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Overview

ID MAG01636
Name HFD2_bin.23
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Bacteroidota_A
Class UBA10030
Order UBA10030
Family SZUA-254
Genus
Species
Assembly information
Completeness (%) 75.71
Contamination (%) 2.08
GC content (%) 63.0
N50 (bp) 11,608
Genome size (bp) 2,566,259

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2193

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_1010166_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005573 542.0
HFD2_k127_1010166_1 lipopolysaccharide transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 553.0
HFD2_k127_1010166_2 atpase related to the helicase subunit of the holliday junction resolvase K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 463.0
HFD2_k127_1010166_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 295.0
HFD2_k127_1010166_4 ROK family K00845 GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 295.0
HFD2_k127_1010166_5 peptidyl-prolyl cis-trans isomerase activity K03545 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000002414 228.0
HFD2_k127_1010166_6 cell cycle K05589,K12065,K13052 - - 0.000001468 55.0
HFD2_k127_1056068_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 523.0
HFD2_k127_1056068_1 oxidoreductase activity K00274 - 1.4.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 344.0
HFD2_k127_1056068_2 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.000000000000000000000000000000000000000000000000000000000000000000000000000004041 270.0
HFD2_k127_1056068_3 Poly-gamma-glutamate hydrolase - - - 0.00000000000000000000004519 115.0
HFD2_k127_1067440_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K13482 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 458.0
HFD2_k127_1067440_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 431.0
HFD2_k127_1067440_2 COG4630 Xanthine dehydrogenase iron-sulfur cluster and FAD-binding subunit A K13481 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 385.0
HFD2_k127_1067440_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 332.0
HFD2_k127_1067440_4 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000134 139.0
HFD2_k127_1067440_5 phosphorelay signal transduction system - - - 0.000000000000000001382 99.0
HFD2_k127_1076531_0 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001634 264.0
HFD2_k127_1076531_1 spore germination K07790 - - 0.0000000000000000000000000000000000000000000000000000000000000000001631 242.0
HFD2_k127_1076531_2 Glyoxalase-like domain K05606 GO:0003674,GO:0003824,GO:0004493,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016854,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046491,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 5.1.99.1 0.000000000000000000000000004467 113.0
HFD2_k127_1131734_0 Protein tyrosine kinase - - - 0.0 1066.0
HFD2_k127_1131734_1 Protein tyrosine kinase - - - 1.215e-315 996.0
HFD2_k127_1131734_10 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 546.0
HFD2_k127_1131734_11 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 517.0
HFD2_k127_1131734_12 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 513.0
HFD2_k127_1131734_13 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000874 510.0
HFD2_k127_1131734_14 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441,K10545,K10548 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 505.0
HFD2_k127_1131734_15 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 503.0
HFD2_k127_1131734_16 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 496.0
HFD2_k127_1131734_17 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 495.0
HFD2_k127_1131734_18 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 480.0
HFD2_k127_1131734_19 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 481.0
HFD2_k127_1131734_2 serine-type exopeptidase activity K01322 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 1.651e-313 974.0
HFD2_k127_1131734_20 SMART PDZ DHR GLGF domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 463.0
HFD2_k127_1131734_21 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 458.0
HFD2_k127_1131734_22 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007569 451.0
HFD2_k127_1131734_23 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 419.0
HFD2_k127_1131734_24 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 383.0
HFD2_k127_1131734_25 transcription factor binding K02584,K11914 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 380.0
HFD2_k127_1131734_26 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 341.0
HFD2_k127_1131734_27 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 319.0
HFD2_k127_1131734_28 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 318.0
HFD2_k127_1131734_29 PFAM periplasmic binding protein LacI transcriptional regulator K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 293.0
HFD2_k127_1131734_3 Amino acid permease - - - 2.543e-247 782.0
HFD2_k127_1131734_30 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002898 284.0
HFD2_k127_1131734_31 Branched-chain amino acid transport system / permease component K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000177 267.0
HFD2_k127_1131734_32 ABC-type sugar transport system periplasmic component K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006205 265.0
HFD2_k127_1131734_33 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007916 267.0
HFD2_k127_1131734_34 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002728 281.0
HFD2_k127_1131734_35 Histidine kinase-like ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000007283 243.0
HFD2_k127_1131734_36 Melibiase K07407 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000005537 246.0
HFD2_k127_1131734_37 ATPase associated with various cellular activities, AAA_5 K03696 - - 0.0000000000000000000000000000000000000000000000000000000000001408 216.0
HFD2_k127_1131734_38 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000008915 209.0
HFD2_k127_1131734_39 Metalloenzyme superfamily - - - 0.0000000000000000000000000000000000000000000000001368 195.0
HFD2_k127_1131734_4 Glycoside hydrolase family 38 central region K01191 - 3.2.1.24 4.48e-229 747.0
HFD2_k127_1131734_40 CotH kinase protein K06330 - - 0.0000000000000000000000000000000000000000001075 184.0
HFD2_k127_1131734_41 Putative zinc-binding metallo-peptidase - - - 0.00000000000000000000000000000000000000004394 165.0
HFD2_k127_1131734_42 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000002774 139.0
HFD2_k127_1131734_43 beta-galactosidase activity - - - 0.00000000000000000000000000001701 138.0
HFD2_k127_1131734_44 cellulose binding - - - 0.000000000000000000000000003901 130.0
HFD2_k127_1131734_5 Serine threonine protein kinase K12132 - 2.7.11.1 1.424e-212 683.0
HFD2_k127_1131734_6 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 623.0
HFD2_k127_1131734_7 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 602.0
HFD2_k127_1131734_8 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007915 591.0
HFD2_k127_1131734_9 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 580.0
HFD2_k127_1134305_0 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 474.0
HFD2_k127_1134305_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000001617 143.0
HFD2_k127_1134305_2 HEAT repeats - - - 0.00000000000000000000000003818 119.0
HFD2_k127_1134305_3 - - - - 0.0000000000000000007344 99.0
HFD2_k127_1143728_0 isoleucyl-tRNA aminoacylation K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1272.0
HFD2_k127_1143728_1 membrane organization K03641,K07277 - - 0.0 1032.0
HFD2_k127_1143728_10 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000001378 165.0
HFD2_k127_1143728_11 zinc ion binding K06204 - - 0.00000000000000000000000000000000000002086 150.0
HFD2_k127_1143728_12 Protein of unknown function (DUF2905) - - - 0.00000000000000004665 87.0
HFD2_k127_1143728_13 PFAM DivIVA family protein K04074 - - 0.000000006457 64.0
HFD2_k127_1143728_2 purine-nucleoside phosphorylase activity K03783 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 375.0
HFD2_k127_1143728_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004983 365.0
HFD2_k127_1143728_4 TIGRFAM TIGR00268 family protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 288.0
HFD2_k127_1143728_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 297.0
HFD2_k127_1143728_6 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001455 295.0
HFD2_k127_1143728_7 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008099 279.0
HFD2_k127_1143728_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000000000000000004229 221.0
HFD2_k127_1143728_9 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000001896 216.0
HFD2_k127_1210046_0 phosphoglycerate kinase activity K00927,K01803 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 494.0
HFD2_k127_1210046_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009828 460.0
HFD2_k127_1210046_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 425.0
HFD2_k127_1210046_3 proteolysis - - - 0.00000000000000000000000000000000000000000000000000000000000000007059 232.0
HFD2_k127_1210046_4 Phosphoribosyl transferase domain - - - 0.0000000000001226 74.0
HFD2_k127_1217076_0 Belongs to the peptidase S8 family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 556.0
HFD2_k127_1217076_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000002147 196.0
HFD2_k127_1217076_2 antisigma factor binding K04749 - - 0.00000000000000000001284 95.0
HFD2_k127_1217076_3 - - - - 0.000000000000000000815 91.0
HFD2_k127_1217076_4 Pfam Glycosyl transferase family 2 - - - 0.0000000000003813 75.0
HFD2_k127_1217076_6 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00004881 55.0
HFD2_k127_1217651_0 response to heat K03694,K03695 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030312,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0040007,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 2e-323 1002.0
HFD2_k127_1217651_1 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008426 601.0
HFD2_k127_1217651_2 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 291.0
HFD2_k127_1217651_3 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000005011 133.0
HFD2_k127_1225588_0 peptidase activity, acting on L-amino acid peptides K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 557.0
HFD2_k127_1225588_1 phosphoglucosamine mutase activity K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 473.0
HFD2_k127_1225588_10 Ethanolamine utilisation protein EutN/carboxysome K04028 - - 0.000000000000001215 86.0
HFD2_k127_1225588_2 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 475.0
HFD2_k127_1225588_3 regulation of microtubule-based process K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006084 265.0
HFD2_k127_1225588_4 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001756 267.0
HFD2_k127_1225588_5 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000005718 236.0
HFD2_k127_1225588_6 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000000000000001561 184.0
HFD2_k127_1225588_7 metal cluster binding - - - 0.00000000000000000000000000000000000000001049 166.0
HFD2_k127_1225588_8 Rossmann-like domain - - - 0.000000000000000000000000000000000000004085 158.0
HFD2_k127_1225588_9 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000002246 82.0
HFD2_k127_1255994_0 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 296.0
HFD2_k127_1255994_1 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004511 251.0
HFD2_k127_1255994_2 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000002177 210.0
HFD2_k127_1255994_3 - - - - 0.0000000000000000000000000000000000000000009792 164.0
HFD2_k127_1255994_4 methyltransferase activity K21310 - 2.1.1.334 0.00000000000000000000000002602 111.0
HFD2_k127_1255994_5 pyrroloquinoline quinone binding - - - 0.0000006355 52.0
HFD2_k127_1299815_0 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 517.0
HFD2_k127_1299815_1 Glycosyl hydrolase family 20, catalytic domain K12373 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 500.0
HFD2_k127_1299815_2 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 349.0
HFD2_k127_1299815_3 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008563 290.0
HFD2_k127_1299815_4 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003092 263.0
HFD2_k127_1351449_0 acyl-CoA dehydrogenase activity K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 5.523e-205 645.0
HFD2_k127_1351449_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 394.0
HFD2_k127_1351449_2 phosphorelay signal transduction system K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001773 248.0
HFD2_k127_1375406_0 urocanate hydratase activity K01712 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 4.428e-281 872.0
HFD2_k127_1375406_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.328e-215 700.0
HFD2_k127_1375406_10 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000003983 142.0
HFD2_k127_1375406_11 Ribonuclease UK114-like K09022 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005773,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009579,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0016053,GO:0016787,GO:0019239,GO:0019752,GO:0031967,GO:0031975,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046686,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.5.99.10 0.000000000000000000000000000002334 126.0
HFD2_k127_1375406_12 Cold shock protein domain K03704 - - 0.00000000000000000000000002594 110.0
HFD2_k127_1375406_13 PFAM Cold-shock K03704 - - 0.00000000000003303 75.0
HFD2_k127_1375406_2 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 568.0
HFD2_k127_1375406_3 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 406.0
HFD2_k127_1375406_4 Formiminotransferase-cyclodeaminase K00603,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 389.0
HFD2_k127_1375406_5 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000000012 241.0
HFD2_k127_1375406_6 membrane organization - - - 0.000000000000000000000000000000000000000000000000000000000000003755 234.0
HFD2_k127_1375406_7 Formiminotransferase-cyclodeaminase - - - 0.00000000000000000000000000000000000000000000000192 181.0
HFD2_k127_1375406_8 cell adhesion involved in biofilm formation K20276 - - 0.00000000000000000000000000000000000000000000000518 188.0
HFD2_k127_1375406_9 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000003481 170.0
HFD2_k127_1387690_0 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009976 446.0
HFD2_k127_1387690_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000002245 224.0
HFD2_k127_1389391_0 Amylo-alpha-1,6-glucosidase - - - 3.399e-199 651.0
HFD2_k127_1389391_1 alpha,alpha-trehalase activity K01194,K03931 GO:0003674,GO:0003824,GO:0004553,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015926,GO:0016787,GO:0016798,GO:0033554,GO:0050896,GO:0051716 3.2.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 355.0
HFD2_k127_1389391_2 PFAM binding-protein-dependent transport systems inner membrane component K02025,K17242 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006887 306.0
HFD2_k127_1389391_3 glycerophosphodiester transmembrane transport K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002727 278.0
HFD2_k127_1389391_4 galactokinase activity K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000005141 235.0
HFD2_k127_1389391_5 DinB family - - - 0.0000000000000000000000000000000000004396 145.0
HFD2_k127_1389391_6 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.0000000002348 72.0
HFD2_k127_1469381_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.0 1396.0
HFD2_k127_1469381_1 Domain of unknown function (DUF5110) K01187 - 3.2.1.20 1.96e-216 703.0
HFD2_k127_1469381_10 DsrE/DsrF-like family - - - 0.0000000000000000000000000001266 125.0
HFD2_k127_1469381_11 transferase activity, transferring acyl groups K15520 - 2.3.1.189 0.00000000000000000000000001607 115.0
HFD2_k127_1469381_12 TonB-dependent receptor K01179 - 3.2.1.4 0.0000000000000000000000002701 121.0
HFD2_k127_1469381_2 Cys/Met metabolism PLP-dependent enzyme K01761 - 4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 520.0
HFD2_k127_1469381_3 enterobactin catabolic process K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 517.0
HFD2_k127_1469381_4 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 360.0
HFD2_k127_1469381_5 Aldo Keto reductase K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 351.0
HFD2_k127_1469381_6 epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 294.0
HFD2_k127_1469381_7 - - - - 0.00000000000000000000000000000000000000004763 158.0
HFD2_k127_1469381_8 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000199 154.0
HFD2_k127_1469381_9 Phosphate acyltransferases - - - 0.000000000000000000000000000004474 136.0
HFD2_k127_1513344_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 6.773e-219 690.0
HFD2_k127_1513344_1 drug transmembrane transporter activity K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 447.0
HFD2_k127_1513344_10 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000001693 180.0
HFD2_k127_1513344_11 protein trimerization - - - 0.0000000000000000000000000000000000000000000005399 175.0
HFD2_k127_1513344_12 STAS domain K04749 - - 0.000000000000000000000000000000000000007054 151.0
HFD2_k127_1513344_13 sigma factor antagonist activity K04757 - 2.7.11.1 0.000000000000000000000000000001273 126.0
HFD2_k127_1513344_14 - - - - 0.00000000000000000000006356 100.0
HFD2_k127_1513344_15 DNA polymerase K02347 - - 0.0000000000000000004564 87.0
HFD2_k127_1513344_16 Cell wall-active antibiotics response 4TMS YvqF K11622 - - 0.0000001736 60.0
HFD2_k127_1513344_2 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 452.0
HFD2_k127_1513344_3 PFAM Stage II sporulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 370.0
HFD2_k127_1513344_4 Metallo-beta-lactamase superfamily K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 327.0
HFD2_k127_1513344_5 Metalloenzyme superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003775 274.0
HFD2_k127_1513344_6 Glycosyl transferase, family 9 K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006521 276.0
HFD2_k127_1513344_7 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000002909 242.0
HFD2_k127_1513344_8 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000994 237.0
HFD2_k127_1513344_9 Kdo2-lipid A biosynthetic process K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000001818 208.0
HFD2_k127_1559868_0 polyribonucleotide nucleotidyltransferase activity K02945,K03527,K07571,K12132 GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 1.17.7.4,2.7.11.1 4.483e-254 798.0
HFD2_k127_1559868_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K18707 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 454.0
HFD2_k127_1559868_2 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009113 372.0
HFD2_k127_1559868_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000002519 214.0
HFD2_k127_1559868_4 Glycosyl transferase, family 2 K07011 - - 0.0000000000000000000000000000000000000000000000003992 186.0
HFD2_k127_1559868_5 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000008155 149.0
HFD2_k127_1559868_6 - - - - 0.000000000000000000000000000000000155 141.0
HFD2_k127_1559868_7 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000523 113.0
HFD2_k127_1564477_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 408.0
HFD2_k127_1564477_1 PhoQ Sensor K01768,K04769,K10914 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005233 296.0
HFD2_k127_1564477_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005178 262.0
HFD2_k127_1564477_3 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000001314 249.0
HFD2_k127_1564477_4 PFAM GDSL-like Lipase Acylhydrolase - - - 0.00000000000000000000000000000000000000000003489 166.0
HFD2_k127_1564477_5 Transcriptional regulator, Crp Fnr family K10914 - - 0.000000000000000009678 97.0
HFD2_k127_1564477_6 Putative zinc-finger - - - 0.0000001139 62.0
HFD2_k127_1564477_7 Protein of unknown function (DUF1460) - - - 0.000003882 59.0
HFD2_k127_1574127_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1315.0
HFD2_k127_1574127_1 glucosamine-6-phosphate deaminase activity K01057,K02564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.1.1.31,3.5.99.6 4.772e-268 846.0
HFD2_k127_1574127_10 Planctomycete cytochrome C - - - 0.0005482 53.0
HFD2_k127_1574127_2 Glycoside hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 632.0
HFD2_k127_1574127_3 Trehalase K01194 - 3.2.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 616.0
HFD2_k127_1574127_4 PFAM peptidase T2 asparaginase 2 K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000619 338.0
HFD2_k127_1574127_5 Molybdenum Cofactor Synthesis C K20967 - 4.1.99.22,4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007263 293.0
HFD2_k127_1574127_6 Participates in the control of copper homeostasis K06201 - - 0.0000000000000000000000000000000000000000000000000000001426 209.0
HFD2_k127_1574127_7 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000001356 186.0
HFD2_k127_1574127_8 beta-N-acetylhexosaminidase activity K12373 - 3.2.1.52 0.0000000000000000000000000000000000005311 143.0
HFD2_k127_1574127_9 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000002792 112.0
HFD2_k127_1597690_0 calcium- and calmodulin-responsive adenylate cyclase activity K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007721 476.0
HFD2_k127_1597690_1 cellulose binding - - - 0.0000000000000000000000000000000000000000000000001346 203.0
HFD2_k127_1597690_2 Sulfatase-modifying factor enzyme 1 K01176,K01206,K01218,K01219,K01224 - 3.2.1.1,3.2.1.51,3.2.1.78,3.2.1.81,3.2.1.89 0.0000000000000000000000000000000000000000000000005444 201.0
HFD2_k127_1597690_3 Sulfatase-modifying factor enzyme 1 K01176,K01206,K01218,K01219,K01224 - 3.2.1.1,3.2.1.51,3.2.1.78,3.2.1.81,3.2.1.89 0.0000000000000000000000000000000000000000000001632 195.0
HFD2_k127_1597690_4 N-Acetylmuramoyl-L-alanine amidase K01176,K01448 GO:0003674,GO:0005198,GO:0005199,GO:0005575,GO:0005623,GO:0008150,GO:0009273,GO:0009987,GO:0030115,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071840,GO:0071944 3.2.1.1,3.5.1.28 0.0000000000000000007539 88.0
HFD2_k127_1612926_0 Peptidase, M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 476.0
HFD2_k127_1612926_1 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000001236 230.0
HFD2_k127_1612926_2 Peptidase, M16 K07263 - - 0.0000000000000000000000000000000007626 133.0
HFD2_k127_1649585_0 Glycosyl hydrolase family 47 K01230,K10085 - 3.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 505.0
HFD2_k127_1649585_1 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 370.0
HFD2_k127_1649585_10 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00001564 56.0
HFD2_k127_1649585_2 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 308.0
HFD2_k127_1649585_3 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000001841 221.0
HFD2_k127_1649585_4 Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000001568 214.0
HFD2_k127_1649585_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000002161 224.0
HFD2_k127_1649585_6 MASE1 - - - 0.0000000000000000000000000000000000000000000000000000000009581 216.0
HFD2_k127_1649585_7 cellulose binding - - - 0.000000000000000000000000000000000000000000000000001113 212.0
HFD2_k127_1649585_8 Sulfatase-modifying factor enzyme 1 K01176,K01206,K01218,K01219,K01224 - 3.2.1.1,3.2.1.51,3.2.1.78,3.2.1.81,3.2.1.89 0.0000000000000000000000000000000000001967 165.0
HFD2_k127_1649585_9 Photosynthesis system II assembly factor YCF48 - - - 0.000000001035 73.0
HFD2_k127_169107_0 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 426.0
HFD2_k127_169107_1 Transferase K02527,K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33,2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 389.0
HFD2_k127_169107_10 Cysteine-rich CPXCG - - - 0.00000000000001533 76.0
HFD2_k127_169107_12 - - - - 0.000005754 49.0
HFD2_k127_169107_13 - - - - 0.00005127 46.0
HFD2_k127_169107_2 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K06898,K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009364 329.0
HFD2_k127_169107_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 302.0
HFD2_k127_169107_4 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001967 253.0
HFD2_k127_169107_5 Belongs to the pseudouridine synthase RsuA family K06181 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20 0.00000000000000000000000000000000000000000000000000000000307 210.0
HFD2_k127_169107_6 Cytochrome c biogenesis protein - - - 0.0000000000000000000000000000000000000177 151.0
HFD2_k127_169107_7 Protein of unknown function (DUF1572) - - - 0.0000000000000000000000000000001134 130.0
HFD2_k127_169107_8 PFAM MOSC domain - - - 0.000000000000000000000000000009143 123.0
HFD2_k127_169107_9 Thioredoxin-like - - - 0.000000000000000000000000004915 115.0
HFD2_k127_1693579_0 TonB-dependent receptor - - - 0.0 1047.0
HFD2_k127_1693579_1 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 6.475e-233 741.0
HFD2_k127_1693579_10 cobalamin binding K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000002259 216.0
HFD2_k127_1693579_11 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000000000005316 213.0
HFD2_k127_1693579_12 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000002132 194.0
HFD2_k127_1693579_13 Sulfatase-modifying factor enzyme 1 K01176,K01206,K01218,K01219,K01224 - 3.2.1.1,3.2.1.51,3.2.1.78,3.2.1.81,3.2.1.89 0.000000000000000000000000000000003395 150.0
HFD2_k127_1693579_14 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000000001447 131.0
HFD2_k127_1693579_15 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000001647 120.0
HFD2_k127_1693579_16 amine dehydrogenase activity - - - 0.00000000000000000001616 97.0
HFD2_k127_1693579_17 Domain of unknown function (DU1801) K00784 - 3.1.26.11 0.0000000000000000001012 93.0
HFD2_k127_1693579_18 Belongs to the peptidase S8 family K01337,K01387,K05994,K08604,K14645,K20276 - 3.4.11.10,3.4.21.50,3.4.24.25,3.4.24.3 0.0000000000000001159 96.0
HFD2_k127_1693579_19 PFAM Radical SAM domain protein K22227 - - 0.000000000000007792 87.0
HFD2_k127_1693579_2 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 1.263e-205 661.0
HFD2_k127_1693579_20 iron ion homeostasis K04758 - - 0.00000000000008181 74.0
HFD2_k127_1693579_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 609.0
HFD2_k127_1693579_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006685 578.0
HFD2_k127_1693579_5 PFAM DNA polymerase B, exonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007689 496.0
HFD2_k127_1693579_6 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 413.0
HFD2_k127_1693579_7 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175,K00187 - 1.2.7.11,1.2.7.3,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000391 385.0
HFD2_k127_1693579_8 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00177,K00187 - 1.2.7.3,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000001781 230.0
HFD2_k127_1693579_9 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000114 240.0
HFD2_k127_1727529_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 568.0
HFD2_k127_1727529_1 KR domain - - - 0.0000000000000000000000000000000000003734 149.0
HFD2_k127_1727529_2 PFAM Yqey-like protein K09117 - - 0.0000000000000000000000000000000001465 142.0
HFD2_k127_1727529_3 Biotin carboxylase K11263 - 6.3.4.14,6.4.1.2,6.4.1.3 0.0000000000000000000000000000001024 129.0
HFD2_k127_1727529_4 Zinc-uptake complex component A periplasmic K09815 - - 0.00000000000000000000000002432 115.0
HFD2_k127_1727529_5 - - - - 0.00000000000000000000387 107.0
HFD2_k127_1727529_6 toxin biosynthetic process K03558 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 - 0.000000000000001683 86.0
