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Overview

ID MAG01633
Name HFD2_bin.2
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Polarisedimenticolia
Order Gp22-AA2
Family Gp22-AA2
Genus DASRJX01
Species
Assembly information
Completeness (%) 79.48
Contamination (%) 2.77
GC content (%) 70.0
N50 (bp) 9,639
Genome size (bp) 3,195,838

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2725

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_1007107_0 C-terminus of AA_permease K03294 - - 3.675e-244 763.0
HFD2_k127_1007107_1 glutamate decarboxylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 393.0
HFD2_k127_1007107_2 Aminotransferase K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008709 412.0
HFD2_k127_1007107_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000003749 201.0
HFD2_k127_1007107_4 - - - - 0.0000000000000000000000005867 121.0
HFD2_k127_1007107_5 long-chain fatty acid transport protein - - - 0.0000000000000000000001199 105.0
HFD2_k127_1007342_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0 1393.0
HFD2_k127_1007342_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 381.0
HFD2_k127_1007342_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 291.0
HFD2_k127_1007342_3 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000000000000000000000005396 214.0
HFD2_k127_1007342_4 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000626 179.0
HFD2_k127_1007342_5 Outer membrane efflux protein - - - 0.00000000000000000000000000000002233 143.0
HFD2_k127_1007342_6 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000003256 57.0
HFD2_k127_1007342_7 Transcriptional regulator, DeoR family K21601 - - 0.0000003054 63.0
HFD2_k127_1007342_8 - - - - 0.0000005659 60.0
HFD2_k127_1014454_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 621.0
HFD2_k127_1014454_1 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000007908 156.0
HFD2_k127_1014454_2 Belongs to the peptidase M48B family - - - 0.000000000000000000000004985 116.0
HFD2_k127_1014454_3 TIGRFAM TonB-dependent heme hemoglobin receptor family protein K02014,K16087 - - 0.0000000000000001093 94.0
HFD2_k127_1014454_4 Penicillinase repressor - - - 0.0000000000000003958 86.0
HFD2_k127_1014454_5 PFAM Rh family protein ammonium transporter K03320 - - 0.0000000000000005045 78.0
HFD2_k127_1020067_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 377.0
HFD2_k127_1020356_0 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004938 245.0
HFD2_k127_1020356_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000001343 172.0
HFD2_k127_1020356_2 Alginate export - - - 0.000000000000000000000000004502 121.0
HFD2_k127_1020356_3 - - - - 0.0000000000000000000029 99.0
HFD2_k127_1043512_0 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 532.0
HFD2_k127_1043512_1 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 447.0
HFD2_k127_1043512_2 Ribonuclease E/G family K08300,K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 415.0
HFD2_k127_1043512_3 Cell cycle protein K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 300.0
HFD2_k127_1043512_4 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000038 211.0
HFD2_k127_1043512_5 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000007244 162.0
HFD2_k127_1043512_6 PFAM FecR protein - - - 0.00000000000000002132 93.0
HFD2_k127_1043512_7 rod shape-determining protein MreD K03571 - - 0.0005378 48.0
HFD2_k127_1047087_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 557.0
HFD2_k127_1047087_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 437.0
HFD2_k127_1047087_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 355.0
HFD2_k127_1055031_0 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000001496 244.0
HFD2_k127_1055031_1 Sulfurtransferase TusA - - - 0.00000000000001533 76.0
HFD2_k127_1064103_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 5.402e-267 843.0
HFD2_k127_1064103_1 Peptidase family M1 domain - - - 7.123e-258 807.0
HFD2_k127_1064103_10 Carboxylesterase K06999 - - 0.0000000000000000000000000000000000000000000000000000000003632 211.0
HFD2_k127_1064103_11 Sodium:solute symporter family K03307 - - 0.00000000000000000000000000000000000000000000000000000009387 213.0
HFD2_k127_1064103_12 deoxyhypusine monooxygenase activity K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000002531 183.0
HFD2_k127_1064103_13 Thrombospondin type 3 repeat - - - 0.0000000000000000000000000000000000000000000002266 193.0
HFD2_k127_1064103_14 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000001155 134.0
HFD2_k127_1064103_15 endoribonuclease L-PSP - - - 0.0000000000000000000000001405 125.0
HFD2_k127_1064103_16 OmpA-like transmembrane domain - - - 0.0000000000000000004159 104.0
HFD2_k127_1064103_2 COG0493 NADPH-dependent glutamate synthase beta chain and K00266 - 1.4.1.13,1.4.1.14 1.419e-243 777.0
HFD2_k127_1064103_3 Involved in the tonB-independent uptake of proteins K03641 - - 1.506e-203 661.0
HFD2_k127_1064103_4 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 541.0
HFD2_k127_1064103_5 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009568 532.0
HFD2_k127_1064103_6 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 407.0
HFD2_k127_1064103_7 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 366.0
HFD2_k127_1064103_8 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 318.0
HFD2_k127_1064103_9 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005932 276.0
HFD2_k127_1071260_0 Ribonuclease E/G family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 460.0
HFD2_k127_1071260_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008219 310.0
HFD2_k127_1071260_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 296.0
HFD2_k127_1071260_3 N,N-dimethylaniline monooxygenase activity - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001997 272.0
HFD2_k127_1071260_4 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000171 262.0
HFD2_k127_1071260_5 amidohydrolase - - - 0.000000000000000003565 94.0
HFD2_k127_1071260_7 polymorphic outer membrane protein - - - 0.000000000002516 79.0
HFD2_k127_1071260_8 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.000004692 60.0
HFD2_k127_1100726_0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009695 577.0
HFD2_k127_1100726_1 plastoquinone (Complex I) K12141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 544.0
HFD2_k127_1100726_10 hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000000000005183 212.0
HFD2_k127_1100726_11 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000005876 180.0
HFD2_k127_1100726_12 Zn_pept - - - 0.000000000000000000000000002507 126.0
HFD2_k127_1100726_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 494.0
HFD2_k127_1100726_3 Proton-conducting membrane transporter K12137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 497.0
HFD2_k127_1100726_4 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006216 421.0
HFD2_k127_1100726_5 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 344.0
HFD2_k127_1100726_6 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007344 334.0
HFD2_k127_1100726_7 RNA pseudouridylate synthase K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 328.0
HFD2_k127_1100726_8 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 318.0
HFD2_k127_1100726_9 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000008324 226.0
HFD2_k127_1102004_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 584.0
HFD2_k127_1102004_1 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 387.0
HFD2_k127_1102004_10 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000006122 93.0
HFD2_k127_1102004_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 371.0
HFD2_k127_1102004_3 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000009189 281.0
HFD2_k127_1102004_4 (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003009 267.0
HFD2_k127_1102004_5 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000002336 218.0
HFD2_k127_1102004_6 - - - - 0.000000000000000000000000000000000000000000000000001227 195.0
HFD2_k127_1102004_7 Flavoprotein K03186 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 0.00000000000000000000000000000000000000001683 166.0
HFD2_k127_1102004_8 - - - - 0.0000000000000000000000000000003572 130.0
HFD2_k127_1102004_9 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000005428 123.0
HFD2_k127_1102236_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 422.0
HFD2_k127_1102236_1 Uncharacterized ACR, COG1993 K06199,K09137 - - 0.000000000000000000000000000000000000000007326 155.0
HFD2_k127_1102236_2 cell redox homeostasis K03671 - - 0.000000000000000000005246 106.0
HFD2_k127_1102236_3 Thioredoxin - - - 0.00000000000002281 87.0
HFD2_k127_1102236_4 - - - - 0.0000004135 56.0
HFD2_k127_1111460_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.068e-298 929.0
HFD2_k127_1111460_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009944 320.0
HFD2_k127_1111460_2 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 302.0
HFD2_k127_1111460_3 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.0000000000000000000000000000000003101 140.0
HFD2_k127_1111460_4 Ferredoxin - - - 0.000000000000000000000001354 108.0
HFD2_k127_1111460_5 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000002501 115.0
HFD2_k127_1111460_6 - - - - 0.00003529 57.0
HFD2_k127_11695_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 550.0
HFD2_k127_11695_1 Cys/Met metabolism PLP-dependent enzyme K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 470.0
HFD2_k127_11695_10 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 306.0
HFD2_k127_11695_11 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003045 286.0
HFD2_k127_11695_12 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007814 279.0
HFD2_k127_11695_13 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000003776 260.0
HFD2_k127_11695_14 TIGRFAM MazG family protein K02428,K02499 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000009099 264.0
HFD2_k127_11695_15 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000006356 260.0
HFD2_k127_11695_16 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000494 243.0
HFD2_k127_11695_17 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000001716 220.0
HFD2_k127_11695_18 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000758 215.0
HFD2_k127_11695_19 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000004645 207.0
HFD2_k127_11695_2 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 430.0
HFD2_k127_11695_20 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000488 164.0
HFD2_k127_11695_21 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000003237 168.0
HFD2_k127_11695_22 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000003003 137.0
HFD2_k127_11695_23 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000002271 111.0
HFD2_k127_11695_24 Uncharacterized ACR, COG1399 K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000002432 115.0
HFD2_k127_11695_25 Regulatory protein - - - 0.00000000000000000000001979 105.0
HFD2_k127_11695_26 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000303 96.0
HFD2_k127_11695_27 Tetratricopeptide repeat - - - 0.0000000000000000000009507 111.0
HFD2_k127_11695_28 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000001218 92.0
HFD2_k127_11695_29 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000116 69.0
HFD2_k127_11695_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 393.0
HFD2_k127_11695_30 DnaJ molecular chaperone homology domain - - - 0.000001056 61.0
HFD2_k127_11695_31 Tetratricopeptide repeat - - - 0.00004651 54.0
HFD2_k127_11695_33 Domain of unknown function (DUF1844) - - - 0.00006615 51.0
HFD2_k127_11695_34 Belongs to the 'phage' integrase family - - - 0.0003634 47.0
HFD2_k127_11695_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 391.0
HFD2_k127_11695_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 369.0
HFD2_k127_11695_6 Belongs to the 'phage' integrase family K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 308.0
HFD2_k127_11695_7 Zinc-binding dehydrogenase K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 313.0
HFD2_k127_11695_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 314.0
HFD2_k127_11695_9 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 291.0
HFD2_k127_1194223_0 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007951 399.0
HFD2_k127_1194223_1 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000003074 246.0
HFD2_k127_1194223_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000005287 233.0
HFD2_k127_1194223_3 Staphylococcal nuclease homologues K01174,K01286 - 3.1.31.1,3.4.16.4 0.0000000000000000000000000000003296 131.0
HFD2_k127_1195931_0 AcrB/AcrD/AcrF family - - - 0.0 1139.0
HFD2_k127_1195931_1 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005065 441.0
HFD2_k127_1195931_10 Calcium/calmodulin dependent protein kinase II association domain - - - 0.0000005488 59.0
HFD2_k127_1195931_2 Aldehyde dehydrogenase family K00130 - 1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 284.0
HFD2_k127_1195931_3 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001027 269.0
HFD2_k127_1195931_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000002029 201.0
HFD2_k127_1195931_5 SWI complex, BAF60b domains - - - 0.0000000000000000000000000000002126 129.0
HFD2_k127_1195931_6 Yip1 domain - - - 0.00000000000000000000000000009331 127.0
HFD2_k127_1195931_7 Outer membrane efflux protein - - - 0.000000000000000000000000003545 127.0
HFD2_k127_1195931_8 Tetratricopeptide repeat - - - 0.000000000000000003151 100.0
HFD2_k127_1195931_9 Protein of unknown function (DUF2892) - - - 0.00000000000000005506 85.0
HFD2_k127_1203946_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 530.0
HFD2_k127_1203946_1 Peptidase S15 K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 463.0
HFD2_k127_1203946_2 COG1078 HD superfamily phosphohydrolases K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003194 289.0
HFD2_k127_1203946_3 GAF domain-containing protein K08968 - 1.8.4.14 0.000000000000000000000000000000000000000000000000000000000000001383 224.0
HFD2_k127_1203946_4 Ankyrin repeat - - - 0.000000000000000000000000000000000000001287 154.0
HFD2_k127_1203946_5 Lysin motif - - - 0.00000000000000000000000000000000000006506 159.0
HFD2_k127_1206603_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 423.0
HFD2_k127_1206603_1 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003193 261.0
HFD2_k127_1206603_2 Family of unknown function (DUF695) - - - 0.00000000001249 74.0
HFD2_k127_1206603_3 YwiC-like protein - - - 0.00000007006 64.0
HFD2_k127_120921_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 456.0
HFD2_k127_120921_1 Protein of unknown function (DUF502) - - - 0.0000000000000002978 81.0
HFD2_k127_123469_0 Cys/Met metabolism PLP-dependent enzyme K01739,K01761 - 2.5.1.48,4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 521.0
HFD2_k127_123469_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 473.0
HFD2_k127_123469_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000003394 165.0
HFD2_k127_123469_3 MacB-like periplasmic core domain - - - 0.0000004463 52.0
HFD2_k127_1273614_0 MatE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005314 457.0
HFD2_k127_1273614_1 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 380.0
HFD2_k127_1273614_2 Rieske 2Fe-2S domain protein K00479 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 318.0
HFD2_k127_1273614_3 B12 binding domain - - - 0.0000000000000000000000000000000000000000008077 177.0
HFD2_k127_1273614_4 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000000000000000008448 160.0
HFD2_k127_1275793_0 Bacterial regulatory protein, Fis family K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008814 333.0
HFD2_k127_1275793_1 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001714 285.0
HFD2_k127_1275793_2 Peptidase M56 - - - 0.00008123 52.0
HFD2_k127_1275793_3 Peptidase S24-like K13280 - 3.4.21.89 0.0001479 54.0
HFD2_k127_1282339_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 494.0
HFD2_k127_1282339_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007183 435.0
HFD2_k127_1282339_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 423.0
HFD2_k127_1282339_3 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000006918 256.0
HFD2_k127_1282339_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000001182 193.0
HFD2_k127_1282339_5 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000001069 153.0
HFD2_k127_1282339_6 PAP2 superfamily - - - 0.000000003581 67.0
HFD2_k127_1331088_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008705 344.0
HFD2_k127_1331088_1 COG2031 Short chain fatty acids transporter K02106 - - 0.00000000000000000000000002959 116.0
HFD2_k127_1359328_0 Linear gramicidin synthase subunit - - - 0.0 1102.0
HFD2_k127_1359328_1 polyketide synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 600.0
HFD2_k127_141425_0 Prokaryotic cytochrome b561 - - - 3.713e-249 788.0
HFD2_k127_141425_1 lysine 2,3-aminomutase K01843 - 5.4.3.2 1.149e-243 759.0
HFD2_k127_141425_10 Surface antigen K07277,K09800 - - 0.0000000000000000000000000000000000000000000000000000008808 222.0
HFD2_k127_141425_11 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000004241 206.0
HFD2_k127_141425_12 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.0000000000000000000000000000000000000000000001397 185.0
HFD2_k127_141425_13 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) - - - 0.000000000000000000000000000000000000000000001198 169.0
HFD2_k127_141425_14 amine dehydrogenase activity K21449 - - 0.0000000000000000000000000000000000000002195 157.0
HFD2_k127_141425_15 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000002718 146.0
HFD2_k127_141425_16 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.0000000000000000000000000000001883 137.0
HFD2_k127_141425_17 PDZ domain (Also known as DHR or GLGF) K03797 - 3.4.21.102 0.000000000000000000004098 110.0
HFD2_k127_141425_18 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.000000000000000000539 94.0
HFD2_k127_141425_19 Heme copper-type cytochrome quinol oxidases, subunit 2 K02275,K02826,K15864 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.10.3.12,1.7.2.1,1.7.99.1,1.9.3.1 0.000002522 55.0
HFD2_k127_141425_2 formate dehydrogenase - - - 2.562e-233 766.0
HFD2_k127_141425_20 PFAM IstB domain protein ATP-binding protein - - - 0.0002925 52.0
HFD2_k127_141425_3 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005876 434.0
HFD2_k127_141425_4 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 353.0
HFD2_k127_141425_5 calcium, potassium:sodium antiporter activity K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 347.0
HFD2_k127_141425_6 Cytochrome c554 and c-prime K03620 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 346.0
HFD2_k127_141425_7 histidine kinase A domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 310.0
HFD2_k127_141425_8 Domain of unknown function (DUF4162) K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006582 271.0
HFD2_k127_141425_9 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000008635 229.0
HFD2_k127_142227_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.941e-271 846.0
HFD2_k127_142227_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007118 402.0
HFD2_k127_142227_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005969 315.0
HFD2_k127_142227_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000001537 200.0
HFD2_k127_142227_4 Subtilase family - - - 0.0000000000000000000000000001059 136.0
HFD2_k127_1426466_0 electron transfer activity K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 601.0
HFD2_k127_1426466_1 DEAD DEAH box helicase K03724 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 552.0
HFD2_k127_1434516_0 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000001465 254.0
HFD2_k127_1434516_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000002026 151.0
HFD2_k127_1434516_2 Belongs to the glycosyl hydrolase 18 family - - - 0.00001398 59.0
HFD2_k127_1482336_0 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 413.0
HFD2_k127_1482336_1 Peptidase family M23 K01406 - 3.4.24.40 0.00000000000000000000000000000000000000000000000000000000000001089 243.0
HFD2_k127_1482336_2 histone H2A K63-linked ubiquitination K10914 - - 0.0000000000000000000000000000000000000001037 161.0
HFD2_k127_1482336_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000002741 140.0
HFD2_k127_1482336_4 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 0.00000000000000000000002062 108.0
HFD2_k127_153290_0 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001329 287.0
HFD2_k127_153290_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009485 271.0
HFD2_k127_153290_2 peroxiredoxin activity K03386,K03564,K16922 - 1.11.1.15 0.00000000000000000000000000003991 123.0
HFD2_k127_1585438_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 5.686e-225 709.0
HFD2_k127_1585438_1 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000694 273.0
HFD2_k127_1640173_0 SIS domain - - - 0.000000000000000000000000000000000000000000000000001186 190.0
HFD2_k127_1640173_1 Uncharacterised nucleotidyltransferase - - - 0.00000000000001791 86.0
HFD2_k127_1656524_0 PFAM Cytochrome b b6 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 418.0
HFD2_k127_1656524_1 Cytochrome b(C-terminal)/b6/petD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006288 384.0
HFD2_k127_1656524_2 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 332.0
HFD2_k127_1656524_3 Pfam Glycosyl transferase family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 310.0
HFD2_k127_1656524_4 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000000001409 215.0
HFD2_k127_1656524_5 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000726 170.0
HFD2_k127_1656524_6 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.00000000000000000000000006811 115.0
HFD2_k127_1656524_7 PBS lyase HEAT-like repeat - - - 0.000001616 61.0
HFD2_k127_1656524_8 Cytochrome C oxidase, mono-heme subunit/FixO K00405,K01153,K09760,K12132 - 2.7.11.1,3.1.21.3 0.00002302 54.0
HFD2_k127_1669188_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 439.0
HFD2_k127_1669188_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 300.0
HFD2_k127_1669188_2 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000006386 235.0
HFD2_k127_1669188_3 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000346 211.0
HFD2_k127_1669188_4 FR47-like protein - - - 0.0000000000000000000000000000000002828 145.0
HFD2_k127_1669188_5 peroxiredoxin activity - - - 0.00000000000000000000000000000001057 134.0
HFD2_k127_1669188_6 - - - - 0.0000000000000000000000000000007457 129.0
HFD2_k127_1669188_7 Domain of unknown function (DUF1330) - - - 0.000000000000000000000001748 113.0
HFD2_k127_1682923_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1353.0
HFD2_k127_1682923_1 Flavin containing amine oxidoreductase - - - 3.658e-271 846.0
HFD2_k127_1682923_10 HlyD family secretion protein K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 353.0
HFD2_k127_1682923_11 - - - - 0.0000007668 63.0
HFD2_k127_1682923_12 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. - - - 0.00002514 51.0
HFD2_k127_1682923_2 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007221 581.0
HFD2_k127_1682923_3 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 505.0
HFD2_k127_1682923_4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004603 459.0
HFD2_k127_1682923_5 Glycosyl hydrolase family 57 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 440.0
HFD2_k127_1682923_6 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 436.0
HFD2_k127_1682923_7 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 381.0
HFD2_k127_1682923_8 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 378.0
HFD2_k127_1682923_9 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 393.0
HFD2_k127_1710374_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 441.0
HFD2_k127_1710374_1 carbamoylphosphate synthase K01948,K11541 GO:0000050,GO:0000052,GO:0000096,GO:0000166,GO:0001101,GO:0001505,GO:0001889,GO:0002237,GO:0003008,GO:0003013,GO:0003018,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0004175,GO:0005488,GO:0005509,GO:0005524,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006082,GO:0006508,GO:0006520,GO:0006525,GO:0006526,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007275,GO:0007494,GO:0008015,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008289,GO:0008652,GO:0009056,GO:0009058,GO:0009064,GO:0009084,GO:0009295,GO:0009410,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009719,GO:0009725,GO:0009888,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010038,GO:0010043,GO:0010243,GO:0014070,GO:0014074,GO:0014075,GO:0016020,GO:0016042,GO:0016053,GO:0016595,GO:0016597,GO:0016787,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0017144,GO:0019240,GO:0019433,GO:0019538,GO:0019627,GO:0019637,GO:0019752,GO:0019866,GO:0030154,GO:0030554,GO:0030855,GO:0031090,GO:0031406,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032094,GO:0032496,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032870,GO:0032991,GO:0033762,GO:0033993,GO:0034201,GO:0034641,GO:0035150,GO:0035295,GO:0035296,GO:0035639,GO:0036094,GO:0042133,GO:0042221,GO:0042311,GO:0042493,GO:0042592,GO:0042594,GO:0042645,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043200,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043434,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044283,GO:0044344,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0046209,GO:0046394,GO:0046461,GO:0046464,GO:0046486,GO:0046503,GO:0046683,GO:0046872,GO:0048513,GO:0048545,GO:0048565,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0048878,GO:0050667,GO:0050801,GO:0050880,GO:0050896,GO:0051384,GO:0051591,GO:0051704,GO:0051707,GO:0051716,GO:0055081,GO:0055123,GO:0060416,GO:0060429,GO:0061008,GO:0065007,GO:0065008,GO:0070011,GO:0070013,GO:0070365,GO:0070408,GO:0070409,GO:0070542,GO:0070848,GO:0070887,GO:0071229,GO:0071310,GO:0071320,GO:0071363,GO:0071375,GO:0071377,GO:0071396,GO:0071398,GO:0071400,GO:0071407,GO:0071417,GO:0071495,GO:0071548,GO:0071704,GO:0071774,GO:0071941,GO:0072341,GO:0072593,GO:0090066,GO:0090407,GO:0097159,GO:0097237,GO:0097327,GO:0097367,GO:0097746,GO:0097755,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607,GO:1901652,GO:1901653,GO:1901654,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1903717,GO:1903718,GO:2001057 2.1.3.2,6.3.4.16,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 413.0
HFD2_k127_1710374_10 TPR repeat Sel1-like repeat Tetratricopeptide TPR_3 Tetratricopeptide TPR_2 - - - 0.00004757 55.0
HFD2_k127_1710374_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 336.0
HFD2_k127_1710374_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K04068,K10026 - 1.97.1.4,4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001158 278.0
HFD2_k127_1710374_4 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000003682 269.0
HFD2_k127_1710374_5 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000138 258.0
HFD2_k127_1710374_6 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000001735 237.0
HFD2_k127_1710374_7 Aminotransferase K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000184 235.0
HFD2_k127_1710374_8 Carbamoyl-phosphate synthase (glutamine-hydrolyzing) K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000007956 201.0
HFD2_k127_1710374_9 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.00000000000000000000000000000000000000008472 171.0
HFD2_k127_1761557_0 elongation factor Tu domain 2 protein K02355 - - 3.855e-234 744.0
HFD2_k127_1761557_1 Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 557.0
HFD2_k127_1761557_10 Acid phosphatase homologues - - - 0.0000000000000000000005522 104.0
HFD2_k127_1761557_2 ABC transporter transmembrane region K06147,K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 554.0
HFD2_k127_1761557_3 ABC transporter, transmembrane K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 424.0
HFD2_k127_1761557_4 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 415.0
HFD2_k127_1761557_5 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000004262 266.0
HFD2_k127_1761557_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000000006911 213.0
HFD2_k127_1761557_7 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000007597 180.0
HFD2_k127_1761557_8 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000114 132.0
HFD2_k127_1761557_9 enzyme binding K00567,K07443 - 2.1.1.63 0.0000000000000000000001613 101.0
HFD2_k127_1764795_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.326e-221 699.0
HFD2_k127_1764795_1 PFAM DAHP synthetase I K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 354.0
HFD2_k127_1764795_10 - - - - 0.0001549 52.0
HFD2_k127_1764795_2 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 352.0
HFD2_k127_1764795_3 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003296 276.0
HFD2_k127_1764795_4 COG0859 ADP-heptose LPS heptosyltransferase K02841,K02849 - - 0.0000000000000000000000000000000000000000000000002503 189.0
HFD2_k127_1764795_5 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K01627,K03270 - 2.5.1.55,3.1.3.45 0.0000000000000000000000000000000000000000003018 165.0
HFD2_k127_1764795_6 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000003004 148.0
HFD2_k127_1764795_7 Domain of unknown function (DUF4388) - - - 0.000000000000000000000001667 112.0
HFD2_k127_1764795_8 Trm112p-like protein K00912,K09791 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.1.130 0.00000000000000001801 83.0
HFD2_k127_1764795_9 transcriptional regulator, SARP family - - - 0.00000121 61.0
HFD2_k127_1778144_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.07e-303 953.0
HFD2_k127_1778144_1 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 361.0
HFD2_k127_1778144_2 CoA binding domain K06929 - - 0.00000000000000000000000000000000000312 142.0
HFD2_k127_1778144_3 - - - - 0.0000000000000000000000000000000004104 142.0
HFD2_k127_1778144_4 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000162 139.0
HFD2_k127_1787983_0 Amylo-alpha-1,6-glucosidase - - - 1.539e-245 777.0
HFD2_k127_1787983_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000000000002247 203.0
HFD2_k127_1794698_0 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000007005 240.0
HFD2_k127_1794698_1 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000000002726 173.0
HFD2_k127_1794698_2 Universal stress protein K06149 - - 0.0000000000006089 78.0
HFD2_k127_1794698_3 CBS domain K04767 - - 0.000000000001275 81.0
HFD2_k127_1798786_0 serine-type peptidase activity K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 623.0
HFD2_k127_1798786_1 Short chain fatty acid transporter K02106 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008815 442.0
HFD2_k127_1798786_2 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001068 281.0
HFD2_k127_1798786_3 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.00000000000000000000000000000000000000000000005426 194.0
HFD2_k127_1798786_4 Smr domain - - - 0.000000000000000000000000000002156 123.0
HFD2_k127_1798786_5 Protein of unknown function (DUF2905) - - - 0.0000000000000001886 82.0
HFD2_k127_1798786_6 Subtilase family - - - 0.0000000000000005449 93.0
HFD2_k127_1800280_0 Ferritin-like domain - - - 0.0000000000000000000000000000000000000000000000000000003961 195.0
HFD2_k127_1800280_1 Phosphate-selective porin O and P - - - 0.0000000000000000000000000000001316 139.0
HFD2_k127_1809531_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 414.0
HFD2_k127_1809531_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000002757 173.0
HFD2_k127_1809531_2 HYR domain - - - 0.000000000000000002379 98.0
HFD2_k127_1819905_0 FAD binding domain K00103,K00279 - 1.1.3.8,1.5.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 323.0
HFD2_k127_1819905_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007631 285.0
HFD2_k127_1819905_10 - - - - 0.0000003124 58.0
HFD2_k127_1819905_11 Condensation domain - - - 0.000005064 59.0
HFD2_k127_1819905_12 - - - - 0.0003445 51.0
HFD2_k127_1819905_2 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005217 262.0
HFD2_k127_1819905_3 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000004439 162.0
HFD2_k127_1819905_4 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000001353 154.0
HFD2_k127_1819905_5 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000000038 129.0
HFD2_k127_1819905_6 Uncharacterized ACR, COG1993 K06199,K09137 - - 0.0000000000000000000004941 98.0
HFD2_k127_1819905_7 tetratricopeptide - - - 0.0000000000000000000005852 111.0
HFD2_k127_1819905_8 - - - - 0.000000000000000000003389 103.0
HFD2_k127_1819905_9 - - - - 0.000000000000000000005085 96.0
HFD2_k127_1828803_0 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000001253 175.0
HFD2_k127_1828803_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000002883 162.0
