6115708_4 beta-galactosidase activity K12308 - 3.2.1.23 0.0 1140.0
HFD2_k127_6115708_40 Tetratricopeptide repeat - - - 0.0000000749 66.0
HFD2_k127_6115708_5 transport - - - 1.682e-264 852.0
HFD2_k127_6115708_6 lyase activity - - - 2.321e-229 751.0
HFD2_k127_6115708_7 FAD linked oxidase - - - 7.464e-227 709.0
HFD2_k127_6115708_8 nuclear chromosome segregation K08282 - 2.7.11.1 2.421e-215 720.0
HFD2_k127_6115708_9 Carboxypeptidase regulatory-like domain - - - 8.204e-209 688.0
HFD2_k127_6136167_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 8.122e-216 699.0
HFD2_k127_6136167_1 beta-galactosidase activity - - - 1.31e-202 639.0
HFD2_k127_6136167_10 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.0000000000000000000000000000000000006483 149.0
HFD2_k127_6136167_11 ribonuclease activity - - - 0.00000000000000000000001566 105.0
HFD2_k127_6136167_12 - - - - 0.0000000002502 65.0
HFD2_k127_6136167_13 Hypothetical glycosyl hydrolase 6 - - - 0.00001306 59.0
HFD2_k127_6136167_14 DNA integration - - - 0.0002559 46.0
HFD2_k127_6136167_15 Protein of unknown function (DUF433) - - - 0.0004509 46.0
HFD2_k127_6136167_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 578.0
HFD2_k127_6136167_3 associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 502.0
HFD2_k127_6136167_4 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 436.0
HFD2_k127_6136167_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 405.0
HFD2_k127_6136167_6 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 367.0
HFD2_k127_6136167_7 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 333.0
HFD2_k127_6136167_8 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000005778 187.0
HFD2_k127_6136167_9 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000001879 171.0
HFD2_k127_6147097_0 Permease, YjgP YjgQ - - - 6.455e-277 879.0
HFD2_k127_6147097_1 PFAM peptidase U62 modulator of DNA gyrase - - - 8.768e-254 795.0
HFD2_k127_6147097_10 ADP binding K10407 - - 0.0000000000000000000000008516 110.0
HFD2_k127_6147097_11 amine dehydrogenase activity - - - 0.000000000000167 81.0
HFD2_k127_6147097_2 Carboxypeptidase regulatory-like domain - - - 6.291e-219 703.0
HFD2_k127_6147097_3 Putative modulator of DNA gyrase - - - 1.863e-202 649.0
HFD2_k127_6147097_4 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 593.0
HFD2_k127_6147097_5 domain, Protein K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 573.0
HFD2_k127_6147097_6 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 535.0
HFD2_k127_6147097_7 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 427.0
HFD2_k127_6147097_8 response regulator K02479,K07684,K07685 - - 0.000000000000000000000000000000000000000000000000000000000000001418 226.0
HFD2_k127_6147097_9 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000000569 147.0
HFD2_k127_6166651_0 Cytochrome c - - - 0.0 1051.0
HFD2_k127_6166651_1 Protein of unknown function (DUF1501) - - - 1.472e-250 779.0
HFD2_k127_6166651_2 PFAM glycoside hydrolase family 39 K01198 - 3.2.1.37 1.222e-202 640.0
HFD2_k127_6166651_3 serine-type peptidase activity - - - 1.734e-197 636.0
HFD2_k127_6166651_4 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 577.0
HFD2_k127_6166651_6 Amidohydrolase K07045 - - 0.0000000000000000000000000000004525 132.0
HFD2_k127_6166651_7 Integrase core domain - - - 0.000000000004606 71.0
HFD2_k127_6166651_8 FecR protein - - - 0.0001194 54.0
HFD2_k127_6166651_9 COG0457 FOG TPR repeat - - - 0.0006375 52.0
HFD2_k127_616864_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1349.0
HFD2_k127_616864_1 Peptidase dimerisation domain K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 538.0
HFD2_k127_616864_2 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 460.0
HFD2_k127_616864_3 tRNA processing K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 444.0
HFD2_k127_616864_4 Thermolysin metallopeptidase, alpha-helical domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 465.0
HFD2_k127_616864_5 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009801 395.0
HFD2_k127_616864_6 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007238 346.0
HFD2_k127_616864_7 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 312.0
HFD2_k127_616864_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002754 235.0
HFD2_k127_616864_9 - - - - 0.000000003151 61.0
HFD2_k127_6207256_0 Rhodopirellula transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 507.0
HFD2_k127_6207256_1 MULE transposase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 317.0
HFD2_k127_6207256_2 SPTR Transposase IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001443 250.0
HFD2_k127_6207256_3 Transposase, Mutator family - - - 0.0000000000000000000000000000000000000000000000000000000000002282 216.0
HFD2_k127_6207256_4 Putative ATPase subunit of terminase (gpP-like) - - - 0.00004089 51.0
HFD2_k127_6232623_0 Right handed beta helix region - - - 3.03e-264 827.0
HFD2_k127_6232623_1 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 464.0
HFD2_k127_6232623_2 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 411.0
HFD2_k127_6232623_3 - - - - 0.00000000000000000000000000000000000000000001736 177.0
HFD2_k127_6232623_4 Inositol monophosphatase K01092,K05602,K18649 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008934,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016020,GO:0016053,GO:0016137,GO:0016138,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052745,GO:0052803,GO:0052834,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659 3.1.3.15,3.1.3.25,3.1.3.93 0.000000000000000000000000000001879 123.0
HFD2_k127_6265247_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 1.132e-228 716.0
HFD2_k127_6265247_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 616.0
HFD2_k127_6265247_10 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 334.0
HFD2_k127_6265247_11 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 312.0
HFD2_k127_6265247_12 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004683 280.0
HFD2_k127_6265247_13 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001698 258.0
HFD2_k127_6265247_14 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000004621 122.0
HFD2_k127_6265247_15 - - - - 0.00000000000000000000005169 101.0
HFD2_k127_6265247_16 - - - - 0.0000000000000000000002155 106.0
HFD2_k127_6265247_17 Two component signalling adaptor domain - - - 0.0000000000003716 77.0
HFD2_k127_6265247_18 collagen metabolic process K08677 - - 0.00000003594 66.0
HFD2_k127_6265247_2 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 597.0
HFD2_k127_6265247_3 Two component signalling adaptor domain K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007042 536.0
HFD2_k127_6265247_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K19969 - 4.2.3.152,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 479.0
HFD2_k127_6265247_5 hydrolase activity, acting on ester bonds K07051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 436.0
HFD2_k127_6265247_6 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 430.0
HFD2_k127_6265247_7 chemotaxis protein methyltransferase K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 430.0
HFD2_k127_6265247_8 PFAM histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 424.0
HFD2_k127_6265247_9 PFAM Prenyltransferase squalene oxidase K01077,K11751 - 3.1.3.1,3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 411.0
HFD2_k127_6270947_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 525.0
HFD2_k127_6270947_1 Domain of unknown function (DUF3488) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 388.0
HFD2_k127_6270947_2 PFAM FG-GAP repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 397.0
HFD2_k127_6270947_3 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000000005708 176.0
HFD2_k127_6270947_4 Gaf domain K08968 - 1.8.4.14 0.00000000000000000000000000000000000006826 160.0
HFD2_k127_6270947_5 TadE-like protein - - - 0.00000000000000000000000000000003632 136.0
HFD2_k127_6270947_6 PFAM TadE family protein - - - 0.0000000000000000000000000003858 119.0
HFD2_k127_6304585_0 PFAM glycosyl transferase, family 51 K05365 - 2.4.1.129,3.4.16.4 0.0 1105.0
HFD2_k127_6304585_1 Carboxypeptidase regulatory-like domain - - - 1.056e-247 808.0
HFD2_k127_6304585_10 - - - - 0.0000000000000000000000000000000000000000006015 162.0
HFD2_k127_6304585_13 Tetratricopeptide repeat - - - 0.0000000000000000000000003436 118.0
HFD2_k127_6304585_14 Methyltransferase FkbM domain - - - 0.00000000000000000000003896 110.0
HFD2_k127_6304585_15 Leucine-rich repeat - - - 0.000000000000009433 87.0
HFD2_k127_6304585_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009875 523.0
HFD2_k127_6304585_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 501.0
HFD2_k127_6304585_4 PFAM Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 428.0
HFD2_k127_6304585_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 306.0
HFD2_k127_6304585_6 CBD_II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008844 305.0
HFD2_k127_6304585_7 Leucine-rich repeats, outliers - - - 0.0000000000000000000000000000000000000000000000000000001525 218.0
HFD2_k127_6304585_8 - - - - 0.0000000000000000000000000000000000000000000000000009488 188.0
HFD2_k127_6304585_9 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000003326 192.0
HFD2_k127_63276_0 Carboxypeptidase regulatory-like domain - - - 0.0 1210.0
HFD2_k127_63276_1 Carboxypeptidase regulatory-like domain - - - 1.143e-276 889.0
HFD2_k127_63276_10 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 419.0
HFD2_k127_63276_11 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 404.0
HFD2_k127_63276_12 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 342.0
HFD2_k127_63276_13 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002105 287.0
HFD2_k127_63276_14 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001425 272.0
HFD2_k127_63276_15 PFAM oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000005219 246.0
HFD2_k127_63276_16 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003133 233.0
HFD2_k127_63276_17 Belongs to the glycosyl hydrolase 32 family K01119 - 3.1.3.6,3.1.4.16 0.000000000000000000000000000000000000000000000000000000000000001804 241.0
HFD2_k127_63276_18 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000808 222.0
HFD2_k127_63276_19 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01639,K01714 - 4.1.3.3,4.3.3.7 0.0000000000000000000000000000000000000000000000000000006582 203.0
HFD2_k127_63276_2 WD40 domain protein beta Propeller K12132 - 2.7.11.1 3.614e-210 681.0
HFD2_k127_63276_20 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000008874 212.0
HFD2_k127_63276_21 Sodium:solute symporter family - - - 0.0000000000000000000000000000000000000000000000000001639 205.0
HFD2_k127_63276_22 FG-GAP repeat protein - - - 0.0000000000000000000000000000000000000000000000000009445 209.0
HFD2_k127_63276_23 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000001533 194.0
HFD2_k127_63276_24 Transcriptional regulator IclR - - - 0.0000000000000000000000000000000000000000000000002277 186.0
HFD2_k127_63276_25 - - - - 0.00000000000000000000000000000000000000000006925 173.0
HFD2_k127_63276_26 Integrase - - - 0.000000000000000000000000000000002337 131.0
HFD2_k127_63276_27 Belongs to the glycosyl hydrolase 67 family K01235 - 3.2.1.139 0.00000000000000000000000002937 126.0
HFD2_k127_63276_28 PFAM Formylglycine-generating sulfatase enzyme K13444 - 1.8.3.7 0.00000000000000000746 99.0
HFD2_k127_63276_29 ubiE/COQ5 methyltransferase family - - - 0.00000000000000751 86.0
HFD2_k127_63276_3 WD40 domain protein beta Propeller K12132 - 2.7.11.1 5.256e-205 666.0
HFD2_k127_63276_30 Calcineurin-like phosphoesterase K01190 - 3.2.1.23 0.0000000001012 73.0
HFD2_k127_63276_31 self proteolysis K11021 - - 0.000000001432 63.0
HFD2_k127_63276_32 self proteolysis K11021 - - 0.0000005097 53.0
HFD2_k127_63276_33 PFAM NHL repeat containing protein K13735 - - 0.00001335 59.0
HFD2_k127_63276_34 Integrase core domain - - - 0.00002975 49.0
HFD2_k127_63276_35 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.00008658 49.0
HFD2_k127_63276_4 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 3.34e-200 627.0
HFD2_k127_63276_5 transmembrane transporter activity K08194 - - 1.119e-198 627.0
HFD2_k127_63276_6 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 542.0
HFD2_k127_63276_7 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 477.0
HFD2_k127_63276_8 methyltransferase K09846,K16034,K20421 - 2.1.1.210,2.1.1.303 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 440.0
HFD2_k127_63276_9 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 432.0
HFD2_k127_6330774_0 Carboxypeptidase regulatory-like domain - - - 9.332e-278 887.0
HFD2_k127_6330774_1 hydrolase activity, hydrolyzing O-glycosyl compounds K12373 - 3.2.1.52 3.243e-275 865.0
HFD2_k127_6330774_10 pathogenesis K01460 - 3.5.1.78,6.3.1.8 0.00000000000000000000002891 111.0
HFD2_k127_6330774_11 Belongs to the 'phage' integrase family - - - 0.0000000000323 74.0
HFD2_k127_6330774_12 PFAM Xylose isomerase - - - 0.00003285 55.0
HFD2_k127_6330774_2 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 593.0
HFD2_k127_6330774_3 PKD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 463.0
HFD2_k127_6330774_4 Oxidoreductase family, C-terminal alpha beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 330.0
HFD2_k127_6330774_5 PFAM oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004735 267.0
HFD2_k127_6330774_6 DinB family - - - 0.0000000000000000000000000000000000000000000000000000000000000001593 226.0
HFD2_k127_6330774_7 Aminotransferase, class V - - - 0.000000000000000000000000000000000000000000000000000000000000001076 234.0
HFD2_k127_6330774_8 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000001993 168.0
HFD2_k127_6330774_9 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000182 147.0
HFD2_k127_6358247_0 Carboxypeptidase regulatory-like domain - - - 0.0 1119.0
HFD2_k127_6358247_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 2.485e-281 871.0
HFD2_k127_6358247_10 CoA binding domain K06929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000001094 131.0
HFD2_k127_6358247_11 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000008043 106.0
HFD2_k127_6358247_2 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 565.0
HFD2_k127_6358247_3 Major Facilitator Superfamily K03535 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 534.0
HFD2_k127_6358247_4 metal ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009117 521.0
HFD2_k127_6358247_5 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002249 256.0
HFD2_k127_6358247_6 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000006911 234.0
HFD2_k127_6358247_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000515 220.0
HFD2_k127_6358247_8 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000001477 198.0
HFD2_k127_6358247_9 - - - - 0.00000000000000000000000000000000000000000001029 179.0
HFD2_k127_6386686_0 - - - - 0.0 1014.0
HFD2_k127_6386686_1 TonB-dependent receptor - - - 2.369e-248 799.0
HFD2_k127_6386686_10 TIR domain K12132 - 2.7.11.1 0.0000000000000000000000549 113.0
HFD2_k127_6386686_11 glycosyl transferase family 2 K20444 - - 0.0000000000000000324 95.0
HFD2_k127_6386686_12 PFAM Nickel transport complex, NikM subunit, transmembrane K16915 - - 0.0000000000000001057 83.0
HFD2_k127_6386686_13 HD domain - - - 0.0000000000000001769 91.0
HFD2_k127_6386686_14 - - - - 0.000000000000000193 92.0
HFD2_k127_6386686_15 Band 7 protein - - - 0.0000000000119 78.0
HFD2_k127_6386686_16 HEAT repeats - - - 0.0000000000282 76.0
HFD2_k127_6386686_2 PFAM oxidoreductase domain protein - - - 2.471e-206 649.0
HFD2_k127_6386686_3 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007315 547.0
HFD2_k127_6386686_4 Protein of unknown function (DUF3738) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004152 470.0
HFD2_k127_6386686_5 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 383.0
HFD2_k127_6386686_6 metal cluster binding K06940 - - 0.000000000000000000000000000000000000000000000000000000004698 202.0
HFD2_k127_6386686_7 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000000000000000000001028 183.0
HFD2_k127_6386686_8 Aminoacyl-tRNA editing domain K19055 - - 0.00000000000000000000000000000000000000000000000005197 182.0
HFD2_k127_6386686_9 TonB-dependent receptor - - - 0.0000000000000000000000000000000311 134.0
HFD2_k127_6392858_0 AcrB/AcrD/AcrF family - - - 0.0 1596.0
HFD2_k127_6392858_1 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 6.061e-282 895.0
HFD2_k127_6392858_10 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000002991 235.0
HFD2_k127_6392858_11 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000003446 170.0
HFD2_k127_6392858_12 Protein of unknown function (DUF3592) - - - 0.00000000000000000000000000000000000000001003 174.0
HFD2_k127_6392858_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000004397 150.0
HFD2_k127_6392858_14 Histidine kinase - - - 0.00000000000000000000000000000001396 142.0
HFD2_k127_6392858_15 Protein of unknown function (DUF2892) - - - 0.0000000000000000000001149 102.0
HFD2_k127_6392858_16 Putative zinc-finger - - - 0.0000000001388 65.0
HFD2_k127_6392858_17 - - - - 0.000000151 63.0
HFD2_k127_6392858_18 DoxX-like family - - - 0.00001179 52.0
HFD2_k127_6392858_2 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 592.0
HFD2_k127_6392858_3 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 520.0
HFD2_k127_6392858_4 Belongs to the peptidase S8 family K14647 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000837 536.0
HFD2_k127_6392858_5 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 511.0
HFD2_k127_6392858_6 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 418.0
HFD2_k127_6392858_7 two component, sigma54 specific, transcriptional regulator, Fis family K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 407.0
HFD2_k127_6392858_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008114 325.0
HFD2_k127_6392858_9 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005167 252.0
HFD2_k127_6393935_0 Peptidase C39 family K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 617.0
HFD2_k127_6393935_1 ABC transporter, ATP-binding protein K06147 - - 0.000000000000000000000000000000000000000000000000653 184.0
HFD2_k127_6398218_0 PFAM peptidase K01284,K01414 - 3.4.15.5,3.4.24.70 3.5e-323 1000.0
HFD2_k127_6398218_1 CAAX protease self-immunity K07052 - - 1e-322 1021.0
HFD2_k127_6398218_10 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 301.0
HFD2_k127_6398218_11 type II secretion system K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000308 278.0
HFD2_k127_6398218_12 type II secretion system K12510 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003043 269.0
HFD2_k127_6398218_13 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000001015 204.0
HFD2_k127_6398218_14 proteolysis - - - 0.000000000000000000000000000000000000000000000000000000005743 220.0
HFD2_k127_6398218_15 2'-5' RNA ligase superfamily - - - 0.000000000000000000000000000000000000000000000000004987 186.0
HFD2_k127_6398218_16 response regulator K02479,K07684,K07685 - - 0.000000000000000000000000000000000000000000000000005138 188.0
HFD2_k127_6398218_17 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594 - 1.16.3.1 0.0000000000000000000000000000000000000007284 154.0
HFD2_k127_6398218_18 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000008063 154.0
HFD2_k127_6398218_2 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 2.475e-253 816.0
HFD2_k127_6398218_20 periplasmic or secreted lipoprotein - - - 0.00000000000000000000000009864 118.0
HFD2_k127_6398218_21 Putative Flp pilus-assembly TadE/G-like - - - 0.000000000000000000000005084 118.0
HFD2_k127_6398218_22 PFAM TadE family protein K02282 - - 0.0000000000000000000003958 102.0
HFD2_k127_6398218_23 - - - - 0.000000000000000000005536 96.0
HFD2_k127_6398218_24 AraC-like ligand binding domain - - - 0.00000000000002828 72.0
HFD2_k127_6398218_3 PFAM type II secretion system protein E K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009848 571.0
HFD2_k127_6398218_4 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 563.0
HFD2_k127_6398218_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 476.0
HFD2_k127_6398218_6 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 383.0
HFD2_k127_6398218_7 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008814 328.0
HFD2_k127_6398218_8 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 322.0
HFD2_k127_6398218_9 AAA domain K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 315.0
HFD2_k127_6402258_0 WD domain, G-beta repeat - - - 9.798e-202 675.0
HFD2_k127_6402258_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 8.241e-198 633.0
HFD2_k127_6402258_10 TIR domain - - - 0.000000000000000000000000000000000000009645 169.0
HFD2_k127_6402258_11 chorismate mutase - - - 0.000000000000000000000000000643 119.0
HFD2_k127_6402258_12 - - - - 0.0000000001656 70.0
HFD2_k127_6402258_2 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 472.0
HFD2_k127_6402258_3 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 463.0
HFD2_k127_6402258_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 407.0
HFD2_k127_6402258_5 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 332.0
HFD2_k127_6402258_6 PFAM Prephenate dehydrogenase K00210,K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 327.0
HFD2_k127_6402258_7 cobalamin-transporting ATPase activity K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 290.0
HFD2_k127_6402258_8 PFAM Prenyltransferase squalene oxidase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000211 233.0
HFD2_k127_6402258_9 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000001427 210.0
HFD2_k127_6402916_0 Carboxypeptidase regulatory-like domain - - - 6.092e-265 835.0
HFD2_k127_6402916_1 siderophore transport K02014 - - 1.877e-223 721.0
HFD2_k127_6402916_2 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 379.0
HFD2_k127_6402916_3 helix_turn_helix gluconate operon transcriptional repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 334.0
HFD2_k127_6419706_0 Carboxypeptidase regulatory-like domain - - - 0.0 1065.0
HFD2_k127_6419706_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 563.0
HFD2_k127_6419706_10 Tricorn protease homolog K08676 - - 0.000000005303 58.0
HFD2_k127_6419706_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 538.0
HFD2_k127_6419706_3 Zinc-uptake complex component A periplasmic K02077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 482.0
HFD2_k127_6419706_4 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 453.0
HFD2_k127_6419706_5 Glycosyl hydrolases family 2 K01190 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 428.0
HFD2_k127_6419706_6 Tricorn protease homolog K08676 - - 0.000000000000000000000000000000000000000000000000000000000000000001748 240.0
