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Overview

ID MAG01637
Name HFD2_bin.25
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Gemmatimonadota
Class Gemmatimonadetes
Order Gemmatimonadales
Family GWC2-71-9
Genus JAOTWJ01
Species
Assembly information
Completeness (%) 74.29
Contamination (%) 1.29
GC content (%) 72.0
N50 (bp) 15,243
Genome size (bp) 3,308,884

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2800

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_1001962_0 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000000000001588 149.0
HFD2_k127_1001962_1 membrane transporter protein K07090 - - 0.000000002488 62.0
HFD2_k127_1005121_0 Protein export membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 530.0
HFD2_k127_1025965_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 372.0
HFD2_k127_1025965_1 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 364.0
HFD2_k127_1025965_10 FHA domain K07315 - 3.1.3.3 0.00000004105 67.0
HFD2_k127_1025965_2 Protein kinase domain K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 339.0
HFD2_k127_1025965_3 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 304.0
HFD2_k127_1025965_4 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000001152 213.0
HFD2_k127_1025965_5 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.0000000000000000000000000000000000000002689 151.0
HFD2_k127_1025965_6 Forkhead associated domain - - - 0.0000000000000000000000000008544 124.0
HFD2_k127_1025965_8 Ami_3 K01448 - 3.5.1.28 0.00000000000005617 77.0
HFD2_k127_1025965_9 serine-type endopeptidase activity K04771 - 3.4.21.107 0.00000002363 68.0
HFD2_k127_1109069_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 3.56e-270 841.0
HFD2_k127_1109069_1 L-asparaginase K01424 - 3.5.1.1 4.531e-204 645.0
HFD2_k127_1109069_2 Dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 503.0
HFD2_k127_1109069_3 metal ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005893 494.0
HFD2_k127_1109069_4 GatB/GatE catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 441.0
HFD2_k127_1109069_5 Chalcone isomerase like - - - 0.00001178 51.0
HFD2_k127_1160956_0 Elongation factor G C-terminus K06207 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 569.0
HFD2_k127_1160956_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008703 413.0
HFD2_k127_1160956_2 Pyridoxal phosphate biosynthetic protein PdxA K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008636 317.0
HFD2_k127_1160956_3 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 297.0
HFD2_k127_1160956_4 Cation efflux family K16264 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000000000000000000000000000000000000000000000000000008968 258.0
HFD2_k127_1160956_5 PPIC-type PPIASE domain K03770 - 5.2.1.8 0.0000000000000000000000000000000001531 149.0
HFD2_k127_1210613_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1013.0
HFD2_k127_1210613_1 Insulinase (Peptidase family M16) K07263 - - 1.44e-271 870.0
HFD2_k127_1210613_10 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 428.0
HFD2_k127_1210613_11 antibiotic catabolic process K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 410.0
HFD2_k127_1210613_12 Belongs to the DapA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 417.0
HFD2_k127_1210613_13 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 403.0
HFD2_k127_1210613_14 HMGL-like K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 372.0
HFD2_k127_1210613_15 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 369.0
HFD2_k127_1210613_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 338.0
HFD2_k127_1210613_17 Glucose inhibited division protein A K21401 - 1.3.99.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 305.0
HFD2_k127_1210613_18 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000007304 253.0
HFD2_k127_1210613_19 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009287 251.0
HFD2_k127_1210613_2 Peptidase family M1 domain - - - 1.771e-260 818.0
HFD2_k127_1210613_20 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000001546 243.0
HFD2_k127_1210613_21 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000008666 250.0
HFD2_k127_1210613_22 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000001417 236.0
HFD2_k127_1210613_23 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003565 234.0
HFD2_k127_1210613_24 CcmB protein K02194 - - 0.00000000000000000000000000000000000000000000000000000000000003316 221.0
HFD2_k127_1210613_25 Prokaryotic glutathione synthetase, ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000009888 231.0
HFD2_k127_1210613_26 Belongs to the MIP aquaporin (TC 1.A.8) family K02440,K06188,K09874 - - 0.00000000000000000000000000000000000000000000000000000355 213.0
HFD2_k127_1210613_27 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000001906 193.0
HFD2_k127_1210613_28 Copper chaperone PCu(A)C K03619,K07152,K09796 GO:0003674,GO:0005048,GO:0005488,GO:0033218,GO:0042277 - 0.00000000000000000000000000000000000000000000000006052 185.0
HFD2_k127_1210613_29 cytochrome c oxidase K02351,K02862 - - 0.000000000000000000000000000000000000000000000004345 183.0
HFD2_k127_1210613_3 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 3.101e-203 663.0
HFD2_k127_1210613_30 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000001223 177.0
HFD2_k127_1210613_31 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000001964 177.0
HFD2_k127_1210613_32 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000002716 172.0
HFD2_k127_1210613_33 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000006366 150.0
HFD2_k127_1210613_34 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000000843 152.0
HFD2_k127_1210613_35 Methyltransferase domain - - - 0.000000000000000000000000000000000001238 153.0
HFD2_k127_1210613_36 Cold shock K03704 - - 0.0000000000000000000000000000000009934 131.0
HFD2_k127_1210613_37 PFAM Rhomboid family protein - - - 0.000000000000000000000000000003088 129.0
HFD2_k127_1210613_38 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000001502 119.0
HFD2_k127_1210613_39 Flavin reductase like domain - - - 0.0000000000000000000000000000929 123.0
HFD2_k127_1210613_4 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009753 604.0
HFD2_k127_1210613_40 Putative lumazine-binding - - - 0.000000000000000000000000002568 118.0
HFD2_k127_1210613_41 Late embryogenesis abundant protein - - - 0.0000000000000000000000001535 115.0
HFD2_k127_1210613_42 Domain of unknown function (DUF4342) - - - 0.0000000000000000000001113 100.0
HFD2_k127_1210613_43 CDP-alcohol phosphatidyltransferase K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000005468 95.0
HFD2_k127_1210613_44 OsmC-like protein K07397 - - 0.00000000000000004372 90.0
HFD2_k127_1210613_45 - - - - 0.000000000000000245 82.0
HFD2_k127_1210613_46 ATPase associated with various cellular activities AAA_5 K10912 - - 0.0000000000000135 79.0
HFD2_k127_1210613_47 Vitamin K epoxide reductase family - - - 0.0000000000001062 81.0
HFD2_k127_1210613_49 Transposase - - - 0.000000009645 66.0
HFD2_k127_1210613_5 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 611.0
HFD2_k127_1210613_50 Limonene-1,2-epoxide hydrolase catalytic domain K06893 - - 0.000003338 58.0
HFD2_k127_1210613_51 PFAM PKD domain containing protein - - - 0.00001268 57.0
HFD2_k127_1210613_52 OmpA family K03286 - - 0.00002211 56.0
HFD2_k127_1210613_6 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 559.0
HFD2_k127_1210613_7 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 571.0
HFD2_k127_1210613_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 542.0
HFD2_k127_1210613_9 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 533.0
HFD2_k127_125968_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.037e-265 837.0
HFD2_k127_125968_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 559.0
HFD2_k127_125968_10 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000001638 224.0
HFD2_k127_125968_11 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000003076 228.0
HFD2_k127_125968_12 Belongs to the TrpC family K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.00000000000000000000000000000000000000000000000000000005231 205.0
HFD2_k127_125968_13 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000001181 95.0
HFD2_k127_125968_14 Transcription factor zinc-finger K09981 - - 0.0000000000000004172 88.0
HFD2_k127_125968_2 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000856 520.0
HFD2_k127_125968_3 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007143 417.0
HFD2_k127_125968_4 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 392.0
HFD2_k127_125968_5 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 299.0
HFD2_k127_125968_6 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005013 273.0
HFD2_k127_125968_7 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003914 274.0
HFD2_k127_125968_8 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000003897 274.0
HFD2_k127_125968_9 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000003364 235.0
HFD2_k127_1295901_0 Belongs to the aldehyde dehydrogenase family K00130,K00135,K09472,K22187 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.1.8,1.2.1.99 3.7e-207 657.0
HFD2_k127_1295901_1 peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 469.0
HFD2_k127_1295901_10 Histidine kinase K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000005836 180.0
HFD2_k127_1295901_11 Cytochrome C and Quinol oxidase polypeptide I K15862 - 1.9.3.1 0.00000000000000000000000000000000000000203 151.0
HFD2_k127_1295901_12 Tetratricopeptide repeat - - - 0.000000000007934 77.0
HFD2_k127_1295901_13 PFAM SH3, type 3 - - - 0.000000003855 66.0
HFD2_k127_1295901_14 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000009663 61.0
HFD2_k127_1295901_2 Alcohol dehydrogenase GroES domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 435.0
HFD2_k127_1295901_3 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 359.0
HFD2_k127_1295901_4 ABC-type glycine betaine transport system K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 356.0
HFD2_k127_1295901_5 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 312.0
HFD2_k127_1295901_6 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 308.0
HFD2_k127_1295901_7 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 317.0
HFD2_k127_1295901_8 Cache domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000128 254.0
HFD2_k127_1295901_9 ATPases associated with a variety of cellular activities K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000006841 236.0
HFD2_k127_1422601_0 TonB dependent receptor K21573 - - 1.983e-283 902.0
HFD2_k127_1422601_1 hydrolase activity, hydrolyzing O-glycosyl compounds K01176,K01200 - 3.2.1.1,3.2.1.41 5.978e-227 719.0
HFD2_k127_1422601_10 Domain of unknown function (DUF4956) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004776 264.0
HFD2_k127_1422601_11 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000008425 270.0
HFD2_k127_1422601_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000007419 257.0
HFD2_k127_1422601_13 D-alanyl-D-alanine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000002435 244.0
HFD2_k127_1422601_14 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000007353 237.0
HFD2_k127_1422601_15 Zn_pept - - - 0.00000000000000000000000000000000000000000000000000000000000000008983 234.0
HFD2_k127_1422601_16 - - - - 0.000000000000000000000000000000000000000000000000002497 199.0
HFD2_k127_1422601_17 - - - - 0.0000000000000000000000000000000000343 136.0
HFD2_k127_1422601_18 Serine carboxypeptidase - - - 0.000000000000000000003354 109.0
HFD2_k127_1422601_19 ribonuclease activity - - - 0.000000000000000000005295 101.0
HFD2_k127_1422601_2 major facilitator K16211 - - 2.485e-203 646.0
HFD2_k127_1422601_20 - - - - 0.0000000005755 66.0
HFD2_k127_1422601_21 Pkd domain containing protein - - - 0.0000000009332 71.0
HFD2_k127_1422601_23 Uncharacterised nucleotidyltransferase - - - 0.00001328 57.0
HFD2_k127_1422601_24 Bacterial Ig-like domain 2 - - - 0.0003433 53.0
HFD2_k127_1422601_3 Alpha-amylase domain K01176 - 3.2.1.1 1.452e-200 638.0
HFD2_k127_1422601_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K21572 - - 6.253e-196 626.0
HFD2_k127_1422601_5 membrane K06373 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 577.0
HFD2_k127_1422601_6 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 565.0
HFD2_k127_1422601_7 Protein of unknown function (DUF445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 409.0
HFD2_k127_1422601_8 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 370.0
HFD2_k127_1422601_9 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007185 327.0
HFD2_k127_1441205_0 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 3.076e-215 686.0
HFD2_k127_1441205_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 595.0
HFD2_k127_1441205_10 Sugar (and other) transporter - - - 0.000000000000000009011 85.0
HFD2_k127_1441205_11 Putative regulatory protein - - - 0.00000000000000003305 87.0
HFD2_k127_1441205_2 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004381 401.0
HFD2_k127_1441205_3 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 372.0
HFD2_k127_1441205_4 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 383.0
HFD2_k127_1441205_5 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 366.0
HFD2_k127_1441205_6 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 306.0
HFD2_k127_1441205_7 riboflavin synthase, alpha K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.000000000000000000000000000000000000000000001172 184.0
HFD2_k127_1441205_8 6,7-dimethyl-8-ribityllumazine synthase activity K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000004686 136.0
HFD2_k127_1441205_9 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000002274 103.0
HFD2_k127_1443191_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 1.968e-211 711.0
HFD2_k127_1443191_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003464 267.0
HFD2_k127_1443191_2 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000007155 191.0
HFD2_k127_1443191_3 Outer membrane efflux protein K12340 - - 0.0000000000000000001601 104.0
HFD2_k127_1443191_4 - - - - 0.0000000000000000004181 101.0
HFD2_k127_1443191_5 - - - - 0.000000004373 68.0
HFD2_k127_1443191_6 NHL repeat - - - 0.00000003491 67.0
HFD2_k127_1443191_7 WD40 repeats - - - 0.00000009878 64.0
HFD2_k127_1445337_0 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007771 422.0
HFD2_k127_1445337_1 long-chain fatty acid transporting porin activity K07267 - - 0.00000000000000000000000000000000000000000000000000000000000000002115 242.0
HFD2_k127_1445337_2 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000003458 229.0
HFD2_k127_1445337_3 Histidine kinase HAMP - - - 0.00000000000000000000000000000000000000000000000000157 205.0
HFD2_k127_1445337_4 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000001322 116.0
HFD2_k127_1445337_5 phosphorelay signal transduction system K10941 - - 0.000000000000000000000107 104.0
HFD2_k127_1445337_6 Cytochrome c K07243 - - 0.0000000008047 68.0
HFD2_k127_1455113_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009969 324.0
HFD2_k127_1455113_1 Bacterial Ig-like domain 2 - - - 0.00004961 52.0
HFD2_k127_1469894_0 DHH family K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 507.0
HFD2_k127_1469894_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 482.0
HFD2_k127_1469894_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 312.0
HFD2_k127_1469894_3 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000000006921 194.0
HFD2_k127_1469894_4 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000005482 201.0
HFD2_k127_1469894_5 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.000000000000001038 87.0
HFD2_k127_1469894_6 Zinc ribbon domain protein K07164 - - 0.000000002199 67.0
HFD2_k127_1482055_0 Methylmalonyl-CoA mutase K01848,K11942 - 5.4.99.13,5.4.99.2 1.967e-254 794.0
HFD2_k127_1482055_1 Carboxyl transferase domain - - - 4.496e-243 768.0
HFD2_k127_1482055_10 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000002182 153.0
HFD2_k127_1482055_11 Transporter associated domain K03699 - - 0.0000000000000000000000000000000005686 145.0
HFD2_k127_1482055_12 Belongs to the enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.00000000000000000000002488 117.0
HFD2_k127_1482055_2 Acyclic terpene utilisation family protein AtuA - - - 2.886e-196 655.0
HFD2_k127_1482055_3 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009315 358.0
HFD2_k127_1482055_4 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 359.0
HFD2_k127_1482055_5 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002566 284.0
HFD2_k127_1482055_6 Belongs to the peptidase S8 family K01280 - 3.4.14.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003691 308.0
HFD2_k127_1482055_7 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000003917 216.0
HFD2_k127_1482055_8 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.00000000000000000000000000000000000000000000000000001367 207.0
HFD2_k127_1482055_9 - - - - 0.0000000000000000000000000000000000000000000561 164.0
HFD2_k127_1494770_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 603.0
HFD2_k127_1494770_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 514.0
HFD2_k127_1494770_2 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006075 472.0
HFD2_k127_1494770_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 370.0
HFD2_k127_1494770_4 PFAM Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 352.0
HFD2_k127_1494770_5 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003307 288.0
HFD2_k127_1494770_6 4Fe-4S dicluster domain K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004915 254.0
HFD2_k127_1494770_7 LVIVD repeat - - - 0.0000000000000000000000000000000000000002344 172.0
HFD2_k127_1494770_8 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000000000000003088 102.0
HFD2_k127_1494770_9 Protein of unknown function (DUF721) - - - 0.00000000000005093 75.0
HFD2_k127_1505761_0 Belongs to the glycosyl hydrolase 13 family K00700 - 2.4.1.18 1.617e-273 861.0
HFD2_k127_1505761_1 N-Acetylmuramoyl-L-alanine amidase K01187 - 3.2.1.20 4.461e-268 874.0
HFD2_k127_1505761_2 beta-galactosidase activity K01190 - 3.2.1.23 8.793e-245 771.0
HFD2_k127_1505761_3 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 537.0
HFD2_k127_1505761_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 479.0
HFD2_k127_1505761_5 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000001069 171.0
HFD2_k127_1529664_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005336 366.0
HFD2_k127_1529664_1 methyltransferase activity - - - 0.000000000000000000000000000000009083 132.0
HFD2_k127_1529664_2 KaiB - - - 0.000000000000000000000009213 109.0
HFD2_k127_1547791_0 cytochrome c oxidase subunit I K02274 - 1.9.3.1 6.803e-254 796.0
HFD2_k127_1547791_1 Secreted protein containing N-terminal Zinc-dependent carboxypeptidase related domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 618.0
HFD2_k127_1547791_10 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000494 121.0
HFD2_k127_1547791_11 Possibly the antitoxin component of a - - - 0.0002115 47.0
HFD2_k127_1547791_13 PIN domain K18828 - - 0.000607 47.0
HFD2_k127_1547791_2 Alpha/beta hydrolase family K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 399.0
HFD2_k127_1547791_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 380.0
HFD2_k127_1547791_4 PFAM Integrase catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001659 276.0
HFD2_k127_1547791_5 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008814 257.0
HFD2_k127_1547791_6 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000001103 231.0
HFD2_k127_1547791_7 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000001575 222.0
HFD2_k127_1547791_8 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000003978 212.0
HFD2_k127_1547791_9 DoxX - - - 0.0000000000000000000000000000002749 127.0
HFD2_k127_1597937_0 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 408.0
HFD2_k127_1597937_1 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000001528 261.0
HFD2_k127_1597937_2 Clp protease K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000002909 242.0
HFD2_k127_1597937_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000009629 188.0
HFD2_k127_1597937_4 SNARE associated Golgi protein - - - 0.0000000000000000000000000004455 128.0
HFD2_k127_1597937_5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000005645 97.0
HFD2_k127_1612686_0 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 445.0
HFD2_k127_1612686_1 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000003384 224.0
HFD2_k127_1612686_2 membrane-anchored protein conserved in bacteria - - - 0.000000000000000000000000000003327 134.0
HFD2_k127_1612686_3 Dimerisation domain - - - 0.000000000000000000000645 106.0
HFD2_k127_163559_0 Glycogen debranching enzyme - - - 1.107e-243 790.0
HFD2_k127_163559_1 PFAM FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 576.0
HFD2_k127_163559_10 conserved protein (COG2071) K09166 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008258 247.0
HFD2_k127_163559_11 HAD-hyrolase-like K06019 - 3.6.1.1 0.0000000000000000000000000000000000000000000000007467 182.0
HFD2_k127_163559_12 Belongs to the UPF0403 family - - - 0.000000000000000000000000000000000000000000000002528 177.0
HFD2_k127_163559_13 Low affinity iron permease - - - 0.000000000000000000000000000000000000000002487 163.0
HFD2_k127_163559_14 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000298 152.0
HFD2_k127_163559_15 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000000000000000003068 141.0
HFD2_k127_163559_16 - - - - 0.0000000000000000000000000000000001989 132.0
HFD2_k127_163559_17 Belongs to the UPF0337 (CsbD) family - - - 0.000000000000000000002893 100.0
HFD2_k127_163559_18 - - - - 0.00000000000000001755 83.0
HFD2_k127_163559_19 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000004271 91.0
HFD2_k127_163559_2 Dehydrogenase K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 477.0
HFD2_k127_163559_20 Protein of unknown function (DUF1328) - - - 0.00000000000003491 77.0
HFD2_k127_163559_21 - - - - 0.00000000005378 67.0
HFD2_k127_163559_3 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 470.0
HFD2_k127_163559_4 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005791 458.0
HFD2_k127_163559_5 aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006644 327.0
HFD2_k127_163559_6 phosphorelay signal transduction system K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 300.0
HFD2_k127_163559_7 Histidine kinase K02668,K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004212 276.0
HFD2_k127_163559_8 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006089 270.0
HFD2_k127_163559_9 Putative adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002083 263.0
HFD2_k127_1689766_0 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000815 346.0
HFD2_k127_1689766_1 8-amino-7-oxononanoate synthase K00639,K00652 - 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000006641 250.0
HFD2_k127_1689766_2 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000401 232.0
HFD2_k127_1689766_3 NmrA-like family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000003298 195.0
HFD2_k127_1689766_4 phosphatidate phosphatase activity K00901,K01096,K19302 - 2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.0000000000000000000000000000000000001009 158.0
HFD2_k127_1689766_5 PFAM blue (type 1) copper domain protein - - - 0.000001398 59.0
HFD2_k127_169140_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 470.0
HFD2_k127_169140_1 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000003993 200.0
HFD2_k127_169140_2 fibronectin type III domain protein - - - 0.000000000000000000000000000000006371 148.0
HFD2_k127_169140_3 usher protein - - - 0.0000000000000000000000000000004508 143.0
HFD2_k127_169140_4 GCN5-related N-acetyl-transferase K06975 - - 0.00000000000000001459 86.0
HFD2_k127_169140_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000002157 64.0
HFD2_k127_169140_6 SPTR Fibronectin type III domain protein - - - 0.00000000004677 78.0
HFD2_k127_1719773_0 ATPase involved in DNA repair - - - 0.000000000000000000001729 112.0
HFD2_k127_1719773_1 PQQ-like domain - - - 0.00000001378 68.0
HFD2_k127_1724375_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009318 625.0
HFD2_k127_1724375_1 Enoyl-CoA hydratase/isomerase K01661 - 4.1.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 453.0
HFD2_k127_1724375_10 - - - - 0.0001471 52.0
HFD2_k127_1724375_2 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 404.0
HFD2_k127_1724375_3 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001077 259.0
HFD2_k127_1724375_4 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000001374 222.0
HFD2_k127_1724375_5 Isochorismate synthase K02552 - 5.4.4.2 0.0000000000000000000000000000000000000000000003704 184.0
HFD2_k127_1724375_6 carboxylic ester hydrolase activity K08680 - 4.2.99.20 0.00000000000000000000000000000000001364 149.0
HFD2_k127_1724375_7 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000001768 124.0
HFD2_k127_1724375_8 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.000000000000000000000001094 110.0
HFD2_k127_1724375_9 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000004544 66.0
HFD2_k127_1767794_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.579e-275 876.0
HFD2_k127_1767794_1 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008935 611.0
HFD2_k127_1767794_10 Protein of unknown function (DUF503) K09764 - - 0.000000000000000008964 86.0
HFD2_k127_1767794_11 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family - - - 0.00000000004796 67.0
HFD2_k127_1767794_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 364.0
HFD2_k127_1767794_3 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000197 301.0
HFD2_k127_1767794_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000004568 211.0
HFD2_k127_1767794_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074 - - 0.00000000000000000000000000000000000000000000000000002703 214.0
HFD2_k127_1767794_6 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000002568 106.0
HFD2_k127_1767794_7 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000192 105.0
HFD2_k127_1767794_8 Preprotein translocase subunit TatD K03424 - - 0.000000000000000000000696 109.0
HFD2_k127_1767794_9 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000007672 94.0
HFD2_k127_1808672_0 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 374.0
HFD2_k127_1808672_1 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000009965 176.0
HFD2_k127_1808672_2 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000002624 168.0
HFD2_k127_1819116_0 Glycogen debranching enzyme - - - 5.751e-217 702.0
HFD2_k127_1819116_1 von Willebrand factor type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 610.0
HFD2_k127_1819116_2 Trehalase K03931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 598.0
HFD2_k127_1819116_3 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000009679 205.0
HFD2_k127_1819116_4 pilus organization - - - 0.0000000000000000000000000000000000001085 158.0
HFD2_k127_1819116_5 usher protein - - - 0.0000000000000000000000000005041 133.0
HFD2_k127_1819116_6 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000002168 81.0
HFD2_k127_1819116_8 CopG antitoxin of type II toxin-antitoxin system - - - 0.0000000000005482 72.0
HFD2_k127_1822165_0 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 0.0 1397.0
HFD2_k127_1822165_1 ABC transporter transmembrane region K11085 - - 1.901e-294 914.0
HFD2_k127_1822165_10 Domain of unknown function (DUF305) - - - 0.0000000000008812 69.0
HFD2_k127_1822165_12 - - - - 0.000008511 56.0
HFD2_k127_1822165_2 repeat protein - - - 6.508e-258 809.0
HFD2_k127_1822165_3 Ankyrin repeats (3 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 402.0
HFD2_k127_1822165_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007618 350.0
HFD2_k127_1822165_5 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000001112 234.0
HFD2_k127_1822165_6 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000007424 231.0
HFD2_k127_1822165_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000004159 173.0
HFD2_k127_1822165_8 DinB family - - - 0.0000000000000000000003365 111.0
HFD2_k127_1822165_9 Subtilase family - - - 0.000000000000000000001383 107.0
HFD2_k127_1830692_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 3.949e-303 955.0
HFD2_k127_1830692_1 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 2.423e-281 888.0
HFD2_k127_1830692_10 response regulator receiver K03413 - - 0.00000000000003769 83.0
HFD2_k127_1830692_2 Zn_pept - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 579.0
HFD2_k127_1830692_3 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 361.0
HFD2_k127_1830692_4 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000867 314.0
HFD2_k127_1830692_6 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000001003 219.0
HFD2_k127_1830692_8 MASE1 domain protein K07216 - - 0.000000000000000000000000000000000000000000000000000001815 213.0
HFD2_k127_1830692_9 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000000000000000000000235 122.0
HFD2_k127_1855294_0 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 374.0
HFD2_k127_1855294_1 ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004077 336.0
HFD2_k127_1855294_2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K00851,K00852,K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,2.7.1.15,5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000217 282.0
HFD2_k127_1855294_3 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000001447 218.0
HFD2_k127_1855294_4 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000006765 202.0
HFD2_k127_1855294_5 mitochondrial respiratory chain complex IV assembly K14998 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944 - 0.000000000000000000000000000005869 135.0
HFD2_k127_1855294_6 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.0000000000007309 70.0
HFD2_k127_1874350_0 xylulokinase activity K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 406.0
HFD2_k127_1874350_1 symporter activity K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 304.0
HFD2_k127_1874350_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004836 283.0
HFD2_k127_1874350_3 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.00000000000000000000000000000000000000000000000000000000000002014 230.0
HFD2_k127_1891877_0 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009624 482.0
HFD2_k127_1891877_1 Na dependent nucleoside transporter K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 440.0
HFD2_k127_1891877_2 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 313.0
HFD2_k127_1891877_3 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 310.0
HFD2_k127_1891877_4 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000122 282.0
HFD2_k127_1891877_5 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000283 234.0