HFD2_k127_1828803_2 Protein kinase domain K12132 - 2.7.11.1 0.0000001273 55.0
HFD2_k127_1828803_3 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00003224 57.0
HFD2_k127_1847963_0 SNF2 Helicase protein - - - 0.0 1290.0
HFD2_k127_1847963_1 radical SAM domain protein - - - 1.47e-224 707.0
HFD2_k127_1847963_2 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 433.0
HFD2_k127_1847963_3 SWIM zinc finger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 331.0
HFD2_k127_1847963_4 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001326 286.0
HFD2_k127_1847963_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000181 253.0
HFD2_k127_1847963_6 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002083 252.0
HFD2_k127_1847963_7 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.000000000000000000000000000000000003207 141.0
HFD2_k127_1847963_8 Dehydrogenase - - - 0.000007088 59.0
HFD2_k127_1857495_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 528.0
HFD2_k127_1857495_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 372.0
HFD2_k127_1857495_2 Alpha beta K22318 - - 0.000000000000003089 84.0
HFD2_k127_1862545_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0033554,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 344.0
HFD2_k127_1862545_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000001577 245.0
HFD2_k127_1862545_2 Heme copper-type cytochrome quinol oxidase, subunit K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000266 177.0
HFD2_k127_1862545_3 Beta-lactamase K17836 - 3.5.2.6 0.000000000000000000000000000000000000000002538 170.0
HFD2_k127_1862545_4 Protein of unknown function (DUF420) K08976 - - 0.000000000000000000000000000000000000008512 149.0
HFD2_k127_1862545_5 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000003218 145.0
HFD2_k127_1862545_6 cytochrome oxidase assembly K02259 - - 0.00000000000000006566 88.0
HFD2_k127_1862545_7 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000007898 56.0
HFD2_k127_186940_0 Prolyl oligopeptidase family - - - 3.093e-247 781.0
HFD2_k127_186940_1 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 481.0
HFD2_k127_186940_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000009184 245.0
HFD2_k127_186940_3 Pterin 4 alpha carbinolamine dehydratase K01724,K11991 - 3.5.4.33,4.2.1.96 0.000000000000000000000000000000000000000000000000004911 192.0
HFD2_k127_186940_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000001248 173.0
HFD2_k127_186940_5 Formaldehyde-activating enzyme (Fae) - - - 0.00000000000000000000000000000000000002079 151.0
HFD2_k127_186940_6 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000002472 123.0
HFD2_k127_186940_7 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000001376 118.0
HFD2_k127_186940_9 Heat shock 70 kDa protein - - - 0.00001745 55.0
HFD2_k127_1893267_0 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001129 250.0
HFD2_k127_1893267_1 - - - - 0.0000000000000000000000001517 118.0
HFD2_k127_1893267_3 signal peptide processing K13280 - 3.4.21.89 0.0008015 48.0
HFD2_k127_1897851_0 peptidase activity, acting on L-amino acid peptides K01337,K01400,K20276 - 3.4.21.50,3.4.24.28 0.0000000000000000000000000000000000000000002172 185.0
HFD2_k127_1897851_1 Belongs to the peptidase S8 family - - - 0.000000000000000000000000004947 131.0
HFD2_k127_1897851_2 Cartilage oligomeric matrix protein K04659 GO:0000902,GO:0001501,GO:0001503,GO:0001932,GO:0001934,GO:0001936,GO:0001938,GO:0001968,GO:0002020,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0002688,GO:0002690,GO:0003416,GO:0003417,GO:0003674,GO:0005102,GO:0005178,GO:0005198,GO:0005201,GO:0005488,GO:0005496,GO:0005499,GO:0005509,GO:0005515,GO:0005518,GO:0005539,GO:0005575,GO:0005576,GO:0005604,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005912,GO:0005924,GO:0005927,GO:0006928,GO:0006950,GO:0007155,GO:0007160,GO:0007275,GO:0007399,GO:0007517,GO:0007610,GO:0008150,GO:0008201,GO:0008284,GO:0008289,GO:0009653,GO:0009790,GO:0009887,GO:0009888,GO:0009893,GO:0009987,GO:0010562,GO:0010604,GO:0010941,GO:0012505,GO:0014812,GO:0016043,GO:0016203,GO:0016477,GO:0016525,GO:0016528,GO:0016529,GO:0019220,GO:0019222,GO:0019842,GO:0019899,GO:0021700,GO:0022008,GO:0022603,GO:0022607,GO:0022610,GO:0030030,GO:0030054,GO:0030055,GO:0030154,GO:0030182,GO:0030198,GO:0030334,GO:0030335,GO:0030855,GO:0031012,GO:0031175,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0031589,GO:0031594,GO:0032101,GO:0032103,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032879,GO:0032989,GO:0032990,GO:0032991,GO:0033554,GO:0033555,GO:0033627,GO:0034103,GO:0034976,GO:0035265,GO:0035989,GO:0036094,GO:0040007,GO:0040011,GO:0040012,GO:0040017,GO:0042127,GO:0042325,GO:0042327,GO:0042981,GO:0043062,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043236,GO:0043237,GO:0043394,GO:0043395,GO:0043931,GO:0043933,GO:0044085,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045202,GO:0045765,GO:0045937,GO:0046872,GO:0048265,GO:0048266,GO:0048468,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048589,GO:0048646,GO:0048666,GO:0048699,GO:0048705,GO:0048731,GO:0048736,GO:0048799,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050678,GO:0050679,GO:0050730,GO:0050731,GO:0050789,GO:0050793,GO:0050794,GO:0050839,GO:0050840,GO:0050896,GO:0050920,GO:0050921,GO:0051093,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051216,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0051270,GO:0051272,GO:0051451,GO:0051674,GO:0051716,GO:0060173,GO:0060231,GO:0060255,GO:0060343,GO:0060346,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060429,GO:0060538,GO:0060548,GO:0061053,GO:0061061,GO:0061383,GO:0061430,GO:0061448,GO:0062023,GO:0065003,GO:0065007,GO:0070161,GO:0070977,GO:0071603,GO:0071622,GO:0071624,GO:0071695,GO:0071840,GO:0080090,GO:0090022,GO:0090023,GO:0090136,GO:0097159,GO:0097367,GO:0098609,GO:0098868,GO:0120036,GO:0120039,GO:1901342,GO:1901343,GO:1901681,GO:1902622,GO:1902624,GO:2000026,GO:2000145,GO:2000147,GO:2000181 - 0.00000000000000000000000007723 127.0
HFD2_k127_1897851_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000007982 67.0
HFD2_k127_1898956_0 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 458.0
HFD2_k127_1898956_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000001452 207.0
HFD2_k127_1899903_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 3.667e-238 771.0
HFD2_k127_1899903_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 525.0
HFD2_k127_1899903_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008311 354.0
HFD2_k127_1899903_3 PFAM adenosine AMP deaminase K01488 - 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000005978 236.0
HFD2_k127_1899903_4 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 0.000000000000000000000000000000000000000000002593 168.0
HFD2_k127_1899903_5 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000001789 184.0
HFD2_k127_1899903_6 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000008995 155.0
HFD2_k127_1899903_7 Cytochrome c - - - 0.00003111 57.0
HFD2_k127_190107_0 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 477.0
HFD2_k127_190107_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 387.0
HFD2_k127_190107_10 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000006973 177.0
HFD2_k127_190107_11 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000002429 160.0
HFD2_k127_190107_12 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000001853 103.0
HFD2_k127_190107_13 - - - - 0.000000000000000007927 89.0
HFD2_k127_190107_14 Cyclophilin-like K09143 - - 0.000000000000118 84.0
HFD2_k127_190107_15 arsenate reductase (glutaredoxin) activity K00537 - 1.20.4.1 0.0000000006479 63.0
HFD2_k127_190107_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002473 295.0
HFD2_k127_190107_3 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001771 291.0
HFD2_k127_190107_4 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000001191 259.0
HFD2_k127_190107_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000203 258.0
HFD2_k127_190107_6 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000006986 239.0
HFD2_k127_190107_7 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000005904 217.0
HFD2_k127_190107_8 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000001134 210.0
HFD2_k127_190107_9 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000005995 188.0
HFD2_k127_1921728_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 331.0
HFD2_k127_1921728_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 332.0
HFD2_k127_1921728_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.000000000000000000000000000000003047 135.0
HFD2_k127_1921728_3 ATP synthase delta (OSCP) subunit K02113 - - 0.0000000000000000000006285 100.0
HFD2_k127_1921728_4 ATP synthase subunit C K02110 - - 0.0000000000000001001 82.0
HFD2_k127_1933225_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000002067 234.0
HFD2_k127_1933225_1 TonB C terminal - - - 0.00000000003201 75.0
HFD2_k127_1933225_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01179 - 3.2.1.4 0.000000002035 70.0
HFD2_k127_1933225_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000009008 53.0
HFD2_k127_1933225_4 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0004607 52.0
HFD2_k127_194835_0 ATP-dependent helicase K03579 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 583.0
HFD2_k127_194835_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 546.0
HFD2_k127_194835_10 Protein of unknown function (DUF2846) - - - 0.0000000001673 72.0
HFD2_k127_194835_11 - - - - 0.0001758 50.0
HFD2_k127_194835_2 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 482.0
HFD2_k127_194835_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 452.0
HFD2_k127_194835_4 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 437.0
HFD2_k127_194835_5 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 387.0
HFD2_k127_194835_6 Site-specific DNA-methyltransferase (Adenine-specific) K06223 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 364.0
HFD2_k127_194835_7 PFAM Alanine dehydrogenase PNT, C-terminal domain K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006237 369.0
HFD2_k127_194835_8 - K00003,K00058,K01754,K04517,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,1.3.1.12,4.3.1.19 0.000000000000000000000000000000000000000000000001295 183.0
HFD2_k127_194835_9 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000000000000000000000004178 109.0
HFD2_k127_1958412_0 efflux transmembrane transporter activity - - - 1.39e-208 676.0
HFD2_k127_1958412_1 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 580.0
HFD2_k127_1958412_2 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005864 250.0
HFD2_k127_1958412_3 efflux transmembrane transporter activity - - - 0.0000000000000009141 79.0
HFD2_k127_1966739_0 B12 binding domain - - - 3.164e-196 640.0
HFD2_k127_1966739_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000002633 158.0
HFD2_k127_1966739_5 Phosphopantetheine attachment site K02078 - - 0.000000000000008303 78.0
HFD2_k127_1966739_6 polysaccharide deacetylase K01452 - 3.5.1.41 0.000000000001219 79.0
HFD2_k127_1966739_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000009654 59.0
HFD2_k127_1983059_0 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 353.0
HFD2_k127_1983059_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 306.0
HFD2_k127_1983059_2 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000004517 197.0
HFD2_k127_1983059_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000003448 145.0
HFD2_k127_1983059_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000873 138.0
HFD2_k127_1983059_5 Tetratricopeptide repeat - - - 0.00000000000000000000001619 116.0
HFD2_k127_1983059_6 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000007235 97.0
HFD2_k127_1983059_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000002114 102.0
HFD2_k127_1984073_0 Dehydrogenase E1 component K11381 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 619.0
HFD2_k127_1984073_1 AAA domain K01090 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 428.0
HFD2_k127_1984073_2 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K17763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 409.0
HFD2_k127_1984073_3 PFAM regulatory protein LuxR - - - 0.0000000000000000000000000000000000000000000000000000000000008742 216.0
HFD2_k127_1984073_4 STAS domain K17762 - - 0.0000000000000000000000000000000000000001344 165.0
HFD2_k127_1984073_5 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000002165 154.0
HFD2_k127_1984073_6 Histidine kinase-like ATPase domain K17752 - 2.7.11.1 0.000000000000000000000000000000000000001628 159.0
HFD2_k127_1984073_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000002372 162.0
HFD2_k127_1984073_8 Stage II sporulation protein E K05518 - 3.1.3.3 0.0000000000000000000000000000000000002213 154.0
HFD2_k127_1988465_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 9.805e-240 761.0
HFD2_k127_1988465_1 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 498.0
HFD2_k127_1988465_10 Cytochrome c - - - 0.000000000000000000000000001661 121.0
HFD2_k127_1988465_11 to Cytochrome c-554 precursor (C554) (Hydroxylamine oxidoreductase-linked cytochrome) pir A59036 cytochrome c554, tetraheme, precursor - Nitrosomonas europaea - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000005545 115.0
HFD2_k127_1988465_12 - - - - 0.0000000004533 64.0
HFD2_k127_1988465_13 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.00006128 51.0
HFD2_k127_1988465_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009295 423.0
HFD2_k127_1988465_3 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 408.0
HFD2_k127_1988465_4 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 315.0
HFD2_k127_1988465_5 response regulator K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006664 256.0
HFD2_k127_1988465_7 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000000005916 228.0
HFD2_k127_1988465_8 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000002224 223.0
HFD2_k127_1988465_9 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000373 175.0
HFD2_k127_2080896_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009225 637.0
HFD2_k127_2080896_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008424 583.0
HFD2_k127_2080896_2 belongs to the thioredoxin family K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 450.0
HFD2_k127_2080896_3 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 442.0
HFD2_k127_2080896_4 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 327.0
HFD2_k127_2080896_5 SpoIVB peptidase S55 K00973,K02414,K21449 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 326.0
HFD2_k127_2080896_6 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000001717 158.0
HFD2_k127_2080896_7 CarboxypepD_reg-like domain - - - 0.0000000000000000009704 103.0
HFD2_k127_2080896_8 repeat-containing protein - - - 0.0000000004965 74.0
HFD2_k127_2080896_9 amino acid activation for nonribosomal peptide biosynthetic process K01183 - 3.2.1.14 0.0000002963 63.0
HFD2_k127_208804_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 327.0
HFD2_k127_208804_1 protein conserved in bacteria - - - 0.00000000000000000094 102.0
HFD2_k127_2092071_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03851,K15372 - 2.6.1.55,2.6.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005313 475.0
HFD2_k127_2092071_1 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007615 322.0
HFD2_k127_2092071_2 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 314.0
HFD2_k127_2092071_3 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000006524 183.0
HFD2_k127_2099307_0 Thrombospondin type 3 - - - 0.00000000000000000000000000001025 138.0
HFD2_k127_213318_0 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 439.0
HFD2_k127_213318_1 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000001567 243.0
HFD2_k127_213318_2 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000004228 222.0
HFD2_k127_213318_3 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000001826 120.0
HFD2_k127_2156760_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 3.225e-195 640.0
HFD2_k127_2156760_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 544.0
HFD2_k127_2156760_2 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 542.0
HFD2_k127_2156760_3 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 383.0
HFD2_k127_2156760_4 Transmembrane and TPR repeat-containing protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0008150,GO:0012505,GO:0016020,GO:0031984,GO:0042175,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0048878,GO:0050801,GO:0055065,GO:0055074,GO:0055080,GO:0065007,GO:0065008,GO:0072507,GO:0098771,GO:0098827 - 0.000000000000000000000000000000000000000000000001855 197.0
HFD2_k127_2156760_5 UbiA prenyltransferase family - - - 0.0000000003412 61.0
HFD2_k127_2171141_0 Heat shock 70 kDa protein K04043 - - 2.941e-231 731.0
HFD2_k127_2171141_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 405.0
HFD2_k127_2171141_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 381.0
HFD2_k127_2171141_3 Carbon-nitrogen hydrolase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 331.0
HFD2_k127_2171141_4 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001443 280.0
HFD2_k127_2171141_5 Methylates ribosomal protein L11 K02687 - - 0.000000000000000000000000000000000005015 150.0
HFD2_k127_2171141_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.00000000000000000000000000000003442 134.0
HFD2_k127_2171707_0 Tetratricopeptide repeat K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001447 282.0
HFD2_k127_2171707_1 Di-haem cytochrome c peroxidase - - - 0.000000000000000000000000000000000000000000000000000006287 198.0
HFD2_k127_2171707_2 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000003379 186.0
HFD2_k127_2171707_3 Protein of unknown function (DUF2585) - - - 0.0000000000000000000000000000000000000000000000004646 182.0
HFD2_k127_2203232_0 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 395.0
HFD2_k127_2244206_0 PFAM glycosyl transferase family 39 - - - 0.000000000000028 87.0
HFD2_k127_2244206_1 Sulfatase K01133 - 3.1.6.6 0.00003595 54.0
HFD2_k127_2254850_0 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006987 562.0
HFD2_k127_2254850_1 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000003118 229.0
HFD2_k127_2254850_2 Belongs to the peptidase S41A family - - - 0.0000000000000000000000002981 108.0
HFD2_k127_2267134_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000004568 105.0
HFD2_k127_2267134_1 peptidyl-tyrosine sulfation - - - 0.00000000006293 64.0
HFD2_k127_2312379_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.781e-250 797.0
HFD2_k127_2312379_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 5.057e-228 736.0
HFD2_k127_2312379_10 Protein of unknown function (DUF503) K09764 - - 0.00000000000000006911 84.0
HFD2_k127_2312379_2 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007235 407.0
HFD2_k127_2312379_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000006161 221.0
HFD2_k127_2312379_4 AMMECR1 K06990,K09141 - - 0.00000000000000000000000000000000000000000000419 171.0
HFD2_k127_2312379_5 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000004265 147.0
HFD2_k127_2312379_6 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000003093 119.0
HFD2_k127_2312379_7 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000003061 117.0
HFD2_k127_2312379_8 - - - - 0.0000000000000000000002454 104.0
HFD2_k127_2312379_9 General secretory system II protein E domain protein K02652 - - 0.0000000000000000000002761 113.0
HFD2_k127_233318_0 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 3.501e-196 634.0
HFD2_k127_233318_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006026 577.0
HFD2_k127_233318_10 biopolymer transport protein K03559,K03560 - - 0.0000000000000000000009711 100.0
HFD2_k127_233318_11 TIGRFAM TonB K03832 - - 0.00000000000000000006523 100.0
HFD2_k127_233318_12 nuclear chromosome segregation - - - 0.0000000000000000002293 100.0
HFD2_k127_233318_13 peptidyl-tyrosine sulfation - - - 0.00000000000001555 87.0
HFD2_k127_233318_14 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03087 - - 0.00001879 54.0
HFD2_k127_233318_15 Tetratricopeptide repeat - - - 0.0002084 52.0
HFD2_k127_233318_2 Belongs to the MurCDEF family K01921,K01924,K02558 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0042802,GO:0044424,GO:0044464 6.3.2.4,6.3.2.45,6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 478.0
HFD2_k127_233318_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000001072 250.0
HFD2_k127_233318_4 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000003504 223.0
HFD2_k127_233318_5 MotA TolQ ExbB proton channel K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000000000002013 220.0
HFD2_k127_233318_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000006696 219.0
HFD2_k127_233318_7 methyltransferase activity K21310 - 2.1.1.334 0.000000000000000000000000000000001936 139.0
HFD2_k127_233318_8 Fibronectin type 3 domain - - - 0.0000000000000000000000009989 118.0
HFD2_k127_233318_9 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000001121 102.0
HFD2_k127_2340479_0 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 543.0
HFD2_k127_2340479_1 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008091 439.0
HFD2_k127_2340479_2 DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000002525 254.0
HFD2_k127_2340479_3 peptidase - - - 0.0000000000000000000000000000000000000000000000002224 182.0
HFD2_k127_2340479_4 Tetratricopeptide TPR_2 repeat protein - - - 0.0001366 55.0
HFD2_k127_2354059_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 515.0
HFD2_k127_2354059_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 481.0
HFD2_k127_2354059_2 COG3119 Arylsulfatase A and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004364 270.0
HFD2_k127_2354059_3 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000005155 166.0
HFD2_k127_2354059_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000009281 130.0
HFD2_k127_2354059_5 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000003117 109.0
HFD2_k127_2354059_6 - - - - 0.00000000000345 75.0
HFD2_k127_2358740_0 His Kinase A (phosphoacceptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006538 393.0
HFD2_k127_2358740_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000896 288.0
HFD2_k127_2358740_2 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006156 272.0
HFD2_k127_2358740_3 decarboxylase K13745 - 4.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000002049 256.0
HFD2_k127_236090_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.825e-240 761.0
HFD2_k127_236090_1 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008174 595.0
HFD2_k127_236090_2 Similarity to COG0471 Di- and tricarboxylate transporters(Evalue K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 355.0
HFD2_k127_236090_3 TPR repeat-containing protein - - - 0.000000000000000000000000000000000002119 161.0
HFD2_k127_236090_4 Thioredoxin-like - - - 0.000000000001151 68.0
HFD2_k127_236090_5 Thioredoxin-like - - - 0.00000008033 55.0
HFD2_k127_237836_0 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000008696 221.0
HFD2_k127_237836_1 Putative metal-binding motif - - - 0.0000000000000000008109 102.0
HFD2_k127_237836_2 Tetratricopeptide repeat - - - 0.000000000000002671 83.0
HFD2_k127_2444433_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005139 341.0
HFD2_k127_2472426_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.952e-311 973.0
HFD2_k127_247829_0 Nitrite and sulphite reductase 4Fe-4S domain K00362,K00392 - 1.7.1.15,1.8.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 482.0
HFD2_k127_247829_1 Belongs to the precorrin methyltransferase family K02303 - 2.1.1.107 0.0000000000000000000000000000000000000000000000000000000000007579 226.0
HFD2_k127_247829_2 - - - - 0.0000000000000000000000000000000000000000000000000005515 194.0
HFD2_k127_247829_3 Sirohaem synthase dimerisation region K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000007205 154.0
HFD2_k127_247829_4 Glycosyl transferase family 2 - - - 0.00000000000000000001586 104.0
HFD2_k127_2541655_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000001228 239.0
HFD2_k127_2541655_1 PFAM Single-stranded nucleic acid binding R3H K06346 - - 0.000000000000000000006329 101.0
HFD2_k127_2548382_0 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 563.0
HFD2_k127_2548382_1 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 324.0
HFD2_k127_2548382_2 TIGRFAM hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009893 252.0
HFD2_k127_2548382_3 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000307 150.0
HFD2_k127_2548382_4 amine dehydrogenase activity - - - 0.00000000000000000000000000000001266 145.0
HFD2_k127_2548382_5 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000007466 123.0
HFD2_k127_2548382_6 chlorophyll binding - - - 0.000000000000000000000000001839 127.0
HFD2_k127_2548382_7 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000004499 104.0
HFD2_k127_2548382_8 Domain of unknown function (DUF309) K09763 - - 0.0000000000000000000518 94.0
HFD2_k127_2664213_0 heat shock protein DnaJ domain protein K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000001758 230.0
HFD2_k127_2664213_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0006807,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0020037,GO:0042279,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046906,GO:0048037,GO:0055114,GO:0097159,GO:0097164,GO:0098809,GO:1901363 - 0.00000000000000000000000000002714 135.0
HFD2_k127_2664213_2 MerR HTH family regulatory protein - - - 0.00000000004796 67.0
HFD2_k127_2684532_0 PFAM von Willebrand factor type A - - - 0.0000000000000000000000003747 121.0
HFD2_k127_2684532_1 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000008884 93.0
HFD2_k127_2684532_2 Ankyrin repeats (many copies) K21440 GO:0006810,GO:0008150,GO:0016192,GO:0016197,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0098876,GO:1990126 - 0.00000001034 68.0
HFD2_k127_2684532_3 PgaD-like protein K11937 - - 0.0000552 56.0
HFD2_k127_2684532_4 peptidyl-tyrosine sulfation - - - 0.0001525 47.0
HFD2_k127_2689094_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 408.0
HFD2_k127_2689094_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000004815 186.0
HFD2_k127_2689094_2 Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000212 165.0
HFD2_k127_2704080_0 LacY proton/sugar symporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 312.0
HFD2_k127_2704080_1 PFAM FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000000000000002308 85.0
HFD2_k127_2704080_2 ubiE/COQ5 methyltransferase family - - - 0.000000001677 64.0
HFD2_k127_2704646_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 581.0
HFD2_k127_2704646_1 GMP synthase (glutamine-hydrolyzing) activity K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000675 201.0
HFD2_k127_2716755_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 560.0
HFD2_k127_2716755_1 DNA polymerase III subunits gamma and tau domain III K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 377.0
HFD2_k127_2716755_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003704 268.0
HFD2_k127_2716755_3 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000001008 206.0
HFD2_k127_2716755_4 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000004654 155.0
HFD2_k127_2716755_5 DoxX K15977 - - 0.00000000000000000000000000000003105 132.0
HFD2_k127_2716755_6 AAA-like domain - - - 0.000000000000000000000000007527 126.0
HFD2_k127_2716755_7 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000163 88.0
HFD2_k127_271857_0 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000003746 66.0
HFD2_k127_271857_1 Tetratricopeptide repeat - - - 0.000001818 60.0
HFD2_k127_2721256_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1115.0
HFD2_k127_2721256_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000104 261.0
HFD2_k127_2721256_2 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000005924 218.0
HFD2_k127_2721256_3 protein conserved in bacteria K09984 - - 0.000000000000000000000000000000000000000000001026 179.0
HFD2_k127_2721256_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000001868 148.0
HFD2_k127_2721256_5 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000004399 159.0
HFD2_k127_2721256_6 - - - - 0.000000000000000000000000000000001578 145.0
HFD2_k127_2721256_7 peptidyl-tyrosine sulfation - - - 0.0000000000000000000001343 113.0
HFD2_k127_2721256_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000001214 93.0
HFD2_k127_2736247_0 Pfam:HxxPF_rpt - - - 1.57e-211 686.0
HFD2_k127_2742049_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.536e-260 829.0
HFD2_k127_2742049_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 373.0
HFD2_k127_2742049_2 signal sequence binding K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004443 285.0
HFD2_k127_2742049_3 cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001289 258.0
HFD2_k127_2742049_4 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000000000000002154 99.0
HFD2_k127_2742049_5 Domain of unknown function (DUF4382) - - - 0.0000000000000004667 86.0
HFD2_k127_2742049_6 - - - - 0.00000000001582 67.0
HFD2_k127_2743267_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 6.95e-252 797.0
HFD2_k127_2743267_1 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 609.0
HFD2_k127_2743267_10 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000001875 139.0
HFD2_k127_2743267_11 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000001392 134.0
HFD2_k127_2743267_12 FMN_bind - - - 0.00000000000000000000000000009923 124.0
HFD2_k127_2743267_13 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000003631 119.0
HFD2_k127_2743267_14 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.000000000000000001843 91.0
HFD2_k127_2743267_15 Pilus assembly protein, PilO K02664 - - 0.000000000000000001872 93.0
HFD2_k127_2743267_16 Tetratricopeptide repeat - - - 0.00000000000000001533 94.0
HFD2_k127_2743267_17 Ribosomal L28 family K02902 - - 0.00000000000000001642 85.0
HFD2_k127_2743267_19 tetratricopeptide repeat - - - 0.000000000002915 79.0
HFD2_k127_2743267_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 411.0
HFD2_k127_2743267_20 PFAM Fimbrial assembly family protein K02663 - - 0.00000000002363 74.0
HFD2_k127_2743267_21 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000003718 58.0
HFD2_k127_2743267_23 Roadblock/LC7 domain K07131 - - 0.00008475 53.0
HFD2_k127_2743267_3 Secretin and TonB N terminus short domain K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 376.0
HFD2_k127_2743267_4 pilus assembly protein K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004361 339.0
HFD2_k127_2743267_5 - K12065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 325.0
HFD2_k127_2743267_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000015 259.0
HFD2_k127_2743267_7 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000009367 160.0
HFD2_k127_2743267_8 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000007277 152.0
HFD2_k127_2743267_9 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000002093 140.0
HFD2_k127_2754109_0 PFAM HhH-GPD family protein K07457 - - 0.000000000000000000000000000000000000000000000000000000000178 215.0
HFD2_k127_2754109_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000005676 98.0
HFD2_k127_2754109_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.000004083 57.0
HFD2_k127_2763969_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 495.0
HFD2_k127_2763969_1 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007117 363.0
HFD2_k127_2763969_2 LAO AO transport system K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002462 303.0
HFD2_k127_2763969_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000002675 145.0
HFD2_k127_2763969_4 arylsulfatase activity K01133 - 3.1.6.6 0.0000000000000000000000000000008387 129.0
HFD2_k127_2769164_0 Prolyl oligopeptidase family - - - 6.999e-255 826.0
HFD2_k127_2769164_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 1.404e-253 808.0
HFD2_k127_2769164_10 OsmC-like protein K04063 - - 0.000000000000000000000000000000000000005229 150.0
HFD2_k127_2769164_11 AMP binding - - - 0.0000000000000000000000001996 111.0
HFD2_k127_2769164_12 Patatin-like phospholipase K07001 - - 0.0000000548 64.0
HFD2_k127_2769164_13 Rhodanese Homology Domain - - - 0.000001533 53.0
HFD2_k127_2769164_14 Ion transport K08713 - - 0.000003988 58.0
HFD2_k127_2769164_2 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000886 430.0
HFD2_k127_2769164_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 355.0
HFD2_k127_2769164_4 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009927 322.0
HFD2_k127_2769164_5 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 298.0
HFD2_k127_2769164_6 Belongs to the peptidase S51 family K05995 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 0.00000000000000000000000000000000000000000000000000000000000000000000004463 263.0