HFD2_k127_6419706_7 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000001267 162.0
HFD2_k127_6419706_8 Tricorn protease PDZ domain K08676 - - 0.0000000000000000000000000000000000000008321 152.0
HFD2_k127_6419706_9 - - - - 0.000000000000000000000000000000000001722 138.0
HFD2_k127_6422285_0 FecR protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 530.0
HFD2_k127_6422285_1 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 309.0
HFD2_k127_6422285_2 Glycosyltransferase Family 4 - - - 0.00000000003083 65.0
HFD2_k127_6460063_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005893 441.0
HFD2_k127_6460063_1 resolvase - - - 0.00000000000000000002005 91.0
HFD2_k127_6469487_0 MULE transposase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002836 241.0
HFD2_k127_6469487_1 Putative transposase of IS4/5 family (DUF4096) - - - 0.0000000000000000000000000000000000000000000000000000000002807 204.0
HFD2_k127_6469487_2 Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000002924 185.0
HFD2_k127_6469487_3 MULE transposase domain - - - 0.00000000000000000000000000000000000000002483 158.0
HFD2_k127_6469487_4 Integrase core domain - - - 0.00000000000000000000000000000000000000007662 154.0
HFD2_k127_6469487_5 - - - - 0.000000000000000000000000000000000000001414 157.0
HFD2_k127_6469487_6 - - - - 0.000000002996 64.0
HFD2_k127_6469487_7 Transposase and inactivated derivatives - - - 0.00002609 49.0
HFD2_k127_6469564_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 2.552e-308 976.0
HFD2_k127_6469564_1 Belongs to the peptidase S8 family - - - 5.505e-240 778.0
HFD2_k127_6469564_10 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 432.0
HFD2_k127_6469564_11 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 398.0
HFD2_k127_6469564_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 367.0
HFD2_k127_6469564_13 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 366.0
HFD2_k127_6469564_14 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 355.0
HFD2_k127_6469564_15 Nitrile hydratase, alpha chain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 327.0
HFD2_k127_6469564_16 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 335.0
HFD2_k127_6469564_17 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 289.0
HFD2_k127_6469564_18 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002215 270.0
HFD2_k127_6469564_19 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.0000000000000000000000000000000000000000000000000000000000000000000000000001789 263.0
HFD2_k127_6469564_2 PFAM amidohydrolase - - - 3.481e-219 729.0
HFD2_k127_6469564_20 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000001825 264.0
HFD2_k127_6469564_21 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001301 256.0
HFD2_k127_6469564_22 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000001201 188.0
HFD2_k127_6469564_23 Nitrile hydratase beta subunit - - - 0.000000000000000000000000000000000001686 148.0
HFD2_k127_6469564_24 PFAM Cupin 2 conserved barrel domain protein - - - 0.0000000000000000000000000000000005787 133.0
HFD2_k127_6469564_25 pathogenesis K01337,K20276,K21449 - 3.4.21.50 0.00000000000000000000000000004541 136.0
HFD2_k127_6469564_26 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000002445 119.0
HFD2_k127_6469564_27 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000009634 128.0
HFD2_k127_6469564_28 - - - - 0.0000000000000000000000004436 111.0
HFD2_k127_6469564_29 o-methyltransferase - - - 0.000000004276 61.0
HFD2_k127_6469564_3 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 645.0
HFD2_k127_6469564_4 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 619.0
HFD2_k127_6469564_5 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 581.0
HFD2_k127_6469564_6 Phosphoesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 533.0
HFD2_k127_6469564_7 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 512.0
HFD2_k127_6469564_8 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 502.0
HFD2_k127_6469564_9 N-acetylglucosaminylinositol deacetylase activity K01463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 413.0
HFD2_k127_6475366_0 cluster binding protein K18929 - - 3.771e-203 636.0
HFD2_k127_6475366_1 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 364.0
HFD2_k127_6479890_0 GntP family permease K03299 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 579.0
HFD2_k127_6479890_1 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003522 271.0
HFD2_k127_6479890_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000002379 156.0
HFD2_k127_6479890_3 DinB family - - - 0.00000000000000000000000000000000006033 140.0
HFD2_k127_6506920_0 Carboxypeptidase regulatory-like domain - - - 2.067e-232 740.0
HFD2_k127_6547499_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1195.0
HFD2_k127_6547499_1 transport - - - 0.0 1133.0
HFD2_k127_6547499_10 Membrane-bound dehydrogenase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007393 498.0
HFD2_k127_6547499_11 Major facilitator superfamily K02429 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 411.0
HFD2_k127_6547499_12 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 401.0
HFD2_k127_6547499_13 COGs COG0673 dehydrogenase and related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 409.0
HFD2_k127_6547499_14 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 396.0
HFD2_k127_6547499_15 Domain of unknown function (DUF4091) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006796 336.0
HFD2_k127_6547499_16 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 327.0
HFD2_k127_6547499_17 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 313.0
HFD2_k127_6547499_18 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006136 292.0
HFD2_k127_6547499_19 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 288.0
HFD2_k127_6547499_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1057.0
HFD2_k127_6547499_20 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002592 265.0
HFD2_k127_6547499_21 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000005137 259.0
HFD2_k127_6547499_22 Major facilitator superfamily MFS_1 K08191 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000913 256.0
HFD2_k127_6547499_23 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000001113 255.0
HFD2_k127_6547499_24 - - - - 0.00000000000000000000000000000000000000000000000000000000000002128 225.0
HFD2_k127_6547499_25 Belongs to the glycosyl hydrolase family 6 - - - 0.00000000000000000000000000000000000000000000001019 196.0
HFD2_k127_6547499_26 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000005021 139.0
HFD2_k127_6547499_27 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.0000000000000000000000001277 124.0
HFD2_k127_6547499_28 - K09004 - - 0.00000000000000000006483 96.0
HFD2_k127_6547499_3 BNR repeat-like domain K05989 - 3.2.1.40 2.133e-241 779.0
HFD2_k127_6547499_30 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000006317 61.0
HFD2_k127_6547499_31 - - - - 0.00000589 59.0
HFD2_k127_6547499_32 - - - - 0.00007093 47.0
HFD2_k127_6547499_4 PFAM oxidoreductase domain protein - - - 2.579e-234 729.0
HFD2_k127_6547499_5 Periplasmic copper-binding protein (NosD) K01209 - 3.2.1.55 8.744e-233 736.0
HFD2_k127_6547499_6 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 607.0
HFD2_k127_6547499_7 Domain of unknown function (DUF4962) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 575.0
HFD2_k127_6547499_8 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 543.0
HFD2_k127_6547499_9 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 499.0
HFD2_k127_6572785_0 Carboxypeptidase regulatory-like domain - - - 0.0 1034.0
HFD2_k127_6572785_1 Carboxypeptidase regulatory-like domain - - - 6.744e-264 850.0
HFD2_k127_6572785_2 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 535.0
HFD2_k127_6572785_3 Membrane-bound dehydrogenase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 381.0
HFD2_k127_6572785_5 - - - - 0.0000006973 59.0
HFD2_k127_6580553_0 Tetratricopeptide repeats - - - 5.278e-264 834.0
HFD2_k127_6580553_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 573.0
HFD2_k127_6580553_2 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 490.0
HFD2_k127_6580553_3 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000001102 96.0
HFD2_k127_6587255_0 Catalyzes the conversion of L-arabinose to L-ribulose K01804 - 5.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 440.0
HFD2_k127_6587255_1 PFAM glycoside hydrolase, family 10 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007589 288.0
HFD2_k127_6594803_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1185.0
HFD2_k127_6594803_1 cytochrome C - - - 1.668e-313 983.0
HFD2_k127_6594803_10 Putative modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 427.0
HFD2_k127_6594803_11 penicillin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 407.0
HFD2_k127_6594803_12 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 377.0
HFD2_k127_6594803_13 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 321.0
HFD2_k127_6594803_14 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001424 293.0
HFD2_k127_6594803_15 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000001387 257.0
HFD2_k127_6594803_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000009772 237.0
HFD2_k127_6594803_18 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.00000000000000000000000000000000000000000000000000005751 199.0
HFD2_k127_6594803_19 zinc D-Ala-D-Ala carboxypeptidase activity K08641 - 3.4.13.22 0.00000000000000000000000000000001684 144.0
HFD2_k127_6594803_2 Carboxypeptidase regulatory-like domain - - - 1.104e-257 845.0
HFD2_k127_6594803_20 myo-inosose-2 dehydratase activity - - - 0.0000000000000000001434 100.0
HFD2_k127_6594803_21 - - - - 0.0000006073 56.0
HFD2_k127_6594803_3 arylsulfatase activity - - - 1.13e-239 764.0
HFD2_k127_6594803_4 Protein of unknown function (DUF1501) - - - 7.92e-225 707.0
HFD2_k127_6594803_5 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 1.047e-207 664.0
HFD2_k127_6594803_6 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 548.0
HFD2_k127_6594803_7 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 485.0
HFD2_k127_6594803_8 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 446.0
HFD2_k127_6594803_9 Peptidase dimerisation domain K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007664 446.0
HFD2_k127_6653112_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1361.0
HFD2_k127_6653112_1 PQQ enzyme repeat K00117 - 1.1.5.2 8.756e-286 893.0
HFD2_k127_6653112_10 DegT/DnrJ/EryC1/StrS aminotransferase family K12452,K13017 - 1.17.1.1,2.6.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 373.0
HFD2_k127_6653112_11 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 376.0
HFD2_k127_6653112_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 368.0
HFD2_k127_6653112_13 ethanolamine catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002073 280.0
HFD2_k127_6653112_14 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000413 303.0
HFD2_k127_6653112_15 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008612 267.0
HFD2_k127_6653112_16 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000507 277.0
HFD2_k127_6653112_17 Cytidylyltransferase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000001655 235.0
HFD2_k127_6653112_18 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 - 3.5.99.2 0.00000000000000000000000000000000000000000000000000000000000000003255 233.0
HFD2_k127_6653112_19 DinB family - - - 0.00000000000000000000000000000000000000000000000000000004795 210.0
HFD2_k127_6653112_2 FAD dependent oxidoreductase - - - 2.584e-277 866.0
HFD2_k127_6653112_20 DinB superfamily - - - 0.0000000000000000000000000005258 118.0
HFD2_k127_6653112_21 Phospholipid methyltransferase - - - 0.000000000000000002344 91.0
HFD2_k127_6653112_22 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000003073 81.0
HFD2_k127_6653112_3 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.926e-250 812.0
HFD2_k127_6653112_4 electron transfer activity K03615 - - 6.011e-218 682.0
HFD2_k127_6653112_5 Involved in the tonB-independent uptake of proteins - - - 1.669e-212 688.0
HFD2_k127_6653112_6 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 449.0
HFD2_k127_6653112_7 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 454.0
HFD2_k127_6653112_8 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009698 427.0
HFD2_k127_6653112_9 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 406.0
HFD2_k127_667567_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2620.0
HFD2_k127_667567_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0 1086.0
HFD2_k127_667567_10 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 5.039e-196 619.0
HFD2_k127_667567_11 PFAM CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 575.0
HFD2_k127_667567_12 radical SAM domain protein K15045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 554.0
HFD2_k127_667567_13 PFAM PhoH family protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 544.0
HFD2_k127_667567_14 Iron-containing alcohol dehydrogenase K11173 - 1.1.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006758 563.0
HFD2_k127_667567_15 PAS fold-4 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 540.0
HFD2_k127_667567_16 lipolytic protein G-D-S-L family K05970 - 3.1.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 499.0
HFD2_k127_667567_17 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 449.0
HFD2_k127_667567_18 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 418.0
HFD2_k127_667567_19 ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008335 409.0
HFD2_k127_667567_2 Uncharacterized protein family (UPF0051) K09014 - - 6.01e-271 838.0
HFD2_k127_667567_20 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008403 419.0
HFD2_k127_667567_21 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 355.0
HFD2_k127_667567_22 deoxyhypusine monooxygenase activity K00627,K02160,K07402 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 332.0
HFD2_k127_667567_23 Belongs to the Dps family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 309.0
HFD2_k127_667567_24 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000783 264.0
HFD2_k127_667567_25 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004775 246.0
HFD2_k127_667567_26 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000002094 207.0
HFD2_k127_667567_27 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000000000000213 203.0
HFD2_k127_667567_29 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000007585 170.0
HFD2_k127_667567_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 7.635e-242 750.0
HFD2_k127_667567_30 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000001931 145.0
HFD2_k127_667567_31 Pfam:DUF59 - - - 0.00000000000000000000000000000000000002335 158.0
HFD2_k127_667567_32 Rieske-like [2Fe-2S] domain K05710 - - 0.0000000000000000000000000000002156 126.0
HFD2_k127_667567_33 Putative restriction endonuclease - - - 0.0000000000000000000000003804 105.0
HFD2_k127_667567_34 hyperosmotic response - - - 0.000000000000000276 83.0
HFD2_k127_667567_35 Redoxin K03564 - 1.11.1.15 0.000000000008294 65.0
HFD2_k127_667567_36 - - - - 0.00000001312 62.0
HFD2_k127_667567_37 PFAM Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.00000001375 63.0
HFD2_k127_667567_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 8.194e-242 767.0
HFD2_k127_667567_5 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 9.181e-236 737.0
HFD2_k127_667567_6 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 1.439e-222 722.0
HFD2_k127_667567_7 3-oxoacyl-[acyl-carrier-protein] synthase activity K06406 - - 1.04e-214 694.0
HFD2_k127_667567_8 Belongs to the xylose isomerase family K01805 - 5.3.1.5 1.353e-198 625.0
HFD2_k127_667567_9 Luciferase-like monooxygenase - - - 1.403e-196 629.0
HFD2_k127_6705422_0 Carboxypeptidase regulatory-like domain - - - 2.097e-242 788.0
HFD2_k127_6705422_1 TonB-dependent receptor - - - 6.357e-232 759.0
HFD2_k127_6705422_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005234 608.0
HFD2_k127_6705422_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000907 523.0
HFD2_k127_6705422_4 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 528.0
HFD2_k127_6705422_5 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 456.0
HFD2_k127_6705422_6 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001994 267.0
HFD2_k127_6705422_7 Thioesterase superfamily K07107 - - 0.00000000000000000000000000000000000000000004301 166.0
HFD2_k127_6720480_0 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 355.0
HFD2_k127_6720480_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000004936 83.0
HFD2_k127_677868_0 Carboxypeptidase regulatory-like domain - - - 1.61e-231 754.0
HFD2_k127_677868_1 Phosphopantetheine attachment site - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 550.0
HFD2_k127_677868_2 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499 524.0
HFD2_k127_677868_3 Methyltransferase FkbM domain - - - 0.0000000000000006705 88.0
HFD2_k127_6783709_0 PHP domain protein - - - 5.583e-268 840.0
HFD2_k127_6783709_1 Insulinase (Peptidase family M16) - - - 1.54e-199 633.0
HFD2_k127_6783709_2 Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 542.0
HFD2_k127_6783709_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07640 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 508.0
HFD2_k127_6783709_4 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 314.0
HFD2_k127_6783709_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 314.0
HFD2_k127_6783709_6 PFAM response regulator receiver K07662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 294.0
HFD2_k127_678872_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0 1802.0
HFD2_k127_678872_1 transport - - - 0.0 1452.0
HFD2_k127_678872_10 endonuclease activity - - - 0.00000000000000000000271 98.0
HFD2_k127_678872_11 Domain of unknown function (DUF4157) - - - 0.0000000000000002966 93.0
HFD2_k127_678872_13 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.00000000001984 66.0
HFD2_k127_678872_2 Amidohydrolase family - - - 6.679e-234 778.0
HFD2_k127_678872_3 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 633.0
HFD2_k127_678872_4 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009843 499.0
HFD2_k127_678872_5 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 321.0
HFD2_k127_678872_6 SnoaL-like domain - - - 0.0000000000000000000000000000000001779 142.0
HFD2_k127_678872_7 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000000000000000002284 133.0
HFD2_k127_678872_8 PFAM transcriptional regulator PadR family protein - - - 0.000000000000000000000000004576 116.0
HFD2_k127_678872_9 - - - - 0.000000000000000000001607 100.0
HFD2_k127_6804104_0 Glycosyl transferases group 1 - - - 0.0 1107.0
HFD2_k127_6804104_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01890,K06878 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.0 1038.0
HFD2_k127_6804104_10 Domain of unknown function (DUF1972) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008249 509.0
HFD2_k127_6804104_11 extracellular polysaccharide biosynthetic process K00568,K03561,K07011,K20444 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 483.0
HFD2_k127_6804104_12 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K18827 - 2.1.1.222,2.1.1.294,2.1.1.64,2.7.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009624 482.0
HFD2_k127_6804104_13 L-seryl-tRNASec selenium transferase activity K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 462.0
HFD2_k127_6804104_14 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 466.0
HFD2_k127_6804104_15 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008526 449.0
HFD2_k127_6804104_16 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 438.0
HFD2_k127_6804104_17 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 435.0
HFD2_k127_6804104_18 COG3119 Arylsulfatase A K01138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 423.0
HFD2_k127_6804104_19 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008852 381.0
HFD2_k127_6804104_2 domain, Protein K20276 - - 7.279e-314 986.0
HFD2_k127_6804104_20 Peptidase family U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 383.0
HFD2_k127_6804104_21 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 372.0
HFD2_k127_6804104_22 Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008712 348.0
HFD2_k127_6804104_23 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 335.0
HFD2_k127_6804104_24 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 325.0
HFD2_k127_6804104_25 PFAM tRNA rRNA methyltransferase, SpoU K02533 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 326.0
HFD2_k127_6804104_26 translation initiation factor activity K06370 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 338.0
HFD2_k127_6804104_27 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001136 286.0
HFD2_k127_6804104_28 DinB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005449 280.0
HFD2_k127_6804104_29 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001565 250.0
HFD2_k127_6804104_3 Wzt C-terminal domain K09691 - - 3.101e-229 715.0
HFD2_k127_6804104_30 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000002679 226.0
HFD2_k127_6804104_31 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000828 246.0
HFD2_k127_6804104_32 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000004034 204.0
HFD2_k127_6804104_33 Tyrosine phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000009841 207.0
HFD2_k127_6804104_34 PFAM HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000001898 202.0
HFD2_k127_6804104_35 COG2133 Glucose sorbosone dehydrogenases - - - 0.00000000000000000000000000000000000000000000000005361 189.0
HFD2_k127_6804104_37 Caspase domain - - - 0.000000000000000000000000000000000000000009938 175.0
HFD2_k127_6804104_39 Uncharacterized protein conserved in bacteria (DUF2141) - - - 0.0000000000000000000000001106 112.0
HFD2_k127_6804104_4 Protein of unknown function (DUF1501) - - - 4.582e-200 631.0
HFD2_k127_6804104_40 monooxygenase activity - - - 0.000000000000000000003029 96.0
HFD2_k127_6804104_41 Putative esterase - - - 0.00000000000000007088 79.0
HFD2_k127_6804104_42 Belongs to the UPF0312 family - - - 0.000000003152 66.0
HFD2_k127_6804104_43 - - - - 0.00001617 50.0
HFD2_k127_6804104_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 598.0
HFD2_k127_6804104_6 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000088 587.0
HFD2_k127_6804104_7 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 531.0
HFD2_k127_6804104_8 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 532.0
HFD2_k127_6804104_9 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007523 521.0
HFD2_k127_6829162_0 UDP binding domain K00066 - 1.1.1.132 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 603.0