HFD2_k127_1891877_6 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000000000008411 228.0
HFD2_k127_1891877_8 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 0.00000000002096 68.0
HFD2_k127_1930431_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K18307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002261 284.0
HFD2_k127_1930431_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000006007 216.0
HFD2_k127_1930431_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000003761 193.0
HFD2_k127_1930431_3 outer membrane efflux protein - - - 0.00000000000000002916 96.0
HFD2_k127_193836_0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 1.727e-203 642.0
HFD2_k127_193836_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 588.0
HFD2_k127_193836_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 368.0
HFD2_k127_193836_3 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH K22136 - - 0.000000000000000000000000000000000000000000000000000000000000002188 245.0
HFD2_k127_193836_4 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000151 188.0
HFD2_k127_193836_5 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000005056 134.0
HFD2_k127_193836_6 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00085 45.0
HFD2_k127_1965592_0 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 587.0
HFD2_k127_1965592_1 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005572 424.0
HFD2_k127_1965592_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 313.0
HFD2_k127_1965592_3 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000000125 187.0
HFD2_k127_1965592_4 - - - - 0.000000000000000000000000000000000000000001053 177.0
HFD2_k127_1965592_5 DAHP synthetase I family K01627 - 2.5.1.55 0.0000000000000000000000132 102.0
HFD2_k127_1965592_6 Lipopolysaccharide-assembly, LptC-related - - - 0.0009216 50.0
HFD2_k127_1979384_0 HELICc2 K03722 - 3.6.4.12 2.802e-276 891.0
HFD2_k127_1979384_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 530.0
HFD2_k127_1979384_2 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009504 419.0
HFD2_k127_1999933_0 ABC transporter transmembrane region K11085 - - 1.445e-238 752.0
HFD2_k127_1999933_1 Carbohydrate ABC transporter ATP-binding protein, CUT1 family K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 316.0
HFD2_k127_1999933_2 alpha,alpha-trehalase activity K01194,K03931 GO:0003674,GO:0003824,GO:0004553,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015926,GO:0016787,GO:0016798,GO:0033554,GO:0050896,GO:0051716 3.2.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 317.0
HFD2_k127_1999933_3 Diphthamide synthase - - - 0.00000000000000000000000000000000000000002793 160.0
HFD2_k127_1999933_4 - - - - 0.00002531 54.0
HFD2_k127_2025282_0 Zinc carboxypeptidase K14054 - - 0.0 1194.0
HFD2_k127_2025282_1 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 8.58e-214 683.0
HFD2_k127_2025282_10 - - - - 0.00000000000000000000000000000000000001257 148.0
HFD2_k127_2025282_11 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000001543 155.0
HFD2_k127_2025282_12 Lipopolysaccharide-assembly - - - 0.000000000000000000000000000000000004058 147.0
HFD2_k127_2025282_13 TIGRFAM hydrolase, TatD family K03424 - - 0.00000000000000000000000000001129 122.0
HFD2_k127_2025282_14 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000004711 120.0
HFD2_k127_2025282_15 - - - - 0.000000000000000000001007 95.0
HFD2_k127_2025282_16 Histidine kinase - - - 0.00000000000000000004159 106.0
HFD2_k127_2025282_17 - - - - 0.00000000000000000008862 89.0
HFD2_k127_2025282_18 - - - - 0.00000000000001891 81.0
HFD2_k127_2025282_19 - - - - 0.000000000004609 66.0
HFD2_k127_2025282_2 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009501 599.0
HFD2_k127_2025282_20 - - - - 0.000000000007863 65.0
HFD2_k127_2025282_21 - - - - 0.000000000134 66.0
HFD2_k127_2025282_22 - - - - 0.000000001102 68.0
HFD2_k127_2025282_23 - - - - 0.00000001451 57.0
HFD2_k127_2025282_25 ORF located using Blastx - - - 0.00000008406 56.0
HFD2_k127_2025282_26 photoreceptor activity K03413,K07684,K07689 - - 0.00001279 58.0
HFD2_k127_2025282_27 - - - - 0.00001841 52.0
HFD2_k127_2025282_28 - - - - 0.00002569 47.0
HFD2_k127_2025282_29 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.00006612 46.0
HFD2_k127_2025282_3 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008218 534.0
HFD2_k127_2025282_30 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0001384 54.0
HFD2_k127_2025282_4 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001298 280.0
HFD2_k127_2025282_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000004197 197.0
HFD2_k127_2025282_6 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000002749 167.0
HFD2_k127_2025282_7 - - - - 0.000000000000000000000000000000000000000196 152.0
HFD2_k127_2025282_8 Calcineurin-like phosphoesterase K03269 - 3.6.1.54 0.000000000000000000000000000000000000001036 157.0
HFD2_k127_2025282_9 Ham1 family K02428 - 3.6.1.66 0.000000000000000000000000000000000000001635 163.0
HFD2_k127_2068526_0 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K09461 - 1.14.13.40 7.86e-321 1017.0
HFD2_k127_2068526_1 Imidazolonepropionase and related - - - 1.384e-223 722.0
HFD2_k127_2068526_10 fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 361.0
HFD2_k127_2068526_11 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 357.0
HFD2_k127_2068526_12 dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 368.0
HFD2_k127_2068526_13 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 341.0
HFD2_k127_2068526_14 tryptophan 2,3-dioxygenase activity K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 347.0
HFD2_k127_2068526_15 ATP ADP translocase K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 331.0
HFD2_k127_2068526_16 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 330.0
HFD2_k127_2068526_17 Acetamidase/Formamidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 308.0
HFD2_k127_2068526_18 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002513 281.0
HFD2_k127_2068526_19 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000256 251.0
HFD2_k127_2068526_2 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 2.525e-220 698.0
HFD2_k127_2068526_20 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000005181 266.0
HFD2_k127_2068526_21 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019,K07535 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.30 0.00000000000000000000000000000000000000000000000000005403 198.0
HFD2_k127_2068526_22 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000002942 140.0
HFD2_k127_2068526_23 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000004092 141.0
HFD2_k127_2068526_24 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000592 138.0
HFD2_k127_2068526_25 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000002608 100.0
HFD2_k127_2068526_27 Membrane - - - 0.0000001036 60.0
HFD2_k127_2068526_3 lysine biosynthetic process via aminoadipic acid - - - 1.474e-209 691.0
HFD2_k127_2068526_4 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008644 545.0
HFD2_k127_2068526_5 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008807 470.0
HFD2_k127_2068526_6 COG1914 Mn2 and Fe2 transporters of the NRAMP family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 452.0
HFD2_k127_2068526_7 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 420.0
HFD2_k127_2068526_8 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 376.0
HFD2_k127_2068526_9 COG1680 Beta-lactamase class C and other penicillin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 385.0
HFD2_k127_2084089_0 Zinc-binding dehydrogenase K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 317.0
HFD2_k127_2084089_1 PFAM Glycoside hydrolase 15-related - - - 0.00000000000000000000000000000000000000000000000000000000000000000003101 238.0
HFD2_k127_2120929_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 492.0
HFD2_k127_2120929_1 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 320.0
HFD2_k127_2120929_2 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001235 262.0
HFD2_k127_2120929_3 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001669 254.0
HFD2_k127_2120929_4 asparagine synthase - - - 0.000000000000000000000000000000000000000000000000000000000000002072 236.0
HFD2_k127_2120929_5 Glycosyltransferase K20534 - - 0.000000000000000000000000000000000000000000000000003884 199.0
HFD2_k127_2120929_6 Capsular polysaccharide biosynthesis protein CapK K01912 - 6.2.1.30 0.0000000000000000000000000000000000001982 157.0
HFD2_k127_2120929_7 integral membrane protein K07027 - - 0.00000000008833 74.0
HFD2_k127_2120929_8 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000001587 74.0
HFD2_k127_2164114_0 PAS fold - - - 5.749e-213 680.0
HFD2_k127_2164114_1 Histidine kinase HAMP - - - 0.0000000000000000000000000000000000000000000000000000000000001857 230.0
HFD2_k127_2164114_2 Pfam Response regulator receiver - - - 0.0000000000000000000004796 101.0
HFD2_k127_218829_0 Acetyl xylan esterase (AXE1) - - - 1.874e-294 918.0
HFD2_k127_218829_1 Pyrimidine nucleoside phosphorylase C-terminal domain K00756 - 2.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009054 538.0
HFD2_k127_218829_2 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 433.0
HFD2_k127_218829_3 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 339.0
HFD2_k127_218829_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000001548 183.0
HFD2_k127_218829_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter - - - 0.0000000000000000000000000000000000000000000000756 173.0
HFD2_k127_218829_6 Phosphoribosyl transferase domain K07101 - - 0.0000000000000000000000000000000000000000000001157 173.0
HFD2_k127_218829_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000002784 146.0
HFD2_k127_218829_8 4-vinyl reductase, 4VR - - - 0.000000000000000000004837 100.0
HFD2_k127_218829_9 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain K11527 - 2.7.13.3 0.00000003718 65.0
HFD2_k127_2240014_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 362.0
HFD2_k127_2240014_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007637 278.0
HFD2_k127_2240014_2 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000003394 262.0
HFD2_k127_2240014_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000008031 224.0
HFD2_k127_2240014_4 Glutathione peroxidase - - - 0.0000000000000000000000000000000000009305 156.0
HFD2_k127_2240014_5 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00000000000000000001758 104.0
HFD2_k127_2240014_6 DinB superfamily - - - 0.0000000003732 64.0
HFD2_k127_2262213_0 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00174 - 1.2.7.11,1.2.7.3 2.111e-249 794.0
HFD2_k127_2262213_1 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 5.381e-223 709.0
HFD2_k127_2262213_10 - - - - 0.000000000000001798 90.0
HFD2_k127_2262213_11 Regulatory protein, FmdB family - - - 0.0000004751 54.0
HFD2_k127_2262213_12 BlaR1 peptidase M56 - - - 0.000192 52.0
HFD2_k127_2262213_2 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 498.0
HFD2_k127_2262213_3 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 437.0
HFD2_k127_2262213_4 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 436.0
HFD2_k127_2262213_5 PFAM Thiolase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 421.0
HFD2_k127_2262213_6 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 335.0
HFD2_k127_2262213_7 electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001739 265.0
HFD2_k127_2262213_8 Regulator of chromosome condensation (RCC1) repeat - - - 0.0000000000000000000000000000000000000000001025 180.0
HFD2_k127_2262213_9 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000001197 136.0
HFD2_k127_2281471_1 mRNA cleavage K19158 - - 0.000000000001084 72.0
HFD2_k127_2299867_0 Sortilin, neurotensin receptor 3, - - - 0.0 1485.0
HFD2_k127_2299867_1 Carbohydrate family 9 binding domain-like - - - 0.0 1061.0
HFD2_k127_2299867_2 Protein of unknown function (DUF2891) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000624 477.0
HFD2_k127_2299867_3 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 428.0
HFD2_k127_2299867_4 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000007972 254.0
HFD2_k127_2299867_5 NifU-like N terminal domain K04488 - - 0.0000000000000000000002134 110.0
HFD2_k127_2299867_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000004579 76.0
HFD2_k127_230814_0 Bacterial membrane protein, YfhO - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 452.0
HFD2_k127_230814_1 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000007842 231.0
HFD2_k127_230814_2 Hexapeptide repeat of succinyl-transferase K00661 - 2.3.1.79 0.00000000000000000000000000000000001406 142.0
HFD2_k127_230814_3 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000001201 141.0
HFD2_k127_230814_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000001082 135.0
HFD2_k127_230814_5 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.00000000000000000000002182 115.0
HFD2_k127_230814_6 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process - - - 0.0000000000000000001058 103.0
HFD2_k127_230814_7 PFAM Methyltransferase type 11 - - - 0.000000000000006998 81.0
HFD2_k127_2314630_0 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000922 355.0
HFD2_k127_2314630_1 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009986 320.0
HFD2_k127_2314630_2 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001265 282.0
HFD2_k127_2314630_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000000000003381 173.0
HFD2_k127_2314630_4 Glycosyl hydrolases family 2, TIM barrel domain K01190 - 3.2.1.23 0.00000000000000000000000000000008983 128.0
HFD2_k127_2314630_5 Nucleotidyl transferase - - - 0.0000000000000000000000027 109.0
HFD2_k127_2314630_6 - - - - 0.00000000000000000006315 94.0
HFD2_k127_2314630_7 synthase - - - 0.00001491 57.0
HFD2_k127_2381350_0 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007585 439.0
HFD2_k127_2381350_1 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 425.0
HFD2_k127_2381350_2 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 377.0
HFD2_k127_2381350_3 diguanylate cyclase K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 335.0
HFD2_k127_2381350_4 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 309.0
HFD2_k127_2381350_5 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000424 238.0
HFD2_k127_2381350_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000009709 213.0
HFD2_k127_2381350_7 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000002109 192.0
HFD2_k127_2381350_8 Tetracycline repressor, C-terminal all-alpha domain K22106 - - 0.00000000000008783 79.0
HFD2_k127_2381350_9 Surface antigen - - - 0.0000002906 62.0
HFD2_k127_239746_0 Regulator of chromosome condensation (RCC1) repeat - - - 0.0000000000000000000000000000000006189 147.0
HFD2_k127_239746_1 chitinase K01183 - 3.2.1.14 0.000000001296 70.0
HFD2_k127_239746_2 Belongs to the ClpA ClpB family K03696 - - 0.000000004748 63.0
HFD2_k127_2465530_0 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000411 261.0
HFD2_k127_2465530_1 Belongs to the metal hydrolase YfiT family - - - 0.00000000000000000000000000000000000000000000000000000000000006513 222.0
HFD2_k127_2465530_2 Capsule assembly protein Wzi - - - 0.000000001282 71.0
HFD2_k127_2465530_3 Capsule assembly protein Wzi - - - 0.000001851 59.0
HFD2_k127_2527476_0 Flavin containing amine oxidoreductase - - - 1.032e-194 625.0
HFD2_k127_2527476_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000005654 199.0
HFD2_k127_2527476_2 glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000003178 154.0
HFD2_k127_2527476_3 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000005192 128.0
HFD2_k127_2527476_4 Glycosyl transferases group 1 - - - 0.0000001749 55.0
HFD2_k127_2531268_0 Glycogen debranching enzyme - - - 1.448e-238 764.0
HFD2_k127_2531268_1 Oxidoreductase - - - 5.913e-228 734.0
HFD2_k127_2531268_10 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000008472 192.0
HFD2_k127_2531268_11 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000002757 177.0
HFD2_k127_2531268_12 Thiol-disulfide oxidoreductase - - - 0.00000000000000000000000000000001853 136.0
HFD2_k127_2531268_13 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000006176 143.0
HFD2_k127_2531268_14 Cysteine-rich CPXCG - - - 0.0000000000000000000000002999 115.0
HFD2_k127_2531268_15 - - - - 0.0000000000000000002276 99.0
HFD2_k127_2531268_16 Acetyltransferase (GNAT) family - - - 0.00000000000000002935 88.0
HFD2_k127_2531268_17 - - - - 0.00000000000003681 85.0
HFD2_k127_2531268_19 - - - - 0.0001124 46.0
HFD2_k127_2531268_2 Sodium:sulfate symporter transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009983 593.0
HFD2_k127_2531268_3 Alpha-L-fucosidase K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 499.0
HFD2_k127_2531268_4 Glycine cleavage T-protein C-terminal barrel domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 428.0
HFD2_k127_2531268_5 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 369.0
HFD2_k127_2531268_6 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007961 356.0
HFD2_k127_2531268_7 Thi4 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008818 335.0
HFD2_k127_2531268_8 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 299.0
HFD2_k127_2531268_9 Psort location CytoplasmicMembrane, score 10.00 K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001289 259.0
HFD2_k127_2540738_0 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0 1049.0
HFD2_k127_2540738_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 553.0
HFD2_k127_2540738_2 Including oxidative damage repair enzymes - - - 0.000000000000000000000000001373 119.0
HFD2_k127_2540738_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000004053 77.0
HFD2_k127_2548944_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.711e-200 629.0
HFD2_k127_2548944_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 507.0
HFD2_k127_2548944_10 PBS lyase HEAT-like repeat - - - 0.0000000000009755 80.0
HFD2_k127_2548944_11 peptidyl-tyrosine sulfation - - - 0.0000004372 63.0
HFD2_k127_2548944_2 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 491.0
HFD2_k127_2548944_3 major pilin protein fima - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008641 355.0
HFD2_k127_2548944_4 Nucleotidyl transferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 323.0
HFD2_k127_2548944_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001352 259.0
HFD2_k127_2548944_6 Sugar nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000002543 235.0
HFD2_k127_2548944_7 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.000000000000000000000000000000000000001165 165.0
HFD2_k127_2548944_8 Roadblock/LC7 domain K07131 - - 0.0000000000000000000000005258 109.0
HFD2_k127_2548944_9 - - - - 0.0000000000000002226 86.0
HFD2_k127_2552998_0 MMPL family - - - 4.726e-290 922.0
HFD2_k127_2552998_1 Belongs to the sigma-70 factor family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 563.0
HFD2_k127_2552998_10 MerR, DNA binding K13639 - - 0.000000000000001189 81.0
HFD2_k127_2552998_11 ketosteroid isomerase - - - 0.000000000004827 78.0
HFD2_k127_2552998_13 NADPH:quinone reductase activity - - - 0.00002234 57.0
HFD2_k127_2552998_2 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 390.0
HFD2_k127_2552998_3 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007701 284.0
HFD2_k127_2552998_4 PFAM DGPFAETKE family protein - - - 0.0000000000000000000000000000000000000000000000000000000004383 211.0
HFD2_k127_2552998_5 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000002446 219.0
HFD2_k127_2552998_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000009592 124.0
HFD2_k127_2552998_7 - - - - 0.0000000000000000000000008106 114.0
HFD2_k127_2552998_8 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.000000000000000000000001575 117.0
HFD2_k127_2552998_9 DNA-binding transcription factor activity - - - 0.0000000000000000000006381 103.0
HFD2_k127_2554406_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 606.0
HFD2_k127_2554406_1 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 562.0
HFD2_k127_2554406_2 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 385.0
HFD2_k127_2554406_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005373 296.0
HFD2_k127_2554406_4 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001508 285.0
HFD2_k127_2644269_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 3.581e-205 649.0
HFD2_k127_2644269_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 569.0
HFD2_k127_2644269_10 MgtC family K07507 - - 0.0000000000000000000000000000001024 134.0
HFD2_k127_2644269_11 Zincin-like metallopeptidase - - - 0.0000000000000000003808 96.0
HFD2_k127_2644269_2 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 451.0
HFD2_k127_2644269_3 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 402.0
HFD2_k127_2644269_4 metalloendopeptidase activity K08602 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 414.0
HFD2_k127_2644269_5 CarboxypepD_reg-like domain K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 359.0
HFD2_k127_2644269_6 Dihydrodipicolinate synthetase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002712 243.0
HFD2_k127_2644269_7 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000279 250.0
HFD2_k127_2644269_8 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000001173 233.0
HFD2_k127_2644269_9 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000002082 203.0
HFD2_k127_266939_0 Beta-ketoacyl synthase, C-terminal domain - - - 3.192e-228 717.0
HFD2_k127_266939_1 Serine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 388.0
HFD2_k127_266939_2 DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 346.0
HFD2_k127_2713226_0 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 417.0
HFD2_k127_2713226_1 TIGRFAM phosphate ABC transporter, phosphate-binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 377.0
HFD2_k127_2713226_10 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000007566 185.0
HFD2_k127_2713226_11 phosphate-selective porin O and P K07221 - - 0.0000317 56.0
HFD2_k127_2713226_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 327.0
HFD2_k127_2713226_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 323.0
HFD2_k127_2713226_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 311.0
HFD2_k127_2713226_5 HAMP domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 333.0
HFD2_k127_2713226_6 Transcriptional regulatory protein, C terminal K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 299.0
HFD2_k127_2713226_7 Phosphate transport system permease protein PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008474 278.0
HFD2_k127_2713226_8 negative regulation of phosphate transmembrane transport K02039 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0000000000000000000000000000000000000000000000000000000001674 221.0
HFD2_k127_2713226_9 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000001617 180.0
HFD2_k127_2738644_0 Belongs to the globin family - - - 0.0000000000000000000000000000000000000000000000000000000000007498 213.0
HFD2_k127_2738644_1 Transposase DDE domain - - - 0.000000000000000000000000007067 115.0
HFD2_k127_2738644_2 DDE_Tnp_1-associated - - - 0.0000000003901 73.0
HFD2_k127_273930_0 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 332.0
HFD2_k127_273930_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001082 284.0
HFD2_k127_273930_2 ECF sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002119 270.0
HFD2_k127_273930_3 membrane K11622 - - 0.0000000000000000000000000000000000002175 160.0
HFD2_k127_273930_4 transglycosylase associated protein - - - 0.00000000000000000000000000001002 125.0
HFD2_k127_273930_5 Polymer-forming cytoskeletal - - - 0.0000000000000001021 93.0
HFD2_k127_273930_6 peptidase U32 - - - 0.000000000000001592 79.0
HFD2_k127_273930_7 PQQ enzyme repeat - - - 0.000000000002428 78.0
HFD2_k127_273930_8 Bacterial Ig-like domain 2 - - - 0.0000002517 63.0
HFD2_k127_2752067_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 4.039e-201 663.0
HFD2_k127_2752067_1 Belongs to the peptidase S51 family K05995 - 3.4.13.21 0.00000000000000000000000000000000000000000000000000000000000000000000001979 248.0
HFD2_k127_2752067_2 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000001665 162.0
HFD2_k127_2752067_3 AMMECR1 K09141 - - 0.000000000000000000000000000000001083 149.0
HFD2_k127_2752067_4 DinB superfamily - - - 0.000000000000001102 88.0
HFD2_k127_2752067_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K21136 - - 0.000000000000005378 86.0
HFD2_k127_2752067_6 Glycine cleavage T-protein C-terminal barrel domain - - - 0.000000000002391 71.0
HFD2_k127_2769319_0 Bacterial protein of unknown function (DUF853) K06915 - - 3.557e-244 762.0
HFD2_k127_2769319_1 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 568.0
HFD2_k127_2769319_10 Phospholipase/Carboxylesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000321 222.0
HFD2_k127_2769319_11 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000002632 228.0
HFD2_k127_2769319_12 Methyltransferase small domain K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000006218 193.0
HFD2_k127_2769319_13 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000002901 165.0
HFD2_k127_2769319_14 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000005717 157.0
HFD2_k127_2769319_15 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0000000000000000000000000000000001428 136.0
HFD2_k127_2769319_16 Rossmann-like domain - - - 0.00000000000000000000000000000002166 144.0
HFD2_k127_2769319_17 PFAM OsmC family protein - - - 0.00000000000000000000000001633 119.0
HFD2_k127_2769319_18 Curli production assembly/transport component CsgG - - - 0.000000000000000000000006737 110.0
HFD2_k127_2769319_19 Binds the 23S rRNA K02909 - - 0.00000000000000000000006415 109.0
HFD2_k127_2769319_2 COG1055 Na H antiporter NhaD and related arsenite - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 544.0
HFD2_k127_2769319_20 Control of competence regulator ComK, YlbF/YmcA - - - 0.00000000000000007471 93.0
HFD2_k127_2769319_3 MFS/sugar transport protein K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 487.0
HFD2_k127_2769319_4 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 467.0
HFD2_k127_2769319_5 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007766 460.0
HFD2_k127_2769319_6 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 436.0
HFD2_k127_2769319_7 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 306.0
HFD2_k127_2769319_8 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000001596 229.0
HFD2_k127_2769319_9 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000000000000000000000000000000000000000000000000000000000007301 223.0
HFD2_k127_2776898_0 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 525.0
HFD2_k127_2776898_1 PFAM FAD dependent oxidoreductase K15736 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 374.0
HFD2_k127_2776898_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 315.0
HFD2_k127_2776898_3 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 319.0
HFD2_k127_2776898_4 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000002962 281.0
HFD2_k127_2776898_5 transporter K07238,K11021,K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000155 254.0
HFD2_k127_2776898_6 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000005608 199.0
HFD2_k127_2776898_7 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000002013 185.0
HFD2_k127_2784403_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 338.0
HFD2_k127_2784403_1 Quinoprotein glucose dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 310.0
HFD2_k127_2784403_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004186 317.0
HFD2_k127_2784403_3 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004545 297.0
HFD2_k127_2784403_4 rRNA (guanine-N2-)-methyltransferase activity K08316,K15257 - 2.1.1.171 0.0000000000000000000000000008609 121.0
HFD2_k127_2784403_5 - - - - 0.0000000000000001309 88.0
HFD2_k127_2784403_6 Bacterial Ig-like domain 2 - - - 0.0000002081 63.0
HFD2_k127_2845314_0 protein kinase activity K12132 - 2.7.11.1 1.229e-208 682.0
HFD2_k127_2845314_1 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 558.0
HFD2_k127_2845314_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 413.0
HFD2_k127_2845314_3 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 314.0
HFD2_k127_2845314_4 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.000000000000000000000000000000000000000000000000000000000000000000000000000001042 276.0
HFD2_k127_2845314_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008554 242.0
HFD2_k127_2845314_6 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000009415 190.0
HFD2_k127_2845314_7 response regulator - - - 0.000000000000000000000000000000000000000000106 163.0
HFD2_k127_2929066_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 4.017e-220 691.0
HFD2_k127_2929066_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 505.0
HFD2_k127_2929066_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000002204 75.0
HFD2_k127_2929066_2 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 391.0
HFD2_k127_2929066_3 Polyprenyl synthetase K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 351.0
HFD2_k127_2929066_4 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005861 337.0
HFD2_k127_2929066_5 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000002225 182.0
HFD2_k127_2929066_6 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.0000000000000000000000000000000000000000001307 174.0
HFD2_k127_2929066_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000006927 157.0
HFD2_k127_2929066_8 Domain of unknown function (DUF4321) - - - 0.000000000000000000000000205 107.0
HFD2_k127_2929066_9 Tetratricopeptide repeat - - - 0.000000000000000000001333 110.0
HFD2_k127_2942623_0 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 572.0
HFD2_k127_2942623_1 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 527.0
HFD2_k127_2942623_10 Copper binding proteins, plastocyanin/azurin family K02638 - - 0.00000000000000000000003402 106.0
HFD2_k127_2942623_2 VWA domain containing CoxE-like protein K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 374.0
HFD2_k127_2942623_3 Pfam Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000568 229.0
HFD2_k127_2942623_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000371 227.0
HFD2_k127_2942623_5 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000008553 188.0
HFD2_k127_2942623_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000145 167.0
HFD2_k127_2942623_7 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000007584 124.0
HFD2_k127_2942623_8 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000004099 131.0
HFD2_k127_2942623_9 cytochrome c - - - 0.000000000000000000000002145 111.0
HFD2_k127_2947947_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 359.0
HFD2_k127_2947947_1 aminopeptidase N - - - 0.0000000000000000000000000000000003008 148.0
HFD2_k127_2947947_2 protein kinase activity K12132 - 2.7.11.1 0.00000006833 64.0