HFD2_k127_2769164_7 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000005232 250.0
HFD2_k127_2769164_8 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000115 258.0
HFD2_k127_2769164_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002259 239.0
HFD2_k127_2787128_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009084 279.0
HFD2_k127_2787128_1 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000001019 199.0
HFD2_k127_2787128_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000004224 204.0
HFD2_k127_2787128_3 - - - - 0.000000000000000000000000000000000000000000000000001598 193.0
HFD2_k127_2787128_4 Signal transduction histidine kinase, nitrogen specific, NtrB K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000006965 186.0
HFD2_k127_2787128_5 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000001711 115.0
HFD2_k127_2787128_6 pilus assembly protein PilW K01342,K02672,K20276 - 3.4.21.62 0.0000000183 67.0
HFD2_k127_2787128_7 Prokaryotic N-terminal methylation motif K02671 - - 0.000005756 55.0
HFD2_k127_2787128_8 Tfp pilus assembly protein FimT K08084,K08085 - - 0.0006609 49.0
HFD2_k127_2787128_9 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01218 - 3.2.1.78 0.0007001 52.0
HFD2_k127_2796255_0 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007798 356.0
HFD2_k127_2796255_1 thiamine diphosphate biosynthetic process K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005791 351.0
HFD2_k127_2796255_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008014 347.0
HFD2_k127_2796255_3 carboxylic acid catabolic process K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009712,GO:0009987,GO:0016853,GO:0016854,GO:0016872,GO:0018850,GO:0018958,GO:0019336,GO:0019439,GO:0019614,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044248,GO:0046872,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901575,GO:1901615,GO:1901616 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000004322 238.0
HFD2_k127_2796255_4 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000001723 178.0
HFD2_k127_2796255_5 - - - - 0.0000000000000000000000000009545 122.0
HFD2_k127_2796255_6 Thiamine biosynthesis K03154 - - 0.000000001077 69.0
HFD2_k127_2813184_0 Protein kinase domain K12132 - 2.7.11.1 4.499e-224 749.0
HFD2_k127_2813184_1 Involved in the tonB-independent uptake of proteins - - - 1.504e-211 701.0
HFD2_k127_2813184_10 RNA recognition motif - - - 0.000000000000000000001336 99.0
HFD2_k127_2813184_11 PFAM Rh family protein ammonium transporter K03320 - - 0.00000000000000000005697 91.0
HFD2_k127_2813184_12 - - - - 0.00000000000004723 85.0
HFD2_k127_2813184_13 STAS domain K04749 - - 0.00000001276 63.0
HFD2_k127_2813184_14 - - - - 0.0000001994 54.0
HFD2_k127_2813184_15 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0004335 46.0
HFD2_k127_2813184_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 620.0
HFD2_k127_2813184_3 Peptidase dimerisation domain K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 489.0
HFD2_k127_2813184_4 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 406.0
HFD2_k127_2813184_5 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000192 180.0
HFD2_k127_2813184_6 Domain of unknown function (DUF4347) K20276 - - 0.00000000000000000000000000000000001204 154.0
HFD2_k127_2813184_7 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000004865 137.0
HFD2_k127_2813184_8 Ribonuclease B OB domain K03704 - - 0.000000000000000000000000004425 112.0
HFD2_k127_2813184_9 Uncharacterised protein family (UPF0158) - - - 0.000000000000000000000002182 105.0
HFD2_k127_2836351_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568 523.0
HFD2_k127_2836351_1 TRAP transporter T-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 298.0
HFD2_k127_2836351_2 carbohydrate transport K11688,K21395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000133 276.0
HFD2_k127_2836351_3 - - - - 0.00000000006321 67.0
HFD2_k127_2888133_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 557.0
HFD2_k127_2888133_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006861 335.0
HFD2_k127_289408_0 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 317.0
HFD2_k127_289408_1 Cold shock K03704 - - 0.0000000000009464 71.0
HFD2_k127_289408_2 Periplasmic component of the Tol biopolymer transport system - - - 0.000000005816 67.0
HFD2_k127_2897705_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 2.423e-309 973.0
HFD2_k127_2897705_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 356.0
HFD2_k127_2897705_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 320.0
HFD2_k127_2897705_3 GTP binding K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006793 267.0
HFD2_k127_2897705_4 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000001448 255.0
HFD2_k127_2897705_5 Metallo-beta-lactamase superfamily K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000003184 265.0
HFD2_k127_2897705_6 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000001465 220.0
HFD2_k127_2897705_7 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000001016 201.0
HFD2_k127_2897705_8 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000236 119.0
HFD2_k127_2897705_9 outer membrane autotransporter barrel domain protein - - - 0.0000000000000002658 91.0
HFD2_k127_290315_0 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 392.0
HFD2_k127_290315_1 Peptidase M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 323.0
HFD2_k127_290315_2 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000001317 258.0
HFD2_k127_290315_3 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000001963 262.0
HFD2_k127_290315_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000007454 256.0
HFD2_k127_290315_5 IMG reference gene - - - 0.0000000000000000000000000000000000000000005723 179.0
HFD2_k127_290315_6 Yqey-like protein K09117 - - 0.00000000000000000000000005111 117.0
HFD2_k127_2912019_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.14e-287 911.0
HFD2_k127_2912019_1 PFAM Type II secretion system protein E K02652 - - 6.238e-223 703.0
HFD2_k127_2912019_10 Belongs to the RimK family K05827,K05844 - 6.3.2.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000006695 265.0
HFD2_k127_2912019_11 ATP:dephospho-CoA triphosphoribosyl transferase K05966 - 2.4.2.52 0.00000000000000000000000000000000000000000000000000000000000000001336 246.0
HFD2_k127_2912019_12 transferase activity, transferring glycosyl groups K06984 - 2.4.2.54 0.0000000000000000000000000000000000000000000000000000000253 217.0
HFD2_k127_2912019_13 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000317 205.0
HFD2_k127_2912019_14 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946,K07123 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.000000000000000000000000000000000000000000000000000001643 208.0
HFD2_k127_2912019_15 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000002953 201.0
HFD2_k127_2912019_16 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000003298 192.0
HFD2_k127_2912019_17 Amino acid kinase family K12524 - 1.1.1.3,2.7.2.4 0.00000000000000000000000000000000000000000000000003106 187.0
HFD2_k127_2912019_18 - - - - 0.00000000000000000000000000000000000000000000493 181.0
HFD2_k127_2912019_19 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000001022 161.0
HFD2_k127_2912019_2 Formylmethanofuran dehydrogenase subunit A K00200 GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0044237,GO:0044281 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 481.0
HFD2_k127_2912019_20 formylmethanofuran dehydrogenase subunit C K00202 - 1.2.7.12 0.00000000000000000000000000000000000000006244 173.0
HFD2_k127_2912019_21 Protein of unknown function (DUF447) K09154 - - 0.0000000000000000000000000000000002908 144.0
HFD2_k127_2912019_22 - K00201 GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0044237,GO:0044281 1.2.7.12 0.0000000000000000000000000000001856 139.0
HFD2_k127_2912019_23 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000001497 134.0
HFD2_k127_2912019_24 type II secretion system protein G K02456 - - 0.00000000000000000000000003999 114.0
HFD2_k127_2912019_25 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000002136 111.0
HFD2_k127_2912019_26 Alpha beta hydrolase - - - 0.0000000000000000000007056 108.0
HFD2_k127_2912019_27 sigma-70 region 2 domain protein K03088 - - 0.0000000000000000009458 102.0
HFD2_k127_2912019_28 Pilus assembly protein K02662 - - 0.0000000000000000384 93.0
HFD2_k127_2912019_29 - - - - 0.00000000000006696 77.0
HFD2_k127_2912019_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 449.0
HFD2_k127_2912019_30 general secretion pathway protein K02456,K02650 - - 0.000000000005697 79.0
HFD2_k127_2912019_31 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 GO:0003674,GO:0003824,GO:0004150,GO:0005488,GO:0005515,GO:0016829,GO:0016830,GO:0016832,GO:0042802 1.13.11.81,4.1.2.25,5.1.99.8 0.00000162 55.0
HFD2_k127_2912019_32 general secretion pathway protein K02453 - - 0.00001492 55.0
HFD2_k127_2912019_33 carbon utilization K02664,K02665 - - 0.00009842 55.0
HFD2_k127_2912019_34 PFAM Fimbrial assembly family protein K02663 - - 0.0007566 52.0
HFD2_k127_2912019_4 beta-lactamase domain protein K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 387.0
HFD2_k127_2912019_5 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 374.0
HFD2_k127_2912019_6 Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) K00672 GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0030270,GO:0043446,GO:0044237,GO:0044281,GO:0071704 2.3.1.101 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 356.0
HFD2_k127_2912019_7 Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT K01499 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016787,GO:0016810,GO:0016814,GO:0018759,GO:0019238,GO:0043446,GO:0044237,GO:0044424,GO:0044464,GO:0071704 3.5.4.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008101 310.0
HFD2_k127_2912019_8 Type ii and iii secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 327.0
HFD2_k127_2912019_9 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 297.0
HFD2_k127_292253_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 1.371e-206 673.0
HFD2_k127_292253_1 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 447.0
HFD2_k127_292253_2 ABC 3 transport family K02075,K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006022 297.0
HFD2_k127_292253_3 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002511 264.0
HFD2_k127_292253_4 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000003414 243.0
HFD2_k127_292253_5 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000000000000000000000006743 187.0
HFD2_k127_292253_6 Kazal-type serine protease inhibitor domain - - - 0.000000000000000000000000000000000007997 139.0
HFD2_k127_292253_7 Staphylococcal nuclease homologues K01174,K01286 - 3.1.31.1,3.4.16.4 0.00000000000000000000000000000000228 134.0
HFD2_k127_292253_8 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000005627 132.0
HFD2_k127_292253_9 PilZ domain - - - 0.0000898 51.0
HFD2_k127_2933012_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 353.0
HFD2_k127_2933012_1 e3 binding domain K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007536 317.0
HFD2_k127_2933012_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000003116 212.0
HFD2_k127_2981793_0 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000705 459.0
HFD2_k127_2981793_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000007491 116.0
HFD2_k127_2981793_2 Putative zinc-finger - - - 0.00001839 57.0
HFD2_k127_3007939_0 PFAM MMPL family K07003 - - 7.676e-214 694.0
HFD2_k127_3007939_1 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000009645 211.0
HFD2_k127_3007939_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000006861 168.0
HFD2_k127_3067149_0 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008059 289.0
HFD2_k127_3067149_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003867 260.0
HFD2_k127_3067149_2 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000007234 224.0
HFD2_k127_3067149_3 ribonuclease BN K07058 - - 0.0000000000000000000000000000000000000000000000000000000511 206.0
HFD2_k127_3067149_4 Methyltransferase FkbM domain - - - 0.0000000000000000000000000000000000000000000000000000006269 205.0
HFD2_k127_3067149_5 Protein involved in cellulose biosynthesis - - - 0.000000000000000000000000000000000000000003612 173.0
HFD2_k127_3067149_6 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000001606 143.0
HFD2_k127_3067149_7 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000002491 131.0
HFD2_k127_3067149_8 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000003913 70.0
HFD2_k127_306802_0 Flavin containing amine oxidoreductase K00231,K01854 - 1.3.3.15,1.3.3.4,5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 396.0
HFD2_k127_306802_1 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 319.0
HFD2_k127_306802_2 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000001903 186.0
HFD2_k127_306802_3 transferase activity, transferring glycosyl groups - - - 0.0000000004539 72.0
HFD2_k127_307361_0 prohibitin homologues K07192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 517.0
HFD2_k127_307361_1 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000005457 156.0
HFD2_k127_307361_2 PhoPQ-activated pathogenicity-related protein - - - 0.0000000000000000000000000000001129 130.0
HFD2_k127_307361_4 Membrane protein implicated in regulation of membrane protease activity - - - 0.0000000006594 68.0
HFD2_k127_3123416_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004941 400.0
HFD2_k127_3123416_1 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 371.0
HFD2_k127_3123416_2 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 313.0
HFD2_k127_3123416_3 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.0000000000000005323 81.0
HFD2_k127_3123416_4 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000001322 74.0
HFD2_k127_3174427_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 582.0
HFD2_k127_3174427_1 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001463 267.0
HFD2_k127_3174427_2 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000001053 197.0
HFD2_k127_3174427_3 Part of the ABC transporter FtsEX involved in K09811 - - 0.0000000000000000000000000000009229 139.0
HFD2_k127_3182455_0 NUBPL iron-transfer P-loop NTPase K16554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 330.0
HFD2_k127_3182455_1 O-Antigen ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007251 272.0
HFD2_k127_3182455_2 6-phosphogluconolactonase activity K01991,K20987 - - 0.00000000000000000000000000000001374 144.0
HFD2_k127_3182455_3 Glycosyl transferases group 1 - - - 0.0000000000007237 82.0
HFD2_k127_3182455_4 PFAM Polysaccharide biosynthesis protein - - - 0.000000002411 71.0
HFD2_k127_3182455_5 Peptidase S24-like K13280 - 3.4.21.89 0.000009528 58.0
HFD2_k127_3231436_0 MviN-like protein K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 378.0
HFD2_k127_3231436_1 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 313.0
HFD2_k127_3231824_0 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009892 265.0
HFD2_k127_3231824_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000146 252.0
HFD2_k127_3231824_2 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000005022 226.0
HFD2_k127_3231824_3 Pfam ATP-grasp domain K06914 - 6.3.4.24 0.0000000000000000000000000000000000000000006104 171.0
HFD2_k127_3231824_4 Domain of unknown function (DUF814) - - - 0.000000000000000000000000000000000000000007791 173.0
HFD2_k127_3231824_5 Hydantoinase/oxoprolinase K07072 - 2.5.1.131 0.000000000000000000000000000000000000003924 166.0
HFD2_k127_3231824_6 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000001945 159.0
HFD2_k127_3231824_7 CarD-like/TRCF domain K07736 - - 0.00000000000000000000000000000000000271 144.0
HFD2_k127_3231824_8 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.000000000000000000000000000000000009601 149.0
HFD2_k127_3231824_9 Glycosyl transferase, family 2 K12984 - - 0.000000000000000006256 89.0
HFD2_k127_3238404_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000001562 158.0
HFD2_k127_3238404_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000001508 104.0
HFD2_k127_3238404_2 Glycosyl transferase family 2 - - - 0.000000000000000006561 85.0
HFD2_k127_3257395_0 Oligoendopeptidase f - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 619.0
HFD2_k127_3257395_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000002395 242.0
HFD2_k127_3257395_2 EamA-like transporter family K08978 - - 0.000686 44.0
HFD2_k127_3291102_0 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 332.0
HFD2_k127_3291102_1 ABC transporter transmembrane region K06147 - - 0.00006194 57.0
HFD2_k127_3291102_2 helix_turn_helix, arabinose operon control protein - - - 0.0002472 53.0
HFD2_k127_3321645_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009552 530.0
HFD2_k127_3321645_1 sulfate adenylyltransferase K00958 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 452.0
HFD2_k127_3321645_2 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004555 278.0
HFD2_k127_3321645_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000746 237.0
HFD2_k127_3321645_4 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000115 165.0
HFD2_k127_3321645_5 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000004216 138.0
HFD2_k127_3321645_6 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000003597 127.0
HFD2_k127_3321645_7 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000006904 113.0
HFD2_k127_3330743_0 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 482.0
HFD2_k127_3330743_1 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001131 254.0
HFD2_k127_3330743_2 Putative adhesin - - - 0.000000000000000000000000000001287 136.0
HFD2_k127_3330743_3 BON domain K04065 GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 - 0.00000001096 61.0
HFD2_k127_3449814_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 522.0
HFD2_k127_3449814_1 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 394.0
HFD2_k127_3449814_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 397.0
HFD2_k127_3449814_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 372.0
HFD2_k127_3449814_4 Histidine kinase K02482,K03557 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000005282 246.0
HFD2_k127_3449814_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000001513 244.0
HFD2_k127_3449814_6 Lipase maturation factor - - - 0.00000000000000000000000000000001365 130.0
HFD2_k127_3449814_7 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000001998 134.0
HFD2_k127_3449814_8 - - - - 0.00000000004447 69.0
HFD2_k127_3449814_9 - - - - 0.0000000002636 73.0
HFD2_k127_3480051_0 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 479.0
HFD2_k127_3480051_1 proline dipeptidase activity K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 375.0
HFD2_k127_3480051_2 ATP ADP translocase K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007372 287.0
HFD2_k127_3480051_3 Squalene/phytoene synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000141 272.0
HFD2_k127_3480051_4 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000008341 234.0
HFD2_k127_3480051_5 TIGRFAM squalene-associated FAD-dependent desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000001345 236.0
HFD2_k127_3480051_6 guanyl-nucleotide exchange factor activity - - - 0.0000000000000000000000000000000178 145.0
HFD2_k127_3480051_7 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000009016 124.0
HFD2_k127_3480051_8 Polymer-forming cytoskeletal - - - 0.0000000003702 72.0
HFD2_k127_3480545_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 421.0
HFD2_k127_3480545_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 385.0
HFD2_k127_3493442_0 Bacterial membrane protein, YfhO - - - 0.00000000000000000002625 103.0
HFD2_k127_3493442_1 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000003784 95.0
HFD2_k127_3493442_2 general secretion pathway protein K02456 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000000001341 66.0
HFD2_k127_3504491_0 COG0843 Heme copper-type cytochrome quinol oxidases, subunit 1 K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005313 500.0
HFD2_k127_3504491_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 476.0
HFD2_k127_3504491_2 Heme copper-type cytochrome quinol oxidases, subunit 2 K02275 - 1.9.3.1 0.000000000000000000000000000000000000007254 153.0
HFD2_k127_3532481_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 6.5e-321 1009.0
HFD2_k127_3532481_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 415.0
HFD2_k127_3532481_10 Polymer-forming cytoskeletal - - - 0.0000000004342 72.0
HFD2_k127_3532481_11 photoreceptor activity - - - 0.00000006841 63.0
HFD2_k127_3532481_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 340.0
HFD2_k127_3532481_3 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 327.0
HFD2_k127_3532481_4 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004011 241.0
HFD2_k127_3532481_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000005172 218.0
HFD2_k127_3532481_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000001965 150.0
HFD2_k127_3532481_7 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000005765 145.0
HFD2_k127_3532481_8 cheY-homologous receiver domain K07668 - - 0.000000000000000000000000001066 116.0
HFD2_k127_3532481_9 histone H2A K63-linked ubiquitination - - - 0.000000000000000009705 96.0
HFD2_k127_3555241_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 328.0
HFD2_k127_3555241_1 dipeptide transport K02035 - - 0.00000000001735 71.0
HFD2_k127_3569203_0 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002678 269.0
HFD2_k127_3569203_1 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000003639 225.0
HFD2_k127_3581812_0 PFAM peptidase M13 K01415 - 3.4.24.71 1.036e-198 647.0
HFD2_k127_3581812_1 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 592.0
HFD2_k127_3581812_2 Peptidase dimerisation domain K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 398.0
HFD2_k127_3581812_3 CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008109 273.0
HFD2_k127_3581812_4 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000003427 236.0
HFD2_k127_3581812_5 - - - - 0.00000000000000001258 96.0
HFD2_k127_3581812_6 Belongs to the ompA family K03286 - - 0.0001067 52.0
HFD2_k127_3583462_0 Amino acid adenylation enzyme thioester reductase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008525 495.0
HFD2_k127_3583462_1 non-ribosomal peptide synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003764 278.0
HFD2_k127_3583483_0 Amino acid adenylation enzyme thioester reductase family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 311.0
HFD2_k127_3583483_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000001173 256.0
HFD2_k127_3583483_2 - - - - 0.00000000000002068 82.0
HFD2_k127_3583483_3 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.0000000009607 73.0
HFD2_k127_3593218_0 copper-translocating P-type ATPase K17686 - 3.6.3.54 9.443e-268 849.0
HFD2_k127_3593218_1 glyoxalase III activity - - - 0.00000000005476 74.0
HFD2_k127_3593218_2 PD-(D/E)XK nuclease superfamily - - - 0.00000000149 66.0
HFD2_k127_3598118_0 Cytochrome C assembly protein K02198,K04016 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 618.0
HFD2_k127_3598118_1 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008961 296.0
HFD2_k127_3598118_10 subunit of a heme lyase K02200 - - 0.000000000000002317 84.0
HFD2_k127_3598118_11 Transposase IS200 like - - - 0.0000002072 61.0
HFD2_k127_3598118_12 - - - - 0.0001936 52.0
HFD2_k127_3598118_13 deoxyhypusine monooxygenase activity - - - 0.000633 51.0
HFD2_k127_3598118_2 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000000005041 224.0
HFD2_k127_3598118_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000001235 220.0
HFD2_k127_3598118_4 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000001176 193.0
HFD2_k127_3598118_5 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000002789 194.0
HFD2_k127_3598118_6 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.00000000000000000000000000000000000000000000327 178.0
HFD2_k127_3598118_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000006598 168.0
HFD2_k127_3598118_8 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000002872 117.0
HFD2_k127_3598118_9 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000002117 92.0
HFD2_k127_3598233_0 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 520.0
HFD2_k127_3598233_1 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 533.0
HFD2_k127_3598233_10 PFAM Formiminotransferase-cyclodeaminase - - - 0.00000000000000000000000000000000007499 142.0
HFD2_k127_3598233_11 Reverse transcriptase-like K03469,K06864,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.00000000000000000000000000001101 129.0
HFD2_k127_3598233_12 DivIVA protein K04074 - - 0.0000000000000000000001236 111.0
HFD2_k127_3598233_13 C4-type zinc ribbon domain K07164 - - 0.00000000000000006438 92.0
HFD2_k127_3598233_14 - - - - 0.0000000000000003111 81.0
HFD2_k127_3598233_15 Subtilase family - - - 0.0000000000001191 86.0
HFD2_k127_3598233_16 BON domain - - - 0.0000000003077 72.0
HFD2_k127_3598233_2 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 484.0
HFD2_k127_3598233_3 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 442.0
HFD2_k127_3598233_4 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008774 389.0
HFD2_k127_3598233_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 303.0
HFD2_k127_3598233_6 PFAM regulatory protein LuxR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002414 283.0
HFD2_k127_3598233_7 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004169 256.0
HFD2_k127_3598233_8 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000001449 202.0
HFD2_k127_3598233_9 Protein of unknown function (DUF2860) - - - 0.000000000000000000000000000000000000004654 159.0
HFD2_k127_3599615_0 non-ribosomal peptide synthetase - - - 0.0 1413.0
HFD2_k127_3601219_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.697e-219 700.0
HFD2_k127_3601219_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 510.0
HFD2_k127_3601219_2 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 424.0
HFD2_k127_3601219_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009123 296.0
HFD2_k127_3601219_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000000004509 205.0
HFD2_k127_3601219_5 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000001723 149.0
HFD2_k127_3601219_6 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000002219 89.0
HFD2_k127_3601219_7 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000001694 93.0
HFD2_k127_3601219_8 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0002339 51.0
HFD2_k127_3601322_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 329.0
HFD2_k127_3601322_1 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000006389 156.0
HFD2_k127_3601322_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000007075 158.0
HFD2_k127_3601322_3 Acyltransferase - - - 0.0000000000003779 80.0
HFD2_k127_3605866_0 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 5.76e-260 816.0
HFD2_k127_3605866_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 372.0
HFD2_k127_3605866_2 Ion channel - - - 0.00000000000000000000000000000000004286 144.0
HFD2_k127_3605866_3 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000001096 92.0
HFD2_k127_3613665_0 benzoyl-CoA oxygenase K15512 - 1.14.13.208 7.924e-225 705.0
HFD2_k127_3613665_1 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 8.673e-223 703.0
HFD2_k127_3613665_10 WD40-like Beta Propeller Repeat - - - 0.00000009556 58.0
HFD2_k127_3613665_2 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 297.0
HFD2_k127_3613665_3 A G-specific K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001686 280.0
HFD2_k127_3613665_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891,K15546 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000000001029 237.0
HFD2_k127_3613665_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000454 204.0
HFD2_k127_3613665_6 COG0720 6-pyruvoyl-tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000004495 164.0
HFD2_k127_3613665_7 alpha beta - - - 0.00000000000000000000005272 115.0
HFD2_k127_3613665_8 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000003297 96.0
HFD2_k127_3640114_0 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006517 604.0
HFD2_k127_3640114_1 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 401.0
HFD2_k127_3640114_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 343.0
HFD2_k127_3640114_3 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 346.0
HFD2_k127_3640114_4 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 305.0
HFD2_k127_3640114_5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000003167 201.0
HFD2_k127_3640114_6 Ribosomal protein S9/S16 K02996 - - 0.000000000000000000000000000000000000000002489 162.0
HFD2_k127_3656891_0 AcrB/AcrD/AcrF family K03296 - - 2.5e-323 1020.0
HFD2_k127_3656891_1 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008383 342.0
HFD2_k127_3656891_2 COG0500 SAM-dependent methyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007295 261.0
HFD2_k127_3656891_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000004674 214.0
HFD2_k127_3656891_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000003092 215.0
HFD2_k127_3656891_5 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000000000003909 149.0
HFD2_k127_3656891_6 Glyoxalase-like domain K06996 - - 0.0000000000000000000000000000000003951 138.0
HFD2_k127_3656891_7 Regulatory protein, FmdB family - - - 0.0000000001647 70.0
HFD2_k127_3656891_8 PFAM glycosyl transferase group 1 - - - 0.000009805 58.0
HFD2_k127_3656891_9 CAAX protease self-immunity - - - 0.00002293 56.0
HFD2_k127_3712477_0 Thrombospondin type 3 repeat - - - 0.00002256 59.0
HFD2_k127_3712477_1 Belongs to the peptidase S8 family - - - 0.0002037 55.0
HFD2_k127_3735332_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 559.0
HFD2_k127_3735332_1 Peptidoglycan-binding domain 1 protein K07273 - - 0.00000000004076 68.0
HFD2_k127_3753238_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 478.0
HFD2_k127_3753238_1 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 396.0
HFD2_k127_3753238_2 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001735 291.0
HFD2_k127_3753238_3 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000001278 234.0
HFD2_k127_3753238_4 NlpC/P60 family - - - 0.000000000000000000000000000000000000000000000000000000000666 214.0
HFD2_k127_3753238_5 PFAM Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000002241 158.0
HFD2_k127_3753238_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000005645 160.0
HFD2_k127_3753238_7 Protein of unknown function (DUF983) - - - 0.00000000000000000000000004352 119.0
HFD2_k127_3753238_8 Putative regulatory protein - - - 0.000000000000000002016 89.0
HFD2_k127_3792150_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 1.202e-199 653.0
HFD2_k127_3792150_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 456.0
HFD2_k127_3792150_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 415.0
HFD2_k127_3792150_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005665 373.0
HFD2_k127_3792150_4 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000004279 274.0
HFD2_k127_3792150_5 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000001952 213.0
HFD2_k127_3792150_6 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000423 176.0
HFD2_k127_3792150_7 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000001261 162.0
HFD2_k127_3792150_8 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000001449 156.0
HFD2_k127_3792150_9 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000000000000002213 143.0
HFD2_k127_3793094_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000006553 222.0
HFD2_k127_3822719_0 Malic enzyme, NAD binding domain K00027,K00029,K00625,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 1.015e-304 966.0
HFD2_k127_3822719_1 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 559.0
HFD2_k127_3822719_10 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.000000000000000000000004597 105.0
HFD2_k127_3822719_11 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000005634 89.0
HFD2_k127_3822719_12 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000002741 79.0
HFD2_k127_3822719_13 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00001221 55.0
HFD2_k127_3822719_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175,K00177,K00187 - 1.2.7.11,1.2.7.3,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 524.0
HFD2_k127_3822719_3 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 438.0
HFD2_k127_3822719_4 alanine dehydrogenase activity K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 340.0