HFD2_k127_1730342_0 symporter activity K03307 - - 5.99e-233 736.0
HFD2_k127_1730342_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972,K10754 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 6.318e-204 657.0
HFD2_k127_1730342_10 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008525 300.0
HFD2_k127_1730342_11 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003824 282.0
HFD2_k127_1730342_12 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000001657 212.0
HFD2_k127_1730342_13 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000007774 203.0
HFD2_k127_1730342_14 pfam abc K01990 - - 0.00000000000000000000000000000000000000000000000000002867 205.0
HFD2_k127_1730342_15 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000000002402 180.0
HFD2_k127_1730342_16 cell redox homeostasis - - - 0.000000000000000000000002373 113.0
HFD2_k127_1730342_17 antisigma factor binding K04749 - - 0.000000000000000026 86.0
HFD2_k127_1730342_18 Helix-turn-helix domain K15539 - - 0.00000000001469 74.0
HFD2_k127_1730342_2 Methylenetetrahydrofolate reductase K00297,K00547,K00548 - 1.5.1.20,2.1.1.10,2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 548.0
HFD2_k127_1730342_3 Aldo/keto reductase family K05882 - 1.1.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 494.0
HFD2_k127_1730342_4 7TM receptor with intracellular HD hydrolase K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 507.0
HFD2_k127_1730342_5 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 437.0
HFD2_k127_1730342_6 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 418.0
HFD2_k127_1730342_7 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 423.0
HFD2_k127_1730342_8 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 393.0
HFD2_k127_1730342_9 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 373.0
HFD2_k127_1739492_0 CoA carboxylase activity K01966 - 2.1.3.15,6.4.1.3 2.215e-209 661.0
HFD2_k127_1739492_1 acyl-CoA dehydrogenase activity K00248,K11410,K18244 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 464.0
HFD2_k127_1765044_0 Amidohydrolase family K01443 - 3.5.1.25 6.37e-318 1002.0
HFD2_k127_1765044_1 nucleic acid phosphodiester bond hydrolysis K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005334 531.0
HFD2_k127_1765044_10 metal cluster binding K06940,K18475 - - 0.0000000000000000000000000000008387 129.0
HFD2_k127_1765044_11 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000001984 121.0
HFD2_k127_1765044_12 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K04757 - 2.7.11.1 0.000000000000000000000000002341 116.0
HFD2_k127_1765044_13 Transcriptional regulatory protein, C terminal K07657 - - 0.0000000674 61.0
HFD2_k127_1765044_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 442.0
HFD2_k127_1765044_3 imidazolonepropionase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009911 433.0
HFD2_k127_1765044_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000004466 237.0
HFD2_k127_1765044_5 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000003394 183.0
HFD2_k127_1765044_6 lipopolysaccharide metabolic process K08309,K19804 - - 0.000000000000000000000000000000000000000004257 173.0
HFD2_k127_1765044_7 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000398 162.0
HFD2_k127_1765044_8 cell adhesion involved in biofilm formation K20276 - - 0.00000000000000000000000000000000000001724 156.0
HFD2_k127_1765044_9 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000000000002184 127.0
HFD2_k127_1767883_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 6.604e-204 647.0
HFD2_k127_1767883_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595,K06883 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 309.0
HFD2_k127_1767883_2 - - - - 0.0000002232 55.0
HFD2_k127_1788691_0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 480.0
HFD2_k127_1788691_1 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 290.0
HFD2_k127_1791152_0 1-deoxy-D-xylulose-5-phosphate synthase activity K01662 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 9.945e-275 861.0
HFD2_k127_1791152_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601,K03797 - 3.1.11.6,3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 380.0
HFD2_k127_1791152_10 Heavy-metal-associated domain - - - 0.0000000002389 66.0
HFD2_k127_1791152_11 PFAM Cytochrome c assembly protein K02198 - - 0.0006272 49.0
HFD2_k127_1791152_2 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 348.0
HFD2_k127_1791152_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 325.0
HFD2_k127_1791152_4 PFAM GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000000000000000000000000002073 237.0
HFD2_k127_1791152_5 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000009389 208.0
HFD2_k127_1791152_6 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000003151 188.0
HFD2_k127_1791152_7 Predicted membrane protein (DUF2318) K09005 - - 0.000000000000000000000000000000000003386 145.0
HFD2_k127_1791152_8 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000004328 120.0
HFD2_k127_1791152_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000002059 73.0
HFD2_k127_1805992_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 4.41e-246 779.0
HFD2_k127_1805992_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 300.0
HFD2_k127_1805992_2 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000002025 249.0
HFD2_k127_1852429_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 594.0
HFD2_k127_1852429_1 Chase2 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 430.0
HFD2_k127_1852429_10 - - - - 0.00000000000000000000001879 108.0
HFD2_k127_1852429_11 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000009884 105.0
HFD2_k127_1852429_12 Outer membrane lipoprotein - - - 0.00000000000000000000168 102.0
HFD2_k127_1852429_15 - - - - 0.000000000003055 76.0
HFD2_k127_1852429_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 334.0
HFD2_k127_1852429_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002961 256.0
HFD2_k127_1852429_4 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000001612 234.0
HFD2_k127_1852429_5 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000002179 230.0
HFD2_k127_1852429_6 4-hydroxybenzoate polyprenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000004288 201.0
HFD2_k127_1852429_7 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000002243 181.0
HFD2_k127_1852429_8 Domain of unknown function (DUF4382) - - - 0.0000000000000000000000000000000000000009225 161.0
HFD2_k127_1852429_9 Tetratricopeptide repeat - - - 0.00000000000000000000000000002207 133.0
HFD2_k127_1876819_0 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 469.0
HFD2_k127_1876819_1 N-acetylmuramoyl-L-alanine amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000001205 237.0
HFD2_k127_1876819_2 TonB-dependent Receptor Plug Domain - - - 0.00000000000000000000000000000000000000000000000000000001244 224.0
HFD2_k127_1876819_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 0.0000000000000000000000000103 123.0
HFD2_k127_1876819_4 FecR protein - - - 0.000000000000000001981 96.0
HFD2_k127_1876819_6 pectinesterase activity K10117 - - 0.0000000000000168 84.0
HFD2_k127_1876819_7 - - - - 0.0000002726 61.0
HFD2_k127_1876819_8 - - - - 0.0000006233 61.0
HFD2_k127_1888047_0 UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity K00790 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 503.0
HFD2_k127_1888047_1 metallopeptidase activity K01179,K01181 - 3.2.1.4,3.2.1.8 0.000000000000000000193 99.0
HFD2_k127_1888047_2 exo-alpha-(2->6)-sialidase activity K01186 - 3.2.1.18 0.00000000000000000337 100.0
HFD2_k127_1888047_3 involved in cell wall biogenesis - - - 0.0000000000001147 75.0
HFD2_k127_1888047_4 protein secretion K13735,K20276 - - 0.0000000003785 70.0
HFD2_k127_1901468_0 membrane organization K03641,K07277 - - 7.324e-307 970.0
HFD2_k127_1901468_1 3-oxoacyl-[acyl-carrier-protein] synthase activity K09458,K14660 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 552.0
HFD2_k127_1901468_10 ribonuclease III activity K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000006237 201.0
HFD2_k127_1901468_11 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000144 204.0
HFD2_k127_1901468_12 asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000005419 208.0
HFD2_k127_1901468_13 - - - - 0.000000000000000000000000000000000000000000000004048 180.0
HFD2_k127_1901468_14 PQQ-like domain - - - 0.000000000000000000000000000000000002121 154.0
HFD2_k127_1901468_15 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000001307 130.0
HFD2_k127_1901468_16 metal-binding, possibly nucleic acid-binding protein K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000001205 122.0
HFD2_k127_1901468_17 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000001134 122.0
HFD2_k127_1901468_18 - - - - 0.000000000000000000000002577 109.0
HFD2_k127_1901468_19 CoA-binding protein K06929 - - 0.00000000000000000000001108 109.0
HFD2_k127_1901468_2 beta-ketoacyl-acyl-carrier-protein synthase III activity K00648 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 455.0
HFD2_k127_1901468_20 Protein of unknown function (DUF3276) - - - 0.0000000000000000000009762 97.0
HFD2_k127_1901468_21 Ribosomal L32p protein family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.000000000000000007452 84.0
HFD2_k127_1901468_23 - - - - 0.00000001039 63.0
HFD2_k127_1901468_24 NlpE N-terminal domain - - - 0.0000006716 54.0
HFD2_k127_1901468_25 cellular alcohol biosynthetic process K02291,K10208 - 2.5.1.32,2.5.1.96,2.5.1.99 0.0007589 51.0
HFD2_k127_1901468_3 [acyl-carrier-protein] S-malonyltransferase activity K00645,K15327,K15329,K15355,K15469 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 344.0
HFD2_k127_1901468_4 fatty acid biosynthetic process K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 346.0
HFD2_k127_1901468_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 357.0
HFD2_k127_1901468_6 Bacterial phospho-glucose isomerase C-terminal SIS domain K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 334.0
HFD2_k127_1901468_7 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001202 286.0
HFD2_k127_1901468_8 TIGRFAM 3-oxoacyl-(acyl-carrier-protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009399 276.0
HFD2_k127_1901468_9 cyclic nucleotide binding K01420,K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002944 269.0
HFD2_k127_1907087_0 peptidyl-prolyl cis-trans isomerase activity K01802,K03769,K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 466.0
HFD2_k127_1907087_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 441.0
HFD2_k127_1907087_2 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 446.0
HFD2_k127_1907087_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000006431 174.0
HFD2_k127_1907087_4 antisigma factor binding K04749 - - 0.00000000000000000000000000001785 121.0
HFD2_k127_1907087_5 - - - - 0.00000000000000000000253 102.0
HFD2_k127_1907087_6 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000002925 91.0
HFD2_k127_1939056_0 DNA-templated transcription, termination K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 4.666e-225 702.0
HFD2_k127_1939056_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 378.0
HFD2_k127_1939056_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000001303 118.0
HFD2_k127_1939056_3 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000233 96.0
HFD2_k127_194586_0 phosphorelay signal transduction system - - - 1.948e-224 706.0
HFD2_k127_194586_1 Outer membrane protein beta-barrel domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 597.0
HFD2_k127_194586_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 587.0
HFD2_k127_194586_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 397.0
HFD2_k127_194586_4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01476,K01480 GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 3.5.3.1,3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004999 354.0
HFD2_k127_194586_5 PFAM Peptidase M22, glycoprotease K14742 - - 0.000000000000000000000000000000005572 138.0
HFD2_k127_194586_6 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000004886 139.0
HFD2_k127_194586_7 energy transducer activity K03832,K09992 - - 0.0000000000000000003095 97.0
HFD2_k127_194586_8 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.0001232 53.0
HFD2_k127_2025039_0 formate dehydrogenase - - - 7.194e-276 867.0
HFD2_k127_2025039_1 Prokaryotic cytochrome b561 - - - 6.711e-244 769.0
HFD2_k127_2025039_10 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 367.0
HFD2_k127_2025039_11 Cytochrome c554 and c-prime K03620 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 343.0
HFD2_k127_2025039_12 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000000000000000000000000000000000000000000001852 250.0
HFD2_k127_2025039_13 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.0000000000000000000000000000000000000000000006108 170.0
HFD2_k127_2025039_14 amine dehydrogenase activity K21449 - - 0.0000000000000000000000000000000000000000000009441 173.0
HFD2_k127_2025039_15 - - - - 0.00000000000000000000000008267 116.0
HFD2_k127_2025039_16 Cytochrome c - - - 0.00000000000000000005 101.0
HFD2_k127_2025039_17 antisigma factor binding K04749 - - 0.0009222 42.0
HFD2_k127_2025039_2 lysine biosynthetic process via aminoadipic acid - - - 2.814e-200 647.0
HFD2_k127_2025039_3 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 571.0
HFD2_k127_2025039_4 coproporphyrinogen oxidase activity K02495 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 527.0
HFD2_k127_2025039_5 Cytochrome C assembly protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007815 503.0
HFD2_k127_2025039_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 485.0
HFD2_k127_2025039_7 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007061 471.0
HFD2_k127_2025039_8 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 443.0
HFD2_k127_2025039_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 384.0
HFD2_k127_2059552_0 Pkd domain containing protein - - - 2.526e-242 782.0
HFD2_k127_2059552_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 3.225e-197 634.0
HFD2_k127_2059552_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000004716 54.0
HFD2_k127_2059552_3 Metallo-peptidase family M12B Reprolysin-like - - - 0.0000002759 64.0
HFD2_k127_2109519_0 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 316.0
HFD2_k127_2109519_1 MobA-like NTP transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001175 242.0
HFD2_k127_2109519_2 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000001322 223.0
HFD2_k127_2109519_3 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K17105 - 2.5.1.39,2.5.1.42 0.0000000000000000000000000000000000000000000001344 184.0
HFD2_k127_2109519_4 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000003013 140.0
HFD2_k127_2109519_5 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000004065 134.0
HFD2_k127_2109519_6 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000002621 128.0
HFD2_k127_2109519_7 thiamine-phosphate kinase activity K00946 - 2.7.4.16 0.000000000000000000000007245 107.0
HFD2_k127_2109519_8 Protein of unknown function (DUF1579) - - - 0.00000000000000000359 92.0
HFD2_k127_2109519_9 nucleotide catabolic process K01181,K07004 - 3.2.1.8 0.00000000000001112 88.0
HFD2_k127_2117135_0 glucan 1,4-alpha-glucosidase activity K01178 - 3.2.1.3 1.242e-302 960.0
HFD2_k127_2117135_1 Glycosyltransferase 36 associated - - - 2.603e-254 807.0
HFD2_k127_2117135_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 540.0
HFD2_k127_2117135_4 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 418.0
HFD2_k127_2117135_5 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 336.0
HFD2_k127_2117135_6 kinase activity K02848 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008204 276.0
HFD2_k127_2117135_7 phospholipase Carboxylesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000005833 246.0
HFD2_k127_2140607_0 hydrolase activity, hydrolyzing O-glycosyl compounds K01337 - 3.4.21.50 1.627e-241 782.0
HFD2_k127_2140607_1 Carbamoyltransferase C-terminus K00612 - - 1.19e-227 720.0
HFD2_k127_2140607_10 Binding-protein-dependent transport system inner membrane component K15772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 321.0
HFD2_k127_2140607_11 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001507 281.0
HFD2_k127_2140607_12 chaperone-mediated protein folding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005039 289.0
HFD2_k127_2140607_13 chaperone-mediated protein folding K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000145 274.0
HFD2_k127_2140607_14 Calcineurin-like phosphoesterase K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000003713 247.0
HFD2_k127_2140607_15 SMART von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000168 223.0
HFD2_k127_2140607_16 enterobactin catabolic process K07214 - - 0.0000000000000000000000000000000000000000000000000000000008259 218.0
HFD2_k127_2140607_17 transcription antitermination K03625 - - 0.000000000000000000000000000000000000000000000202 176.0
HFD2_k127_2140607_18 Outer membrane lipoprotein - - - 0.00000000000000000000000002052 128.0
HFD2_k127_2140607_19 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000003247 110.0
HFD2_k127_2140607_2 serine-type D-Ala-D-Ala carboxypeptidase activity K05366 - 2.4.1.129,3.4.16.4 8.098e-216 692.0
HFD2_k127_2140607_20 PFAM response regulator receiver K07657 - - 0.00000000000000000002448 96.0
HFD2_k127_2140607_21 - - - - 0.0000000000000005103 90.0
HFD2_k127_2140607_22 - - - - 0.0000000000000008983 78.0
HFD2_k127_2140607_23 - - - - 0.000000006811 60.0
HFD2_k127_2140607_3 PFAM alpha amylase, catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 600.0
HFD2_k127_2140607_4 SMART alpha amylase, catalytic sub domain K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 478.0
HFD2_k127_2140607_5 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009174 473.0
HFD2_k127_2140607_6 PFAM major facilitator superfamily MFS_1 K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 413.0
HFD2_k127_2140607_7 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 398.0
HFD2_k127_2140607_8 Sugar ABC transporter permease K10109,K15770,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 374.0
HFD2_k127_2140607_9 maltose binding K15770,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 373.0
HFD2_k127_2146186_0 glucan 1,4-alpha-glucosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001261 296.0
HFD2_k127_2154754_0 lysine biosynthetic process via aminoadipic acid - - - 2.757e-242 772.0
HFD2_k127_2254952_0 aspartate-tRNA(Asn) ligase activity K01876 GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.12 1.596e-252 792.0
HFD2_k127_2254952_1 4-Hydroxyphenylpyruvate dioxygenase - - - 4.513e-201 647.0
HFD2_k127_2254952_2 translation initiation factor activity K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000001771 239.0
HFD2_k127_2257755_0 involved in lipopolysaccharide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 341.0
HFD2_k127_2257755_1 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000005213 87.0
HFD2_k127_2257755_3 cellulose binding - - - 0.0000000001907 70.0
HFD2_k127_2258208_1 TonB-dependent receptor - - - 9.281e-278 879.0
HFD2_k127_2258208_2 cellulose binding K00505 - 1.14.18.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006353 353.0
HFD2_k127_2310756_0 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 7.153e-227 709.0
HFD2_k127_2310756_1 Pirin C-terminal cupin domain K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 533.0
HFD2_k127_2310756_2 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000000000000005895 205.0
HFD2_k127_2310756_3 Cyclic nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000001143 203.0
HFD2_k127_2310756_4 Histidine kinase K01768,K12132 - 2.7.11.1,4.6.1.1 0.00000000000000000000000000000000000004092 151.0
HFD2_k127_2310756_5 bis(5'-adenosyl)-triphosphatase activity K02503 - - 0.000000000000000000000000000000004971 133.0
HFD2_k127_2310756_6 Cold shock protein domain K03704 - - 0.000000000000000000000003024 106.0
HFD2_k127_2310756_7 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000005561 78.0
HFD2_k127_2310756_8 Tetratricopeptide repeat - - - 0.0000005586 62.0
HFD2_k127_2316916_0 DNA topoisomerase II activity K02469 - 5.99.1.3 0.0 1151.0
HFD2_k127_2316916_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.993e-243 769.0
HFD2_k127_2316916_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 458.0
HFD2_k127_2316916_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 353.0
HFD2_k127_2316916_4 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003026 275.0
HFD2_k127_2316916_5 Protein of unknown function (DUF721) - - - 0.00000000000005432 78.0
HFD2_k127_23689_0 Mur ligase middle domain K01932 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 305.0
HFD2_k127_23689_1 - - - - 0.00000000000000000000000000000000000000000000000002087 198.0
HFD2_k127_23689_2 Capsule biosynthesis CapC K22116 - - 0.000000000000000000000000000000000000238 150.0
HFD2_k127_23689_3 cell adhesion involved in biofilm formation K20276 - - 0.000000000000000000005244 102.0
HFD2_k127_2379018_0 tryptophanase activity K01667 - 4.1.99.1 1.15e-226 711.0
HFD2_k127_2379018_1 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 460.0
HFD2_k127_2379018_11 Hemerythrin HHE cation binding domain K09155 - - 0.00000000001205 72.0
HFD2_k127_2379018_2 Periplasmic component of the Tol biopolymer transport system K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 428.0
HFD2_k127_2379018_3 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 342.0
HFD2_k127_2379018_4 Belongs to the enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000004626 240.0
HFD2_k127_2379018_5 purine ribonucleoside salvage K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000003186 222.0
HFD2_k127_2379018_6 peroxiredoxin activity K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000001001 188.0
HFD2_k127_2379018_7 Zincin-like metallopeptidase - - - 0.0000000000000000000000006488 109.0
HFD2_k127_2379018_8 response regulator K03412,K03413 - 3.1.1.61,3.5.1.44 0.00000000000000001581 91.0
HFD2_k127_2409246_0 membrane organization K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 413.0
HFD2_k127_2409246_1 transferase activity, transferring alkyl or aryl (other than methyl) groups K00806,K14215,K21273 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.86,2.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008039 317.0
HFD2_k127_2409246_2 YbaB/EbfC DNA-binding family K09747 - - 0.000000000000000000000000000006006 123.0
HFD2_k127_2409246_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000003409 98.0
HFD2_k127_2413009_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 396.0
HFD2_k127_2413009_1 Sulfatase-modifying factor enzyme 1 K01176,K01206,K01218,K01219,K01224 - 3.2.1.1,3.2.1.51,3.2.1.78,3.2.1.81,3.2.1.89 0.00000000000000000000000000000000000000000000000002729 206.0
HFD2_k127_2413009_2 Photosynthesis system II assembly factor YCF48 - - - 0.0000000000009081 83.0
HFD2_k127_2416799_0 nucleotide-excision repair K03701 - - 0.0 1279.0
HFD2_k127_2416799_1 belongs to the aldehyde dehydrogenase family K00132 - 1.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 577.0
HFD2_k127_2416799_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 448.0
HFD2_k127_2416799_3 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000005819 207.0
HFD2_k127_2416799_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000000000000005537 171.0
HFD2_k127_2416799_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000003409 166.0
HFD2_k127_2416799_6 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000004841 140.0
HFD2_k127_2416799_7 Domain of unknown function (DUF296) K06934 - - 0.0000000000000000000000000000000004522 135.0
HFD2_k127_2416799_8 - - - - 0.0001056 46.0
HFD2_k127_2453380_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 3.729e-245 771.0
HFD2_k127_2453380_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 327.0
HFD2_k127_2453380_2 NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004377 271.0
HFD2_k127_2453380_3 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0046983,GO:0055114 - 0.0000000000000000000000000000000000000000000000002161 190.0
HFD2_k127_2492597_0 Multidrug ABC transporter permease K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009242 397.0
HFD2_k127_2492597_1 nicotinamide-nucleotide amidase activity K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 384.0
HFD2_k127_2492597_2 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 379.0
HFD2_k127_2492597_3 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 332.0
HFD2_k127_2492597_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000001214 227.0
HFD2_k127_2492597_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000008007 172.0
HFD2_k127_2492597_6 - - - - 0.000000000000000000000000000000000000004092 151.0
HFD2_k127_2492597_7 PFAM phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000000000000000003699 143.0
HFD2_k127_2492597_8 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000003317 92.0
HFD2_k127_2495890_0 chorismate synthase activity K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 338.0
HFD2_k127_2495890_1 Prephenate dehydrogenase K00210 - 1.3.1.12 0.0000000000000000000000000000000000000001025 163.0
HFD2_k127_2495890_2 Belongs to the peptidase S8 family - - - 0.0000000000009546 82.0
HFD2_k127_250042_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114 1.2.7.1 2.879e-259 811.0
HFD2_k127_250042_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006579 455.0
HFD2_k127_250042_2 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 442.0
HFD2_k127_250042_3 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000001005 199.0
HFD2_k127_250042_4 glycine decarboxylation via glycine cleavage system K02437 - - 0.00000000000000000000000004469 118.0
HFD2_k127_250042_5 4 iron, 4 sulfur cluster binding K00124 - - 0.00000000000000000000001044 102.0
HFD2_k127_250042_6 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 0.00000006543 57.0
HFD2_k127_250042_7 Glycine cleavage H-protein - - - 0.000002284 59.0
HFD2_k127_2548080_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 309.0
HFD2_k127_2548080_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000001586 224.0
HFD2_k127_2548080_2 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000000005355 109.0
HFD2_k127_2548080_3 TM2 domain - - - 0.0002383 48.0
HFD2_k127_2697617_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 338.0
HFD2_k127_2697617_1 phosphatidylcholine synthase activity K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000004263 220.0
HFD2_k127_2697617_2 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000005349 208.0
HFD2_k127_2697617_3 PFAM SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000004504 153.0
HFD2_k127_2697617_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000007578 132.0
HFD2_k127_2697617_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000008939 105.0
HFD2_k127_2697617_6 protein secretion K03116,K03117 - - 0.00000000000003191 74.0
HFD2_k127_2697617_7 PFAM O-antigen polymerase K18814 - - 0.0005784 51.0
HFD2_k127_2733436_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009885 537.0
HFD2_k127_2733436_1 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001662 280.0
HFD2_k127_2733436_2 ATPase activity K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005732 253.0
HFD2_k127_2733436_3 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000007528 245.0
HFD2_k127_2733436_4 CDP-alcohol phosphatidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000003086 238.0