HFD2_k127_6829162_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 401.0
HFD2_k127_6829162_10 nuclease activity K18828 - - 0.000000000000000004985 88.0
HFD2_k127_6829162_12 amine dehydrogenase activity K14274 - - 0.0000005859 51.0
HFD2_k127_6829162_14 response to nickel cation - - - 0.0005921 45.0
HFD2_k127_6829162_15 response to nickel cation K07723 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0005938 46.0
HFD2_k127_6829162_16 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0009359 48.0
HFD2_k127_6829162_2 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 376.0
HFD2_k127_6829162_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 288.0
HFD2_k127_6829162_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008193 274.0
HFD2_k127_6829162_5 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001526 287.0
HFD2_k127_6829162_6 Histidine kinase K07683 - 2.7.13.3 0.000000000000000000000000000000000000000000000000001684 196.0
HFD2_k127_6829162_7 PIN domain - - - 0.0000000000000000000000000002931 119.0
HFD2_k127_6829162_8 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000002916 112.0
HFD2_k127_6843299_0 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000002674 265.0
HFD2_k127_6843299_1 deoxyhypusine monooxygenase activity K03301 - - 0.000000000000000000000000000000000000000000000000000000000006839 221.0
HFD2_k127_6843299_2 YtxH-like protein - - - 0.00000000000000000000001147 102.0
HFD2_k127_6850949_0 TonB-dependent receptor - - - 1.47e-259 840.0
HFD2_k127_6850949_1 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005791 491.0
HFD2_k127_6850949_10 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000371 154.0
HFD2_k127_6850949_11 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.000000000000000000000000000000000000001898 154.0
HFD2_k127_6850949_12 efflux transmembrane transporter activity - - - 0.0000000000000000000000000081 123.0
HFD2_k127_6850949_13 efflux transmembrane transporter activity - - - 0.000000000001874 74.0
HFD2_k127_6850949_14 Phage derived protein Gp49-like (DUF891) - - - 0.0000000003921 63.0
HFD2_k127_6850949_15 MacB-like periplasmic core domain - - - 0.00005876 49.0
HFD2_k127_6850949_2 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009878 445.0
HFD2_k127_6850949_3 Trehalose utilisation K09992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 424.0
HFD2_k127_6850949_4 Concanavalin A-like lectin/glucanases superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 309.0
HFD2_k127_6850949_5 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000002013 277.0
HFD2_k127_6850949_6 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000001508 259.0
HFD2_k127_6850949_7 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000006071 256.0
HFD2_k127_6850949_8 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000009705 232.0
HFD2_k127_6850949_9 lyase activity - - - 0.00000000000000000000000000000000000000000000000000005654 199.0
HFD2_k127_6855690_0 FAD linked oxidases, C-terminal domain - - - 3.453e-296 922.0
HFD2_k127_6855690_1 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 5.956e-235 755.0
HFD2_k127_6855690_10 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.0000000000000000000000000000000000000000000000000000000000107 208.0
HFD2_k127_6855690_11 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000000000000001134 168.0
HFD2_k127_6855690_13 - - - - 0.000001807 58.0
HFD2_k127_6855690_2 PFAM Glycosyl transferase, family K00756,K00758 - 2.4.2.2,2.4.2.4 1.033e-227 710.0
HFD2_k127_6855690_3 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 3.989e-217 688.0
HFD2_k127_6855690_4 PFAM Na dependent nucleoside transporter K03317 - - 7.794e-198 644.0
HFD2_k127_6855690_5 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 514.0
HFD2_k127_6855690_6 Aldose 1-epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 419.0
HFD2_k127_6855690_7 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 410.0
HFD2_k127_6855690_8 Pectic acid lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 374.0
HFD2_k127_6855690_9 PFAM Neutral alkaline nonlysosomal ceramidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002769 257.0
HFD2_k127_6864325_0 Sulfite reductase K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 5.878e-299 934.0
HFD2_k127_6864325_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 1.988e-270 849.0
HFD2_k127_6864325_10 PFAM molybdopterin dehydrogenase, FAD-binding K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 427.0
HFD2_k127_6864325_11 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 350.0
HFD2_k127_6864325_12 AIR synthase related protein, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001307 289.0
HFD2_k127_6864325_13 2Fe-2S -binding K13483 - - 0.00000000000000000000000000000000000000000000000000000000000000000007536 236.0
HFD2_k127_6864325_14 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000000101 208.0
HFD2_k127_6864325_15 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000002442 145.0
HFD2_k127_6864325_16 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000002828 154.0
HFD2_k127_6864325_17 domain, Protein - - - 0.0000000000000000000000000004406 118.0
HFD2_k127_6864325_18 - - - - 0.000000000000000000000000007373 118.0
HFD2_k127_6864325_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 4.628e-244 762.0
HFD2_k127_6864325_3 Anion-transporting ATPase K01551 - 3.6.3.16 4.321e-226 706.0
HFD2_k127_6864325_4 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 596.0
HFD2_k127_6864325_5 TonB-dependent Receptor Plug - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 578.0
HFD2_k127_6864325_6 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 552.0
HFD2_k127_6864325_7 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005646 519.0
HFD2_k127_6864325_8 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 452.0
HFD2_k127_6864325_9 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 462.0
HFD2_k127_6866199_0 homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 394.0
HFD2_k127_6866199_1 Belongs to the SUA5 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 321.0
HFD2_k127_6866199_2 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 316.0
HFD2_k127_6886098_0 allophanate hydrolase subunit 2 K01941,K06350 - 6.3.4.6 4.444e-298 951.0
HFD2_k127_6886098_1 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 340.0
HFD2_k127_6886098_10 Involved in the tonB-independent uptake of proteins K12132,K20276 - 2.7.11.1 0.000000000004606 79.0
HFD2_k127_6886098_11 Protein of unknown function (DUF3830) - - - 0.0000000008047 68.0
HFD2_k127_6886098_2 Peptidase S9 prolyl oligopeptidase active site domain protein K01303 - 3.4.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 334.0
HFD2_k127_6886098_3 cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 312.0
HFD2_k127_6886098_4 transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006761 278.0
HFD2_k127_6886098_5 creatininase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001096 274.0
HFD2_k127_6886098_6 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000002344 238.0
HFD2_k127_6886098_7 SMART Tetratricopeptide domain protein - - - 0.0000000000000000000000000000000000000000000001056 185.0
HFD2_k127_6886098_8 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000001655 157.0
HFD2_k127_6886098_9 - - - - 0.000000000000000000000000000000000002612 159.0
HFD2_k127_6888702_0 mandelate racemase muconate lactonizing K08323 - 4.2.1.8 1.217e-230 719.0
HFD2_k127_6888702_1 PFAM Cytochrome c assembly protein K02198 - - 1.001e-224 701.0
HFD2_k127_6888702_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 366.0
HFD2_k127_6888702_3 PFAM Cytochrome c assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 322.0
HFD2_k127_6888702_4 PFAM Cytochrome c-type biogenesis protein CcmB K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 322.0
HFD2_k127_6888702_5 Hydrolase of X-linked nucleoside diphosphate N terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004583 268.0
HFD2_k127_6888702_6 - - - - 0.00000000000000000000000000000000000000000000000008951 180.0
HFD2_k127_6888702_7 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000005943 139.0
HFD2_k127_6919265_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 2.181e-225 704.0
HFD2_k127_6919265_1 TonB-dependent Receptor Plug Domain K02014 - - 1.087e-196 635.0
HFD2_k127_6919265_2 PFAM oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 477.0
HFD2_k127_6919265_3 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 424.0
HFD2_k127_6919265_4 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 374.0
HFD2_k127_6919265_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 331.0
HFD2_k127_6919265_6 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000000000000000000000002397 183.0
HFD2_k127_6919265_7 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000000000007876 141.0
HFD2_k127_6919265_8 DinB family - - - 0.000000000000000000000000001175 119.0
HFD2_k127_6919265_9 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000007891 80.0
HFD2_k127_6939790_0 ABC transporter K06147 - - 9.723e-241 757.0
HFD2_k127_6939790_1 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688 - 2.4.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 606.0
HFD2_k127_6939790_2 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000137 248.0
HFD2_k127_6939790_3 - - - - 0.0000004932 51.0
HFD2_k127_6954209_0 Patatin-like phospholipase - - - 4.216e-234 755.0
HFD2_k127_6954209_1 alpha beta - - - 4.912e-222 702.0
HFD2_k127_6954209_2 phosphoglucosamine mutase activity K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 578.0
HFD2_k127_6954209_3 phosphoglucosamine mutase activity K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 525.0
HFD2_k127_6954209_4 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 400.0
HFD2_k127_6954209_5 BlaR1 peptidase M56 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 387.0
HFD2_k127_6954209_6 glycoside hydrolase family 2, TIM barrel K01192 - 3.2.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 324.0
HFD2_k127_6954209_7 Carbohydrate family 9 binding domain-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001044 251.0
HFD2_k127_6954209_8 Penicillinase repressor - - - 0.0000000000000000000000000000000000000000000002882 170.0
HFD2_k127_6954209_9 4-amino-4-deoxy-L-arabinose transferase activity K16928 - - 0.00000001742 66.0
HFD2_k127_6999081_0 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 5.341e-250 785.0
HFD2_k127_6999081_1 single-stranded-DNA-specific exonuclease RecJ K07462 - - 3.416e-247 775.0
HFD2_k127_6999081_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000003451 163.0
HFD2_k127_6999081_11 Belongs to the 'phage' integrase family K04763 - - 0.00000000000000000000000000173 126.0
HFD2_k127_6999081_12 DNA-templated transcription, initiation - - - 0.0000000007846 66.0
HFD2_k127_6999081_2 Aldehyde dehydrogenase family K04072,K15515 - 1.1.1.1,1.2.1.10,1.2.1.81 3.545e-230 728.0
HFD2_k127_6999081_3 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 346.0
HFD2_k127_6999081_4 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 295.0
HFD2_k127_6999081_5 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002391 291.0
HFD2_k127_6999081_6 PFAM Peptidase M22, glycoprotease K14742 - - 0.00000000000000000000000000000000000000000000000000000000000000000000707 244.0
HFD2_k127_6999081_8 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000006066 221.0
HFD2_k127_6999081_9 ethanolamine catabolic process - - - 0.00000000000000000000000000000000000003135 148.0
HFD2_k127_7002746_0 PFAM TonB-dependent Receptor Plug - - - 0.0 1328.0
HFD2_k127_7002746_1 Elongation factor G, domain IV K02355 - - 0.0 1152.0
HFD2_k127_7002746_10 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 314.0
HFD2_k127_7002746_11 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 312.0
HFD2_k127_7002746_12 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001495 292.0
HFD2_k127_7002746_13 HAD-hyrolase-like K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000000002666 237.0
HFD2_k127_7002746_14 MgtC family K07507 - - 0.00000000000000000000000000000000000000000007416 166.0
HFD2_k127_7002746_15 - - - - 0.00000000000000000000000000000000000002954 160.0
HFD2_k127_7002746_16 efflux transmembrane transporter activity - - - 0.0000000000000000000000007634 107.0
HFD2_k127_7002746_2 carboxylic acid catabolic process - - - 2.043e-218 683.0
HFD2_k127_7002746_3 Lysin motif K08307 - - 2.711e-197 630.0
HFD2_k127_7002746_4 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 546.0
HFD2_k127_7002746_5 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 518.0
HFD2_k127_7002746_6 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 528.0
HFD2_k127_7002746_7 thiamine diphosphate biosynthetic process K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 436.0
HFD2_k127_7002746_8 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000918 411.0
HFD2_k127_7002746_9 cellular response to dsDNA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 383.0
HFD2_k127_7019267_0 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 321.0
HFD2_k127_7019267_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 321.0
HFD2_k127_7019267_2 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000007404 218.0
HFD2_k127_7029446_0 ISXO2-like transposase domain - - - 0.0000000000000000000000000000000000000000007 161.0
HFD2_k127_7029446_1 ISXO2-like transposase domain - - - 0.0000000000000000000000000000000000002405 146.0
HFD2_k127_7029446_2 Bacterial membrane protein, YfhO - - - 0.000000000000000000000000000000000001235 145.0
HFD2_k127_7030509_0 Dehydrogenase E1 component K11381 - 1.2.4.4 0.0 1065.0
HFD2_k127_7030509_1 CHAT domain - - - 0.0 1059.0
HFD2_k127_7030509_10 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 604.0
HFD2_k127_7030509_11 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 473.0
HFD2_k127_7030509_12 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 381.0
HFD2_k127_7030509_13 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 360.0
HFD2_k127_7030509_14 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 323.0
HFD2_k127_7030509_16 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000007666 151.0
HFD2_k127_7030509_18 - - - - 0.000000000000000000000000000005433 123.0
HFD2_k127_7030509_19 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000003809 135.0
HFD2_k127_7030509_2 Thioredoxin-like K04084 - 1.8.1.8 6.881e-313 979.0
HFD2_k127_7030509_20 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000009891 98.0
HFD2_k127_7030509_21 - - - - 0.00000000005801 67.0
HFD2_k127_7030509_22 MacB-like periplasmic core domain - - - 0.00004851 54.0
HFD2_k127_7030509_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 5.217e-309 966.0
HFD2_k127_7030509_4 efflux transmembrane transporter activity - - - 5.89e-305 955.0
HFD2_k127_7030509_5 transport - - - 1.936e-292 932.0
HFD2_k127_7030509_6 MacB-like periplasmic core domain - - - 3.608e-269 852.0
HFD2_k127_7030509_7 GMC oxidoreductase - - - 1.385e-239 754.0
HFD2_k127_7030509_8 TonB-dependent receptor - - - 1.438e-237 771.0
HFD2_k127_7030509_9 inositol 2-dehydrogenase activity - - - 1.326e-218 689.0
HFD2_k127_7048221_0 protein kinase activity K13582,K13924 - 2.1.1.80,3.1.1.61 0.0 1065.0
HFD2_k127_7048221_1 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335 - 1.6.5.3 6.32e-216 686.0
HFD2_k127_7048221_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000003294 252.0
HFD2_k127_7048221_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000009664 236.0
HFD2_k127_7048221_4 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000009974 170.0
HFD2_k127_7059900_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 566.0
HFD2_k127_7059900_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.000000000000000000000000000000000000000000000009227 179.0
HFD2_k127_7060662_0 Belongs to the PstS family K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 477.0
HFD2_k127_7060662_1 Histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 466.0
HFD2_k127_7087188_0 Carboxypeptidase regulatory-like domain - - - 0.0 1047.0
HFD2_k127_7087188_1 Glycosyl transferase, family 2 - - - 3.094e-249 783.0
HFD2_k127_7087188_2 TIGRFAM glutamate formiminotransferase K00603,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 591.0
HFD2_k127_7087188_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 509.0
HFD2_k127_7087188_4 PFAM Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 323.0
HFD2_k127_7087188_5 PIN domain - - - 0.000000000000000000002371 99.0
HFD2_k127_7091707_0 Carboxypeptidase regulatory-like domain - - - 1.61e-321 1020.0
HFD2_k127_7091707_1 pyrroloquinoline quinone binding - - - 2.727e-232 728.0
HFD2_k127_7091707_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 589.0
HFD2_k127_7091707_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 439.0
HFD2_k127_7091707_4 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007315 320.0
HFD2_k127_7091707_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007494 271.0
HFD2_k127_7091707_6 - - - - 0.00000000000000000000000000000000000000000000001226 183.0
HFD2_k127_7091707_7 arylsulfatase activity - - - 0.000000000000004932 78.0
HFD2_k127_7092139_0 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 567.0
HFD2_k127_7092139_1 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 518.0
HFD2_k127_7092139_3 Ribosomal protein L11/L12 K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005276 256.0
HFD2_k127_7092139_4 - - - - 0.000000000000000000000000000000000000000000000001051 185.0
HFD2_k127_7092139_5 lipase activity - - - 0.00000000000000000000000000000000000000000000405 176.0
HFD2_k127_7092139_6 - - - - 0.00000000000000000000000000000000000000003009 160.0
HFD2_k127_709503_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 604.0
HFD2_k127_709503_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 592.0
HFD2_k127_709503_10 Cobalamin-independent synthase, Catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006922 364.0
HFD2_k127_709503_11 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 354.0
HFD2_k127_709503_12 Domain of unknown function (DUF5060) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 367.0
HFD2_k127_709503_13 Trehalose utilisation K09992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 346.0
HFD2_k127_709503_14 Trehalose utilisation K09992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 319.0
HFD2_k127_709503_15 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 284.0
HFD2_k127_709503_16 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000041 222.0
HFD2_k127_709503_17 pyrroloquinoline quinone binding K12349 - 3.5.1.23 0.0000000000000000000000000000000000000000000000000000004972 214.0
HFD2_k127_709503_18 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000000000000000000000000000000000000000007105 215.0
HFD2_k127_709503_19 - - - - 0.0000000000000000000000000000000000000000000000004774 178.0
HFD2_k127_709503_2 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 555.0
HFD2_k127_709503_20 - - - - 0.000000000000000000000000000002066 128.0
HFD2_k127_709503_21 PHP domain protein - - - 0.000000000000000000000000000002367 131.0
HFD2_k127_709503_22 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000003874 123.0
HFD2_k127_709503_23 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000004064 122.0
HFD2_k127_709503_24 gamma-carboxymuconolactone decarboxylase subunit - - - 0.000000000000000000000000007609 113.0
HFD2_k127_709503_25 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000001899 102.0
HFD2_k127_709503_27 PIN domain - - - 0.00000001071 60.0
HFD2_k127_709503_28 Plasmid stability protein K21495 - - 0.0001283 47.0
HFD2_k127_709503_3 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005573 544.0
HFD2_k127_709503_4 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 514.0
HFD2_k127_709503_5 PLD-like domain K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 464.0
HFD2_k127_709503_6 D-mannonate dehydratase (UxuA) K01686 - 4.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 445.0
HFD2_k127_709503_7 aminopeptidase activity K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007352 450.0
HFD2_k127_709503_8 Sh3 type 3 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 404.0
HFD2_k127_709503_9 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 379.0
HFD2_k127_7126542_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009368 533.0
HFD2_k127_7126542_1 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000856 354.0
HFD2_k127_7126542_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005435 269.0
HFD2_k127_7126542_3 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001614 250.0
HFD2_k127_7126542_4 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000475 185.0
HFD2_k127_7126542_5 ECF sigma factor - - - 0.0000000000000000000000003166 109.0
HFD2_k127_7126542_6 DNA-templated transcription, initiation K02405 - - 0.00000009682 56.0
HFD2_k127_7137426_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1192.0
HFD2_k127_7137426_1 PFAM Uncharacterised BCR, COG1649 - - - 0.0 1187.0
HFD2_k127_7137426_10 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 414.0
HFD2_k127_7137426_11 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 397.0
HFD2_k127_7137426_12 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 388.0
HFD2_k127_7137426_13 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 341.0
HFD2_k127_7137426_14 bacterial (prokaryotic) histone like domain K03530 - - 0.00000000000000000000000000000000000000000000000002521 179.0
HFD2_k127_7137426_15 TIGRFAM phosphoesterase, MJ0936 family K07095 - - 0.000000000000000000000000000000000000000000000106 172.0
HFD2_k127_7137426_16 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000007287 178.0
HFD2_k127_7137426_17 FMN binding - - - 0.000000000000000000000000000000000000000000003464 176.0
HFD2_k127_7137426_19 Protein of unknown function (DUF433) - - - 0.000000000000000000000005787 106.0
HFD2_k127_7137426_2 siderophore transport K02014 - - 6.986e-310 993.0
HFD2_k127_7137426_20 - - - - 0.00000000000000000001472 96.0
HFD2_k127_7137426_21 - - - - 0.000000000001283 73.0
HFD2_k127_7137426_22 Glycosyl transferases group 1 - - - 0.00000003119 61.0
HFD2_k127_7137426_3 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.529e-252 793.0
HFD2_k127_7137426_4 PFAM oxidoreductase domain protein - - - 5.568e-244 761.0
HFD2_k127_7137426_5 PFAM oxidoreductase domain protein - - - 5.947e-212 664.0
HFD2_k127_7137426_6 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 610.0
HFD2_k127_7137426_7 MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007878 546.0
HFD2_k127_7137426_8 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 482.0
HFD2_k127_7137426_9 Glycosyl transferase, family 2 K12984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 419.0
HFD2_k127_7153592_0 siderophore transport K02014 - - 0.0 1377.0