HFD2_k127_2978937_0 Major Facilitator Superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 518.0
HFD2_k127_2978937_1 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000001417 158.0
HFD2_k127_2978937_2 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000298 149.0
HFD2_k127_3039894_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 1.969e-214 671.0
HFD2_k127_3039894_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 488.0
HFD2_k127_3039894_10 Maf-like protein K06287 - - 0.00000000000000000007466 91.0
HFD2_k127_3039894_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 436.0
HFD2_k127_3039894_3 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004509 413.0
HFD2_k127_3039894_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 371.0
HFD2_k127_3039894_5 O-acyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 344.0
HFD2_k127_3039894_6 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000003148 291.0
HFD2_k127_3039894_7 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000002104 167.0
HFD2_k127_3039894_8 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000003467 115.0
HFD2_k127_3039894_9 - - - - 0.000000000000000000000001157 117.0
HFD2_k127_3066704_0 Amidohydrolase family - - - 0.0 1307.0
HFD2_k127_3066704_1 Amidohydrolase family - - - 4.802e-281 884.0
HFD2_k127_3085717_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 475.0
HFD2_k127_3085717_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009942 299.0
HFD2_k127_3085717_2 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000003301 204.0
HFD2_k127_3085717_3 protein kinase activity - - - 0.000000000000000000000000000000003332 138.0
HFD2_k127_3086629_0 dipeptidyl-peptidase activity K06978 - - 1.282e-209 669.0
HFD2_k127_3086629_1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 549.0
HFD2_k127_3086629_2 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 551.0
HFD2_k127_3086629_3 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004276 285.0
HFD2_k127_3086629_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000151 248.0
HFD2_k127_3086629_5 phosphoribosyltransferase K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000008296 208.0
HFD2_k127_3086629_6 AlkA N-terminal domain K13529 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000001155 203.0
HFD2_k127_3086629_7 RHS protein - - - 0.0000000000000002185 93.0
HFD2_k127_3086629_8 Belongs to the universal stress protein A family - - - 0.000001846 60.0
HFD2_k127_3087505_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008228 481.0
HFD2_k127_3087505_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 463.0
HFD2_k127_3087505_10 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000002712 164.0
HFD2_k127_3087505_11 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000001114 142.0
HFD2_k127_3087505_12 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000001453 93.0
HFD2_k127_3087505_13 Preprotein translocase subunit K03210 - - 0.000000000000001573 87.0
HFD2_k127_3087505_14 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00001995 55.0
HFD2_k127_3087505_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 377.0
HFD2_k127_3087505_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006946 327.0
HFD2_k127_3087505_4 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 296.0
HFD2_k127_3087505_5 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000002854 248.0
HFD2_k127_3087505_6 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000001527 240.0
HFD2_k127_3087505_7 DnaB-like helicase C terminal domain K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000008199 196.0
HFD2_k127_3087505_8 Glycosyl transferase, family 9 K02843 - - 0.0000000000000000000000000000000000000000000000001405 188.0
HFD2_k127_3087505_9 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000003097 179.0
HFD2_k127_311441_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 417.0
HFD2_k127_311441_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001055 250.0
HFD2_k127_311441_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000009147 124.0
HFD2_k127_3223369_0 esterase - - - 3.305e-264 824.0
HFD2_k127_3223369_1 Multicopper oxidase K22348 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 450.0
HFD2_k127_3223369_2 cAMP biosynthetic process K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 466.0
HFD2_k127_3223369_3 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 392.0
HFD2_k127_3223369_4 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001755 262.0
HFD2_k127_3223369_5 - - - - 0.000000000000001524 84.0
HFD2_k127_3223369_6 translation initiation factor activity K06996 - - 0.00000004169 56.0
HFD2_k127_3244831_0 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002221 263.0
HFD2_k127_3244831_1 Belongs to the arginase family K01476 - 3.5.3.1 0.000000000000000000000000000000000000000000000000000000001224 209.0
HFD2_k127_3244831_2 response regulator - - - 0.0000000000004363 73.0
HFD2_k127_3244831_3 ACT domain protein - - - 0.000000000131 68.0
HFD2_k127_3263336_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000522 466.0
HFD2_k127_3263336_1 PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 322.0
HFD2_k127_3263336_2 UDP binding domain K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000001102 244.0
HFD2_k127_3264559_0 Pyruvate formate lyase-activating protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006099 583.0
HFD2_k127_3264559_1 Domain of unknown function (DUF4153) - - - 0.000000000000000006461 96.0
HFD2_k127_3435708_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 602.0
HFD2_k127_3435708_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000008073 227.0
HFD2_k127_3435708_2 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000001002 229.0
HFD2_k127_3435708_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000009993 198.0
HFD2_k127_3435708_4 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000001539 189.0
HFD2_k127_3435708_5 Septum formation initiator K05589 - - 0.0000003423 61.0
HFD2_k127_3436319_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 461.0
HFD2_k127_3447316_0 Penicillin amidase K01434 - 3.5.1.11 2.535e-246 773.0
HFD2_k127_3447316_1 aminopeptidase N - - - 1.144e-233 728.0
HFD2_k127_3447316_2 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 371.0
HFD2_k127_3447316_3 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000000000000000000000002061 178.0
HFD2_k127_3447316_4 Penicillin amidase - - - 0.000000000000000000000000000000000000000000000001589 184.0
HFD2_k127_3447316_5 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000001511 187.0
HFD2_k127_3447682_0 CarboxypepD_reg-like domain - - - 0.00000008756 65.0
HFD2_k127_3463707_0 Tricorn protease homolog K08676 - - 3.425e-244 764.0
HFD2_k127_3463707_1 - - - - 0.000000000000000000000000000000000000000000004708 171.0
HFD2_k127_3483193_0 Vitamin B12 dependent methionine synthase, activation K00548 - 2.1.1.13 0.0 1633.0
HFD2_k127_3483193_1 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 5.853e-213 678.0
HFD2_k127_3483193_10 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.0000000000000000000000000004471 118.0
HFD2_k127_3483193_11 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000005331 115.0
HFD2_k127_3483193_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000002302 119.0
HFD2_k127_3483193_13 Belongs to the UPF0235 family K09131 - - 0.0000000000003568 70.0
HFD2_k127_3483193_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 607.0
HFD2_k127_3483193_3 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007173 537.0
HFD2_k127_3483193_4 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009278 492.0
HFD2_k127_3483193_5 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 449.0
HFD2_k127_3483193_6 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 409.0
HFD2_k127_3483193_7 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 357.0
HFD2_k127_3483193_8 PFAM ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 349.0
HFD2_k127_3483193_9 Esterase PHB depolymerase K03932 - - 0.0000000000000000000000000000000000000005834 164.0
HFD2_k127_3522753_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 2.036e-202 662.0
HFD2_k127_3522753_1 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002487 250.0
HFD2_k127_3522753_2 peptidase activity, acting on L-amino acid peptides K20276 - - 0.0000000005009 74.0
HFD2_k127_3522753_3 Phosphoribosyl transferase domain K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00001071 56.0
HFD2_k127_3536413_0 Peptidase family M1 domain - - - 1.712e-221 709.0
HFD2_k127_3536413_1 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 4.258e-219 695.0
HFD2_k127_3536413_10 PFAM Cytochrome C - - - 0.000000000000000000000000000000000000000000000000000000000006682 220.0
HFD2_k127_3536413_11 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000001094 209.0
HFD2_k127_3536413_12 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000000000000000006669 203.0
HFD2_k127_3536413_13 hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000007604 193.0
HFD2_k127_3536413_14 ApaG domain K06195 - - 0.0000000000000000000000000000000000000000000000000003655 188.0
HFD2_k127_3536413_15 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.0000000000000000000000000000000000000000000001422 176.0
HFD2_k127_3536413_16 - - - - 0.00000000000000000000000000000000000001446 155.0
HFD2_k127_3536413_17 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000001667 144.0
HFD2_k127_3536413_18 PHP-associated - - - 0.000000000000000000000000000000005879 137.0
HFD2_k127_3536413_19 aminopeptidase N - - - 0.000248 52.0
HFD2_k127_3536413_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 511.0
HFD2_k127_3536413_3 Aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 461.0
HFD2_k127_3536413_4 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 472.0
HFD2_k127_3536413_5 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 319.0
HFD2_k127_3536413_6 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 308.0
HFD2_k127_3536413_7 Proton-conducting membrane transporter K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 311.0
HFD2_k127_3536413_8 glutamate carboxypeptidase K01301 - 3.4.17.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008146 273.0
HFD2_k127_3536413_9 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000006708 230.0
HFD2_k127_3557198_0 Penicillin binding protein transpeptidase domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 400.0
HFD2_k127_3557198_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006556 313.0
HFD2_k127_3557198_2 Tetratricopeptide repeat - - - 0.000000000000000009423 98.0
HFD2_k127_3557198_4 - - - - 0.00004872 46.0
HFD2_k127_3617148_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006984 424.0
HFD2_k127_3617148_1 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 331.0
HFD2_k127_3617148_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 319.0
HFD2_k127_3617148_3 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000466 273.0
HFD2_k127_3617148_4 ECF sigma factor K03088 - - 0.000000002177 59.0
HFD2_k127_3618079_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 5.874e-231 728.0
HFD2_k127_3618079_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009336 406.0
HFD2_k127_3618079_2 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 304.0
HFD2_k127_3618079_3 (FHA) domain - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 - 0.000000000000000003359 89.0
HFD2_k127_3618079_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000003679 86.0
HFD2_k127_3618079_5 Zinc-dependent metalloprotease - - - 0.00005582 55.0
HFD2_k127_3713345_0 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002182 260.0
HFD2_k127_3713345_1 LysM domain - - - 0.00000000000000000000000000000000000000000000001648 179.0
HFD2_k127_3713345_2 Calcineurin-like phosphoesterase K01077 - 3.1.3.1 0.000000000000000000000000000000000000000000004338 181.0
HFD2_k127_3716899_0 heavy metal translocating P-type ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 1.73e-255 806.0
HFD2_k127_3810305_0 Heparinase II/III-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009479 466.0
HFD2_k127_3810305_1 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007429 308.0
HFD2_k127_3810305_2 Molybdopterin oxidoreductase Fe4S4 domain K08357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 297.0
HFD2_k127_3810305_3 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003853 297.0
HFD2_k127_3810305_4 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000003653 228.0
HFD2_k127_3810305_5 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.200,3.5.1.19,6.1.1.16 0.0000000000000000000000000000000000000000000000000000000007877 214.0
HFD2_k127_3810305_6 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000007707 161.0
HFD2_k127_3810305_7 GHMP kinases N terminal domain K07031 - 2.7.1.168 0.00000000000000000007381 94.0
HFD2_k127_3823952_0 Belongs to the carbamoyltransferase HypF family K04656 - - 2.349e-204 662.0
HFD2_k127_3823952_1 Hydrogenase formation hypA family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 513.0
HFD2_k127_3823952_2 PFAM cobalamin synthesis protein P47K K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000006252 231.0
HFD2_k127_3823952_3 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000069 171.0
HFD2_k127_3823952_4 - - - - 0.00000000000000000000000001222 109.0
HFD2_k127_3823952_5 HupF/HypC family K04653 - - 0.000000000000000000001352 98.0
HFD2_k127_3823952_6 - - - - 0.0000004215 55.0
HFD2_k127_3827234_0 56kDa selenium binding protein (SBP56) K17285 - - 3.146e-231 723.0
HFD2_k127_3827234_1 Alpha galactosidase A C-terminal beta sandwich domain K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 460.0
HFD2_k127_3827234_10 - - - - 0.000000313 55.0
HFD2_k127_3827234_2 Proline racemase K01777 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016855,GO:0018112,GO:0019752,GO:0036361,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047661,GO:0050346,GO:0071704,GO:1901564 5.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 385.0
HFD2_k127_3827234_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000154 216.0
HFD2_k127_3827234_4 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000001044 225.0
HFD2_k127_3827234_5 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000126 198.0
HFD2_k127_3827234_6 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000005147 177.0
HFD2_k127_3827234_7 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.000000000000000000000000000000000001807 145.0
HFD2_k127_3827234_9 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000001925 76.0
HFD2_k127_3900098_0 Glycosyl hydrolases family 39 K01198 - 3.2.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 400.0
HFD2_k127_3900098_1 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004351 244.0
HFD2_k127_4010323_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 3.741e-312 979.0
HFD2_k127_4010323_1 Amidohydrolase family - - - 5.361e-206 653.0
HFD2_k127_4010323_10 56kDa selenium binding protein (SBP56) K17285 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 307.0
HFD2_k127_4010323_11 FES K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000001773 244.0
HFD2_k127_4010323_12 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000001324 230.0
HFD2_k127_4010323_13 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000001705 238.0
HFD2_k127_4010323_14 ATPases associated with a variety of cellular activities K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000001281 230.0
HFD2_k127_4010323_15 Protein of unknown function (DUF2167) - - - 0.000000000000000000000000000000000000000000000000000000000003525 220.0
HFD2_k127_4010323_16 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000003287 216.0
HFD2_k127_4010323_17 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000005053 203.0
HFD2_k127_4010323_18 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000004922 191.0
HFD2_k127_4010323_19 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000007176 148.0
HFD2_k127_4010323_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 620.0
HFD2_k127_4010323_20 - - - - 0.000000000000000000000000000000000004501 148.0
HFD2_k127_4010323_21 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000000000000001483 127.0
HFD2_k127_4010323_22 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K15520 - 2.3.1.189 0.0000000000000000000000000006976 121.0
HFD2_k127_4010323_23 Paraquat-inducible protein A - - - 0.0000000000000000000000002104 116.0
HFD2_k127_4010323_24 - - - - 0.00000000000000000000001036 111.0
HFD2_k127_4010323_25 Protein of unknown function (DUF559) - - - 0.0000000000000000000315 104.0
HFD2_k127_4010323_26 Phospholipase K07001 - - 0.000000000000000004198 96.0
HFD2_k127_4010323_28 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000001149 75.0
HFD2_k127_4010323_29 MlaD protein K02067 - - 0.0000001575 62.0
HFD2_k127_4010323_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 568.0
HFD2_k127_4010323_30 - - - - 0.00001012 59.0
HFD2_k127_4010323_31 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.00002959 55.0
HFD2_k127_4010323_32 peptidyl-tyrosine sulfation - - - 0.0002179 51.0
HFD2_k127_4010323_4 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 550.0
HFD2_k127_4010323_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008874 418.0
HFD2_k127_4010323_6 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 419.0
HFD2_k127_4010323_7 phosphorelay signal transduction system K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 397.0
HFD2_k127_4010323_8 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 363.0
HFD2_k127_4010323_9 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 319.0
HFD2_k127_4044206_0 LVIVD repeat - - - 2.639e-266 833.0
HFD2_k127_4044206_1 PFAM aldehyde oxidase and xanthine dehydrogenase molybdopterin binding K00256 - 1.3.99.16 2.707e-238 758.0
HFD2_k127_4044206_10 retrograde transport, endosome to Golgi K07095 - - 0.00008779 49.0
HFD2_k127_4044206_2 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008718 343.0
HFD2_k127_4044206_3 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002454 267.0
HFD2_k127_4044206_4 2Fe-2S -binding domain protein K18029 - 1.17.2.1 0.000000000000000000000000000000000000000000000000000000000006184 212.0
HFD2_k127_4044206_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000002119 212.0
HFD2_k127_4044206_6 Domain of unknown function (DUF305) - - - 0.00000000000000000000000000000000000000000000000000006878 209.0
HFD2_k127_4044206_7 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000002871 172.0
HFD2_k127_4044206_8 ORF6N domain - - - 0.00000000000000000000000000000000000000006661 162.0
HFD2_k127_4052512_0 Iron permease FTR1 K07243 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001362 276.0
HFD2_k127_4052512_1 Zn_pept - - - 0.0000000000000000000000000000000000000000000000000000000000000341 244.0
HFD2_k127_4052512_2 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000002802 201.0
HFD2_k127_4052512_3 PFAM regulatory protein TetR - - - 0.000000000000000000000001644 112.0
HFD2_k127_4052512_4 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000003315 106.0
HFD2_k127_4052512_6 outer membrane efflux protein - - - 0.00000000000001929 87.0
HFD2_k127_4077052_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 534.0
HFD2_k127_4077052_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 450.0
HFD2_k127_4077052_2 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 410.0
HFD2_k127_4077052_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000004271 232.0
HFD2_k127_4077052_4 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000001154 193.0
HFD2_k127_4077052_5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K21681 - 1.1.1.405,2.7.7.40,2.7.7.60 0.00000000000000000000000000000000000000000005539 172.0
HFD2_k127_4077052_6 shikimate 3-dehydrogenase (NADP+) activity K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000005472 154.0
HFD2_k127_4077052_7 Low molecular weight phosphatase family K01104 - 3.1.3.48 0.00000000000000000000000000000000004351 146.0
HFD2_k127_4077052_8 Phosphoribosyl transferase domain - - - 0.00000000000000000000000504 117.0
HFD2_k127_4077052_9 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000006836 74.0
HFD2_k127_4106834_0 peptidase S9B dipeptidylpeptidase IV domain protein - - - 3.316e-314 979.0
HFD2_k127_4106834_1 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 606.0
HFD2_k127_4106834_10 4Fe-4S binding domain K08358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 308.0
HFD2_k127_4106834_11 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K04013,K15876 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003518 249.0
HFD2_k127_4106834_12 tRNA processing K06864 - - 0.0000000000000000000000000000000000000000000000000000000000007892 241.0
HFD2_k127_4106834_13 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000001674 212.0
HFD2_k127_4106834_14 peptide catabolic process - - - 0.000000000000000000000000000000000000000000000000000002113 214.0
HFD2_k127_4106834_15 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000002397 190.0
HFD2_k127_4106834_16 - - - - 0.000000000000000000000000000000000000000000001307 186.0
HFD2_k127_4106834_17 DinB family - - - 0.000000000000000000000000000000000000000000003863 171.0
HFD2_k127_4106834_18 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000003735 174.0
HFD2_k127_4106834_19 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.000000000000000000000000000000000004008 143.0
HFD2_k127_4106834_2 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005047 584.0
HFD2_k127_4106834_20 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000141 134.0
HFD2_k127_4106834_21 nuclease activity - - - 0.0000000000000000000000000000003496 129.0
HFD2_k127_4106834_22 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000001532 138.0
HFD2_k127_4106834_23 - - - - 0.0000000000000000000000002916 112.0
HFD2_k127_4106834_24 Adenylate cyclase K01768 - 4.6.1.1 0.0000000000000000006021 89.0
HFD2_k127_4106834_25 thiolester hydrolase activity - - - 0.00000000000000002818 93.0
HFD2_k127_4106834_26 Bacterial antitoxin of type II TA system, VapB - - - 0.00000000000001888 76.0
HFD2_k127_4106834_28 - - - - 0.0000006667 63.0
HFD2_k127_4106834_29 - - - - 0.0002104 51.0
HFD2_k127_4106834_3 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 523.0
HFD2_k127_4106834_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 494.0
HFD2_k127_4106834_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 460.0
HFD2_k127_4106834_6 glyoxalase bleomycin resistance protein dioxygenase K15975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 407.0
HFD2_k127_4106834_7 CHASE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 344.0
HFD2_k127_4106834_8 Homoserine dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 323.0
HFD2_k127_4106834_9 Domain of unknown function (DUF4162) K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 304.0
HFD2_k127_41191_0 PFAM Glycoside hydrolase, family 20 K12373 - 3.2.1.52 1.095e-214 687.0
HFD2_k127_41191_1 Sodium:solute symporter family - - - 7.176e-198 627.0
HFD2_k127_41191_10 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000001741 156.0
HFD2_k127_41191_11 heme-binding sites - - - 0.000000000000000000000009651 112.0
HFD2_k127_41191_12 Fibronectin type 3 domain K20276 - - 0.00000000000000000006263 106.0
HFD2_k127_41191_13 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000006555 66.0
HFD2_k127_41191_14 6-phosphogluconolactonase activity - - - 0.000000009084 68.0
HFD2_k127_41191_15 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000006174 66.0
HFD2_k127_41191_16 - - - - 0.0000005322 63.0
HFD2_k127_41191_2 Belongs to the peptidase S1B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 576.0
HFD2_k127_41191_3 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 447.0
HFD2_k127_41191_4 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005644 284.0
HFD2_k127_41191_5 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002904 284.0
HFD2_k127_41191_6 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000009326 243.0
HFD2_k127_41191_7 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000009424 232.0
HFD2_k127_41191_8 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000002318 236.0
HFD2_k127_41191_9 - - - - 0.0000000000000000000000000000000000000007049 157.0
HFD2_k127_4120907_0 PFAM glycosyl hydrolase BNR repeat-containing protein - - - 0.0 1176.0
HFD2_k127_4120907_1 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00819,K00821 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.11,2.6.1.13,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004702 539.0
HFD2_k127_4120907_10 PFAM PKD domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001259 275.0
HFD2_k127_4120907_11 AMP-binding enzyme K01911 - 6.2.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000003589 263.0
HFD2_k127_4120907_12 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000003171 218.0
HFD2_k127_4120907_13 Biotin carboxylase - - - 0.000000000000000000000000000000000000000000000000000000002829 229.0
HFD2_k127_4120907_14 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000002143 208.0
HFD2_k127_4120907_15 ATP-independent chaperone mediated protein folding - - - 0.0000000000000000000000000000000000004809 146.0
HFD2_k127_4120907_16 D-aminopeptidase K16203 - - 0.000000000000000000000000000000027 138.0
HFD2_k127_4120907_17 Scaffold protein Nfu/NifU N terminal - - - 0.00000000000000000000000001408 121.0
HFD2_k127_4120907_18 nuclear chromosome segregation - - - 0.00000000000000000000000008654 119.0
HFD2_k127_4120907_19 Dodecin K09165 - - 0.0000000000000000000001039 99.0
HFD2_k127_4120907_2 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 522.0
HFD2_k127_4120907_20 Response regulator, receiver - - - 0.000000000000000000259 92.0
HFD2_k127_4120907_21 WD40 domain protein beta Propeller K03641 - - 0.000000000000000001042 102.0
HFD2_k127_4120907_3 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 513.0
HFD2_k127_4120907_4 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 528.0
HFD2_k127_4120907_5 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 461.0
HFD2_k127_4120907_6 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 327.0
HFD2_k127_4120907_7 succinylglutamate desuccinylase aspartoacylase K06987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 327.0
HFD2_k127_4120907_8 D-aminopeptidase K16203 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 309.0
HFD2_k127_4120907_9 D-ala-D-ala dipeptidase K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008149 291.0
HFD2_k127_4175758_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 617.0
HFD2_k127_4175758_1 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005623 606.0
HFD2_k127_4175758_2 PFAM iron dependent repressor K03709 - - 0.000000000002407 74.0
HFD2_k127_4183184_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.791e-241 762.0
HFD2_k127_4183184_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 3.489e-222 723.0
HFD2_k127_4183184_10 Glycosyl transferases group 1 K19424 - - 0.000000000000000000000003103 109.0
HFD2_k127_4183184_11 polysaccharide export - - - 0.0000000000000000000000294 111.0
HFD2_k127_4183184_12 response regulator receiver K03413 - - 0.00000000000000000000003355 111.0
HFD2_k127_4183184_13 Bacterial Ig-like domain 2 - - - 0.00000004758 60.0
HFD2_k127_4183184_2 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 605.0
HFD2_k127_4183184_3 Chain length determinant protein K16554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 542.0
HFD2_k127_4183184_4 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 405.0
HFD2_k127_4183184_5 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009372 299.0
HFD2_k127_4183184_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001303 261.0
HFD2_k127_4183184_7 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006254 250.0
HFD2_k127_4183184_8 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000001329 229.0
HFD2_k127_4183184_9 Protein of unknown function (DUF3485) - - - 0.0000000000000000000000000000000000000000000000000003566 198.0
HFD2_k127_4202051_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004044 422.0
HFD2_k127_4202051_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 398.0
HFD2_k127_4202051_2 Secretion protein K01993 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000001358 190.0
HFD2_k127_420234_0 oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor K00311 GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204 1.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 629.0
HFD2_k127_420234_1 Electron transfer flavoprotein domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 298.0
HFD2_k127_420234_2 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005932 281.0
HFD2_k127_420234_3 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005147 274.0
HFD2_k127_420234_4 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000009874 226.0
HFD2_k127_4209527_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1275.0
HFD2_k127_4209527_1 Thymidine kinase K00857 - 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 293.0
HFD2_k127_4209527_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007498 295.0
HFD2_k127_4209527_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000006648 226.0
HFD2_k127_4209527_4 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000004157 205.0
HFD2_k127_4209527_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000007438 172.0
HFD2_k127_4209527_6 Biotin/lipoate A/B protein ligase family K03800 - 6.3.1.20 0.000000000000000000000000000000000000000001096 169.0
HFD2_k127_4209527_7 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000343 106.0
HFD2_k127_4209527_8 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000002627 67.0
HFD2_k127_4236724_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 5.458e-284 881.0
HFD2_k127_4236724_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K15856 - 1.1.1.281 0.00000000000000000000000000000000000000001365 162.0
HFD2_k127_4243793_0 Carbohydrate family 9 binding domain-like - - - 2.77e-301 947.0
HFD2_k127_4243793_1 Peptidase dimerisation domain K12941 - - 5.204e-203 669.0
HFD2_k127_4243793_10 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000003462 147.0
HFD2_k127_4243793_11 GyrI-like small molecule binding domain - - - 0.0000000000000000000000000000006304 129.0
HFD2_k127_4243793_12 Endonuclease related to archaeal Holliday junction resolvase - - - 0.000000000000000000000000002568 118.0
HFD2_k127_4243793_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000002103 116.0
HFD2_k127_4243793_14 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000001342 97.0
HFD2_k127_4243793_15 Helix-turn-helix XRE-family like proteins - - - 0.00000000000001518 85.0
HFD2_k127_4243793_16 EamA-like transporter family - - - 0.00000000000005506 86.0
HFD2_k127_4243793_17 Redoxin - - - 0.00000002132 58.0
HFD2_k127_4243793_19 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00002775 53.0
HFD2_k127_4243793_2 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008142 461.0