HFD2_k127_2733436_5 inositol-3-phosphate synthase activity K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000003193 211.0
HFD2_k127_2733436_6 HAD-hyrolase-like K07025 - - 0.000000000000000000000000000000000000000000000004074 192.0
HFD2_k127_2733436_7 PFAM Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000002825 173.0
HFD2_k127_2733436_8 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.00000000000000000001129 93.0
HFD2_k127_2733436_9 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000001469 60.0
HFD2_k127_2735858_0 carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 4.14e-261 813.0
HFD2_k127_2735858_1 LysM domain K08307,K12204 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 496.0
HFD2_k127_2735858_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 390.0
HFD2_k127_2735858_3 Helix-hairpin-helix motif - - - 0.0000000000000000000000000000000000000000000000000001674 205.0
HFD2_k127_2735858_4 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.0000000000000000000000000000000000000000000000000009052 186.0
HFD2_k127_2773490_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K18307 - - 0.0 1432.0
HFD2_k127_2773490_1 ATP synthesis coupled electron transport K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 449.0
HFD2_k127_2773490_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 371.0
HFD2_k127_2773490_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000004964 102.0
HFD2_k127_2773490_4 PFAM Outer membrane efflux protein - - - 0.00003948 52.0
HFD2_k127_2795913_0 ferredoxin-NADP+ reductase activity K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 452.0
HFD2_k127_2795913_1 Domain of unknown function (DUF1730) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005512 323.0
HFD2_k127_2795913_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 317.0
HFD2_k127_2795913_3 4fe-4S ferredoxin, iron-sulfur binding domain protein K03522,K05337 - - 0.0000000000000000000000000000000000000008403 151.0
HFD2_k127_2795913_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000239 140.0
HFD2_k127_2795913_5 Domain of unknown function (DUF309) K09763 - - 0.000000000000000000002511 96.0
HFD2_k127_2856545_0 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008282 246.0
HFD2_k127_2856545_1 5'-nucleotidase K01081,K01119,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000001228 239.0
HFD2_k127_2856545_2 regulation of translation K03530,K05788 - - 0.0000000000000000000000000000003107 128.0
HFD2_k127_2856545_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000001358 113.0
HFD2_k127_2856545_4 - - - - 0.00000000000007295 79.0
HFD2_k127_2856545_5 - - - - 0.0003703 43.0
HFD2_k127_2887415_0 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 8.003e-201 636.0
HFD2_k127_2887415_1 Belongs to the 5'-nucleotidase family - - - 0.00000000000000002129 94.0
HFD2_k127_2887415_2 SusE outer membrane protein K01216,K12287 - 3.2.1.73 0.0000000000000000577 93.0
HFD2_k127_2887415_3 - - - - 0.00000000000002734 83.0
HFD2_k127_2887415_4 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000008596 78.0
HFD2_k127_2962169_0 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 458.0
HFD2_k127_2962169_1 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 430.0
HFD2_k127_2962169_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000001327 214.0
HFD2_k127_2962169_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000241 126.0
HFD2_k127_2962169_5 deoxyhypusine monooxygenase activity - - - 0.0000000001487 70.0
HFD2_k127_2965126_0 Angiotensin-converting enzyme K01283 - 3.4.15.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 604.0
HFD2_k127_2965126_1 5-(carboxyamino)imidazole ribonucleotide synthase activity K01589 GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 395.0
HFD2_k127_2965126_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 353.0
HFD2_k127_2965126_3 isoprenoid biosynthetic process K13787,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000005167 246.0
HFD2_k127_2965126_4 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000007255 222.0
HFD2_k127_2965126_5 phosphoenolpyruvate-dependent sugar phosphotransferase system K11189 - - 0.00000000000000000000000001078 116.0
HFD2_k127_2965126_7 Angiotensin-converting enzyme - - - 0.0000000000000000000001105 113.0
HFD2_k127_2965126_8 heme binding K21471 - - 0.00000000000000003091 97.0
HFD2_k127_30110_0 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 466.0
HFD2_k127_30110_1 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 376.0
HFD2_k127_30110_11 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.00000008049 58.0
HFD2_k127_30110_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 317.0
HFD2_k127_30110_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000001339 247.0
HFD2_k127_30110_4 Peptidase family M23 - - - 0.0000000000000000000000000000000000000002455 161.0
HFD2_k127_30110_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.0000000000000000000000000000000000000002787 154.0
HFD2_k127_30110_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000007377 145.0
HFD2_k127_30110_7 COG494 NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair General function prediction only K01515 - 3.6.1.13 0.000000000000000000000000002029 120.0
HFD2_k127_30110_8 Polymer-forming cytoskeletal - - - 0.0000000000000000000003083 100.0
HFD2_k127_30110_9 ATP hydrolysis coupled proton transport K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000002393 95.0
HFD2_k127_3053092_0 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 2.2e-240 758.0
HFD2_k127_3053092_1 TIGRFAM Carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 371.0
HFD2_k127_3053092_2 cell redox homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000001105 248.0
HFD2_k127_3053092_3 rRNA processing K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000005746 209.0
HFD2_k127_3053092_4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000000000000006236 191.0
HFD2_k127_3053092_5 CarboxypepD_reg-like domain - - - 0.0009151 50.0
HFD2_k127_3091658_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.000000000000000000000000000000000000000006165 155.0
HFD2_k127_3091658_1 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000004175 96.0
HFD2_k127_3091658_2 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000242 87.0
HFD2_k127_3091658_3 Belongs to the peptidase S8 family - - - 0.0000000000008802 82.0
HFD2_k127_3091658_4 - - - - 0.00000001397 59.0
HFD2_k127_3091658_5 PFAM Uncharacterised BCR, COG1649 - - - 0.0002883 54.0
HFD2_k127_3158766_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006188 558.0
HFD2_k127_3158766_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 436.0
HFD2_k127_3158766_2 Histidine kinase K07709,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 396.0
HFD2_k127_3158766_3 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 342.0
HFD2_k127_3158766_4 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03072,K03074,K12257 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004861 268.0
HFD2_k127_3158766_5 peptide catabolic process - - - 0.00000000000000000000000000000007856 144.0
HFD2_k127_3158766_6 STAS domain K04749 - - 0.0000000000000000000000000004471 118.0
HFD2_k127_3158766_8 Predicted membrane protein (DUF2085) - - - 0.00007225 51.0
HFD2_k127_3176120_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 521.0
HFD2_k127_3176120_1 C-terminal domain of 1-Cys peroxiredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 383.0
HFD2_k127_3176120_10 tetratricopeptide repeat - - - 0.00002421 57.0
HFD2_k127_3176120_11 AAA ATPase domain - - - 0.000341 52.0
HFD2_k127_3176120_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000009265 246.0
HFD2_k127_3176120_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000001136 197.0
HFD2_k127_3176120_4 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000002937 185.0
HFD2_k127_3176120_5 membrane-bound metal-dependent K07038 - - 0.000000000000000000000000001528 130.0
HFD2_k127_3176120_6 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000005956 115.0
HFD2_k127_3176120_7 PAS fold - - - 0.00000000000000000000003065 111.0
HFD2_k127_3176120_9 Tetratricopeptide repeat - - - 0.0000000004463 73.0
HFD2_k127_3195837_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 632.0
HFD2_k127_3195837_1 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 538.0
HFD2_k127_3195837_10 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000008171 211.0
HFD2_k127_3195837_11 - - - - 0.0000000000013 70.0
HFD2_k127_3195837_2 PFAM ABC transporter related K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 452.0
HFD2_k127_3195837_3 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH K22136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 438.0
HFD2_k127_3195837_4 Cytochrome b(N-terminal)/b6/petB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 390.0
HFD2_k127_3195837_5 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 317.0
HFD2_k127_3195837_6 Cytochrome b(C-terminal)/b6/petD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 309.0
HFD2_k127_3195837_7 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 306.0
HFD2_k127_3195837_8 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000000000000000000009074 234.0
HFD2_k127_3195837_9 Phosphorylase superfamily K00772,K03783 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000001673 231.0
HFD2_k127_3313183_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 579.0
HFD2_k127_3313183_1 bis(5'-adenosyl)-triphosphatase activity K19710 GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.7.53 0.000000000000000000000000000000000000000000000000000001571 195.0
HFD2_k127_3313183_2 PFAM sigma-70 region 2 domain protein K03088 - - 0.0000000000000000000000000000000000000000000000000002081 190.0
HFD2_k127_3313183_4 Putative zinc-finger - - - 0.0004426 50.0
HFD2_k127_3352988_0 Glycosyl hydrolase family 92 - - - 3.861e-284 896.0
HFD2_k127_3352988_1 Glycosyl hydrolase family 20, domain 2 K12373 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000003952 226.0
HFD2_k127_3365465_0 peptidase activity, acting on L-amino acid peptides - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 544.0
HFD2_k127_3365465_1 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000007283 113.0
HFD2_k127_341858_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 535.0
HFD2_k127_341858_1 arabinose-5-phosphate isomerase activity K01627,K03281,K06041 - 2.5.1.55,5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006011 397.0
HFD2_k127_341858_10 ApaG domain K06195 - - 0.00000000000000000000000000000000000000001514 156.0
HFD2_k127_341858_11 lipopolysaccharide transmembrane transporter activity K09774,K11719 - - 0.000000000000000000000000000000000000001099 154.0
HFD2_k127_341858_12 RDD family - - - 0.000000000000000000000000000000000000299 146.0
HFD2_k127_341858_13 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.00000000000000000000000000000000001841 141.0
HFD2_k127_341858_14 cytokinin biosynthetic process K06966 - 3.2.2.10 0.000000000000000000000000000000001835 136.0
HFD2_k127_341858_16 - - - - 0.0000000000000000003481 100.0
HFD2_k127_341858_2 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 374.0
HFD2_k127_341858_3 ATP-dependent DNA helicase activity K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 369.0
HFD2_k127_341858_4 PFAM ABC transporter related K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 355.0
HFD2_k127_341858_5 Belongs to the KdsA family K01627 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0022607,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007717 322.0
HFD2_k127_341858_6 aminopeptidase activity K07004 - - 0.00000000000000000000000000000000000000000000000000000000000000006831 251.0
HFD2_k127_341858_7 OstA-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000004839 229.0
HFD2_k127_341858_8 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000001502 221.0
HFD2_k127_341858_9 cobalamin-transporting ATPase activity K02014 - - 0.000000000000000000000000000000000000000000000597 188.0
HFD2_k127_3458076_0 homoserine dehydrogenase K12524 - 1.1.1.3,2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000002064 266.0
HFD2_k127_3458076_1 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000003114 254.0
HFD2_k127_3479768_0 - - - - 0.0000000000000000000000000000000000000002756 160.0
HFD2_k127_3479768_1 PFAM Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000009227 93.0
HFD2_k127_3479768_2 amine dehydrogenase activity - - - 0.000000002228 68.0
HFD2_k127_3538095_0 phosphate starvation-inducible protein PhoH K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 431.0
HFD2_k127_3538095_1 TIGRFAM MazG family protein K02428,K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 312.0
HFD2_k127_3538095_2 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001214 255.0
HFD2_k127_3538095_3 positive regulation of growth rate - - - 0.000000000000000000000000000244 124.0
HFD2_k127_3538095_4 Amidohydrolase family - - - 0.0000000000000000000000005077 110.0
HFD2_k127_3538095_6 PFAM Receptor family ligand binding region K01999 - - 0.0001045 55.0
HFD2_k127_3554324_0 serine-type endopeptidase activity K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 446.0
HFD2_k127_3554324_1 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000317 115.0
HFD2_k127_3575958_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 379.0
HFD2_k127_3575958_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000002032 199.0
HFD2_k127_3575958_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K13531 - 2.1.1.63 0.00000000000000000000000000000000000000005087 161.0
HFD2_k127_3600549_0 glycogen (starch) synthase activity K00703,K00754 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 363.0
HFD2_k127_3600549_1 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 357.0
HFD2_k127_3600549_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000199 146.0
HFD2_k127_3600549_3 SH2 domain binding K08399,K15176 GO:0000003,GO:0000122,GO:0000428,GO:0000785,GO:0000993,GO:0001098,GO:0001099,GO:0001701,GO:0001704,GO:0001706,GO:0001711,GO:0001824,GO:0001825,GO:0001826,GO:0001829,GO:0001832,GO:0002237,GO:0002682,GO:0002683,GO:0003006,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0006139,GO:0006325,GO:0006351,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006464,GO:0006479,GO:0006513,GO:0006725,GO:0006807,GO:0006996,GO:0007154,GO:0007165,GO:0007166,GO:0007259,GO:0007275,GO:0007276,GO:0007281,GO:0007369,GO:0007399,GO:0007406,GO:0007492,GO:0008023,GO:0008150,GO:0008152,GO:0008213,GO:0008285,GO:0009058,GO:0009059,GO:0009605,GO:0009607,GO:0009617,GO:0009653,GO:0009790,GO:0009792,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010390,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010638,GO:0010721,GO:0016043,GO:0016070,GO:0016567,GO:0016569,GO:0016570,GO:0016571,GO:0016574,GO:0016591,GO:0016593,GO:0018022,GO:0018023,GO:0018130,GO:0018193,GO:0018205,GO:0019219,GO:0019221,GO:0019222,GO:0019438,GO:0019538,GO:0019827,GO:0019899,GO:0019904,GO:0019953,GO:0022008,GO:0022412,GO:0022414,GO:0023052,GO:0030154,GO:0030880,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031396,GO:0031398,GO:0031399,GO:0031401,GO:0031440,GO:0031441,GO:0031974,GO:0031981,GO:0032259,GO:0032268,GO:0032270,GO:0032446,GO:0032496,GO:0032501,GO:0032502,GO:0032504,GO:0032774,GO:0032784,GO:0032786,GO:0032968,GO:0032991,GO:0033043,GO:0033044,GO:0033182,GO:0033184,GO:0033523,GO:0033993,GO:0034097,GO:0034243,GO:0034641,GO:0034645,GO:0034654,GO:0034968,GO:0035327,GO:0035556,GO:0035987,GO:0036211,GO:0040007,GO:0042127,GO:0042169,GO:0042221,GO:0043009,GO:0043170,GO:0043175,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0044703,GO:0044877,GO:0045165,GO:0045595,GO:0045596,GO:0045637,GO:0045638,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0046483,GO:0048468,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048589,GO:0048598,GO:0048609,GO:0048646,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050684,GO:0050686,GO:0050767,GO:0050768,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051093,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051568,GO:0051569,GO:0051571,GO:0051704,GO:0051707,GO:0051716,GO:0051960,GO:0051961,GO:0055029,GO:0060255,GO:0060284,GO:0060795,GO:0061695,GO:0065007,GO:0070013,GO:0070063,GO:0070102,GO:0070647,GO:0070741,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071345,GO:0071354,GO:0071396,GO:0071704,GO:0071840,GO:0072091,GO:0080090,GO:0080182,GO:0090304,GO:0097659,GO:0097696,GO:0098727,GO:1900363,GO:1900364,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901700,GO:1901701,GO:1902275,GO:1902494,GO:1902679,GO:1902680,GO:1902692,GO:1903311,GO:1903312,GO:1903320,GO:1903322,GO:1903506,GO:1903507,GO:1903508,GO:1903706,GO:1903707,GO:1905269,GO:1990234,GO:2000026,GO:2000112,GO:2000113,GO:2000177,GO:2000178,GO:2000647,GO:2000653,GO:2001141,GO:2001160,GO:2001162,GO:2001166,GO:2001168,GO:2001252 - 0.0004157 50.0
HFD2_k127_3636240_0 deaminase activity K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 531.0
HFD2_k127_3636240_1 PFAM Phenylalanine and histidine ammonia-lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 492.0
HFD2_k127_3636240_10 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000006005 148.0
HFD2_k127_3636240_11 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000003428 94.0
HFD2_k127_3636240_12 peptidylprolyl isomerase K03769,K07533 - 5.2.1.8 0.0000000006378 70.0
HFD2_k127_3636240_2 Associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000582 463.0
HFD2_k127_3636240_3 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 477.0
HFD2_k127_3636240_4 peptidyl-prolyl cis-trans isomerase activity K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 379.0
HFD2_k127_3636240_5 lipase activity K15349 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007206 351.0
HFD2_k127_3636240_6 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 359.0
HFD2_k127_3636240_7 peptidyl-prolyl cis-trans isomerase activity K03769,K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 355.0
HFD2_k127_3636240_8 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 291.0
HFD2_k127_3636240_9 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000001212 229.0
HFD2_k127_3662800_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 379.0
HFD2_k127_3662800_1 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 348.0
HFD2_k127_3662800_2 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 285.0
HFD2_k127_3662800_3 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006493 287.0
HFD2_k127_3662800_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000001803 188.0
HFD2_k127_3662800_5 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000002173 155.0
HFD2_k127_3662800_6 - - - - 0.0000000000000000000000000000000008945 137.0
HFD2_k127_3662800_7 methylamine metabolic process - - - 0.00000000000000000000000000202 118.0
HFD2_k127_3662800_8 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000001301 82.0
HFD2_k127_3662800_9 Rhodanese Homology Domain - - - 0.000000000005022 76.0
HFD2_k127_37220_0 Molybdopterin oxidoreductase Fe4S4 domain K00370 - 1.7.5.1 6.638e-294 913.0
HFD2_k127_37220_1 4Fe-4S dicluster domain K00184 - - 7.331e-282 896.0
HFD2_k127_37220_10 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 336.0
HFD2_k127_37220_11 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000002441 231.0
HFD2_k127_37220_12 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000001446 231.0
HFD2_k127_37220_13 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000001982 228.0
HFD2_k127_37220_14 nitrate reductase activity K00370,K00374,K02575 GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000002378 213.0
HFD2_k127_37220_15 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000000000000000000000000000001407 199.0
HFD2_k127_37220_16 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000006203 187.0
HFD2_k127_37220_17 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000003792 166.0
HFD2_k127_37220_18 methyltransferase - - - 0.0000000000000000000000000000000000000009081 152.0
HFD2_k127_37220_19 peroxiredoxin activity K01607 - 4.1.1.44 0.000000000000000000000000000000000000006386 148.0
HFD2_k127_37220_2 nitrate reductase beta subunit K00371 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 2.465e-231 725.0
HFD2_k127_37220_20 cytochrome c - - - 0.000000000000000000000000000000000000007102 153.0
HFD2_k127_37220_21 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000004603 136.0
HFD2_k127_37220_22 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.00000000000000000000000000000002764 139.0
HFD2_k127_37220_23 Protein of unknown function (DUF2721) - - - 0.000000000000000000000007425 112.0
HFD2_k127_37220_24 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.000000000000000000000008777 108.0
HFD2_k127_37220_25 Antibiotic biosynthesis monooxygenase - - - 0.0004352 49.0
HFD2_k127_37220_3 Polysulphide reductase, NrfD K00185 - - 1.078e-223 701.0
HFD2_k127_37220_4 PFAM Major Facilitator Superfamily K02575 - - 1.873e-212 674.0
HFD2_k127_37220_5 Transporter K02575 - - 4.387e-194 615.0
HFD2_k127_37220_6 Belongs to the cysteine synthase cystathionine beta- synthase family K01697,K01738,K12339 - 2.5.1.47,4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 501.0
HFD2_k127_37220_7 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 466.0
HFD2_k127_37220_8 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 393.0
HFD2_k127_37220_9 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 334.0
HFD2_k127_3735276_0 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 567.0
HFD2_k127_3735276_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 548.0
HFD2_k127_3735276_2 - - - - 0.0000000000000000000000000004825 115.0
HFD2_k127_3735276_3 Domain of unknown function (DUF309) K09763 - - 0.000000000000000000004102 96.0
HFD2_k127_3761070_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 5.643e-296 934.0
HFD2_k127_3761070_1 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 575.0
HFD2_k127_3761070_2 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000698 401.0
HFD2_k127_3761070_3 Sulfatase-modifying factor enzyme 1 K01176,K01206,K01218,K01219,K01224 - 3.2.1.1,3.2.1.51,3.2.1.78,3.2.1.81,3.2.1.89 0.00000000000000000000000000000000000000004416 176.0
HFD2_k127_3761070_4 D-glycero-D-manno-heptose 7-phosphate metabolic process K03271 - 5.3.1.28 0.00000000000000000000000000000000000001084 149.0
HFD2_k127_3761070_5 PFAM ATP-dependent Clp protease adaptor protein ClpS - - - 0.0000000000000000000000007529 108.0
HFD2_k127_3764657_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 568.0
HFD2_k127_3764657_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002719 266.0
HFD2_k127_3764657_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009979 268.0
HFD2_k127_3764657_3 glutamine synthetase K01915 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000007298 250.0
HFD2_k127_3764657_4 helix_turn_helix ASNC type K03719 - - 0.0000000000000000000000000000000000000000000000000001869 189.0
HFD2_k127_3764657_5 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000608 188.0
HFD2_k127_3764657_6 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000000000000000005256 178.0
HFD2_k127_380529_0 COGs COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system - - - 1.257e-223 740.0
HFD2_k127_380529_1 8-amino-7-oxononanoate synthase activity K00639,K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 1.155e-200 631.0
HFD2_k127_380529_10 protein transport K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000004651 245.0
HFD2_k127_380529_11 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000004969 233.0
HFD2_k127_380529_12 Polynucleotide kinase 3 phosphatase - - - 0.00000000000000000000000000000000000000000000001446 184.0
HFD2_k127_380529_13 sugar-phosphate isomerases, RpiB LacA LacB family K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000704 160.0
HFD2_k127_380529_14 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000001007 153.0
HFD2_k127_380529_15 Psort location OuterMembrane, score - - - 0.000000000000000000000000000000008491 142.0
HFD2_k127_380529_17 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K01406 - 3.4.24.40 0.0000003581 63.0
HFD2_k127_380529_18 Hep Hag repeat protein K08961 - 4.2.2.20,4.2.2.21 0.000004948 57.0
HFD2_k127_380529_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 4.546e-199 632.0
HFD2_k127_380529_3 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 512.0
HFD2_k127_380529_4 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006179 452.0
HFD2_k127_380529_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008105 428.0
HFD2_k127_380529_6 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 383.0
HFD2_k127_380529_7 isoprenoid biosynthetic process K00805,K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.30,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 377.0
HFD2_k127_380529_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 346.0
HFD2_k127_380529_9 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 302.0
HFD2_k127_380671_0 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 362.0
HFD2_k127_380671_1 CTP synthase activity K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 0.000000000000000000000000000000000000000000000000000000000000000001062 244.0
HFD2_k127_380671_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000003201 250.0
HFD2_k127_380671_3 phosphatidate phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002565 240.0
HFD2_k127_380671_4 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000002441 167.0
HFD2_k127_380671_5 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000004199 152.0
HFD2_k127_380671_6 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000005088 112.0
HFD2_k127_385931_0 single-stranded DNA 5'-3' exodeoxyribonuclease activity K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 614.0
HFD2_k127_385931_1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 363.0
HFD2_k127_385931_11 nuclease activity K07064 - - 0.0002502 51.0
HFD2_k127_385931_2 NIF3 (NGG1p interacting factor 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 321.0
HFD2_k127_385931_3 GGDEF domain K02478 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000006258 249.0
HFD2_k127_385931_4 - K07164,K22391 - 3.5.4.16 0.000000000000000000000000000000000000000000000008966 182.0
HFD2_k127_385931_5 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000001864 172.0
HFD2_k127_385931_6 Ethanolamine utilization protein EutN K04028 - - 0.000000000000000000000000000000007807 129.0
HFD2_k127_385931_7 Reverse transcriptase-like K03469,K06864 - 3.1.26.4 0.00000000000000000000000000009984 123.0
HFD2_k127_385931_8 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.0000000000000000000000000005937 114.0
HFD2_k127_385931_9 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000003595 98.0
HFD2_k127_3864373_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 452.0
HFD2_k127_3864373_1 PFAM glycosyl hydrolase BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008409 445.0
HFD2_k127_3864373_10 Antibiotic biosynthesis monooxygenase - - - 0.0002175 52.0
HFD2_k127_3864373_2 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 338.0
HFD2_k127_3864373_3 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002118 265.0
HFD2_k127_3864373_5 thioesterase K07107,K12500 - - 0.0000000000000000000000000000000000000000000004326 169.0
HFD2_k127_3864373_7 Glycosyl transferases group 1 K19424 - - 0.000000000000000000000000000000000005551 153.0
HFD2_k127_3864373_9 PFAM Cys Met metabolism pyridoxal-phosphate- dependent protein K01739,K01758,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11 0.00000000002928 68.0