HFD2_k127_7153592_1 - - - - 5.393e-215 702.0
HFD2_k127_7153592_2 PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008314 499.0
HFD2_k127_7164497_0 FMN binding - - - 4.344e-235 737.0
HFD2_k127_7164497_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 2.406e-198 628.0
HFD2_k127_7164497_2 Phosphoribosyl transferase domain K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 288.0
HFD2_k127_7164497_3 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000003794 218.0
HFD2_k127_718445_0 4Fe-4S dicluster domain K00184 - - 0.0 1444.0
HFD2_k127_718445_1 transport - - - 1.908e-320 1023.0
HFD2_k127_718445_10 PFAM peptidase T2 asparaginase 2 K01444 - 3.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 473.0
HFD2_k127_718445_11 PFAM ATP-binding region, ATPase domain protein domain protein K07683 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 453.0
HFD2_k127_718445_12 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 401.0
HFD2_k127_718445_13 signal sequence binding K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 398.0
HFD2_k127_718445_14 Gamma-glutamyltranspeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 417.0
HFD2_k127_718445_15 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 331.0
HFD2_k127_718445_16 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 297.0
HFD2_k127_718445_17 COGs COG4299 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009294 292.0
HFD2_k127_718445_18 Pfam Sulfatase K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001859 286.0
HFD2_k127_718445_19 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000009151 262.0
HFD2_k127_718445_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 5.575e-313 965.0
HFD2_k127_718445_20 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001246 267.0
HFD2_k127_718445_21 polysaccharide export K01991,K16552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003248 276.0
HFD2_k127_718445_22 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001812 246.0
HFD2_k127_718445_23 proline dipeptidase activity K08688 - 3.5.3.3 0.0000000000000000000000000000000000000000000000000000000000002267 227.0
HFD2_k127_718445_24 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000002496 217.0
HFD2_k127_718445_25 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000000000000000000000000000000000000000000000000000000004971 210.0
HFD2_k127_718445_26 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000129 203.0
HFD2_k127_718445_27 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000004296 163.0
HFD2_k127_718445_28 - - - - 0.000000000000000000000000000000001439 136.0
HFD2_k127_718445_29 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.00000000000000000000000001527 116.0
HFD2_k127_718445_3 PFAM Polysulphide reductase, NrfD K00185 - - 7.527e-242 754.0
HFD2_k127_718445_31 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000004214 79.0
HFD2_k127_718445_32 - - - - 0.0001568 53.0
HFD2_k127_718445_4 Carboxypeptidase regulatory-like domain - - - 1.182e-197 654.0
HFD2_k127_718445_5 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 639.0
HFD2_k127_718445_6 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 541.0
HFD2_k127_718445_7 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 533.0
HFD2_k127_718445_8 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006099 531.0
HFD2_k127_718445_9 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008026 480.0
HFD2_k127_7214783_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.471e-235 738.0
HFD2_k127_7214783_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 583.0
HFD2_k127_7214783_10 BNR repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 300.0
HFD2_k127_7214783_11 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000006264 192.0
HFD2_k127_7214783_12 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000000002092 181.0
HFD2_k127_7214783_13 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000007033 72.0
HFD2_k127_7214783_14 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0007766 51.0
HFD2_k127_7214783_2 He_PIG associated, NEW1 domain of bacterial glycohydrolase K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 572.0
HFD2_k127_7214783_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 528.0
HFD2_k127_7214783_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 520.0
HFD2_k127_7214783_5 PFAM Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 435.0
HFD2_k127_7214783_6 nucleotide metabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009192 378.0
HFD2_k127_7214783_7 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008062 377.0
HFD2_k127_7214783_8 Pectate lyase superfamily protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 377.0
HFD2_k127_7214783_9 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009693 327.0
HFD2_k127_7246645_0 Conserved carboxylase domain K01958 - 6.4.1.1 0.0 1896.0
HFD2_k127_7246645_1 Aminotransferase - - - 1.387e-211 661.0
HFD2_k127_7246645_2 PFAM SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 441.0
HFD2_k127_7246645_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000608 162.0
HFD2_k127_7269989_0 FtsX-like permease family - - - 0.0 1501.0
HFD2_k127_7269989_1 MacB-like periplasmic core domain - - - 0.0 1089.0
HFD2_k127_7269989_10 Alginate export - - - 0.0000000000000000000000000000000000000000000000000000000000000007054 237.0
HFD2_k127_7269989_11 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000002263 239.0
HFD2_k127_7269989_12 Trehalose utilisation K09992 - - 0.0000000000000000000000000000000000000000000000000000000000000109 232.0
HFD2_k127_7269989_13 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000000000000000000002094 213.0
HFD2_k127_7269989_14 PIN domain - - - 0.0000000000000000000000000000000000005436 144.0
HFD2_k127_7269989_15 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.0000000000000000000000000000102 125.0
HFD2_k127_7269989_16 membrane protein (DUF2306) - - - 0.0000000000000000000000000001423 134.0
HFD2_k127_7269989_17 Transcriptional regulator PadR-like family - - - 0.0000000000000000004866 91.0
HFD2_k127_7269989_18 - - - - 0.000000000000000002865 89.0
HFD2_k127_7269989_19 PFAM alpha beta hydrolase fold - - - 0.00000000000000891 84.0
HFD2_k127_7269989_2 His Kinase A (phosphoacceptor) domain - - - 2.932e-219 698.0
HFD2_k127_7269989_20 Peptidase family S58 - - - 0.000000002355 67.0
HFD2_k127_7269989_21 - - - - 0.000000003145 63.0
HFD2_k127_7269989_22 AAA ATPase domain - - - 0.0000001239 57.0
HFD2_k127_7269989_23 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.00000468 54.0
HFD2_k127_7269989_24 membrane protein (DUF2306) - - - 0.0001242 52.0
HFD2_k127_7269989_3 MacB-like periplasmic core domain - - - 1.803e-209 678.0
HFD2_k127_7269989_4 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 578.0
HFD2_k127_7269989_5 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 494.0
HFD2_k127_7269989_6 peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 458.0
HFD2_k127_7269989_7 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 350.0
HFD2_k127_7269989_8 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008233 335.0
HFD2_k127_7269989_9 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 312.0
HFD2_k127_7271701_0 Zinc carboxypeptidase K14054 - - 4.217e-215 676.0
HFD2_k127_7271701_1 Zinc carboxypeptidase K14054 - - 0.00000000000000000000000000000000006184 134.0
HFD2_k127_7273421_0 phospholipase C - - - 0.0 1102.0
HFD2_k127_7273421_1 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 9.24e-322 996.0
HFD2_k127_7273421_10 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 597.0
HFD2_k127_7273421_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 546.0
HFD2_k127_7273421_12 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 514.0
HFD2_k127_7273421_13 transmembrane transporter activity K03535,K08194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 534.0
HFD2_k127_7273421_14 Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 479.0
HFD2_k127_7273421_15 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 471.0
HFD2_k127_7273421_16 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 470.0
HFD2_k127_7273421_17 histidine ammonia-lyase K10775 - 4.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007338 450.0
HFD2_k127_7273421_18 homoserine dehydrogenase activity K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005783 424.0
HFD2_k127_7273421_19 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 407.0
HFD2_k127_7273421_2 4-alpha-glucanotransferase K00705 - 2.4.1.25 1.826e-316 987.0
HFD2_k127_7273421_20 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 412.0
HFD2_k127_7273421_21 cyclic nucleotide binding K00384,K10914 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 391.0
HFD2_k127_7273421_22 Protein phosphatase 2C K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 347.0
HFD2_k127_7273421_23 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 340.0
HFD2_k127_7273421_24 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 340.0
HFD2_k127_7273421_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 324.0
HFD2_k127_7273421_26 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 334.0
HFD2_k127_7273421_27 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 327.0
HFD2_k127_7273421_28 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 286.0
HFD2_k127_7273421_29 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000944 269.0
HFD2_k127_7273421_3 PFAM LmbE family protein - - - 9.469e-277 875.0
HFD2_k127_7273421_30 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005612 271.0
HFD2_k127_7273421_31 NIPSNAP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008406 268.0
HFD2_k127_7273421_32 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000003803 242.0
HFD2_k127_7273421_33 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002936 241.0
HFD2_k127_7273421_34 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000003777 235.0
HFD2_k127_7273421_35 Conserved repeat domain - - - 0.0000000000000000000000000000000000000000000000000000000000000007701 237.0
HFD2_k127_7273421_36 - - - - 0.00000000000000000000000000000000000000000000000000000000000001501 240.0
HFD2_k127_7273421_37 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000000000000000000000000000000000000000000003729 199.0
HFD2_k127_7273421_38 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000009427 191.0
HFD2_k127_7273421_39 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000000000000000000000000000000000000003616 190.0
HFD2_k127_7273421_4 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 3.852e-247 777.0
HFD2_k127_7273421_40 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000001147 196.0
HFD2_k127_7273421_41 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000000000000000000000000002109 183.0
HFD2_k127_7273421_42 - - - - 0.0000000000000000000000000000000000000000000005221 173.0
HFD2_k127_7273421_43 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000000001307 167.0
HFD2_k127_7273421_44 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000000102 149.0
HFD2_k127_7273421_46 Domain of unknown function (DUF4115) - - - 0.0000000000000000004654 100.0
HFD2_k127_7273421_47 ThiS family K03154 - - 0.0000000000000000004776 89.0
HFD2_k127_7273421_5 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 8.822e-233 733.0
HFD2_k127_7273421_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 5.489e-223 704.0
HFD2_k127_7273421_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.193e-219 685.0
HFD2_k127_7273421_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 5.852e-203 642.0
HFD2_k127_7273421_9 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 624.0
HFD2_k127_7281520_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000001355 253.0
HFD2_k127_7281520_1 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000000002109 183.0
HFD2_k127_7281520_2 - - - - 0.000000000000000007949 98.0
HFD2_k127_7281520_3 metallopeptidase activity - - - 0.000000003809 62.0
HFD2_k127_7295334_0 domain, Protein - - - 0.0 1076.0
HFD2_k127_7295334_1 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005915 522.0
HFD2_k127_7323056_0 TonB-dependent receptor - - - 2.726e-261 837.0
HFD2_k127_7323056_1 L-seryl-tRNASec selenium transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 542.0
HFD2_k127_7323056_2 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 340.0
HFD2_k127_7323056_3 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 299.0
HFD2_k127_7323056_4 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000000000000000000000000000002433 179.0
HFD2_k127_7323056_5 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000006462 148.0
HFD2_k127_7323056_6 Aminoglycoside phosphotransferase - - - 0.000000000000000004198 96.0
HFD2_k127_7331078_0 Ferric reductase like transmembrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 428.0
HFD2_k127_7331078_1 lipopolysaccharide transport K22110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 418.0
HFD2_k127_7331078_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009823 400.0
HFD2_k127_7331078_3 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000004421 241.0
HFD2_k127_7331078_4 Yhs domain-containing protein - - - 0.000000000000000000000000000000000000000000001335 168.0
HFD2_k127_7331078_5 - - - - 0.00000000000000000000000000000000000002109 156.0
HFD2_k127_7331078_6 SMART Phospholipid glycerol acyltransferase - - - 0.000000000000000000000000000000005923 138.0
HFD2_k127_7331078_7 - - - - 0.000000000000003879 78.0
HFD2_k127_7339729_0 3-demethylubiquinone-9 3-O-methyltransferase activity K18827 - 2.1.1.294,2.7.1.181 3.911e-311 963.0
HFD2_k127_7339729_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008104 512.0
HFD2_k127_7339729_2 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 514.0
HFD2_k127_7339729_3 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 508.0
HFD2_k127_7339729_4 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 454.0
HFD2_k127_7339729_5 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 419.0
HFD2_k127_7339729_6 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 407.0
HFD2_k127_7339729_7 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001178 285.0
HFD2_k127_7339729_9 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000002829 135.0
HFD2_k127_735054_0 Belongs to the UbiD family K03182 - 4.1.1.98 2.682e-275 853.0
HFD2_k127_735054_1 choline dehydrogenase activity K03333 - 1.1.3.6 5.64e-210 666.0
HFD2_k127_735054_10 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001319 263.0
HFD2_k127_735054_11 PFAM NHL repeat containing protein K13735 - - 0.0000000000000000000000000000000008421 148.0
HFD2_k127_735054_12 Beta-propeller repeat - - - 0.000000000000000003616 97.0
HFD2_k127_735054_13 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000667 66.0
HFD2_k127_735054_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 576.0
HFD2_k127_735054_3 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 425.0
HFD2_k127_735054_4 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 411.0
HFD2_k127_735054_5 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 389.0
HFD2_k127_735054_6 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 388.0
HFD2_k127_735054_7 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006298 368.0
HFD2_k127_735054_8 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 383.0
HFD2_k127_735054_9 Tfp pilus assembly protein tip-associated adhesin K02674,K14379 - 3.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 337.0
HFD2_k127_7361790_0 transport - - - 0.0 1047.0
HFD2_k127_7361790_1 Glucose / Sorbosone dehydrogenase - - - 5.16e-261 816.0
HFD2_k127_7361790_10 Cytochrome P460 - - - 0.00000000000000000000000000000002284 134.0
HFD2_k127_7361790_11 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.0000000000000000000000004221 122.0
HFD2_k127_7361790_12 efflux transmembrane transporter activity - - - 0.0000000000000000000006637 104.0
HFD2_k127_7361790_13 Alternative locus ID K11206 - - 0.0000000000000000003185 100.0
HFD2_k127_7361790_14 efflux transmembrane transporter activity - - - 0.00000002305 66.0
HFD2_k127_7361790_15 Erythromycin esterase K06880 - - 0.0006171 45.0
HFD2_k127_7361790_16 efflux transmembrane transporter activity - - - 0.0007031 52.0
HFD2_k127_7361790_2 - - - - 9.405e-214 682.0
HFD2_k127_7361790_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 2.211e-205 653.0
HFD2_k127_7361790_4 PFAM glycosyl transferase, family 28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 514.0
HFD2_k127_7361790_5 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 473.0
HFD2_k127_7361790_6 inositol 2-dehydrogenase activity K18106 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 446.0
HFD2_k127_7361790_7 BNR repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 359.0
HFD2_k127_7361790_8 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 283.0
HFD2_k127_7361790_9 Glutamine cyclotransferase - - - 0.000000000000000000000000000000000000000000000000001068 192.0
HFD2_k127_736689_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1463.0
HFD2_k127_736689_1 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 1.596e-218 703.0
HFD2_k127_736689_2 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 557.0
HFD2_k127_736689_3 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009584 540.0
HFD2_k127_736689_4 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 539.0
HFD2_k127_736689_5 Domain of Unknown Function (DUF1259) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 375.0
HFD2_k127_736689_6 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004702 376.0
HFD2_k127_736689_7 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000002667 157.0
HFD2_k127_736689_8 CoA binding domain K06929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000004407 94.0
HFD2_k127_7376377_0 AAA domain K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 362.0
HFD2_k127_7376377_1 Belongs to the GSP D family K02280 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 338.0
HFD2_k127_7376377_2 PFAM SAF domain K02279 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 290.0
HFD2_k127_7376377_4 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000005427 172.0
HFD2_k127_7376377_5 Belongs to the GSP D family K02280 - - 0.00000000000000000000000000000001758 142.0
HFD2_k127_7379255_0 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 3.089e-223 721.0
HFD2_k127_7379255_1 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 545.0
HFD2_k127_7379255_2 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 409.0
HFD2_k127_7379255_3 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 347.0
HFD2_k127_7379255_4 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001084 253.0
HFD2_k127_7379255_5 DinB superfamily - - - 0.00000000000000000000000000000000000000000000001173 177.0
HFD2_k127_7379255_6 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000003228 116.0
HFD2_k127_7379255_7 Phage integrase family - - - 0.0000000000000000000008577 100.0
HFD2_k127_7379255_8 Outer membrane efflux protein K18308 - - 0.00000000000000001884 91.0
HFD2_k127_7407396_0 Carboxypeptidase regulatory-like domain - - - 0.0 1306.0
HFD2_k127_7407396_1 4Fe-4S dicluster domain K00184 - - 2.06e-287 912.0
HFD2_k127_7407396_10 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 379.0
HFD2_k127_7407396_11 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 347.0
HFD2_k127_7407396_12 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 294.0
HFD2_k127_7407396_13 nitrate reductase activity K00370,K00374,K02575 GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000001993 225.0
HFD2_k127_7407396_14 Belongs to the P(II) protein family K04751,K04752 - - 0.000000000000000000000000000000000000000000000000000001566 194.0
HFD2_k127_7407396_15 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000001731 178.0
HFD2_k127_7407396_16 PFAM Cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000004475 183.0
HFD2_k127_7407396_17 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000009196 184.0
HFD2_k127_7407396_18 Predicted metal-binding protein (DUF2103) - - - 0.0000000000000000000000000000000000000008838 149.0
HFD2_k127_7407396_19 cytochrome c - - - 0.000000000000000000000000000000000000009922 159.0
HFD2_k127_7407396_2 TIGRFAM Ammonium transporter K03320 - - 5.034e-228 713.0
HFD2_k127_7407396_20 RNA recognition motif - - - 0.0000000000000000000000000000000000002072 150.0
HFD2_k127_7407396_21 PFAM Nitrate reductase delta subunit K00373 - - 0.00000000000002278 82.0
HFD2_k127_7407396_22 - - - - 0.0000000003805 67.0
HFD2_k127_7407396_23 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000006312 57.0
HFD2_k127_7407396_24 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.0001577 49.0
HFD2_k127_7407396_3 nitrate reductase beta subunit K00371 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 4.392e-226 709.0
HFD2_k127_7407396_4 Polysulphide reductase, NrfD K00185 - - 1.595e-221 694.0
HFD2_k127_7407396_5 Phospholipase B - - - 2.078e-207 672.0
HFD2_k127_7407396_6 Major Facilitator Superfamily K02575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 527.0
HFD2_k127_7407396_7 AIR synthase related protein, C-terminal domain K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 480.0
HFD2_k127_7407396_8 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000951 469.0
HFD2_k127_7407396_9 C4-dicarboxylate transporter malic acid transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 384.0
HFD2_k127_7452050_0 heavy metal translocating P-type ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 2.111e-253 803.0
HFD2_k127_7452050_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 3.126e-216 678.0
HFD2_k127_7452050_10 von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007282 451.0
HFD2_k127_7452050_11 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 404.0
HFD2_k127_7452050_12 FES K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007663 421.0
HFD2_k127_7452050_13 oxidation-reduction process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008405 385.0
HFD2_k127_7452050_14 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 375.0
HFD2_k127_7452050_15 PFAM Alcohol dehydrogenase GroES-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 299.0
HFD2_k127_7452050_16 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001229 285.0
HFD2_k127_7452050_17 PFAM Ribonuclease BN-like family K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005662 297.0
HFD2_k127_7452050_18 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000009589 252.0
HFD2_k127_7452050_19 Cyclase dehydrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000395 252.0
HFD2_k127_7452050_2 radical SAM domain protein - - - 2.115e-205 651.0
HFD2_k127_7452050_20 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000006092 245.0