HFD2_k127_3822719_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 317.0
HFD2_k127_3822719_6 ribosomal rna small subunit methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 293.0
HFD2_k127_3822719_7 Ribosomal protein L11 methyltransferase (PrmA) K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000001453 267.0
HFD2_k127_3822719_8 methyltransferase - - - 0.0000000000000000000000000000000000000000008898 175.0
HFD2_k127_3822719_9 Glycosyl transferase, family 2 K13500 - 2.4.1.175,2.4.1.226 0.000000000000000000000000000000000000008141 158.0
HFD2_k127_3824168_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 617.0
HFD2_k127_3824168_1 Seven times multi-haem cytochrome CxxCH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009181 515.0
HFD2_k127_3824168_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 398.0
HFD2_k127_3824168_3 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000006678 246.0
HFD2_k127_3824168_4 - - - - 0.0000000000000000000000000000000000000000000000000005762 197.0
HFD2_k127_3824168_5 Belongs to the heme-copper respiratory oxidase family - - - 0.0000000000000000000001476 111.0
HFD2_k127_3824168_6 Lipid A 3-O-deacylase (PagL) - - - 0.00000000000001195 86.0
HFD2_k127_3824168_7 - - - - 0.00000000000123 78.0
HFD2_k127_3824168_8 denitrification pathway K02569,K15876 - - 0.0000000000249 72.0
HFD2_k127_3824168_9 Putative methyltransferase - - - 0.000006388 60.0
HFD2_k127_3832824_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 3.699e-257 805.0
HFD2_k127_3832824_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 628.0
HFD2_k127_3832824_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 418.0
HFD2_k127_3832824_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 386.0
HFD2_k127_3832824_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 301.0
HFD2_k127_3832824_5 COG1136 ABC-type antimicrobial peptide transport system, ATPase component K02003,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005597 294.0
HFD2_k127_3832824_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000006612 76.0
HFD2_k127_3839794_0 Linear gramicidin synthase subunit - - - 0.0 1750.0
HFD2_k127_3844057_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009039 288.0
HFD2_k127_3844057_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000757 126.0
HFD2_k127_3844057_2 Protein kinase domain K12132 - 2.7.11.1 0.00000002866 59.0
HFD2_k127_3862711_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000007574 270.0
HFD2_k127_3862711_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000008989 184.0
HFD2_k127_3862711_2 repeat-containing protein - - - 0.000000000000000000000000000000000000000000007746 185.0
HFD2_k127_3865739_0 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000000000006687 156.0
HFD2_k127_3865739_1 ig-like, plexins, transcription factors - - - 0.000009259 59.0
HFD2_k127_3865739_2 Tetratricopeptide repeat - - - 0.00007169 53.0
HFD2_k127_389169_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 550.0
HFD2_k127_389169_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 434.0
HFD2_k127_389169_2 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000002421 128.0
HFD2_k127_389169_3 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.000000000000001119 91.0
HFD2_k127_389169_4 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000002461 63.0
HFD2_k127_389169_5 smart pdz dhr glgf K04771,K08372 - 3.4.21.107 0.0000002278 61.0
HFD2_k127_3893_0 Tricorn protease homolog K08676 - - 2.148e-204 677.0
HFD2_k127_3893_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000952 467.0
HFD2_k127_3893_10 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.00000004533 55.0
HFD2_k127_3893_11 Inner membrane component of T3SS, cytoplasmic domain - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170 - 0.0000001032 63.0
HFD2_k127_3893_12 CAAX protease self-immunity K07052,K09696 - - 0.0002397 52.0
HFD2_k127_3893_2 fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 387.0
HFD2_k127_3893_3 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 357.0
HFD2_k127_3893_4 Uncharacterised conserved protein (DUF2156) K07027,K14205 - 2.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 347.0
HFD2_k127_3893_5 - K12065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 303.0
HFD2_k127_3893_6 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001443 280.0
HFD2_k127_3893_7 PFAM virulence factor family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001614 289.0
HFD2_k127_3893_8 - - - - 0.0000000000000000000000000000000000000000000000000008113 194.0
HFD2_k127_3893_9 Bacterial virulence protein (VirJ) - - - 0.000000000001064 78.0
HFD2_k127_3914809_0 Berberine and berberine like - - - 4.574e-238 748.0
HFD2_k127_3914809_1 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 499.0
HFD2_k127_3914809_2 PhoPQ-activated pathogenicity-related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 443.0
HFD2_k127_3914809_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 445.0
HFD2_k127_3914809_4 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008501 378.0
HFD2_k127_3914809_5 VIT family - - - 0.000000000000000000000000000000000000000000000001755 182.0
HFD2_k127_3914809_7 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000001789 52.0
HFD2_k127_3936895_0 response to heat K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1077.0
HFD2_k127_3936895_1 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 339.0
HFD2_k127_3936895_10 Phosphoserine phosphatase - - - 0.000000004619 68.0
HFD2_k127_3936895_11 alpha beta K06889 - - 0.000000707 55.0
HFD2_k127_3936895_2 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001035 262.0
HFD2_k127_3936895_3 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007518 265.0
HFD2_k127_3936895_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000004419 205.0
HFD2_k127_3936895_5 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774,K22110 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659 - 0.000000000000000000000000000000000000000000000004492 199.0
HFD2_k127_3936895_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000002226 149.0
HFD2_k127_3936895_7 PFAM Integral membrane protein DUF92 - GO:0005575,GO:0016020 - 0.00000000000000000000000000000000000008022 158.0
HFD2_k127_3936895_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000002683 102.0
HFD2_k127_3936895_9 UbiA prenyltransferase family K17105 - 2.5.1.42 0.0000000000006051 83.0
HFD2_k127_394042_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 432.0
HFD2_k127_394042_1 Beta-lactamase - - - 0.0000000000000000000000000006562 119.0
HFD2_k127_3948924_0 NAD dependent epimerase/dehydratase family K05281 - 1.3.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006832 335.0
HFD2_k127_3948924_1 Peptidase M36 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001487 268.0
HFD2_k127_3967321_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 8.611e-208 676.0
HFD2_k127_3967321_1 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 9.049e-201 635.0
HFD2_k127_3967321_10 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008548 247.0
HFD2_k127_3967321_11 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000839 260.0
HFD2_k127_3967321_12 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K20452 - 4.2.1.33,4.2.1.35,4.2.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000422 257.0
HFD2_k127_3967321_13 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000572 230.0
HFD2_k127_3967321_14 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000001818 236.0
HFD2_k127_3967321_15 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000005167 197.0
HFD2_k127_3967321_16 Oxygenase, catalysing oxidative methylation of damaged DNA K09990 - - 0.000000000000000000000000000000000000000000000000487 183.0
HFD2_k127_3967321_17 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000004537 166.0
HFD2_k127_3967321_18 methylated-DNA- protein -cysteine S-methyltransferase K00567 - 2.1.1.63 0.00000000000000000000000000000001283 143.0
HFD2_k127_3967321_19 Oxygenase, catalysing oxidative methylation of damaged DNA K09990 - - 0.00000000000000000000000000001577 119.0
HFD2_k127_3967321_2 Belongs to the aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 544.0
HFD2_k127_3967321_20 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000000000003936 111.0
HFD2_k127_3967321_21 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000008941 95.0
HFD2_k127_3967321_22 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000008461 70.0
HFD2_k127_3967321_23 Belongs to the peptidase S1C family - - - 0.000000001144 68.0
HFD2_k127_3967321_24 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000005326 65.0
HFD2_k127_3967321_25 Sigma factor PP2C-like phosphatases - - - 0.0001822 52.0
HFD2_k127_3967321_3 cystathionine gamma-synthase activity K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000975 536.0
HFD2_k127_3967321_4 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 393.0
HFD2_k127_3967321_5 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 360.0
HFD2_k127_3967321_6 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 299.0
HFD2_k127_3967321_7 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002257 282.0
HFD2_k127_3967321_8 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007007 267.0
HFD2_k127_3967321_9 Pfam Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001529 263.0
HFD2_k127_398668_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 382.0
HFD2_k127_398668_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 324.0
HFD2_k127_398668_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000003894 200.0
HFD2_k127_398668_3 Telomere recombination K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000002659 178.0
HFD2_k127_398668_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000000000000000003691 174.0
HFD2_k127_398668_5 Putative diguanylate phosphodiesterase - - - 0.0002274 44.0
HFD2_k127_4003379_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 581.0
HFD2_k127_4003379_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 497.0
HFD2_k127_4003379_10 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000002707 140.0
HFD2_k127_4003379_11 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000007825 130.0
HFD2_k127_4003379_12 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.00000000000000000003317 92.0
HFD2_k127_4003379_13 - - - - 0.000000000000004009 89.0
HFD2_k127_4003379_14 Tetratricopeptide repeat K07114 - - 0.000000000003368 77.0
HFD2_k127_4003379_2 ATPase associated with various cellular K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 466.0
HFD2_k127_4003379_3 von Willebrand factor (vWF) type A domain K07114,K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 358.0
HFD2_k127_4003379_4 Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 359.0
HFD2_k127_4003379_5 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001745 291.0
HFD2_k127_4003379_6 Oxygen tolerance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002429 279.0
HFD2_k127_4003379_7 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008728 263.0
HFD2_k127_4003379_8 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000003056 205.0
HFD2_k127_4003379_9 Sulfatase - - - 0.0000000000000000000000000000000000000000000000005197 191.0
HFD2_k127_4014829_0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000003108 256.0
HFD2_k127_4014829_1 Arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000002014 170.0
HFD2_k127_4014829_2 Redoxin - - - 0.0000000000000000000000000000000000605 137.0
HFD2_k127_4014829_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000001882 134.0
HFD2_k127_4016215_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000001528 198.0
HFD2_k127_4016215_1 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000006148 119.0
HFD2_k127_4046920_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000004996 160.0
HFD2_k127_4046920_1 Thioredoxin-like - - - 0.0000000000000000000002864 110.0
HFD2_k127_4046920_2 Tetratricopeptide repeat - - - 0.00000000004804 68.0
HFD2_k127_4046920_3 Heavy-metal-associated domain - - - 0.0001088 51.0
HFD2_k127_404927_0 PFAM ABC transporter K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 339.0
HFD2_k127_404927_1 transport, permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 319.0
HFD2_k127_404927_2 Transport permease protein K01992 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015562,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0033554,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000008824 252.0
HFD2_k127_404927_3 Outer membrane efflux protein - - - 0.00000000000000000000000000000001639 145.0
HFD2_k127_404927_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000001053 93.0
HFD2_k127_4058409_0 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00001418 50.0
HFD2_k127_4090364_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000005073 274.0
HFD2_k127_4104211_0 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 360.0
HFD2_k127_4104211_1 COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000003271 247.0
HFD2_k127_4123588_0 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000002418 250.0
HFD2_k127_4123588_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000003144 175.0
HFD2_k127_4123588_2 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.000000000000000000000001268 106.0
HFD2_k127_4142461_0 Concanavalin A-like lectin/glucanases superfamily - - - 0.0000000000000001752 85.0
HFD2_k127_4142461_1 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000001961 88.0
HFD2_k127_4142461_2 - - - - 0.000000002076 58.0
HFD2_k127_4171155_0 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000467 252.0
HFD2_k127_4171155_1 Belongs to the peptidase S1C family K04691,K04771,K04772 - 3.4.21.107 0.0000000000000000000000002973 121.0
HFD2_k127_4171155_3 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000004851 89.0
HFD2_k127_4171155_5 Tetratricopeptide repeat - - - 0.00000006021 64.0
HFD2_k127_4176354_0 Sortilin, neurotensin receptor 3, - - - 0.0 1113.0
HFD2_k127_4176354_1 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 344.0
HFD2_k127_4176354_2 Permease family K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008781 342.0
HFD2_k127_4253321_0 Belongs to the RtcB family K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 3.343e-209 660.0
HFD2_k127_4253321_1 Phosphate acyltransferases K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 460.0
HFD2_k127_4253321_2 Cysteine dioxygenase type I - - - 0.0000000000000000000000000000000000000000000000002481 201.0
HFD2_k127_430592_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 455.0
HFD2_k127_430592_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 359.0
HFD2_k127_430592_2 ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001921 263.0
HFD2_k127_430592_3 PDZ DHR GLGF domain protein - - - 0.00000000000000000000000000000000000000001139 169.0
HFD2_k127_430592_4 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000001167 149.0
HFD2_k127_430592_5 - - - - 0.00000000000000000000000000001849 132.0
HFD2_k127_433107_0 6-phosphogluconolactonase activity - - - 0.0000000000000000000000000000002082 145.0
HFD2_k127_4359171_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 443.0
HFD2_k127_4359171_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000008642 209.0
HFD2_k127_4366592_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 378.0
HFD2_k127_4366592_1 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000009451 226.0
HFD2_k127_4366592_2 Rhomboid family - - - 0.0000000000000000000000000000000000000000000003538 176.0
HFD2_k127_4366592_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000705 138.0
HFD2_k127_4389518_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 484.0
HFD2_k127_4389518_1 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000001095 259.0
HFD2_k127_4389518_2 Hfq protein - - - 0.0000000000000000000000000000002579 129.0
HFD2_k127_4389518_3 PFAM inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000001458 104.0
HFD2_k127_4389518_4 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.00000001586 66.0
HFD2_k127_4389518_5 peptidylprolyl isomerase K03769 - 5.2.1.8 0.0000006553 61.0
HFD2_k127_4399839_0 Bacterial type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007801 286.0
HFD2_k127_4399839_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648,K18003 - 2.3.1.180,2.3.1.262 0.000000000000000000000000000000000000000000000000000000000001471 215.0
HFD2_k127_4406426_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.491e-229 720.0
HFD2_k127_4406426_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.652e-228 715.0
HFD2_k127_4406426_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001373 284.0
HFD2_k127_4406426_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000003044 132.0
HFD2_k127_4406426_4 Bacterial PH domain K08981 - - 0.000000000000000000000000007299 116.0
HFD2_k127_4406426_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000007389 97.0
HFD2_k127_4410128_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 437.0
HFD2_k127_4410128_1 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 395.0
HFD2_k127_4410128_2 TIGRFAM cysteine desulfurase family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 331.0
HFD2_k127_4410128_3 Thrombospondin type 3 repeat - - - 0.0000000000000000000000000000000000000000000000000000000001453 230.0
HFD2_k127_4410128_4 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.000000000000000000000000000000006715 138.0
HFD2_k127_4410128_5 Belongs to the ompA family K03286 - - 0.000000000000000000009485 106.0
HFD2_k127_4410128_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.000000000000001891 83.0
HFD2_k127_4410128_7 Metallo-peptidase family M12B Reprolysin-like - - - 0.00000000000005643 87.0
HFD2_k127_4410128_8 Domain of unknown function (DUF4153) - - - 0.00000007531 53.0
HFD2_k127_4410128_9 C-terminal domain of CHU protein family - - - 0.000002256 61.0
HFD2_k127_4413643_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001294 290.0
HFD2_k127_4413643_1 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001862 266.0
HFD2_k127_4413643_2 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000005852 263.0
HFD2_k127_4413643_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000002595 184.0
HFD2_k127_4413643_4 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000007332 173.0
HFD2_k127_4413643_5 domain, Protein - - - 0.00000000000000000000000000000000000000000000009407 190.0
HFD2_k127_4413643_6 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000198 128.0
HFD2_k127_4413643_7 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000002395 109.0
HFD2_k127_4413643_8 PASTA K12132 - 2.7.11.1 0.00000000000000000005153 100.0
HFD2_k127_4421236_0 Uncharacterized protein family (UPF0051) K09014 - - 2.335e-263 826.0
HFD2_k127_4421236_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005774 576.0
HFD2_k127_4421236_10 FeS assembly ATPase SufC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 381.0
HFD2_k127_4421236_11 Ring hydroxylating alpha subunit (catalytic domain) K00479,K00499 - 1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 368.0
HFD2_k127_4421236_12 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002886 289.0
HFD2_k127_4421236_13 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000001067 198.0
HFD2_k127_4421236_14 hydrolase of the alpha beta K07018 - - 0.0000000000000000000000000000000000000000000000364 177.0
HFD2_k127_4421236_15 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000002106 167.0
HFD2_k127_4421236_16 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000002531 183.0
HFD2_k127_4421236_17 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000001336 156.0
HFD2_k127_4421236_18 2 iron, 2 sulfur cluster binding - - - 0.0000000000000000000000000000000000003731 145.0
HFD2_k127_4421236_19 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000005194 150.0
HFD2_k127_4421236_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 514.0
HFD2_k127_4421236_20 Pfam:DUF59 K02612 - - 0.00000000000000000000000000000001233 138.0
HFD2_k127_4421236_21 PFAM Nickel transport complex, NikM subunit, transmembrane - - - 0.00000000000000000000003035 110.0
HFD2_k127_4421236_22 sulfur oxidation cytochrome SoxX K17223 - - 0.000000338 58.0
HFD2_k127_4421236_3 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009368 439.0
HFD2_k127_4421236_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 429.0
HFD2_k127_4421236_5 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 421.0
HFD2_k127_4421236_6 alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005634 422.0
HFD2_k127_4421236_7 FeS assembly protein SufD K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 404.0
HFD2_k127_4421236_8 protoporphyrinogen oxidase activity K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 415.0
HFD2_k127_4421236_9 PFAM Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 386.0
HFD2_k127_4423109_0 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 513.0
HFD2_k127_4423109_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002528 250.0
HFD2_k127_4423109_2 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000003374 208.0
HFD2_k127_4423109_3 Calcium/calmodulin dependent protein kinase II association domain - - - 0.000000007755 65.0
HFD2_k127_4469802_0 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007299 403.0
HFD2_k127_4469802_1 dehydratase K01754 - 4.3.1.19 0.00000000000000000000000009068 111.0
HFD2_k127_4469802_2 endonuclease activity K07451 - - 0.00000001042 58.0
HFD2_k127_4469895_0 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 1.168e-231 727.0
HFD2_k127_4469895_1 acetyl-CoA carboxylase biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 422.0
HFD2_k127_4469895_2 PFAM pyruvate carboxyltransferase K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 329.0
HFD2_k127_4469895_3 Enoyl-CoA hydratase/isomerase K13766,K13779 - 4.2.1.18,4.2.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000001305 259.0
HFD2_k127_4469895_4 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000007623 213.0
HFD2_k127_4469895_5 carboxylase K01968 - 6.4.1.4 0.00000001176 68.0
HFD2_k127_4469895_6 endonuclease activity K07451 - - 0.00000001433 58.0
HFD2_k127_4488620_0 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000338 265.0
HFD2_k127_4488620_1 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.000000000000000000000000000006999 135.0
HFD2_k127_4488620_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000001321 65.0
HFD2_k127_4498009_0 TIGRFAM glycerol-3-phosphate dehydrogenase, anaerobic, C subunit K00113 - 1.1.5.3 2.199e-208 681.0
HFD2_k127_4498009_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 9.498e-200 645.0
HFD2_k127_4498009_10 Domain of Unknown Function (DUF349) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 332.0
HFD2_k127_4498009_11 GHMP kinases N terminal domain K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000002437 233.0
HFD2_k127_4498009_12 (Rhomboid) family - - - 0.000000000000000000000000000000000000000000000000000000000002146 216.0
HFD2_k127_4498009_13 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000009541 221.0
HFD2_k127_4498009_14 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000002462 213.0
HFD2_k127_4498009_15 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000004291 205.0
HFD2_k127_4498009_16 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000000001975 177.0
HFD2_k127_4498009_17 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000000602 180.0
HFD2_k127_4498009_18 dephospho-CoA kinase activity - - - 0.0000000000000000000000000000000007312 138.0
HFD2_k127_4498009_19 Domain of unknown function (DUF1949) - - - 0.0000000000000000000000000000009832 128.0
HFD2_k127_4498009_2 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 620.0
HFD2_k127_4498009_20 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000002437 108.0
HFD2_k127_4498009_21 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000002662 111.0
HFD2_k127_4498009_22 - - - - 0.0000000000000000000002446 110.0
HFD2_k127_4498009_24 Polymer-forming cytoskeletal - - - 0.0000000000004274 76.0
HFD2_k127_4498009_25 Tetratricopeptide repeats - - - 0.000000763 55.0
HFD2_k127_4498009_26 COG0457 FOG TPR repeat - - - 0.000003998 60.0
HFD2_k127_4498009_27 - - - - 0.000013 57.0
HFD2_k127_4498009_3 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 506.0
HFD2_k127_4498009_4 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 409.0
HFD2_k127_4498009_5 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009317 395.0
HFD2_k127_4498009_6 aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 391.0
HFD2_k127_4498009_7 ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 365.0
HFD2_k127_4498009_8 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 362.0
HFD2_k127_4498009_9 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 344.0
HFD2_k127_4514340_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K03737 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0016625,GO:0016903,GO:0043873,GO:0050896,GO:0055114 1.2.7.1 0.0 1509.0
HFD2_k127_4514340_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 395.0
HFD2_k127_4515274_0 cellulose binding - - - 3.382e-291 915.0
HFD2_k127_4515274_1 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 490.0
HFD2_k127_4515274_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 326.0
HFD2_k127_4515274_3 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 323.0
HFD2_k127_4515274_4 Arsenical pump membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007314 286.0
HFD2_k127_4515274_5 FecCD transport family K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000005019 247.0
HFD2_k127_4515274_6 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000001819 235.0
HFD2_k127_4515274_7 Abc transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000416 216.0
HFD2_k127_4515274_8 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000008396 170.0
HFD2_k127_4515274_9 Putative modulator of DNA gyrase K03592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.00000002109 67.0
HFD2_k127_4534167_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1305.0
HFD2_k127_4534167_1 Aromatic amino acid lyase K01745 - 4.3.1.3 1.613e-251 807.0
HFD2_k127_4534167_10 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 380.0
HFD2_k127_4534167_11 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 374.0
HFD2_k127_4534167_12 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008872 312.0
HFD2_k127_4534167_13 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001972 244.0
HFD2_k127_4534167_14 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000006121 259.0
HFD2_k127_4534167_15 PFAM M42 glutamyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000002038 257.0
HFD2_k127_4534167_16 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000001937 227.0
HFD2_k127_4534167_17 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000008499 178.0
HFD2_k127_4534167_18 PFAM M42 glutamyl aminopeptidase - - - 0.0000000000000000000000000000000003714 145.0
HFD2_k127_4534167_19 Transcriptional regulator - - - 0.00000000000000002022 91.0
HFD2_k127_4534167_2 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 637.0
HFD2_k127_4534167_20 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.00000000004446 75.0
HFD2_k127_4534167_21 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.00000003692 57.0
HFD2_k127_4534167_22 COG0457 FOG TPR repeat - - - 0.00000006744 66.0
HFD2_k127_4534167_3 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 558.0
HFD2_k127_4534167_4 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 526.0
HFD2_k127_4534167_5 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 430.0
HFD2_k127_4534167_6 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 420.0
HFD2_k127_4534167_7 SpoIVB peptidase S55 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007299 387.0
HFD2_k127_4534167_8 Bacterial regulatory protein, Fis family K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008872 400.0
HFD2_k127_4534167_9 Amidohydrolase family K01465,K06015 - 3.5.1.81,3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 372.0
HFD2_k127_4537829_0 ATPase activity K02045 - 3.6.3.25 2.023e-211 678.0
HFD2_k127_4537829_1 COG1613 ABC-type sulfate transport system, periplasmic component K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005466 501.0
HFD2_k127_4537829_2 sulfate ABC transporter K02047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 387.0
HFD2_k127_4537829_3 COG0555 ABC-type sulfate transport system, permease component K02046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000715 384.0
HFD2_k127_4537829_4 PFAM Phosphate-selective porin O K07221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006874 335.0
HFD2_k127_4537829_5 His Kinase A (phosphoacceptor) domain K07641,K10819 - 2.7.13.3 0.000000000000004295 84.0
HFD2_k127_457054_0 choline dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 542.0
HFD2_k127_457054_1 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002614 275.0
HFD2_k127_457054_2 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000002561 166.0
HFD2_k127_457054_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.00000000000000172 90.0
HFD2_k127_4577540_0 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 550.0
HFD2_k127_4577540_1 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 329.0
HFD2_k127_4577540_2 Sortase (surface protein transpeptidase) K07284 - 3.4.22.70 0.000007465 55.0
HFD2_k127_4577540_3 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.0005045 47.0
HFD2_k127_4584069_0 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 496.0
HFD2_k127_4606731_0 PFAM magnesium chelatase ChlI subunit K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 476.0
HFD2_k127_4606731_1 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 436.0
HFD2_k127_4606731_10 Belongs to the HAD-like hydrolase superfamily K02566 - - 0.000000000000000000000000000000000000000000000000000003407 201.0
HFD2_k127_4606731_11 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000001321 114.0
HFD2_k127_4606731_12 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000004255 105.0
HFD2_k127_4606731_13 Tetratricopeptide repeat - - - 0.0000000000000000002545 100.0
HFD2_k127_4606731_2 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029,K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 423.0
HFD2_k127_4606731_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 369.0
HFD2_k127_4606731_4 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 330.0
HFD2_k127_4606731_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 319.0
HFD2_k127_4606731_6 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 290.0
HFD2_k127_4606731_7 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000007194 264.0
HFD2_k127_4606731_8 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000003568 235.0
HFD2_k127_4606731_9 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000002705 220.0
HFD2_k127_4616380_0 SpoVR like protein K06415 - - 2.655e-196 641.0
HFD2_k127_4616380_1 Belongs to the UPF0229 family K09786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008968 524.0
HFD2_k127_4616380_2 CobQ CobB MinD ParA nucleotide binding K04562 - - 0.000000000000000000000000000000009182 146.0
HFD2_k127_4616380_3 PrkA AAA domain K07180 - - 0.000000000002186 66.0
HFD2_k127_4651959_0 YCII-related domain - - - 0.000000000000000000000000000000000000000000003215 173.0
HFD2_k127_4651959_1 TM2 domain - - - 0.0000004765 59.0
HFD2_k127_4654726_0 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000007562 228.0
HFD2_k127_4654726_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000002316 222.0
HFD2_k127_4654726_2 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000001349 203.0
HFD2_k127_4654726_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000003045 192.0
HFD2_k127_4654726_4 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000006264 116.0
HFD2_k127_4654726_5 DNA-directed 5'-3' RNA polymerase activity K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0001658 50.0
HFD2_k127_4663289_0 Belongs to the peptidase S8 family K17734 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008904 296.0
HFD2_k127_4663289_1 PFAM Thioredoxin K05838 - - 0.000002964 61.0
HFD2_k127_4695772_0 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 465.0
HFD2_k127_4695772_1 Belongs to the PAPS reductase family. CysH subfamily K00366,K00390,K00860 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.7.7.1,1.8.4.10,1.8.4.8,2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008764 333.0
HFD2_k127_4706038_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 5.662e-216 680.0
HFD2_k127_4706038_1 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 423.0
HFD2_k127_4706038_2 CAAX protease self-immunity K07052,K09696 - - 0.0000000000000000008784 93.0
HFD2_k127_4709256_0 DegT/DnrJ/EryC1/StrS aminotransferase family K04127 - 5.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 420.0