HFD2_k127_3890425_0 phosphopyruvate hydratase activity K01689 GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 608.0
HFD2_k127_3890425_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 - 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 577.0
HFD2_k127_3890425_2 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 447.0
HFD2_k127_3890425_3 involved in cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001586 258.0
HFD2_k127_3890425_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000684 224.0
HFD2_k127_3890425_5 Glycosyl transferase, family 9 K02841,K02843,K02847,K02849,K21003 - - 0.00000000000000000000000000000000000000000000000000000004426 209.0
HFD2_k127_3890425_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000002938 213.0
HFD2_k127_3890425_7 Protein conserved in bacteria K09922 - - 0.000000000000000000000000000000000000000000002293 167.0
HFD2_k127_3890425_8 Thioredoxin-like - - - 0.0000000000000000000000001616 113.0
HFD2_k127_389468_0 Response regulator, receiver K01007 - 2.7.9.2 0.0 1188.0
HFD2_k127_389468_1 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 2e-322 1004.0
HFD2_k127_389468_2 acetyl-CoA hydrolase activity K01067 - 3.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 580.0
HFD2_k127_389468_3 alanine dehydrogenase activity K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 401.0
HFD2_k127_389468_4 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.00000000000000000000000003573 112.0
HFD2_k127_389468_5 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.000000000002069 66.0
HFD2_k127_389468_6 Thioredoxin domain - - - 0.00000001082 59.0
HFD2_k127_3942787_0 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 612.0
HFD2_k127_3942787_1 Cytochrome C and Quinol oxidase polypeptide I K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005854 528.0
HFD2_k127_3942787_10 Cytochrome oxidase assembly protein K02259 - - 0.000000000000000000000000000000000000000000000000000000003736 216.0
HFD2_k127_3942787_11 2 iron, 2 sulfur cluster binding K02823 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016646,GO:0042602,GO:0052875,GO:0055114 - 0.000000000000000000000000000000000000000000000000000003936 199.0
HFD2_k127_3942787_12 protein trimerization - - - 0.000000000000000000000000000000000000000000001023 189.0
HFD2_k127_3942787_13 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000006683 156.0
HFD2_k127_3942787_14 Protein of unknown function (DUF420) K08976 - - 0.0000000000000000000000000000000000001372 148.0
HFD2_k127_3942787_15 SCO1/SenC K07152 - - 0.00000000000000000000000000000000003371 146.0
HFD2_k127_3942787_16 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.000005617 53.0
HFD2_k127_3942787_2 dihydroorotate dehydrogenase activity K00226,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 345.0
HFD2_k127_3942787_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008187 328.0
HFD2_k127_3942787_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000002849 250.0
HFD2_k127_3942787_5 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000004082 239.0
HFD2_k127_3942787_6 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000004582 244.0
HFD2_k127_3942787_7 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000008411 226.0
HFD2_k127_3942787_8 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000001336 235.0
HFD2_k127_3942787_9 Lipocalin / cytosolic fatty-acid binding protein family K03098 - - 0.00000000000000000000000000000000000000000000000000000000000542 215.0
HFD2_k127_3969133_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 295.0
HFD2_k127_3969133_1 long-chain fatty acid transporting porin activity K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000002564 248.0
HFD2_k127_3969133_2 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000004069 220.0
HFD2_k127_3969133_3 COG2143 Thioredoxin-related protein - - - 0.0000000000000000000000000001176 124.0
HFD2_k127_398122_0 AcrB/AcrD/AcrF family - - - 2.684e-243 780.0
HFD2_k127_398122_1 PFAM GlcNAc-PI de-N-acetylase - - - 2.178e-232 746.0
HFD2_k127_398122_10 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000001266 234.0
HFD2_k127_398122_11 Nucleoside recognition K06373,K06374 - - 0.0000000000000000000000000000000000000000000000000000000000000004228 224.0
HFD2_k127_398122_12 Spore maturation protein K06373 - - 0.00000000000000000000000000000000000000000000000000000000000005042 228.0
HFD2_k127_398122_13 aminopeptidase activity K07004 - - 0.00000000000000000000000000000000000000000000000000000009595 219.0
HFD2_k127_398122_14 HlyD family secretion protein K03585 - - 0.00000000000000000000000000000000000000000000000000001567 204.0
HFD2_k127_398122_15 DinB family - - - 0.000000000000000000000000000000000000000000005904 169.0
HFD2_k127_398122_16 COG0791 Cell wall-associated hydrolases (invasion-associated proteins) K13694,K13695 - 3.4.17.13 0.0000000000000000000002178 105.0
HFD2_k127_398122_17 Antibiotic biosynthesis monooxygenase - - - 0.00000000000001013 79.0
HFD2_k127_398122_18 SnoaL-like domain - - - 0.00000000000005382 78.0
HFD2_k127_398122_2 oligopeptide transporter, OPT family - - - 1.403e-220 702.0
HFD2_k127_398122_3 TIGRFAM aminoacyl-histidine dipeptidase K01270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000784 575.0
HFD2_k127_398122_4 PFAM OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 561.0
HFD2_k127_398122_5 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 434.0
HFD2_k127_398122_6 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 371.0
HFD2_k127_398122_7 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 313.0
HFD2_k127_398122_8 proline dehydrogenase activity K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 312.0
HFD2_k127_398122_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 306.0
HFD2_k127_4006134_0 Sodium:neurotransmitter symporter family - - - 4.257e-210 665.0
HFD2_k127_4006134_1 transferase activity, transferring glycosyl groups K00754 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 519.0
HFD2_k127_4006134_2 MgtC family K07507 - - 0.00000000000000000000000000000000000000000653 165.0
HFD2_k127_4006134_3 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102 - - 0.0000000000002427 71.0
HFD2_k127_4060328_0 GTPase activity K03596 - - 1.768e-290 902.0
HFD2_k127_4060328_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 3.114e-229 740.0
HFD2_k127_4060328_10 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000528 205.0
HFD2_k127_4060328_11 PFAM Glycosyl transferase, group 1 K12996 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000000000000000000005826 181.0
HFD2_k127_4060328_12 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000004571 184.0
HFD2_k127_4060328_13 Sulfatase-modifying factor enzyme 1 K01176,K01206,K01218,K01219,K01224 - 3.2.1.1,3.2.1.51,3.2.1.78,3.2.1.81,3.2.1.89 0.00000000000000000000000000000000000002021 166.0
HFD2_k127_4060328_14 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000008297 140.0
HFD2_k127_4060328_15 - - - - 0.0000000000000000000000000000007056 130.0
HFD2_k127_4060328_16 cell adhesion involved in biofilm formation K20276 - - 0.0000000000000000000000000002357 135.0
HFD2_k127_4060328_17 Polysaccharide biosynthesis protein - - - 0.00000000000001044 83.0
HFD2_k127_4060328_18 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.00000000005525 72.0
HFD2_k127_4060328_19 - - - - 0.0000000156 66.0
HFD2_k127_4060328_2 Oligopeptidase F K08602 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 2.623e-204 660.0
HFD2_k127_4060328_3 serine-type endopeptidase activity K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000828 539.0
HFD2_k127_4060328_4 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 412.0
HFD2_k127_4060328_5 coproporphyrinogen oxidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 376.0
HFD2_k127_4060328_6 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 341.0
HFD2_k127_4060328_7 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 323.0
HFD2_k127_4060328_8 signal peptide processing K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000002466 269.0
HFD2_k127_4060328_9 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000009963 221.0
HFD2_k127_4094328_0 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004889 231.0
HFD2_k127_4094328_1 - - - - 0.000000000000000000000000000000000000000003038 170.0
HFD2_k127_4134666_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 1.853e-195 617.0
HFD2_k127_4134666_1 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 391.0
HFD2_k127_4134666_2 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000085 166.0
HFD2_k127_4134666_3 glutamate dehydrogenase [NAD(P)+] activity K00262 - 1.4.1.4 0.00000000000000000000001317 104.0
HFD2_k127_4134666_4 Rubrerythrin - - - 0.000000000000000004936 96.0
HFD2_k127_4135704_0 glucuronate isomerase activity K01812 GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019585,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0042839,GO:0042840,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0071704,GO:0072329,GO:1901575 5.3.1.12 5.77e-213 671.0
HFD2_k127_4135704_1 Major facilitator superfamily K08191 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 568.0
HFD2_k127_4135704_2 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 557.0
HFD2_k127_4135704_3 tagaturonate epimerase K21619 - 5.1.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006646 503.0
HFD2_k127_4135704_4 PFAM Short-chain dehydrogenase reductase SDR K00046,K00065 - 1.1.1.127,1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 306.0
HFD2_k127_4135704_5 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 304.0
HFD2_k127_4135704_6 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 299.0
HFD2_k127_4135704_7 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate K01815 - 5.3.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 302.0
HFD2_k127_4135704_8 Pectinesterase K01051 - 3.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000001078 284.0
HFD2_k127_4135704_9 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000001463 128.0
HFD2_k127_4180301_0 translation elongation factor activity K02358,K15771 GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0010467,GO:0016020,GO:0019538,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0034641,GO:0034645,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071704,GO:0071944,GO:0090087,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - 3.423e-214 684.0
HFD2_k127_4180301_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 585.0
HFD2_k127_4180301_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 518.0
HFD2_k127_4180301_3 rRNA binding K02906 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003443 263.0
HFD2_k127_4180301_4 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000003615 218.0
HFD2_k127_4180301_5 rRNA binding K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000000001549 216.0
HFD2_k127_4180301_6 DNA-directed 5'-3' RNA polymerase activity K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000101 182.0
HFD2_k127_4180301_7 cytoplasmic translation K02946 GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000006888 173.0
HFD2_k127_4209996_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 601.0
HFD2_k127_4209996_1 deoxyribose-phosphate aldolase activity K00852,K01619,K01840,K01844 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.1.15,4.1.2.4,5.4.2.8,5.4.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 314.0
HFD2_k127_4209996_2 chaperone-mediated protein folding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 308.0
HFD2_k127_4209996_3 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001595 273.0
HFD2_k127_4209996_4 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002428 247.0
HFD2_k127_4209996_5 ZIP Zinc transporter K07238,K11021,K16267 - - 0.000000000000000000000000000000000000000000000000001068 192.0
HFD2_k127_4209996_6 Enoyl-CoA hydratase K01715 - 4.2.1.17 0.000000000000000000000000000000007297 130.0
HFD2_k127_4212132_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 557.0
HFD2_k127_4212132_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 449.0
HFD2_k127_4212132_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000415 212.0
HFD2_k127_4212132_3 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000002299 145.0
HFD2_k127_4212132_4 rRNA methyltransferase - - - 0.0000000000000000000000000000000000002672 147.0
HFD2_k127_4221063_0 PFAM Glycoside hydrolase 15-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008294 404.0
HFD2_k127_4228599_0 E1-E2 ATPase K12949,K12956,K17686 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0009405,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0042221,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046688,GO:0050896,GO:0051704,GO:0071944 3.6.3.54 3.246e-219 703.0
HFD2_k127_4228599_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 539.0
HFD2_k127_4228599_10 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000004386 99.0
HFD2_k127_4228599_11 calcium- and calmodulin-responsive adenylate cyclase activity K01179 - 3.2.1.4 0.00000000000000001614 99.0
HFD2_k127_4228599_12 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K07081,K11782,K11784 - 1.21.98.1,4.2.1.151 0.0000000000000001374 91.0
HFD2_k127_4228599_13 Belongs to the UPF0109 family K06960 - - 0.0000000000000004089 80.0
HFD2_k127_4228599_14 Heavy-metal-associated domain K07213 - - 0.000000000009593 68.0
HFD2_k127_4228599_2 Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 472.0
HFD2_k127_4228599_3 TIGRFAM threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 381.0
HFD2_k127_4228599_4 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 291.0
HFD2_k127_4228599_5 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 286.0
HFD2_k127_4228599_6 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002292 241.0
HFD2_k127_4228599_7 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000001151 213.0
HFD2_k127_4228599_8 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000002471 152.0
HFD2_k127_4228599_9 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000001979 135.0
HFD2_k127_4277819_0 NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 319.0
HFD2_k127_4277819_1 peptidase activity, acting on L-amino acid peptides K01337,K13735,K20276 - 3.4.21.50 0.0000000000000000000000000000006175 143.0
HFD2_k127_4277819_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008194,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.00009892 51.0
HFD2_k127_4277819_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0005206 47.0
HFD2_k127_42786_0 acyl-CoA dehydrogenase activity K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 527.0
HFD2_k127_42786_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 420.0
HFD2_k127_42786_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 389.0
HFD2_k127_4372508_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 7.989e-241 755.0
HFD2_k127_4372508_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004442 432.0
HFD2_k127_4372508_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 325.0
HFD2_k127_4372508_3 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005924 278.0
HFD2_k127_4372508_4 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000001038 164.0
HFD2_k127_4373050_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 1.247e-274 855.0
HFD2_k127_4373050_1 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003895 278.0
HFD2_k127_4380575_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 488.0
HFD2_k127_4380575_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 436.0
HFD2_k127_4380575_10 PFAM Uncharacterised BCR, COG1649 K01186,K01197,K05988,K11931,K18197 - 3.2.1.11,3.2.1.18,3.2.1.35,4.2.2.23 0.00000000000000000004873 102.0
HFD2_k127_4380575_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 401.0
HFD2_k127_4380575_3 metalloendopeptidase activity K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009388 378.0
HFD2_k127_4380575_4 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 370.0
HFD2_k127_4380575_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005511 394.0
HFD2_k127_4380575_6 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000001422 276.0
HFD2_k127_4380575_7 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000104 221.0
HFD2_k127_4380575_8 Protein of unknown function (DUF1460) - - - 0.0000000000000000000000000000000004785 136.0
HFD2_k127_4380575_9 FecR protein - - - 0.0000000000000000000000000005942 122.0
HFD2_k127_4404765_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 2.697e-228 723.0
HFD2_k127_4404765_1 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 551.0
HFD2_k127_4404765_10 - - - - 0.000000000000000002564 100.0
HFD2_k127_4404765_11 - - - - 0.00000000000001013 79.0
HFD2_k127_4404765_12 Pilus assembly protein PilX - - - 0.0000000001077 73.0
HFD2_k127_4404765_15 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000006763 66.0
HFD2_k127_4404765_2 protein transport across the cell outer membrane K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 506.0
HFD2_k127_4404765_3 porphobilinogen synthase activity K01698 GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 481.0
HFD2_k127_4404765_4 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009519 472.0
HFD2_k127_4404765_5 Type ii and iii secretion system protein K02666,K12282 - - 0.000000000000000000000000000000000000000000000000000000000000000000005656 250.0
HFD2_k127_4404765_6 cellulose binding K07279 - - 0.000000000000000000000000000000000000000000000000000004051 213.0
HFD2_k127_4404765_7 PFAM Fimbrial assembly family protein K02663 - - 0.00000000000000000000000000000000000000005981 170.0
HFD2_k127_4404765_8 - - - - 0.00000000000000000000008142 102.0
HFD2_k127_4404765_9 - - - - 0.000000000000000000004905 104.0
HFD2_k127_4415861_0 PFAM penicillin-binding protein transpeptidase K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 472.0
HFD2_k127_4415861_1 MraW methylase family K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000003654 256.0
HFD2_k127_4415861_2 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000000000000000000000000000004137 173.0
HFD2_k127_441931_0 quinolinate synthetase A activity K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 480.0
HFD2_k127_441931_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 475.0
HFD2_k127_441931_10 PFAM SMP-30 Gluconolaconase - - - 0.0005941 48.0
HFD2_k127_441931_2 Deoxynucleoside kinase K15518 - 2.7.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001368 280.0
HFD2_k127_441931_3 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000001038 250.0
HFD2_k127_441931_4 Major pilin protein fimA - - - 0.000000000000000000000000000000000000000000000000000000000000000002124 242.0
HFD2_k127_441931_5 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000002429 222.0
HFD2_k127_441931_6 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02841,K02843,K12982 - - 0.0000000000000000000000000000000000000000000000000000000002322 219.0
HFD2_k127_441931_7 PFAM Rhomboid family protein - - - 0.0000000000000000000000000000000005387 140.0
HFD2_k127_441931_8 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K09007,K13940,K17488 - 2.7.6.3,3.5.4.16,3.5.4.39,4.1.2.25 0.000000000000000000000000000000001491 135.0
HFD2_k127_441931_9 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000003823 126.0
HFD2_k127_4438130_0 phosphate acetyltransferase K00029,K00625,K13788 - 1.1.1.40,2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 396.0
HFD2_k127_4438130_1 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K07106,K09001 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 2.7.1.170,4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 351.0
HFD2_k127_4438130_2 deoxyribonuclease IV (phage-T4-induced) activity K01151 GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 328.0
HFD2_k127_4438130_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000272 261.0
HFD2_k127_4438130_4 Membrane - - - 0.00000000000000000000000000000000000000000001225 177.0
HFD2_k127_4439330_0 Peptidase m28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 526.0
HFD2_k127_4439330_1 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 455.0
HFD2_k127_4439330_2 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 433.0
HFD2_k127_4439330_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 351.0
HFD2_k127_4439330_4 - - - - 0.00000000000000000000000000000000000000000000000000001886 202.0
HFD2_k127_4439330_5 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000003615 106.0
HFD2_k127_4454076_0 TonB-dependent receptor K02014 - - 2.438e-211 681.0
HFD2_k127_4454076_1 C-terminal binding-module, SLH-like, of glucodextranase K01178,K01200 - 3.2.1.3,3.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 560.0
HFD2_k127_4454076_2 symporter activity K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 383.0
HFD2_k127_4454076_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 366.0
HFD2_k127_4454076_4 Transport permease protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 326.0
HFD2_k127_4454076_5 - K07283 - - 0.00000000000000000000000000000000000000004853 167.0
HFD2_k127_4454076_6 PFAM Thiamin pyrophosphokinase, catalytic region K00949 - 2.7.6.2 0.00000000000000000000000000005168 125.0
HFD2_k127_4454076_7 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000005113 113.0
HFD2_k127_4454076_8 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000002514 96.0
HFD2_k127_4460765_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 8.498e-275 871.0
HFD2_k127_4460765_1 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 607.0
HFD2_k127_4460765_10 metallopeptidase activity K07407 - 3.2.1.22 0.000408 43.0
HFD2_k127_4460765_2 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 387.0
HFD2_k127_4460765_3 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000153 209.0
HFD2_k127_4460765_4 DinB superfamily K07552 - - 0.000000000000000000000000000000000000002239 159.0
HFD2_k127_4460765_5 cell adhesion involved in biofilm formation K20276 - - 0.00000000000000000000000000000004799 146.0
HFD2_k127_4460765_6 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000002846 106.0
HFD2_k127_4460765_7 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000001181 99.0
HFD2_k127_4460765_8 Belongs to the peptidase S8 family - - - 0.000000000000541 82.0
HFD2_k127_4460765_9 cellulose binding - - - 0.000000001376 63.0
HFD2_k127_4470849_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 485.0
HFD2_k127_4470849_1 UDP-glucose 4-epimerase activity K01784,K17947 - 5.1.3.2,5.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 386.0
HFD2_k127_4470849_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 380.0
HFD2_k127_4470849_3 isobutyryl-CoA mutase activity K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 347.0
HFD2_k127_4470849_4 IMP dehydrogenase activity K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 325.0
HFD2_k127_4470849_5 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 311.0
HFD2_k127_452687_0 Alpha amylase, catalytic domain - - - 4.183e-320 1017.0
HFD2_k127_452687_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.306e-207 646.0
HFD2_k127_452687_10 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000005266 240.0
HFD2_k127_452687_11 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000225 240.0
HFD2_k127_452687_12 Trypsin-like serine protease - - - 0.00000000000000000000000000000000000000000000000000000000000001878 226.0
HFD2_k127_452687_13 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000002048 233.0
HFD2_k127_452687_14 TPM domain K06872 - - 0.00000000000000000000000000000000000000000005422 172.0
HFD2_k127_452687_15 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.00000000000000000000000000000000008295 137.0
HFD2_k127_452687_16 Putative zinc ribbon domain - - - 0.0000000000000000000000000000000001836 134.0
HFD2_k127_452687_17 membrane - - - 0.000000000000000000005832 100.0
HFD2_k127_452687_18 YCII-related domain - - - 0.000000028 61.0
HFD2_k127_452687_19 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000001329 64.0
HFD2_k127_452687_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 549.0
HFD2_k127_452687_3 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 526.0
HFD2_k127_452687_4 PFAM Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 515.0
HFD2_k127_452687_5 Aminotransferase class IV K03342 - 2.6.1.85,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009637 516.0
HFD2_k127_452687_6 Glycosyl hydrolase family 57 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 422.0
HFD2_k127_452687_7 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 403.0
HFD2_k127_452687_8 DEAD DEAH box helicase domain protein K05592,K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 321.0
HFD2_k127_452687_9 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K05827,K05844 - 6.3.2.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000002974 268.0
HFD2_k127_454501_0 metal-dependent hydrolase with the TIM-barrel fold - - - 1.627e-197 631.0
HFD2_k127_454501_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009621 485.0
HFD2_k127_454501_10 DinB superfamily - - - 0.000000000000000000000000000006271 128.0
HFD2_k127_454501_11 Belongs to the UPF0312 family - - - 0.00000000000000000000000003346 119.0
HFD2_k127_454501_12 EVE domain - - - 0.0000000000000000000000001189 113.0
HFD2_k127_454501_13 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000004006 112.0
HFD2_k127_454501_14 - - - - 0.0000000000000000000001899 104.0
HFD2_k127_454501_15 domain protein K06929 - - 0.0000000000000000006593 92.0
HFD2_k127_454501_16 Phosphoglycerate mutase family - - - 0.0000000000000008459 88.0
HFD2_k127_454501_17 Pilus assembly protein PilX K02673 - - 0.0000002193 63.0
HFD2_k127_454501_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000006524 248.0
HFD2_k127_454501_3 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000008141 187.0
HFD2_k127_454501_4 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000000000006881 184.0
HFD2_k127_454501_5 Cupin domain - - - 0.00000000000000000000000000000000000000000000009363 173.0
HFD2_k127_454501_6 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000000000000001658 164.0
HFD2_k127_454501_7 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.00000000000000000000000000000000000009046 146.0
HFD2_k127_454501_8 - - - - 0.000000000000000000000000000000113 128.0
HFD2_k127_454501_9 protocatechuate 3,4-dioxygenase activity K00449 - 1.13.11.3 0.000000000000000000000000000000129 132.0
HFD2_k127_4572348_0 nucleotide-excision repair K03702,K08999 GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 3.873e-293 912.0
HFD2_k127_4572348_1 AcrB/AcrD/AcrF family - - - 0.000000000000000000000000000000000000000000000000000000000003292 213.0
HFD2_k127_4572348_2 Phosphoribosyl transferase domain K00764 - 2.4.2.14 0.0000000000000000000000000000002629 132.0
HFD2_k127_4592148_0 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 361.0
HFD2_k127_4592148_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001452 287.0
HFD2_k127_4592148_2 polysaccharide deacetylase - - - 0.0000000000171 71.0
HFD2_k127_4658201_0 Belongs to the DegT DnrJ EryC1 family K02805 - 2.6.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 390.0
HFD2_k127_4658201_1 hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000001616 249.0
HFD2_k127_4658201_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000113 127.0
HFD2_k127_4746830_0 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 496.0
HFD2_k127_4746830_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 419.0
HFD2_k127_4746830_10 FMN-binding domain protein - - - 0.00000000000000000000001687 106.0
HFD2_k127_4746830_11 Histone H1-like protein Hc1 - - - 0.000000000000007407 76.0