HFD2_k127_7452050_21 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.000000000000000000000000000000000000000000000000000000000000002046 226.0
HFD2_k127_7452050_22 PRC-barrel domain - - - 0.00000000000000000000000000000000000000000001741 168.0
HFD2_k127_7452050_23 Low molecular weight phosphatase family - - - 0.00000000000000000000000000000000000001622 154.0
HFD2_k127_7452050_24 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000002776 141.0
HFD2_k127_7452050_26 Transglycosylase associated protein - - - 0.0000000000000000000000002332 110.0
HFD2_k127_7452050_27 Protein of unknown function (DUF1003) - - - 0.0000000000000000005704 96.0
HFD2_k127_7452050_28 Protein of unknown function (DUF1003) - - - 0.0000000000000000142 85.0
HFD2_k127_7452050_29 mercury ion transmembrane transporter activity K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000001446 78.0
HFD2_k127_7452050_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 3.477e-194 617.0
HFD2_k127_7452050_30 Short-chain dehydrogenase reductase (SDR) - - - 0.000000000000001517 79.0
HFD2_k127_7452050_4 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008745 524.0
HFD2_k127_7452050_5 helix_turn_helix gluconate operon transcriptional repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006833 497.0
HFD2_k127_7452050_6 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007767 490.0
HFD2_k127_7452050_7 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 492.0
HFD2_k127_7452050_8 Oxidoreductase family, C-terminal alpha beta domain K00118,K13020 - 1.1.1.335,1.1.99.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 471.0
HFD2_k127_7452050_9 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 458.0
HFD2_k127_7464801_0 Carboxypeptidase regulatory-like domain - - - 2.158e-303 967.0
HFD2_k127_7464801_1 Carboxypeptidase regulatory-like domain - - - 3.15e-255 835.0
HFD2_k127_7464801_10 Planctomycete cytochrome C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 564.0
HFD2_k127_7464801_11 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000717 511.0
HFD2_k127_7464801_12 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 506.0
HFD2_k127_7464801_13 transferase activity, transferring glycosyl groups K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 484.0
HFD2_k127_7464801_14 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 470.0
HFD2_k127_7464801_15 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 442.0
HFD2_k127_7464801_16 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 413.0
HFD2_k127_7464801_17 domain, Protein K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 353.0
HFD2_k127_7464801_18 N-acetylglucosaminylinositol deacetylase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 295.0
HFD2_k127_7464801_19 N-acetylglucosaminylinositol deacetylase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 297.0
HFD2_k127_7464801_2 transport - - - 1.141e-241 782.0
HFD2_k127_7464801_20 Cell division protein FtsQ K03589 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 295.0
HFD2_k127_7464801_21 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001838 280.0
HFD2_k127_7464801_22 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003704 287.0
HFD2_k127_7464801_23 carboxylic acid catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001233 287.0
HFD2_k127_7464801_24 Glycosyl hydrolase family 20, catalytic domain K12373 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000001971 239.0
HFD2_k127_7464801_25 Cytochrome c K02720 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.00000000000000000000000000000000000000000002354 168.0
HFD2_k127_7464801_26 transmembrane transport - - - 0.00000000000000000000000000000000000000000462 172.0
HFD2_k127_7464801_27 Protein of unknown function (DUF3303) - - - 0.000000000000000000000000002585 114.0
HFD2_k127_7464801_28 SnoaL-like domain - - - 0.00000000000000007525 85.0
HFD2_k127_7464801_29 Hypothetical glycosyl hydrolase 6 - - - 0.00000000000006637 85.0
HFD2_k127_7464801_3 Carboxypeptidase regulatory-like domain - - - 1.974e-226 731.0
HFD2_k127_7464801_30 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.000000000008377 75.0
HFD2_k127_7464801_31 Catalyzes the NAD-dependent oxidation of glucose 6- phosphate to 6-phosphogluconolactone K19243 - 1.1.1.388 0.0000000002791 71.0
HFD2_k127_7464801_4 unsaturated chondroitin disaccharide hydrolase activity - - - 2.097e-200 656.0
HFD2_k127_7464801_5 Amidohydrolase family K06015 - 3.5.1.81 4.767e-200 642.0
HFD2_k127_7464801_6 Carboxypeptidase regulatory-like domain - - - 1.074e-199 644.0
HFD2_k127_7464801_7 Dehydrogenase K00117 - 1.1.5.2 1.109e-194 625.0
HFD2_k127_7464801_8 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006899 596.0
HFD2_k127_7464801_9 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 552.0
HFD2_k127_7570396_0 domain protein - - - 0.0 1900.0
HFD2_k127_7570396_1 Flavin containing amine oxidoreductase - - - 7.491e-279 863.0
HFD2_k127_7570396_2 ABC-2 type transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 305.0
HFD2_k127_7570396_3 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000007991 237.0
HFD2_k127_7570396_4 TIGRFAM malto-oligosyltrehalose trehalohydrolase K00700 - 2.4.1.18 0.00000000000000000000000000000000000000005022 152.0
HFD2_k127_7687409_0 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 413.0
HFD2_k127_7687409_1 TfuA-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 321.0
HFD2_k127_7687409_2 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006764 272.0
HFD2_k127_7693622_0 transport - - - 4.503e-315 1000.0
HFD2_k127_7693622_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 362.0
HFD2_k127_7693622_2 Belongs to the glycosyl hydrolase 43 family - - - 0.000000000000000000000000000000000000000000000000000000000004299 214.0
HFD2_k127_7693622_3 Sigma-70 region 2 - - - 0.000000000000000000000000000000000000000000000000000003899 207.0
HFD2_k127_7693622_4 - - - - 0.000000000000000000000000000003446 125.0
HFD2_k127_7749987_0 Carboxypeptidase regulatory-like domain - - - 1.202e-285 906.0
HFD2_k127_7749987_1 Aromatic amino acid lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 488.0
HFD2_k127_7787587_0 AcrB/AcrD/AcrF family - - - 0.0 1283.0
HFD2_k127_7787587_1 Protein of unknown function (DUF1553) - - - 0.0 1208.0
HFD2_k127_7787587_10 Carboxypeptidase regulatory-like domain - - - 1.651e-211 700.0
HFD2_k127_7787587_11 Erythromycin esterase - - - 2.788e-200 632.0
HFD2_k127_7787587_12 Chase2 domain - - - 1.006e-194 626.0
HFD2_k127_7787587_13 Bacterial regulatory protein, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007828 611.0
HFD2_k127_7787587_14 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 517.0
HFD2_k127_7787587_15 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007636 449.0
HFD2_k127_7787587_16 Myo-inositol oxygenase K00469 - 1.13.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 432.0
HFD2_k127_7787587_17 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 441.0
HFD2_k127_7787587_18 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008556 430.0
HFD2_k127_7787587_19 von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 414.0
HFD2_k127_7787587_2 TonB-dependent Receptor Plug Domain - - - 0.0 1169.0
HFD2_k127_7787587_20 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 413.0
HFD2_k127_7787587_21 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 377.0
HFD2_k127_7787587_22 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 357.0
HFD2_k127_7787587_23 COG3119 Arylsulfatase A K01132 - 3.1.6.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009066 373.0
HFD2_k127_7787587_24 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 299.0
HFD2_k127_7787587_25 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001455 295.0
HFD2_k127_7787587_26 Beta-galactosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002154 291.0
HFD2_k127_7787587_27 epimerase K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000025 266.0
HFD2_k127_7787587_28 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000005812 243.0
HFD2_k127_7787587_29 TIGRFAM molybdenum cofactor synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000002872 246.0
HFD2_k127_7787587_3 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1082.0
HFD2_k127_7787587_30 ornithine cyclodeaminase activity K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000003219 246.0
HFD2_k127_7787587_31 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002201 230.0
HFD2_k127_7787587_32 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000001247 235.0
HFD2_k127_7787587_33 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.000000000000000000000000000000000000000000000000000000003766 205.0
HFD2_k127_7787587_34 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000004117 195.0
HFD2_k127_7787587_36 AAA domain - - - 0.00000000000000000000000000000000000000000000001788 176.0
HFD2_k127_7787587_37 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000006103 172.0
HFD2_k127_7787587_38 - - - - 0.0000000000000000000000000000000000000000001621 169.0
HFD2_k127_7787587_39 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000000000000000001367 162.0
HFD2_k127_7787587_4 Protein of unknown function (DUF1501) - - - 9.297e-250 785.0
HFD2_k127_7787587_40 Protein of unknown function (DUF3467) K06603 - - 0.000000000000000000000000000000000000003095 150.0
HFD2_k127_7787587_41 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000001069 151.0
HFD2_k127_7787587_42 Intracellular proteinase inhibitor - - - 0.00000000000000000000000000000000000001317 162.0
HFD2_k127_7787587_43 Ribosomal_S15 K02956 - - 0.00000000000000000000000000000000000007858 155.0
HFD2_k127_7787587_44 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000007761 142.0
HFD2_k127_7787587_45 CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000000001632 132.0
HFD2_k127_7787587_46 HD domain - - - 0.0000000000000000000000000001889 123.0
HFD2_k127_7787587_47 PKD domain containing protein K01337,K20276,K21449 - 3.4.21.50 0.0000000000000000000000000002546 133.0
HFD2_k127_7787587_48 MacB-like periplasmic core domain - - - 0.000000000000000000000000001651 117.0
HFD2_k127_7787587_49 MacB-like periplasmic core domain - - - 0.00000000000000000000000001879 112.0
HFD2_k127_7787587_5 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 4.7e-246 775.0
HFD2_k127_7787587_50 - - - - 0.00000000000000000000000008536 115.0
HFD2_k127_7787587_54 4-Hydroxyphenylpyruvate dioxygenase K05606,K17315 - 5.1.99.1 0.000000008733 66.0
HFD2_k127_7787587_6 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 4.563e-233 748.0
HFD2_k127_7787587_7 Response regulator receiver - - - 3.332e-232 725.0
HFD2_k127_7787587_8 Aminotransferase class I and II K14261 - - 1.417e-224 699.0
HFD2_k127_7787587_9 Histidine kinase K21025 - - 2.134e-224 720.0
HFD2_k127_7821305_0 PFAM transposase IS66 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 557.0
HFD2_k127_7821305_1 Domain of unknown function (DUF4338) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008539 435.0
HFD2_k127_7821305_2 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006453 250.0
HFD2_k127_7821305_3 IS66 Orf2 like protein K07484 - - 0.0000000000000000000000000000000000000000000000000003471 189.0
HFD2_k127_7821305_4 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000001016 68.0
HFD2_k127_7830133_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 6.751e-240 748.0
HFD2_k127_7830133_1 O-methyltransferase activity - - - 7.668e-234 744.0
HFD2_k127_7830133_10 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 389.0
HFD2_k127_7830133_11 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 410.0
HFD2_k127_7830133_12 PFAM Major Facilitator Superfamily K08191 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 372.0
HFD2_k127_7830133_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007419 357.0
HFD2_k127_7830133_14 SpoU rRNA Methylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001014 258.0
HFD2_k127_7830133_15 - - - - 0.0000000000000000000000000000000000000001014 159.0
HFD2_k127_7830133_16 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000386 126.0
HFD2_k127_7830133_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 588.0
HFD2_k127_7830133_3 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 582.0
HFD2_k127_7830133_4 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 564.0
HFD2_k127_7830133_5 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 472.0
HFD2_k127_7830133_7 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 460.0
HFD2_k127_7830133_8 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009661 432.0
HFD2_k127_7830133_9 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 426.0
HFD2_k127_7836620_0 PFAM type II secretion system protein E K02283 - - 4.372e-229 725.0
HFD2_k127_7836620_1 Belongs to the GSP D family K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 545.0
HFD2_k127_7836620_2 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 503.0
HFD2_k127_7836620_3 AAA domain K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000762 455.0
HFD2_k127_7836620_4 type II secretion system K12510 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 309.0
HFD2_k127_7836620_5 PFAM SAF domain K02279 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000141 287.0
HFD2_k127_7836620_6 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000003714 115.0
HFD2_k127_784707_0 transport - - - 1.512e-306 979.0
HFD2_k127_784707_1 Rhs Family - - - 4.344e-297 974.0
HFD2_k127_784707_10 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000003726 113.0
HFD2_k127_784707_12 SCO1/SenC - - - 0.000000000000000002116 98.0
HFD2_k127_784707_13 PFAM Tetratricopeptide repeat - - - 0.000000000000000005427 98.0
HFD2_k127_784707_2 Carboxypeptidase regulatory-like domain - - - 6.725e-206 680.0
HFD2_k127_784707_3 Sugar (and other) transporter K08178 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 502.0
HFD2_k127_784707_4 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006319 461.0
HFD2_k127_784707_5 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 402.0
HFD2_k127_784707_6 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001146 283.0
HFD2_k127_784707_7 Aminotransferase, class V - - - 0.000000000000000000000000000000000000000000000000000000000000001718 233.0
HFD2_k127_784707_9 TonB dependent receptor K16087 - - 0.0000000000000000000000000000000000000000002592 183.0
HFD2_k127_7850819_0 ATPase domain of DNA mismatch repair MUTS family - - - 6.593e-207 661.0
HFD2_k127_7850819_1 peptidyl-lysine modification to peptidyl-hypusine K00809 - 2.5.1.46 3.716e-201 634.0
HFD2_k127_7850819_2 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009851 405.0
HFD2_k127_7850819_3 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 388.0
HFD2_k127_7850819_4 macromolecule localization K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 359.0
HFD2_k127_7850819_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000001631 204.0
HFD2_k127_7850819_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000299 209.0
HFD2_k127_7850819_8 protein import - - - 0.000000000000000000000000000000000000000000000000000002908 196.0
HFD2_k127_7865165_0 transport - - - 0.0 1193.0
HFD2_k127_7865165_1 PIN domain - - - 0.0000000000000000000000000004175 119.0
HFD2_k127_7865165_2 - - - - 0.0000001776 59.0
HFD2_k127_7891951_0 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 572.0
HFD2_k127_7891951_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 317.0
HFD2_k127_7897013_0 PA domain - - - 4.394e-201 638.0
HFD2_k127_7897013_1 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 534.0
HFD2_k127_7897013_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 350.0
HFD2_k127_7897013_3 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001068 280.0
HFD2_k127_7923465_0 Belongs to the IlvD Edd family - - - 2.541e-288 893.0
HFD2_k127_7923465_1 3-demethylubiquinone-9 3-O-methyltransferase activity K07011,K20444 - - 3.068e-199 638.0
HFD2_k127_7923465_2 Oxidoreductase - - - 0.000000000000000000000000000000000001093 143.0
HFD2_k127_7934403_0 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 338.0
HFD2_k127_7934403_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000009121 189.0
HFD2_k127_7935721_0 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 333.0
HFD2_k127_7935721_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 301.0
HFD2_k127_7935721_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009784 278.0
HFD2_k127_7935721_3 alginic acid biosynthetic process K01729 - 4.2.2.3 0.00000000000000000000000000000000000000000000000000000000000000000007841 252.0
HFD2_k127_7935721_4 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000001509 220.0
HFD2_k127_7935721_5 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000006735 164.0
HFD2_k127_7935721_6 Cell wall-active antibiotics response 4TMS YvqF - - - 0.0000000000000000000000000000000000003129 149.0
HFD2_k127_7935721_7 Glycosyl transferase, family 2 - - - 0.000000000000000000001749 104.0
HFD2_k127_7939890_0 PFAM Organic solvent tolerance protein K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 580.0
HFD2_k127_7939890_1 pfam rdd - - - 0.000007811 56.0
HFD2_k127_7948081_0 electron transfer activity K02305,K08738 - - 0.0 1182.0
HFD2_k127_7948081_1 efflux transmembrane transporter activity K12340 - - 8.345e-216 691.0
HFD2_k127_7948081_11 Histidine kinase K11617 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000001723 249.0
HFD2_k127_7948081_12 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000001953 242.0
HFD2_k127_7948081_13 MafB19-like deaminase - - - 0.00000000000000000000000000000000000000000000000000000000003451 209.0
HFD2_k127_7948081_14 HDOD domain - - - 0.00000000000000000000000000000000000000000000001857 183.0
HFD2_k127_7948081_15 efflux transmembrane transporter activity - - - 0.0000000000000001061 92.0
HFD2_k127_7948081_17 pfam abc K02003 - - 0.0000000003685 64.0
HFD2_k127_7948081_2 PFAM delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 544.0
HFD2_k127_7948081_3 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006016 460.0
HFD2_k127_7948081_4 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 456.0
HFD2_k127_7948081_5 1-deoxy-D-xylulose-5-phosphate synthase K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 398.0
HFD2_k127_7948081_6 response regulator K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 358.0
HFD2_k127_7948081_7 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 363.0
HFD2_k127_7948081_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 299.0
HFD2_k127_7948081_9 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001804 278.0
HFD2_k127_7956465_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 535.0
HFD2_k127_7956465_1 helix_turn_helix gluconate operon transcriptional repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 420.0
HFD2_k127_7958854_0 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 481.0
HFD2_k127_7958854_1 response to cobalt ion - - - 0.0000000000000000003095 93.0
HFD2_k127_7958854_2 periplasmic protein - - - 0.000000000188 72.0
HFD2_k127_7965052_0 lipopolysaccharide transport K04744 - - 0.0 1572.0
HFD2_k127_7965052_1 Carboxypeptidase regulatory-like domain - - - 0.0 1076.0
HFD2_k127_7965052_10 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 389.0
HFD2_k127_7965052_11 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 370.0
HFD2_k127_7965052_12 AhpC/TSA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007046 301.0
HFD2_k127_7965052_13 FMN binding K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 293.0
HFD2_k127_7965052_14 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 291.0
HFD2_k127_7965052_15 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000218 257.0
HFD2_k127_7965052_16 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002506 252.0
HFD2_k127_7965052_19 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000000000001262 115.0
HFD2_k127_7965052_2 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 6.583e-274 859.0
HFD2_k127_7965052_20 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000004347 92.0
HFD2_k127_7965052_21 PQQ-like domain - - - 0.000000000007649 79.0
HFD2_k127_7965052_22 cytochrome C family protein - - - 0.0000737 55.0
HFD2_k127_7965052_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 1.378e-207 656.0
HFD2_k127_7965052_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 490.0
HFD2_k127_7965052_5 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 467.0
HFD2_k127_7965052_6 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008708 481.0
HFD2_k127_7965052_7 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 461.0
HFD2_k127_7965052_8 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 471.0
HFD2_k127_7965052_9 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 422.0
HFD2_k127_7971245_0 domain protein - - - 8.927e-255 827.0
HFD2_k127_7971245_1 Pyridoxal-dependent decarboxylase conserved domain - - - 3.083e-238 743.0
HFD2_k127_7971245_10 amine dehydrogenase activity K12287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001486 280.0
HFD2_k127_7971245_11 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000009002 219.0
HFD2_k127_7971245_12 oxidation-reduction process K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000000000000000002361 211.0
HFD2_k127_7971245_13 COG0438 Glycosyltransferase - - - 0.00000000000000000000000000000000000000001098 156.0
HFD2_k127_7971245_14 Belongs to the glycosyl hydrolase 1 family - - - 0.000000000000000000000000000000000000122 148.0
HFD2_k127_7971245_15 - - - - 0.000000000000000000000000009044 126.0
HFD2_k127_7971245_17 - - - - 0.000000000000358 78.0
HFD2_k127_7971245_18 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000001591 65.0
HFD2_k127_7971245_19 Cytochrome c - - - 0.0000000162 64.0
HFD2_k127_7971245_2 alpha beta - - - 5.117e-205 661.0
HFD2_k127_7971245_3 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 618.0
HFD2_k127_7971245_4 Belongs to the glycosyl hydrolase 1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 598.0
HFD2_k127_7971245_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 567.0
HFD2_k127_7971245_6 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 560.0
HFD2_k127_7971245_7 Protein kinase domain K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 460.0
HFD2_k127_7971245_8 L-seryl-tRNASec selenium transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 438.0
HFD2_k127_7971245_9 carboxymethylenebutenolidase activity K01061,K06889 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002672 283.0
HFD2_k127_7986279_0 Glycosyl Hydrolase Family 88 K18581 - 3.2.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 589.0
HFD2_k127_7986279_1 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 332.0
HFD2_k127_7986279_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 295.0
HFD2_k127_7986279_3 HTH domain K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 298.0