HFD2_k127_4243793_20 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000532 49.0
HFD2_k127_4243793_21 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.0007284 46.0
HFD2_k127_4243793_3 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 401.0
HFD2_k127_4243793_4 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 398.0
HFD2_k127_4243793_5 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 398.0
HFD2_k127_4243793_6 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000002181 246.0
HFD2_k127_4243793_7 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000001802 218.0
HFD2_k127_4243793_8 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000006115 192.0
HFD2_k127_4243793_9 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000001639 186.0
HFD2_k127_4273575_0 Protein of unknown function (DUF512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 476.0
HFD2_k127_4273575_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 394.0
HFD2_k127_4273575_2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007572 351.0
HFD2_k127_4273575_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 303.0
HFD2_k127_4273575_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000001749 235.0
HFD2_k127_4273575_5 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000436 171.0
HFD2_k127_4273575_6 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000267 170.0
HFD2_k127_4273575_7 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000001121 158.0
HFD2_k127_4273575_8 Acylphosphatase K01512 - 3.6.1.7 0.00000000000002858 83.0
HFD2_k127_4273575_9 Tetratricopeptide repeat-like domain - - - 0.000000006555 66.0
HFD2_k127_4318913_0 FGGY family of carbohydrate kinases, C-terminal domain K00853 - 2.7.1.16 3.048e-232 730.0
HFD2_k127_4318913_1 symporter activity K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 526.0
HFD2_k127_4318913_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 449.0
HFD2_k127_4318913_3 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source K03077 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004732 278.0
HFD2_k127_4318913_4 isomerase activity K01805 - 5.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000009705 253.0
HFD2_k127_432187_0 Prokaryotic cytochrome b561 - - - 1.5e-323 1013.0
HFD2_k127_432187_1 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 2.119e-243 769.0
HFD2_k127_432187_10 DsrE/DsrF-like family K06039 - - 0.0000000000000000000000000000000001984 139.0
HFD2_k127_432187_11 subunit of a heme lyase K02200 - - 0.0000000000000000000000000002791 126.0
HFD2_k127_432187_12 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000002107 120.0
HFD2_k127_432187_13 - - - - 0.000000000000005313 87.0
HFD2_k127_432187_2 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 7.721e-197 627.0
HFD2_k127_432187_3 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 451.0
HFD2_k127_432187_4 ATP ADP translocase K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 437.0
HFD2_k127_432187_5 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 347.0
HFD2_k127_432187_6 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004059 289.0
HFD2_k127_432187_7 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000008305 189.0
HFD2_k127_432187_8 Cytochrome c K00413 - - 0.00000000000000000000000000000000000000000000001137 188.0
HFD2_k127_432187_9 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.000000000000000000000000000000000000001347 167.0
HFD2_k127_4344879_0 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 7.137e-311 966.0
HFD2_k127_4344879_1 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 532.0
HFD2_k127_4344879_10 BON domain - - - 0.0000000001271 67.0
HFD2_k127_4344879_2 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 367.0
HFD2_k127_4344879_3 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 360.0
HFD2_k127_4344879_4 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.000000000000000000000000000000000000000000000000000000004158 220.0
HFD2_k127_4344879_5 MOSC domain - - - 0.000000000000000000000000000000000000000000000006666 184.0
HFD2_k127_4344879_6 - - - - 0.000000000000000000000000000000000000000001211 160.0
HFD2_k127_4344879_7 PFAM cobalamin (vitamin B12) biosynthesis CbiM K02007 - - 0.00000000000000000000000000000000000000003725 162.0
HFD2_k127_4344879_8 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.0000000000000000000004824 111.0
HFD2_k127_4344879_9 iron-sulfur cluster biosynthesis transcriptional regulator SufR K09012 - - 0.00000000000005654 80.0
HFD2_k127_4348275_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002191 256.0
HFD2_k127_4348275_1 Alpha beta hydrolase - - - 0.000000000000000001245 95.0
HFD2_k127_4348275_2 WHG domain - - - 0.00000000000002776 77.0
HFD2_k127_4372275_0 Alpha-L-fucosidase K01206 - 3.2.1.51 1.264e-205 649.0
HFD2_k127_4372275_1 PFAM binding-protein-dependent transport systems inner membrane component K02025,K17242 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001208 290.0
HFD2_k127_4372275_2 PFAM Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006889 265.0
HFD2_k127_4372275_3 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.00000000000000000000000000000000000000000000000000000007635 205.0
HFD2_k127_4372275_4 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.0000000000000000000000000000000000000000000000000002324 195.0
HFD2_k127_4372275_5 Histidine kinase - - - 0.0000000000000000000000000000000003127 152.0
HFD2_k127_4420908_0 Amidohydrolase family K06015 - 3.5.1.81 5.436e-249 780.0
HFD2_k127_4420908_1 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 2.376e-224 711.0
HFD2_k127_4420908_10 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000008573 190.0
HFD2_k127_4420908_11 PFAM S23 ribosomal protein - - - 0.000004589 57.0
HFD2_k127_4420908_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006859 606.0
HFD2_k127_4420908_3 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 465.0
HFD2_k127_4420908_4 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001778 299.0
HFD2_k127_4420908_5 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000007012 230.0
HFD2_k127_4420908_6 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000007066 247.0
HFD2_k127_4420908_7 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000001077 220.0
HFD2_k127_4420908_8 Bacterial transcriptional activator domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000149 209.0
HFD2_k127_4420908_9 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000003351 190.0
HFD2_k127_4421215_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 577.0
HFD2_k127_4421215_1 PFAM Late competence development protein ComFB K02241 - - 0.0000000003111 72.0
HFD2_k127_4421215_2 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.000005539 52.0
HFD2_k127_4430694_0 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008719 279.0
HFD2_k127_4430694_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001627 277.0
HFD2_k127_4430694_2 homoserine transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000003934 205.0
HFD2_k127_4433842_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005985 519.0
HFD2_k127_4433842_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 426.0
HFD2_k127_4433842_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 373.0
HFD2_k127_4433842_3 Uncharacterised protein family UPF0102 K07460 - - 0.00000000000000000000000000000002661 135.0
HFD2_k127_4433842_4 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000002765 75.0
HFD2_k127_4433842_6 Protein of unknown function (DUF1416) - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0004452 51.0
HFD2_k127_4498052_0 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 526.0
HFD2_k127_4498052_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 390.0
HFD2_k127_4498052_2 phenylacetic acid catabolic K02609 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 383.0
HFD2_k127_4498052_3 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000003969 152.0
HFD2_k127_4498052_4 PFAM Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000002925 128.0
HFD2_k127_4498052_5 Pfam:DUF59 K02612 - - 0.00000000000000000000000002979 111.0
HFD2_k127_4498052_6 PFAM phenylacetic acid catabolic family protein K02611 - 1.14.13.149 0.00000000000000000004366 103.0
HFD2_k127_4498052_7 Phenylacetic acid degradation B - - - 0.000000000000002537 82.0
HFD2_k127_4498052_8 Phenylacetate-CoA oxygenase K02612 - - 0.000003388 55.0
HFD2_k127_4502309_0 Domain of unknown function (DUF4277) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 590.0
HFD2_k127_4502309_1 Domain of unknown function (DUF4277) - - - 0.00000000000000000000000000000000000000002079 156.0
HFD2_k127_4517652_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0 1498.0
HFD2_k127_4517652_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 604.0
HFD2_k127_4517652_10 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000000000000000001062 236.0
HFD2_k127_4517652_11 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000009218 214.0
HFD2_k127_4517652_12 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000001037 185.0
HFD2_k127_4517652_13 Seven times multi-haem cytochrome CxxCH K10535 - 1.7.2.6 0.00000000000000000000000000000000000000000000000004521 199.0
HFD2_k127_4517652_14 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000002037 177.0
HFD2_k127_4517652_15 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000708 144.0
HFD2_k127_4517652_16 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000004088 90.0
HFD2_k127_4517652_17 Rhodanese Homology Domain - - - 0.0000000003263 73.0
HFD2_k127_4517652_18 Hemerythrin HHE cation binding domain - - - 0.00000000761 63.0
HFD2_k127_4517652_19 Cytochrome c - - - 0.0001011 55.0
HFD2_k127_4517652_2 Sulfate permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 489.0
HFD2_k127_4517652_3 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 494.0
HFD2_k127_4517652_4 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 461.0
HFD2_k127_4517652_5 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 419.0
HFD2_k127_4517652_6 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006787 396.0
HFD2_k127_4517652_7 Alanine dehydrogenase/PNT, C-terminal domain K07538 - 1.1.1.368 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 357.0
HFD2_k127_4517652_8 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 308.0
HFD2_k127_4517652_9 Enoyl-(Acyl carrier protein) reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000001301 237.0
HFD2_k127_4522647_0 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 381.0
HFD2_k127_4536749_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 4.119e-296 930.0
HFD2_k127_4536749_1 lysine biosynthetic process via aminoadipic acid - - - 1.798e-203 659.0
HFD2_k127_4536749_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 468.0
HFD2_k127_4536749_3 Membrane dipeptidase (Peptidase family M19) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 445.0
HFD2_k127_4536749_4 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000001576 228.0
HFD2_k127_4536749_5 homoserine kinase activity K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.0000000000000000000000000000000000000000000002128 181.0
HFD2_k127_4536749_6 TIGRFAM endoribonuclease L-PSP - - - 0.000000000000000000000000000000001979 135.0
HFD2_k127_4536749_7 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000008479 89.0
HFD2_k127_4536749_8 - - - - 0.0000000000000002991 83.0
HFD2_k127_4536749_9 Protein of unknown function (DUF1569) - - - 0.00000000002772 75.0
HFD2_k127_455956_0 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 487.0
HFD2_k127_455956_1 Bacterial extracellular solute-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 407.0
HFD2_k127_455956_2 TIGRFAM sulfate ABC transporter K02046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 351.0
HFD2_k127_455956_3 sulfate ABC transporter K02047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 301.0
HFD2_k127_455956_4 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.000000000000000000000000000000000009177 153.0
HFD2_k127_455956_5 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000000000000000000000000000007011 136.0
HFD2_k127_4561135_0 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007771 382.0
HFD2_k127_4573092_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1138.0
HFD2_k127_4573092_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 597.0
HFD2_k127_4573092_10 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000202 176.0
HFD2_k127_4573092_11 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000006478 175.0
HFD2_k127_4573092_12 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000000000000000000000000000001317 157.0
HFD2_k127_4573092_13 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000008905 157.0
HFD2_k127_4573092_14 protein secretion K21449 - - 0.00000000000000000000000001196 113.0
HFD2_k127_4573092_16 Membrane - - - 0.000002901 60.0
HFD2_k127_4573092_17 CAAX protease self-immunity K07052 - - 0.00008661 49.0
HFD2_k127_4573092_2 cobalamin-transporting ATPase activity K02014,K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 504.0
HFD2_k127_4573092_3 Elongation factor SelB winged helix 3 K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 413.0
HFD2_k127_4573092_4 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667,K01668 - 4.1.99.1,4.1.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001747 259.0
HFD2_k127_4573092_5 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007865 250.0
HFD2_k127_4573092_6 FecCD transport family K02013,K02015 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000001475 251.0
HFD2_k127_4573092_7 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000001266 211.0
HFD2_k127_4573092_8 Iron-storage protein K02217 - 1.16.3.2 0.000000000000000000000000000000000000000000000001827 180.0
HFD2_k127_4573092_9 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.0000000000000000000000000000000000000000000001043 175.0
HFD2_k127_457501_0 oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor K00311 GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204 1.5.5.1 5.758e-205 668.0
HFD2_k127_457501_1 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 573.0
HFD2_k127_457501_2 Electron transfer flavoprotein domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 404.0
HFD2_k127_457501_3 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 291.0
HFD2_k127_457501_4 PFAM Abortive infection protein K07052 - - 0.00000000000000000000008501 113.0
HFD2_k127_457501_5 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000006232 97.0
HFD2_k127_457501_6 Bacterial Ig-like domain 2 - - - 0.00000000000001203 87.0
HFD2_k127_457501_7 Prokaryotic N-terminal methylation motif - - - 0.0000004235 57.0
HFD2_k127_457550_0 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K17763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 441.0
HFD2_k127_457550_1 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 376.0
HFD2_k127_457550_2 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 344.0
HFD2_k127_457550_3 ggdef domain - - - 0.000000000000000000000000000000000000000000000002156 188.0
HFD2_k127_457550_4 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000003357 176.0
HFD2_k127_457550_5 STAS domain K17762 - - 0.0000000000000000000000000000000000000000001208 162.0
HFD2_k127_457550_6 Histidine kinase-like ATPase domain K17752 - 2.7.11.1 0.000000000000000000000000006787 115.0
HFD2_k127_457550_7 self proteolysis - - - 0.00000003414 64.0
HFD2_k127_457550_8 DNA-binding transcriptional activator of the SARP family - - - 0.00007611 56.0
HFD2_k127_4592449_0 iron-nicotianamine transmembrane transporter activity - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 1.353e-292 919.0
HFD2_k127_4592449_1 TIGRFAM aminoacyl-histidine dipeptidase K01270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 567.0
HFD2_k127_4592449_10 Protein of unknown function (DUF2384) - - - 0.000000000000000000003198 104.0
HFD2_k127_4592449_11 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000002814 95.0
HFD2_k127_4592449_12 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000549 65.0
HFD2_k127_4592449_2 M42 glutamyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 423.0
HFD2_k127_4592449_3 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000018 297.0
HFD2_k127_4592449_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000001051 172.0
HFD2_k127_4592449_5 HEAT repeats - - - 0.00000000000000000000000000000000000000006515 170.0
HFD2_k127_4592449_6 HEAT repeats - - - 0.0000000000000000000000000000000000000002249 168.0
HFD2_k127_4592449_7 RES - - - 0.000000000000000000000000000001056 130.0
HFD2_k127_4592449_8 PFAM PIN domain - - - 0.000000000000000000000000000007203 127.0
HFD2_k127_4592449_9 pfam gaf K08968 - 1.8.4.14 0.0000000000000000000000002247 111.0
HFD2_k127_4649786_0 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 561.0
HFD2_k127_4649786_1 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 460.0
HFD2_k127_4649786_10 peptidase activity - - - 0.000695 46.0
HFD2_k127_4649786_2 amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 449.0
HFD2_k127_4649786_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 322.0
HFD2_k127_4649786_4 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001066 284.0
HFD2_k127_4649786_5 Putative lumazine-binding - - - 0.000000000000000000000000000000000000000000007607 167.0
HFD2_k127_4649786_6 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000002714 175.0
HFD2_k127_4649786_7 - - - - 0.00000000000000000000000000000115 125.0
HFD2_k127_4649786_8 oligoendopeptidase F K08602 - - 0.00000000000000001216 98.0
HFD2_k127_4649786_9 ubiE/COQ5 methyltransferase family - - - 0.00000000000000002669 91.0
HFD2_k127_4682262_0 membrane organization - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 460.0
HFD2_k127_4682262_1 SdiA-regulated - - - 0.00000000000000000000000000005588 132.0
HFD2_k127_4682262_2 Domain of unknown function (DUF4956) - - - 0.0000000000000000000000000003143 127.0
HFD2_k127_4695051_0 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 2.432e-295 955.0
HFD2_k127_4695051_1 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 1.078e-213 674.0
HFD2_k127_4695051_10 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 317.0
HFD2_k127_4695051_11 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005676 297.0
HFD2_k127_4695051_12 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009729 260.0
HFD2_k127_4695051_13 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000005488 220.0
HFD2_k127_4695051_14 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000233 196.0
HFD2_k127_4695051_15 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000005773 181.0
HFD2_k127_4695051_16 FAD linked oxidases, C-terminal domain K11472 - - 0.000000000000000000000000000000000000001038 166.0
HFD2_k127_4695051_17 Psort location Cytoplasmic, score K00945 - 2.7.4.25 0.000000000000000000000000000000000001171 147.0
HFD2_k127_4695051_18 YGGT family K02221 - - 0.00000000000000000000000000000000001302 142.0
HFD2_k127_4695051_19 Glycine cleavage T-protein C-terminal barrel domain K06980 - - 0.000000000000000000000000000000000979 147.0
HFD2_k127_4695051_2 von Willebrand factor (vWF) type A domain - - - 9.682e-195 616.0
HFD2_k127_4695051_20 ATP-dependent protease La (LON) substrate-binding domain K01338 - 3.4.21.53 0.0000000000000000000000000000001576 133.0
HFD2_k127_4695051_21 - - - - 0.0000000000000000000000000007509 119.0
HFD2_k127_4695051_22 - - - - 0.0000000005179 67.0
HFD2_k127_4695051_23 Protein tyrosine kinase K12132 - 2.7.11.1 0.0005145 53.0
HFD2_k127_4695051_3 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 577.0
HFD2_k127_4695051_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009835 451.0
HFD2_k127_4695051_5 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 415.0
HFD2_k127_4695051_6 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004552 399.0
HFD2_k127_4695051_7 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 375.0
HFD2_k127_4695051_8 4Fe-4S binding domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 365.0
HFD2_k127_4695051_9 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 333.0
HFD2_k127_4699091_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 5.652e-309 970.0
HFD2_k127_4699091_1 Amidohydrolase family - - - 2.462e-307 977.0
HFD2_k127_4699091_10 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001942 261.0
HFD2_k127_4699091_11 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000002519 261.0
HFD2_k127_4699091_12 Roadblock/LC7 domain - - - 0.0000000000000000000000000000000000000000000000000000000961 199.0
HFD2_k127_4699091_13 PFAM aminotransferase class V K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000002379 201.0
HFD2_k127_4699091_14 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000007 179.0
HFD2_k127_4699091_15 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000005296 147.0
HFD2_k127_4699091_16 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000003489 110.0
HFD2_k127_4699091_17 PFAM Membrane protein of K08972 - - 0.0000000000000000000001613 101.0
HFD2_k127_4699091_18 - - - - 0.000000000000000536 83.0
HFD2_k127_4699091_2 Prolyl oligopeptidase family - - - 3.061e-238 761.0
HFD2_k127_4699091_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009981 619.0
HFD2_k127_4699091_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 477.0
HFD2_k127_4699091_5 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 472.0
HFD2_k127_4699091_6 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 458.0
HFD2_k127_4699091_7 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009663 396.0
HFD2_k127_4699091_8 Competence-damaged protein K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 395.0
HFD2_k127_4699091_9 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 380.0
HFD2_k127_470590_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 9.987e-318 989.0
HFD2_k127_470590_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.047e-248 792.0
HFD2_k127_470590_10 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009218 406.0
HFD2_k127_470590_11 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 362.0
HFD2_k127_470590_12 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 368.0
HFD2_k127_470590_13 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 365.0
HFD2_k127_470590_14 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 367.0
HFD2_k127_470590_15 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005047 332.0
HFD2_k127_470590_16 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 291.0
HFD2_k127_470590_17 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000001368 272.0
HFD2_k127_470590_18 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000008042 248.0
HFD2_k127_470590_19 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000005529 252.0
HFD2_k127_470590_2 Enoyl-CoA hydratase/isomerase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 4.976e-212 681.0
HFD2_k127_470590_20 Belongs to the GTP cyclohydrolase I type 2 NIF3 family K22391 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000002215 234.0
HFD2_k127_470590_21 Belongs to the ParB family K03497 GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000007188 231.0
HFD2_k127_470590_22 Domain of unknown function (DUF1835) - - - 0.0000000000000000000000000000000000000000000000000000000000007049 223.0
HFD2_k127_470590_23 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000004214 220.0
HFD2_k127_470590_24 NifU-like N terminal domain K04488 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000007817 197.0
HFD2_k127_470590_25 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000004141 217.0
HFD2_k127_470590_26 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000001399 168.0
HFD2_k127_470590_27 Bacterial capsule synthesis protein PGA_cap - - - 0.0000000000000000000000000000000000000001821 169.0
HFD2_k127_470590_28 tRNA-binding protein K06878 - - 0.000000000000000000000000000000000000005192 153.0
HFD2_k127_470590_29 - - - - 0.00000000000000000000000000000004322 129.0
HFD2_k127_470590_3 Beta-eliminating lyase K01667 - 4.1.99.1 2.309e-208 668.0
HFD2_k127_470590_30 PFAM Peptidase family M23 - - - 0.0000000000000000000000005411 121.0
HFD2_k127_470590_31 Tellurite resistance protein TehB - - - 0.0000000000000000000005896 105.0
HFD2_k127_470590_32 - - - - 0.0000000000003481 78.0
HFD2_k127_470590_33 - - - - 0.000000003855 68.0
HFD2_k127_470590_34 Polymer-forming cytoskeletal - - - 0.000005036 56.0
HFD2_k127_470590_4 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 595.0
HFD2_k127_470590_5 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 554.0
HFD2_k127_470590_6 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008141 547.0
HFD2_k127_470590_7 Uncharacterized protein family (UPF0051) K09014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 512.0
HFD2_k127_470590_8 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 505.0
HFD2_k127_470590_9 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 490.0
HFD2_k127_4712225_0 E1-E2 ATPase K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 341.0
HFD2_k127_4712225_1 transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000009668 178.0
HFD2_k127_4712225_2 negative regulation of transcription, DNA-templated K21600 - - 0.00000000000000000000000000000004576 129.0
HFD2_k127_4743100_0 COG0367 Asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 8.026e-200 642.0
HFD2_k127_4743100_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 414.0
HFD2_k127_4743100_10 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000002348 185.0
HFD2_k127_4743100_11 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000005988 151.0
HFD2_k127_4743100_12 O-Antigen ligase - - - 0.00000000000000000000000000006952 132.0
HFD2_k127_4743100_13 - - - - 0.00000000000000003065 95.0
HFD2_k127_4743100_14 Polysaccharide deacetylase - - - 0.000000002122 69.0
HFD2_k127_4743100_15 Bacterial Ig-like domain 2 K01176 - 3.2.1.1 0.00006061 55.0
HFD2_k127_4743100_2 Nucleotidyl transferase K00978 - 2.7.7.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008237 369.0
HFD2_k127_4743100_3 Polysaccharide biosynthesis protein K03328 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 351.0
HFD2_k127_4743100_4 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 349.0
HFD2_k127_4743100_5 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 305.0
HFD2_k127_4743100_6 Glycosyl transferases group 1 K21001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003812 290.0
HFD2_k127_4743100_7 Transport permease protein K09688,K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001238 261.0
HFD2_k127_4743100_8 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000001126 239.0
HFD2_k127_4743100_9 lipopolysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000003288 197.0
HFD2_k127_4762632_0 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 623.0
HFD2_k127_4762632_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000684 218.0
HFD2_k127_4762632_2 efflux transmembrane transporter activity - - - 0.0000000000000005725 87.0
HFD2_k127_4790353_0 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009703 280.0
HFD2_k127_4790353_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001162 293.0
HFD2_k127_4790353_2 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005367 260.0
HFD2_k127_479597_0 COG0433 Predicted ATPase K06915 - - 1.072e-242 768.0
HFD2_k127_479597_1 AAA domain K03546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 551.0
HFD2_k127_479597_10 - - - - 0.00000000000000000000001721 110.0
HFD2_k127_479597_11 domain, Protein K13735 - - 0.0000000000008039 82.0
HFD2_k127_479597_12 cellulose binding - - - 0.000000001601 71.0
HFD2_k127_479597_13 Membrane proteins related to metalloendopeptidases K06194 - - 0.000000002792 70.0
HFD2_k127_479597_2 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 432.0
HFD2_k127_479597_3 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 385.0
HFD2_k127_479597_4 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 347.0
HFD2_k127_479597_5 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 302.0
HFD2_k127_479597_6 GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000006038 267.0
HFD2_k127_479597_7 KR domain - - - 0.00000000000000000000000000000000000000000000000000000009967 213.0
HFD2_k127_479597_8 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000000000000006603 142.0
HFD2_k127_479597_9 COGs COG2380 conserved K09785 - - 0.000000000000000000000005582 113.0
HFD2_k127_4796593_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 636.0
HFD2_k127_4796593_1 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs K00375 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007628 509.0
HFD2_k127_4796593_10 Peptidase M56, BlaR1 - - - 0.000000000000000000000000000000000000000000000000000009814 199.0
HFD2_k127_4796593_11 Sel1-like repeats. K07126 - - 0.00000000000000000000000000000000000000000000000000009692 199.0
HFD2_k127_4796593_12 - - - - 0.0000000000000000000000000000000000000000000114 168.0
HFD2_k127_4796593_13 Penicillinase repressor - - - 0.00000000000000000000000000000000001072 140.0
HFD2_k127_4796593_14 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.0000000000000000000000000000006898 140.0
HFD2_k127_4796593_15 proteolysis K19225 - 3.4.21.105 0.00000000000000000000000000005106 125.0
HFD2_k127_4796593_16 ABC-2 family transporter protein K01992 - - 0.000000000000000000000001894 111.0
HFD2_k127_4796593_17 - - - - 0.000000002389 71.0
HFD2_k127_4796593_2 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 492.0
HFD2_k127_4796593_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 477.0
HFD2_k127_4796593_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005666 408.0
HFD2_k127_4796593_5 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009599 404.0
HFD2_k127_4796593_6 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 383.0
HFD2_k127_4796593_7 abc transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 329.0
HFD2_k127_4796593_8 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005674 311.0
HFD2_k127_4796593_9 - - - - 0.00000000000000000000000000000000000000000000000000000000001005 214.0
HFD2_k127_4832862_0 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 359.0
HFD2_k127_4832862_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 312.0
HFD2_k127_4832862_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002265 261.0
HFD2_k127_4832862_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001534 264.0
HFD2_k127_4832862_4 Biotin/lipoate A/B protein ligase family K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.00004328 51.0
HFD2_k127_4900460_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 353.0
HFD2_k127_4900460_1 HmuY protein - - - 0.00000000000000003435 89.0
HFD2_k127_4924288_0 tRNA synthetases class I (M) K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 535.0
HFD2_k127_4924288_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 409.0
HFD2_k127_4924288_2 PSP1 C-terminal conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 334.0