HFD2_k127_4746830_2 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 349.0
HFD2_k127_4746830_3 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 295.0
HFD2_k127_4746830_4 PFAM Iron permease FTR1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001042 263.0
HFD2_k127_4746830_5 unfolded protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009429 259.0
HFD2_k127_4746830_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000004827 183.0
HFD2_k127_4746830_7 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000002003 142.0
HFD2_k127_4746830_8 - - - - 0.000000000000000000000000331 111.0
HFD2_k127_4746830_9 Pfam:DUF59 - - - 0.000000000000000000000001909 110.0
HFD2_k127_4746866_0 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 404.0
HFD2_k127_4746866_1 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001314 263.0
HFD2_k127_4746866_2 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.000000000000000000000000002537 117.0
HFD2_k127_4781280_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 467.0
HFD2_k127_4781280_1 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002246 279.0
HFD2_k127_4781280_10 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000003204 97.0
HFD2_k127_4781280_11 - - - - 0.000001271 57.0
HFD2_k127_4781280_2 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000000000000003776 218.0
HFD2_k127_4781280_3 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.0000000000000000000000000000000000000000000002583 177.0
HFD2_k127_4781280_4 regulation of single-species biofilm formation K02342,K03763,K13573 - 2.7.7.7 0.00000000000000000000000000000000000000000003073 171.0
HFD2_k127_4781280_5 biotin transmembrane transporter activity K03523 - - 0.0000000000000000000000000000000006105 137.0
HFD2_k127_4781280_6 COG1246 N-acetylglutamate synthase and related acetyltransferases K00619 - 2.3.1.1 0.0000000000000000000000001166 113.0
HFD2_k127_4781280_7 3-demethylubiquinone-9 3-O-methyltransferase activity K03428 - 2.1.1.11 0.0000000000000000000003194 109.0
HFD2_k127_4781280_8 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.0000000000000000000008137 101.0
HFD2_k127_4781280_9 RecX family K03565 - - 0.000000000000000000002806 107.0
HFD2_k127_4819178_0 cellulose binding - - - 4.33e-222 693.0
HFD2_k127_4819178_1 UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 523.0
HFD2_k127_4819178_2 Belongs to the PdaD family K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 319.0
HFD2_k127_4819178_3 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.0000000000000000000000000000000000000003764 150.0
HFD2_k127_4819178_4 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 - 0.0000000000000000000000000000000000001081 143.0
HFD2_k127_4819178_5 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 GO:0003674,GO:0003824,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 0.0005538 45.0
HFD2_k127_4844582_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 539.0
HFD2_k127_4844582_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008504 339.0
HFD2_k127_4929966_0 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 472.0
HFD2_k127_4929966_1 cobalamin binding K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 339.0
HFD2_k127_4929966_2 cobalamin binding K00548 - 2.1.1.13 0.00000000000000000000569 94.0
HFD2_k127_4929966_3 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.000000000001861 72.0
HFD2_k127_4931141_0 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 413.0
HFD2_k127_4931141_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001541 276.0
HFD2_k127_4931141_2 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000002071 211.0
HFD2_k127_4931141_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000002167 183.0
HFD2_k127_4931141_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000002985 165.0
HFD2_k127_4931141_5 peptidase M20 - - - 0.0000000000000000000000000000000000000000001301 161.0
HFD2_k127_4931141_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000008906 100.0
HFD2_k127_4957244_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 563.0
HFD2_k127_4957244_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 539.0
HFD2_k127_4957244_2 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006027 289.0
HFD2_k127_4957244_3 PFAM single-strand binding protein Primosomal replication protein n K03111 - - 0.000000000000000000000000000000000000000000000703 170.0
HFD2_k127_4957244_4 cobalamin-transporting ATPase activity K02014,K16092 - - 0.0000000000000000000000000000004432 140.0
HFD2_k127_4957244_5 amine dehydrogenase activity - - - 0.00000000000000000000002589 111.0
HFD2_k127_4972903_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 580.0
HFD2_k127_4972903_1 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009833 394.0
HFD2_k127_4972903_2 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 320.0
HFD2_k127_4972903_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000007757 194.0
HFD2_k127_4972903_4 cellulose binding - - - 0.0000000000000000000000000000000000000000000000001312 200.0
HFD2_k127_4972903_5 cellulose binding - - - 0.000000000000000000000000000000000004854 158.0
HFD2_k127_4972903_6 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000001697 146.0
HFD2_k127_4972903_7 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000002631 108.0
HFD2_k127_5002588_0 Cytochrome C biogenesis protein transmembrane region K06196,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000001116 255.0
HFD2_k127_5002588_1 single-stranded DNA binding K03111 - - 0.0000000000000000000000000000000000000000000000000000000000001941 215.0
HFD2_k127_5002588_2 rRNA binding K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000003458 193.0
HFD2_k127_5002588_3 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000003708 119.0
HFD2_k127_5002588_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000003132 104.0
HFD2_k127_5002588_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000001705 88.0
HFD2_k127_5002588_6 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000001435 66.0
HFD2_k127_515389_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 454.0
HFD2_k127_515389_1 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002623 251.0
HFD2_k127_515389_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000006061 184.0
HFD2_k127_515389_3 aminopeptidase activity K19701 - 3.4.11.10,3.4.11.6 0.00000000000000000001671 102.0
HFD2_k127_515389_4 peptidyl-tyrosine sulfation - - - 0.00000001363 66.0
HFD2_k127_515389_5 Tetratricopeptide repeat - - - 0.00002364 57.0
HFD2_k127_5167918_0 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 582.0
HFD2_k127_5167918_1 undecaprenyl-phosphate glucose phosphotransferase activity K03606,K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 526.0
HFD2_k127_5167918_10 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000000006661 169.0
HFD2_k127_5167918_11 Sulfatase-modifying factor enzyme 1 K01176,K01206,K01218,K01219,K01224 - 3.2.1.1,3.2.1.51,3.2.1.78,3.2.1.81,3.2.1.89 0.0000000000000000000000000000000000000462 166.0
HFD2_k127_5167918_12 Thioesterase K07107 - - 0.00000000000000000000000000000001224 131.0
HFD2_k127_5167918_13 domain protein K07004,K09955,K16915,K20276 - - 0.0000000000000000000000003798 124.0
HFD2_k127_5167918_14 COG NOG04032 non supervised orthologous group K17624 - 3.2.1.97 0.000000006721 70.0
HFD2_k127_5167918_15 Trm112p-like protein K09791 - - 0.0000001793 57.0
HFD2_k127_5167918_2 malonyl-CoA biosynthetic process K01962,K01963 GO:0001676,GO:0003674,GO:0003824,GO:0003989,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0042759,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494,GO:1990234 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006201 496.0
HFD2_k127_5167918_3 translation release factor activity K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007332 438.0
HFD2_k127_5167918_4 polysaccharide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 394.0
HFD2_k127_5167918_5 PFAM aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 321.0
HFD2_k127_5167918_6 Protein of unknown function (DUF1385) K09153 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007792 306.0
HFD2_k127_5167918_7 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004306 284.0
HFD2_k127_5167918_8 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000006409 247.0
HFD2_k127_5167918_9 MafB19-like deaminase K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000004459 186.0
HFD2_k127_5184797_0 mRNA catabolic process K18682 - - 9.568e-214 675.0
HFD2_k127_5184797_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.427e-210 672.0
HFD2_k127_5184797_2 glutamine phosphoribosylpyrophosphate amidotransferase K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 574.0
HFD2_k127_5184797_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 382.0
HFD2_k127_5184797_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K02549,K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 4.2.1.113,5.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008474 382.0
HFD2_k127_5184797_5 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000001556 230.0
HFD2_k127_5184797_6 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000000003205 148.0
HFD2_k127_5184797_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.00000000000000000000002478 106.0
HFD2_k127_5184797_8 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000009527 51.0
HFD2_k127_5193004_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 8.084e-201 642.0
HFD2_k127_5193004_2 RNA pseudouridylate synthase K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000383 197.0
HFD2_k127_5193004_3 nUDIX hydrolase K01515,K03574,K08310 - 3.6.1.13,3.6.1.55,3.6.1.67 0.000000000000000000000003383 111.0
HFD2_k127_5200100_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 566.0
HFD2_k127_5200100_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 322.0
HFD2_k127_5200100_2 Arabinose efflux permease family protein - - - 0.00000000000000000000000000001923 130.0
HFD2_k127_5226790_0 Peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 297.0
HFD2_k127_5226790_1 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.000000000000000000000000000000000000000000000000000000002839 209.0
HFD2_k127_5226790_2 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000002712 149.0
HFD2_k127_5233117_0 Sulfate permease family K01673,K03321 - 4.2.1.1 1.99e-208 662.0
HFD2_k127_5233117_1 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K19591,K22491 - - 0.000000000000000000000000000000000000003317 156.0
HFD2_k127_5233117_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000007383 163.0
HFD2_k127_5233117_3 Catalyzes the dephosphorylation of D,L-glyceraldehyde 3- phosphate in vitro K07025 - - 0.00000000000000000000000000000000003584 144.0
HFD2_k127_5233117_4 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000001317 122.0
HFD2_k127_5233117_5 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.00000000000000000000000000003453 121.0
HFD2_k127_5233117_7 phosphorelay signal transduction system - - - 0.000000000000000001875 94.0
HFD2_k127_5238739_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 485.0
HFD2_k127_5238739_1 Bacterial extracellular solute-binding protein, family 7 K11688,K21395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 339.0
HFD2_k127_5238739_2 Glycosyl hydrolase-like 10 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 328.0
HFD2_k127_5238739_3 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000007714 202.0
HFD2_k127_5238739_4 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.000000000000000000000004512 110.0
HFD2_k127_5238739_5 Belongs to the peptidase S8 family - - - 0.00000000000000000119 102.0
HFD2_k127_5238739_6 nucleotide catabolic process - - - 0.000000000000000003581 101.0
HFD2_k127_5238739_7 peptidyl-tyrosine sulfation - - - 0.00000001795 57.0
HFD2_k127_5238739_8 - - - - 0.00005348 53.0
HFD2_k127_5309357_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 438.0
HFD2_k127_5309357_1 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 427.0
HFD2_k127_5309357_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 436.0
HFD2_k127_5309357_3 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007789 379.0
HFD2_k127_5309357_4 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000002404 155.0
HFD2_k127_5309357_5 deoxyhypusine monooxygenase activity K05385 - - 0.00000000000000000000000000002439 135.0
HFD2_k127_5309357_7 RHS repeat-associated core domain - - - 0.00000001668 66.0
HFD2_k127_5311419_0 Sigma-54 interaction domain K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000964 616.0
HFD2_k127_5311419_1 antibiotic biosynthetic process K01434,K07116 - 3.5.1.11,3.5.1.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 586.0
HFD2_k127_5311419_2 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008341 438.0
HFD2_k127_5311419_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 427.0
HFD2_k127_5311419_4 NAD+ binding K12410 GO:0000726,GO:0003674,GO:0003824,GO:0003953,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006464,GO:0006471,GO:0006476,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016787,GO:0016798,GO:0016799,GO:0019213,GO:0019538,GO:0030312,GO:0033554,GO:0033558,GO:0034641,GO:0034979,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070213,GO:0071214,GO:0071478,GO:0071479,GO:0071704,GO:0071944,GO:0090304,GO:0098732,GO:0104004,GO:0140096,GO:1901360,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 286.0
HFD2_k127_5311419_5 Dihydrouridine synthase (Dus) K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000005939 261.0
HFD2_k127_5311419_6 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000392 250.0
HFD2_k127_5311419_7 - - - - 0.0000000000000000000000000000000000000000000000000000000001273 214.0
HFD2_k127_5333303_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.651e-279 873.0
HFD2_k127_5333303_1 polyribonucleotide nucleotidyltransferase activity K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 308.0
HFD2_k127_5333303_2 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 293.0
HFD2_k127_5333303_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000009167 118.0
HFD2_k127_5333303_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000009561 113.0
HFD2_k127_5434434_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000886 589.0
HFD2_k127_5434434_1 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 497.0
HFD2_k127_5434434_10 synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000001056 181.0
HFD2_k127_5434434_11 oxidoreductase activity K17745 - 1.1.1.325 0.0000000000000000000000000000000000000000000008383 176.0
HFD2_k127_5434434_12 Predicted periplasmic lipoprotein (DUF2279) - - - 0.000000000000000000000000001454 126.0
HFD2_k127_5434434_13 oxidoreductase FAD NAD(P)-binding K00523,K00528 - 1.17.1.1,1.18.1.2,1.19.1.1 0.000000000687 70.0
HFD2_k127_5434434_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 383.0
HFD2_k127_5434434_3 gtp cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004828 271.0
HFD2_k127_5434434_4 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000006131 259.0
HFD2_k127_5434434_5 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000004591 224.0
HFD2_k127_5434434_6 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000000000000000000000000000000000000796 208.0
HFD2_k127_5434434_7 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000004827 211.0
HFD2_k127_5434434_8 AhpC/TSA family K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000008253 194.0
HFD2_k127_5434434_9 AhpC/TSA family K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000007189 195.0
HFD2_k127_5447571_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 330.0
HFD2_k127_5447571_1 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 301.0
HFD2_k127_5447571_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000003541 249.0
HFD2_k127_5447571_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000187 124.0
HFD2_k127_5447571_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000005531 130.0
HFD2_k127_5460866_0 Nickel-dependent hydrogenase - - - 6.244e-213 668.0
HFD2_k127_5460866_1 coenzyme F420 hydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001721 274.0
HFD2_k127_5460866_2 Belongs to the carbamoyltransferase HypF family K04656 - - 0.000000000000000000000000000000000000000007221 159.0
HFD2_k127_5460866_3 Hydrogenase maturation protease - - - 0.00000000000000000000000000000000000008971 147.0
HFD2_k127_5460866_4 Hydrogenase/urease nickel incorporation, metallochaperone, hypA - - - 0.0000000000001291 73.0
HFD2_k127_5487705_0 protein transport K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 384.0
HFD2_k127_5487705_1 rRNA binding K02988 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000001085 246.0
HFD2_k127_5487705_2 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000000001983 231.0
HFD2_k127_5487705_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000001752 173.0
HFD2_k127_5487705_4 rRNA binding K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.0000000000000000000000000000000000000006736 157.0
HFD2_k127_5487705_5 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000002469 129.0
HFD2_k127_5487705_6 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000000009238 101.0
HFD2_k127_5487705_7 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000001002 86.0
HFD2_k127_5491280_0 Predicted membrane protein (DUF2339) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 435.0
HFD2_k127_5491280_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 409.0
HFD2_k127_5491280_2 Multidrug transporter K08161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001035 293.0
HFD2_k127_5504295_0 PFAM HypF finger K04656 - - 2.341e-235 743.0
HFD2_k127_5504295_1 hydrogenase expression formation protein K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 512.0
HFD2_k127_5504295_2 AIR synthase related protein, C-terminal domain K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 445.0
HFD2_k127_5504295_3 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002556 248.0
HFD2_k127_5504295_4 Bacterial regulatory proteins, crp family K10914 - - 0.0000000000000000000000000000000000000000000002044 175.0
HFD2_k127_5504295_5 glutamate dehydrogenase [NAD(P)+] activity K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 0.000000000000000000000000000006746 124.0
HFD2_k127_5504295_6 Hydrogenase expression formation protein K04653 - - 0.0000000000000000007525 91.0
HFD2_k127_5507728_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 539.0
HFD2_k127_5507728_1 amino acid transport K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 486.0
HFD2_k127_5507728_10 PspC domain - - - 0.000000000000000000000000000000000005008 146.0
HFD2_k127_5507728_2 Cys/Met metabolism PLP-dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 341.0
HFD2_k127_5507728_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 336.0
HFD2_k127_5507728_4 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008873 328.0
HFD2_k127_5507728_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005376 247.0
HFD2_k127_5507728_6 cytoplasmic translational termination K02838 GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000003964 220.0
HFD2_k127_5507728_7 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0000000000000000000000000000000000000000005601 160.0
HFD2_k127_5507728_8 mRNA binding K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000855 158.0
HFD2_k127_5507728_9 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000005879 157.0
HFD2_k127_5530887_0 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009468 623.0
HFD2_k127_5530887_1 PFAM glycosyl transferase group 1 K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 583.0
HFD2_k127_5530887_10 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.00000000000000000000000000000000000000000000000000000002818 202.0
HFD2_k127_5530887_11 coenzyme F420 hydrogenase activity - - - 0.0000000000000000000000000000000000000000000000008197 177.0
HFD2_k127_5530887_12 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000004888 153.0
HFD2_k127_5530887_13 AAA domain - - - 0.000000000000000000000000001346 128.0
HFD2_k127_5530887_14 cell adhesion involved in biofilm formation K20276 - - 0.00000000000000000000000001257 128.0
HFD2_k127_5530887_15 Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000001068 85.0
HFD2_k127_5530887_16 - - - - 0.000000000006191 76.0
HFD2_k127_5530887_2 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K16950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 473.0
HFD2_k127_5530887_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02022,K16922,K20345 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004941 421.0
HFD2_k127_5530887_4 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 380.0
HFD2_k127_5530887_5 Uncharacterized protein conserved in bacteria (DUF2130) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 308.0
HFD2_k127_5530887_6 beta-lactamase activity K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008685 273.0
HFD2_k127_5530887_7 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000009149 226.0
HFD2_k127_5530887_8 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000005819 207.0
HFD2_k127_5530887_9 response regulator - - - 0.000000000000000000000000000000000000000000000000000000001764 210.0
HFD2_k127_5620466_0 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 2.921e-231 741.0
HFD2_k127_5620466_1 Prolyl oligopeptidase family - - - 3.871e-213 683.0
HFD2_k127_5620466_10 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001147 278.0
HFD2_k127_5620466_11 deaminated base DNA N-glycosylase activity K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000002781 263.0
HFD2_k127_5620466_12 PFAM YicC domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008177 261.0
HFD2_k127_5620466_13 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000003019 238.0
HFD2_k127_5620466_14 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000848 183.0
HFD2_k127_5620466_15 s1 p1 nuclease - - - 0.00000000000000000000000000000008996 142.0
HFD2_k127_5620466_16 Cell shape-determining protein MreC K03570 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963 - 0.00000000000000000000000000000296 131.0
HFD2_k127_5620466_17 Belongs to the peptidase S8 family - - - 0.0000000000000000004276 102.0
HFD2_k127_5620466_18 rod shape-determining protein MreD K03571 - - 0.00000000000000001009 91.0
HFD2_k127_5620466_19 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits - - - 0.0000006421 59.0
HFD2_k127_5620466_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 584.0
HFD2_k127_5620466_3 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000805 581.0
HFD2_k127_5620466_4 Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 544.0
HFD2_k127_5620466_5 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 540.0
HFD2_k127_5620466_6 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 504.0
HFD2_k127_5620466_7 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 370.0
HFD2_k127_5620466_8 peptidoglycan glycosyltransferase activity K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 344.0
HFD2_k127_5620466_9 dUTP biosynthetic process K01494,K01520 - 3.5.4.13,3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 288.0
HFD2_k127_5639683_0 Glycine cleavage system P-protein K00281 - 1.4.4.2 0.0 1236.0
HFD2_k127_5639683_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 8.382e-203 640.0
HFD2_k127_5639683_2 translation elongation factor activity K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000005012 181.0
HFD2_k127_5639683_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000009093 172.0
HFD2_k127_5639683_4 ligase activity, forming carbon-carbon bonds K00627,K01571,K02160 - 2.3.1.12,4.1.1.3 0.00000000000000000000000000000000000000003707 156.0
HFD2_k127_5656608_0 Belongs to the glycosyl hydrolase 28 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005412 489.0
HFD2_k127_5656608_1 Domain of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 413.0
HFD2_k127_5656608_2 pectinesterase activity K10117 - - 0.00000000000000000000000000000000000001559 167.0
HFD2_k127_5656608_3 metallopeptidase activity K01186 - 3.2.1.18 0.0000000000000000000000000004192 133.0
HFD2_k127_5656608_4 Sulfatase-modifying factor enzyme 1 K01176,K01206,K01218,K01219,K01224 - 3.2.1.1,3.2.1.51,3.2.1.78,3.2.1.81,3.2.1.89 0.00000000000000000000000002997 127.0
HFD2_k127_5656608_5 nucleotide catabolic process - - - 0.0000000000000000000000002949 107.0
HFD2_k127_5656608_6 cellulose binding K00505 - 1.14.18.1 0.0000000000000002509 94.0
HFD2_k127_5656608_7 self proteolysis K04771 - 3.4.21.107 0.000000000000005392 77.0
HFD2_k127_5702213_0 ATP-dependent peptidase activity K01338 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004175,GO:0004176,GO:0004252,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009408,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0017171,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051603,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.4.21.53 2.238e-199 628.0
HFD2_k127_5702213_1 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 412.0
HFD2_k127_5702213_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000117 185.0
HFD2_k127_5706125_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.0 1173.0
HFD2_k127_5706125_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 6.712e-206 661.0
HFD2_k127_5706125_2 glutamate dehydrogenase [NAD(P)+] activity K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 467.0
HFD2_k127_5706125_3 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 359.0
HFD2_k127_5706125_4 metallophosphoesterase K07096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 329.0
HFD2_k127_5706125_5 esterase - - - 0.000001557 62.0
HFD2_k127_5740312_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 6.704e-199 631.0
HFD2_k127_5740312_1 PFAM metallophosphoesterase K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001766 259.0
HFD2_k127_5745407_0 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 388.0
HFD2_k127_5745407_1 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009068 362.0
HFD2_k127_5745407_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000001277 171.0
HFD2_k127_5745407_3 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000001531 109.0
HFD2_k127_5745407_4 Thioesterase-like superfamily K07107 - - 0.00000000000002835 79.0
HFD2_k127_5745407_5 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000003188 70.0
HFD2_k127_5763940_0 Protein of unknown function, DUF255 K06888 - - 6.491e-221 709.0
HFD2_k127_5763940_1 adenosylhomocysteinase activity K01251 - 3.3.1.1 1.058e-210 661.0
HFD2_k127_5763940_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 445.0
HFD2_k127_5763940_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 374.0
HFD2_k127_5763940_4 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001587 276.0
HFD2_k127_5763940_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K02652,K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000009895 156.0
HFD2_k127_5783981_0 (ABC) transporter K06147,K18889 - - 5.482e-196 627.0
HFD2_k127_5783981_1 seryl-tRNA synthetase K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009364 501.0
HFD2_k127_5783981_2 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 343.0
HFD2_k127_5783981_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 327.0
HFD2_k127_5783981_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714,K21062 - 3.5.4.22,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 317.0
HFD2_k127_5783981_5 (ABC) transporter K06147,K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001096 262.0
HFD2_k127_5783981_6 DNA Methylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001446 269.0