HFD2_k127_8000205_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1102.0
HFD2_k127_8000205_1 TonB dependent receptor K16090 - - 6.272e-229 736.0
HFD2_k127_8000205_2 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 415.0
HFD2_k127_8000205_3 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 386.0
HFD2_k127_8000205_4 dimethylhistidine N-methyltransferase activity K18911 - 2.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 376.0
HFD2_k127_8000205_5 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009986 372.0
HFD2_k127_8000205_6 creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 287.0
HFD2_k127_8000205_7 Conserved hypothetical protein 95 - - - 0.00000000000000000000000000000000000000000000000001199 203.0
HFD2_k127_8000205_8 - - - - 0.0000000000000000000005121 100.0
HFD2_k127_8000205_9 Cysteine desulfurase K04487 - 2.8.1.7 0.0000000000000001835 80.0
HFD2_k127_8002251_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007512 356.0
HFD2_k127_8002251_1 PFAM Alcohol dehydrogenase GroES-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 337.0
HFD2_k127_8002251_2 Protein of unknown function (DUF3309) - - - 0.00000000000002261 74.0
HFD2_k127_8008055_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 1.183e-246 767.0
HFD2_k127_8008055_1 AsmA family K07289 - - 5.716e-228 738.0
HFD2_k127_8008055_10 Glycine cleavage H-protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008169 313.0
HFD2_k127_8008055_11 MobA-Related Protein K07141,K19190 - 1.1.1.328,2.7.7.76 0.000000000000000000000000000000000000000000000000000000000901 208.0
HFD2_k127_8008055_12 Peptidase family M54 K06974 - - 0.00000000000000000000000000000000000000000000000000000002893 218.0
HFD2_k127_8008055_13 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000003257 200.0
HFD2_k127_8008055_14 - - - - 0.00000000000000000000000000000000000000000000000000009776 194.0
HFD2_k127_8008055_15 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000000749 170.0
HFD2_k127_8008055_16 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000000000000000007144 161.0
HFD2_k127_8008055_17 - - - - 0.000000000000000000002773 104.0
HFD2_k127_8008055_18 Protein of unknown function (DUF433) - - - 0.00000000000000000002986 95.0
HFD2_k127_8008055_19 - - - - 0.00000000000000000003473 93.0
HFD2_k127_8008055_2 ATP:ADP antiporter activity K03301 - - 3.93e-226 733.0
HFD2_k127_8008055_20 DNA-templated transcription, initiation - - - 0.0000000000000000001413 95.0
HFD2_k127_8008055_21 - - - - 0.0000000000000000002387 92.0
HFD2_k127_8008055_23 sequence-specific DNA binding K18830 - - 0.000000000000002592 86.0
HFD2_k127_8008055_24 - - - - 0.00000001004 57.0
HFD2_k127_8008055_25 Protein of unknown function (DUF433) - - - 0.0000000489 56.0
HFD2_k127_8008055_26 Peptidase family M13 K01415 - 3.4.24.71 0.0000001125 60.0
HFD2_k127_8008055_27 peptidyl-tyrosine sulfation K15773 - - 0.000001669 53.0
HFD2_k127_8008055_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02482 - 2.7.13.3 4.579e-212 672.0
HFD2_k127_8008055_4 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 597.0
HFD2_k127_8008055_5 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 579.0
HFD2_k127_8008055_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 557.0
HFD2_k127_8008055_7 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009947 472.0
HFD2_k127_8008055_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 448.0
HFD2_k127_8008055_9 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006833 403.0
HFD2_k127_8028719_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 9.415e-213 672.0
HFD2_k127_8028719_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006976 432.0
HFD2_k127_8028719_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 391.0
HFD2_k127_8028719_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000001215 206.0
HFD2_k127_8028719_4 Cell division protein FtsQ K03589 - - 0.0000000000000000000000000000000000000000000002327 178.0
HFD2_k127_8064838_0 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 383.0
HFD2_k127_8064838_1 Bacterial alpha-L-rhamnosidase C-terminal domain K05989 - 3.2.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 355.0
HFD2_k127_8071817_0 ASPIC and UnbV - - - 2.341e-264 831.0
HFD2_k127_8071817_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 502.0
HFD2_k127_8071817_2 Cytochrome c K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007898 503.0
HFD2_k127_8071817_3 FAD linked oxidases, C-terminal domain K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 494.0
HFD2_k127_8071817_4 H( )-stimulated, divalent metal cation uptake system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 458.0
HFD2_k127_8071817_5 proline dipeptidase activity K08688 - 3.5.3.3 0.000000000000000000000000000000000000000000000005934 188.0
HFD2_k127_8071817_6 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000005344 113.0
HFD2_k127_8071817_7 PFAM PRC-barrel domain - - - 0.0000000000000000000000002265 113.0
HFD2_k127_8071817_8 - - - - 0.00000000000003115 76.0
HFD2_k127_8081832_0 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 579.0
HFD2_k127_8081832_1 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 537.0
HFD2_k127_8081832_2 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 490.0
HFD2_k127_8081832_3 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 306.0
HFD2_k127_8081832_4 Cytochrome c K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000004153 237.0
HFD2_k127_8081832_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000116 64.0
HFD2_k127_8122423_0 zinc D-Ala-D-Ala carboxypeptidase activity K08641 - 3.4.13.22 3.438e-256 811.0
HFD2_k127_8122423_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 9.012e-201 642.0
HFD2_k127_8122423_2 Protein of unknown function (DUF763) K09003 - - 2.218e-197 642.0
HFD2_k127_8122423_3 L-seryl-tRNASec selenium transferase activity K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 404.0
HFD2_k127_8122423_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 0.000000000000000000001758 108.0
HFD2_k127_8122423_5 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - - 0.000000000000004234 85.0
HFD2_k127_8137953_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0 1367.0
HFD2_k127_8137953_1 domain, Protein K11045 - - 0.0 1320.0
HFD2_k127_8137953_10 PFAM oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 304.0
HFD2_k127_8137953_11 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 289.0
HFD2_k127_8137953_12 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 285.0
HFD2_k127_8137953_13 Gluconate 2-dehydrogenase K06152 - 1.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001003 289.0
HFD2_k127_8137953_14 Phosphoribosyl transferase domain K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000003903 263.0
HFD2_k127_8137953_16 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.000000000000000000000000000000000000000000000000000000000000000138 229.0
HFD2_k127_8137953_17 amine dehydrogenase activity - - - 0.000000000000000000000008754 112.0
HFD2_k127_8137953_18 - - - - 0.00000000000000000000001077 108.0
HFD2_k127_8137953_19 Methane oxygenase PmoA - - - 0.00000000000000000000003662 115.0
HFD2_k127_8137953_2 Belongs to the TPP enzyme family K00156,K00158 - 1.2.3.3,1.2.5.1 8.837e-315 973.0
HFD2_k127_8137953_3 GMC oxidoreductase K06151 - 1.1.99.3 2.336e-246 774.0
HFD2_k127_8137953_4 4Fe-4S dicluster domain K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 431.0
HFD2_k127_8137953_5 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 411.0
HFD2_k127_8137953_7 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 348.0
HFD2_k127_8137953_8 Mandelate racemase muconate lactonizing enzyme K19802 - 5.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005693 344.0
HFD2_k127_8137953_9 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 314.0
HFD2_k127_813937_0 Oligoendopeptidase f - - - 9.067e-257 810.0
HFD2_k127_813937_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 526.0
HFD2_k127_813937_3 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000001233 175.0
HFD2_k127_813937_4 methyltransferase - - - 0.0000000000000000000008823 96.0
HFD2_k127_8144165_0 Domain of unknown function (DUF4976) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 473.0
HFD2_k127_8144165_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 422.0
HFD2_k127_8144165_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 409.0
HFD2_k127_8144165_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008017 376.0
HFD2_k127_815820_0 regulation of response to stimulus - - - 2.579e-286 891.0
HFD2_k127_815820_1 heat shock protein 70 K04043,K04044 - - 7.648e-266 831.0
HFD2_k127_815820_10 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 486.0
HFD2_k127_815820_11 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 362.0
HFD2_k127_815820_12 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 296.0
HFD2_k127_815820_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002781 282.0
HFD2_k127_815820_15 protein kinase activity K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003988 302.0
HFD2_k127_815820_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006748 272.0
HFD2_k127_815820_17 Rieske [2Fe-2S] domain K03886 - - 0.00000000000000000000000000000000000000000000000000000000000000000006185 234.0
HFD2_k127_815820_18 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000002565 230.0
HFD2_k127_815820_19 peptidyl-prolyl cis-trans isomerase activity K03769,K03770,K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000001421 207.0
HFD2_k127_815820_2 Cytochrome b(C-terminal)/b6/petD K00412 - - 1.037e-263 829.0
HFD2_k127_815820_20 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000001286 206.0
HFD2_k127_815820_21 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000007027 197.0
HFD2_k127_815820_22 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000005628 180.0
HFD2_k127_815820_23 ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.000000000000000000000000000000000000000000000002707 175.0
HFD2_k127_815820_24 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000001534 176.0
HFD2_k127_815820_25 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000000000000002518 170.0
HFD2_k127_815820_26 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000002357 166.0
HFD2_k127_815820_27 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000004243 161.0
HFD2_k127_815820_28 PFAM heat shock protein DnaJ K04082 - - 0.00000000000000000000000000000000000001106 151.0
HFD2_k127_815820_29 Cell division protein ZapA K09888 - - 0.00000000000000000000000000000000003773 136.0
HFD2_k127_815820_3 oligopeptidase that cleaves peptide bonds following arginine and lysine residues K01354 - 3.4.21.83 4.131e-263 832.0
HFD2_k127_815820_30 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000000006286 102.0
HFD2_k127_815820_33 FeS assembly protein IscX - - - 0.000000000000000000000328 97.0
HFD2_k127_815820_34 - - - - 0.0000000000000000003326 90.0
HFD2_k127_815820_35 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system K19166 - - 0.00000000000000003386 83.0
HFD2_k127_815820_36 Protein of unknown function (DUF3079) - - - 0.0000000000000003913 91.0
HFD2_k127_815820_37 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000003799 61.0
HFD2_k127_815820_38 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000788 59.0
HFD2_k127_815820_4 MacB-like periplasmic core domain - - - 7.374e-222 717.0
HFD2_k127_815820_5 efflux transmembrane transporter activity - - - 9.257e-217 700.0
HFD2_k127_815820_6 TIGRFAM exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 1.386e-212 668.0
HFD2_k127_815820_7 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 6.859e-203 637.0
HFD2_k127_815820_8 Belongs to the beta-ketoacyl-ACP synthases family K14660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 585.0
HFD2_k127_815820_9 electron transfer activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009701 526.0
HFD2_k127_8180557_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 7.07e-322 1002.0
HFD2_k127_8180557_1 PFAM Type II secretion system protein E K02652 - - 1.334e-306 944.0
HFD2_k127_8180557_10 type II secretion system K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 568.0
HFD2_k127_8180557_11 cell adhesion involved in biofilm formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 551.0
HFD2_k127_8180557_12 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 432.0
HFD2_k127_8180557_13 PFAM Uncharacterised BCR, COG1649 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 419.0
HFD2_k127_8180557_14 copper resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 415.0
HFD2_k127_8180557_15 Pilus assembly protein K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008018 371.0
HFD2_k127_8180557_16 PFAM ribonuclease K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 369.0
HFD2_k127_8180557_17 domain, Protein K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 373.0
HFD2_k127_8180557_18 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 354.0
HFD2_k127_8180557_19 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 310.0
HFD2_k127_8180557_2 O-methyltransferase activity - - - 1.193e-265 834.0
HFD2_k127_8180557_20 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009471 300.0
HFD2_k127_8180557_21 outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001106 286.0
HFD2_k127_8180557_22 FtsZ-dependent cytokinesis K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002744 274.0
HFD2_k127_8180557_23 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003696 263.0
HFD2_k127_8180557_24 - - - - 0.00000000000000000000000000000000000000000000000000000303 211.0
HFD2_k127_8180557_25 PFAM Fimbrial assembly family protein K02663 - - 0.00000000000000000000000000000000000000000000000000000452 196.0
HFD2_k127_8180557_26 Zincin-like metallopeptidase - - - 0.0000000000000000000000000000000000000000000000006059 180.0
HFD2_k127_8180557_27 - - - - 0.000000000000000000000000000000000000001391 163.0
HFD2_k127_8180557_28 domain, Protein - - - 0.0000000000003344 84.0
HFD2_k127_8180557_29 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000004202 77.0
HFD2_k127_8180557_3 Peptidase M16 - - - 6.628e-239 753.0
HFD2_k127_8180557_4 peptidylprolyl isomerase K03770 - 5.2.1.8 1.779e-233 739.0
HFD2_k127_8180557_5 peptidyl-tyrosine sulfation - - - 7.2e-230 737.0
HFD2_k127_8180557_6 Amino acid kinase family K00928 - 2.7.2.4 1.74e-215 689.0
HFD2_k127_8180557_7 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 2.46e-210 657.0
HFD2_k127_8180557_8 Carboxypeptidase regulatory-like domain - - - 1.632e-201 670.0
HFD2_k127_8180557_9 PFAM Neutral alkaline nonlysosomal ceramidase - - - 1.827e-200 638.0
HFD2_k127_8180571_0 Male sterility protein K12454 - 5.1.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 534.0
HFD2_k127_8180571_1 Pectate lyase K21606 - 3.2.1.202 0.0000000002739 66.0
HFD2_k127_8180571_2 positive regulation of growth K18829 - - 0.0000006516 51.0
HFD2_k127_8197471_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0 1067.0
HFD2_k127_8197471_1 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 1.037e-245 774.0
HFD2_k127_8197471_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 9.1e-205 647.0
HFD2_k127_8197471_3 Aminotransferase K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 586.0
HFD2_k127_8197471_4 GHMP kinases N terminal domain K07031 - 2.7.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 430.0
HFD2_k127_8197471_5 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 397.0
HFD2_k127_8197471_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 324.0
HFD2_k127_8197471_7 peptide deformylase activity K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000005196 182.0
HFD2_k127_8197471_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000005097 119.0
HFD2_k127_8206207_0 transport - - - 6.625e-253 817.0
HFD2_k127_8206207_1 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 7.439e-211 666.0
HFD2_k127_8206207_2 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 331.0
HFD2_k127_8206207_3 Major facilitator Superfamily K02511,K02575,K13021 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 332.0
HFD2_k127_8206207_4 TIGRFAM gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000007235 262.0
HFD2_k127_8206207_5 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000001151 222.0
HFD2_k127_8231703_0 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 362.0
HFD2_k127_8231703_1 Cytochrome c K00117 - 1.1.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 327.0
HFD2_k127_8258245_0 Carboxypeptidase regulatory-like domain - - - 0.0 1039.0
HFD2_k127_8258245_1 crispr-associated protein K07016 - - 3.288e-216 689.0
HFD2_k127_8258245_10 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007478 292.0
HFD2_k127_8258245_11 Met-10+ like-protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005898 266.0
HFD2_k127_8258245_12 with different specificities (related to short-chain alcohol K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000004554 190.0
HFD2_k127_8258245_13 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 GO:0001558,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0022607,GO:0030308,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0042802,GO:0042803,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044877,GO:0045926,GO:0046483,GO:0046700,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051259,GO:0051291,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000001092 144.0
HFD2_k127_8258245_15 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000008927 146.0
HFD2_k127_8258245_16 amine dehydrogenase activity - - - 0.000000000000000000000003976 121.0
HFD2_k127_8258245_17 - - - - 0.00000000000000000000003396 111.0
HFD2_k127_8258245_18 Transcriptional regulator antitoxin, MazE K07172 - - 0.000000000000000002917 86.0
HFD2_k127_8258245_19 SNARE associated Golgi protein - - - 0.000000000000007433 81.0
HFD2_k127_8258245_2 Glycosyl hydrolase family 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 623.0
HFD2_k127_8258245_3 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 550.0
HFD2_k127_8258245_4 cobalamin-transporting ATPase activity K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 512.0
HFD2_k127_8258245_5 - K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 508.0
HFD2_k127_8258245_6 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 481.0
HFD2_k127_8258245_7 PKD domain containing protein K01337,K20276,K21449 - 3.4.21.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 486.0
HFD2_k127_8258245_8 converts alpha-aldose to the beta-anomer - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 445.0
HFD2_k127_8258245_9 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 372.0
HFD2_k127_8260691_0 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 310.0
HFD2_k127_8260691_1 Participates in transcription elongation, termination and antitermination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007283 298.0
HFD2_k127_8260691_2 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000003507 219.0
HFD2_k127_8260691_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000003235 208.0
HFD2_k127_8260691_5 Domain of unknown function (DUF362) - - - 0.00000000000001159 88.0
HFD2_k127_8260691_6 Carboxypeptidase regulatory-like domain - - - 0.00000000004607 67.0
HFD2_k127_8260812_0 COG3119 Arylsulfatase A K01138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007635 526.0
HFD2_k127_8260812_1 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 404.0
HFD2_k127_8260812_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000399 195.0
HFD2_k127_8260812_3 COG COG3119 Arylsulfatase A and related enzymes - - - 0.0000000000000000000000000000000000000001003 157.0
HFD2_k127_8266629_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 8.93e-244 756.0
HFD2_k127_8266629_1 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 382.0
HFD2_k127_8289791_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1846.0
HFD2_k127_8289791_1 DNA-K related protein - - - 0.0 1454.0
HFD2_k127_8289791_10 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 2.032e-209 659.0
HFD2_k127_8289791_11 Biotin-lipoyl like K02005 - - 5.475e-203 641.0
HFD2_k127_8289791_12 Histidine kinase internal region K02478 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 610.0
HFD2_k127_8289791_13 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 591.0
HFD2_k127_8289791_14 Oligogalacturonate lyase K01730 - 4.2.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 578.0
HFD2_k127_8289791_15 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 531.0
HFD2_k127_8289791_16 ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008872 508.0
HFD2_k127_8289791_17 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 522.0
HFD2_k127_8289791_18 L-fucose isomerase and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 501.0
HFD2_k127_8289791_19 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 495.0
HFD2_k127_8289791_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1335.0
HFD2_k127_8289791_20 PFAM Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 485.0
HFD2_k127_8289791_21 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 449.0
HFD2_k127_8289791_22 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 451.0
HFD2_k127_8289791_23 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 431.0
HFD2_k127_8289791_24 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 411.0
HFD2_k127_8289791_25 MreB/Mbl protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 401.0
HFD2_k127_8289791_26 Belongs to the MlaE permease family K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007164 402.0
HFD2_k127_8289791_27 Glycosyl transferase, family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 404.0
HFD2_k127_8289791_28 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 394.0
HFD2_k127_8289791_29 PFAM ABC transporter K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 398.0
HFD2_k127_8289791_3 cell adhesion involved in biofilm formation K13735,K20276 - - 0.0 1245.0
HFD2_k127_8289791_30 Peptidase family S58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009587 389.0
HFD2_k127_8289791_31 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 384.0
HFD2_k127_8289791_32 PFAM ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 378.0
HFD2_k127_8289791_33 PFAM YdjC family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 363.0
HFD2_k127_8289791_34 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005879 359.0
HFD2_k127_8289791_35 PFAM Rhomboid family K19225 - 3.4.21.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 355.0
HFD2_k127_8289791_36 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 362.0
HFD2_k127_8289791_37 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 359.0
HFD2_k127_8289791_38 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 349.0
HFD2_k127_8289791_39 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 364.0