HFD2_k127_4709256_1 Di-haem oxidoreductase, putative peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000102 262.0
HFD2_k127_4709256_2 Patatin-like phospholipase - - - 0.0000000000002137 77.0
HFD2_k127_4709256_3 Transcriptional regulator PadR-like family - - - 0.0000000000006303 70.0
HFD2_k127_4716453_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 6.074e-292 918.0
HFD2_k127_4716453_1 aconitate hydratase K01681 - 4.2.1.3 9.849e-269 839.0
HFD2_k127_4716453_10 PFAM Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000001621 218.0
HFD2_k127_4716453_11 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000003673 217.0
HFD2_k127_4716453_12 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000005136 130.0
HFD2_k127_4716453_13 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000007102 125.0
HFD2_k127_4716453_14 Cold shock K03704 - - 0.00000000000000000000000005108 111.0
HFD2_k127_4716453_2 Dipeptidyl peptidase IV (DPP IV) K01278 - 3.4.14.5 8.328e-225 721.0
HFD2_k127_4716453_3 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 617.0
HFD2_k127_4716453_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 390.0
HFD2_k127_4716453_5 AAA ATPase K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 370.0
HFD2_k127_4716453_6 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 325.0
HFD2_k127_4716453_7 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 299.0
HFD2_k127_4716453_8 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004689 276.0
HFD2_k127_4716453_9 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006492 283.0
HFD2_k127_4739233_0 SMART Tetratricopeptide domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000002754 239.0
HFD2_k127_4794362_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 539.0
HFD2_k127_4794362_1 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000008252 165.0
HFD2_k127_4794362_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.00000000000000000000000001551 110.0
HFD2_k127_4817108_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 3.799e-223 717.0
HFD2_k127_4817108_1 PFAM Acyl-CoA dehydrogenase K00248,K22430 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 1.3.1.108,1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009528 447.0
HFD2_k127_4817108_10 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000103 199.0
HFD2_k127_4817108_11 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000132 172.0
HFD2_k127_4817108_12 PFAM regulatory protein, MerR K13640 - - 0.00000000000000000000000000000001406 135.0
HFD2_k127_4817108_13 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000857 79.0
HFD2_k127_4817108_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 415.0
HFD2_k127_4817108_3 RNA polymerase sigma-54 factor K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 390.0
HFD2_k127_4817108_4 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 353.0
HFD2_k127_4817108_5 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 315.0
HFD2_k127_4817108_6 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002368 280.0
HFD2_k127_4817108_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000245 247.0
HFD2_k127_4817108_8 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000006871 244.0
HFD2_k127_4817108_9 IstB-like ATP binding protein K02315 - - 0.00000000000000000000000000000000000000000000000000000001446 206.0
HFD2_k127_4828243_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 544.0
HFD2_k127_4828243_1 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000002233 213.0
HFD2_k127_4828243_2 arylsulfatase A - - - 0.0000000000000000000000000009721 130.0
HFD2_k127_4828243_3 Serine aminopeptidase, S33 - - - 0.0000000000003319 80.0
HFD2_k127_4852951_0 PFAM GlcNAc-PI de-N-acetylase - - - 2.18e-275 884.0
HFD2_k127_4852951_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 4.261e-221 701.0
HFD2_k127_4852951_2 Zn-dependent protease with chaperone function K03799,K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 424.0
HFD2_k127_4852951_3 PFAM glycosyl transferase group 1 K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 419.0
HFD2_k127_4852951_4 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 306.0
HFD2_k127_4852951_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003826 294.0
HFD2_k127_4852951_6 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000002533 222.0
HFD2_k127_4852951_7 Protein of unknown function (DUF2911) - - - 0.00000000000000000000000000000000000000000000000000000000000544 222.0
HFD2_k127_4852951_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000002683 71.0
HFD2_k127_4852951_9 Calcium/calmodulin dependent protein kinase II association domain - - - 0.00002196 55.0
HFD2_k127_4867575_0 peptidyl-tyrosine sulfation - - - 6.046e-264 834.0
HFD2_k127_4867575_1 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000007044 123.0
HFD2_k127_4867575_2 Cytochrome c554 and c-prime - - - 0.00000000009089 74.0
HFD2_k127_4874411_0 Dehydrogenase E1 component K11381 - 1.2.4.4 2.529e-270 869.0
HFD2_k127_4874411_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 399.0
HFD2_k127_4874411_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006961 282.0
HFD2_k127_4874411_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000001294 204.0
HFD2_k127_4874411_4 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000001201 203.0
HFD2_k127_4874411_5 PFAM dehydrogenase, E1 component - - - 0.000000000000000000000000000000000000000000007812 184.0
HFD2_k127_4874411_6 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000005522 95.0
HFD2_k127_4874411_7 - - - - 0.00000000000001044 83.0
HFD2_k127_4886767_0 FAD binding domain K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 444.0
HFD2_k127_4886767_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000001254 149.0
HFD2_k127_4886767_2 heat shock protein binding K05516,K05801 - - 0.0000000000000000000000001372 123.0
HFD2_k127_4886767_3 Heat shock protein DnaJ domain protein - - - 0.00000000000000000001471 107.0
HFD2_k127_4907891_0 Molybdopterin oxidoreductase - - - 1.469e-226 707.0
HFD2_k127_4907891_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00371,K16965,K17048,K17051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 597.0
HFD2_k127_4907891_2 Fe-S oxidoreductases K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 361.0
HFD2_k127_4907891_3 Domain of unknown function (DUF1858) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 364.0
HFD2_k127_4907891_4 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.0000000000000000000000000000001557 133.0
HFD2_k127_4907891_5 - - - - 0.0000000000000000000001008 112.0
HFD2_k127_4907891_6 Nitrate reductase delta subunit - - - 0.000000000000000000003862 106.0
HFD2_k127_4932672_0 WD40-like Beta Propeller Repeat - - - 2.432e-257 817.0
HFD2_k127_4932672_1 Creatinase/Prolidase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 429.0
HFD2_k127_4932672_2 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000002529 76.0
HFD2_k127_495012_0 Cytochrome c - - - 8.02e-197 621.0
HFD2_k127_495012_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009919 534.0
HFD2_k127_495012_2 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 0.00000000000000000005733 104.0
HFD2_k127_4954603_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 509.0
HFD2_k127_4954603_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 496.0
HFD2_k127_4954603_2 formate dehydrogenase (NAD+) activity K00336,K18006 - 1.12.1.2,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 437.0
HFD2_k127_4954603_3 quinone binding K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 392.0
HFD2_k127_4954603_4 NADH-quinone oxidoreductase K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000002386 174.0
HFD2_k127_4954603_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000001725 115.0
HFD2_k127_4954603_6 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000003567 105.0
HFD2_k127_4954603_7 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 0.0000005936 57.0
HFD2_k127_4954603_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00332 - 1.6.5.3 0.000006783 49.0
HFD2_k127_5003213_0 ABC transporter K06158 - - 2.442e-198 638.0
HFD2_k127_5003213_1 response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 319.0
HFD2_k127_5032107_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 2.035e-259 809.0
HFD2_k127_5032107_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00122,K00335 - 1.17.1.9,1.6.5.3 4.38e-240 757.0
HFD2_k127_5032107_2 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 572.0
HFD2_k127_5032107_3 2Fe-2S iron-sulfur cluster binding domain K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 418.0
HFD2_k127_5032107_4 Molybdopterin oxidoreductase - - - 0.000000000000000000000000000008882 124.0
HFD2_k127_5032107_5 Domain of unknown function (DUF4115) K15539 - - 0.000000000000000001048 89.0
HFD2_k127_5032107_6 - - - - 0.0000000000000001807 91.0
HFD2_k127_5032107_7 - - - - 0.000007749 58.0
HFD2_k127_5086509_0 GTP-binding protein TypA K06207 - - 1.44e-229 727.0
HFD2_k127_5086509_1 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000007683 171.0
HFD2_k127_5086509_2 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000001169 124.0
HFD2_k127_5086509_3 methyltransferase - - - 0.0000002688 63.0
HFD2_k127_5101515_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1032.0
HFD2_k127_5101515_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 5.151e-298 934.0
HFD2_k127_5101515_2 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 9.653e-249 780.0
HFD2_k127_5101515_3 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 517.0
HFD2_k127_5101515_4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 462.0
HFD2_k127_5101515_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 321.0
HFD2_k127_5122866_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000003518 235.0
HFD2_k127_5122866_1 5'-nucleotidase - - - 0.00000000000000000000000000000000000000447 161.0
HFD2_k127_5122866_2 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000007259 149.0
HFD2_k127_5135023_0 acyl-coa dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 447.0
HFD2_k127_5135023_1 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00146,K10217 - 1.2.1.3,1.2.1.32,1.2.1.39,1.2.1.8,1.2.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 424.0
HFD2_k127_5165562_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.803e-210 661.0
HFD2_k127_5165562_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 531.0
HFD2_k127_5165562_10 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0005502 47.0
HFD2_k127_5165562_2 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 388.0
HFD2_k127_5165562_3 TIGR00266 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000072 264.0
HFD2_k127_5165562_4 copper resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000001268 242.0
HFD2_k127_5165562_5 pseudouridine synthase activity K06180 - 5.4.99.23 0.000000000000000000000000000000000000000002644 164.0
HFD2_k127_5165562_6 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000008796 154.0
HFD2_k127_5165562_7 COG0694 Thioredoxin-like proteins and domains - - - 0.00000000000000000000000000001197 120.0
HFD2_k127_5165562_8 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00001288 48.0
HFD2_k127_5165562_9 peptidyl-prolyl cis-trans isomerase activity K01802,K03769,K03770 - 5.2.1.8 0.0004809 47.0
HFD2_k127_5195795_0 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 575.0
HFD2_k127_5195795_1 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 482.0
HFD2_k127_5195795_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 463.0
HFD2_k127_5195795_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 367.0
HFD2_k127_5195795_4 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 340.0
HFD2_k127_5195795_5 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000002818 234.0
HFD2_k127_5195795_6 peptidase - - - 0.00000000000000000000000000000002347 138.0
HFD2_k127_5195795_7 Protein of unknown function (DUF1579) - - - 0.000000000000000000000000000004265 127.0
HFD2_k127_519717_0 transport system involved in gliding motility, auxiliary K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 368.0
HFD2_k127_519717_1 ATPase activity K01990,K09697 - 3.6.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 321.0
HFD2_k127_519717_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000004678 223.0
HFD2_k127_519717_3 Domain of unknown function (DUF4340) - - - 0.0000000000000000000000000125 127.0
HFD2_k127_521658_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1144.0
HFD2_k127_521658_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 9.423e-198 647.0
HFD2_k127_521658_2 TIGRFAM leucyl-tRNA synthetase K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 527.0
HFD2_k127_521658_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 439.0
HFD2_k127_521658_4 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.00000000000000000000000000000003436 132.0
HFD2_k127_521658_5 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000005934 120.0
HFD2_k127_5228659_0 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000001341 244.0
HFD2_k127_5228659_1 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000001029 156.0
HFD2_k127_5228659_2 Peptidase s1 and s6 chymotrypsin hap - - - 0.0002709 53.0
HFD2_k127_523102_0 IgA Peptidase M64 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 509.0
HFD2_k127_523102_1 MacB-like periplasmic core domain K02004,K05685 - - 0.000000000000000000000000000000000000000000000000000000001563 205.0
HFD2_k127_523102_2 Glutaredoxin K07390 - - 0.00000000000000000000000000000002154 128.0
HFD2_k127_523102_3 BolA-like protein - - - 0.0000000000000001179 81.0
HFD2_k127_5235741_0 Short-chain dehydrogenase reductase SDR - - - 1.527e-253 800.0
HFD2_k127_5235741_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 8.181e-203 641.0
HFD2_k127_5235741_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases - - - 0.00000000000000000000000000000000000000000000000000000000000000000003108 239.0
HFD2_k127_5280028_0 Semialdehyde dehydrogenase, NAD binding domain K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000004611 270.0
HFD2_k127_5280028_1 Regulates arginine biosynthesis genes K03402 - - 0.0000000000000000000007406 100.0
HFD2_k127_5280028_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000007276 85.0
HFD2_k127_5283528_0 AI-2E family transporter - - - 0.00000000000000000000000000000000005986 148.0
HFD2_k127_5283528_1 chlorophyll binding - - - 0.000000000000000000002511 96.0
HFD2_k127_5283528_2 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811,K09812 GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0040011,GO:0042173,GO:0042221,GO:0043207,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0071976,GO:0090529,GO:1902531 - 0.00000000003892 69.0
HFD2_k127_5301571_0 4Fe-4S single cluster domain K06937 - - 9.814e-248 781.0
HFD2_k127_5301571_1 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 482.0
HFD2_k127_5301571_2 PAS domain K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 479.0
HFD2_k127_5301571_3 glutamate--cysteine ligase K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 370.0
HFD2_k127_5301571_4 PFAM Formiminotransferase domain K00603 - 2.1.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 360.0
HFD2_k127_5301571_5 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000001372 274.0
HFD2_k127_5301571_6 transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000003093 122.0
HFD2_k127_5301571_7 Domain of unknown function (DUF4390) - - - 0.000001122 58.0
HFD2_k127_5301571_8 Helix-turn-helix domain - - - 0.00001629 48.0
HFD2_k127_5304555_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001398 274.0
HFD2_k127_5304555_1 Protein of unknown function (DUF1328) - - - 0.00001369 49.0
HFD2_k127_5304555_2 periplasmic or secreted lipoprotein - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0032153,GO:0044462,GO:0044464,GO:0071944 - 0.00007398 52.0
HFD2_k127_5307590_0 Protein kinase domain K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000003719 241.0
HFD2_k127_5307590_1 TIGRFAM amino acid carrier protein K03310 - - 0.00000000000000000000000000000000000000002144 154.0
HFD2_k127_5307590_2 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.000000000000000000000000000000000001945 149.0
HFD2_k127_5307590_3 FHA domain - - - 0.0000000003365 73.0
HFD2_k127_5320705_0 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 323.0
HFD2_k127_5320705_1 periplasmic protein - - - 0.000000000000000000000000000000000000000000000000000007335 211.0
HFD2_k127_5320705_2 - - - - 0.000000000000001612 84.0
HFD2_k127_5320705_3 Predicted membrane protein (DUF2339) - - - 0.00000004498 66.0
HFD2_k127_5341417_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K13019 - 5.1.3.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 394.0
HFD2_k127_5341417_1 glycosyl transferase - - - 0.0002788 53.0
HFD2_k127_5345282_0 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 510.0
HFD2_k127_5345282_1 Thiamine biosynthesis protein (ThiI) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 328.0
HFD2_k127_5381745_0 Glycosyl transferase, family 2 K13500 - 2.4.1.175,2.4.1.226 0.0000000000000000000000000000000000000000000000007116 186.0
HFD2_k127_5381745_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000003192 185.0
HFD2_k127_5381745_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000001839 101.0
HFD2_k127_5381745_3 Phospholipid methyltransferase - - - 0.000000000000000000003744 100.0
HFD2_k127_5395158_0 PhoD-like phosphatase K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 551.0
HFD2_k127_5395158_1 Aldo Keto reductase K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007735 338.0
HFD2_k127_5395158_2 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001082 282.0
HFD2_k127_5395158_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000006792 97.0
HFD2_k127_5395158_4 Glycosyl transferase - - - 0.00000000000000006632 84.0
HFD2_k127_5395158_5 Uncharacterised nucleotidyltransferase - - - 0.0000000000000001086 92.0
HFD2_k127_5395158_6 - - - - 0.0000000000000001725 86.0
HFD2_k127_5395158_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000001132 58.0
HFD2_k127_5395158_8 Belongs to the ompA family K03286 - - 0.000001224 58.0
HFD2_k127_5397441_0 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 426.0
HFD2_k127_5397441_1 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001792 248.0
HFD2_k127_5397441_2 DEAD DEAH box helicase domain protein K06877 - - 0.000000000000000000000000000000000000000000704 160.0
HFD2_k127_5397441_3 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.00000000000000000000000000000000000000004018 160.0
HFD2_k127_5397441_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000007098 97.0
HFD2_k127_5432442_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 1.246e-299 977.0
HFD2_k127_5432442_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.1.1.12 2.92e-198 635.0
HFD2_k127_5432442_10 succinylglutamate desuccinylase aspartoacylase K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001078 301.0
HFD2_k127_5432442_11 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000003511 154.0
HFD2_k127_5432442_12 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.00000000000000000000000000000000004808 145.0
HFD2_k127_5432442_13 Involved in DNA repair and RecF pathway recombination K03474,K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 0.00000000000000000000000000006855 125.0
HFD2_k127_5432442_14 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000002684 97.0
HFD2_k127_5432442_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 499.0
HFD2_k127_5432442_3 PFAM glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 425.0
HFD2_k127_5432442_4 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 415.0
HFD2_k127_5432442_5 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 361.0
HFD2_k127_5432442_6 Divalent cation transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000417 365.0
HFD2_k127_5432442_7 7TM-HD extracellular K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007271 386.0
HFD2_k127_5432442_8 Belongs to the RimK family K05844,K14940 - 6.3.2.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 321.0
HFD2_k127_5432442_9 KH domain K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 312.0
HFD2_k127_5446507_0 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00135,K00138,K00146 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.39,1.2.1.79,1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 605.0
HFD2_k127_5446507_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000329 214.0
HFD2_k127_5446507_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000002126 183.0
HFD2_k127_5446507_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000005868 155.0
HFD2_k127_5446507_4 Belongs to the peptidase S1C family - - - 0.000000000000000000000000004596 128.0
HFD2_k127_5446507_5 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000006533 114.0
HFD2_k127_5447177_0 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009979 572.0
HFD2_k127_5447177_1 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00821,K05830,K09251 - 2.6.1.11,2.6.1.17,2.6.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 554.0
HFD2_k127_5447177_10 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000007718 279.0
HFD2_k127_5447177_11 PD-(D/E)XK nuclease superfamily K03657,K07465 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000908 242.0
HFD2_k127_5447177_12 deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000001313 220.0
HFD2_k127_5447177_13 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000004645 207.0
HFD2_k127_5447177_14 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000001123 184.0
HFD2_k127_5447177_15 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000004493 175.0
HFD2_k127_5447177_17 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000001386 161.0
HFD2_k127_5447177_18 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02658 - - 0.000000000000000000000000002872 127.0
HFD2_k127_5447177_19 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000004566 110.0
HFD2_k127_5447177_2 Belongs to the aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 529.0
HFD2_k127_5447177_20 Chalcone and stilbene synthases, C-terminal domain K16167,K19580 - 2.3.1.233 0.000000000000000000009023 103.0
HFD2_k127_5447177_21 Domain of unknown function (DUF4388) - - - 0.00000000000000000115 100.0
HFD2_k127_5447177_22 Peptidase M16 inactive domain K07263 - - 0.0000000001038 65.0
HFD2_k127_5447177_23 ABC-2 family transporter protein - - - 0.0000002656 64.0
HFD2_k127_5447177_24 Histidine kinase - - - 0.000002495 58.0
HFD2_k127_5447177_25 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00006585 56.0
HFD2_k127_5447177_26 Domain of unknown function (DUF4382) - - - 0.0006609 49.0
HFD2_k127_5447177_3 Aminotransferase class-III K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008231 536.0
HFD2_k127_5447177_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K09251 - 2.6.1.82 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 434.0
HFD2_k127_5447177_5 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007915 407.0
HFD2_k127_5447177_6 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007318 392.0
HFD2_k127_5447177_7 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009684 397.0
HFD2_k127_5447177_8 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 322.0
HFD2_k127_5447177_9 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001708 278.0
HFD2_k127_545635_0 metalloendopeptidase activity K01283 - 3.4.15.1 2.444e-228 714.0
HFD2_k127_545635_1 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000000000002884 114.0
HFD2_k127_545635_2 amine dehydrogenase activity - - - 0.000000000004455 80.0
HFD2_k127_545635_3 alpha-L-arabinofuranosidase - - - 0.00001299 59.0
HFD2_k127_5466160_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 1.059e-315 989.0
HFD2_k127_5466160_1 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 484.0
HFD2_k127_5466160_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005191 315.0
HFD2_k127_5466160_3 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000001039 172.0
HFD2_k127_5466160_4 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.0000000000000000000005946 101.0
HFD2_k127_5470743_0 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 321.0
HFD2_k127_5470743_1 - - - - 0.00000000000000000000000000000007367 130.0
HFD2_k127_5470743_2 oligosaccharyl transferase activity - - - 0.000000000008891 76.0
HFD2_k127_5470743_3 Peptidoglycan binding domain - - - 0.0000156 51.0
HFD2_k127_5477931_0 Beta-eliminating lyase K01667 - 4.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 574.0
HFD2_k127_5477931_1 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000687 450.0
HFD2_k127_5477931_10 - - - - 0.0000000000000000001404 98.0
HFD2_k127_5477931_11 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114 1.2.7.1 0.000000000000000002858 89.0
HFD2_k127_5477931_2 S-(hydroxymethyl)glutathione dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004173 446.0
HFD2_k127_5477931_3 benzoyl-CoA reductase K04113 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 418.0
HFD2_k127_5477931_4 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008608 363.0
HFD2_k127_5477931_5 GGDEF domain' - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 368.0
HFD2_k127_5477931_6 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008274 280.0
HFD2_k127_5477931_7 Enoyl-(Acyl carrier protein) reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.000000000000000000000000000000000000000000000000000000000001398 223.0
HFD2_k127_5477931_8 CoA-substrate-specific enzyme activase - - - 0.00000000000000000000000000000000000000000000000000000000004061 225.0
HFD2_k127_5477931_9 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000000004962 194.0
HFD2_k127_5486455_0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000008845 208.0
HFD2_k127_5486455_1 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000001994 197.0
HFD2_k127_5486455_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000006832 186.0
HFD2_k127_5486455_3 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000001241 166.0
HFD2_k127_5486455_4 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000002696 142.0
HFD2_k127_5486455_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000002248 94.0
HFD2_k127_5486455_6 Ribosomal protein L30 K02907 - - 0.000000004842 61.0
HFD2_k127_5489278_0 histidine kinase A domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 357.0
HFD2_k127_5489278_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007786 282.0
HFD2_k127_5489278_2 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001052 271.0
HFD2_k127_5489278_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000007904 243.0
HFD2_k127_5489278_4 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000003629 211.0
HFD2_k127_5495653_0 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 473.0
HFD2_k127_5495653_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005372 310.0
HFD2_k127_5495653_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000001939 274.0
HFD2_k127_5495653_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000002336 187.0
HFD2_k127_5495653_4 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 0.00000000000000000000000000000000007425 138.0
HFD2_k127_5495653_5 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000001707 106.0
HFD2_k127_5495653_6 - - - - 0.0000000000000000000001162 103.0
HFD2_k127_5495653_7 translation initiation factor activity K03699 - - 0.000000000000000000000617 108.0
HFD2_k127_5511576_0 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000003829 171.0
HFD2_k127_5511576_1 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000007564 169.0
HFD2_k127_5511576_2 Archaeal Type IV pilin, N-terminal - - - 0.000955 49.0
HFD2_k127_5511958_0 Oligoendopeptidase f - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009837 309.0
HFD2_k127_5511958_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007717 286.0
HFD2_k127_5511958_2 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000008543 251.0
HFD2_k127_5511958_3 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000001527 125.0
HFD2_k127_5511958_4 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000001101 97.0
HFD2_k127_5511958_5 PFAM Surface antigen variable number repeat K07277 - - 0.000001864 61.0
HFD2_k127_5511958_6 Belongs to the ompA family K03286 - - 0.00001136 56.0
HFD2_k127_5522622_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 580.0
HFD2_k127_5522622_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 555.0
HFD2_k127_5522622_2 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000002551 222.0
HFD2_k127_5522622_3 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000146 177.0
HFD2_k127_5522622_4 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.00000000000000000000002622 102.0
HFD2_k127_5522622_5 Zn-dependent protease with chaperone function K07387 - - 0.0000000000000000001603 100.0
HFD2_k127_5522622_6 - - - - 0.0001255 52.0
HFD2_k127_5531265_0 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 477.0
HFD2_k127_5531265_1 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 413.0
HFD2_k127_5531265_2 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000002517 196.0
HFD2_k127_5531265_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000002304 146.0
HFD2_k127_5531265_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000002584 132.0
HFD2_k127_5534259_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 - 2.2.1.2,5.3.1.9 0.0 1143.0
HFD2_k127_5534259_1 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 1.573e-216 684.0
HFD2_k127_5534259_2 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 479.0
HFD2_k127_5534259_3 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 379.0
HFD2_k127_5534259_4 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 367.0
HFD2_k127_5534259_5 metal-dependent phosphohydrolase, HD sub domain K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 378.0
HFD2_k127_5534259_6 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 356.0
HFD2_k127_5534259_7 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 314.0
HFD2_k127_5534259_8 PFAM glucosamine galactosamine-6-phosphate isomerase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000007363 206.0
HFD2_k127_5534259_9 PFAM CHAD domain containing protein - - - 0.0000000002435 71.0
HFD2_k127_5536422_0 response regulator K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 481.0
HFD2_k127_5536422_1 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000001378 150.0
HFD2_k127_5536422_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000002886 102.0
HFD2_k127_5536422_3 Histidine kinase K02482,K07709,K07710 - 2.7.13.3 0.00000000000000006976 83.0
HFD2_k127_5563263_0 DinB superfamily - - - 0.000000000000000000000000000000000000000000001235 170.0
HFD2_k127_5563263_1 - - - - 0.00000000000000000000000000000000000002247 150.0
HFD2_k127_5563263_2 - - - - 0.0005061 44.0
HFD2_k127_5573829_0 iron-nicotianamine transmembrane transporter activity - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.000000000000000000000000000000000000000000000000000000000000000000001079 245.0
HFD2_k127_5573829_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000001212 215.0
HFD2_k127_5573829_2 transglycosylase associated protein - - - 0.0000000000000005103 90.0
HFD2_k127_5573829_3 TIGRFAM TonB K03832 - - 0.000000000182 72.0
HFD2_k127_5573829_4 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000006154 56.0
HFD2_k127_5583029_0 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 391.0
HFD2_k127_5583029_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 360.0
HFD2_k127_5583029_2 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008267 361.0
HFD2_k127_5583029_3 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000003079 197.0
HFD2_k127_5629000_0 ABC transporter transmembrane region K06147 - - 9.467e-289 898.0
HFD2_k127_5629000_1 major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 490.0
HFD2_k127_5629000_2 Allophanate hydrolase subunit 2 K01457,K01941 - 3.5.1.54,6.3.4.6 0.0000000000000000000000000000000000000000000000000000000000000000002024 242.0
HFD2_k127_5629000_3 5-oxoprolinase (ATP-hydrolyzing) activity K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000003963 232.0
HFD2_k127_5629000_4 regulation of canonical Wnt signaling pathway involved in osteoblast differentiation - - - 0.000000000000000000000000000000000000000000001208 191.0
HFD2_k127_5629000_5 - - - - 0.00000000000000000000000000000000000013 149.0
HFD2_k127_5629000_6 BON domain - - - 0.000000000000000166 89.0
HFD2_k127_5629000_7 Peptidase family C25 - - - 0.000000007293 70.0
HFD2_k127_5629000_8 Thrombospondin type 3 repeat - - - 0.000000009604 70.0
HFD2_k127_5637016_0 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008089 335.0