HFD2_k127_5783981_7 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000002365 228.0
HFD2_k127_5783981_8 pfkB family carbohydrate kinase K00852,K00856 - 2.7.1.15,2.7.1.20 0.0000000232 65.0
HFD2_k127_5783981_9 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814,K01817,K11755 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0033554,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0050896,GO:0051716,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31,5.3.1.16,5.3.1.24 0.00000003778 56.0
HFD2_k127_5834719_0 Associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008344 505.0
HFD2_k127_5834719_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 451.0
HFD2_k127_5834719_10 RNA recognition motif - - - 0.000000000000007758 76.0
HFD2_k127_5834719_12 Oxygen tolerance - - - 0.00002069 51.0
HFD2_k127_5834719_2 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 412.0
HFD2_k127_5834719_3 Von Willebrand factor type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009849 399.0
HFD2_k127_5834719_4 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 389.0
HFD2_k127_5834719_5 Von Willebrand factor type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 364.0
HFD2_k127_5834719_6 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000004601 193.0
HFD2_k127_5834719_7 protein trimerization - - - 0.0000000000000000000000000000000000000000006017 167.0
HFD2_k127_5834719_8 PFAM SPFH domain Band 7 family - - - 0.00000000000000000000000000000000003003 146.0
HFD2_k127_5834719_9 RNA-binding protein - - - 0.000000000000000000005054 97.0
HFD2_k127_5839284_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.28e-248 777.0
HFD2_k127_5839284_1 Belongs to the aldehyde dehydrogenase family K00140,K22187 - 1.2.1.18,1.2.1.27 2.042e-213 674.0
HFD2_k127_5839284_10 Transketolase, pyrimidine binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 362.0
HFD2_k127_5839284_11 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 328.0
HFD2_k127_5839284_12 PFAM Transketolase K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009251 297.0
HFD2_k127_5839284_13 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001302 275.0
HFD2_k127_5839284_14 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000001874 261.0
HFD2_k127_5839284_15 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000001158 262.0
HFD2_k127_5839284_16 lipoprotein biosynthetic process K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000002348 235.0
HFD2_k127_5839284_17 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000008632 227.0
HFD2_k127_5839284_18 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000003971 192.0
HFD2_k127_5839284_19 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.0000000000000000000000000000000000000000000000009766 178.0
HFD2_k127_5839284_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 550.0
HFD2_k127_5839284_20 Protein of unknown function (DUF1428) - - - 0.00000000000000000000000000000000000000000001813 166.0
HFD2_k127_5839284_21 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000004899 154.0
HFD2_k127_5839284_22 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.00000000000000000000000000007049 125.0
HFD2_k127_5839284_23 amino acid activation for nonribosomal peptide biosynthetic process K05996 - 3.4.17.18 0.0000000000000000000001717 115.0
HFD2_k127_5839284_24 glutaredoxin 2 - - - 0.00000000000002274 78.0
HFD2_k127_5839284_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821,K03918,K07250,K13524 - 2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22,2.6.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 530.0
HFD2_k127_5839284_4 Domain in cystathionine beta-synthase and other proteins. K01697 - 4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 489.0
HFD2_k127_5839284_5 Sigma-70 region 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008226 471.0
HFD2_k127_5839284_6 cystathionine gamma-synthase activity K01739,K01758,K01760,K01761 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004121,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 471.0
HFD2_k127_5839284_7 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 462.0
HFD2_k127_5839284_8 serine-type endopeptidase activity K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 415.0
HFD2_k127_5839284_9 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 432.0
HFD2_k127_5848461_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.205e-317 984.0
HFD2_k127_5848461_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 497.0
HFD2_k127_5848461_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 375.0
HFD2_k127_5848461_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 320.0
HFD2_k127_5848461_4 COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 303.0
HFD2_k127_5848461_5 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004811 273.0
HFD2_k127_5848461_6 ABC transporter permease K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001386 269.0
HFD2_k127_5848461_7 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000004281 244.0
HFD2_k127_5856199_0 Aldehyde dehydrogenase family K00130 - 1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 418.0
HFD2_k127_5856199_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000204 279.0
HFD2_k127_5856199_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000001048 229.0
HFD2_k127_5856199_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000004903 233.0
HFD2_k127_5856199_4 cellular water homeostasis K05802,K16052 - - 0.00000000000000000000000000000000000000000000000000004059 203.0
HFD2_k127_5856199_5 nUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000001971 135.0
HFD2_k127_5856199_6 dehydratase K01724 - 4.2.1.96 0.0000000000000000000004096 100.0
HFD2_k127_5856199_7 HemY protein - - - 0.0000000005604 68.0
HFD2_k127_5881265_0 usher protein - - - 0.000000000000000000000000000000000000000000000000000000000002858 236.0
HFD2_k127_5881265_1 endo-1,4-beta-xylanase activity K01181,K21606 - 3.2.1.202,3.2.1.8 0.000000000000000000001401 110.0
HFD2_k127_5881265_2 pilus organization K12132 - 2.7.11.1 0.0000000000000003083 89.0
HFD2_k127_5881265_3 cellulose binding - - - 0.00000000001423 74.0
HFD2_k127_5881265_4 hydrolase activity - GO:0001101,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0007498,GO:0008150,GO:0009888,GO:0010033,GO:0010883,GO:0012505,GO:0032502,GO:0032526,GO:0032879,GO:0033993,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0048856,GO:0050789,GO:0050896,GO:0065007,GO:0065008,GO:1901700,GO:1905952 - 0.00000000002873 65.0
HFD2_k127_5932265_0 PFAM glycosyl transferase family 20 K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 1.438e-263 831.0
HFD2_k127_5932265_1 ATP-dependent helicase K03579 - 3.6.4.13 1.449e-260 827.0
HFD2_k127_5932265_10 E1-E2 ATPase K17686 - 3.6.3.54 0.00000000001044 67.0
HFD2_k127_5932265_11 pfam yhs - - - 0.00000000006714 64.0
HFD2_k127_5932265_2 cyclic 2,3-diphosphoglycerate synthetase activity K05716 - - 2.521e-195 617.0
HFD2_k127_5932265_3 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 379.0
HFD2_k127_5932265_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006684 336.0
HFD2_k127_5932265_5 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 302.0
HFD2_k127_5932265_6 Transposase - - - 0.00000000000000002916 93.0
HFD2_k127_5932265_7 - - - - 0.0000000000000002856 86.0
HFD2_k127_5932265_8 - - - - 0.0000000000001284 74.0
HFD2_k127_5932265_9 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000006383 68.0
HFD2_k127_5942366_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 512.0
HFD2_k127_5942366_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 437.0
HFD2_k127_5942366_11 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000004451 135.0
HFD2_k127_5942366_12 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000003294 93.0
HFD2_k127_5942366_13 domain, Protein - - - 0.0000000000000000004013 105.0
HFD2_k127_5942366_15 Subtilase family - - - 0.0001373 48.0
HFD2_k127_5942366_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 411.0
HFD2_k127_5942366_3 exonuclease activity K16899 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 425.0
HFD2_k127_5942366_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 423.0
HFD2_k127_5942366_5 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 391.0
HFD2_k127_5942366_6 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005103 252.0
HFD2_k127_5942366_7 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000429 230.0
HFD2_k127_5942366_8 nucleotidyltransferase activity K04095 - - 0.0000000000000000000000000000000000000000000000000000000001916 209.0
HFD2_k127_5945813_0 cellulose binding - - - 8.428e-240 763.0
HFD2_k127_5945813_1 Domain of unknown function DUF87 K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 396.0
HFD2_k127_5945813_2 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 387.0
HFD2_k127_5945813_3 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000000000000000000000008668 166.0
HFD2_k127_5945813_4 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000000000003433 143.0
HFD2_k127_5945813_5 Belongs to the peptidase S8 family - - - 0.0000000000000000000001015 102.0
HFD2_k127_5945813_6 PFAM IS1 transposase K07480 - - 0.0000000000000008445 79.0
HFD2_k127_5974474_0 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001564 265.0
HFD2_k127_5974474_1 - - - - 0.000000000000000000000000000003017 124.0
HFD2_k127_5974474_2 Thioesterase domain - - - 0.00000000000000000000000000124 123.0
HFD2_k127_5985116_0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639,K00652 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 532.0
HFD2_k127_5985116_1 transcription antitermination K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000928 501.0
HFD2_k127_5985116_10 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000003963 188.0
HFD2_k127_5985116_11 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000000000000479 182.0
HFD2_k127_5985116_12 lysyltransferase activity K07027 - - 0.0000000000000000000000000000000000000000000000005412 190.0
HFD2_k127_5985116_13 Peptidase M56 - - - 0.000000000000000000000000000001977 137.0
HFD2_k127_5985116_14 50S ribosomal protein L31 K02909 - - 0.000000000000000000000000006666 112.0
HFD2_k127_5985116_15 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000005859 103.0
HFD2_k127_5985116_16 iron-sulfur cluster assembly - - - 0.000000000000000004489 97.0
HFD2_k127_5985116_17 - K01406 - 3.4.24.40 0.0001851 48.0
HFD2_k127_5985116_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 416.0
HFD2_k127_5985116_3 Zinc-binding dehydrogenase K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 366.0
HFD2_k127_5985116_4 ftsk spoiiie K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 335.0
HFD2_k127_5985116_5 glucosamine-1-phosphate N-acetyltransferase activity K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 309.0
HFD2_k127_5985116_6 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005346 288.0
HFD2_k127_5985116_7 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000009989 262.0
HFD2_k127_5985116_8 Cell division ATP-binding protein ftsE K09812 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001887 254.0
HFD2_k127_5985116_9 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000001188 222.0
HFD2_k127_5986154_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1060.0
HFD2_k127_5986154_1 Sodium/hydrogen exchanger family K11105 - - 1.246e-197 629.0
HFD2_k127_5986154_2 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000004744 191.0
HFD2_k127_5986154_3 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.00000000000000000000000001671 119.0
HFD2_k127_5986154_4 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000001207 79.0
HFD2_k127_5986154_5 Domain of unknown function (DUF4440) - - - 0.000001045 55.0
HFD2_k127_601416_0 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002983 232.0
HFD2_k127_601416_1 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000002217 150.0
HFD2_k127_601416_2 Phospholipid methyltransferase - - - 0.00000000000000000000000000000001628 136.0
HFD2_k127_601416_3 transglutaminase - - - 0.00000000000004106 78.0
HFD2_k127_6054655_0 Hep Hag repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000004979 255.0
HFD2_k127_6054655_1 SprB repeat - - - 0.00000000000000000000000000000000000000000000000000000003101 209.0
HFD2_k127_6054655_2 AAA domain - - - 0.0000000000000000001955 103.0
HFD2_k127_6054655_3 6-phosphogluconolactonase activity - - - 0.00000000000000003011 93.0
HFD2_k127_6061624_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 6.665e-291 906.0
HFD2_k127_6061624_1 (ABC) transporter K02021,K06147,K06148,K11085 - - 6.374e-221 706.0
HFD2_k127_6061624_10 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000001201 153.0
HFD2_k127_6061624_11 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000001481 142.0
HFD2_k127_6061624_12 Domain of unknown function (DUF1844) - - - 0.0000000000000000000004727 98.0
HFD2_k127_6061624_13 O-Antigen ligase - - - 0.000000000000000000002446 108.0
HFD2_k127_6061624_14 - - - - 0.000000000000000000773 96.0
HFD2_k127_6061624_15 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000003139 85.0
HFD2_k127_6061624_16 phosphatidylinositol metabolic process K13671 - - 0.00000000001924 76.0
HFD2_k127_6061624_2 Fe-S oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 563.0
HFD2_k127_6061624_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 525.0
HFD2_k127_6061624_4 Glycosyl transferase, family 2 K12984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001393 266.0
HFD2_k127_6061624_5 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760,K00939,K15780 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,2.7.4.3,6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000001101 229.0
HFD2_k127_6061624_6 isomerase activity K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000422 225.0
HFD2_k127_6061624_7 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000019 222.0
HFD2_k127_6061624_8 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000007667 204.0
HFD2_k127_6061624_9 dolichyl monophosphate biosynthetic process K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000002884 203.0
HFD2_k127_6067370_0 Belongs to the ATCase OTCase family K00608,K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008676 451.0
HFD2_k127_6067370_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 458.0
HFD2_k127_6067370_3 uracil phosphoribosyltransferase activity K02825 GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000002953 231.0
HFD2_k127_6067370_4 nucleotide catabolic process - - - 0.000000000000000008021 98.0
HFD2_k127_6067370_5 snoRNA binding - - - 0.000000000006079 70.0
HFD2_k127_6067370_7 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000004424 76.0
HFD2_k127_6084821_0 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006687 253.0
HFD2_k127_6084821_1 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000357 145.0
HFD2_k127_6084821_2 Putative ATP-binding cassette K01992 - - 0.000000000000000000000000000000007064 147.0
HFD2_k127_6084821_4 Photosynthesis system II assembly factor YCF48 - - - 0.0000000000002966 83.0
HFD2_k127_6084821_5 NHL repeat - - - 0.000000001061 72.0
HFD2_k127_6090073_0 proton-transporting ATP synthase activity, rotational mechanism K02112 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 2.774e-241 752.0
HFD2_k127_6090073_1 mannose-1-phosphate guanylyltransferase activity K00971,K01840,K16011 - 2.7.7.13,5.3.1.8,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 406.0
HFD2_k127_6090073_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 331.0
HFD2_k127_6090073_3 ribose 5-phosphate isomerase B K00761,K01808 - 2.4.2.9,5.3.1.6 0.00000000000000000000000000000000000000000000000005584 185.0
HFD2_k127_6090073_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000009142 138.0
HFD2_k127_6090073_5 proton-transporting ATP synthase activity, rotational mechanism K02114 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000002315 127.0
HFD2_k127_6090073_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000005076 138.0
HFD2_k127_6090073_7 PFAM Lytic transglycosylase catalytic K08309 - - 0.00000000000000000106 92.0
HFD2_k127_6103655_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 565.0
HFD2_k127_6103655_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000624 250.0
HFD2_k127_6103655_2 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000002512 207.0
HFD2_k127_6103655_3 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000005913 190.0
HFD2_k127_6103655_4 - - - - 0.00000000000000000000000000000000000000000317 160.0
HFD2_k127_6103655_5 Cold shock protein K03704 - - 0.00000000000000000001208 93.0
HFD2_k127_6103655_6 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0009972 45.0
HFD2_k127_6150680_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005865 416.0
HFD2_k127_6150680_1 CYTH - - - 0.000000000000000003269 88.0
HFD2_k127_6155631_0 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 418.0
HFD2_k127_6155631_1 Sigma-54 interaction domain K11384 - - 0.0000000000000000000000000000000000000000000000000001389 201.0
HFD2_k127_6160254_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000004351 248.0
HFD2_k127_6160254_1 beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000005057 204.0
HFD2_k127_6160254_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000104 132.0
HFD2_k127_6160254_3 - - - - 0.000000000000000000000006332 111.0
HFD2_k127_6160254_4 pectinesterase activity - - - 0.0000000000000003198 89.0
HFD2_k127_6160254_5 Planctomycete cytochrome C - - - 0.0000000000002371 77.0
HFD2_k127_6160254_6 response regulator K02485,K03413,K07684 - - 0.00000001463 66.0
HFD2_k127_6218792_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1168.0
HFD2_k127_6218792_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 2.26e-197 631.0
HFD2_k127_6218792_2 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 340.0
HFD2_k127_6218792_3 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000541 214.0
HFD2_k127_6218792_4 cell envelope organization K05807,K08309 - - 0.000000000000000000000000000000000000000000000000000006075 200.0
HFD2_k127_6218792_5 acyl-coa hydrolase K01073 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 3.1.2.20 0.00000000000000000000000000000000000000000005578 167.0
HFD2_k127_6218792_6 ATPase activity K01990,K02193 - 3.6.3.41 0.00000000000000000000000000000000000000004277 168.0
HFD2_k127_6218792_7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000005717 135.0
HFD2_k127_6218792_8 Putative regulatory protein - - - 0.0000004804 57.0
HFD2_k127_623572_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0 1260.0
HFD2_k127_623572_1 Required for chromosome condensation and partitioning K03529 - - 2.463e-241 787.0
HFD2_k127_623572_10 PFAM ABC transporter transmembrane K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 409.0
HFD2_k127_623572_11 ATP-grasp domain K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 410.0
HFD2_k127_623572_12 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 407.0
HFD2_k127_623572_13 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity K00057 GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 378.0
HFD2_k127_623572_14 tRNA pseudouridine synthase activity K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 341.0
HFD2_k127_623572_15 beta-galactosidase activity K01190 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 353.0
HFD2_k127_623572_16 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 332.0
HFD2_k127_623572_17 triose-phosphate isomerase activity K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007048 297.0
HFD2_k127_623572_18 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004064 284.0
HFD2_k127_623572_19 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000001423 262.0
HFD2_k127_623572_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 8.466e-215 690.0
HFD2_k127_623572_20 Tetraacyldisaccharide-1-P 4'-kinase K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000004244 226.0
HFD2_k127_623572_21 L-methionine salvage from methylthioadenosine K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000002509 209.0
HFD2_k127_623572_22 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000002044 194.0
HFD2_k127_623572_23 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000003639 178.0
HFD2_k127_623572_24 acetyltransferase K18815 - 2.3.1.82 0.000000000000000000000000000000000000000001231 161.0
HFD2_k127_623572_25 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000001791 163.0
HFD2_k127_623572_26 DinB superfamily - - - 0.00000000000000000000000000000003769 137.0
HFD2_k127_623572_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K01876,K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 2.107e-205 649.0
HFD2_k127_623572_4 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 592.0
HFD2_k127_623572_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 538.0
HFD2_k127_623572_6 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 509.0
HFD2_k127_623572_7 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 494.0
HFD2_k127_623572_8 Delta-1-pyrroline-5-carboxylate dehydrogenase K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 428.0
HFD2_k127_623572_9 Zn-dependent protease with chaperone function K03799,K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 419.0
HFD2_k127_6239220_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 377.0
HFD2_k127_6239220_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001307 252.0
HFD2_k127_6239220_2 response to copper ion K07156 - - 0.000000000000000000000000000000000000000000000000000000000000000000164 251.0
HFD2_k127_6239220_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.0000000000000000000000004782 114.0
HFD2_k127_6239220_4 Sporulation and cell division repeat protein - - - 0.00000918 54.0
HFD2_k127_6253499_0 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 627.0
HFD2_k127_6253499_1 Flavin containing amine oxidoreductase K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008366 397.0
HFD2_k127_6253499_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 366.0
HFD2_k127_6253499_3 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000008037 164.0
HFD2_k127_6400771_0 Belongs to the aldehyde dehydrogenase family K22187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006147 483.0
HFD2_k127_6400771_1 major pilin protein fima - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 383.0
HFD2_k127_6400771_2 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000003629 261.0
HFD2_k127_6400771_3 Cadherin-like - - - 0.00000000000000000000000000008925 133.0
HFD2_k127_6400771_4 - - - - 0.00000000000000005046 93.0
HFD2_k127_6400771_5 Tetratricopeptide TPR_2 repeat protein - - - 0.0000005003 63.0
HFD2_k127_642434_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 6.81e-214 676.0
HFD2_k127_642434_1 Histidine kinase K07644 - 2.7.13.3 0.00000000000000000000000000000000000000001303 172.0
HFD2_k127_642434_2 anaphase-promoting complex binding - - - 0.00000000000000000001687 94.0
HFD2_k127_642434_3 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000138 76.0
HFD2_k127_6456266_0 CTP synthase activity K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 5.758e-231 734.0
HFD2_k127_6456266_1 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 597.0
HFD2_k127_6456266_10 Fibronectin type 3 domain - - - 0.0000000000000006578 93.0
HFD2_k127_6456266_2 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 371.0
HFD2_k127_6456266_3 Protein involved in outer membrane biogenesis K07289,K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004023 281.0
HFD2_k127_6456266_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000008896 252.0
HFD2_k127_6456266_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000006909 245.0
HFD2_k127_6456266_6 phosphatidate phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000001006 246.0
HFD2_k127_6456266_7 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000001361 171.0
HFD2_k127_6456266_8 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000897 155.0
HFD2_k127_6456266_9 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000009062 120.0
HFD2_k127_652054_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007267 539.0
HFD2_k127_652054_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 422.0
HFD2_k127_652054_2 Phage integrase, N-terminal SAM-like domain K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001295 267.0
HFD2_k127_652054_3 regulation of translation K03733,K05808,K05809 - - 0.0000000000001104 79.0
HFD2_k127_6522102_0 FAD linked oxidase domain protein K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 531.0
HFD2_k127_6522102_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase K15975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 439.0
HFD2_k127_6522102_10 Domain of unknown function (DUF4412) - - - 0.0000000000000001078 91.0
HFD2_k127_6522102_12 cell wall surface anchor family protein - - - 0.0003282 54.0
HFD2_k127_6522102_2 calcium- and calmodulin-responsive adenylate cyclase activity K06990,K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 399.0
HFD2_k127_6522102_3 Cysteine-rich domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006932 366.0
HFD2_k127_6522102_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 334.0
HFD2_k127_6522102_5 PFAM Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000216 254.0
HFD2_k127_6522102_6 palmitoyl-(protein) hydrolase activity K06999 - - 0.000000000000000000000000000000000000000009632 163.0
HFD2_k127_6522102_8 Iron-binding zinc finger CDGSH type - - - 0.00000000000000000000001749 106.0
HFD2_k127_6522102_9 Hep Hag repeat protein - - - 0.00000000000000000002504 107.0
HFD2_k127_6528954_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008888 559.0
HFD2_k127_6528954_1 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 560.0
HFD2_k127_6528954_10 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000164 227.0
HFD2_k127_6528954_11 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000001068 222.0
HFD2_k127_6528954_12 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000006992 213.0
HFD2_k127_6528954_13 ferredoxin-NADP+ reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000027 213.0
HFD2_k127_6528954_14 Insulinase (Peptidase family M16) - - - 0.000000000000000002383 88.0
HFD2_k127_6528954_15 PspC domain K03973 - - 0.0000000000001549 80.0
HFD2_k127_6528954_2 Zn_pept - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 536.0
HFD2_k127_6528954_3 Tryptophanyl-tRNA synthetase K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 501.0
HFD2_k127_6528954_4 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 424.0
HFD2_k127_6528954_5 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 420.0
HFD2_k127_6528954_6 Pyridine nucleotide-disulphide oxidoreductase K00384,K21567 - 1.18.1.2,1.19.1.1,1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 402.0
HFD2_k127_6528954_7 serine-type peptidase activity K01278 - 3.4.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 322.0
HFD2_k127_6528954_8 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000008828 231.0
HFD2_k127_6528954_9 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000008573 233.0
HFD2_k127_6539010_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 346.0
HFD2_k127_6539010_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 354.0
HFD2_k127_6539010_2 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 344.0
HFD2_k127_6539010_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000003246 199.0
HFD2_k127_6539010_4 Tetratricopeptide repeat - - - 0.00000001481 66.0
HFD2_k127_6539010_5 Transposase - - - 0.00000003695 62.0
HFD2_k127_6539010_6 transglycosylase K08307 - - 0.0008255 51.0