HFD2_k127_4924288_3 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000001965 168.0
HFD2_k127_4927424_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004703 450.0
HFD2_k127_4927424_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000914 428.0
HFD2_k127_4927424_2 Tetratricopeptide repeat - - - 0.0000000002923 71.0
HFD2_k127_4992526_0 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 304.0
HFD2_k127_4992526_1 TonB C terminal K03832 - - 0.00000000000000000000000000000000002231 144.0
HFD2_k127_4992526_2 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.00000000000000000001438 93.0
HFD2_k127_501903_0 DEAD DEAH box helicase K03724 - - 0.0 1653.0
HFD2_k127_501903_1 - - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259 - 0.0 1103.0
HFD2_k127_501903_10 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 315.0
HFD2_k127_501903_11 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000001226 239.0
HFD2_k127_501903_12 Peptidase M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000001321 235.0
HFD2_k127_501903_13 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000001833 241.0
HFD2_k127_501903_14 PAS domain - - - 0.0000000000000000000000000000000000000003808 170.0
HFD2_k127_501903_15 Cytochrome c - - - 0.00000000000000000000001827 104.0
HFD2_k127_501903_16 TIGRFAM competence protein ComEA helix-hairpin-helix repeat K02237 - - 0.00000000000000001611 91.0
HFD2_k127_501903_2 PQQ-like domain K00117 - 1.1.5.2 2.578e-215 689.0
HFD2_k127_501903_3 General secretory system II protein E domain protein K02652 - - 1.027e-195 626.0
HFD2_k127_501903_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005736 603.0
HFD2_k127_501903_5 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000837 580.0
HFD2_k127_501903_6 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 558.0
HFD2_k127_501903_7 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 407.0
HFD2_k127_501903_8 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 336.0
HFD2_k127_501903_9 Predicted permease YjgP/YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 313.0
HFD2_k127_5045035_0 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 398.0
HFD2_k127_5045035_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000006773 210.0
HFD2_k127_5045035_2 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000006578 125.0
HFD2_k127_5045035_3 Leucine rich repeats (6 copies) - - - 0.000005069 60.0
HFD2_k127_5084631_0 Glycosyl hydrolases family 2, TIM barrel domain K01190,K01195 GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005575,GO:0005975,GO:0005984,GO:0005988,GO:0005990,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009341,GO:0009987,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0032991,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0071704,GO:1901575,GO:1902494 3.2.1.23,3.2.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000573 275.0
HFD2_k127_5084631_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000001276 197.0
HFD2_k127_5102408_0 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K03183 - 2.1.1.163,2.1.1.201,2.7.1.202 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 608.0
HFD2_k127_5102408_1 PFAM Glutamine synthetase, catalytic K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000935 589.0
HFD2_k127_5102408_10 Belongs to the UPF0145 family - - - 0.000000000000000000000000000000000000000008703 156.0
HFD2_k127_5102408_11 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000004664 157.0
HFD2_k127_5102408_12 - - - - 0.000000000000000000000000000000000001254 149.0
HFD2_k127_5102408_13 MerR HTH family regulatory protein - - - 0.00000000000000000000000000000000005881 143.0
HFD2_k127_5102408_14 Tfp pilus assembly protein FimT - - - 0.000000000004147 73.0
HFD2_k127_5102408_15 - - - - 0.000002018 52.0
HFD2_k127_5102408_17 Peptidase, M16 - - - 0.00003115 55.0
HFD2_k127_5102408_18 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00009488 55.0
HFD2_k127_5102408_2 PFAM Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 517.0
HFD2_k127_5102408_3 Acetyl xylan esterase (AXE1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008969 509.0
HFD2_k127_5102408_4 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 340.0
HFD2_k127_5102408_5 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 331.0
HFD2_k127_5102408_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.000000000000000000000000000000000000000000000000000000000009863 216.0
HFD2_k127_5102408_7 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000001822 218.0
HFD2_k127_5102408_8 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000002314 192.0
HFD2_k127_5102408_9 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000001504 194.0
HFD2_k127_5116308_0 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 576.0
HFD2_k127_5116308_1 COG0798 Arsenite efflux pump ACR3 and related K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 503.0
HFD2_k127_5116308_10 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000004458 105.0
HFD2_k127_5116308_11 regulatory protein, arsR K03892 - - 0.000000000000000001214 89.0
HFD2_k127_5116308_12 COG1520 FOG WD40-like repeat K17713 - - 0.000001029 62.0
HFD2_k127_5116308_13 amine dehydrogenase activity - - - 0.0000037 59.0
HFD2_k127_5116308_3 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008633 363.0
HFD2_k127_5116308_4 phosphoprotein phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 351.0
HFD2_k127_5116308_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 329.0
HFD2_k127_5116308_6 PFAM Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000002784 146.0
HFD2_k127_5116308_7 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000007241 143.0
HFD2_k127_5116308_8 Penicillinase repressor - - - 0.000000000000000000000000000008832 123.0
HFD2_k127_5116308_9 protein kinase activity - - - 0.00000000000000000000000000001819 126.0
HFD2_k127_5160510_0 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 418.0
HFD2_k127_5160510_1 Glycosyl hydrolase family 3 C-terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 425.0
HFD2_k127_5160510_10 TonB-dependent Receptor Plug - - - 0.000000000000000000000000000000000000000000001065 190.0
HFD2_k127_5160510_11 NHL repeat - - - 0.0000000000000000000000000000000000000000003487 175.0
HFD2_k127_5160510_12 Iron-sulphur cluster biosynthesis - - - 0.000000000000000000000000000000000000003298 160.0
HFD2_k127_5160510_13 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000000001648 123.0
HFD2_k127_5160510_14 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000007962 127.0
HFD2_k127_5160510_15 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000000000001902 119.0
HFD2_k127_5160510_16 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000004237 91.0
HFD2_k127_5160510_17 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000851 59.0
HFD2_k127_5160510_18 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0008612 50.0
HFD2_k127_5160510_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 368.0
HFD2_k127_5160510_3 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 381.0
HFD2_k127_5160510_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006468 342.0
HFD2_k127_5160510_5 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007301 336.0
HFD2_k127_5160510_6 MotA/TolQ/ExbB proton channel family K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 326.0
HFD2_k127_5160510_7 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 324.0
HFD2_k127_5160510_8 Transcriptional regulatory protein, C terminal K02483,K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 315.0
HFD2_k127_5160510_9 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000000000000000000000000000000000000000000004345 183.0
HFD2_k127_5167705_0 N-acyl-L-amino acid amidohydrolase K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 406.0
HFD2_k127_5167705_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005928 289.0
HFD2_k127_5167705_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001791 277.0
HFD2_k127_5167705_3 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000739 227.0
HFD2_k127_5212234_0 Major Facilitator Superfamily - - - 1.127e-194 615.0
HFD2_k127_5212234_1 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 332.0
HFD2_k127_5212234_10 zinc ion binding K11997,K12021,K12035 - 2.3.2.27 0.00008526 56.0
HFD2_k127_5212234_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 323.0
HFD2_k127_5212234_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003237 302.0
HFD2_k127_5212234_4 radical SAM domain protein K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000008112 256.0
HFD2_k127_5212234_5 Phospholipase/Carboxylesterase K06999,K15975 - - 0.0000000000000000000000000000000000000000000000000000000000000003496 244.0
HFD2_k127_5212234_6 - - - - 0.000000000000000000000000000000000000000000000000000000001434 214.0
HFD2_k127_5212234_7 Response regulator receiver K02485 - - 0.000000000000000000000000000000000000000000000000000000001619 223.0
HFD2_k127_5212234_8 - - - - 0.00000000000000000000006465 103.0
HFD2_k127_5212234_9 Psort location Cytoplasmic, score 8.87 K01520 - 3.6.1.23 0.00000000001959 77.0
HFD2_k127_522580_0 Peptidase S46 - GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008239,GO:0009056,GO:0009279,GO:0009986,GO:0009987,GO:0016020,GO:0016049,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030154,GO:0030312,GO:0030313,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0040007,GO:0042277,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044462,GO:0044464,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048869,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 2.818e-215 690.0
HFD2_k127_522580_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002706 276.0
HFD2_k127_522580_10 DinB family - - - 0.000666 50.0
HFD2_k127_522580_2 Cytochrome C oxidase, cbb3-type, subunit III K00368 - 1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000671 275.0
HFD2_k127_522580_3 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000001436 217.0
HFD2_k127_522580_4 peptidylprolyl K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000002195 209.0
HFD2_k127_522580_5 LysM domain - - - 0.000000000000000000000000000000000000000000000000000001365 198.0
HFD2_k127_522580_6 GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000002404 176.0
HFD2_k127_522580_7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000008499 148.0
HFD2_k127_522580_8 Transcriptional regulator - - - 0.0000000000000000007556 95.0
HFD2_k127_522580_9 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000006463 58.0
HFD2_k127_5286028_0 Polysaccharide biosynthesis/export protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 508.0
HFD2_k127_5303348_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000002178 221.0
HFD2_k127_5303348_1 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 0.00000000000000000000000000000000000000000008689 164.0
HFD2_k127_5303348_2 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.0000000000001398 74.0
HFD2_k127_530985_0 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 603.0
HFD2_k127_530985_1 COG3119 Arylsulfatase A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009118 545.0
HFD2_k127_530985_10 Thioredoxin-like - - - 0.00000000000000000000000000000000000000004613 168.0
HFD2_k127_530985_11 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000001149 145.0
HFD2_k127_530985_12 - - - - 0.00000000000000000000000004109 121.0
HFD2_k127_530985_13 Sigma-70 region 2 K03088 - - 0.0000000000000000000000001242 112.0
HFD2_k127_530985_14 Domain of unknown function (DUF4382) - - - 0.0000000000000000001498 103.0
HFD2_k127_530985_15 TM2 domain - - - 0.0000000000000000003791 93.0
HFD2_k127_530985_17 COG1651 Protein-disulfide isomerase - - - 0.00001554 54.0
HFD2_k127_530985_2 ATP dependent DNA ligase C terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009726 510.0
HFD2_k127_530985_3 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 365.0
HFD2_k127_530985_4 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 349.0
HFD2_k127_530985_5 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 327.0
HFD2_k127_530985_6 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 345.0
HFD2_k127_530985_7 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000008256 246.0
HFD2_k127_530985_8 lipopolysaccharide-transporting ATPase activity K06861 - - 0.000000000000000000000000000000000000000000000000000000001809 213.0
HFD2_k127_530985_9 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000001414 186.0
HFD2_k127_5360876_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 525.0
HFD2_k127_5360876_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 523.0
HFD2_k127_5360876_10 Belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 324.0
HFD2_k127_5360876_11 PFAM NAD binding domain of 6-phosphogluconate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 297.0
HFD2_k127_5360876_12 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000009328 231.0
HFD2_k127_5360876_13 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000975 188.0
HFD2_k127_5360876_14 EamA-like transporter family K07790 - - 0.000000000000000000000000000000000000001123 159.0
HFD2_k127_5360876_15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000002853 157.0
HFD2_k127_5360876_16 transcriptional activator domain - - - 0.0000000000000000000000000000002819 139.0
HFD2_k127_5360876_17 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000004947 106.0
HFD2_k127_5360876_18 peptidyl-tyrosine sulfation - - - 0.00000000006276 76.0
HFD2_k127_5360876_19 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000001108 69.0
HFD2_k127_5360876_2 PFAM Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009413 516.0
HFD2_k127_5360876_20 ketosteroid isomerase - - - 0.00002472 53.0
HFD2_k127_5360876_21 - - - - 0.00005092 53.0
HFD2_k127_5360876_3 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 489.0
HFD2_k127_5360876_4 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 390.0
HFD2_k127_5360876_5 Associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 374.0
HFD2_k127_5360876_6 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 377.0
HFD2_k127_5360876_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 372.0
HFD2_k127_5360876_8 PFAM Integral membrane protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 353.0
HFD2_k127_5360876_9 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 334.0
HFD2_k127_5388468_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1077.0
HFD2_k127_5388468_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008083 451.0
HFD2_k127_5388468_2 Asparaginase K01444 - 3.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 394.0
HFD2_k127_5388468_3 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 392.0
HFD2_k127_5388468_4 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 317.0
HFD2_k127_5388468_5 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000001153 229.0
HFD2_k127_5388468_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000009809 143.0
HFD2_k127_5388468_7 Methyl-accepting chemotaxis protein signaling domain protein K03406 - - 0.000000000000000000000000000000007811 147.0
HFD2_k127_5388468_8 PDZ domain - - - 0.000000000000000000000001631 115.0
HFD2_k127_5388468_9 Methyl-accepting chemotaxis protein K02660,K11525 - - 0.00000000000000000000001118 117.0
HFD2_k127_5425104_0 Elongation factor G C-terminus K06207 - - 0.00000000000000000000000000000000000000000001011 165.0
HFD2_k127_5425104_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000002475 65.0
HFD2_k127_5425104_3 - - - - 0.00000008219 62.0
HFD2_k127_54491_0 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 474.0
HFD2_k127_54491_1 Bacterial dnaA protein K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 397.0
HFD2_k127_54491_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 298.0
HFD2_k127_54491_3 Small GTP-binding protein K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000276 270.0
HFD2_k127_54491_4 protein-glutamate O-methyltransferase activity K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000008796 287.0
HFD2_k127_54491_5 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000006044 130.0
HFD2_k127_5450984_0 Sodium:sulfate symporter transmembrane region K11106,K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 394.0
HFD2_k127_5450984_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 298.0
HFD2_k127_5450984_2 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000009058 246.0
HFD2_k127_5450984_3 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000002048 252.0
HFD2_k127_5450984_4 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000001016 229.0
HFD2_k127_5450984_5 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000005961 226.0
HFD2_k127_5450984_6 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000002997 176.0
HFD2_k127_5450984_7 Regulator of chromosome condensation (RCC1) repeat - - - 0.00000327 59.0
HFD2_k127_5504696_0 Peptidase S9, prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 621.0
HFD2_k127_5504696_1 Cys/Met metabolism PLP-dependent enzyme K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000002287 264.0
HFD2_k127_5504696_2 Leishmanolysin - - - 0.0000000000000000000000000000000000000000000000000000002851 218.0
HFD2_k127_5504696_3 Leishmanolysin - - - 0.000000000000000000000000000000000000000000000000643 194.0
HFD2_k127_5504696_4 Immune inhibitor A peptidase M6 - - - 0.00000000000000000000000000000000000000005253 174.0
HFD2_k127_5504696_5 PFAM PAP2 superfamily K19302 - 3.6.1.27 0.0000000000000002306 89.0
HFD2_k127_552090_0 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 384.0
HFD2_k127_552090_10 - K02450 - - 0.00000000000000000000000000000006644 135.0
HFD2_k127_552090_11 - - - - 0.0000000000000000000000000000009039 136.0
HFD2_k127_552090_12 1,4-alpha-glucan branching enzyme activity K00700 - 2.4.1.18 0.000000000000000000000000000002049 128.0
HFD2_k127_552090_13 Domain of unknown function (DUF4382) - - - 0.0001129 53.0
HFD2_k127_552090_2 aminopeptidase activity K07004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004606 278.0
HFD2_k127_552090_3 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000001191 248.0
HFD2_k127_552090_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000007288 246.0
HFD2_k127_552090_5 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000009081 206.0
HFD2_k127_552090_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.000000000000000000000000000000000000000000000000000001157 199.0
HFD2_k127_552090_7 SMART Transcription regulator, AsnC-type K03718,K03719 - - 0.0000000000000000000000000000000000000000000005076 171.0
HFD2_k127_552090_8 - - - - 0.000000000000000000000000000000000000000002082 170.0
HFD2_k127_552090_9 Diacylglycerol kinase catalytic domain K07029 GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.107 0.00000000000000000000000000000000000003178 154.0
HFD2_k127_5527897_0 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 488.0
HFD2_k127_5527897_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 414.0
HFD2_k127_5527897_2 Beta-lactamase class C and other penicillin binding - - - 0.000000000000000000000000000000000000000000000000001011 206.0
HFD2_k127_5527897_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000003173 96.0
HFD2_k127_5527897_4 - - - - 0.00000000000002529 82.0
HFD2_k127_5527897_5 - - - - 0.000000111 59.0
HFD2_k127_5527897_6 - - - - 0.00003454 56.0
HFD2_k127_5647396_0 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 5.907e-206 676.0
HFD2_k127_5647396_1 PFAM Glucose Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007244 412.0
HFD2_k127_565056_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.217e-292 910.0
HFD2_k127_565056_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 527.0
HFD2_k127_565056_10 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005777 272.0
HFD2_k127_565056_11 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002352 243.0
HFD2_k127_565056_12 bacterial-type flagellum-dependent cell motility K01317 - 3.4.21.10 0.00000000000000000000000000000000000000000000000000000000000134 233.0
HFD2_k127_565056_13 - - - - 0.00000000000000000000002421 114.0
HFD2_k127_565056_14 Bacterial regulatory proteins, tetR family - - - 0.00000000000000006959 88.0
HFD2_k127_565056_15 OmpA family K03286 - - 0.0000000001708 74.0
HFD2_k127_565056_2 Cys/Met metabolism PLP-dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 454.0
HFD2_k127_565056_3 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 393.0
HFD2_k127_565056_4 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 337.0
HFD2_k127_565056_5 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008247 332.0
HFD2_k127_565056_6 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 295.0
HFD2_k127_565056_7 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002417 278.0
HFD2_k127_565056_8 Part of the ABC transporter FtsEX involved in K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000342 275.0
HFD2_k127_565056_9 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000003954 261.0
HFD2_k127_56637_0 RmlD substrate binding domain K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 341.0
HFD2_k127_56637_1 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000002961 227.0
HFD2_k127_56637_2 Aminotransferase class-V K04487 - 2.8.1.7 0.0000000000000000000000000000000000000001083 156.0
HFD2_k127_5668309_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.127e-298 964.0
HFD2_k127_5668309_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 4.403e-290 908.0
HFD2_k127_5668309_2 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000009622 182.0
HFD2_k127_5668309_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0000000003386 60.0
HFD2_k127_5683413_0 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 466.0
HFD2_k127_5683413_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000001416 138.0
HFD2_k127_5683413_2 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000000000000292 138.0
HFD2_k127_5683413_3 Domain of unknown function (DUF1844) - - - 0.0000002511 56.0
HFD2_k127_5683413_4 - - - - 0.000001513 61.0
HFD2_k127_5716093_0 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 3.549e-231 736.0
HFD2_k127_5716093_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 367.0
HFD2_k127_5716093_2 argininosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005911 304.0
HFD2_k127_5716093_3 Regulates arginine biosynthesis genes K03402 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000002042 126.0
HFD2_k127_5716093_4 HIT domain K02503 - - 0.00000001501 58.0
HFD2_k127_5767044_0 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005212 612.0
HFD2_k127_5767044_1 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000002111 212.0
HFD2_k127_5767044_2 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 0.0000000000000000005563 96.0
HFD2_k127_5770968_0 Penicillin amidase K01434 - 3.5.1.11 8.751e-207 680.0
HFD2_k127_5770968_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.912e-201 635.0
HFD2_k127_5770968_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 340.0
HFD2_k127_5770968_3 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 312.0
HFD2_k127_5770968_4 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009021 308.0
HFD2_k127_5770968_5 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000006043 245.0
HFD2_k127_5770968_6 - - - - 0.0000000007142 65.0
HFD2_k127_5770968_8 Belongs to the peptidase S8 family - - - 0.000008664 59.0
HFD2_k127_5819953_0 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 340.0
HFD2_k127_5819953_1 Beta-lactamase K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 314.0
HFD2_k127_5819953_2 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000003056 178.0
HFD2_k127_5824890_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006395 598.0
HFD2_k127_5824890_1 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 511.0
HFD2_k127_5824890_10 domain, Protein K01179,K07260,K13735 - 3.2.1.4,3.4.17.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 316.0
HFD2_k127_5824890_11 histidine kinase A domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000378 284.0
HFD2_k127_5824890_12 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000306 254.0
HFD2_k127_5824890_13 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000103 250.0
HFD2_k127_5824890_14 PFAM oxidoreductase, molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000001396 236.0
HFD2_k127_5824890_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000006839 220.0
HFD2_k127_5824890_16 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.00000000000000000000000000000000000000000000000000000001542 212.0
HFD2_k127_5824890_17 Glycosyl transferase family 2 K08301 - - 0.0000000000000000000000000000000000000000000000003079 185.0
HFD2_k127_5824890_18 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000007499 185.0
HFD2_k127_5824890_19 - - - - 0.000000000000000000004992 100.0
HFD2_k127_5824890_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 436.0
HFD2_k127_5824890_20 - - - - 0.000000000000000002779 90.0
HFD2_k127_5824890_21 Putative regulatory protein - - - 0.0000000000271 66.0
HFD2_k127_5824890_22 long-chain fatty acid transport protein - - - 0.000000001076 69.0
HFD2_k127_5824890_23 - - - - 0.0001019 51.0
HFD2_k127_5824890_3 Belongs to the Glu Leu Phe Val dehydrogenases family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006694 438.0
HFD2_k127_5824890_4 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009302 442.0
HFD2_k127_5824890_5 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 394.0
HFD2_k127_5824890_6 aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 395.0
HFD2_k127_5824890_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 372.0
HFD2_k127_5824890_8 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 371.0
HFD2_k127_5824890_9 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 363.0
HFD2_k127_5848173_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 394.0
HFD2_k127_5848173_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 344.0
HFD2_k127_5848173_2 Acyl transferase domain K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 308.0
HFD2_k127_5848173_3 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 302.0
HFD2_k127_5848173_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000001078 111.0
HFD2_k127_5848173_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000002906 93.0
HFD2_k127_5858394_0 Involved in the tonB-independent uptake of proteins - - - 4.512e-279 897.0
HFD2_k127_5858394_1 Dihydroxyacetone kinase family K07030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 349.0
HFD2_k127_5858394_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000002628 151.0
HFD2_k127_5858394_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000554 137.0
HFD2_k127_5858394_4 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000002878 113.0
HFD2_k127_5858394_5 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000008007 102.0
HFD2_k127_5858394_6 Binds to the 23S rRNA K02939 - - 0.00000000000000008791 93.0
HFD2_k127_5858394_7 Sporulation related domain - - - 0.000000000000006073 87.0
HFD2_k127_5858394_8 Binds to the 23S rRNA K02939 - - 0.00000000000002281 73.0
HFD2_k127_5858394_9 - - - - 0.000000002849 68.0
HFD2_k127_5860779_0 ABC transporter transmembrane region K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 403.0
HFD2_k127_5860779_1 - - - - 0.000000000000000000000006899 112.0
HFD2_k127_5863378_0 TonB-dependent receptor K02014 - - 4.858e-234 763.0
HFD2_k127_5863378_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 528.0
HFD2_k127_5863378_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 408.0
HFD2_k127_5863378_3 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005845 256.0
HFD2_k127_5863378_4 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000004801 177.0
HFD2_k127_5863378_5 PFAM DSBA oxidoreductase - - - 0.000000000000000000000000000005065 138.0
HFD2_k127_5863378_6 Transferase K02527 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000009059 127.0
HFD2_k127_5863378_7 LVIVD repeat - - - 0.0006984 52.0
HFD2_k127_5873612_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 2.546e-305 976.0
HFD2_k127_5873612_1 Pfam:KaiC K08482 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009307 611.0
HFD2_k127_5873612_10 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 339.0
HFD2_k127_5873612_11 Histidinol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 363.0
HFD2_k127_5873612_12 Peptidase family M23 K21472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 332.0
HFD2_k127_5873612_13 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 309.0
HFD2_k127_5873612_14 Imidazoleglycerol-phosphate dehydratase K00817,K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9,3.1.3.15,4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000006907 247.0
HFD2_k127_5873612_15 Histidine kinase K07683 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000245 230.0
HFD2_k127_5873612_16 Inositol monophosphatase family K01092,K05602 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000002639 227.0
HFD2_k127_5873612_17 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000001691 193.0
HFD2_k127_5873612_18 response regulator K07782 - - 0.000000000000000000000000000000000000000000000000001212 193.0
HFD2_k127_5873612_19 response regulator K07782 - - 0.000000000000000000000000000000000000000000000000002158 191.0
HFD2_k127_5873612_2 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 570.0
HFD2_k127_5873612_20 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000002205 179.0
HFD2_k127_5873612_21 - - - - 0.00000000000000000000000000000000000000001352 160.0
HFD2_k127_5873612_22 Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000003861 173.0
HFD2_k127_5873612_23 Belongs to the acetyltransferase family. ArgA subfamily K00619 - 2.3.1.1 0.00000000000000000000000000000004293 141.0
HFD2_k127_5873612_24 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K07112 - - 0.00000000000000000000000000000005944 138.0
HFD2_k127_5873612_25 KaiB K08481 - - 0.0000000000000000000000000000004187 136.0
HFD2_k127_5873612_26 - - - - 0.000000000000000000000001589 105.0
HFD2_k127_5873612_27 OmpA family K03640 - - 0.00000000000000000000001072 115.0
HFD2_k127_5873612_3 electron transfer activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 515.0
HFD2_k127_5873612_4 arylsulfatase activity K01132 - 3.1.6.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 465.0
HFD2_k127_5873612_5 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009196 473.0
HFD2_k127_5873612_6 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009682 445.0
HFD2_k127_5873612_7 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 424.0
HFD2_k127_5873612_8 phosphoribosyl-ATP diphosphatase activity K00765,K01663,K08736,K11755,K14152 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0004399,GO:0004635,GO:0004636,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016462,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016757,GO:0016763,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,2.4.2.17,3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 387.0