HFD2_k127_8289791_4 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503,K13950 - 2.6.1.85,4.1.3.27 0.0 1128.0
HFD2_k127_8289791_40 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 335.0
HFD2_k127_8289791_41 - K06862 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005139 331.0
HFD2_k127_8289791_42 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 324.0
HFD2_k127_8289791_43 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 318.0
HFD2_k127_8289791_44 Catalyzes the synthesis of activated sulfate K00390,K00860 - 1.8.4.10,1.8.4.8,2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 311.0
HFD2_k127_8289791_45 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 312.0
HFD2_k127_8289791_46 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 305.0
HFD2_k127_8289791_47 Molybdate ABC transporter K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001944 283.0
HFD2_k127_8289791_48 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004331 262.0
HFD2_k127_8289791_49 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000659 255.0
HFD2_k127_8289791_5 protocatechuate 3,4-dioxygenase activity - - - 8.551e-307 969.0
HFD2_k127_8289791_50 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002042 255.0
HFD2_k127_8289791_51 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005875 254.0
HFD2_k127_8289791_52 region 4 type 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000757 246.0
HFD2_k127_8289791_53 SMART PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000013 266.0
HFD2_k127_8289791_54 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.0000000000000000000000000000000000000000000000000000000000000000000111 252.0
HFD2_k127_8289791_55 adenylylsulfate kinase activity K00390,K00860,K00958 GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564 1.8.4.10,1.8.4.8,2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000192 239.0
HFD2_k127_8289791_56 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000003973 227.0
HFD2_k127_8289791_57 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000000000000000000000001247 215.0
HFD2_k127_8289791_58 methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000004762 215.0
HFD2_k127_8289791_59 PFAM thiamine monophosphate synthase K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000002567 208.0
HFD2_k127_8289791_6 Ferrous iron transport protein B K04759 - - 1.368e-283 887.0
HFD2_k127_8289791_60 PFAM response regulator receiveR - - - 0.00000000000000000000000000000000000000000000000000001878 192.0
HFD2_k127_8289791_62 - - - - 0.0000000000000000000000000000000000000000000000000001698 193.0
HFD2_k127_8289791_63 metal-binding protein - - - 0.0000000000000000000000000000000000000000000000000005938 191.0
HFD2_k127_8289791_64 regulatory protein, MerR - - - 0.000000000000000000000000000000000000000000000002011 176.0
HFD2_k127_8289791_65 Domain of unknown function (DUF892) - - - 0.000000000000000000000000000000000000000000000008761 177.0
HFD2_k127_8289791_66 HDOD domain - - - 0.000000000000000000000000000000000000000000000178 181.0
HFD2_k127_8289791_67 PFAM Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000001537 173.0
HFD2_k127_8289791_68 ethanolamine catabolic process K04027 - - 0.000000000000000000000000000000000000000000002569 165.0
HFD2_k127_8289791_69 - - - - 0.000000000000000000000000000000000000000000003111 178.0
HFD2_k127_8289791_7 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 1.926e-277 872.0
HFD2_k127_8289791_70 HDOD domain - - - 0.000000000000000000000000000000000000000000003344 174.0
HFD2_k127_8289791_71 Disulphide bond corrector protein DsbC - - - 0.00000000000000000000000000000000000000000005312 166.0
HFD2_k127_8289791_72 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.0000000000000000000000000000000000000000002318 159.0
HFD2_k127_8289791_73 YjbR - - - 0.0000000000000000000000000000000000000000005612 161.0
HFD2_k127_8289791_74 - - - - 0.000000000000000000000000000000000000000003278 164.0
HFD2_k127_8289791_75 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.0000000000000000000000000000000000000007284 154.0
HFD2_k127_8289791_76 Glyoxalase-like domain K05606 - 5.1.99.1 0.00000000000000000000000000000000000174 145.0
HFD2_k127_8289791_78 Anti-sigma factor - - - 0.00000000000000000000000000000000003999 149.0
HFD2_k127_8289791_79 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.0000000000000000000000000000000001227 137.0
HFD2_k127_8289791_8 - - - - 9.555e-252 801.0
HFD2_k127_8289791_80 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07716 - 2.7.13.3 0.0000000000000000000000000000000035 149.0
HFD2_k127_8289791_81 response regulator K02479,K07684,K07685 - - 0.0000000000000000000000000000001559 131.0
HFD2_k127_8289791_82 - - - - 0.0000000000000000000000000189 116.0
HFD2_k127_8289791_83 FeoA K04758 - - 0.00000000000000000000000003145 115.0
HFD2_k127_8289791_84 permease K03548 - - 0.0000000000000000000000001246 111.0
HFD2_k127_8289791_85 - - - - 0.000000000000000000000001252 110.0
HFD2_k127_8289791_86 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000006577 105.0
HFD2_k127_8289791_87 Metallo-beta-lactamase superfamily - - - 0.000000000000000002278 100.0
HFD2_k127_8289791_88 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000000001239 75.0
HFD2_k127_8289791_9 PFAM Uncharacterised BCR, COG1649 - - - 1.211e-222 701.0
HFD2_k127_8289791_91 Stage II sporulation protein E (SpoIIE) K07315 - 3.1.3.3 0.0001815 45.0
HFD2_k127_8291910_0 Carboxypeptidase regulatory-like domain - - - 2.978e-194 652.0
HFD2_k127_8291910_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351 446.0
HFD2_k127_8291910_2 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 445.0
HFD2_k127_8291910_3 transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000004275 246.0
HFD2_k127_8291910_4 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001563 226.0
HFD2_k127_8301099_0 efflux transmembrane transporter activity - - - 3.47e-276 878.0
HFD2_k127_8301099_1 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004548 327.0
HFD2_k127_8301099_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000006077 226.0
HFD2_k127_8301099_3 Acyl dehydratase - - - 0.00000000000000000000000000000000000000000000001452 181.0
HFD2_k127_8301099_4 Phosphoglycerate mutase family - - - 0.000000000000000000000000001052 123.0
HFD2_k127_8301099_5 DUF218 domain - - - 0.000000000001531 79.0
HFD2_k127_8301099_6 negative regulation of transcription, DNA-templated - - - 0.0000007732 52.0
HFD2_k127_8304009_0 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 2.815e-204 642.0
HFD2_k127_8304009_1 Glucose inhibited division protein A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005884 268.0
HFD2_k127_8304009_2 TIGRFAM methyltransferase FkbM - - - 0.0000000000000000000001311 110.0
HFD2_k127_8304009_3 DDE superfamily endonuclease - - - 0.0000000002351 61.0
HFD2_k127_8316429_0 protocatechuate 3,4-dioxygenase activity - - - 4.287e-296 945.0
HFD2_k127_8316429_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 2.591e-256 805.0
HFD2_k127_8316429_10 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 306.0
HFD2_k127_8316429_11 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000006052 185.0
HFD2_k127_8316429_12 Probable zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000000000001351 180.0
HFD2_k127_8316429_13 - - - - 0.00000000000000000000000000000000000000000343 162.0
HFD2_k127_8316429_14 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000000000003997 115.0
HFD2_k127_8316429_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 4.531e-222 696.0
HFD2_k127_8316429_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.276e-216 677.0
HFD2_k127_8316429_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 1.062e-200 634.0
HFD2_k127_8316429_5 arylsulfatase activity K01138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 623.0
HFD2_k127_8316429_6 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 504.0
HFD2_k127_8316429_7 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 477.0
HFD2_k127_8316429_8 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 419.0
HFD2_k127_8316429_9 dehydrogenases and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 384.0
HFD2_k127_8320843_0 TonB-dependent receptor - - - 0.0 1360.0
HFD2_k127_8320843_1 Cytochrome c - - - 2.554e-237 765.0
HFD2_k127_8320843_10 - - - - 0.00000000000000000000000000000000000000000000000004688 203.0
HFD2_k127_8320843_11 TonB-dependent receptor - - - 0.00000000000000000000000000000000001882 138.0
HFD2_k127_8320843_12 PFAM RhaT l-rhamnose-proton symport 2 K02856 - - 0.0000000000000000000000000002926 124.0
HFD2_k127_8320843_13 FCD - - - 0.000000000000000000000000895 112.0
HFD2_k127_8320843_14 L-rhamnose-proton symport protein (RhaT) - - - 0.00000000000000000002531 93.0
HFD2_k127_8320843_15 Belongs to the 'phage' integrase family K07484 - - 0.00000000000000000006258 92.0
HFD2_k127_8320843_16 - - - - 0.00000000000003051 87.0
HFD2_k127_8320843_17 PFAM Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000001269 64.0
HFD2_k127_8320843_18 TonB-dependent receptor - - - 0.00000001525 57.0
HFD2_k127_8320843_19 TonB-dependent receptor - - - 0.000000172 61.0
HFD2_k127_8320843_2 Hypothetical glycosyl hydrolase 6 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 614.0
HFD2_k127_8320843_20 Anabaena sensory rhodopsin transducer - - - 0.000009252 51.0
HFD2_k127_8320843_3 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009109 584.0
HFD2_k127_8320843_4 beta-galactosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005639 572.0
HFD2_k127_8320843_5 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 531.0
HFD2_k127_8320843_6 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 505.0
HFD2_k127_8320843_7 Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 400.0
HFD2_k127_8320843_8 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004201 251.0
HFD2_k127_8320843_9 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000007063 246.0
HFD2_k127_8348517_0 Phosphoesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 610.0
HFD2_k127_8348517_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006183 558.0
HFD2_k127_8348517_10 PFAM Abortive infection protein K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000001014 242.0
HFD2_k127_8348517_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000001647 225.0
HFD2_k127_8348517_12 - - - - 0.000000000000000000000000000000000000000003039 168.0
HFD2_k127_8348517_13 cell redox homeostasis - - - 0.0000000000000000000000000000001483 132.0
HFD2_k127_8348517_2 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 545.0
HFD2_k127_8348517_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 524.0
HFD2_k127_8348517_4 PFAM Abortive infection protein K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 387.0
HFD2_k127_8348517_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008778 369.0
HFD2_k127_8348517_6 short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 345.0
HFD2_k127_8348517_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002421 288.0
HFD2_k127_8348517_8 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001795 250.0
HFD2_k127_8348517_9 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000005049 261.0
HFD2_k127_8381378_0 Bacterial Peptidase A24 N-terminal domain K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 348.0
HFD2_k127_8381378_1 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 324.0
HFD2_k127_8381378_10 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000001149 76.0
HFD2_k127_8381378_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000298 221.0
HFD2_k127_8381378_3 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000000000013 188.0
HFD2_k127_8381378_4 FMN binding K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000007628 181.0
HFD2_k127_8381378_5 tRNA methyltransferase complex GCD14 subunit - - - 0.0000000000000000000000000000007841 130.0
HFD2_k127_8381378_6 Zinc-binding dehydrogenase - - - 0.000000000000000000000000004964 116.0
HFD2_k127_8381378_7 COG2346, Truncated hemoglobins K06886 - - 0.00000000000000005126 87.0
HFD2_k127_8381378_8 - - - - 0.00000000000000009476 84.0
HFD2_k127_8381378_9 Protein of unknown function (DUF433) - - - 0.00000000000002181 77.0
HFD2_k127_8383985_0 Voltage gated chloride channel - - - 3.866e-238 760.0
HFD2_k127_8383985_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 469.0
HFD2_k127_8383985_2 Histidine kinase K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 370.0
HFD2_k127_8383985_3 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 299.0
HFD2_k127_8383985_4 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000000000000000000000001094 163.0
HFD2_k127_8383985_5 MarR family - - - 0.0000000000000000000000000000000002467 136.0
HFD2_k127_8383985_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000006644 119.0
HFD2_k127_8383985_7 - - - - 0.0000001147 61.0
HFD2_k127_8396640_0 amine dehydrogenase activity - - - 0.0 1201.0
HFD2_k127_8396640_1 ATP-dependent DNA helicase activity K01144,K16898 - 3.1.11.5,3.6.4.12 1.821e-279 897.0
HFD2_k127_8396640_10 type II secretion system K12510 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 444.0
HFD2_k127_8396640_11 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 443.0
HFD2_k127_8396640_12 type II secretion system K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 416.0
HFD2_k127_8396640_13 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 427.0
HFD2_k127_8396640_14 Flp pilus assembly protein CpaB K02279 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 380.0
HFD2_k127_8396640_15 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 377.0
HFD2_k127_8396640_16 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 337.0
HFD2_k127_8396640_17 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000257 293.0
HFD2_k127_8396640_19 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000000000000000000000006081 182.0
HFD2_k127_8396640_2 exonuclease activity K16899 - 3.6.4.12 1.094e-256 817.0
HFD2_k127_8396640_20 PFAM TadE family protein - - - 0.00000000000000000000000000000000000000000005777 166.0
HFD2_k127_8396640_21 Flp Fap pilin component K02651 - - 0.0000000000000000001231 93.0
HFD2_k127_8396640_3 PFAM type II secretion system protein E K02283 - - 8.973e-243 754.0
HFD2_k127_8396640_4 Putative modulator of DNA gyrase K03568 - - 2.587e-231 733.0
HFD2_k127_8396640_5 AAA domain K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 600.0
HFD2_k127_8396640_6 Belongs to the GSP D family K02280 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 587.0
HFD2_k127_8396640_7 Putative modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 497.0
HFD2_k127_8396640_8 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 503.0
HFD2_k127_8396640_9 metallocarboxypeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 463.0
HFD2_k127_8445348_0 Carboxypeptidase regulatory-like domain - - - 0.0 1140.0
HFD2_k127_8445348_1 Carboxypeptidase regulatory-like domain - - - 0.0 1042.0
HFD2_k127_8445348_2 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 612.0
HFD2_k127_8445348_3 Amino acid permease K16238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 495.0
HFD2_k127_8445348_4 denitrification pathway - - - 0.000000000001102 75.0
HFD2_k127_8445348_5 Cytochrome c K00406,K08906 - - 0.0000001698 57.0
HFD2_k127_8447866_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.547e-230 723.0
HFD2_k127_8447866_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 491.0
HFD2_k127_8447866_2 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009123 420.0
HFD2_k127_8447866_3 - K21449 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009857 424.0
HFD2_k127_8447866_4 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 392.0
HFD2_k127_845148_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 8.279e-312 962.0
HFD2_k127_845148_1 Carbamoyltransferase C-terminus K00612 - - 8.165e-248 776.0
HFD2_k127_845148_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 4.971e-213 672.0
HFD2_k127_845148_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 594.0
HFD2_k127_845148_4 PfkB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 524.0
HFD2_k127_845148_5 mandelate racemase muconate lactonizing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 502.0
HFD2_k127_845148_6 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 476.0
HFD2_k127_845148_7 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 398.0
HFD2_k127_845148_8 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000005254 252.0
HFD2_k127_8452891_0 Carboxypeptidase regulatory-like domain - - - 1.527e-263 846.0
HFD2_k127_8452891_1 protocatechuate 3,4-dioxygenase activity - - - 3.702e-247 803.0
HFD2_k127_8452891_10 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009952 302.0
HFD2_k127_8452891_11 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009087 269.0
HFD2_k127_8452891_12 Protein of unknown function (DUF692) K09930 - - 0.0000000000000000000000000000000000000000000000000001216 195.0
HFD2_k127_8452891_13 carboxylic acid catabolic process K01706 - 4.2.1.40 0.000000000000000000000000000000000000000000005285 177.0
HFD2_k127_8452891_14 DNA alkylation repair enzyme - - - 0.000000000008963 75.0
HFD2_k127_8452891_15 self proteolysis - - - 0.0008562 43.0
HFD2_k127_8452891_2 Carboxypeptidase regulatory-like domain - - - 9.938e-232 762.0
HFD2_k127_8452891_3 arylsulfatase activity - - - 1.698e-208 667.0
HFD2_k127_8452891_4 PFAM Acetyl xylan esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004622 500.0
HFD2_k127_8452891_5 Glycosyl hydrolase family 20, domain 2 K12373 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 480.0
HFD2_k127_8452891_6 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000879 385.0
HFD2_k127_8452891_7 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 387.0
HFD2_k127_8452891_8 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008004 316.0
HFD2_k127_8452891_9 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 309.0
HFD2_k127_8455170_0 - - - - 1.595e-221 694.0
HFD2_k127_8455170_1 phage Terminase large subunit - - - 1.851e-195 622.0
HFD2_k127_8455170_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000002804 232.0
HFD2_k127_8455170_11 - - - - 0.000000000000000000000000000000000000000000000000000000007152 209.0
HFD2_k127_8455170_12 - - - - 0.000000000000000000000000000000000000007225 152.0
HFD2_k127_8455170_13 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000003244 121.0
HFD2_k127_8455170_14 - - - - 0.00000000000002011 81.0
HFD2_k127_8455170_15 - - - - 0.000000000005273 68.0
HFD2_k127_8455170_16 Glyoxalase-like domain K08234 - - 0.000001086 54.0
HFD2_k127_8455170_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 592.0
HFD2_k127_8455170_3 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 509.0
HFD2_k127_8455170_4 P22 coat protein - gene protein 5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 498.0
HFD2_k127_8455170_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 486.0
HFD2_k127_8455170_6 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 389.0
HFD2_k127_8455170_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 330.0
HFD2_k127_8455170_8 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 325.0
HFD2_k127_8455170_9 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001884 278.0
HFD2_k127_8515060_0 zinc ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 614.0
HFD2_k127_8515060_1 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 312.0
HFD2_k127_8515060_2 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 317.0
HFD2_k127_8515111_0 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 1.853e-308 986.0
HFD2_k127_8515111_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 569.0
HFD2_k127_8515111_2 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 337.0
HFD2_k127_8515111_3 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 338.0
HFD2_k127_8537007_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 545.0
HFD2_k127_8537007_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 500.0
HFD2_k127_8537007_2 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 362.0
HFD2_k127_8537007_3 ATPase activity K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009249 337.0
HFD2_k127_8537007_4 Acid phosphatase homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 292.0
HFD2_k127_8537007_5 Serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.00000000000000000000000000000000000000000000000000000004023 220.0
HFD2_k127_8537007_6 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000007727 132.0
HFD2_k127_8537007_7 SAM-dependent methyltransferase - - - 0.000000000000000000000000000000007785 137.0
HFD2_k127_8537007_8 COG3278 Cbb3-type cytochrome oxidase, subunit 1 - - - 0.00000000000000000000000000003749 121.0
HFD2_k127_8537007_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000002317 84.0
HFD2_k127_8554112_0 Glutamate-ammonia ligase adenylyltransferase K00982 - 2.7.7.42,2.7.7.89 0.0 1184.0
HFD2_k127_8554112_1 glutamine synthetase K01915 GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 2.451e-289 890.0
HFD2_k127_8554112_10 C-terminal, D2-small domain, of ClpB protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 330.0
HFD2_k127_8554112_11 MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 331.0
HFD2_k127_8554112_12 Diphthamide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 315.0
HFD2_k127_8554112_13 PFAM NHL repeat containing protein K13735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 332.0
HFD2_k127_8554112_14 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 293.0
HFD2_k127_8554112_15 Outer membrane lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 293.0
HFD2_k127_8554112_16 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 290.0
HFD2_k127_8554112_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000004865 226.0
HFD2_k127_8554112_18 PFAM MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000001773 222.0
HFD2_k127_8554112_19 TIGRFAM TonB family K03832 - - 0.0000000000000000000000000000000000000000000000000000000001965 214.0
HFD2_k127_8554112_2 TonB-dependent Receptor Plug Domain K02014,K16092 - - 1.047e-238 758.0
HFD2_k127_8554112_20 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000000000000000000000000000001618 180.0
HFD2_k127_8554112_21 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000004011 167.0
HFD2_k127_8554112_22 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000001597 144.0
HFD2_k127_8554112_23 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000003105 117.0
HFD2_k127_8554112_3 May be involved in recombinational repair of damaged DNA K03631 - - 2.944e-225 711.0
HFD2_k127_8554112_4 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.015e-209 654.0
HFD2_k127_8554112_5 WD40-like Beta Propeller K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 589.0