HFD2_k127_6539397_0 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002001 261.0
HFD2_k127_6539397_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000156 222.0
HFD2_k127_6539397_2 BNR Asp-box repeat - - - 0.00000000000000000000000000000000000000000000000000001843 217.0
HFD2_k127_6539397_3 PFAM Uncharacterised BCR, COG1649 K01186,K01197,K05988,K11931,K18197 - 3.2.1.11,3.2.1.18,3.2.1.35,4.2.2.23 0.0000000000000001874 95.0
HFD2_k127_6603399_0 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002265 231.0
HFD2_k127_6603399_1 PepSY-associated TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000209 239.0
HFD2_k127_6603399_2 GDP-mannose mannosyl hydrolase activity K01858,K03207,K03574 - 3.6.1.55,5.5.1.4 0.00000000000000000000000000000000000000000000000000009478 190.0
HFD2_k127_6603399_3 PFAM ABC transporter related K06861 - - 0.000000000000000000000000000000000000000000000000000182 187.0
HFD2_k127_6603399_4 ApaG domain K06195 - - 0.00000000000000000000000000000000000000001514 156.0
HFD2_k127_6603399_5 Serine aminopeptidase, S33 - - - 0.0000000000000000001755 93.0
HFD2_k127_6603399_6 Protein of unknown function (DUF1501) - - - 0.000001866 59.0
HFD2_k127_6603399_7 Belongs to the peptidase S8 family - - - 0.0004452 51.0
HFD2_k127_6716252_0 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 454.0
HFD2_k127_6735461_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 563.0
HFD2_k127_6735461_1 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 366.0
HFD2_k127_6754157_0 chaperone-mediated protein folding K00612 - - 0.000000000000000000000000000000000000000000000000000000000008145 223.0
HFD2_k127_6754157_1 phosphorelay signal transduction system - - - 0.00000000000000000005602 94.0
HFD2_k127_6754157_2 serine-type D-Ala-D-Ala carboxypeptidase activity K05366 - 2.4.1.129,3.4.16.4 0.000000000000000001232 89.0
HFD2_k127_6826312_0 Diguanylate cyclase - - - 0.000000000000001425 91.0
HFD2_k127_6826312_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000009971 59.0
HFD2_k127_6844359_0 ATP-dependent DNA helicase activity K03656,K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 570.0
HFD2_k127_6844359_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 515.0
HFD2_k127_6844359_2 PFAM Amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 489.0
HFD2_k127_6844359_3 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 430.0
HFD2_k127_6844359_4 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000353 129.0
HFD2_k127_6844359_5 lipopolysaccharide transmembrane transporter activity K03303,K07058 - - 0.000000000000000000007049 104.0
HFD2_k127_6844359_6 - - - - 0.000000000005112 74.0
HFD2_k127_6844359_8 Prokaryotic N-terminal methylation motif K10927 - - 0.0005324 49.0
HFD2_k127_6855307_0 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 377.0
HFD2_k127_6855307_1 cobalamin binding K22491 - - 0.000000000000000000000000000003323 132.0
HFD2_k127_6877403_0 exoribonuclease II activity K12573,K12585 - - 2.566e-196 636.0
HFD2_k127_6877403_1 NAD binding K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 589.0
HFD2_k127_6877403_10 glycerophosphodiester transmembrane transport K02026,K08715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006749 282.0
HFD2_k127_6877403_11 PFAM Short-chain dehydrogenase reductase SDR K00059,K00076 - 1.1.1.100,1.1.1.159 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000989 280.0
HFD2_k127_6877403_12 Carbonic anhydrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005216 264.0
HFD2_k127_6877403_13 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008199 272.0
HFD2_k127_6877403_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000002831 262.0
HFD2_k127_6877403_15 Inhibitor of apoptosis-promoting Bax1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006799 250.0
HFD2_k127_6877403_16 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000533 243.0
HFD2_k127_6877403_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000002371 197.0
HFD2_k127_6877403_18 2 iron, 2 sulfur cluster binding K00334,K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000002441 189.0
HFD2_k127_6877403_19 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000001258 195.0
HFD2_k127_6877403_2 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 568.0
HFD2_k127_6877403_20 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000001218 189.0
HFD2_k127_6877403_21 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000000000000000001086 172.0
HFD2_k127_6877403_22 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000005426 165.0
HFD2_k127_6877403_23 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.00000000000000000000000000000000000000001404 164.0
HFD2_k127_6877403_24 Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily K09457 - 1.7.1.13 0.00000000000000000000000000000000000004554 147.0
HFD2_k127_6877403_25 Protein of unknown function (DUF423) - - - 0.0000000000000000000000000000000000001793 145.0
HFD2_k127_6877403_26 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000000000000000000000001014 142.0
HFD2_k127_6877403_28 gluconolactonase activity - - - 0.000000000000000001233 102.0
HFD2_k127_6877403_29 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.0000000000000001253 81.0
HFD2_k127_6877403_3 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 481.0
HFD2_k127_6877403_30 Domain of unknown function (DUF309) K09763 - - 0.000000000000007493 85.0
HFD2_k127_6877403_31 Protein of unknown function (DUF1549) - - - 0.00000000004156 71.0
HFD2_k127_6877403_32 Adenylate cyclase - - - 0.000000168 65.0
HFD2_k127_6877403_4 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 456.0
HFD2_k127_6877403_5 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 407.0
HFD2_k127_6877403_6 ADP-L-glycero-beta-D-manno-heptose biosynthetic process K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 337.0
HFD2_k127_6877403_7 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 344.0
HFD2_k127_6877403_8 protein secretion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 331.0
HFD2_k127_6877403_9 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 293.0
HFD2_k127_6901002_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 564.0
HFD2_k127_6901002_1 Acetokinase family K00929 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0044424,GO:0044464,GO:0047761 2.7.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008128 330.0
HFD2_k127_6901002_2 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007291 321.0
HFD2_k127_6901002_3 denitrification pathway - GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0019645,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000008698 252.0
HFD2_k127_6901002_4 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000001161 225.0
HFD2_k127_6901002_6 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000000000000000000004509 153.0
HFD2_k127_6901002_7 4Fe-4S single cluster domain of Ferredoxin I - - - 0.00000000001892 67.0
HFD2_k127_6901002_8 ABC transporter - - - 0.0004055 49.0
HFD2_k127_6945760_0 Peptidase family M49 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 579.0
HFD2_k127_6945760_1 HI0933 family K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 418.0
HFD2_k127_6945760_10 Putative RNA methylase family UPF0020 - - - 0.00001225 51.0
HFD2_k127_6945760_2 valine-tRNA ligase activity K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 394.0
HFD2_k127_6945760_3 Tfp pilus assembly protein tip-associated adhesin K02674,K14379 - 3.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008257 358.0
HFD2_k127_6945760_4 Domain of unknown function (DUF4153) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 324.0
HFD2_k127_6945760_5 Protein of unknown function, DUF480 K09915 - - 0.0000000000000000000000000000000000000000000000000000000005074 209.0
HFD2_k127_6945760_6 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000006676 196.0
HFD2_k127_6945760_7 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000002026 169.0
HFD2_k127_6945760_8 cellulose binding - - - 0.000000000000002511 80.0
HFD2_k127_6945760_9 ubiE/COQ5 methyltransferase family - - - 0.0000002746 53.0
HFD2_k127_6954011_0 cAMP biosynthetic process K18672 GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 311.0
HFD2_k127_6954011_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 301.0
HFD2_k127_6954011_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009824 280.0
HFD2_k127_6954011_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0030091,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000006542 228.0
HFD2_k127_6954011_4 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000002763 153.0
HFD2_k127_6972901_0 methionyl-tRNA aminoacylation K01874,K01890,K06878 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20 9.332e-268 843.0
HFD2_k127_6972901_1 membrane organization K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007897 291.0
HFD2_k127_6972901_2 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000001329 200.0
HFD2_k127_6972901_3 heme binding K21471 - - 0.00000000000000000000000000000000000000000000000001328 189.0
HFD2_k127_6972901_4 Psort location Cytoplasmic, score 8.96 - - - 0.00000000000000000000000000000002085 126.0
HFD2_k127_6972901_5 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.00000000000000000009842 102.0
HFD2_k127_6972901_6 Glycosyl transferase - - - 0.000000000000443 79.0
HFD2_k127_6972901_7 Spermine/spermidine synthase domain - - - 0.000000002002 68.0
HFD2_k127_6983219_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00167,K11381,K21417 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 418.0
HFD2_k127_6983219_1 e3 binding domain K00658,K09699 - 2.3.1.168,2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 367.0
HFD2_k127_6983219_2 Dehydrogenase E1 component K00161,K00166,K11381,K21416 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 310.0
HFD2_k127_6983219_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K11381 - 1.2.4.4 0.0000000000000000000001569 98.0
HFD2_k127_7016647_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 1.351e-232 732.0
HFD2_k127_7016647_1 Major Facilitator Superfamily K02445 - - 6.122e-198 625.0
HFD2_k127_7016647_2 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 451.0
HFD2_k127_7016647_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008366 286.0
HFD2_k127_7016647_4 Fumarylacetoacetate (FAA) hydrolase family K16165 - 3.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000001139 239.0
HFD2_k127_7016647_5 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000001238 228.0
HFD2_k127_7016647_6 - - - - 0.00000000000000000000000000000000000000000000000000161 196.0
HFD2_k127_7016647_7 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000003373 203.0
HFD2_k127_7016647_8 Protein of unknown function (DUF971) K03593 - - 0.000000000000000000000000000006006 123.0
HFD2_k127_7025553_0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.0000000000000000000000000000000000000000000000000000000000000005419 244.0
HFD2_k127_7025553_1 Domain of unknown function (DUF4835) - - - 0.00000000000000000000000000000000000000000000000000000000004713 216.0
HFD2_k127_7025553_2 photosystem II stabilization - - - 0.00000000000000000000000001306 119.0
HFD2_k127_7025553_3 Bacterial Ig-like domain - - - 0.000000000008972 78.0
HFD2_k127_7025553_4 photosystem II stabilization K02237 - - 0.00001248 53.0
HFD2_k127_7036835_0 membrane organization K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 573.0
HFD2_k127_7036835_1 tRNA-splicing ligase RtcB K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002099 256.0
HFD2_k127_7036835_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000007152 211.0
HFD2_k127_7036835_3 Archease protein family (MTH1598/TM1083) - - - 0.000000000000005584 83.0
HFD2_k127_7061733_0 PFAM peptidase M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 399.0
HFD2_k127_7061733_1 ATPase activity K01990,K13926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 332.0
HFD2_k127_7061733_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000239 252.0
HFD2_k127_7061733_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000002518 127.0
HFD2_k127_7084303_0 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 420.0
HFD2_k127_7084303_2 aminopeptidase N - - - 0.00000000000001277 88.0
HFD2_k127_7095030_0 Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000009551 238.0
HFD2_k127_7095030_1 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000002738 205.0
HFD2_k127_7095030_2 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000002829 130.0
HFD2_k127_7207815_0 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 1.411e-217 681.0
HFD2_k127_7207815_1 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 591.0
HFD2_k127_7207815_10 PAS fold K11354 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000009702 220.0
HFD2_k127_7207815_11 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000003109 201.0
HFD2_k127_7207815_12 ATP synthesis coupled electron transport K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000000001314 138.0
HFD2_k127_7207815_13 Belongs to the complex I subunit 6 family K00339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000002532 131.0
HFD2_k127_7207815_14 Protein of unknown function, DUF393 - - - 0.000000000000000000000000002199 123.0
HFD2_k127_7207815_15 Winged helix DNA-binding domain - - - 0.000000000000000000000004086 105.0
HFD2_k127_7207815_16 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins K03817 - - 0.00000000000000000004598 102.0
HFD2_k127_7207815_17 metallopeptidase activity K01179,K01181 - 3.2.1.4,3.2.1.8 0.000000000000000005442 100.0
HFD2_k127_7207815_18 - - - - 0.00000000000000001329 87.0
HFD2_k127_7207815_19 Histidine kinase - - - 0.00000000000000001714 92.0
HFD2_k127_7207815_2 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006932 580.0
HFD2_k127_7207815_3 aldo keto reductase K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 522.0
HFD2_k127_7207815_4 Putative citrate transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 454.0
HFD2_k127_7207815_5 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 400.0
HFD2_k127_7207815_6 pfam abc K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 306.0
HFD2_k127_7207815_7 transmembrane transport K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 304.0
HFD2_k127_7207815_8 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002014 259.0
HFD2_k127_7207815_9 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001271 247.0
HFD2_k127_7304847_0 Belongs to the PstS family K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 441.0
HFD2_k127_7304847_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 402.0
HFD2_k127_7304847_10 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000000000000000003785 173.0
HFD2_k127_7304847_11 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000002401 131.0
HFD2_k127_7304847_12 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000004419 91.0
HFD2_k127_7304847_2 Phosphate transport system permease protein PstA K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 379.0
HFD2_k127_7304847_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006828 353.0
HFD2_k127_7304847_4 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 318.0
HFD2_k127_7304847_5 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 310.0
HFD2_k127_7304847_6 racemase activity, acting on amino acids and derivatives K01779 - 5.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000001018 264.0
HFD2_k127_7304847_7 protein histidine kinase activity K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000036 271.0
HFD2_k127_7304847_8 phosphorelay signal transduction system K07658 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003346 248.0
HFD2_k127_7304847_9 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000005298 200.0
HFD2_k127_7373904_0 aminopeptidase activity K01301 - 3.4.17.21 1.577e-286 899.0
HFD2_k127_7373904_1 Carbon starvation protein K06200 - - 1.973e-233 737.0
HFD2_k127_7373904_10 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001688 283.0
HFD2_k127_7373904_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002754 284.0
HFD2_k127_7373904_12 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000001371 252.0
HFD2_k127_7373904_13 Phenylacetic acid catabolic protein K02609 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000001099 243.0
HFD2_k127_7373904_14 peptide catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000005618 255.0
HFD2_k127_7373904_15 phosphatidate cytidylyltransferase activity K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000006186 236.0
HFD2_k127_7373904_16 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000004982 223.0
HFD2_k127_7373904_17 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000006178 207.0
HFD2_k127_7373904_18 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000002215 186.0
HFD2_k127_7373904_19 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000003782 152.0
HFD2_k127_7373904_2 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 580.0
HFD2_k127_7373904_20 - - - - 0.00000000000000000000000000000002714 134.0
HFD2_k127_7373904_21 Protein of unknown function (DUF1573) - - - 0.000000000000000000001497 104.0
HFD2_k127_7373904_22 ABC transporter K06147 - - 0.0000000003799 61.0
HFD2_k127_7373904_23 Protein of unknown function (DUF1573) - - - 0.0000005434 60.0
HFD2_k127_7373904_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K14441 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 521.0
HFD2_k127_7373904_4 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009482 517.0
HFD2_k127_7373904_5 Belongs to the thiolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 509.0
HFD2_k127_7373904_6 translation initiation factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 325.0
HFD2_k127_7373904_7 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 316.0
HFD2_k127_7373904_8 membrane organization K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 323.0
HFD2_k127_7373904_9 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074,K01782 - 1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 294.0
HFD2_k127_739775_0 TonB-dependent receptor - - - 0.0 1042.0
HFD2_k127_739775_1 - - - - 5.173e-269 849.0
HFD2_k127_739775_10 COG3209 Rhs family protein - - - 0.0000000000000000000000000006045 133.0
HFD2_k127_739775_11 cellulase activity K01201 - 3.2.1.45 0.00000000000000002369 99.0
HFD2_k127_739775_12 protein secretion K01179 - 3.2.1.4 0.000000000002114 82.0
HFD2_k127_739775_13 pathogenesis - - - 0.000000000149 76.0
HFD2_k127_739775_14 Protein conserved in bacteria - - - 0.0000003817 64.0
HFD2_k127_739775_2 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 427.0
HFD2_k127_739775_3 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 432.0
HFD2_k127_739775_4 Glycosyl Hydrolase Family 88 K15532 - 3.2.1.172 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 419.0
HFD2_k127_739775_5 purine nucleotide biosynthetic process K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 351.0
HFD2_k127_739775_6 pectinesterase activity K10117 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 359.0
HFD2_k127_739775_7 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009585 338.0
HFD2_k127_739775_8 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 334.0
HFD2_k127_739775_9 protein secretion K01179 - 3.2.1.4 0.000000000000000000000000000000005541 151.0
HFD2_k127_7410980_0 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 3.93e-229 739.0
HFD2_k127_7410980_1 Alpha amylase, catalytic domain K00705,K01176,K01187,K01208,K05341,K21575 - 2.4.1.25,2.4.1.4,3.2.1.1,3.2.1.133,3.2.1.135,3.2.1.20,3.2.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 572.0
HFD2_k127_7410980_2 ATPase activity K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 447.0
HFD2_k127_7410980_3 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000009648 224.0
HFD2_k127_7410980_4 synthase K00705,K01176,K01187,K01208,K05341,K21575 - 2.4.1.25,2.4.1.4,3.2.1.1,3.2.1.133,3.2.1.135,3.2.1.20,3.2.1.54 0.00000000000000000000000000005581 119.0
HFD2_k127_7413699_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0 1008.0
HFD2_k127_7413699_1 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 344.0
HFD2_k127_7413699_2 oligopeptide transport K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006562 346.0
HFD2_k127_7413699_3 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 326.0
HFD2_k127_7413699_4 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K01760 - 2.5.1.48,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005536 308.0
HFD2_k127_7413699_5 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003803 248.0
HFD2_k127_7413699_7 DinB superfamily - - - 0.00000002207 66.0
HFD2_k127_7413699_8 Anti-sigma-K factor rskA - - - 0.000001828 51.0
HFD2_k127_7413699_9 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.00002795 50.0
HFD2_k127_7428999_0 C-terminus of AA_permease K03294 - - 4.021e-234 732.0
HFD2_k127_7428999_1 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008447 339.0
HFD2_k127_7428999_2 queuosine metabolic process K04068,K10026 - 1.97.1.4,4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 293.0
HFD2_k127_7428999_3 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000001122 137.0
HFD2_k127_7428999_4 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000002261 89.0
HFD2_k127_7510392_0 nucleotide-excision repair K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 576.0
HFD2_k127_7510392_1 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 564.0
HFD2_k127_7510392_10 - - - - 0.00002338 55.0
HFD2_k127_7510392_2 SMART PUA domain containing protein K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 367.0
HFD2_k127_7510392_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000762 282.0
HFD2_k127_7510392_4 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000004123 220.0
HFD2_k127_7510392_5 glycolate biosynthetic process K01091,K06019 - 3.1.3.18,3.6.1.1 0.000000000000000000000000000000000000000000000000000000000002146 216.0
HFD2_k127_7510392_6 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000002275 206.0
HFD2_k127_7510392_7 - K07275 - - 0.000000000000000000000000000000000000000000000004202 182.0
HFD2_k127_7510392_8 - - - - 0.00000000000000000000000000000000000003381 145.0
HFD2_k127_7510392_9 Glyoxalase-like domain - - - 0.000000000000000000000000000000003357 132.0
HFD2_k127_751352_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 552.0
HFD2_k127_751352_1 queuine tRNA-ribosyltransferase activity K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 490.0
HFD2_k127_751352_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006782 316.0
HFD2_k127_751352_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus K03624 - - 0.0000000000000000000000000000000000000000000000000000002063 198.0
HFD2_k127_751352_4 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.0000000000000000000000000004455 116.0
HFD2_k127_751352_5 - - - - 0.000000005347 66.0
HFD2_k127_7517663_0 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 417.0
HFD2_k127_7517663_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000001097 232.0
HFD2_k127_7517663_2 DoxX K15977 - - 0.00000000000000000000000000000000000000005542 158.0
HFD2_k127_7517663_3 - - - - 0.00000000000000000000005122 98.0
HFD2_k127_7517663_4 Cell wall-associated hydrolase - - - 0.000000006912 59.0
HFD2_k127_7540824_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 528.0
HFD2_k127_7540824_1 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 426.0
HFD2_k127_7540824_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 298.0
HFD2_k127_7540824_3 ergosterol biosynthetic process K02291,K21679 - 2.5.1.32,2.5.1.99,4.2.3.156 0.0000000000000000000000000000000000000000000000000000000000000000000000001116 259.0
HFD2_k127_7540824_4 ergosterol biosynthetic process K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000002831 259.0
HFD2_k127_7540824_5 Flavin containing amine oxidoreductase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000002224 244.0
HFD2_k127_7540824_6 Hep Hag repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002386 254.0
HFD2_k127_7540824_7 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000005637 132.0
HFD2_k127_7540824_8 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.000000000000000000000005495 108.0
HFD2_k127_7540824_9 cell wall surface anchor family protein - - - 0.0000001266 66.0
HFD2_k127_7579699_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 494.0
HFD2_k127_7579699_1 TIGRFAM Aspartate kinase K12524 - 1.1.1.3,2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 446.0
HFD2_k127_7579699_2 proton-transporting ATP synthase activity, rotational mechanism K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007702 320.0
HFD2_k127_7579699_3 Sulfatase-modifying factor enzyme 1 K01176,K01206,K01218,K01219,K01224 - 3.2.1.1,3.2.1.51,3.2.1.78,3.2.1.81,3.2.1.89 0.00000000000000000000000000000000000000008875 176.0
HFD2_k127_7579699_4 cellulose binding - - - 0.0000000000000000006246 104.0
HFD2_k127_7697028_0 siderophore transport K02014 - - 1.132e-226 721.0
HFD2_k127_7697028_1 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000368 237.0
HFD2_k127_7697028_2 - - - - 0.00001076 58.0
HFD2_k127_7711493_0 pfkB family carbohydrate kinase - - - 2.788e-194 610.0
HFD2_k127_7711493_1 Belongs to the glycosyl hydrolase 28 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 559.0
HFD2_k127_7711493_10 belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000000000000000000000000000007046 149.0
HFD2_k127_7711493_11 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000006682 142.0
HFD2_k127_7711493_12 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000001339 95.0
HFD2_k127_7711493_13 metallocarboxypeptidase activity - - - 0.000000000000000005052 98.0
HFD2_k127_7711493_14 COG1196 Chromosome segregation ATPases - - - 0.00000000000009995 81.0
HFD2_k127_7711493_15 Regulatory protein, FmdB family - - - 0.0000000007156 62.0
HFD2_k127_7711493_16 Domain of unknown function (DUF4349) - - - 0.000000000723 69.0
HFD2_k127_7711493_18 Protein of unknown function (DUF2892) - - - 0.000000005532 59.0
HFD2_k127_7711493_19 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000007287 60.0
HFD2_k127_7711493_2 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 407.0
HFD2_k127_7711493_3 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 364.0
HFD2_k127_7711493_4 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 298.0
HFD2_k127_7711493_5 PFAM glycoside hydrolase family 28 K19172 - - 0.00000000000000000000000000000000000000000000000000000000000000000003325 254.0
HFD2_k127_7711493_6 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000000000002022 230.0
HFD2_k127_7711493_7 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000001298 182.0
HFD2_k127_7711493_8 OsmC-like protein K07397 - - 0.00000000000000000000000000000000000001468 149.0
HFD2_k127_7711493_9 NHL repeat containing protein - - - 0.00000000000000000000000000000000000001793 162.0
HFD2_k127_773454_0 Amidohydrolase family - - - 0.0 1220.0
HFD2_k127_773454_1 lipoprotein localization to outer membrane K09808,K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 299.0
HFD2_k127_773454_2 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000354 241.0
HFD2_k127_773454_3 lipoprotein localization to outer membrane K09808 - - 0.000000000000000000000000000000000000000000000000000000006241 210.0
HFD2_k127_773454_4 enterobactin catabolic process K07017 - - 0.000000000000000000000000000000000000000000003828 173.0
HFD2_k127_773454_5 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.000000000000000000003634 97.0
HFD2_k127_773454_6 phosphorelay signal transduction system - - - 0.0000000000000000000309 94.0