HFD2_k127_5873612_9 Trypsin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 353.0
HFD2_k127_5873955_0 metalloendopeptidase activity K01283 - 3.4.15.1 2.139e-259 818.0
HFD2_k127_5873955_1 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 438.0
HFD2_k127_5873955_10 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000004761 208.0
HFD2_k127_5873955_11 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000007587 198.0
HFD2_k127_5873955_12 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000001952 192.0
HFD2_k127_5873955_13 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000007642 161.0
HFD2_k127_5873955_14 Peptidase family M28 - - - 0.00000000000000000000000000000000000000007169 173.0
HFD2_k127_5873955_15 Protein of unknown function, DUF - - - 0.0000000000000000000000000000000000000136 146.0
HFD2_k127_5873955_16 Iron-sulfur cluster assembly protein - - - 0.00000000000000000000000000000000000403 139.0
HFD2_k127_5873955_17 Matrixin - - - 0.00000000000000000000000000000000001191 147.0
HFD2_k127_5873955_18 Prephenate dehydrogenase - - - 0.00000000000000000000000000000000001422 148.0
HFD2_k127_5873955_19 Cupin domain - - - 0.0000000000000000000000000000001192 127.0
HFD2_k127_5873955_2 Drug exporters of the RND superfamily K06994,K07003,K20466,K20470 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009273,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0040007,GO:0042546,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071554,GO:0071702,GO:0071766,GO:0071840,GO:0071944,GO:1901264 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 370.0
HFD2_k127_5873955_20 Thioesterase K07107,K12500 - - 0.000000000000000793 90.0
HFD2_k127_5873955_21 - - - - 0.00000000000444 68.0
HFD2_k127_5873955_22 OsmC-like protein - - - 0.00000005767 57.0
HFD2_k127_5873955_23 PQQ-like domain - - - 0.0000008557 62.0
HFD2_k127_5873955_24 Chorismate mutase type II K04093 - 5.4.99.5 0.0000398 49.0
HFD2_k127_5873955_3 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006509 335.0
HFD2_k127_5873955_4 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 336.0
HFD2_k127_5873955_5 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 299.0
HFD2_k127_5873955_6 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006674 271.0
HFD2_k127_5873955_7 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002087 267.0
HFD2_k127_5873955_8 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000354 257.0
HFD2_k127_5873955_9 tRNA wobble adenosine to inosine editing - - - 0.000000000000000000000000000000000000000000000000000000000000000001728 231.0
HFD2_k127_5911655_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1164.0
HFD2_k127_5911655_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009749 338.0
HFD2_k127_5911655_10 COG2217 Cation transport ATPase K01534 - 3.6.3.3,3.6.3.5 0.000952 47.0
HFD2_k127_5911655_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 300.0
HFD2_k127_5911655_3 - K12065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007192 296.0
HFD2_k127_5911655_4 Transcriptional regulator, arsR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000182 259.0
HFD2_k127_5911655_5 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001448 237.0
HFD2_k127_5911655_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000009204 166.0
HFD2_k127_5911655_7 DsrE/DsrF-like family K06039 - - 0.0000000000000000000000000000000000002532 154.0
HFD2_k127_5911655_8 FMN binding K03612 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000009 130.0
HFD2_k127_5993727_0 Beta-L-arabinofuranosidase, GH127 K09955 - - 4.128e-272 866.0
HFD2_k127_5993727_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 4.732e-229 739.0
HFD2_k127_5993727_10 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.00000000000000000000000000000000000000000000000009345 181.0
HFD2_k127_5993727_11 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000001861 184.0
HFD2_k127_5993727_12 protoporphyrinogen oxidase activity K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000008623 182.0
HFD2_k127_5993727_13 Rhomboid family - - - 0.0000000000000000000000000000000000001766 151.0
HFD2_k127_5993727_14 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000000009986 113.0
HFD2_k127_5993727_15 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000807 102.0
HFD2_k127_5993727_16 Sporulation related domain - - - 0.000000000000000001044 99.0
HFD2_k127_5993727_17 chaperone-mediated protein folding K21007 - - 0.00002923 57.0
HFD2_k127_5993727_2 Domain in cystathionine beta-synthase and other proteins. K01697 - 4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005875 593.0
HFD2_k127_5993727_3 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 492.0
HFD2_k127_5993727_4 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 425.0
HFD2_k127_5993727_5 Zn-dependent protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 346.0
HFD2_k127_5993727_6 D-ala D-ala ligase C-terminus K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006874 335.0
HFD2_k127_5993727_7 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 319.0
HFD2_k127_5993727_8 ECF sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 296.0
HFD2_k127_5993727_9 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000005434 207.0
HFD2_k127_601490_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.104e-250 788.0
HFD2_k127_601490_1 Endoribonuclease that initiates mRNA decay K18682 - - 1.679e-209 663.0
HFD2_k127_601490_10 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000005649 265.0
HFD2_k127_601490_11 - - - - 0.00000000006542 75.0
HFD2_k127_601490_12 - - - - 0.0000002437 56.0
HFD2_k127_601490_13 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00004881 53.0
HFD2_k127_601490_14 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0001323 54.0
HFD2_k127_601490_2 B3/4 domain K01890 - 6.1.1.20 6.051e-202 659.0
HFD2_k127_601490_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 490.0
HFD2_k127_601490_4 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 370.0
HFD2_k127_601490_5 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 349.0
HFD2_k127_601490_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009416 356.0
HFD2_k127_601490_7 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 327.0
HFD2_k127_601490_8 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003544 272.0
HFD2_k127_601490_9 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000002668 258.0
HFD2_k127_6016838_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.101e-235 746.0
HFD2_k127_6016838_1 membrane organization - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 624.0
HFD2_k127_6016838_10 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002119 263.0
HFD2_k127_6016838_11 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001587 244.0
HFD2_k127_6016838_12 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000006844 206.0
HFD2_k127_6016838_13 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000002709 171.0
HFD2_k127_6016838_14 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.0000000000000000000000000000000000000000008774 169.0
HFD2_k127_6016838_15 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000004713 162.0
HFD2_k127_6016838_16 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000002466 150.0
HFD2_k127_6016838_17 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000005545 159.0
HFD2_k127_6016838_18 Mo-molybdopterin cofactor metabolic process K02379 - - 0.000000000000000000000000000001309 132.0
HFD2_k127_6016838_19 - - - - 0.000000000000000000000001549 110.0
HFD2_k127_6016838_2 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 482.0
HFD2_k127_6016838_20 molybdopterin-guanine dinucleotide biosynthesis protein K03753,K13818 - 2.7.7.77 0.0000000000000000000000205 114.0
HFD2_k127_6016838_21 - - - - 0.0000000000000000002428 96.0
HFD2_k127_6016838_22 - - - - 0.000000000000005406 80.0
HFD2_k127_6016838_23 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000002942 76.0
HFD2_k127_6016838_3 ATP:ADP antiporter activity K01932,K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005521 391.0
HFD2_k127_6016838_4 chromate transport K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 374.0
HFD2_k127_6016838_5 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007238 372.0
HFD2_k127_6016838_6 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 377.0
HFD2_k127_6016838_7 ornithine cyclodeaminase activity K01750,K18258,K19244 - 1.4.1.1,1.5.1.25,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 336.0
HFD2_k127_6016838_8 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 332.0
HFD2_k127_6016838_9 ATP ADP translocase K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 316.0
HFD2_k127_6028077_0 Glycosyltransferase like family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009528 353.0
HFD2_k127_6028077_1 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 294.0
HFD2_k127_6028077_10 PEP-CTERM motif - - - 0.00008589 53.0
HFD2_k127_6028077_2 Protein involved in cellulose biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001808 301.0
HFD2_k127_6028077_3 ATP-grasp - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009322 288.0
HFD2_k127_6028077_4 Protein involved in cellulose biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002084 279.0
HFD2_k127_6028077_5 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000005042 242.0
HFD2_k127_6028077_6 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.00000000000000000000000000000000636 142.0
HFD2_k127_6028077_8 Sulfotransferase family - - - 0.0000000000000000000000000307 121.0
HFD2_k127_6028077_9 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000007466 65.0
HFD2_k127_6034111_0 Dienelactone hydrolase family - - - 1.239e-297 933.0
HFD2_k127_6034111_1 Bacterial protein of unknown function (DUF885) - - - 8.783e-201 647.0
HFD2_k127_6034111_2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 462.0
HFD2_k127_6034111_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03918 - 2.6.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 458.0
HFD2_k127_6034111_4 Protein of unknown function (DUF1569) - - - 0.0000000000000000000000000000000008947 140.0
HFD2_k127_6048711_0 Zinc carboxypeptidase - - - 3.31e-310 973.0
HFD2_k127_6048711_1 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 1.643e-197 629.0
HFD2_k127_6048711_2 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 518.0
HFD2_k127_6048711_3 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 335.0
HFD2_k127_6048711_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001549 271.0
HFD2_k127_6048711_5 histidine kinase A domain protein domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000009008 255.0
HFD2_k127_6048852_0 6-phosphogluconolactonase activity - - - 0.0 1071.0
HFD2_k127_6048852_1 radical SAM domain protein - - - 1.22e-213 676.0
HFD2_k127_6048852_2 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001999 264.0
HFD2_k127_6048852_3 TonB dependent receptor K02014,K16092 - - 0.000000000000000000000000000000000000000000000000000008059 214.0
HFD2_k127_6048852_5 Major facilitator Superfamily K06610,K08162 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000001339 73.0
HFD2_k127_6054802_0 aminopeptidase activity - - - 3.639e-216 684.0
HFD2_k127_6054802_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 492.0
HFD2_k127_6054802_2 Aminotransferase class I and II K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006489 458.0
HFD2_k127_6054802_3 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 430.0
HFD2_k127_6054802_4 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000000000000000192 227.0
HFD2_k127_6054802_5 Collagenase K01387 - 3.4.24.3 0.00000000000002535 85.0
HFD2_k127_6054802_6 PFAM PQQ enzyme repeat - - - 0.000000000000206 83.0
HFD2_k127_6077633_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.637e-259 817.0
HFD2_k127_6077633_1 Cys/Met metabolism PLP-dependent enzyme K01758 - 4.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 526.0
HFD2_k127_6077633_10 Maf-like protein K06287 - - 0.000000000000000000000000006285 115.0
HFD2_k127_6077633_11 DnaJ molecular chaperone homology domain - - - 0.000000000000004581 87.0
HFD2_k127_6077633_12 Putative zinc-binding metallo-peptidase - - - 0.0006186 51.0
HFD2_k127_6077633_2 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840 - 5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 518.0
HFD2_k127_6077633_3 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 373.0
HFD2_k127_6077633_4 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 346.0
HFD2_k127_6077633_5 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 349.0
HFD2_k127_6077633_6 GIY-YIG type nucleases (URI domain) K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008841 276.0
HFD2_k127_6077633_7 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000009078 253.0
HFD2_k127_6077633_8 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000001122 181.0
HFD2_k127_6077633_9 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000002159 150.0
HFD2_k127_6078395_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 9.157e-320 992.0
HFD2_k127_6078395_1 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 510.0
HFD2_k127_6078395_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 509.0
HFD2_k127_6078395_3 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000004044 138.0
HFD2_k127_6078395_4 - - - - 0.00000000000000000001692 101.0
HFD2_k127_6081538_0 metallocarboxypeptidase activity K14054 - - 0.0 1351.0
HFD2_k127_6081538_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 421.0
HFD2_k127_6081538_2 Caspase domain - - - 0.000000000000000000000003181 120.0
HFD2_k127_6081538_3 membrane transporter protein K07090 - - 0.00000000000000000001879 108.0
HFD2_k127_6084977_0 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 385.0
HFD2_k127_6084977_1 ORF6N domain - - - 0.000000000000000000000000000000000000003139 168.0
HFD2_k127_6084977_2 regulation of single-species biofilm formation K13572,K13573 - - 0.000000000000000000000000000000005851 141.0
HFD2_k127_6084977_3 transcriptional regulator K13573 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000301 69.0
HFD2_k127_6131336_0 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009672 516.0
HFD2_k127_6131336_1 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001323 287.0
HFD2_k127_6131336_2 - - - - 0.0000000000000000000000000000000000000000008607 161.0
HFD2_k127_6146583_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 291.0
HFD2_k127_6146583_1 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000101 269.0
HFD2_k127_6146583_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000037 158.0
HFD2_k127_6146583_3 Glycosyl transferases group 1 - - - 0.0000000000000000000000003084 120.0
HFD2_k127_6154202_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 519.0
HFD2_k127_6154202_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005915 464.0
HFD2_k127_6154202_2 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004274 269.0
HFD2_k127_6154202_3 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000003822 258.0
HFD2_k127_6154202_4 ABC transporter, ATP-binding protein K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000004473 245.0
HFD2_k127_6154202_5 NUDIX domain - - - 0.00000000000000000000000000000000000000000003627 168.0
HFD2_k127_6154202_6 Helix-turn-helix domain - - - 0.000000000000000000000000001345 120.0
HFD2_k127_6154202_8 - - - - 0.0000001014 55.0
HFD2_k127_6154202_9 alginic acid biosynthetic process K10297 - - 0.0000003583 51.0
HFD2_k127_6163807_0 3-phosphoshikimate 1-carboxyvinyltransferase activity K00800 GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 371.0
HFD2_k127_6163807_1 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0040007,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000005826 179.0
HFD2_k127_6163807_2 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000002335 128.0
HFD2_k127_6163807_3 - - - - 0.0000000000000000000000132 102.0
HFD2_k127_6163807_4 membrane transporter protein K07090 - - 0.00000000000000002605 86.0
HFD2_k127_6163807_5 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000006313 78.0
HFD2_k127_6163807_6 - - - - 0.00000000000002166 73.0
HFD2_k127_6163807_7 BON domain - - - 0.00000006206 63.0
HFD2_k127_6187964_0 Major facilitator superfamily MFS_1 K02445 - - 0.00000000000000000000000000000000000000000000000000000008049 203.0
HFD2_k127_6187964_1 domain protein - - - 0.00000000000000000000000000000000000000000000000003033 202.0
HFD2_k127_621647_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 403.0
HFD2_k127_621647_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 374.0
HFD2_k127_621647_2 PTS system mannose/fructose/sorbose family IID component K02796 - - 0.000000000000000000000000000000000000000000000006995 189.0
HFD2_k127_621647_3 PTS system sorbose subfamily IIB component K19507 - - 0.000000000000000000000000000000000000003002 156.0
HFD2_k127_621647_4 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000002687 137.0
HFD2_k127_621647_5 PTS system sorbose-specific iic component K02795 - - 0.00000000000000000005897 99.0
HFD2_k127_621647_6 PTS HPr component phosphorylation site K11189 - - 0.0000000000000000002636 102.0
HFD2_k127_621647_7 PTS system fructose IIA component - - - 0.00000002368 61.0
HFD2_k127_6233378_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 1.755e-301 952.0
HFD2_k127_6233378_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 3.181e-200 644.0
HFD2_k127_6233378_10 Bacterial Ig-like domain - - - 0.00000000000000000000000000000000000000000000002228 197.0
HFD2_k127_6233378_11 - - - - 0.0000000000000000000000000000001205 132.0
HFD2_k127_6233378_12 BioY family K03523 - - 0.0000000000000000000000000009918 123.0
HFD2_k127_6233378_13 - - - - 0.00000000000000000000000005035 108.0
HFD2_k127_6233378_14 CAAX protease self-immunity K07052 - - 0.000000000000000000003648 108.0
HFD2_k127_6233378_15 Domain of unknown function (DUF4173) - - - 0.0000001685 61.0
HFD2_k127_6233378_2 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 614.0
HFD2_k127_6233378_3 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004902 562.0
HFD2_k127_6233378_4 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 531.0
HFD2_k127_6233378_5 secondary active sulfate transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 524.0
HFD2_k127_6233378_6 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008161 428.0
HFD2_k127_6233378_7 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 402.0
HFD2_k127_6233378_8 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 374.0
HFD2_k127_6233378_9 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000004474 219.0
HFD2_k127_6263801_0 heavy metal translocating P-type ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 2.497e-217 702.0
HFD2_k127_6263801_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 3.02e-212 666.0
HFD2_k127_6263801_10 FAD binding domain K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 304.0
HFD2_k127_6263801_11 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007596 284.0
HFD2_k127_6263801_12 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000323 211.0
HFD2_k127_6263801_13 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000001152 203.0
HFD2_k127_6263801_14 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000187 220.0
HFD2_k127_6263801_15 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000002262 205.0
HFD2_k127_6263801_16 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000001773 190.0
HFD2_k127_6263801_17 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000002137 189.0
HFD2_k127_6263801_18 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000000000003444 183.0
HFD2_k127_6263801_19 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000008452 181.0
HFD2_k127_6263801_2 Fumarase C C-terminus K01744 - 4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 609.0
HFD2_k127_6263801_20 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000002746 142.0
HFD2_k127_6263801_21 Cupredoxin-like domain - - - 0.00000000000000000000404 108.0
HFD2_k127_6263801_22 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000001345 91.0
HFD2_k127_6263801_23 - - - - 0.00000000000000002798 97.0
HFD2_k127_6263801_24 - - - - 0.0000000000000001344 91.0
HFD2_k127_6263801_26 Ribosomal protein L36 K02919 - - 0.0000000000000427 74.0
HFD2_k127_6263801_27 Heavy metal transport detoxification protein K07213 - - 0.0000000000001675 72.0
HFD2_k127_6263801_28 Redoxin K03564 - 1.11.1.15 0.0000000000001806 74.0
HFD2_k127_6263801_29 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K00999 GO:0003674,GO:0003824,GO:0003881,GO:0003882,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.11,2.7.8.5 0.0000000008182 64.0
HFD2_k127_6263801_3 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 517.0
HFD2_k127_6263801_30 GDP-mannose 4,6 dehydratase - - - 0.0000004558 62.0
HFD2_k127_6263801_31 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0003492 51.0
HFD2_k127_6263801_4 Transketolase, pyrimidine binding domain K00167,K11381,K21417 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 501.0
HFD2_k127_6263801_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 448.0
HFD2_k127_6263801_6 ThiF family K21029,K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 445.0
HFD2_k127_6263801_7 e3 binding domain K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 433.0
HFD2_k127_6263801_8 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 415.0
HFD2_k127_6263801_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 298.0
HFD2_k127_6281813_0 DNA polymerase X family K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007432 546.0
HFD2_k127_6281813_1 GH3 auxin-responsive promoter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 349.0
HFD2_k127_6281813_2 - - - - 0.0000000000000000000000000000000000000000004226 179.0
HFD2_k127_6281813_3 s1 p1 nuclease K05986 - 3.1.30.1 0.000000000000000000000000000000000000001395 158.0
HFD2_k127_6281813_4 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.000000000000000000000000000000000001081 143.0
HFD2_k127_6281813_5 Ring-hydroxylating dioxygenase, large terminal subunit - - - 0.00000000000000000000000000000000008149 154.0
HFD2_k127_6281813_6 acetyltransferase K00014 - 1.1.1.25 0.00002071 56.0
HFD2_k127_6333113_0 protein phosphatase 2C domain protein - - - 2.041e-206 661.0
HFD2_k127_6333113_1 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000004465 158.0
HFD2_k127_6333113_2 - - - - 0.000000000000000000000000000000248 127.0
HFD2_k127_6333113_3 - - - - 0.000000000000000000417 91.0
HFD2_k127_6333113_4 - - - - 0.00000000000007745 74.0
HFD2_k127_6333113_5 Transposase IS116 IS110 IS902 - - - 0.00000000008027 65.0
HFD2_k127_6333113_6 Resolvase, N terminal domain - - - 0.000000276 54.0
HFD2_k127_6353058_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 0.0 1012.0
HFD2_k127_6353058_1 Prolyl oligopeptidase family - - - 4.291e-242 779.0
HFD2_k127_6353058_10 Sulfurtransferase - - - 0.0000000000000003299 79.0
HFD2_k127_6353058_2 Peptidase family M28 - - - 9.315e-202 644.0
HFD2_k127_6353058_3 succinyl-diaminopimelate desuccinylase activity K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 417.0
HFD2_k127_6353058_4 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 360.0
HFD2_k127_6353058_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000005656 255.0
HFD2_k127_6353058_6 - K00241 - - 0.000000000000000000000000000000000000000000000000000000000000001007 226.0
HFD2_k127_6353058_7 heme binding - - - 0.0000000000000000000000000000000000000000000005437 192.0
HFD2_k127_6353058_8 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000001432 129.0
HFD2_k127_6353058_9 FtsX-like permease family K02004 - - 0.0000000000000000000000000000006019 138.0
HFD2_k127_640819_0 WD domain, G-beta repeat K12132 - 2.7.11.1 0.00000000000000000005308 99.0
HFD2_k127_640819_1 FHA domain protein - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 - 0.000000008957 65.0
HFD2_k127_640819_2 PFAM FHA domain - - - 0.0000004161 60.0
HFD2_k127_641431_0 Extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000005139 251.0
HFD2_k127_641431_1 Belongs to the ABC transporter superfamily K10112 - - 0.0000001336 57.0
HFD2_k127_6466712_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 9.555e-283 882.0
HFD2_k127_6466712_1 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007502 274.0
HFD2_k127_6476600_0 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 583.0
HFD2_k127_6476600_1 Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009467 514.0
HFD2_k127_6476600_2 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007689 517.0
HFD2_k127_6476600_3 Permease MlaE K02066 - - 0.000000000000000000000000000000000008839 144.0
HFD2_k127_6476600_4 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000002466 125.0
HFD2_k127_6476600_5 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000009368 94.0
HFD2_k127_6476600_6 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 0.0000000000003078 82.0
HFD2_k127_6520561_0 serine-type peptidase activity K01278 - 3.4.14.5 8.286e-290 920.0
HFD2_k127_6520561_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000003288 242.0
HFD2_k127_6520561_2 PFAM regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000000000000000000000000003807 228.0
HFD2_k127_6520561_3 membrane transporter protein K07090 - - 0.0000000000000000000000000000003025 129.0
HFD2_k127_6602132_0 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 374.0
HFD2_k127_6602132_1 BlaR1 peptidase M56 - - - 0.00000000000000000000000000000004171 145.0
HFD2_k127_6602132_2 deoxyhypusine monooxygenase activity - - - 0.00006123 56.0
HFD2_k127_6619026_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.395e-284 890.0
HFD2_k127_6619026_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.435e-231 736.0
HFD2_k127_6619026_10 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 420.0
HFD2_k127_6619026_11 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 436.0
HFD2_k127_6619026_12 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 400.0
HFD2_k127_6619026_13 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 361.0
HFD2_k127_6619026_14 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 377.0
HFD2_k127_6619026_15 Ribosomal protein S2 K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 346.0
HFD2_k127_6619026_16 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 321.0
HFD2_k127_6619026_17 CoA carboxylase activity K01968 - 6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 312.0
HFD2_k127_6619026_18 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 305.0
HFD2_k127_6619026_19 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000006083 253.0
HFD2_k127_6619026_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 1.993e-206 659.0
HFD2_k127_6619026_20 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000003557 242.0
HFD2_k127_6619026_21 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000000003627 248.0
HFD2_k127_6619026_22 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000001738 223.0
HFD2_k127_6619026_23 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000003668 230.0
HFD2_k127_6619026_24 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000001558 232.0
HFD2_k127_6619026_25 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000003813 214.0
HFD2_k127_6619026_26 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000007453 217.0
HFD2_k127_6619026_27 Ribosomal protein S9/S16 K02996 - - 0.0000000000000000000000000000000000000000000000001419 183.0
HFD2_k127_6619026_28 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000002099 176.0
HFD2_k127_6619026_29 rod shape-determining protein MreC K03570 - - 0.0000000000000000000000000000000000000001048 161.0
HFD2_k127_6619026_3 Hsp70 protein K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 587.0
HFD2_k127_6619026_30 diguanylate cyclase - - - 0.000000000000000000000000000000001585 146.0
HFD2_k127_6619026_31 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000001433 137.0
HFD2_k127_6619026_32 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000002432 139.0
HFD2_k127_6619026_33 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000236 119.0
HFD2_k127_6619026_34 Biotin-requiring enzyme - - - 0.00000000000000000000000005862 123.0
HFD2_k127_6619026_35 rod shape-determining protein MreD K03571 - - 0.0000000000000000000000002116 120.0
HFD2_k127_6619026_36 PFAM Radical SAM - - - 0.00000000000000000000004608 114.0
HFD2_k127_6619026_4 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 555.0
HFD2_k127_6619026_5 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 551.0
HFD2_k127_6619026_6 Drug exporters of the RND superfamily K06994,K07003,K20466,K20470 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009273,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0040007,GO:0042546,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071554,GO:0071702,GO:0071766,GO:0071840,GO:0071944,GO:1901264 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 467.0
HFD2_k127_6619026_7 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 425.0
HFD2_k127_6619026_8 radical SAM domain protein K06137,K06138 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 423.0
HFD2_k127_6619026_9 Cell cycle protein K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 420.0
HFD2_k127_663228_0 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000002194 257.0
HFD2_k127_663228_1 beta-galactosidase K01190 - 3.2.1.23 0.000000000000000000000000000001427 124.0
HFD2_k127_663228_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.00000000000000000000000008267 111.0
HFD2_k127_6635860_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 391.0
HFD2_k127_6635860_1 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000006221 225.0
HFD2_k127_6695699_0 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 9.797e-292 915.0
HFD2_k127_6695699_1 Fibronectin type III-like domain K05349 - 3.2.1.21 1.301e-290 919.0
HFD2_k127_6695699_10 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 560.0
HFD2_k127_6695699_11 Band 7 protein K07192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 529.0
HFD2_k127_6695699_12 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 520.0
HFD2_k127_6695699_13 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 444.0
HFD2_k127_6695699_14 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 445.0
HFD2_k127_6695699_15 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006983 387.0
HFD2_k127_6695699_16 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009321 389.0
HFD2_k127_6695699_17 COG1294 Cytochrome bd-type quinol oxidase subunit 2 K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 392.0
HFD2_k127_6695699_18 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 345.0
HFD2_k127_6695699_19 Zinc carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003548 289.0
HFD2_k127_6695699_2 5TM C-terminal transporter carbon starvation CstA K06200 - - 1.615e-268 841.0