HFD2_k127_5637016_1 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 333.0
HFD2_k127_5637016_2 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 324.0
HFD2_k127_5637016_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000002901 223.0
HFD2_k127_5637016_4 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000003037 205.0
HFD2_k127_5637016_5 Diguanylate cyclase - - - 0.00000000000000000000000000000000000001998 157.0
HFD2_k127_5655840_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 3.772e-204 638.0
HFD2_k127_5655840_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.000000000000000000000002501 102.0
HFD2_k127_5655840_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00006179 51.0
HFD2_k127_5657349_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 6.761e-267 848.0
HFD2_k127_5657349_1 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000007242 173.0
HFD2_k127_5657349_2 SNARE associated Golgi protein - - - 0.000000000000000000008371 100.0
HFD2_k127_5657349_3 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000003122 98.0
HFD2_k127_5657349_4 Polyprenyl synthetase K02523 - 2.5.1.90 0.000000000000003584 88.0
HFD2_k127_5657349_5 peptidyl-tyrosine sulfation - - - 0.0000001387 64.0
HFD2_k127_5657349_6 Domain of unknown function (DUF4870) - - - 0.00007869 51.0
HFD2_k127_5659603_0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 505.0
HFD2_k127_5659603_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 486.0
HFD2_k127_5659603_2 Thrombospondin type 3 repeat - - - 0.000000000000000000000001115 121.0
HFD2_k127_5659603_3 cellulase activity - - - 0.000001539 62.0
HFD2_k127_5659603_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.00001088 51.0
HFD2_k127_5671606_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 6.502e-256 822.0
HFD2_k127_5671606_1 Nucleotidyl transferase K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 462.0
HFD2_k127_5671606_2 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000008752 151.0
HFD2_k127_5671606_3 Tetratricopeptide repeat - - - 0.000003662 56.0
HFD2_k127_5671606_4 - - - - 0.000005708 55.0
HFD2_k127_5676603_0 Bacterial regulatory protein, Fis family K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 400.0
HFD2_k127_5676603_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000002007 151.0
HFD2_k127_5676603_10 Tetratricopeptide repeat - - - 0.00006063 54.0
HFD2_k127_5676603_2 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000004545 153.0
HFD2_k127_5676603_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000002832 148.0
HFD2_k127_5676603_4 GAF modulated sigma54 specific transcriptional regulator, Fis family K21405 - - 0.000000000000000004762 87.0
HFD2_k127_5676603_5 response regulator K02481,K07713 - - 0.00000000000000004096 96.0
HFD2_k127_5676603_6 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000001626 83.0
HFD2_k127_5676603_7 - - - - 0.000000009471 64.0
HFD2_k127_5676603_8 Glutaredoxin K03676 - - 0.00000002613 56.0
HFD2_k127_5676603_9 - - - - 0.000004675 49.0
HFD2_k127_5678161_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 548.0
HFD2_k127_5678161_1 Heparinase II/III-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 402.0
HFD2_k127_5678161_2 Glycosyl transferase, family 2 K00786 - - 0.00000000000000000000000000000000000000000000000000000003646 207.0
HFD2_k127_5678161_3 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000005539 105.0
HFD2_k127_5678161_4 - - - - 0.00000000000002387 88.0
HFD2_k127_5678161_5 Uncharacterized conserved protein (DUF2304) K09153 - - 0.0000000000001102 75.0
HFD2_k127_5678161_6 Membrane - - - 0.00000000005285 74.0
HFD2_k127_5678161_7 - - - - 0.000006003 57.0
HFD2_k127_5678161_8 Protein of unknown function (DUF2752) - - - 0.0000568 55.0
HFD2_k127_5698693_0 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 454.0
HFD2_k127_5698693_1 Two component transcriptional regulator, winged helix family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007819 283.0
HFD2_k127_5698693_2 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000001288 207.0
HFD2_k127_5698693_3 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.0000000000000000000000000000000000000000000000000005813 193.0
HFD2_k127_5698693_4 alginic acid biosynthetic process - - - 0.00000000000000000003935 104.0
HFD2_k127_5742231_0 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 567.0
HFD2_k127_5742231_1 COG1410 Methionine synthase I, cobalamin-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 341.0
HFD2_k127_5742231_2 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001156 297.0
HFD2_k127_5742231_3 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000195 210.0
HFD2_k127_5742231_4 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000385 198.0
HFD2_k127_5742231_5 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000001271 137.0
HFD2_k127_5742231_6 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.0000000000000000004564 90.0
HFD2_k127_5747913_0 IMG reference gene - - - 0.0000000000000000000000000000000000000000000256 183.0
HFD2_k127_5747913_1 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000001707 139.0
HFD2_k127_5756388_0 Peptidase, M16 K07263,K07623 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 437.0
HFD2_k127_5756388_1 PFAM Peptidase M16 inactive domain K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 421.0
HFD2_k127_5756388_2 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 357.0
HFD2_k127_5756388_3 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000001996 274.0
HFD2_k127_5756388_4 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000739 126.0
HFD2_k127_5756388_5 alpha/beta hydrolase fold - - - 0.000000000000000000000000000002424 127.0
HFD2_k127_5756388_6 Domain of unknown function (DUF4126) - - - 0.00000000000002755 76.0
HFD2_k127_5779638_0 transferase activity, transferring hexosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 471.0
HFD2_k127_5779638_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007729 430.0
HFD2_k127_5805054_0 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008313 501.0
HFD2_k127_5805054_1 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 479.0
HFD2_k127_5805054_10 Putative cyclase K07130 GO:0003674,GO:0003824,GO:0004061,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.0000000109 66.0
HFD2_k127_5805054_11 Tetratricopeptide repeat - - - 0.00007301 57.0
HFD2_k127_5805054_2 FAD binding domain K00486 - 1.14.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 430.0
HFD2_k127_5805054_3 Tryptophan 2,3-dioxygenase K00453 - 1.13.11.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008632 358.0
HFD2_k127_5805054_4 3-hydroxyanthranilic acid dioxygenase K00452 - 1.13.11.6 0.0000000000000000000000000000000000000000000000000000000000000009863 223.0
HFD2_k127_5805054_5 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000101 182.0
HFD2_k127_5805054_6 TPM domain K06872 - - 0.0000000000000000000000000000000000008703 150.0
HFD2_k127_5805054_7 PFAM LemA family K03744 - - 0.00000000000000000000000000000000004367 138.0
HFD2_k127_5805054_8 nucleotidyltransferase activity - - - 0.00000000000000000000000000000001653 136.0
HFD2_k127_5805054_9 oligosaccharyl transferase activity - - - 0.000000000000000000000000000001681 141.0
HFD2_k127_5808569_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000001097 177.0
HFD2_k127_5808569_1 TIGRFAM FeS cluster assembly scaffold protein NifU K04488 - - 0.0000000000000000000000000000000001912 136.0
HFD2_k127_5808569_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000009362 59.0
HFD2_k127_5808569_3 HEAT repeat - - - 0.00003237 53.0
HFD2_k127_5821972_0 involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 345.0
HFD2_k127_5821972_1 Pyridoxal-phosphate dependent enzyme K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 327.0
HFD2_k127_5821972_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001236 293.0
HFD2_k127_5821972_3 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000001429 270.0
HFD2_k127_5821972_4 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000132 263.0
HFD2_k127_5821972_5 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000001523 204.0
HFD2_k127_5821972_6 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000003241 199.0
HFD2_k127_5830465_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 437.0
HFD2_k127_5830465_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 389.0
HFD2_k127_5830465_10 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - 0.00000000000000000000001168 110.0
HFD2_k127_5830465_11 Protein of unknown function, DUF481 - - - 0.0006833 51.0
HFD2_k127_5830465_2 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008017 277.0
HFD2_k127_5830465_3 chlorophyll binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000344 255.0
HFD2_k127_5830465_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000004069 197.0
HFD2_k127_5830465_5 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000272 155.0
HFD2_k127_5830465_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000004451 160.0
HFD2_k127_5830465_7 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000004743 132.0
HFD2_k127_5830465_8 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000000001371 121.0
HFD2_k127_5830465_9 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000004621 120.0
HFD2_k127_5832621_0 4Fe-4S dicluster domain K00184 - - 0.0 1064.0
HFD2_k127_5832621_1 DNA polymerase A domain K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 473.0
HFD2_k127_5832621_2 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 337.0
HFD2_k127_5832621_3 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 300.0
HFD2_k127_5832621_4 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369,K13890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003646 283.0
HFD2_k127_5832621_5 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000004969 233.0
HFD2_k127_5832621_6 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000003231 163.0
HFD2_k127_5854741_0 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 532.0
HFD2_k127_5854741_1 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 496.0
HFD2_k127_5854741_10 - - - - 0.0000000000000000000000000001634 123.0
HFD2_k127_5854741_11 PFAM Uncharacterised protein family (UPF0153) - - - 0.00000000000000001685 87.0
HFD2_k127_5854741_12 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07659 - - 0.00000002007 63.0
HFD2_k127_5854741_13 Tetratricopeptide repeat - - - 0.0000002203 61.0
HFD2_k127_5854741_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 411.0
HFD2_k127_5854741_3 Aminotransferase class-V K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 342.0
HFD2_k127_5854741_4 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 309.0
HFD2_k127_5854741_5 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 292.0
HFD2_k127_5854741_6 Roadblock/LC7 domain - - - 0.00000000000000000000000000000000000000000000000000000001067 203.0
HFD2_k127_5854741_7 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000002924 184.0
HFD2_k127_5854741_8 Domain of unknown function (DUF4136) - - - 0.00000000000000000000000000000000000003445 149.0
HFD2_k127_5854741_9 Domain of unknown function (DUF4136) - - - 0.0000000000000000000000000000000000008029 146.0
HFD2_k127_5885477_0 Prolyl oligopeptidase family K01303 - 3.4.19.1 7.757e-257 815.0
HFD2_k127_5885477_1 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 516.0
HFD2_k127_5885477_2 Two component transcriptional regulator, LuxR family K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000002381 252.0
HFD2_k127_5885477_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003718 258.0
HFD2_k127_5885477_4 regulation of DNA-templated transcription, elongation - - - 0.000000000000000000000000000000000000000128 165.0
HFD2_k127_5885477_5 Acetyl xylan esterase (AXE1) K01060 - 3.1.1.41 0.0000000001727 74.0
HFD2_k127_5890867_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006652 375.0
HFD2_k127_5890867_1 PFAM PfkB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 338.0
HFD2_k127_5890867_10 - - - - 0.0000000000002929 73.0
HFD2_k127_5890867_2 3-oxoacid CoA-transferase, a subunit K01027,K01028,K01031,K01034 - 2.8.3.5,2.8.3.6,2.8.3.8,2.8.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 336.0
HFD2_k127_5890867_3 CoA-transferase activity K01027,K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002476 275.0
HFD2_k127_5890867_4 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000276 214.0
HFD2_k127_5890867_5 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000417 199.0
HFD2_k127_5890867_6 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759,K05606 - 4.4.1.5,5.1.99.1 0.0000000000000000000000000000000000003598 150.0
HFD2_k127_5890867_7 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000005328 132.0
HFD2_k127_5890867_8 - - - - 0.000000000000000000000000009147 127.0
HFD2_k127_5890867_9 regulator, PATAN and FRGAF domain-containing - - - 0.000000000000001461 82.0
HFD2_k127_5908377_0 aconitate hydratase K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000002485 251.0
HFD2_k127_5908377_1 polysaccharide deacetylase - - - 0.000000000000000000000000000000002301 144.0
HFD2_k127_5908377_2 Formyl transferase - - - 0.000000000000001266 85.0
HFD2_k127_5934144_0 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 369.0
HFD2_k127_5934144_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000003772 266.0
HFD2_k127_5937471_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 433.0
HFD2_k127_5937471_1 cAMP biosynthetic process K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001842 272.0
HFD2_k127_5948484_0 PFAM Integrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 305.0
HFD2_k127_5948484_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000009534 107.0
HFD2_k127_5948484_2 HlyD family secretion protein K01993 - - 0.000000005237 67.0
HFD2_k127_595153_0 PFAM peptidase U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 315.0
HFD2_k127_595153_1 peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 297.0
HFD2_k127_595153_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001425 267.0
HFD2_k127_595153_3 PFAM peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000000000638 184.0
HFD2_k127_5994835_0 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 292.0
HFD2_k127_5994835_1 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002763 263.0
HFD2_k127_5994835_2 Phosphoglycerate mutase family - - - 0.000000006681 61.0
HFD2_k127_5994835_3 YtxH-like protein - - - 0.00000001981 60.0
HFD2_k127_6003504_0 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 1.425e-221 725.0
HFD2_k127_6003504_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 557.0
HFD2_k127_6003504_2 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 312.0
HFD2_k127_6003504_3 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.000000000000000000000000000000000000000000000000000005564 197.0
HFD2_k127_6003504_4 DoxX-like family - - - 0.00000000000000000000000000000000000001638 148.0
HFD2_k127_6003504_5 nitric oxide dioxygenase activity - - - 0.0000000000000000000008757 101.0
HFD2_k127_6003504_6 Bacterial virulence protein (VirJ) - - - 0.0000000000002127 81.0
HFD2_k127_6003504_7 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog K03088 - - 0.0000000005671 68.0
HFD2_k127_6003504_8 Protein of unknown function (DUF1428) - - - 0.0000000006119 60.0
HFD2_k127_6016785_0 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 519.0
HFD2_k127_6016785_1 Zn peptidase - - - 0.000000000000000000000000000000000000000007182 178.0
HFD2_k127_604645_0 PFAM peptidase M16 domain protein - - - 0.00000000000000000000000000000000000000003082 164.0
HFD2_k127_604645_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000003637 137.0
HFD2_k127_6063904_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 407.0
HFD2_k127_6090145_0 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000002553 176.0
HFD2_k127_6090145_1 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000505 176.0
HFD2_k127_6090145_2 OsmC-like protein - - - 0.0000000000000000000000000000000000000000005575 161.0
HFD2_k127_6090145_3 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000001769 160.0
HFD2_k127_6120055_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 315.0
HFD2_k127_6120055_1 translation initiation inhibitor, yjgF family - - - 0.00000000000000000000000000000000137 137.0
HFD2_k127_6120055_2 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 0.00000000000000001204 93.0
HFD2_k127_6120055_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000002814 71.0
HFD2_k127_6120055_4 - - - - 0.000000000001208 80.0
HFD2_k127_6120055_5 - - - - 0.00000001167 66.0
HFD2_k127_613010_0 GAF domain - - - 0.000000000000000000000000000000000000000000001775 187.0
HFD2_k127_6130749_0 PFAM Formaldehyde-activating enzyme (Fae) K10713 - 4.2.1.147 0.000000000000000000000000000000000000000000000000000000000000000000004749 238.0
HFD2_k127_6130749_1 glutamyl-tRNA reductase activity K02407,K02492,K10714,K15671 GO:0005575,GO:0005623,GO:0009288,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000001137 223.0
HFD2_k127_6130749_2 ATP-grasp domain K01499,K06913 - 3.5.4.27 0.00000000000000003563 88.0
HFD2_k127_6130749_3 4-HFC-P synthase - - - 0.0008077 46.0
HFD2_k127_614297_0 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 579.0
HFD2_k127_614297_1 Argininosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 503.0
HFD2_k127_614297_2 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 392.0
HFD2_k127_614297_3 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 346.0
HFD2_k127_614297_4 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 327.0
HFD2_k127_614297_5 belongs to the lyase 1 family. Argininosuccinate lyase subfamily K01755,K14681 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000000000000000000000003618 118.0
HFD2_k127_614297_6 Serine protease with a broad substrate specificity K17734 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005509,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000009346 118.0
HFD2_k127_614297_7 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000005336 100.0
HFD2_k127_6162582_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000006339 152.0
HFD2_k127_6162582_1 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000014 139.0
HFD2_k127_6162582_2 positive regulation of growth rate - - - 0.000000000000000000000000000002786 138.0
HFD2_k127_6162582_3 Lamin Tail Domain - - - 0.0000007989 58.0
HFD2_k127_6162582_4 Glycosyl transferase family 41 - - - 0.0008079 53.0
HFD2_k127_6164329_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000003594 209.0
HFD2_k127_6164329_1 Rossmann-like domain - - - 0.0000000000000000000000000000000000000000004191 170.0
HFD2_k127_6164585_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 495.0
HFD2_k127_6164585_1 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 457.0
HFD2_k127_6164585_2 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 310.0
HFD2_k127_6164585_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 293.0
HFD2_k127_6164585_4 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000009088 246.0
HFD2_k127_6165155_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 6.951e-270 854.0
HFD2_k127_6165155_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007953 290.0
HFD2_k127_6165155_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K07025 - - 0.000000000000358 78.0
HFD2_k127_6165155_3 DNA protecting protein DprA K04096 - - 0.0000001587 55.0
HFD2_k127_6165285_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 405.0
HFD2_k127_6165285_1 Dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 366.0
HFD2_k127_6165285_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000003672 196.0
HFD2_k127_6165285_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000005765 186.0
HFD2_k127_6165285_4 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000005372 152.0
HFD2_k127_6165285_5 Could be involved in septation K06412 - - 0.00000000000000000000000000005574 121.0
HFD2_k127_6165285_6 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000002755 99.0
HFD2_k127_6165285_7 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000008891 93.0
HFD2_k127_6165285_8 VanZ like family - - - 0.000000000001557 78.0
HFD2_k127_6165285_9 - - - - 0.00000000002168 71.0
HFD2_k127_6168734_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.888e-279 889.0
HFD2_k127_6168734_1 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 314.0
HFD2_k127_6168734_2 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000002192 157.0
HFD2_k127_6168734_3 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000000009023 153.0
HFD2_k127_6168734_4 Hsp20/alpha crystallin family - - - 0.00000000000000000009649 95.0
HFD2_k127_6168734_5 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000004292 75.0
HFD2_k127_6168734_6 TonB C terminal K03832 - - 0.000000008949 61.0
HFD2_k127_6172915_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 361.0
HFD2_k127_6172915_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 308.0
HFD2_k127_6172915_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002141 255.0
HFD2_k127_6172915_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000006485 205.0
HFD2_k127_6172915_4 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000002885 167.0
HFD2_k127_6172915_5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K21681 - 1.1.1.405,2.7.7.40,2.7.7.60 0.000000000000000000000000000000000000000002016 167.0
HFD2_k127_618410_0 ABC transporter K06022,K06158,K10834 - 3.6.3.29,3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 479.0
HFD2_k127_618410_1 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000007083 239.0
HFD2_k127_618410_2 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000000000000001118 135.0
HFD2_k127_618410_3 3' exoribonuclease, RNase T-like - - - 0.00000000000000000000000000000000417 135.0
HFD2_k127_618410_4 Dodecin K09165 - - 0.00000000000000000000000001057 110.0
HFD2_k127_618410_5 PPIC-type PPIASE domain - - - 0.00000000009183 68.0
HFD2_k127_6184628_0 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008469 280.0
HFD2_k127_6184628_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000356 183.0
HFD2_k127_6184628_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000001829 154.0
HFD2_k127_6187611_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 8.479e-318 984.0
HFD2_k127_6187611_1 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 2.576e-298 941.0
HFD2_k127_6187611_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009221 322.0
HFD2_k127_6187611_3 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008736 311.0
HFD2_k127_6187611_4 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000788 242.0
HFD2_k127_6194944_0 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 574.0
HFD2_k127_6194944_1 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003547 304.0
HFD2_k127_6194944_2 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009761 284.0
HFD2_k127_6198132_0 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 524.0
HFD2_k127_6198132_1 Oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 489.0
HFD2_k127_6198132_2 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000000000004714 240.0
HFD2_k127_6198132_3 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000005409 232.0
HFD2_k127_6202428_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.109e-237 742.0
HFD2_k127_6202428_1 MacB-like periplasmic core domain - - - 6.841e-201 661.0
HFD2_k127_6202428_2 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 601.0
HFD2_k127_6202428_3 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 528.0
HFD2_k127_6202428_4 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 350.0
HFD2_k127_6202428_5 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 321.0
HFD2_k127_6239585_0 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 413.0
HFD2_k127_6249351_0 His Kinase A (phosphoacceptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 635.0
HFD2_k127_6249351_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 460.0
HFD2_k127_6249351_10 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000001951 243.0
HFD2_k127_6249351_11 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000672 252.0
HFD2_k127_6249351_12 PFAM ThiJ PfpI K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000004512 212.0
HFD2_k127_6249351_13 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000005939 209.0
HFD2_k127_6249351_14 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.00000000000000000000000000000000000000000000000000000002576 201.0
HFD2_k127_6249351_15 Nucleoside H+ symporter K05820 - - 0.0000000000000000000000000000000000000000000000000006218 201.0
HFD2_k127_6249351_16 NUDIX domain K00077,K01092,K03574,K03795 - 1.1.1.169,3.1.3.25,3.6.1.55,4.99.1.3 0.000000000000000000000000000000000000000000000000001091 197.0
HFD2_k127_6249351_17 PFAM short-chain dehydrogenase reductase SDR K00059,K00068,K03366 - 1.1.1.100,1.1.1.140,1.1.1.304,1.1.1.76 0.000000000000000000000000000000000000000000000000003768 198.0
HFD2_k127_6249351_18 PFAM glycine cleavage T protein (aminomethyl transferase) K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000006805 184.0
HFD2_k127_6249351_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000001394 165.0
HFD2_k127_6249351_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 427.0
HFD2_k127_6249351_20 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.0000000000000000000000000000000002359 134.0
HFD2_k127_6249351_21 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000001291 125.0
HFD2_k127_6249351_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000371 134.0
HFD2_k127_6249351_23 Domain of unknown function (DUF4154) - - - 0.00000000000000000000000000005558 126.0
HFD2_k127_6249351_24 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000003743 107.0
HFD2_k127_6249351_25 PFAM thioesterase superfamily K07107 - - 0.0000000000000000000000005264 119.0
HFD2_k127_6249351_26 acr, cog1430 K09005 - - 0.0000000000000000000000008588 111.0
HFD2_k127_6249351_27 PFAM cobalamin (vitamin B12) biosynthesis CbiX protein K03795 - 4.99.1.3 0.000000000000000000000003435 109.0
HFD2_k127_6249351_28 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000002882 101.0
HFD2_k127_6249351_29 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000002306 98.0
HFD2_k127_6249351_3 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 423.0
HFD2_k127_6249351_30 Soluble lytic murein transglycosylase L domain K08309 - - 0.00000000000000000008394 102.0
HFD2_k127_6249351_31 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 0.00000002064 57.0
HFD2_k127_6249351_4 helicase K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 407.0
HFD2_k127_6249351_5 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008843 356.0
HFD2_k127_6249351_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 354.0
HFD2_k127_6249351_7 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 334.0
HFD2_k127_6249351_8 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 319.0
HFD2_k127_6249351_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000005564 249.0
HFD2_k127_6257904_0 - K17285 - - 0.0 1326.0
HFD2_k127_6257904_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 514.0
HFD2_k127_6257904_10 FecR protein - - - 0.0000000123 66.0
HFD2_k127_6257904_2 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 499.0
HFD2_k127_6257904_3 histone H2A K63-linked ubiquitination K00925,K08884,K11894 - 2.7.11.1,2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 445.0
HFD2_k127_6257904_4 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase K00322 - 1.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 356.0
HFD2_k127_6257904_5 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000003859 231.0
HFD2_k127_6257904_6 ATPase activity - - - 0.000000000000000000000000000000000000000000000000000003125 208.0
HFD2_k127_6257904_7 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K01256,K02563,K02652,K08776,K12132 - 2.4.1.227,2.7.11.1,3.4.11.2 0.000000000000000000000000000000000000000003949 172.0
HFD2_k127_6257904_8 - - - - 0.00000000000000000000000000000000000000003044 177.0
HFD2_k127_6257904_9 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000005752 174.0
HFD2_k127_6279810_0 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 408.0
HFD2_k127_6279810_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000009194 254.0
HFD2_k127_6279810_2 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.0000000000000000000000000001278 116.0
HFD2_k127_6301377_0 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006586 366.0
HFD2_k127_6301377_1 - - - - 0.00000000000000000002293 96.0
HFD2_k127_6318714_0 SMART Integrin alpha beta-propellor repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 471.0
HFD2_k127_6318714_1 Protein of unknown function (DUF1579) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002279 257.0
HFD2_k127_6321623_0 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 310.0
HFD2_k127_6321623_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000003708 196.0
HFD2_k127_6321623_2 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000001181 197.0
HFD2_k127_6321623_3 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000001395 100.0
HFD2_k127_6321623_4 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.0000000000000001693 92.0
HFD2_k127_6349414_0 Oligopeptide transporter OPT - - - 1.27e-281 880.0
HFD2_k127_6349414_1 peptidyl-tyrosine sulfation K01277 - 3.4.14.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 527.0
HFD2_k127_6349414_2 Amino acid permease K20265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 328.0
HFD2_k127_6349414_3 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001515 286.0
HFD2_k127_6349414_4 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000000006273 231.0
HFD2_k127_6349414_5 Lecithin:cholesterol acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000004162 214.0
HFD2_k127_6349414_6 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000008118 97.0
HFD2_k127_6381944_0 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 463.0
HFD2_k127_6381944_1 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007265 292.0
HFD2_k127_6381944_2 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000005782 131.0
HFD2_k127_6381944_3 EVE domain - - - 0.00000000000000000000000000000004422 128.0
HFD2_k127_6381944_4 SMART Transport-associated and nodulation region - - - 0.0000000001631 73.0
HFD2_k127_6387234_0 Amidinotransferase - - - 0.0000000000000000000000000000000000000000000000000000000008996 218.0
HFD2_k127_6387234_1 Peptidase M56 - - - 0.0000000000000000000000000000000000001276 164.0
HFD2_k127_6387234_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000001424 140.0
HFD2_k127_6387234_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000002702 130.0
HFD2_k127_6387234_4 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000009331 63.0
HFD2_k127_6398495_0 Protein kinase domain K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 468.0
HFD2_k127_6404833_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 392.0
HFD2_k127_6404833_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 313.0
HFD2_k127_6404833_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 284.0
HFD2_k127_6404833_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002385 287.0
HFD2_k127_6404833_4 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001186 273.0
HFD2_k127_6404833_5 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000000000000001042 188.0
HFD2_k127_6411004_0 UDP-N-acetylmuramate-L-alanine ligase activity K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 553.0
HFD2_k127_6411004_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 460.0
HFD2_k127_6411004_10 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000003748 211.0
HFD2_k127_6411004_11 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000006738 197.0
HFD2_k127_6411004_12 CYTH K05873 - 4.6.1.1 0.0000000000000000000000000001475 121.0
HFD2_k127_6411004_13 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - 0.00000002925 65.0
HFD2_k127_6411004_14 Penicillin-binding Protein dimerisation domain K03587,K08384 - 3.4.16.4 0.0000001252 58.0
HFD2_k127_6411004_15 Phosphotransferase K07102 - 2.7.1.221 0.00004217 53.0
HFD2_k127_6411004_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 427.0
HFD2_k127_6411004_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 419.0
HFD2_k127_6411004_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 410.0
HFD2_k127_6411004_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 402.0
HFD2_k127_6411004_6 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 332.0
HFD2_k127_6411004_7 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 323.0
HFD2_k127_6411004_8 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008879 287.0
HFD2_k127_6411004_9 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003112 243.0
HFD2_k127_6430518_0 Malate synthase K01638 - 2.3.3.9 9.4e-235 739.0