HFD2_k127_7782587_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 297.0
HFD2_k127_7782587_1 PFAM Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000002383 245.0
HFD2_k127_7782587_2 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.00000000000000000000000000000000000000000000000001245 199.0
HFD2_k127_7782587_3 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.0000000000000000000000000000000000000000000000002273 189.0
HFD2_k127_7782587_4 - - - - 0.000000000000000000000000000000000000001057 158.0
HFD2_k127_7782587_5 - - - - 0.0000000000000000000000001314 114.0
HFD2_k127_7789366_0 PFAM glycoside hydrolase family 3 domain protein K05349 - 3.2.1.21 8.123e-255 809.0
HFD2_k127_7789366_1 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 337.0
HFD2_k127_7789366_2 carbohydrate transport K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 318.0
HFD2_k127_7792471_0 Uroporphyrinogen decarboxylase (URO-D) K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006780,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046394,GO:0046483,GO:0046501,GO:0046502,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 403.0
HFD2_k127_7792471_1 glutamyl-tRNA reductase activity K02407,K02492 GO:0005575,GO:0005623,GO:0009288,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 390.0
HFD2_k127_7792471_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 325.0
HFD2_k127_7792471_3 cytochrome complex assembly - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005656 264.0
HFD2_k127_7792471_4 uroporphyrinogen-III synthase activity K01719,K02302,K02303,K13542 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000000000000000000000000000000000000000002497 179.0
HFD2_k127_7827437_0 - - - - 1.521e-292 947.0
HFD2_k127_7827437_1 Involved in the tonB-independent uptake of proteins K07277 - - 2.69e-262 833.0
HFD2_k127_7827437_2 lipopolysaccharide-transporting ATPase activity K07091,K11720 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 387.0
HFD2_k127_7827437_3 lipopolysaccharide-transporting ATPase activity K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 378.0
HFD2_k127_7827437_4 - - - - 0.000000000000000000000000000000000000002138 159.0
HFD2_k127_7853242_0 ribonuclease E activity K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 576.0
HFD2_k127_7853242_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 436.0
HFD2_k127_7853242_10 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000000000000007634 107.0
HFD2_k127_7853242_11 Putative regulatory protein - - - 0.0000000000000000003502 95.0
HFD2_k127_7853242_12 Tetratricopeptide repeat - - - 0.00000000000000001481 96.0
HFD2_k127_7853242_13 TIGRFAM competence protein ComEA K02237 - - 0.00000000001414 71.0
HFD2_k127_7853242_14 ftsk spoiiie K03466 - - 0.00000000003638 74.0
HFD2_k127_7853242_2 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 436.0
HFD2_k127_7853242_3 aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 406.0
HFD2_k127_7853242_4 Bacteriophage N4 adsorption protein B K11740 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 342.0
HFD2_k127_7853242_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 316.0
HFD2_k127_7853242_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009877 265.0
HFD2_k127_7853242_7 2-phosphosulfolactate phosphatase activity K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.000000000000000000000000000000000000000000000000000000000006897 215.0
HFD2_k127_7853242_8 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000000000000005379 201.0
HFD2_k127_7853242_9 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000000008812 154.0
HFD2_k127_7987948_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01848 - 5.4.99.2 9.253e-269 835.0
HFD2_k127_7987948_1 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007104 575.0
HFD2_k127_7987948_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 433.0
HFD2_k127_7987948_3 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 467.0
HFD2_k127_7987948_4 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007964 307.0
HFD2_k127_7987948_5 PFAM Endonuclease Exonuclease phosphatase K07004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001294 317.0
HFD2_k127_7987948_6 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000002211 179.0
HFD2_k127_7987948_7 cell adhesion involved in biofilm formation K20276 - - 0.000000000000000000000000000005985 140.0
HFD2_k127_7987948_8 Putative Ig domain - - - 0.00000000000000004692 98.0
HFD2_k127_7987948_9 CHRD domain - - - 0.00000000006855 69.0
HFD2_k127_7991881_0 Belongs to the peptidase S8 family - - - 0.0 1160.0
HFD2_k127_7991881_1 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 2.708e-247 794.0
HFD2_k127_7991881_2 PFAM Uncharacterised protein family (UPF0164) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 297.0
HFD2_k127_7991881_3 extracellular matrix structural constituent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002645 267.0
HFD2_k127_7991881_4 peptidyl-prolyl cis-trans isomerase activity K03769,K03771,K07533 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000008529 235.0
HFD2_k127_7993443_0 formate dehydrogenase (NAD+) activity K00336 - 1.6.5.3 4.386e-213 678.0
HFD2_k127_7993443_1 Aminotransferase class I and II K14260 - 2.6.1.2,2.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 520.0
HFD2_k127_7993443_2 Peptidase, M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 473.0
HFD2_k127_7993443_3 quinone binding K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 411.0
HFD2_k127_7993443_4 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 379.0
HFD2_k127_7993443_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K02573 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000477 241.0
HFD2_k127_7993443_6 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000007272 229.0
HFD2_k127_8068699_0 Glycosyl transferase family, helical bundle domain K00756,K00758 - 2.4.2.2,2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 465.0
HFD2_k127_8068699_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 319.0
HFD2_k127_8068699_2 Inositol monophosphatase K01082,K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008393 284.0
HFD2_k127_8068699_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000002547 230.0
HFD2_k127_8068699_4 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000004656 118.0
HFD2_k127_8068699_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000001906 111.0
HFD2_k127_8068699_6 Ferredoxin - - - 0.000000000000001526 83.0
HFD2_k127_8068699_7 Response regulator receiver - - - 0.00000000000006245 77.0
HFD2_k127_8068699_8 ADP-ribose pyrophosphatase K01515 - 3.6.1.13 0.00005403 47.0
HFD2_k127_8079090_0 Putative modulator of DNA gyrase K03568 - - 2.501e-199 635.0
HFD2_k127_8079090_1 phosphorelay signal transduction system K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 552.0
HFD2_k127_8079090_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 419.0
HFD2_k127_8079090_3 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000001473 213.0
HFD2_k127_8079090_4 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000005476 206.0
HFD2_k127_8079090_5 Peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000006536 202.0
HFD2_k127_8079090_6 FtsZ-dependent cytokinesis - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000001878 174.0
HFD2_k127_8079090_7 phosphatidate phosphatase activity K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.000000000000000000000000000000000000000000764 171.0
HFD2_k127_8079090_8 Universal stress protein - - - 0.00000000000000000000000001871 115.0
HFD2_k127_8079090_9 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000002349 91.0
HFD2_k127_8121836_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 1.753e-308 960.0
HFD2_k127_8121836_1 Fumarase C C-terminus K01679,K01744 - 4.2.1.2,4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006572 479.0
HFD2_k127_8121836_10 TIGRFAM TonB family protein K03832 - - 0.000000000000000003871 93.0
HFD2_k127_8121836_11 peptidyl-tyrosine sulfation - - - 0.00000000000000002296 96.0
HFD2_k127_8121836_12 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000002267 82.0
HFD2_k127_8121836_13 antisigma factor binding - - - 0.0005415 48.0
HFD2_k127_8121836_2 Catalyzes the sodium-dependent transport of glutamate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 370.0
HFD2_k127_8121836_3 Sigma-54 interaction domain K11384 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 339.0
HFD2_k127_8121836_4 MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000002355 244.0
HFD2_k127_8121836_5 Aminoacyl-tRNA editing domain K03976 - - 0.00000000000000000000000000000000000000000000000000002214 199.0
HFD2_k127_8121836_6 ABC-type phosphate transport system periplasmic K02040 - - 0.000000000000000000000000000000000000002505 158.0
HFD2_k127_8121836_7 PFAM Biopolymer transport protein ExbD TolR - - - 0.00000000000000000000000000000000000002589 149.0
HFD2_k127_8121836_8 Outer membrane transport energization protein ExbD - - - 0.0000000000000000000000000000000000001427 148.0
HFD2_k127_8121836_9 PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.0000000000000000000000004829 116.0
HFD2_k127_8126614_0 cellulose binding - - - 1.655e-261 818.0
HFD2_k127_8126614_1 - - - - 0.0001641 52.0
HFD2_k127_822761_0 FeS assembly protein SufB K09014 - - 1e-253 791.0
HFD2_k127_822761_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006417 575.0
HFD2_k127_822761_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 484.0
HFD2_k127_822761_3 ATPase activity K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 395.0
HFD2_k127_822761_4 iron-sulfur cluster assembly K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007766 396.0
HFD2_k127_822761_5 transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000000003147 118.0
HFD2_k127_822761_7 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000309 55.0
HFD2_k127_8233495_0 (ABC) transporter K06147,K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 511.0
HFD2_k127_8233495_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 452.0
HFD2_k127_8233495_10 YbbR-like protein - - - 0.00003504 55.0
HFD2_k127_8233495_2 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 334.0
HFD2_k127_8233495_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 351.0
HFD2_k127_8233495_4 electron transfer activity K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002692 284.0
HFD2_k127_8233495_5 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000004702 270.0
HFD2_k127_8233495_6 PFAM Uncharacterised ACR, COG1259 K03617,K03702,K08999 GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0030312,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000008968 217.0
HFD2_k127_8233495_7 ethanolamine catabolic process K04027 - - 0.000000000000000000000000000000000000000003904 157.0
HFD2_k127_8233495_8 ethanolamine catabolic process - - - 0.00000000000000000000000000000000003516 142.0
HFD2_k127_8233495_9 AsmA family K07289 - - 0.000000000007587 74.0
HFD2_k127_823547_0 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 4.248e-212 662.0
HFD2_k127_823547_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 610.0
HFD2_k127_823547_10 JAB1/Mov34/MPN/PAD-1 ubiquitin protease - - - 0.0000000000000000000000552 104.0
HFD2_k127_823547_11 PFAM thiamineS protein K03636 - - 0.00000000002874 68.0
HFD2_k127_823547_2 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 568.0
HFD2_k127_823547_3 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 524.0
HFD2_k127_823547_4 Fumarylacetoacetate (FAA) hydrolase family K18336 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 415.0
HFD2_k127_823547_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 375.0
HFD2_k127_823547_6 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002894 246.0
HFD2_k127_823547_7 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002866 243.0
HFD2_k127_823547_9 Protein of unknown function (DUF1207) - - - 0.000000000000000000000000000003496 130.0
HFD2_k127_8238440_0 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 335.0
HFD2_k127_8238440_1 4-amino-4-deoxy-L-arabinose transferase activity K13687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 344.0
HFD2_k127_8238440_2 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001354 263.0
HFD2_k127_8238440_3 EthD domain - - - 0.0000000000000000000000000000001436 126.0
HFD2_k127_8248116_0 phosphorelay signal transduction system K03413,K13589 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 384.0
HFD2_k127_8248116_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000006252 221.0
HFD2_k127_8248116_3 peptidoglycan binding K03749,K07114,K08300,K09859 - 3.1.26.12 0.0000000000000000000000003175 118.0
HFD2_k127_8304515_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 407.0
HFD2_k127_8304515_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003313 279.0
HFD2_k127_8312619_0 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 415.0
HFD2_k127_8312619_1 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005208 271.0
HFD2_k127_8312619_2 Two component transcriptional regulator, winged helix family K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008054 255.0
HFD2_k127_8312619_3 PhoQ Sensor K07636 - 2.7.13.3 0.000000000000000000000000000000000000000001676 162.0
HFD2_k127_8312619_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000001955 81.0
HFD2_k127_8382005_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 305.0
HFD2_k127_8382005_1 translation initiation factor activity K03699 - - 0.00000000000000000000000000000000000000000000000001108 186.0
HFD2_k127_8382005_2 TIGRFAM SUF system FeS K04488 - - 0.000000000000000000000000000000000000000000000003165 175.0
HFD2_k127_8382005_3 protein maturation K13628 - - 0.000000000000000000000000000000000000001444 150.0
HFD2_k127_8382005_4 FeS assembly SUF system protein - - - 0.000000000000000000000000000000001766 133.0
HFD2_k127_8411076_0 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000005797 223.0
HFD2_k127_8411076_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K00556,K03218,K03437 - 2.1.1.185,2.1.1.34 0.00000000000000000000000000000000000000000000000000000001273 205.0
HFD2_k127_8411076_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000001304 201.0
HFD2_k127_8411076_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000003207 150.0
HFD2_k127_846819_0 ATPase activity K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 367.0
HFD2_k127_846819_1 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007311 346.0
HFD2_k127_846819_2 transport, permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 324.0
HFD2_k127_846819_3 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000000000000001115 165.0
HFD2_k127_846819_4 self proteolysis K04771 - 3.4.21.107 0.0000000000000000005776 103.0
HFD2_k127_846819_5 Belongs to the peptidase S8 family - - - 0.000000000002216 81.0
HFD2_k127_8475787_0 N-Acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 344.0
HFD2_k127_8475787_1 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000002532 189.0
HFD2_k127_8475787_2 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.000000000000000000000000000000006512 132.0
HFD2_k127_8475787_3 histidine kinase HAMP region domain protein K03406 - - 0.00001215 56.0
HFD2_k127_8493455_0 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 372.0
HFD2_k127_8493455_1 Elongation factor Tu domain 2 K06207 - - 0.00000000000000000000000000000000000000000000000000000762 192.0
HFD2_k127_8493455_2 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000874 156.0
HFD2_k127_850958_0 thiosulfate sulfurtransferase activity K01011 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 412.0
HFD2_k127_850958_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003743 276.0
HFD2_k127_850958_2 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002509 236.0
HFD2_k127_850958_4 Enoyl-(Acyl carrier protein) reductase - - - 0.000007971 50.0
HFD2_k127_850958_5 peptidyl-tyrosine sulfation - - - 0.0008754 49.0
HFD2_k127_8541454_0 ATP-dependent peptidase activity K01338 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004175,GO:0004176,GO:0004252,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009408,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0017171,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051603,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 312.0
HFD2_k127_8541454_1 Zinc carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002061 288.0
HFD2_k127_8541454_2 Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA K00556,K03218,K03437,K15333 GO:0001510,GO:0002128,GO:0002938,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008175,GO:0008757,GO:0009020,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0106050,GO:0140098,GO:0140101,GO:1901360 2.1.1.185,2.1.1.34 0.0000000000000000000000000000000000000000000000000000000000027 220.0
HFD2_k127_8541454_3 spore germination - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000002406 171.0
HFD2_k127_8541454_5 Alpha beta - - - 0.0000000000000001023 90.0
HFD2_k127_8541454_6 converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.0000002997 55.0
HFD2_k127_8541454_7 Catalyzes the dehydration of D-mannonate K01686 - 4.2.1.8 0.0000004119 54.0
HFD2_k127_8541454_8 Yip1 domain - - - 0.0000005788 60.0
HFD2_k127_8541454_9 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00002569 47.0
HFD2_k127_8556142_0 DNA-directed 5'-3' RNA polymerase activity K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1110.0
HFD2_k127_8567258_0 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 546.0
HFD2_k127_8567258_1 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 502.0
HFD2_k127_8567258_10 cellulose binding - - - 0.0000000000000000000002129 111.0
HFD2_k127_8567258_11 phosphorelay signal transduction system - - - 0.000000000000000000003039 98.0
HFD2_k127_8567258_12 cellulose binding - - - 0.0000000000000001718 93.0
HFD2_k127_8567258_13 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000003561 76.0
HFD2_k127_8567258_2 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 419.0
HFD2_k127_8567258_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 403.0
HFD2_k127_8567258_4 ATP-dependent DNA helicase activity K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 395.0
HFD2_k127_8567258_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 329.0
HFD2_k127_8567258_6 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 312.0
HFD2_k127_8567258_7 Belongs to the RtcB family K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009104 287.0
HFD2_k127_8567258_8 Membrane - - - 0.0000000000000000000000000000000000000000002684 173.0
HFD2_k127_8567258_9 Calx-beta domain - - - 0.00000000000000000000000000000000001809 154.0
HFD2_k127_8603078_0 GTP-binding protein TypA K06207 - - 1.099e-230 730.0
HFD2_k127_8603078_1 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 611.0
HFD2_k127_8603078_10 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000008188 210.0
HFD2_k127_8603078_11 PFAM regulatory protein MarR K15973 - - 0.00000000000000000000000000000000000000000000008218 180.0
HFD2_k127_8603078_12 Belongs to the UPF0403 family - - - 0.000000000000000000000000000000000000000000001115 168.0
HFD2_k127_8603078_13 YceI-like domain - - - 0.0000000000000000000000000000000000000000002464 165.0
HFD2_k127_8603078_14 membrane-bound metal-dependent K07038 - - 0.0000000000000000000000000000000006904 143.0
HFD2_k127_8603078_15 - - - - 0.00000000000000000003302 98.0
HFD2_k127_8603078_16 COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family - - - 0.00000000001425 78.0
HFD2_k127_8603078_17 ATP-independent chaperone mediated protein folding - - - 0.0000000001683 68.0
HFD2_k127_8603078_2 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 452.0
HFD2_k127_8603078_3 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 382.0
HFD2_k127_8603078_4 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 334.0
HFD2_k127_8603078_5 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 319.0
HFD2_k127_8603078_6 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008489 274.0
HFD2_k127_8603078_7 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000003009 267.0
HFD2_k127_8603078_8 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009743 270.0
HFD2_k127_8603078_9 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000433 229.0
HFD2_k127_8613675_0 GTP binding K03977 GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 502.0
HFD2_k127_8613675_1 cheY-homologous receiver domain K02485 - - 0.000000000000000000000000001046 121.0
HFD2_k127_8613675_2 pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000002126 70.0
HFD2_k127_8649315_0 Belongs to the CarB family K01955 - 6.3.5.5 9.884e-228 721.0
HFD2_k127_8649315_1 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01955 - 6.3.5.5 5.272e-226 709.0
HFD2_k127_8649315_10 Haem-binding domain - - - 0.0000000000000000000000000000000000000000004066 169.0
HFD2_k127_8649315_11 Domain of unknown function (DUF1905) - - - 0.00000000000000000000000000000000000005745 155.0
HFD2_k127_8649315_12 protein secretion K20276 - - 0.000000000000000000000000001253 118.0
HFD2_k127_8649315_13 Outer membrane protein beta-barrel domain - - - 0.0000000000000000001289 96.0
HFD2_k127_8649315_14 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000001337 91.0
HFD2_k127_8649315_15 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K07291 - 2.7.8.34 0.000000000000001017 88.0
HFD2_k127_8649315_16 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000001146 85.0
HFD2_k127_8649315_17 - - - - 0.000000000000001801 88.0
HFD2_k127_8649315_18 Concanavalin A-like lectin/glucanases superfamily - - - 0.00000000001855 74.0
HFD2_k127_8649315_19 ATP-independent chaperone mediated protein folding - - - 0.000003391 56.0
HFD2_k127_8649315_2 nucleotide-excision repair K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 560.0
HFD2_k127_8649315_3 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 468.0
HFD2_k127_8649315_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 458.0
HFD2_k127_8649315_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 360.0
HFD2_k127_8649315_6 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 289.0
HFD2_k127_8649315_7 Acetyltransferase (GNAT) domain K22479 - - 0.000000000000000000000000000000000000000000000000000000000000000001089 232.0
HFD2_k127_8649315_8 translation initiation inhibitor, yjgF family K04782 - 4.2.99.21 0.00000000000000000000000000000000000000000000008073 175.0
HFD2_k127_8649315_9 Cupin domain - - - 0.000000000000000000000000000000000000000000003005 167.0
HFD2_k127_8671289_0 lysine biosynthetic process via aminoadipic acid - - - 1.228e-289 907.0
HFD2_k127_8671289_1 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 570.0
HFD2_k127_8671289_2 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 447.0
HFD2_k127_8671289_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008016 368.0
HFD2_k127_8671289_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001819 282.0
HFD2_k127_8671289_5 Phosphate acetyl/butaryl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000001195 235.0
HFD2_k127_8671289_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001816 239.0
HFD2_k127_8671289_7 COG3258 Cytochrome c K19713 - 1.8.2.2 0.0000000000000000000000000000000000000000000000003597 190.0
HFD2_k127_8671289_8 metallopeptidase activity K06974 - - 0.000000000000000000000000000002864 127.0
HFD2_k127_8671289_9 Transcriptional regulator - - - 0.00000000000000000000000000003229 123.0
HFD2_k127_8676440_0 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 1.416e-249 805.0
HFD2_k127_8676440_1 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.0000000000000000000000000000000000000000000000000000001024 200.0
HFD2_k127_8676440_2 N-acetylglucosamine kinase activity K00884 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363 2.7.1.59 0.0000000000000000000000000000000009062 138.0
HFD2_k127_8732995_0 TonB-dependent receptor - - - 9.341e-306 967.0
HFD2_k127_8732995_1 protein secretion K20276 - - 0.000000000000000000000000000000000000000000001676 175.0
HFD2_k127_8732995_2 FG-GAP repeat protein K01179,K01728,K03932 - 3.2.1.4,4.2.2.2 0.00000000000000000000000000000001723 132.0
HFD2_k127_877451_0 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 2.469e-229 731.0
HFD2_k127_877451_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 607.0
HFD2_k127_877451_2 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 351.0
HFD2_k127_877451_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 351.0
HFD2_k127_877451_4 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 309.0
HFD2_k127_877451_5 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006313 287.0
HFD2_k127_903999_0 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008447 282.0
HFD2_k127_903999_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03635,K03637 - 2.8.1.12,4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000007476 268.0
HFD2_k127_903999_10 Molybdopterin converting factor subunit K03635,K21142 - 2.8.1.12 0.000000000003076 72.0
HFD2_k127_903999_11 Pfam Adenylate and Guanylate cyclase catalytic domain K01768,K04755 - 4.6.1.1 0.00001351 55.0
HFD2_k127_903999_2 Oxidoreductase molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000007768 241.0
HFD2_k127_903999_3 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000002443 230.0
HFD2_k127_903999_4 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000001468 229.0
HFD2_k127_903999_5 Oxidoreductase molybdopterin binding - - - 0.000000000000000000000000000000000000000000000000000000006356 207.0
HFD2_k127_903999_6 Cytochrome b/b6/petB - - - 0.000000000000000000000000000000000000000000001627 171.0
HFD2_k127_903999_7 MoaE protein K21142 - 2.8.1.12 0.00000000000000000000000000000000000001076 150.0
HFD2_k127_903999_8 Phosphodiester glycosidase - - - 0.00000000000000000509 95.0
HFD2_k127_903999_9 - - - - 0.000000000000008453 78.0
HFD2_k127_938101_0 unfolded protein binding K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 1.949e-293 915.0
HFD2_k127_938101_1 response to heat K03694,K03695 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030312,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0040007,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000000000001277 198.0
HFD2_k127_938101_2 PFAM FecR protein K20276 - - 0.00000000000000000000000000000000000000000000000000003901 211.0
HFD2_k127_938101_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000002861 186.0
HFD2_k127_938101_4 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000001162 168.0
HFD2_k127_941095_0 Polysaccharide biosynthesis protein K02851 - 2.7.8.33,2.7.8.35 1.18e-207 660.0
HFD2_k127_941095_1 CTP:tRNA cytidylyltransferase activity K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009706 482.0
HFD2_k127_941095_2 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 377.0
HFD2_k127_941095_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008626 379.0
HFD2_k127_941095_4 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 364.0
HFD2_k127_941095_5 lipoprotein transporter activity K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 349.0
HFD2_k127_941095_6 efflux transmembrane transporter activity K12340 - - 0.0000000000000000000000000000000000000000000000000000000007809 219.0
HFD2_k127_941095_7 Putative heavy-metal-binding - - - 0.0000000000000000000000000000000000000000000009851 167.0
HFD2_k127_941095_8 metallocarboxypeptidase activity - - - 0.00000000000000004989 94.0
HFD2_k127_941095_9 amine dehydrogenase activity - - - 0.00000000000000005177 94.0
HFD2_k127_959482_0 protein targeting K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1290.0
HFD2_k127_959482_1 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000008578 187.0