HFD2_k127_6695699_20 4 iron, 4 sulfur cluster binding K04014,K08353,K08358,K16293 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044464,GO:0055114,GO:0098809 - 0.00000000000000000000000000000000000000000000000000000000000000000000004827 246.0
HFD2_k127_6695699_21 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000003072 248.0
HFD2_k127_6695699_22 PFAM Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000001324 233.0
HFD2_k127_6695699_23 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000004408 229.0
HFD2_k127_6695699_24 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000004656 231.0
HFD2_k127_6695699_25 Cys-tRNA(Pro) hydrolase activity K03976,K19055 - - 0.00000000000000000000000000000000000000000000000000000008644 202.0
HFD2_k127_6695699_26 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000002608 169.0
HFD2_k127_6695699_27 Cold shock protein domain K03704 - - 0.0000000000000000000000000001421 121.0
HFD2_k127_6695699_28 Putative restriction endonuclease - - - 0.0000000000000000000000000003156 121.0
HFD2_k127_6695699_29 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000003222 123.0
HFD2_k127_6695699_3 Malate synthase K01638 - 2.3.3.9 6.06e-234 743.0
HFD2_k127_6695699_30 DNA methylase K07316 - 2.1.1.72 0.000000000000000001413 90.0
HFD2_k127_6695699_31 Polymer-forming cytoskeletal - - - 0.000000000000000003107 93.0
HFD2_k127_6695699_32 - - - - 0.0000000000000001566 87.0
HFD2_k127_6695699_33 - - - - 0.00000000000005611 84.0
HFD2_k127_6695699_34 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000009961 64.0
HFD2_k127_6695699_35 MlaD protein K02067 - - 0.000000003883 70.0
HFD2_k127_6695699_36 acyl carrier protein - - - 0.0000000118 59.0
HFD2_k127_6695699_37 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000001953 64.0
HFD2_k127_6695699_38 zinc ion binding - - - 0.0000006433 61.0
HFD2_k127_6695699_39 Peptidase family M50 K11749 - - 0.000155 54.0
HFD2_k127_6695699_4 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 606.0
HFD2_k127_6695699_5 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 599.0
HFD2_k127_6695699_6 Isocitrate lyase K01637 - 4.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 598.0
HFD2_k127_6695699_7 Cytochrome bd-type quinol oxidase subunit 1 K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 591.0
HFD2_k127_6695699_8 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007732 583.0
HFD2_k127_6695699_9 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 566.0
HFD2_k127_6739997_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.655e-203 662.0
HFD2_k127_6739997_1 nitrite transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 402.0
HFD2_k127_6739997_2 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 389.0
HFD2_k127_6739997_3 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 336.0
HFD2_k127_6739997_4 Competence protein K02238 - - 0.0000000000000000000000000000000000009883 147.0
HFD2_k127_6762453_0 Transposase IS66 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 473.0
HFD2_k127_6762453_1 helix_turn_helix, Lux Regulon - - - 0.000008774 50.0
HFD2_k127_6821123_0 Tricorn protease homolog K08676 - - 0.0 1470.0
HFD2_k127_6821123_1 Zinc carboxypeptidase K14054 - - 0.0 1052.0
HFD2_k127_6821123_2 AhpC/TSA family - - - 0.0000000000000000000000000000000000000000000000000000000000002246 232.0
HFD2_k127_6821123_3 - - - - 0.0000000000000000000000000007248 120.0
HFD2_k127_6821123_4 Protein of unknown function (DUF1684) K09164 - - 0.00000000000002199 83.0
HFD2_k127_6821123_5 Transposase IS200 like - - - 0.0000000000003333 74.0
HFD2_k127_6821123_6 amine dehydrogenase activity - - - 0.00003041 56.0
HFD2_k127_6827885_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 430.0
HFD2_k127_6827885_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008528 405.0
HFD2_k127_6827885_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 377.0
HFD2_k127_6827885_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 365.0
HFD2_k127_6827885_4 DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000007059 253.0
HFD2_k127_6827885_5 HIT domain K02503 - - 0.0000000000000000000000000000000000000001718 158.0
HFD2_k127_6827885_6 Ribosomal protein S21 K02970 - - 0.00000000000000000000003287 99.0
HFD2_k127_6844086_0 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 7.774e-310 969.0
HFD2_k127_6844086_1 Surface antigen K07277 - - 2.629e-208 673.0
HFD2_k127_6844086_10 UvrB/uvrC motif K19411 - - 0.0000000000000000000000000000000000000006285 164.0
HFD2_k127_6844086_11 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000347 153.0
HFD2_k127_6844086_12 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000003497 151.0
HFD2_k127_6844086_13 - - - - 0.0000000000000000000000000002254 117.0
HFD2_k127_6844086_14 - - - - 0.00000000009772 74.0
HFD2_k127_6844086_15 Outer membrane protein (OmpH-like) K06142 - - 0.00000003963 62.0
HFD2_k127_6844086_2 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 526.0
HFD2_k127_6844086_3 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 457.0
HFD2_k127_6844086_4 ATP:guanido phosphotransferase, C-terminal catalytic domain K19405 - 2.7.14.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 448.0
HFD2_k127_6844086_5 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008405 404.0
HFD2_k127_6844086_6 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000629 264.0
HFD2_k127_6844086_7 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000006547 264.0
HFD2_k127_6844086_8 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001459 263.0
HFD2_k127_6844086_9 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000157 257.0
HFD2_k127_6908185_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 422.0
HFD2_k127_6908185_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 385.0
HFD2_k127_6908185_2 Protein of unknown function (DUF541) K09797 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007961 258.0
HFD2_k127_6908185_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000001093 224.0
HFD2_k127_6908185_4 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000006837 143.0
HFD2_k127_6908185_5 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000001001 132.0
HFD2_k127_6908185_6 1,4-alpha-glucan branching enzyme activity K00700 - 2.4.1.18 0.0000000000000003288 88.0
HFD2_k127_6908185_7 Domain of unknown function (DUF4382) - - - 0.000000000001949 80.0
HFD2_k127_6908185_8 PFAM glycoside hydrolase, family 13 domain protein - - - 0.000000257 62.0
HFD2_k127_6908185_9 - - - - 0.00001926 56.0
HFD2_k127_6928297_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 1.013e-239 767.0
HFD2_k127_6928297_1 P2 response regulator binding domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 475.0
HFD2_k127_6928297_10 Tetratricopeptide repeat - - - 0.000006992 58.0
HFD2_k127_6928297_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 434.0
HFD2_k127_6928297_3 CheC-like family K03410 - - 0.0000000000000000000000000000000000000000000000000000000000000000009871 235.0
HFD2_k127_6928297_4 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000006282 233.0
HFD2_k127_6928297_5 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000000000000000000000005885 213.0
HFD2_k127_6928297_6 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000000000000000000000000000000000000000000104 203.0
HFD2_k127_6928297_7 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000009404 164.0
HFD2_k127_6928297_8 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000001163 149.0
HFD2_k127_6928297_9 PFAM CheW domain protein K03408 - - 0.000000000003039 75.0
HFD2_k127_6963589_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 570.0
HFD2_k127_699722_0 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 465.0
HFD2_k127_699722_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 365.0
HFD2_k127_699722_2 Histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000006369 153.0
HFD2_k127_699722_3 Thioesterase superfamily - - - 0.00000000000000000021 93.0
HFD2_k127_699722_4 Outer membrane protein beta-barrel domain - - - 0.000005975 57.0
HFD2_k127_699722_5 Outer membrane protein beta-barrel domain - - - 0.0006382 49.0
HFD2_k127_7034016_0 ABC transporter - - - 1.9e-248 777.0
HFD2_k127_7034016_1 Lysylphosphatidylglycerol synthase TM region K07027,K14205 - 2.3.2.3 8.838e-246 788.0
HFD2_k127_7034016_2 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 429.0
HFD2_k127_7034016_3 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003553 276.0
HFD2_k127_7034016_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000108 184.0
HFD2_k127_7034016_5 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000009912 147.0
HFD2_k127_7034016_6 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000005066 132.0
HFD2_k127_7034016_7 acyl carrier - - - 0.00000000188 63.0
HFD2_k127_7034016_8 Lipid A biosynthesis K02517 - 2.3.1.241 0.00001384 57.0
HFD2_k127_7034016_9 Heavy-metal-associated domain - - - 0.0003012 51.0
HFD2_k127_7050368_0 Histidine kinase HAMP K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 403.0
HFD2_k127_7050368_1 Oxidoreductase NAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008095 313.0
HFD2_k127_7050368_10 cheY-homologous receiver domain K07658 - - 0.0000000000000000000001259 102.0
HFD2_k127_7050368_11 Belongs to the UPF0434 family K09791 - - 0.0000000000000001001 82.0
HFD2_k127_7050368_2 4Fe-4S dicluster domain K17996 - 1.12.98.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 305.0
HFD2_k127_7050368_3 Belongs to the NiFe NiFeSe hydrogenase large subunit family K14126,K17993 GO:0003674,GO:0005488,GO:0005575,GO:0016151,GO:0032991,GO:0043167,GO:0043169,GO:0044569,GO:0046872,GO:0046914,GO:1902494 1.12.1.3,1.12.1.5,1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000762 302.0
HFD2_k127_7050368_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003478 263.0
HFD2_k127_7050368_5 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000002656 231.0
HFD2_k127_7050368_6 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000003322 236.0
HFD2_k127_7050368_7 NADH ubiquinone oxidoreductase 20 kDa subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000005926 206.0
HFD2_k127_7050368_8 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism - - - 0.00000000000000000000000000000000000005015 155.0
HFD2_k127_7050368_9 PFAM response regulator receiver - - - 0.000000000000000000000004617 107.0
HFD2_k127_70635_0 Belongs to the 'phage' integrase family K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000006729 230.0
HFD2_k127_7067813_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 570.0
HFD2_k127_7067813_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 551.0
HFD2_k127_7067813_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 478.0
HFD2_k127_7067813_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 435.0
HFD2_k127_7067813_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 298.0
HFD2_k127_7067813_5 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000002275 243.0
HFD2_k127_7067813_6 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000000000000000000000001048 168.0
HFD2_k127_7067813_7 Histidine biosynthesis protein K01814,K01817 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16,5.3.1.24 0.0000000000000000000000000009844 122.0
HFD2_k127_7067813_8 Cell division protein FtsQ K03589 - - 0.0001671 49.0
HFD2_k127_7073566_0 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 473.0
HFD2_k127_7073566_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000005354 274.0
HFD2_k127_7073566_2 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000000001716 136.0
HFD2_k127_7073566_3 - - - - 0.00000000000000000000000000000000889 147.0
HFD2_k127_7073566_4 MazG nucleotide pyrophosphohydrolase domain K02428 - 3.6.1.66 0.00000000000000000000000008463 111.0
HFD2_k127_7073566_5 Uncharacterized protein family UPF0004 K18707 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.000000000000000000000002556 110.0
HFD2_k127_7073566_6 - - - - 0.0000000000000001797 92.0
HFD2_k127_7073805_0 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000801 387.0
HFD2_k127_7073805_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 362.0
HFD2_k127_7073805_2 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 376.0
HFD2_k127_7073805_3 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001478 287.0
HFD2_k127_7073805_4 Peptidase family S58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007222 276.0
HFD2_k127_7073805_5 Diacylglycerol kinase catalytic domain (presumed) K07029 - 2.7.1.107 0.00000000000000000000000000000000000003484 165.0
HFD2_k127_7116486_0 heme-copper terminal oxidase activity K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 590.0
HFD2_k127_7116486_1 PFAM FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 363.0
HFD2_k127_7116486_10 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000006407 165.0
HFD2_k127_7116486_11 - - - - 0.000000000000000000000000000000000244 143.0
HFD2_k127_7116486_12 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000001227 145.0
HFD2_k127_7116486_13 Protein of unknown function (DUF3175) - - - 0.00000000000000000000000000001962 119.0
HFD2_k127_7116486_14 TIGRFAM Transcriptional regulator, Rrf2 - - - 0.000000000000000000000002779 107.0
HFD2_k127_7116486_15 polysaccharide deacetylase - - - 0.000000000000000000002526 96.0
HFD2_k127_7116486_16 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000002382 69.0
HFD2_k127_7116486_17 SCO1/SenC - - - 0.000000001287 69.0
HFD2_k127_7116486_18 Domain of unknown function (DUF4340) - - - 0.0000003927 62.0
HFD2_k127_7116486_19 Calcineurin-like phosphoesterase - - - 0.00003964 56.0
HFD2_k127_7116486_2 TIGRFAM Gliding motility-associated ABC transporter ATP-binding subunit GldA K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 294.0
HFD2_k127_7116486_3 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003624 281.0
HFD2_k127_7116486_4 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001748 273.0
HFD2_k127_7116486_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000007556 223.0
HFD2_k127_7116486_6 cytochrome c oxidase (Subunit II) - - - 0.000000000000000000000000000000000000000000000000000000001815 212.0
HFD2_k127_7116486_7 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000000000000001944 228.0
HFD2_k127_7116486_8 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000001232 227.0
HFD2_k127_7116486_9 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000004264 200.0
HFD2_k127_7173217_0 DNA ligase (ATP) activity K01971 - 6.5.1.1 3.455e-303 951.0
HFD2_k127_7173217_1 Putative glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 596.0
HFD2_k127_7173217_10 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000003365 221.0
HFD2_k127_7173217_11 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000006341 207.0
HFD2_k127_7173217_12 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000002388 191.0
HFD2_k127_7173217_13 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000006351 135.0
HFD2_k127_7173217_14 DNA recombination K03497,K13582 - - 0.0000000000000000000000334 113.0
HFD2_k127_7173217_15 Protein of unknown function (DUF3494) - - - 0.000000000000002405 84.0
HFD2_k127_7173217_16 response to copper ion K02388,K02396 - - 0.0000000002795 68.0
HFD2_k127_7173217_17 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00002102 54.0
HFD2_k127_7173217_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 558.0
HFD2_k127_7173217_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 481.0
HFD2_k127_7173217_4 Aerotolerance regulator N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 316.0
HFD2_k127_7173217_5 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000587 295.0
HFD2_k127_7173217_6 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 291.0
HFD2_k127_7173217_7 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005799 303.0
HFD2_k127_7173217_8 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006558 274.0
HFD2_k127_7173217_9 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005032 258.0
HFD2_k127_726052_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000819 473.0
HFD2_k127_726052_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 431.0
HFD2_k127_726052_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 422.0
HFD2_k127_726052_3 Cell cycle protein K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 303.0
HFD2_k127_726052_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000862 307.0
HFD2_k127_726052_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000002841 147.0
HFD2_k127_726052_6 Cell division protein FtsI penicillin-binding protein 2 K03587 - 3.4.16.4 0.0006148 46.0
HFD2_k127_7272244_0 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 363.0
HFD2_k127_7272244_1 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000002049 161.0
HFD2_k127_7272244_2 COG COG0436 Aspartate tyrosine aromatic aminotransferase K10907 - - 0.0000000000000000000000001064 111.0
HFD2_k127_7281359_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 2.121e-275 863.0
HFD2_k127_7281359_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 3.81e-242 764.0
HFD2_k127_7281359_10 Domain of unknown function (DUF3536) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 511.0
HFD2_k127_7281359_11 PFAM Glycosyl transferase family 2 K00786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 459.0
HFD2_k127_7281359_12 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 460.0
HFD2_k127_7281359_13 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005571 422.0
HFD2_k127_7281359_14 esterase of the alpha-beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 374.0
HFD2_k127_7281359_15 Belongs to the glycosyl hydrolase 57 family K03406,K16149 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 407.0
HFD2_k127_7281359_16 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 359.0
HFD2_k127_7281359_17 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 355.0
HFD2_k127_7281359_18 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 332.0
HFD2_k127_7281359_19 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 334.0
HFD2_k127_7281359_2 hydroxymethylglutaryl-CoA reductase (NADPH) activity K00021 - 1.1.1.34 1.613e-225 712.0
HFD2_k127_7281359_20 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 303.0
HFD2_k127_7281359_21 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000005043 254.0
HFD2_k127_7281359_22 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000000000000000008683 219.0
HFD2_k127_7281359_23 anion-transporting ATPase - - - 0.00000000000000000000000000000000000000000000000000000000004563 226.0
HFD2_k127_7281359_24 PFAM Squalene phytoene synthase K00801 - 2.5.1.21 0.0000000000000000000000000000000000000000000000000000000002079 209.0
HFD2_k127_7281359_25 Formamidopyrimidine-DNA glycosylase N-terminal domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000001424 164.0
HFD2_k127_7281359_26 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000009917 167.0
HFD2_k127_7281359_27 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000005959 140.0
HFD2_k127_7281359_28 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000002088 137.0
HFD2_k127_7281359_29 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000001886 114.0
HFD2_k127_7281359_3 cytochrome C peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 544.0
HFD2_k127_7281359_30 HEAT repeats - - - 0.00000000000000004554 94.0
HFD2_k127_7281359_31 PHB/PHA accumulation regulator DNA-binding domain - - - 0.000000000000001048 83.0
HFD2_k127_7281359_32 granule-associated protein - - - 0.00000000000001411 78.0
HFD2_k127_7281359_33 Tetratricopeptide repeat - - - 0.00000000208 70.0
HFD2_k127_7281359_35 response regulator K07666 GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010035,GO:0010038,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.000001692 56.0
HFD2_k127_7281359_4 TIGRFAM amidase, hydantoinase carbamoylase family K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006255 512.0
HFD2_k127_7281359_5 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 528.0
HFD2_k127_7281359_6 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 512.0
HFD2_k127_7281359_7 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 526.0
HFD2_k127_7281359_8 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 511.0
HFD2_k127_7281359_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 483.0
HFD2_k127_7281556_0 Glycosyl transferase 4-like K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 437.0
HFD2_k127_7281556_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 296.0
HFD2_k127_7281556_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000009632 261.0
HFD2_k127_7281556_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000001835 227.0
HFD2_k127_7281556_4 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000000000000000005988 125.0
HFD2_k127_7319694_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000004191 231.0
HFD2_k127_7319694_1 integral membrane protein K07027 - - 0.000000000000000003959 96.0
HFD2_k127_7319694_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000005444 78.0
HFD2_k127_7321082_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 6.553e-198 622.0
HFD2_k127_7321082_1 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 443.0
HFD2_k127_7321082_2 Enoyl-(Acyl carrier protein) reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000004726 224.0
HFD2_k127_7321082_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000002837 222.0
HFD2_k127_7321082_4 EVE domain - - - 0.000000000000000000000000000000000000000000000000000002124 196.0
HFD2_k127_7321082_5 Enoyl-CoA hydratase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000005629 182.0
HFD2_k127_7321082_6 DinB family - - - 0.000000000000000000000000000000000000000002314 162.0
HFD2_k127_7321082_7 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000001235 145.0
HFD2_k127_7331326_0 Glutamate formimidoyltransferase K00603,K13990 - 2.1.2.5,4.3.1.4 3.751e-220 697.0
HFD2_k127_7331326_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 586.0
HFD2_k127_7331326_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 296.0
HFD2_k127_7331326_11 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005296 296.0
HFD2_k127_7331326_12 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000022 295.0
HFD2_k127_7331326_13 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00090 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000001786 264.0
HFD2_k127_7331326_14 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000002232 245.0
HFD2_k127_7331326_15 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001613 245.0
HFD2_k127_7331326_16 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000003826 233.0
HFD2_k127_7331326_17 S4 RNA-binding domain K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000008515 240.0
HFD2_k127_7331326_18 von Willebrand factor type A domain K07114 - - 0.0000000000000000000000000000000000000000001699 180.0
HFD2_k127_7331326_19 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000004542 139.0
HFD2_k127_7331326_2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 522.0
HFD2_k127_7331326_20 Histidine kinase - - - 0.000000000000000000000000000000001875 139.0
HFD2_k127_7331326_21 response regulator - - - 0.00000000000000000000000000003634 127.0
HFD2_k127_7331326_22 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000009635 123.0
HFD2_k127_7331326_23 nitric oxide dioxygenase activity - - - 0.0000000000000000000008324 100.0
HFD2_k127_7331326_24 Zinc finger domain - - - 0.0000000000000053 85.0
HFD2_k127_7331326_25 Putative phosphatase (DUF442) - - - 0.00000000000001519 81.0
HFD2_k127_7331326_26 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000006114 69.0
HFD2_k127_7331326_27 domain protein K13735 - - 0.0000000004496 73.0
HFD2_k127_7331326_28 Bacterial Ig-like domain 2 - - - 0.0000004612 63.0
HFD2_k127_7331326_29 - - - - 0.00000171 59.0
HFD2_k127_7331326_3 Aldo/keto reductase family K19265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 491.0
HFD2_k127_7331326_30 - - - - 0.000006996 57.0
HFD2_k127_7331326_31 - - - - 0.00002946 51.0
HFD2_k127_7331326_4 Polysaccharide biosynthesis protein K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 499.0
HFD2_k127_7331326_5 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 466.0
HFD2_k127_7331326_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 368.0
HFD2_k127_7331326_8 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 359.0
HFD2_k127_7331326_9 Protein of unknown function (DUF1194) K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 348.0
HFD2_k127_7360867_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.226e-250 781.0
HFD2_k127_7360867_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 427.0
HFD2_k127_7360867_2 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000009488 188.0
HFD2_k127_7360867_3 Cytochrome c - - - 0.000000000000000000000000004199 126.0
HFD2_k127_7372537_0 Prolyl oligopeptidase family - - - 9.67e-262 839.0
HFD2_k127_7372537_1 Protein of unknown function (DUF3500) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 484.0
HFD2_k127_7372537_10 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0002964 54.0
HFD2_k127_7372537_2 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 331.0
HFD2_k127_7372537_3 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 317.0
HFD2_k127_7372537_4 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000008347 188.0
HFD2_k127_7372537_5 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000003046 192.0
HFD2_k127_7372537_6 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.00000000000000000000000000000000000006387 148.0
HFD2_k127_7372537_7 Domain of unknown function DUF11 - - - 0.000000000000000000000000000000000027 156.0
HFD2_k127_7372537_8 metallocarboxypeptidase activity K14054 - - 0.00000000000000000000000004343 108.0
HFD2_k127_7372537_9 - - - - 0.00000005765 59.0
HFD2_k127_7396932_0 beta-galactosidase activity - - - 0.0 1409.0
HFD2_k127_7396932_1 Glucodextranase, domain N K01178 - 3.2.1.3 0.0 1068.0
HFD2_k127_7396932_10 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002424 276.0
HFD2_k127_7396932_11 PFAM helix-turn-helix domain protein - - - 0.000000000000000000000000000000000000000000004465 166.0
HFD2_k127_7396932_12 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000002093 168.0
HFD2_k127_7396932_13 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000007684 117.0
HFD2_k127_7396932_14 Domain of unknown function (DUF4440) - - - 0.000003245 61.0
HFD2_k127_7396932_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.92e-239 751.0
HFD2_k127_7396932_3 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 632.0
HFD2_k127_7396932_4 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000872 484.0
HFD2_k127_7396932_5 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005367 487.0
HFD2_k127_7396932_6 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 454.0
HFD2_k127_7396932_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 377.0
HFD2_k127_7396932_8 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009805 314.0
HFD2_k127_7396932_9 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002379 290.0
HFD2_k127_7450768_0 Amidohydrolase family - - - 1.43e-217 691.0
HFD2_k127_7450768_1 protein kinase activity - - - 8.085e-200 655.0
HFD2_k127_7450768_2 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 424.0
HFD2_k127_7450768_3 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004931 359.0
HFD2_k127_7450768_4 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 311.0
HFD2_k127_7450768_5 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001254 289.0
HFD2_k127_7450768_6 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000002799 273.0
HFD2_k127_7450768_7 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000005904 136.0
HFD2_k127_7450768_8 - - - - 0.00000000000000000000001846 104.0
HFD2_k127_7452104_0 metal-dependent phosphohydrolase, HD sub domain K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 412.0
HFD2_k127_7452104_1 CYTH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 316.0
HFD2_k127_7452104_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000001604 177.0
HFD2_k127_7532300_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 8.604e-273 853.0
HFD2_k127_7532300_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 332.0
HFD2_k127_7532300_10 Regulator of chromosome condensation (RCC1) repeat - - - 0.000000006175 67.0
HFD2_k127_7532300_11 response to antibiotic - - - 0.0001328 53.0
HFD2_k127_7532300_12 cellulase activity - - - 0.0003295 52.0
HFD2_k127_7532300_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006543 282.0
HFD2_k127_7532300_3 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000256 268.0
HFD2_k127_7532300_4 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000006324 246.0
HFD2_k127_7532300_5 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K00950,K01633 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000000000000000000000000000000392 269.0
HFD2_k127_7532300_6 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000009126 175.0
HFD2_k127_7532300_7 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000006071 154.0
HFD2_k127_7532300_8 Putative lumazine-binding - - - 0.000000000000000000000000001263 127.0
HFD2_k127_7532300_9 Protein of unknown function (DUF2723) - - - 0.0000000000000000001113 102.0
HFD2_k127_753259_0 TonB-dependent Receptor Plug Domain K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 445.0
HFD2_k127_753259_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 429.0
HFD2_k127_753259_10 Surface antigen K07277,K07278 - - 0.0001782 52.0
HFD2_k127_753259_2 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 402.0
HFD2_k127_753259_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07032 - - 0.000000000000000000000000000000000000000000000000000001187 207.0
HFD2_k127_753259_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000794 199.0
HFD2_k127_753259_5 Cupin domain - - - 0.00000000000000000000000000000000000000000000000005482 181.0
HFD2_k127_753259_6 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000001541 154.0
HFD2_k127_753259_7 Wd40 repeat-containing protein - - - 0.0000000000000009076 93.0
HFD2_k127_753259_9 - - - - 0.00001335 55.0
HFD2_k127_7542055_0 Tricorn protease C1 domain K08676 - - 0.0 1091.0
HFD2_k127_7542055_1 Multicopper oxidase K04753,K08100 - 1.3.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 349.0
HFD2_k127_7542055_10 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.00000000002564 69.0
HFD2_k127_7542055_11 - - - - 0.00003554 49.0
HFD2_k127_7542055_2 Sodium:alanine symporter family K03310 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002401 270.0
HFD2_k127_7542055_3 amino acid carrier protein K03310 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008678 245.0
HFD2_k127_7542055_4 Cytochrome c K00376,K02305,K17760 - 1.1.9.1,1.7.2.4 0.00000000000000000000000000000000000000000000000006123 193.0
HFD2_k127_7542055_5 - - - - 0.000000000000000000000000000000000000000000544 162.0
HFD2_k127_7542055_7 FAD binding domain - - - 0.0000000000000000000000000000001113 129.0
HFD2_k127_7542055_8 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045926,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000002214 103.0