HFD2_k127_6430518_1 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 1.501e-203 649.0
HFD2_k127_6430518_10 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000468 122.0
HFD2_k127_6430518_11 serine threonine protein kinase - - - 0.00000000000000001994 96.0
HFD2_k127_6430518_12 serine threonine protein kinase - - - 0.000000000000001058 90.0
HFD2_k127_6430518_13 - - - - 0.00000000001408 76.0
HFD2_k127_6430518_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 2.595e-203 643.0
HFD2_k127_6430518_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 417.0
HFD2_k127_6430518_4 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 331.0
HFD2_k127_6430518_5 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 288.0
HFD2_k127_6430518_6 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000276 247.0
HFD2_k127_6430518_7 Endonuclease V K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000009204 191.0
HFD2_k127_6430518_8 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000008556 158.0
HFD2_k127_6430518_9 Lipid A Biosynthesis N-terminal domain - - - 0.00000000000000000000000002723 111.0
HFD2_k127_6432124_0 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 313.0
HFD2_k127_6432124_1 - - - - 0.00000001892 68.0
HFD2_k127_6506937_0 PFAM peptidase M61 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 630.0
HFD2_k127_6506937_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 330.0
HFD2_k127_6516411_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 571.0
HFD2_k127_6516411_1 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002764 280.0
HFD2_k127_6516411_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003178 265.0
HFD2_k127_6516411_3 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000258 60.0
HFD2_k127_6556180_0 PFAM peptidase M16 domain protein K07263 - - 0.000000000000000000000000000000000000000000000000000000000001329 238.0
HFD2_k127_6556180_1 amine dehydrogenase activity - - - 0.0000004169 60.0
HFD2_k127_6556180_2 Belongs to the BolA IbaG family - - - 0.000007971 50.0
HFD2_k127_6566200_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 373.0
HFD2_k127_6566200_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001334 246.0
HFD2_k127_6566200_2 Ribosomal protein L4/L1 family K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000001101 227.0
HFD2_k127_6566200_3 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000006528 175.0
HFD2_k127_6566200_4 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000008878 140.0
HFD2_k127_6566200_5 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000009552 138.0
HFD2_k127_6566200_6 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000001591 126.0
HFD2_k127_6566200_7 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000002284 102.0
HFD2_k127_6566200_8 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000001704 76.0
HFD2_k127_6586387_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 1026.0
HFD2_k127_6586387_1 Heat shock protein DnaJ domain protein - - - 0.0000000000000000000000000000000000000000000005053 186.0
HFD2_k127_6586387_2 Methyltransferase domain - - - 0.000000000001111 74.0
HFD2_k127_65882_0 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 498.0
HFD2_k127_65882_1 MacB-like periplasmic core domain - - - 0.000000000000000002198 85.0
HFD2_k127_660168_0 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000104 247.0
HFD2_k127_660168_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000003053 122.0
HFD2_k127_660168_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000001978 103.0
HFD2_k127_660168_3 DNA-sulfur modification-associated - - - 0.0005631 49.0
HFD2_k127_6605519_0 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 1.531e-216 689.0
HFD2_k127_6605519_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 342.0
HFD2_k127_6605519_2 Belongs to the pseudouridine synthase RsuA family K06178,K06181,K06182 - 5.4.99.20,5.4.99.21,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000005438 248.0
HFD2_k127_6605519_3 bis(5'-adenosyl)-triphosphatase activity K19710 GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.7.53 0.000000000000000000000000000000000000000000006731 175.0
HFD2_k127_6605519_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000002326 161.0
HFD2_k127_6605519_5 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000000000000001966 140.0
HFD2_k127_6605519_6 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 0.0000000000000000000000000000000008191 142.0
HFD2_k127_6620149_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702,K08999 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 434.0
HFD2_k127_6620149_1 - - - - 0.0000000008398 70.0
HFD2_k127_6649110_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 386.0
HFD2_k127_6649110_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 385.0
HFD2_k127_6649110_10 - - - - 0.0000000006541 64.0
HFD2_k127_6649110_2 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001871 247.0
HFD2_k127_6649110_3 COG1225 Peroxiredoxin K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0032843,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000000001334 172.0
HFD2_k127_6649110_4 SurA N-terminal domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000002337 157.0
HFD2_k127_6649110_5 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.00000000000000000000000000002676 136.0
HFD2_k127_6649110_6 Aminotransferase class v - - - 0.000000000000000000000006548 109.0
HFD2_k127_6649110_7 COG2146 Ferredoxin subunits of nitrite reductase and K00363 - 1.7.1.15 0.000000000000000000002202 107.0
HFD2_k127_6649110_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000002585 92.0
HFD2_k127_6652221_0 COG2133 Glucose sorbosone dehydrogenases K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 301.0
HFD2_k127_6652221_1 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001031 271.0
HFD2_k127_6652221_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000006394 268.0
HFD2_k127_6652221_3 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002556 291.0
HFD2_k127_6652221_4 TonB dependent receptor K16087 - - 0.00000000000000000005384 103.0
HFD2_k127_6653153_0 Aldehyde dehydrogenase family K10217 - 1.2.1.32,1.2.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 620.0
HFD2_k127_6653153_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 490.0
HFD2_k127_6653153_2 Translation initiation inhibitor, yjgF family K15067 - 3.5.99.5 0.0000000000000000000000000000000000000000000007262 187.0
HFD2_k127_6653153_3 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.0000000000000000000000000000000001554 137.0
HFD2_k127_6669542_0 Domain of unknown function (DUF4070) - - - 9.754e-201 636.0
HFD2_k127_6669542_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 458.0
HFD2_k127_6669542_2 Amino acid permease K20265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004044 454.0
HFD2_k127_6669542_3 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 412.0
HFD2_k127_6669542_4 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007521 293.0
HFD2_k127_6669542_5 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000254 241.0
HFD2_k127_6669542_6 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.000000000000000000000000000000000000000000000000003784 205.0
HFD2_k127_6669542_7 Si dkey-190g11.3 - - - 0.0004832 51.0
HFD2_k127_6716579_0 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 419.0
HFD2_k127_6716579_1 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 377.0
HFD2_k127_6716579_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 383.0
HFD2_k127_6716579_3 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000001293 239.0
HFD2_k127_6716579_4 ACT domain K00928 - 2.7.2.4 0.00000000000000000000000000000000000000206 153.0
HFD2_k127_6716579_5 PFAM CBS domain containing protein - - - 0.00000000001901 78.0
HFD2_k127_6842804_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 2.93e-223 712.0
HFD2_k127_6842804_1 Dienelactone hydrolase family - - - 0.00000000000000000000000003525 120.0
HFD2_k127_6843069_0 phosphorelay signal transduction system - - - 0.00000000000000000000000000001382 130.0
HFD2_k127_6843069_1 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000002136 103.0
HFD2_k127_6843069_2 Belongs to the ompA family K03286 - - 0.00000000000000001279 96.0
HFD2_k127_6869804_0 PFAM Iron permease FTR1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 299.0
HFD2_k127_6869804_1 Belongs to the Fur family K03711 - - 0.000000000000000000000000000003179 125.0
HFD2_k127_6869804_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000004785 121.0
HFD2_k127_6880363_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008073 358.0
HFD2_k127_6880363_1 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000136 213.0
HFD2_k127_6880448_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 616.0
HFD2_k127_6880448_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 424.0
HFD2_k127_6880448_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000077 302.0
HFD2_k127_6880448_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001047 299.0
HFD2_k127_6880448_4 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000002247 252.0
HFD2_k127_6880448_5 ATP synthesis coupled proton transport K02109 - - 0.000000000000000000000000001607 119.0
HFD2_k127_6880448_6 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000004142 96.0
HFD2_k127_6880448_7 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00002439 51.0
HFD2_k127_6927077_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 323.0
HFD2_k127_693696_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 349.0
HFD2_k127_693696_1 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003571 261.0
HFD2_k127_693696_2 Phosphate transport system permease K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000002619 235.0
HFD2_k127_693696_3 Phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000001958 87.0
HFD2_k127_693696_4 thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0003634 47.0
HFD2_k127_6949430_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 451.0
HFD2_k127_6949430_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 420.0
HFD2_k127_6949430_2 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase K00322 - 1.6.1.1 0.0000000000000000000000000000000000001255 157.0
HFD2_k127_6963501_0 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 628.0
HFD2_k127_6963501_1 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 436.0
HFD2_k127_6963501_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 428.0
HFD2_k127_6963501_3 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 420.0
HFD2_k127_6963501_4 Biotin-lipoyl like K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 369.0
HFD2_k127_6963501_5 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 293.0
HFD2_k127_6963501_6 Sortase family K07284 - 3.4.22.70 0.00000000000000000000000000004079 124.0
HFD2_k127_6972511_0 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 293.0
HFD2_k127_6972511_1 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001105 267.0
HFD2_k127_6972511_2 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000008064 214.0
HFD2_k127_6972511_3 Elongation factor P K02356 - - 0.000000000000000000000000000000000000000007532 161.0
HFD2_k127_6972511_4 Putative stress-induced transcription regulator - - - 0.00000000000000000000000000000000000001214 153.0
HFD2_k127_6972511_5 Alpha beta hydrolase - - - 0.00000000000000000000001289 109.0
HFD2_k127_7027130_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 1.049e-248 794.0
HFD2_k127_7027130_1 PFAM secretion protein HlyD family protein K01993,K02005 - - 0.0000000000000000000000000000000000000000000000000000000000004898 213.0
HFD2_k127_7027130_2 PFAM secretion protein HlyD family protein K01993,K02005 - - 0.0000000000000000000000000000000000002367 147.0
HFD2_k127_7045775_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006699 530.0
HFD2_k127_7045775_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 481.0
HFD2_k127_7045775_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004154 303.0
HFD2_k127_7045775_3 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000003822 264.0
HFD2_k127_7049746_0 ThiC-associated domain K03147 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 3.407e-225 705.0
HFD2_k127_7049746_1 Protein kinase domain - - - 0.00000000000000002374 94.0
HFD2_k127_707521_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000002384 55.0
HFD2_k127_7075378_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001237 294.0
HFD2_k127_7075378_1 LmbE homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000002406 242.0
HFD2_k127_7075378_10 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000198 124.0
HFD2_k127_7075378_11 DUF based on E. rectale Gene description (DUF3880) K06320 - - 0.000000000007807 69.0
HFD2_k127_7075378_2 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000001936 222.0
HFD2_k127_7075378_3 WbqC-like protein family - - - 0.00000000000000000000000000000000000000000000000000000004564 212.0
HFD2_k127_7075378_4 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000024 191.0
HFD2_k127_7075378_5 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000003115 181.0
HFD2_k127_7075378_6 Glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000007478 186.0
HFD2_k127_7075378_7 PFAM Glycosyl transferases group 1 K13668 GO:0000009,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0033164,GO:0040007,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.346 0.00000000000000000000000000000000000000000003021 179.0
HFD2_k127_7075378_8 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000001894 161.0
HFD2_k127_7075378_9 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000003636 125.0
HFD2_k127_7124758_0 Domain of unknown function (DUF1998) K02336,K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.7.7.7 5.93e-294 947.0
HFD2_k127_7124758_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006379 469.0
HFD2_k127_7124758_2 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 349.0
HFD2_k127_7124758_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009294 331.0
HFD2_k127_7124758_4 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 310.0
HFD2_k127_7124758_5 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009995 311.0
HFD2_k127_7124758_6 COG3209 Rhs family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001599 314.0
HFD2_k127_7124758_7 Deoxynucleoside kinase K15518 - 2.7.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000001152 257.0
HFD2_k127_7124758_8 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859,K07566 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24,2.7.7.87 0.0000000000000000000000000000000002417 152.0
HFD2_k127_7124758_9 transposition, DNA-mediated K02342 - 2.7.7.7 0.0000000000000000000000003627 119.0
HFD2_k127_7175074_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.0 1362.0
HFD2_k127_7175074_1 PFAM Cytochrome b b6 domain - - - 9.583e-204 646.0
HFD2_k127_7175074_2 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 521.0
HFD2_k127_7175074_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000002372 144.0
HFD2_k127_7175074_4 chaperone-mediated protein complex assembly - - - 0.00000000000000000000000000007346 127.0
HFD2_k127_7175074_5 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000007999 110.0
HFD2_k127_7175074_6 Alginate export - - - 0.000000000000000003346 96.0
HFD2_k127_7175074_7 chaperone-mediated protein complex assembly - - - 0.0000008193 61.0
HFD2_k127_7178689_0 Permease YjgP YjgQ family protein K07091,K11720 - - 0.00000000000000000000000000000000000000000000000001491 198.0
HFD2_k127_7179886_0 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009981 470.0
HFD2_k127_7179886_1 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 376.0
HFD2_k127_7179886_2 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000004291 132.0
HFD2_k127_7179886_3 - - - - 0.000000000001633 70.0
HFD2_k127_7179886_4 Domain of unknown function (DUF4136) - - - 0.00000000009771 70.0
HFD2_k127_7187918_0 Sortilin, neurotensin receptor 3, - - - 0.0 1206.0
HFD2_k127_7187918_1 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 428.0
HFD2_k127_7187918_2 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 402.0
HFD2_k127_7187918_3 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 349.0
HFD2_k127_7187918_4 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 292.0
HFD2_k127_7187918_5 PFAM aldo keto reductase K07079 - - 0.0000000000000000000000000000000000000000000000000000000005269 218.0
HFD2_k127_7187918_6 - - - - 0.0000000156 66.0
HFD2_k127_7217071_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 321.0
HFD2_k127_7217071_1 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000002521 205.0
HFD2_k127_7217071_2 MOSC N-terminal beta barrel domain K07140 - - 0.0000000000000000000609 95.0
HFD2_k127_7224735_0 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 479.0
HFD2_k127_7224735_1 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 372.0
HFD2_k127_7224735_2 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.00000000000000000000000000000000000006091 146.0
HFD2_k127_7224735_3 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000002105 147.0
HFD2_k127_7224735_4 Histidine kinase - - - 0.0000000000000000000000000000000001561 153.0
HFD2_k127_72295_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 557.0
HFD2_k127_72295_1 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004587 246.0
HFD2_k127_7251799_0 Peptidase S9, prolyl oligopeptidase active site domain protein K01322 - 3.4.21.26 3.53e-259 819.0
HFD2_k127_7251799_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 465.0
HFD2_k127_7251799_2 protein conserved in bacteria K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000587 374.0
HFD2_k127_7251799_3 electron transfer activity K00428 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000747 215.0
HFD2_k127_7251799_4 Putative DNA-binding domain - - - 0.000000000000000000000000000000002868 147.0
HFD2_k127_7251799_5 - - - - 0.000000000000005674 78.0
HFD2_k127_7257532_0 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000004922 254.0
HFD2_k127_7257532_1 FES K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000001941 223.0
HFD2_k127_7257532_2 Domain of Unknown Function (DUF748) - - - 0.0001768 54.0
HFD2_k127_7266493_0 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002065 286.0
HFD2_k127_7266493_1 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009219 276.0
HFD2_k127_7266493_2 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000001539 258.0
HFD2_k127_7266493_3 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000001045 120.0
HFD2_k127_7266493_4 membrane - - - 0.0000000000000004786 83.0
HFD2_k127_7266493_5 - - - - 0.00000000000001024 74.0
HFD2_k127_7267761_0 Molybdopterin oxidoreductase - - - 4.911e-317 1009.0
HFD2_k127_7267761_1 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 321.0
HFD2_k127_7267761_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 299.0
HFD2_k127_7267761_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000001455 276.0
HFD2_k127_7267761_4 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000009556 232.0
HFD2_k127_7267761_5 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000001958 226.0
HFD2_k127_7267761_6 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.000000000000000000000000000000000643 149.0
HFD2_k127_7267761_7 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000001487 136.0
HFD2_k127_7267761_8 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000006232 97.0
HFD2_k127_7278740_0 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007229 493.0
HFD2_k127_7278740_1 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006361 428.0
HFD2_k127_7278740_2 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 395.0
HFD2_k127_7278740_3 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000005554 264.0
HFD2_k127_7278740_4 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000008709 219.0
HFD2_k127_7278740_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000002794 202.0
HFD2_k127_7278740_7 Stress-responsive transcriptional regulator - - - 0.0000000000002692 75.0
HFD2_k127_7281711_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005103 276.0
HFD2_k127_7281711_1 Bifunctional protein - - - 0.00000000000000000000000000000000000000000000000000000000000000003487 235.0
HFD2_k127_7281711_2 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000001005 230.0
HFD2_k127_7281711_3 D,d-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000005744 194.0
HFD2_k127_7281711_4 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000002739 188.0
HFD2_k127_7281711_5 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000001774 160.0
HFD2_k127_7281711_6 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000004262 142.0
HFD2_k127_7281711_7 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000008666 116.0
HFD2_k127_72853_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 580.0
HFD2_k127_72853_1 C-terminus of AA_permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 454.0
HFD2_k127_72853_2 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 378.0
HFD2_k127_72853_3 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 352.0
HFD2_k127_72853_4 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000003435 239.0
HFD2_k127_72853_5 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000001311 219.0
HFD2_k127_72853_6 Multidrug transporter K08161 - - 0.00000000000000000000000000000000000000000001554 178.0
HFD2_k127_7320976_0 Glycosyl hydrolase family 63 C-terminal domain - - - 0.0 1367.0
HFD2_k127_7320976_1 choline dehydrogenase activity - - - 2.379e-244 767.0
HFD2_k127_7320976_2 Amylo-alpha-1,6-glucosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 580.0
HFD2_k127_7320976_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 572.0
HFD2_k127_7320976_4 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 520.0
HFD2_k127_7320976_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006173 429.0
HFD2_k127_7320976_6 Major intrinsic protein K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 305.0
HFD2_k127_7320976_7 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000007254 208.0
HFD2_k127_7320976_8 1,4-alpha-glucan branching enzyme activity K00700 - 2.4.1.18 0.000000000433 63.0
HFD2_k127_7333760_0 PrkA AAA domain K07180 - - 0.0 1080.0
HFD2_k127_7333760_1 Belongs to the ClpA ClpB family K03696 - - 4.094e-289 909.0
HFD2_k127_7333760_10 ggdef domain - - - 0.0000000000000000000000000000000000000000000000009282 192.0
HFD2_k127_7333760_11 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000001079 174.0
HFD2_k127_7333760_12 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000000000005066 142.0
HFD2_k127_7333760_13 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000004452 115.0
HFD2_k127_7333760_14 Glycoprotease family K01409,K14742 - 2.3.1.234 0.00000000000000000000005319 109.0
HFD2_k127_7333760_15 Protein of unknown function (DUF465) - - - 0.00001362 51.0
HFD2_k127_7333760_16 Outer membrane protein (OmpH-like) K06142 - - 0.00002796 54.0
HFD2_k127_7333760_17 diguanylate cyclase - - - 0.00005019 55.0
HFD2_k127_7333760_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 310.0
HFD2_k127_7333760_3 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004374 287.0
HFD2_k127_7333760_4 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000593 283.0
HFD2_k127_7333760_5 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000007867 273.0
HFD2_k127_7333760_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005084 286.0
HFD2_k127_7333760_7 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000002489 241.0
HFD2_k127_7333760_8 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.000000000000000000000000000000000000000000000000007922 188.0
HFD2_k127_7333760_9 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000001339 192.0
HFD2_k127_7341721_0 Redoxin K06196 - - 0.00000000000000000008012 98.0
HFD2_k127_7341721_1 Protein of unknown function (DUF3187) - - - 0.00000000000001002 84.0
HFD2_k127_7359913_0 Lysine exporter protein LysE YggA - - - 0.00000000000000000000000000000000002024 143.0
HFD2_k127_7359913_1 Tetratricopeptide TPR_2 repeat protein K12600 - - 0.00000000000000000000000000000006422 142.0
HFD2_k127_7359913_2 Cold-shock protein K03704 - - 0.00000000000000000000004934 110.0
HFD2_k127_7359913_3 - - - - 0.0006739 50.0
HFD2_k127_7360289_0 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 2.347e-209 664.0
HFD2_k127_7360289_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 486.0
HFD2_k127_7360289_10 PFAM Peptidase family M20 M25 M40 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007784 287.0
HFD2_k127_7360289_11 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000009918 230.0
HFD2_k127_7360289_12 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000004268 233.0
HFD2_k127_7360289_13 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000001553 189.0
HFD2_k127_7360289_14 Peptidase M56 - - - 0.000000000000000000000001994 118.0
HFD2_k127_7360289_15 - - - - 0.00000000000000000003299 102.0
HFD2_k127_7360289_16 SLBB domain K02237 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000003531 94.0
HFD2_k127_7360289_17 cellulase activity K01387 - 3.4.24.3 0.000000004354 64.0
HFD2_k127_7360289_18 Tetratricopeptide repeat - - - 0.00000001165 67.0
HFD2_k127_7360289_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 488.0
HFD2_k127_7360289_3 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006104 387.0
HFD2_k127_7360289_4 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009396 365.0
HFD2_k127_7360289_5 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005778 335.0
HFD2_k127_7360289_6 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 332.0
HFD2_k127_7360289_7 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009286 298.0
HFD2_k127_7360289_8 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001232 304.0
HFD2_k127_7360289_9 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002129 297.0
HFD2_k127_7374504_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006425 451.0
HFD2_k127_7374504_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 323.0
HFD2_k127_7374504_2 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000009078 215.0
HFD2_k127_7374504_3 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000001706 166.0
HFD2_k127_7374504_4 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.000000000000000000000000000000000004142 158.0
HFD2_k127_7374504_5 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000001847 141.0
HFD2_k127_7374504_7 Rhomboid family K19225 - 3.4.21.105 0.0000000674 61.0
HFD2_k127_7374504_8 transport - - - 0.0004899 49.0
HFD2_k127_7437246_0 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000000000000000000000000000000005692 183.0
HFD2_k127_7437246_1 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000000001239 177.0
HFD2_k127_7437246_2 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.000000000000000000000000000000000000000000009618 175.0
HFD2_k127_7437246_3 chorismate mutase domain of gram positive AroA protein K13853 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000001724 178.0
HFD2_k127_7458485_0 Putative citrate transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 535.0
HFD2_k127_7458485_1 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 536.0
HFD2_k127_7458485_2 Protein of unknown function (DUF1579) - - - 0.0000000000000000001654 100.0
HFD2_k127_7458485_3 Protein of unknown function (DUF1579) - - - 0.000000000000003616 87.0
HFD2_k127_7461380_0 dehydrogenase - - - 1.191e-207 666.0
HFD2_k127_7461380_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 534.0
HFD2_k127_7461380_10 Tetratricopeptide repeat - - - 0.000000000000004004 83.0
HFD2_k127_7461380_11 - - - - 0.00000000000003023 75.0
HFD2_k127_7461380_12 Domain of unknown function (DUF4177) - - - 0.00000000000006329 73.0
HFD2_k127_7461380_13 Transmembrane and TPR repeat-containing protein - - - 0.0000000004586 69.0
HFD2_k127_7461380_14 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.000006047 57.0
HFD2_k127_7461380_15 - - - - 0.000009837 56.0
HFD2_k127_7461380_16 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.0001133 50.0
HFD2_k127_7461380_2 Family 5 K02035,K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 394.0
HFD2_k127_7461380_3 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042,K17468 - 2.9.1.1,4.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 390.0
HFD2_k127_7461380_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 320.0
HFD2_k127_7461380_5 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000007767 252.0
HFD2_k127_7461380_6 Binding-protein-dependent transport system inner membrane component K02033,K13890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007001 252.0
HFD2_k127_7461380_7 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000008226 246.0
HFD2_k127_7461380_8 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000007141 188.0
HFD2_k127_7461380_9 Cold shock K03704 - - 0.000000000000000000059 91.0
HFD2_k127_7489314_0 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 555.0
HFD2_k127_7489314_1 Response regulator receiver - - - 0.000000000000000000000006155 111.0
HFD2_k127_7489314_2 Peptidase U62 modulator of DNA gyrase K03592 - - 0.0000001331 55.0
HFD2_k127_7495787_0 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 505.0
HFD2_k127_7495787_1 Heparinase II/III-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009627 396.0
HFD2_k127_7495787_2 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 364.0
HFD2_k127_7495787_3 Glutamine amidotransferase domain K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000001083 207.0
HFD2_k127_7495787_4 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000007169 166.0
HFD2_k127_7501391_0 Catalyzes the interconversion of ornithine to glutamate semialdehyde K00819 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 545.0
HFD2_k127_7501391_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 457.0
HFD2_k127_7501391_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 432.0
HFD2_k127_7501391_3 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 365.0
HFD2_k127_7501391_4 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001831 281.0
HFD2_k127_7501391_5 6-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000001781 214.0
HFD2_k127_7501391_6 denitrification pathway - - - 0.00000000000000000000000000000002296 133.0
HFD2_k127_7501391_7 PFAM thioesterase superfamily K02614 - - 0.00000000000000003682 86.0
HFD2_k127_7511624_0 Surface antigen K07277,K09800 - - 0.00000000000000000000000000000000000000000000000000000000002348 226.0
HFD2_k127_7511624_1 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000168 177.0
HFD2_k127_7511624_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000002223 177.0
HFD2_k127_7524764_0 PFAM Type II secretion system protein E K02454,K02504,K02652 - - 1.008e-255 800.0
HFD2_k127_7524764_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009948 543.0
HFD2_k127_7524764_2 phosphorelay signal transduction system K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 482.0
HFD2_k127_7524764_3 Type II secretion system (T2SS), protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 462.0
HFD2_k127_7524764_4 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001062 295.0
HFD2_k127_7524764_5 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000001338 193.0
HFD2_k127_7524764_6 Mannosyltransferase (PIG-V) - - - 0.0000000000000000000000000000002517 142.0
HFD2_k127_7524764_7 Psort location CytoplasmicMembrane, score - - - 0.00000000000000002687 93.0
HFD2_k127_7524764_8 - - - - 0.0000000000005595 81.0
HFD2_k127_7524764_9 - - - - 0.00004649 48.0
HFD2_k127_7533702_0 peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006319 542.0
HFD2_k127_7533702_1 5TM C-terminal transporter carbon starvation CstA K06200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 415.0
HFD2_k127_7533702_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 365.0
HFD2_k127_7550086_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 606.0
HFD2_k127_7550086_1 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000002819 280.0
HFD2_k127_7550086_2 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000001111 216.0
HFD2_k127_7550086_3 LytTr DNA-binding domain K02477,K07705,K21696 GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - 0.000000000000000000000000000000000000000000000001615 192.0
HFD2_k127_7550086_4 Histidine kinase - - - 0.000000000000000000000000000000000000000001191 171.0
HFD2_k127_7550086_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000509 164.0
HFD2_k127_7550086_6 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000001028 134.0
HFD2_k127_7553521_0 Oligopeptide/dipeptide transporter, C-terminal region K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 403.0
HFD2_k127_7553521_1 COG3119 Arylsulfatase A and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000181 267.0