HFD2_k127_8554112_6 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008383 447.0
HFD2_k127_8554112_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 426.0
HFD2_k127_8554112_8 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 424.0
HFD2_k127_8554112_9 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006586 370.0
HFD2_k127_8556633_0 Carboxypeptidase regulatory-like domain - - - 0.0 1190.0
HFD2_k127_8556633_1 histidine kinase HAMP region domain protein - - - 2.163e-225 719.0
HFD2_k127_8556633_10 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 364.0
HFD2_k127_8556633_11 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008614 364.0
HFD2_k127_8556633_12 arylsulfatase activity K01138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 361.0
HFD2_k127_8556633_13 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006388 273.0
HFD2_k127_8556633_15 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000007711 219.0
HFD2_k127_8556633_16 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000176 151.0
HFD2_k127_8556633_17 Cold shock protein domain K03704 - - 0.00000000000000000000000000000007777 125.0
HFD2_k127_8556633_2 cellulose binding - - - 2.486e-209 669.0
HFD2_k127_8556633_20 Domain of unknown function DUF302 - - - 0.000000000000000000000000001198 118.0
HFD2_k127_8556633_21 PFAM TPR repeat-containing protein - - - 0.00000000000000000000000005072 122.0
HFD2_k127_8556633_22 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000008361 106.0
HFD2_k127_8556633_24 Tetratricopeptide repeat - - - 0.0000000009086 66.0
HFD2_k127_8556633_25 subunit of a heme lyase K02200 - - 0.000000007427 67.0
HFD2_k127_8556633_26 - - - - 0.00000004305 66.0
HFD2_k127_8556633_27 peptidyl-tyrosine sulfation - - - 0.00008039 50.0
HFD2_k127_8556633_29 Hypothetical glycosyl hydrolase 6 - - - 0.0006192 51.0
HFD2_k127_8556633_3 PFAM oxidoreductase domain protein - - - 1.214e-204 646.0
HFD2_k127_8556633_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006709 536.0
HFD2_k127_8556633_5 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 455.0
HFD2_k127_8556633_6 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000829 455.0
HFD2_k127_8556633_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 449.0
HFD2_k127_8556633_8 PFAM response regulator receiver K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 403.0
HFD2_k127_8556633_9 Two component transcriptional regulator, winged helix family K07776 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 400.0
HFD2_k127_8604049_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1430.0
HFD2_k127_8604049_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1357.0
HFD2_k127_8604049_10 transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001166 284.0
HFD2_k127_8604049_11 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000003643 251.0
HFD2_k127_8604049_12 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000007927 226.0
HFD2_k127_8604049_13 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000005632 224.0
HFD2_k127_8604049_14 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000001018 169.0
HFD2_k127_8604049_15 Toxic component of a toxin-antitoxin (TA) module. An RNase K00640,K07062 - 2.3.1.30 0.0000000000000000000000000000000000000873 145.0
HFD2_k127_8604049_16 - - - - 0.00000000004878 73.0
HFD2_k127_8604049_2 FecR protein - - - 4.059e-201 657.0
HFD2_k127_8604049_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 518.0
HFD2_k127_8604049_4 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 479.0
HFD2_k127_8604049_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 352.0
HFD2_k127_8604049_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 329.0
HFD2_k127_8604049_7 DinB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 284.0
HFD2_k127_8604049_8 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008159 267.0
HFD2_k127_8604049_9 PFAM ATP-binding region, ATPase domain protein domain protein K07683 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001287 271.0
HFD2_k127_8607413_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.058e-262 813.0
HFD2_k127_8607413_1 calcium, potassium:sodium antiporter activity K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 473.0
HFD2_k127_8607413_2 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 314.0
HFD2_k127_8607413_3 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 306.0
HFD2_k127_8607413_4 Protein of unknown function (DUF418) K07148 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 304.0
HFD2_k127_8607413_5 WD domain, G-beta repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 316.0
HFD2_k127_8607413_6 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000001159 224.0
HFD2_k127_8607413_7 CHAT domain - - - 0.000000000000000000000000000005164 126.0
HFD2_k127_8607413_8 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.00000000000000000000002229 103.0
HFD2_k127_8613516_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2134.0
HFD2_k127_8613516_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1247.0
HFD2_k127_8613516_10 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001787 272.0
HFD2_k127_8613516_11 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001451 246.0
HFD2_k127_8613516_12 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000003862 222.0
HFD2_k127_8613516_13 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000000001858 188.0
HFD2_k127_8613516_14 addiction module antidote protein HigA K21498 - - 0.00000000000000000000000000000004419 127.0
HFD2_k127_8613516_15 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000006415 79.0
HFD2_k127_8613516_16 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.000000000007693 76.0
HFD2_k127_8613516_17 mRNA binding K07339 - - 0.0005311 42.0
HFD2_k127_8613516_2 Carboxypeptidase regulatory-like domain - - - 0.0 1176.0
HFD2_k127_8613516_3 DNA polymerase X K02347 - - 5.606e-296 917.0
HFD2_k127_8613516_4 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 3.759e-211 661.0
HFD2_k127_8613516_5 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 478.0
HFD2_k127_8613516_6 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009347 414.0
HFD2_k127_8613516_7 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 397.0
HFD2_k127_8613516_8 protocatechuate 3,4-dioxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 361.0
HFD2_k127_8613516_9 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 354.0
HFD2_k127_8638092_0 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 8.626e-196 613.0
HFD2_k127_8638092_1 deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K01635 - 4.1.2.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 554.0
HFD2_k127_8638092_10 N-acetylmuramidase - - - 0.00000000000000000000000000000000000000000000000000001181 197.0
HFD2_k127_8638092_11 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000001459 169.0
HFD2_k127_8638092_12 cheY-homologous receiver domain - - - 0.000000000000000000000000000004136 123.0
HFD2_k127_8638092_13 Domain of unknown function (DUF1844) - - - 0.000000000000000000000000003207 116.0
HFD2_k127_8638092_14 ABC transporter substrate-binding protein K01989 - - 0.000000000002872 78.0
HFD2_k127_8638092_15 Protein conserved in bacteria - - - 0.00000000002854 73.0
HFD2_k127_8638092_2 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006796 415.0
HFD2_k127_8638092_3 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006652 404.0
HFD2_k127_8638092_4 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 383.0
HFD2_k127_8638092_5 TIGRFAM MazG family protein K02428,K02499,K04765 - 3.6.1.66,3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 375.0
HFD2_k127_8638092_6 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 394.0
HFD2_k127_8638092_7 Esterase of the alpha-beta hydrolase superfamily K07001 GO:0003674,GO:0003824,GO:0016787 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 342.0
HFD2_k127_8638092_8 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006372 312.0
HFD2_k127_8638092_9 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000003278 214.0
HFD2_k127_8689147_0 SIR2-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 409.0
HFD2_k127_8689147_2 choline dehydrogenase activity K03333 - 1.1.3.6 0.00000000000000000000000000000000000001802 156.0
HFD2_k127_8689147_4 TPR repeat - - - 0.00003284 54.0
HFD2_k127_877484_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 6.248e-264 837.0
HFD2_k127_877484_1 DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 578.0
HFD2_k127_877484_10 Putative restriction endonuclease - - - 0.00000000000000000000000000000001258 133.0
HFD2_k127_877484_11 - - - - 0.00000000000000000000000005176 116.0
HFD2_k127_877484_2 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 423.0
HFD2_k127_877484_3 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 361.0
HFD2_k127_877484_4 ABC-type glycine betaine transport system K05845 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 359.0
HFD2_k127_877484_5 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007457 352.0
HFD2_k127_877484_6 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 325.0
HFD2_k127_877484_7 SMART ATPase, AAA type, core K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 308.0
HFD2_k127_877484_8 glycine betaine transport K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006242 246.0
HFD2_k127_877484_9 DinB family - - - 0.0000000000000000000000000000000000000001985 155.0
HFD2_k127_879555_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 414.0
HFD2_k127_879555_1 beta-galactosidase activity K12308 - 3.2.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 418.0
HFD2_k127_879555_2 IstB-like ATP binding protein K02315 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 330.0
HFD2_k127_879555_3 Biotin-requiring enzyme - - - 0.0000000000000000000000000000000000000000000000003392 192.0
HFD2_k127_882034_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1150.0
HFD2_k127_882034_1 phosphorelay sensor kinase activity K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 505.0
HFD2_k127_882034_2 PFAM Outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 400.0
HFD2_k127_882034_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 327.0
HFD2_k127_882034_4 serine-type peptidase activity K06978,K21105 - 3.1.1.102 0.0000000000007698 78.0
HFD2_k127_894332_0 amine dehydrogenase activity - - - 0.0 1088.0
HFD2_k127_894332_1 ATP:ADP antiporter activity K03301 - - 1.517e-245 787.0
HFD2_k127_894332_10 PFAM SMP-30 Gluconolaconase K08685 - 1.4.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 407.0
HFD2_k127_894332_11 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 346.0
HFD2_k127_894332_12 phosphoprotein phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 342.0
HFD2_k127_894332_13 transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 299.0
HFD2_k127_894332_14 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004457 265.0
HFD2_k127_894332_15 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000281 252.0
HFD2_k127_894332_16 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001463 267.0
HFD2_k127_894332_17 Protein of unknown function (DUF3485) - - - 0.000000000000000000000000000000000000000000000000000000000000001863 225.0
HFD2_k127_894332_18 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000381 219.0
HFD2_k127_894332_19 cyclic nucleotide binding K00384,K01999,K07001,K10914 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000002269 205.0
HFD2_k127_894332_2 Pyridoxal-phosphate dependent enzyme K06001 - 4.2.1.20 2.708e-205 643.0
HFD2_k127_894332_20 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000001137 211.0
HFD2_k127_894332_21 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000002142 205.0
HFD2_k127_894332_22 AhpC/TSA family - - - 0.0000000000000000000000000000000001735 151.0
HFD2_k127_894332_23 eight transmembrane protein EpsH - - - 0.000000000000000000002385 108.0
HFD2_k127_894332_24 PAS domain K13587 - 2.7.13.3 0.000000000000000005255 93.0
HFD2_k127_894332_25 ubiE/COQ5 methyltransferase family - - - 0.00000001507 66.0
HFD2_k127_894332_3 Nicotinate phosphoribosyltransferase (NAPRTase) family K00763 - 6.3.4.21 3.577e-204 647.0
HFD2_k127_894332_4 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 562.0
HFD2_k127_894332_5 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 537.0
HFD2_k127_894332_6 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 514.0
HFD2_k127_894332_7 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 502.0
HFD2_k127_894332_8 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 422.0
HFD2_k127_894332_9 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007379 418.0
HFD2_k127_897918_0 transport - - - 0.0 1074.0
HFD2_k127_897918_1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 3.545e-250 795.0
HFD2_k127_897918_2 TIGRFAM Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 314.0
HFD2_k127_897918_3 - - - - 0.000000000000000000000000000000000000000000000000000000000003839 213.0
HFD2_k127_897918_4 PFAM Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000000008486 203.0
HFD2_k127_921870_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1210.0
HFD2_k127_921870_1 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 613.0
HFD2_k127_921870_10 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004044 285.0
HFD2_k127_921870_11 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004234 267.0
HFD2_k127_921870_12 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002419 243.0
HFD2_k127_921870_13 Domain of unknown function (DUF2520) - - - 0.00000000000000000000000000000000000000000000000000000000005146 217.0
HFD2_k127_921870_14 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000004295 214.0
HFD2_k127_921870_15 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000000000000005495 150.0
HFD2_k127_921870_16 sequence-specific DNA binding - - - 0.00000000000000000000000000000000882 134.0
HFD2_k127_921870_17 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000008488 124.0
HFD2_k127_921870_2 Belongs to the helicase family. UvrD subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 529.0
HFD2_k127_921870_3 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 474.0
HFD2_k127_921870_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 468.0
HFD2_k127_921870_5 pyrroloquinoline quinone binding K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 409.0
HFD2_k127_921870_6 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 370.0
HFD2_k127_921870_7 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 308.0
HFD2_k127_921870_8 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 312.0
HFD2_k127_921870_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 281.0
HFD2_k127_945906_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1260.0
HFD2_k127_945906_1 Participates in both transcription termination and antitermination K02600 - - 4.661e-221 697.0
HFD2_k127_945906_10 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000000003554 196.0
HFD2_k127_945906_11 mttA/Hcf106 family K03116 - - 0.0000000000000000000000000000000000000000001131 165.0
HFD2_k127_945906_12 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000002841 149.0
HFD2_k127_945906_13 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000005101 145.0
HFD2_k127_945906_14 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000000000000000000002862 139.0
HFD2_k127_945906_15 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000006963 139.0
HFD2_k127_945906_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 8.415e-199 633.0
HFD2_k127_945906_3 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 580.0
HFD2_k127_945906_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 439.0
HFD2_k127_945906_6 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000005045 271.0
HFD2_k127_945906_7 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000004919 266.0
HFD2_k127_945906_8 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000006315 222.0
HFD2_k127_945906_9 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000000000000001301 203.0
HFD2_k127_948322_0 Beta-Casp domain K07576 - - 4.692e-229 721.0
HFD2_k127_948322_1 TIGRFAM type VI secretion system Vgr family protein K11904 - - 6.675e-195 653.0
HFD2_k127_948322_2 Uncharacterized protein conserved in bacteria (DUF2264) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 562.0
HFD2_k127_948322_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 462.0
HFD2_k127_948322_4 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 346.0
HFD2_k127_948322_5 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 291.0
HFD2_k127_948322_6 PFAM von Willebrand factor type A K07114,K12511 - - 0.0000000000003044 79.0
HFD2_k127_948986_0 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 2.101e-202 640.0
HFD2_k127_948986_1 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 518.0
HFD2_k127_948986_2 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008315 392.0
HFD2_k127_948986_3 domain protein K14194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002321 298.0
HFD2_k127_948986_4 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007532 278.0
HFD2_k127_948986_5 Mov34 MPN PAD-1 - - - 0.0000000000000000000000000000000000000000000000000000000000001836 223.0
HFD2_k127_948986_6 AI-2E family transporter - - - 0.00000001652 56.0
HFD2_k127_951951_0 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 612.0
HFD2_k127_951951_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 561.0
HFD2_k127_951951_10 COG0657 Esterase lipase - - - 0.0000000000000000000000000000000000000000000000000000002677 216.0
HFD2_k127_951951_11 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000009442 144.0
HFD2_k127_951951_12 cell redox homeostasis K03671 - - 0.00000000000000000000001184 102.0
HFD2_k127_951951_2 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 513.0
HFD2_k127_951951_3 peptidase S1 and S6, chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 494.0
HFD2_k127_951951_4 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 441.0
HFD2_k127_951951_5 GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 396.0
HFD2_k127_951951_6 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 330.0
HFD2_k127_951951_7 translation initiation inhibitor, yjgF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005033 280.0
HFD2_k127_951951_8 PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007241 273.0
HFD2_k127_951951_9 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000000000000000001401 226.0
HFD2_k127_952579_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1349.0
HFD2_k127_952579_1 COG3119 Arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008746 516.0
HFD2_k127_952579_2 AcrB/AcrD/AcrF family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 496.0
HFD2_k127_952579_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 362.0
HFD2_k127_952579_4 transcriptional regulator K09017 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000265 246.0
HFD2_k127_952579_5 transport - - - 0.00000000000000000000000000000000000000000000000000000000000000008657 226.0
HFD2_k127_963523_0 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 414.0
HFD2_k127_963523_1 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 300.0
HFD2_k127_963523_2 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000001028 228.0
HFD2_k127_963523_3 Belongs to the DapA family - - - 0.00000000000000000000000000000000000000000000000000000000000004189 217.0
HFD2_k127_964190_0 helicase activity - - - 2.073e-319 996.0
HFD2_k127_964190_1 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 552.0
HFD2_k127_964190_10 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000001334 237.0
HFD2_k127_964190_11 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000003992 162.0
HFD2_k127_964190_12 PFAM peptidase M55 D-aminopeptidase K16203 - - 0.0000000000000000000787 103.0
HFD2_k127_964190_13 TonB-dependent receptor - - - 0.00000457 57.0
HFD2_k127_964190_2 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 479.0
HFD2_k127_964190_3 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 436.0
HFD2_k127_964190_4 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 428.0
HFD2_k127_964190_5 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 354.0
HFD2_k127_964190_6 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 339.0
HFD2_k127_964190_7 carboxylic acid catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008851 331.0
HFD2_k127_964190_8 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 322.0
HFD2_k127_964190_9 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001435 293.0
HFD2_k127_968_0 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0 1820.0
HFD2_k127_968_1 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009385 257.0
HFD2_k127_968_2 FtsX-like permease family - - - 0.000000000000002676 83.0
HFD2_k127_985230_0 succinate dehydrogenase - - - 3.52e-250 788.0
HFD2_k127_985230_1 PFAM type II secretion system protein E K02283 - - 2.553e-238 753.0
HFD2_k127_985230_10 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 353.0
HFD2_k127_985230_11 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006922 323.0
HFD2_k127_985230_12 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 311.0
HFD2_k127_985230_13 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001591 280.0
HFD2_k127_985230_14 DinB family - - - 0.000000000000000000000000000000000000000000000003906 195.0
HFD2_k127_985230_15 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000004912 144.0
HFD2_k127_985230_2 peptidase dimerisation domain - - - 4.747e-236 736.0
HFD2_k127_985230_3 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 546.0
HFD2_k127_985230_4 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008995 482.0
HFD2_k127_985230_5 Psort location Cytoplasmic, score K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 428.0
HFD2_k127_985230_6 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008178 413.0
HFD2_k127_985230_7 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 404.0
HFD2_k127_985230_8 ADP-glyceromanno-heptose 6-epimerase activity K01710,K01784,K13318,K13322,K16439,K19857 - 4.2.1.46,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 371.0
HFD2_k127_985230_9 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006954 354.0
HFD2_k127_990731_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 409.0
HFD2_k127_990731_1 DREV methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 334.0
HFD2_k127_990731_3 Putative peptidoglycan binding domain - - - 0.0000000000000000000000000000000000000000000004488 177.0
HFD2_k127_990731_4 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000000000000003202 168.0
HFD2_k127_990731_5 alginic acid biosynthetic process K21449 - - 0.00000000000000000000001312 115.0
HFD2_k127_990731_7 DcrB - - - 0.0004414 48.0
HFD2_k127_994023_0 Belongs to the DapA family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000001034 186.0