HFD2_k127_7553521_2 efflux transmembrane transporter activity K12340 - - 0.000000000000000000000000000000000000000000000001546 197.0
HFD2_k127_7553521_3 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.0000000000000000000000000000002869 127.0
HFD2_k127_7553521_4 Belongs to the ABC transporter superfamily K02031 - - 0.000000000004356 68.0
HFD2_k127_7553521_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000595 68.0
HFD2_k127_7569625_0 PFAM Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000000000000000008557 203.0
HFD2_k127_7569625_1 Transcriptional regulatory protein, C terminal - - - 0.0000000000003667 75.0
HFD2_k127_7613768_0 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 458.0
HFD2_k127_7613768_1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000637 124.0
HFD2_k127_7636941_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 560.0
HFD2_k127_7636941_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004228 454.0
HFD2_k127_7636941_10 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000397 81.0
HFD2_k127_7636941_11 Belongs to the UPF0109 family K06960 - - 0.000000000000129 75.0
HFD2_k127_7636941_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 364.0
HFD2_k127_7636941_3 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 296.0
HFD2_k127_7636941_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007081 254.0
HFD2_k127_7636941_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000001039 213.0
HFD2_k127_7636941_6 riboflavin synthase, alpha K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000001602 203.0
HFD2_k127_7636941_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000003869 163.0
HFD2_k127_7636941_8 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000001898 147.0
HFD2_k127_7636941_9 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000001815 80.0
HFD2_k127_7645644_0 Peptidase, family M49 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005348 358.0
HFD2_k127_7645644_1 acetyltransferase - - - 0.0001721 53.0
HFD2_k127_7684079_0 Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 441.0
HFD2_k127_7684079_1 COG3901 Regulator of nitric oxide reductase transcription K19339,K19343 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 430.0
HFD2_k127_7684079_2 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003616 253.0
HFD2_k127_7684079_3 Memo-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001529 265.0
HFD2_k127_7684079_4 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000006379 139.0
HFD2_k127_7685238_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 455.0
HFD2_k127_7685238_1 Carbon starvation protein CstA K06200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 402.0
HFD2_k127_7685238_2 PFAM Uncharacterised protein family UPF0079, ATPase K06925 - - 0.000000000000000000000000000000006967 132.0
HFD2_k127_7685238_3 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.0001622 52.0
HFD2_k127_7701179_0 lysine biosynthetic process via aminoadipic acid - - - 1.244e-211 696.0
HFD2_k127_7701179_1 POT family K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 440.0
HFD2_k127_7766531_0 cellulose binding - - - 0.0 1074.0
HFD2_k127_7766531_1 tartrate metabolic process K01676,K01678 - 4.2.1.2 2.085e-202 638.0
HFD2_k127_7766531_2 - - - - 0.00000000000000000000002008 107.0
HFD2_k127_7773127_0 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000142 163.0
HFD2_k127_7773127_1 Isocitrate/isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000007749 97.0
HFD2_k127_7773127_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.0000000000001383 84.0
HFD2_k127_7773612_0 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000008512 251.0
HFD2_k127_7773612_1 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000005337 220.0
HFD2_k127_7773612_2 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000001823 204.0
HFD2_k127_7773612_3 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000001367 62.0
HFD2_k127_7843176_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 592.0
HFD2_k127_7843176_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003054 306.0
HFD2_k127_7843176_2 ABC-type multidrug transport system ATPase component - - - 0.0000000000000000000000000000000000000000000000000000000000000000001409 241.0
HFD2_k127_7843176_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000134 177.0
HFD2_k127_7843176_4 - - - - 0.0000000000000001061 96.0
HFD2_k127_7843176_5 Outer membrane efflux protein K12340 - - 0.0005096 49.0
HFD2_k127_7890897_0 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005613 434.0
HFD2_k127_7890897_1 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 288.0
HFD2_k127_7890897_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000009306 171.0
HFD2_k127_7890897_3 PFAM FIST C domain - - - 0.000000000000000000000000000000000000006145 161.0
HFD2_k127_7890897_4 spore germination - - - 0.00000000000000000000000000001607 131.0
HFD2_k127_7890897_5 transposition, DNA-mediated K02342 - 2.7.7.7 0.0000000000000000004982 100.0
HFD2_k127_7890897_6 methionine synthase - - - 0.0000000000000001004 88.0
HFD2_k127_7890897_7 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000001799 87.0
HFD2_k127_7907275_0 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000006096 231.0
HFD2_k127_7907275_1 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000002062 113.0
HFD2_k127_7907275_2 Collagen, type XV, alpha 1b K06823,K08135 GO:0005575,GO:0005576,GO:0005581,GO:0005582,GO:0005604,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0012505,GO:0016020,GO:0016021,GO:0023052,GO:0030574,GO:0031012,GO:0031224,GO:0031974,GO:0032963,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044420,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0062023,GO:0065007,GO:0070013,GO:0098651 - 0.0000003449 61.0
HFD2_k127_7950804_0 PFAM SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 392.0
HFD2_k127_7950804_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000001422 195.0
HFD2_k127_7950804_2 MgtC family - - - 0.0000000000000000000000000000000001304 141.0
HFD2_k127_7964342_0 phosphorelay signal transduction system - - - 0.000000000000000000000001506 112.0
HFD2_k127_7964342_1 chlorophyll binding - - - 0.00000000000000007579 94.0
HFD2_k127_7964342_2 AI-2E family transporter - - - 0.000000000592 72.0
HFD2_k127_8002755_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02474,K13015 - 1.1.1.136 5.27e-259 841.0
HFD2_k127_8002755_1 Pyridoxal-phosphate dependent enzyme K01751 - 4.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 302.0
HFD2_k127_8002755_2 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000006364 231.0
HFD2_k127_8020718_0 Biogenesis protein - - - 0.000000000000007717 84.0
HFD2_k127_8020718_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000007318 81.0
HFD2_k127_8020718_2 membrane K11622 - - 0.00000009674 63.0
HFD2_k127_8020718_3 Helix-turn-helix domain - - - 0.0006012 50.0
HFD2_k127_8025471_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 3.513e-257 807.0
HFD2_k127_8025471_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 431.0
HFD2_k127_8025471_2 SAM-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 374.0
HFD2_k127_8041979_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 577.0
HFD2_k127_8041979_1 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 400.0
HFD2_k127_8041979_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 306.0
HFD2_k127_8041979_3 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000001104 162.0
HFD2_k127_8075371_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 412.0
HFD2_k127_8075371_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000001074 237.0
HFD2_k127_8075371_2 TIGRFAM lipopolysaccharide heptosyltransferase II K02843 - - 0.000000000000000000000000000000000000000000000000000000001092 218.0
HFD2_k127_8075371_3 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.000000000000000000000000000000001162 145.0
HFD2_k127_8075371_4 - - - - 0.000000000000000000000000000000003367 136.0
HFD2_k127_8075371_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.00000000000002776 77.0
HFD2_k127_8075371_6 kinase activity - - - 0.0000000005338 72.0
HFD2_k127_8075371_7 lipopolysaccharide heptosyltransferase K02841,K02843 - - 0.0000004751 54.0
HFD2_k127_8087255_0 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 303.0
HFD2_k127_8087255_1 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006382 306.0
HFD2_k127_8087255_2 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004871 265.0
HFD2_k127_8087255_3 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002588 261.0
HFD2_k127_8087255_4 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000000000000000001635 239.0
HFD2_k127_8087255_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000001546 240.0
HFD2_k127_8087255_6 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000007914 168.0
HFD2_k127_8087255_7 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000007912 123.0
HFD2_k127_8087255_8 Belongs to the Fur family K09825 - - 0.00000000000000000000000465 108.0
HFD2_k127_8133155_0 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 1.561e-199 632.0
HFD2_k127_8133155_1 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase K00322 - 1.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 515.0
HFD2_k127_8133155_2 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 444.0
HFD2_k127_8133155_3 PFAM Thiolase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 419.0
HFD2_k127_8133155_4 Biotin-lipoyl like K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 409.0
HFD2_k127_8133155_5 - - - - 0.0000000000000000000000000000000000000000000000000000000002082 209.0
HFD2_k127_8133155_6 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000003017 168.0
HFD2_k127_8133155_7 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000000004412 138.0
HFD2_k127_8133155_8 transposition, DNA-mediated K02342 - 2.7.7.7 0.0000000000000000001169 102.0
HFD2_k127_8143492_0 helicase activity - - - 5.184e-275 866.0
HFD2_k127_8143492_1 Predicted membrane protein (DUF2157) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 411.0
HFD2_k127_8143492_2 Esterase of the alpha-beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000003548 261.0
HFD2_k127_8143492_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004699 246.0
HFD2_k127_8143492_4 Domain of unknown function (DUF4824) - - - 0.00000000000000000000000000000000000000772 167.0
HFD2_k127_8143492_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000004063 145.0
HFD2_k127_8143492_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000004604 115.0
HFD2_k127_8197739_0 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 622.0
HFD2_k127_8197739_1 PFAM Sodium sulphate symporter K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006991 497.0
HFD2_k127_8197739_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000009917 90.0
HFD2_k127_8204818_0 COG1680 Beta-lactamase class C and other penicillin binding proteins K01286,K08641 - 3.4.13.22,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 622.0
HFD2_k127_8204818_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 429.0
HFD2_k127_8204818_2 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000678 235.0
HFD2_k127_8204818_3 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000003464 190.0
HFD2_k127_8204818_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000001267 200.0
HFD2_k127_8204818_5 KR domain K03793 - 1.5.1.33 0.000000000000000000000000000000000000000001837 164.0
HFD2_k127_8204818_6 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000002449 171.0
HFD2_k127_8204818_7 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000555 124.0
HFD2_k127_8204818_8 Saccharopine dehydrogenase NADP binding domain - - - 0.000000000000001803 89.0
HFD2_k127_8204818_9 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000004737 76.0
HFD2_k127_8205170_0 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 376.0
HFD2_k127_8205170_1 Alanine dehydrogenase/PNT, C-terminal domain K07538 - 1.1.1.368 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 345.0
HFD2_k127_8205170_2 TIGRFAM CoA-substrate-specific enzyme activase - - - 0.000000000000000003704 96.0
HFD2_k127_8224470_0 signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 449.0
HFD2_k127_8224470_1 electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000191 256.0
HFD2_k127_8224470_2 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000001527 213.0
HFD2_k127_8224470_3 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000001714 217.0
HFD2_k127_8224470_4 Protein-disulfide isomerase - - - 0.000000000000000000000000000000000000000001143 160.0
HFD2_k127_8224470_5 - - - - 0.0000000000000000000000000000000578 141.0
HFD2_k127_8224470_6 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000002803 123.0
HFD2_k127_8224470_7 MatE - - - 0.00000000000000000005193 104.0
HFD2_k127_8224470_8 PFAM DSBA oxidoreductase - - - 0.0001568 54.0
HFD2_k127_8243464_0 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 362.0
HFD2_k127_8243464_1 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000003235 189.0
HFD2_k127_8243464_2 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000004204 194.0
HFD2_k127_8243464_3 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000109 182.0
HFD2_k127_8269232_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006162 474.0
HFD2_k127_8269232_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 304.0
HFD2_k127_8269232_2 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005263 286.0
HFD2_k127_8269232_3 Fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001125 268.0
HFD2_k127_8269232_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000006472 221.0
HFD2_k127_8269232_5 PSP1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000369 224.0
HFD2_k127_8269232_6 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000222 226.0
HFD2_k127_8269232_7 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000002519 199.0
HFD2_k127_8309032_0 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 448.0
HFD2_k127_8309032_1 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000002529 238.0
HFD2_k127_8309032_2 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000000000000003335 241.0
HFD2_k127_8309032_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000001935 211.0
HFD2_k127_8314851_0 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 505.0
HFD2_k127_8314851_1 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 397.0
HFD2_k127_8314851_2 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 365.0
HFD2_k127_8314851_3 nUDIX hydrolase K01515,K03574,K03801,K08310 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008828,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017144,GO:0018130,GO:0019177,GO:0019438,GO:0019752,GO:0034641,GO:0042364,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0046872,GO:0047429,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.181,3.6.1.13,3.6.1.55,3.6.1.67 0.000000000000000000000001871 114.0
HFD2_k127_8314851_4 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000003137 92.0
HFD2_k127_8315686_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.487e-263 833.0
HFD2_k127_8315686_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 493.0
HFD2_k127_8315686_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 322.0
HFD2_k127_8315686_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000804 210.0
HFD2_k127_8315686_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000003164 104.0
HFD2_k127_8315686_5 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000004684 59.0
HFD2_k127_8334449_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000008031 224.0
HFD2_k127_8334449_1 Putative metal-binding motif - - - 0.00000000000000000000001133 118.0
HFD2_k127_8334449_2 GDP-dissociation inhibitor activity. It is involved in the biological process described with regulation of G-protein coupled receptor protein signaling pathway K15837,K15839 GO:0000132,GO:0000139,GO:0000226,GO:0000278,GO:0000922,GO:0001709,GO:0001965,GO:0003674,GO:0005092,GO:0005096,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005783,GO:0005789,GO:0005794,GO:0005813,GO:0005815,GO:0005819,GO:0005829,GO:0005856,GO:0005886,GO:0005938,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007052,GO:0007154,GO:0007163,GO:0007165,GO:0007186,GO:0007264,GO:0007265,GO:0007275,GO:0007346,GO:0007399,GO:0007400,GO:0007405,GO:0008022,GO:0008047,GO:0008104,GO:0008150,GO:0008277,GO:0008283,GO:0008356,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009987,GO:0010506,GO:0010508,GO:0010564,GO:0010638,GO:0010646,GO:0012505,GO:0014016,GO:0014017,GO:0015630,GO:0016020,GO:0016043,GO:0016239,GO:0016241,GO:0017145,GO:0019222,GO:0019904,GO:0022008,GO:0022402,GO:0023051,GO:0023052,GO:0030010,GO:0030154,GO:0030234,GO:0030695,GO:0031090,GO:0031291,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0031974,GO:0031981,GO:0031984,GO:0032091,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032886,GO:0032991,GO:0033036,GO:0033043,GO:0034260,GO:0035556,GO:0036445,GO:0040001,GO:0042175,GO:0042802,GO:0043085,GO:0043086,GO:0043087,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043393,GO:0043547,GO:0043621,GO:0044087,GO:0044089,GO:0044092,GO:0044093,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044430,GO:0044431,GO:0044432,GO:0044444,GO:0044446,GO:0044448,GO:0044464,GO:0044877,GO:0045165,GO:0045167,GO:0045175,GO:0045177,GO:0045179,GO:0045185,GO:0045787,GO:0048103,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048699,GO:0048731,GO:0048856,GO:0048863,GO:0048865,GO:0048867,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050795,GO:0050896,GO:0051098,GO:0051099,GO:0051100,GO:0051128,GO:0051130,GO:0051179,GO:0051234,GO:0051235,GO:0051293,GO:0051294,GO:0051301,GO:0051336,GO:0051345,GO:0051346,GO:0051493,GO:0051495,GO:0051640,GO:0051641,GO:0051642,GO:0051649,GO:0051651,GO:0051653,GO:0051656,GO:0051657,GO:0051661,GO:0051716,GO:0051726,GO:0055057,GO:0055059,GO:0060236,GO:0060259,GO:0060341,GO:0060589,GO:0061351,GO:0061842,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070507,GO:0070840,GO:0071840,GO:0071944,GO:0072089,GO:0072686,GO:0090068,GO:0090169,GO:0090224,GO:0097431,GO:0097574,GO:0097575,GO:0098588,GO:0098722,GO:0098772,GO:0098791,GO:0098827,GO:0099568,GO:0099738,GO:1902115,GO:1902117,GO:1902850,GO:1903047,GO:1903827,GO:1903829,GO:1904375,GO:1904377,GO:1904424,GO:1904776,GO:1904778,GO:1905097,GO:1905098,GO:1905832 - 0.0000000000000000000001209 113.0
HFD2_k127_8391305_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008458 323.0
HFD2_k127_8391305_1 Putative transposase - - - 0.00000000000000000000000000000000000003932 152.0
HFD2_k127_8391305_2 Transposase - - - 0.0000000000000000000000000000002577 126.0
HFD2_k127_8391305_3 Transposase - - - 0.0000000000000000000001166 102.0
HFD2_k127_8391305_4 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000003418 97.0
HFD2_k127_8391305_5 Transposase - - - 0.0000000002869 72.0
HFD2_k127_8413092_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009596 434.0
HFD2_k127_8413092_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003589 244.0
HFD2_k127_8413092_2 Sporulation delaying protein SdpA - - - 0.000000000000000000002558 108.0
HFD2_k127_8413092_3 Glycosyl transferase family 2 K10012,K20534 - 2.4.2.53 0.0000000006385 63.0
HFD2_k127_8413092_4 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000006475 63.0
HFD2_k127_8419360_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 480.0
HFD2_k127_8419360_1 ATPase family associated with various cellular activities (AAA) K06027 - 3.6.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 416.0
HFD2_k127_8419360_10 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000008954 137.0
HFD2_k127_8419360_11 Multicopper oxidase K04753 - - 0.00000000000000000000000007489 125.0
HFD2_k127_8419360_12 Thrombospondin C-terminal region K04659 GO:0000902,GO:0001501,GO:0001503,GO:0001932,GO:0001934,GO:0001936,GO:0001938,GO:0001968,GO:0002020,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0002688,GO:0002690,GO:0003416,GO:0003417,GO:0003674,GO:0005102,GO:0005178,GO:0005198,GO:0005201,GO:0005488,GO:0005496,GO:0005499,GO:0005509,GO:0005515,GO:0005518,GO:0005539,GO:0005575,GO:0005576,GO:0005604,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005912,GO:0005924,GO:0005927,GO:0006928,GO:0006950,GO:0007155,GO:0007160,GO:0007275,GO:0007399,GO:0007517,GO:0007610,GO:0008150,GO:0008201,GO:0008284,GO:0008289,GO:0009653,GO:0009790,GO:0009887,GO:0009888,GO:0009893,GO:0009987,GO:0010562,GO:0010604,GO:0010941,GO:0012505,GO:0014812,GO:0016043,GO:0016203,GO:0016477,GO:0016525,GO:0016528,GO:0016529,GO:0019220,GO:0019222,GO:0019842,GO:0019899,GO:0021700,GO:0022008,GO:0022603,GO:0022607,GO:0022610,GO:0030030,GO:0030054,GO:0030055,GO:0030154,GO:0030182,GO:0030198,GO:0030334,GO:0030335,GO:0030855,GO:0031012,GO:0031175,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0031589,GO:0031594,GO:0032101,GO:0032103,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032879,GO:0032989,GO:0032990,GO:0032991,GO:0033554,GO:0033555,GO:0033627,GO:0034103,GO:0034976,GO:0035265,GO:0035989,GO:0036094,GO:0040007,GO:0040011,GO:0040012,GO:0040017,GO:0042127,GO:0042325,GO:0042327,GO:0042981,GO:0043062,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043236,GO:0043237,GO:0043394,GO:0043395,GO:0043931,GO:0043933,GO:0044085,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045202,GO:0045765,GO:0045937,GO:0046872,GO:0048265,GO:0048266,GO:0048468,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048589,GO:0048646,GO:0048666,GO:0048699,GO:0048705,GO:0048731,GO:0048736,GO:0048799,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050678,GO:0050679,GO:0050730,GO:0050731,GO:0050789,GO:0050793,GO:0050794,GO:0050839,GO:0050840,GO:0050896,GO:0050920,GO:0050921,GO:0051093,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051216,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0051270,GO:0051272,GO:0051451,GO:0051674,GO:0051716,GO:0060173,GO:0060231,GO:0060255,GO:0060343,GO:0060346,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060429,GO:0060538,GO:0060548,GO:0061053,GO:0061061,GO:0061383,GO:0061430,GO:0061448,GO:0062023,GO:0065003,GO:0065007,GO:0070161,GO:0070977,GO:0071603,GO:0071622,GO:0071624,GO:0071695,GO:0071840,GO:0080090,GO:0090022,GO:0090023,GO:0090136,GO:0097159,GO:0097367,GO:0098609,GO:0098868,GO:0120036,GO:0120039,GO:1901342,GO:1901343,GO:1901681,GO:1902622,GO:1902624,GO:2000026,GO:2000145,GO:2000147,GO:2000181 - 0.0000000000000000007476 102.0
HFD2_k127_8419360_13 protein-disulfide reductase activity - - - 0.00000000003466 71.0
HFD2_k127_8419360_2 Required for chromosome condensation and partitioning K03529 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 439.0
HFD2_k127_8419360_3 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 403.0
HFD2_k127_8419360_4 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 350.0
HFD2_k127_8419360_5 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000007401 259.0
HFD2_k127_8419360_6 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000005728 235.0
HFD2_k127_8419360_7 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000006813 227.0
HFD2_k127_8419360_8 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.0000000000000000000000000000000000000000000000000000002476 203.0
HFD2_k127_8419360_9 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000005385 209.0
HFD2_k127_8423988_0 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 511.0
HFD2_k127_8423988_1 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 443.0
HFD2_k127_8423988_2 POT family K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009218 261.0
HFD2_k127_8438253_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 519.0
HFD2_k127_8438253_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 333.0
HFD2_k127_8438253_2 Tellurite resistance protein TerB - - - 0.0000000000000000000000000000000000000000000000000003266 194.0
HFD2_k127_8438253_3 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000003408 64.0
HFD2_k127_8440437_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000004715 237.0
HFD2_k127_8440437_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000003594 174.0
HFD2_k127_8440437_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000002366 139.0
HFD2_k127_8440437_3 Tetratricopeptide repeat - - - 0.000000000005541 80.0
HFD2_k127_8453195_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 299.0
HFD2_k127_8453195_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001735 294.0
HFD2_k127_8453195_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000001831 172.0
HFD2_k127_8453195_3 Sporulation and spore germination K06298 - - 0.000000000000000002955 91.0
HFD2_k127_8456939_0 non-ribosomal peptide synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 565.0
HFD2_k127_8471995_0 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000103 206.0
HFD2_k127_8471995_1 regulator, PATAN and FRGAF domain-containing - - - 0.00000000000000000000000000001975 132.0
HFD2_k127_8471995_2 zinc-ribbon domain - - - 0.00000000000000006622 95.0
HFD2_k127_8476397_0 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 503.0
HFD2_k127_8476397_1 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 424.0
HFD2_k127_8476397_2 EVE domain - - - 0.000000000000000000000000000000001684 135.0
HFD2_k127_8476397_3 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K01838 - 5.4.2.6 0.00000000000000000000000000000001222 136.0
HFD2_k127_8476397_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.000000000000000000000008964 118.0
HFD2_k127_8476397_5 5'-nucleotidase - - - 0.00000000000000000003936 106.0
HFD2_k127_8476397_6 5'-nucleotidase - - - 0.000000000000001109 92.0
HFD2_k127_8476397_7 Thioredoxin-like domain - - - 0.00000000000001764 88.0
HFD2_k127_8522262_0 Bacterial protein of unknown function (DUF885) - - - 7.508e-211 673.0
HFD2_k127_8522262_1 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 536.0
HFD2_k127_8522262_10 antisigma factor binding K04749 - - 0.0000003016 61.0
HFD2_k127_8522262_11 repeat-containing protein - - - 0.0002636 53.0
HFD2_k127_8522262_2 Sugar (and other) transporter K08369 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 476.0
HFD2_k127_8522262_3 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007346 403.0
HFD2_k127_8522262_4 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 380.0
HFD2_k127_8522262_5 response regulator, receiver K13069,K18967 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006199 287.0
HFD2_k127_8522262_6 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009687 284.0
HFD2_k127_8522262_7 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000003468 240.0
HFD2_k127_8522262_8 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000004304 202.0
HFD2_k127_8522262_9 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.0000000000000000000000000001445 121.0
HFD2_k127_8534558_0 B12 binding domain - - - 1.299e-230 730.0
HFD2_k127_8534558_1 Bacterial membrane protein, YfhO - - - 0.00006425 56.0
HFD2_k127_8534558_2 Transcriptional regulator K06921 - - 0.00006543 49.0
HFD2_k127_8587197_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 427.0
HFD2_k127_8587197_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000000007147 203.0
HFD2_k127_8587197_2 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000003521 138.0
HFD2_k127_868384_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 409.0
HFD2_k127_868384_1 amino acid K03294,K13868 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 362.0
HFD2_k127_868384_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 302.0
HFD2_k127_868384_3 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001011 269.0
HFD2_k127_868384_4 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000000001248 160.0
HFD2_k127_868384_5 Evidence 5 No homology to any previously reported sequences - - - 0.0000002532 59.0
HFD2_k127_86924_0 Peptidase family M3 K01284 - 3.4.15.5 0.0 1057.0
HFD2_k127_86924_1 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005293 268.0
HFD2_k127_86924_4 Virulence factor - - - 0.0001146 49.0
HFD2_k127_871041_0 PFAM Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 352.0
HFD2_k127_871041_1 Bacterial regulatory protein, Fis family K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 327.0
HFD2_k127_871041_2 dead DEAH box helicase - - - 0.0000000000000000000000000000000000000000000000000000000000001088 222.0
HFD2_k127_871041_3 RF-1 domain K15034 - - 0.0000000000000000000000000000000000000000000003376 172.0
HFD2_k127_871041_4 - - - - 0.00000000000000000004218 91.0
HFD2_k127_871041_5 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.00000005811 65.0
HFD2_k127_871041_6 - - - - 0.00003537 56.0
HFD2_k127_871267_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 1.114e-217 691.0
HFD2_k127_871267_1 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009751 520.0
HFD2_k127_871267_10 Protein of unknown function (DUF507) K09804 - - 0.0000005779 55.0
HFD2_k127_871267_11 Tetratricopeptide repeat - - - 0.00004105 55.0
HFD2_k127_871267_12 Helix-turn-helix domain K07729 - - 0.00005015 54.0
HFD2_k127_871267_13 AntiSigma factor - - - 0.00008225 54.0
HFD2_k127_871267_2 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 480.0
HFD2_k127_871267_3 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 331.0
HFD2_k127_871267_4 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001198 294.0
HFD2_k127_871267_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000006816 196.0
HFD2_k127_871267_6 cellulase activity K03296,K22349 - 1.16.3.3 0.000000000000000002799 92.0
HFD2_k127_871267_7 Protein of unknown function (DUF507) K09804 - - 0.000000000000001105 79.0
HFD2_k127_871267_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03116 - - 0.00000000000479 67.0
HFD2_k127_871267_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0001101,GO:0001666,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0036293,GO:0042221,GO:0044419,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051704,GO:0060255,GO:0065007,GO:0070482,GO:0080090,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.000000005486 64.0
HFD2_k127_8713458_0 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000874 373.0
HFD2_k127_8713458_1 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001707 285.0
HFD2_k127_8713458_2 Belongs to the glycosyl hydrolase family 6 K19668 - 3.2.1.91 0.0000007896 63.0
HFD2_k127_8754284_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009437 462.0
HFD2_k127_8754284_1 Asparaginase K01444 - 3.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 313.0
HFD2_k127_886679_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 535.0
HFD2_k127_889256_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 534.0
HFD2_k127_889256_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 438.0
HFD2_k127_889256_10 Acetyltransferase (GNAT) domain - - - 0.000000000000649 68.0
HFD2_k127_889256_11 PFAM Tetratricopeptide repeat - - - 0.00004906 55.0
HFD2_k127_889256_12 Serine threonine protein kinase - - - 0.000776 48.0
HFD2_k127_889256_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 447.0
HFD2_k127_889256_3 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000005571 274.0
HFD2_k127_889256_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000001519 239.0
HFD2_k127_889256_5 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000002603 250.0
HFD2_k127_889256_6 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000004087 243.0
HFD2_k127_889256_7 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000005895 218.0
HFD2_k127_889256_8 glycosyl transferase family 39 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000009078 190.0
HFD2_k127_889256_9 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000006288 181.0
HFD2_k127_923251_0 neurotransmitter:sodium symporter activity K03308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 589.0
HFD2_k127_923251_1 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 531.0
HFD2_k127_923251_2 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 402.0
HFD2_k127_923251_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000008894 262.0
HFD2_k127_923251_4 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006545 273.0
HFD2_k127_923251_5 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000001418 246.0
HFD2_k127_923251_6 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000756 169.0
HFD2_k127_923251_7 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000007706 122.0
HFD2_k127_923251_8 Domain of unknown function (DUF4388) - - - 0.0000000000000000002372 101.0
HFD2_k127_923251_9 PFAM Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.0002643 43.0
HFD2_k127_963377_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 368.0
HFD2_k127_987380_0 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006744 585.0
HFD2_k127_987380_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007254 472.0
HFD2_k127_987380_2 Belongs to the aldehyde dehydrogenase family K22187 - - 0.000000005053 57.0