HFD2_k127_7542055_9 Cytochrome c - - - 0.000000000005774 78.0
HFD2_k127_7547340_0 Pfam Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000004298 142.0
HFD2_k127_7547340_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000007242 87.0
HFD2_k127_7574173_0 PglZ domain - - - 2.889e-194 619.0
HFD2_k127_7574173_1 ABC transporter transmembrane region K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 411.0
HFD2_k127_7574173_2 4Fe-4S single cluster domain K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005845 256.0
HFD2_k127_7574173_3 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000003062 198.0
HFD2_k127_7609399_0 serine-type peptidase activity K01303 - 3.4.19.1 4.784e-264 827.0
HFD2_k127_7609399_1 PFAM multicopper oxidase type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 410.0
HFD2_k127_7609399_10 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.000000000000000000000000000000000000000000000000000000000000000006946 232.0
HFD2_k127_7609399_11 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.000000000000000000000000000000000000000000000000002263 192.0
HFD2_k127_7609399_12 SdpI/YhfL protein family - GO:0008150,GO:0009636,GO:0042221,GO:0050896 - 0.000000000000000000000000000000000000000000000000005806 190.0
HFD2_k127_7609399_13 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000000000000000000002882 170.0
HFD2_k127_7609399_14 alpha beta K06889 - - 0.00000000000000000000000000000000000000000002558 180.0
HFD2_k127_7609399_15 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000104 162.0
HFD2_k127_7609399_16 nucleoside hydrolase K01250 - - 0.000000000000000000000000000000000000001614 158.0
HFD2_k127_7609399_17 NUDIX domain - - - 0.00000000000000000000000000000000000001817 152.0
HFD2_k127_7609399_18 3-hydroxyacyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000003939 159.0
HFD2_k127_7609399_19 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.0000000000000000000000000000000001811 138.0
HFD2_k127_7609399_2 DNA restriction-modification system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 408.0
HFD2_k127_7609399_20 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000001925 102.0
HFD2_k127_7609399_21 helicase - - - 0.0000000000000003455 93.0
HFD2_k127_7609399_23 Endonuclease Exonuclease Phosphatase - - - 0.000000000006553 78.0
HFD2_k127_7609399_24 SnoaL-like domain - - - 0.0000001552 59.0
HFD2_k127_7609399_25 Protein of unknown function (DUF402) - - - 0.000002625 60.0
HFD2_k127_7609399_26 DNA polymerase involved in DNA repair K14161 - - 0.00001403 53.0
HFD2_k127_7609399_3 transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008886 374.0
HFD2_k127_7609399_4 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 340.0
HFD2_k127_7609399_5 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 306.0
HFD2_k127_7609399_6 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006668 295.0
HFD2_k127_7609399_7 Beta-lactamase class A K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000014 285.0
HFD2_k127_7609399_8 ABC-type tungstate transport system permease component-like protein K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000008366 244.0
HFD2_k127_7609399_9 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000003549 242.0
HFD2_k127_7622784_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009999 471.0
HFD2_k127_7622784_1 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 365.0
HFD2_k127_7650594_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 593.0
HFD2_k127_7650594_1 Belongs to the serpin family K13963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 324.0
HFD2_k127_7650594_10 - - - - 0.000000001515 67.0
HFD2_k127_7650594_12 Dehydrogenase E1 component K00164 - 1.2.4.2 0.0002478 46.0
HFD2_k127_7650594_2 Lytic transglycosylase catalytic K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002445 293.0
HFD2_k127_7650594_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000000005143 238.0
HFD2_k127_7650594_4 amino acid aldolase or racemase K20757 - 4.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000009159 239.0
HFD2_k127_7650594_5 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000923 212.0
HFD2_k127_7650594_6 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000003881 187.0
HFD2_k127_7650594_7 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000001323 168.0
HFD2_k127_7650594_8 SWI complex, BAF60b domains - - - 0.00000000000000000000000000003679 124.0
HFD2_k127_7650594_9 - - - - 0.00000000001109 74.0
HFD2_k127_7651895_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 484.0
HFD2_k127_7651895_1 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000008522 78.0
HFD2_k127_7651895_2 GHMP kinase - - - 0.0008195 42.0
HFD2_k127_7663004_0 PFAM amino acid permease-associated region K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 545.0
HFD2_k127_7663004_1 Cytochrome oxidase assembly protein K02259 - - 0.000000000000000000000000000000000000003224 169.0
HFD2_k127_7663004_2 amino acid activation for nonribosomal peptide biosynthetic process K05996 - 3.4.17.18 0.0000000000000000000000000000000001163 154.0
HFD2_k127_7729097_0 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004758 287.0
HFD2_k127_7729097_1 Arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000001315 261.0
HFD2_k127_7729097_2 Belongs to the PdaD family K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000004388 232.0
HFD2_k127_7729097_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000007483 178.0
HFD2_k127_7729097_4 Ferric uptake regulator family K03711 - - 0.00000000000000000000000000000000000000000000002662 176.0
HFD2_k127_7729097_5 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000001884 160.0
HFD2_k127_7729097_6 Periplasmic or secreted lipoprotein - - - 0.0000003583 61.0
HFD2_k127_7729097_7 - - - - 0.0006157 48.0
HFD2_k127_7746221_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 621.0
HFD2_k127_7746221_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 481.0
HFD2_k127_7746221_10 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000001605 114.0
HFD2_k127_7746221_11 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000009761 98.0
HFD2_k127_7746221_12 - - - - 0.00000001525 66.0
HFD2_k127_7746221_2 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 422.0
HFD2_k127_7746221_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 402.0
HFD2_k127_7746221_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 316.0
HFD2_k127_7746221_5 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001117 274.0
HFD2_k127_7746221_6 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000001487 221.0
HFD2_k127_7746221_7 HD superfamily hydrolase involved in NAD metabolism K00950 - 2.7.6.3 0.0000000000000000000000000000000006853 137.0
HFD2_k127_7746221_8 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000001057 125.0
HFD2_k127_7746221_9 HEAT repeats - - - 0.0000000000000000000000000001317 122.0
HFD2_k127_7793582_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 3.322e-282 898.0
HFD2_k127_7793582_1 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 1.426e-223 722.0
HFD2_k127_7793582_2 Alpha amylase, catalytic domain - - - 3.672e-195 644.0
HFD2_k127_7793582_3 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 422.0
HFD2_k127_7793582_4 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 346.0
HFD2_k127_7793582_5 Belongs to the glycosyl hydrolase 2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004965 250.0
HFD2_k127_7793582_6 enterobactin catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000002699 223.0
HFD2_k127_7793582_7 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000005378 159.0
HFD2_k127_780732_0 Tetrahydrodipicolinate N-succinyltransferase N-terminal K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 344.0
HFD2_k127_780732_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 313.0
HFD2_k127_780732_2 peptidase dimerisation domain K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000003611 191.0
HFD2_k127_780732_3 Belongs to the DapB family K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000007699 191.0
HFD2_k127_780732_4 PFAM aminotransferase, class I K10907 - - 0.0000000000000000000000000000000000002024 158.0
HFD2_k127_7840916_0 PQQ enzyme repeat K00117 - 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 599.0
HFD2_k127_7840916_1 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 563.0
HFD2_k127_7840916_2 Domain of unknown function (DUF2172) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 539.0
HFD2_k127_7840916_3 C-methyltransferase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007789 536.0
HFD2_k127_7840916_4 PFAM NAD dependent epimerase dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 437.0
HFD2_k127_7840916_5 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001494 301.0
HFD2_k127_7840916_6 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K11206,K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000301 247.0
HFD2_k127_7840916_7 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K00067,K01790 - 1.1.1.133,5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000001041 241.0
HFD2_k127_7840916_8 Polysaccharide pyruvyl transferase - - - 0.000000000000000000000000000000000000000000001448 182.0
HFD2_k127_7840916_9 Glycosyl transferases group 1 - - - 0.0000000000003217 77.0
HFD2_k127_7851598_0 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 554.0
HFD2_k127_7851598_1 DNA polymerase alpha chain like domain K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 494.0
HFD2_k127_7851598_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000003138 268.0
HFD2_k127_7851598_3 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000001001 237.0
HFD2_k127_7851598_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000001151 215.0
HFD2_k127_7851598_5 - - - - 0.000000000000006082 89.0
HFD2_k127_7906305_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 608.0
HFD2_k127_7906305_1 ABC transporter K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 381.0
HFD2_k127_7906305_2 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008499 354.0
HFD2_k127_7906305_3 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000008564 166.0
HFD2_k127_7906305_4 ABC-2 family transporter protein K01992 - - 0.0000000000000005618 82.0
HFD2_k127_7909999_0 Elongation factor G, domain IV K02355 - - 3.276e-269 845.0
HFD2_k127_7909999_1 Beta-L-arabinofuranosidase, GH127 - - - 6.179e-228 723.0
HFD2_k127_7909999_10 ATP-grasp domain K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 300.0
HFD2_k127_7909999_11 PFAM Squalene phytoene synthase K00801 - 2.5.1.21 0.00000000000000000000000000000000000000000000000000000000004491 223.0
HFD2_k127_7909999_12 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000001406 207.0
HFD2_k127_7909999_13 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000000006498 187.0
HFD2_k127_7909999_14 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000001814 175.0
HFD2_k127_7909999_15 - - - - 0.000000000000000000000000000000000001477 149.0
HFD2_k127_7909999_16 - - - - 0.0000000000000000000000000000003559 141.0
HFD2_k127_7909999_17 acetyltransferase K18815 - 2.3.1.82 0.0000000000000000000000000411 124.0
HFD2_k127_7909999_18 - - - - 0.00000000000000000000002182 115.0
HFD2_k127_7909999_19 dCMP deaminase activity K01493 - 3.5.4.12 0.00000000000000000002784 103.0
HFD2_k127_7909999_2 belongs to the thiolase family K07508,K17972 GO:0001666,GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006066,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006694,GO:0006695,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006839,GO:0006915,GO:0006950,GO:0006996,GO:0007005,GO:0007006,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008219,GO:0008610,GO:0008637,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009628,GO:0009966,GO:0009968,GO:0009987,GO:0010639,GO:0010646,GO:0010648,GO:0010821,GO:0010823,GO:0010941,GO:0012501,GO:0016042,GO:0016043,GO:0016054,GO:0016125,GO:0016126,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019637,GO:0019693,GO:0019752,GO:0023051,GO:0023057,GO:0030258,GO:0031974,GO:0032787,GO:0032879,GO:0033043,GO:0033554,GO:0033865,GO:0033875,GO:0034032,GO:0034440,GO:0034641,GO:0035383,GO:0035795,GO:0036293,GO:0036294,GO:0042221,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046165,GO:0046395,GO:0046483,GO:0046902,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051129,GO:0051179,GO:0051186,GO:0051234,GO:0051716,GO:0055086,GO:0055114,GO:0060548,GO:0061024,GO:0065007,GO:0065008,GO:0070013,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071704,GO:0071840,GO:0072329,GO:0072521,GO:0090559,GO:1901028,GO:1901029,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1902108,GO:1902109,GO:1902652,GO:1902653,GO:1905709,GO:2001233,GO:2001234 2.3.1.16,2.3.1.254 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005236 452.0
HFD2_k127_7909999_20 Predicted membrane protein (DUF2231) - - - 0.00000000000000000004802 97.0
HFD2_k127_7909999_3 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 450.0
HFD2_k127_7909999_4 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006452 439.0
HFD2_k127_7909999_5 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 362.0
HFD2_k127_7909999_6 Dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 348.0
HFD2_k127_7909999_7 FAD linked oxidases, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007015 359.0
HFD2_k127_7909999_8 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000846 305.0
HFD2_k127_7909999_9 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000178 290.0
HFD2_k127_7964718_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000006644 224.0
HFD2_k127_7964718_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000005427 203.0
HFD2_k127_7964718_2 Ferric reductase like transmembrane component - - - 0.0000000000000000000000000000000000002707 154.0
HFD2_k127_7964718_3 - K14340 - - 0.0000000000000000000000000000000000007223 157.0
HFD2_k127_7964718_4 domain protein K12516 - - 0.000000000000000000000009222 113.0
HFD2_k127_7964718_5 oxidoreductase - - - 0.00000000000000000000003614 112.0
HFD2_k127_7964718_6 Carboxypeptidase regulatory-like domain - - - 0.000002395 57.0
HFD2_k127_7974818_0 Atp-dependent helicase - - - 8.602e-310 970.0
HFD2_k127_7974818_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.36e-262 818.0
HFD2_k127_7974818_10 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000002923 230.0
HFD2_k127_7974818_11 - - - - 0.00000000000000000000000000000000000000000000000001447 196.0
HFD2_k127_7974818_12 gluconolactonase activity - - - 0.00000000000000000000000000000000001486 156.0
HFD2_k127_7974818_13 - - - - 0.0000000000000000000000000000005282 142.0
HFD2_k127_7974818_14 Thioesterase superfamily K07107 - - 0.00000000000000000000000001174 115.0
HFD2_k127_7974818_15 methyl-accepting chemotaxis protein - - - 0.00000000000000003219 96.0
HFD2_k127_7974818_16 Bacterial regulatory proteins, tetR family K09017 - - 0.0000000000002529 80.0
HFD2_k127_7974818_17 amine dehydrogenase activity - - - 0.00000000001074 77.0
HFD2_k127_7974818_19 Rdx family K07401 - - 0.000003686 51.0
HFD2_k127_7974818_2 Zinc carboxypeptidase - - - 1.061e-230 762.0
HFD2_k127_7974818_20 Propionate catabolism activator - - - 0.00001498 54.0
HFD2_k127_7974818_21 Sugar-specific transcriptional regulator TrmB - - - 0.00002112 55.0
HFD2_k127_7974818_22 Subtilase family - - - 0.0000531 56.0
HFD2_k127_7974818_3 3-isopropylmalate dehydratase activity K01681,K01703,K01704,K17749 - 4.2.1.3,4.2.1.33,4.2.1.35 7.598e-229 743.0
HFD2_k127_7974818_4 LytB protein K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 504.0
HFD2_k127_7974818_5 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 460.0
HFD2_k127_7974818_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648,K18003 - 2.3.1.180,2.3.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 391.0
HFD2_k127_7974818_7 Putative glycosyl hydrolase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005938 284.0
HFD2_k127_7974818_8 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003928 277.0
HFD2_k127_7974818_9 Peptidase dimerisation domain K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000001273 242.0
HFD2_k127_8015533_0 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009695 313.0
HFD2_k127_8038883_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 9.028e-267 844.0
HFD2_k127_8038883_1 Aromatic amino acid lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 535.0
HFD2_k127_8038883_2 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 471.0
HFD2_k127_8038883_3 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 394.0
HFD2_k127_8038883_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000004133 219.0
HFD2_k127_8038883_5 OmpA family K03640 - - 0.00000000000000000000000000000002015 132.0
HFD2_k127_8038883_6 Outer membrane lipoprotein - - - 0.0000000000000000000000000000003391 133.0
HFD2_k127_8038883_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000004577 137.0
HFD2_k127_8040978_0 Belongs to the ATP-dependent AMP-binding enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 448.0
HFD2_k127_8040978_1 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 436.0
HFD2_k127_8040978_10 Acyltransferase - - - 0.0003666 52.0
HFD2_k127_8040978_2 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007271 329.0
HFD2_k127_8040978_3 Tryptophan halogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000341 250.0
HFD2_k127_8040978_4 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000003475 193.0
HFD2_k127_8040978_5 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000001213 183.0
HFD2_k127_8040978_6 O-methyltransferase - - - 0.0000000000000000000000000000000001739 139.0
HFD2_k127_8040978_7 polysaccharide deacetylase - - - 0.0000000000000000000000000002693 132.0
HFD2_k127_8040978_8 acyl carrier protein - - - 0.0000000000001192 79.0
HFD2_k127_8040978_9 - - - - 0.00001289 53.0
HFD2_k127_8088211_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0 1149.0
HFD2_k127_8088211_1 Peptidase S46 - GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008239,GO:0009056,GO:0009279,GO:0009986,GO:0009987,GO:0016020,GO:0016049,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030154,GO:0030312,GO:0030313,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0040007,GO:0042277,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044462,GO:0044464,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048869,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 9.715e-230 733.0
HFD2_k127_8088211_2 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 464.0
HFD2_k127_8088211_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000655 283.0
HFD2_k127_8088211_4 competence protein - - - 0.000000000000000000000000000000000000000000000000000000000006138 214.0
HFD2_k127_8088211_6 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000002109 74.0
HFD2_k127_8088211_7 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045926,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.00000000002788 70.0
HFD2_k127_8088211_8 - - - - 0.00000000002851 77.0
HFD2_k127_8088211_9 protocatechuate 3,4-dioxygenase activity - - - 0.0000000102 69.0
HFD2_k127_8136528_0 PFAM Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004731 280.0
HFD2_k127_8136528_1 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000005757 181.0
HFD2_k127_8136528_2 VanZ like family - - - 0.00000000000000000000000000000000000000002876 168.0
HFD2_k127_8136528_3 ubiE/COQ5 methyltransferase family - - - 0.0000000004903 67.0
HFD2_k127_8155550_0 UDP binding domain K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 558.0
HFD2_k127_8155550_1 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 489.0
HFD2_k127_8155550_2 UDP binding domain K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 434.0
HFD2_k127_8165706_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 9.004e-231 724.0
HFD2_k127_8165706_1 O-acyltransferase activity K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002192 273.0
HFD2_k127_8165706_2 cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000001985 233.0
HFD2_k127_8214789_0 Domain of unknown function (DUF5118) - - - 3.925e-207 672.0
HFD2_k127_8214789_1 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007741 310.0
HFD2_k127_8214789_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004467 268.0
HFD2_k127_8214789_3 Predicted membrane protein (DUF2231) - - - 0.000000000000000000000000000000000000000000001924 170.0
HFD2_k127_8214789_4 Predicted membrane protein (DUF2214) K08983 - - 0.0000000000000000000000000000000000001721 146.0
HFD2_k127_8214789_5 aminopeptidase N - - - 0.000000000000000000000000000000000005281 141.0
HFD2_k127_8214789_6 Cold shock protein domain K03704 - - 0.00000000000000000000000000000001129 127.0
HFD2_k127_8214789_7 Domain of unknown function (DUF4382) - - - 0.0002112 52.0
HFD2_k127_8235424_0 TonB dependent receptor K02014 - - 1.422e-205 676.0
HFD2_k127_8235424_1 - - - - 0.00000000000000000000002722 104.0
HFD2_k127_8235424_2 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000006496 64.0
HFD2_k127_8263140_0 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 341.0
HFD2_k127_8277203_0 Sortilin, neurotensin receptor 3, - - - 0.0 1274.0
HFD2_k127_8277203_1 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 478.0
HFD2_k127_8277203_10 LemA family K03744 - - 0.000000000000000000000000000000000000000000000002156 181.0
HFD2_k127_8277203_11 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000006028 176.0
HFD2_k127_8277203_12 DinB family - - - 0.00000000000000000000000000000000000000000008238 179.0
HFD2_k127_8277203_13 Putative capsular polysaccharide synthesis protein - - - 0.0000000000000000000000000000000000002972 159.0
HFD2_k127_8277203_14 Protein of unknown function (DUF3014) - - - 0.0000000000000000000000000000000000005357 147.0
HFD2_k127_8277203_15 Sulfotransferase K01014,K01016,K01025 - 2.8.2.1,2.8.2.4 0.00000000000000000000000000003329 130.0
HFD2_k127_8277203_16 HAD-hyrolase-like - - - 0.0000000000000000000000000008664 126.0
HFD2_k127_8277203_17 TIGRFAM hopanoid biosynthesis associated glycosyl transferase protein HpnI K00720 - 2.4.1.80 0.0000000000000000000004037 109.0
HFD2_k127_8277203_18 SNARE associated Golgi protein - - - 0.0000000000000244 78.0
HFD2_k127_8277203_19 DoxX - - - 0.00008471 54.0
HFD2_k127_8277203_2 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 359.0
HFD2_k127_8277203_3 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 342.0
HFD2_k127_8277203_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 327.0
HFD2_k127_8277203_5 PFAM Lytic transglycosylase-like, catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001423 262.0
HFD2_k127_8277203_6 competence protein COMEC - - - 0.000000000000000000000000000000000000000000000000000000000000000004737 250.0
HFD2_k127_8277203_7 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000001133 221.0
HFD2_k127_8277203_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000001279 236.0
HFD2_k127_8277203_9 RNA repair, ligase-Pnkp-associating, region of Hen1 - - - 0.00000000000000000000000000000000000000000000000009611 186.0
HFD2_k127_8311259_0 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 290.0
HFD2_k127_8311259_1 Thioredoxin-like domain K03671 - - 0.00000000000000000000000000000000000000335 150.0
HFD2_k127_8311259_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.00000000000000000000000000000000000009929 153.0
HFD2_k127_8311259_3 - - - - 0.00000000000000002028 88.0
HFD2_k127_8311259_4 - - - - 0.00000001085 64.0
HFD2_k127_8326991_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 4.405e-304 958.0
HFD2_k127_8326991_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007217 563.0
HFD2_k127_8326991_10 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000001572 108.0
HFD2_k127_8326991_11 Cold shock K03704 GO:0001072,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003723,GO:0003727,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008143,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043242,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051087,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0060567,GO:0065007,GO:0070717,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000001905 90.0
HFD2_k127_8326991_12 - - - - 0.000000000000000461 84.0
HFD2_k127_8326991_13 PFAM PQQ enzyme repeat - - - 0.000000000000003284 89.0
HFD2_k127_8326991_14 Ribosomal protein L34 K02914 - - 0.00000000000001408 74.0
HFD2_k127_8326991_15 - - - - 0.00003106 49.0
HFD2_k127_8326991_16 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.0002602 51.0
HFD2_k127_8326991_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 552.0
HFD2_k127_8326991_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005243 396.0
HFD2_k127_8326991_4 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 331.0
HFD2_k127_8326991_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000007805 243.0
HFD2_k127_8326991_6 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000004023 218.0
HFD2_k127_8326991_7 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000001392 204.0
HFD2_k127_8326991_8 Tetratricopeptide repeat K08309 - - 0.0000000000000000000000000000000002681 153.0
HFD2_k127_8326991_9 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000001029 125.0
HFD2_k127_8342728_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1127.0
HFD2_k127_8342728_1 lysine biosynthetic process via aminoadipic acid - - - 2.766e-243 780.0
HFD2_k127_8342728_2 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 411.0
HFD2_k127_8342728_3 PFAM outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000002866 240.0
HFD2_k127_8342728_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000001767 193.0
HFD2_k127_8342728_5 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000001547 144.0
HFD2_k127_8342728_7 WHG domain - - - 0.00001004 51.0
HFD2_k127_8345112_0 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 359.0
HFD2_k127_8345112_1 Domain of unknown function (DUF305) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004324 245.0
HFD2_k127_8345112_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000003031 69.0
HFD2_k127_8351513_0 Tricorn protease homolog K08676 - - 0.0 1299.0
HFD2_k127_8351513_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 368.0
HFD2_k127_8351513_2 PFAM isochorismatase hydrolase K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 292.0
HFD2_k127_8351513_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 297.0
HFD2_k127_8351513_4 - - - - 0.0000000000000000000000000000000000000000001331 176.0
HFD2_k127_8351513_5 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000002717 115.0
HFD2_k127_8351513_6 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.000002408 53.0
HFD2_k127_8362555_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 420.0
HFD2_k127_8362555_1 Zn peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000001124 240.0
HFD2_k127_8362555_2 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000008637 101.0
HFD2_k127_8362555_3 Putative adhesin - - - 0.000000000001747 77.0
HFD2_k127_8403936_0 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008665 567.0
HFD2_k127_8403936_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007911 453.0
HFD2_k127_8403936_2 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 364.0
HFD2_k127_8403936_3 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 326.0
HFD2_k127_8403936_4 response to heat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 299.0
HFD2_k127_8403936_5 Fungal family of unknown function (DUF1776) - - - 0.0000000000000000000000000000000000000000000000000000000000000003289 232.0
HFD2_k127_8403936_6 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000003842 165.0
HFD2_k127_8403936_7 - - - - 0.0000000008535 70.0
HFD2_k127_8475410_0 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 420.0
HFD2_k127_8475410_1 YCII-related domain - - - 0.0000000000000000000000000000000125 130.0
HFD2_k127_8552702_0 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 346.0
HFD2_k127_8552702_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000000000004838 203.0
HFD2_k127_8552702_2 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000002594 196.0
HFD2_k127_8552702_3 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000001593 117.0
HFD2_k127_8552702_4 PFAM Uncharacterised P-loop hydrolase UPF0079 K06925 - - 0.000000000000000000005942 97.0
HFD2_k127_8552702_5 Universal bacterial protein YeaZ K14742 - - 0.00000000000002496 85.0
HFD2_k127_8552702_6 LysM domain protein - - - 0.000000001536 70.0
HFD2_k127_8552702_7 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.00001268 57.0
HFD2_k127_8553150_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005969 513.0
HFD2_k127_8553150_1 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000932 515.0
HFD2_k127_8553150_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 438.0
HFD2_k127_8553150_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 410.0
HFD2_k127_8553150_4 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 373.0
HFD2_k127_8553150_5 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 369.0
HFD2_k127_8553150_6 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006513 345.0
HFD2_k127_8553150_7 GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003979 282.0
HFD2_k127_8553150_8 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009193 277.0
HFD2_k127_8553150_9 creatininase K01470,K22232 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000001105 228.0
HFD2_k127_8565703_0 7TM receptor with intracellular HD hydrolase K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 545.0
HFD2_k127_8565703_1 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000002923 111.0
HFD2_k127_8577789_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K15408 - 1.9.3.1 3.991e-289 899.0
HFD2_k127_8577789_1 Pyrrolo-quinoline quinone K00114 - 1.1.2.8 3.021e-234 765.0
HFD2_k127_8577789_10 Amino-transferase class IV K00826 - 2.6.1.42 0.0000002402 60.0
HFD2_k127_8577789_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 344.0
HFD2_k127_8577789_3 PFAM extracellular solute-binding protein, family 3 K16254 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 293.0
HFD2_k127_8577789_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 287.0
HFD2_k127_8577789_5 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000005336 276.0
HFD2_k127_8577789_6 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K15408 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000005752 226.0
HFD2_k127_8577789_7 cytochrome c K00406 - - 0.00000000000000000000000000000002866 132.0
HFD2_k127_8577789_8 - - - - 0.00000000000000000000002128 104.0
HFD2_k127_8577789_9 inositol 2-dehydrogenase activity K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000003571 109.0
HFD2_k127_8604091_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 3.607e-229 726.0
HFD2_k127_8604091_1 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 544.0
HFD2_k127_8604091_10 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - 0.0000000000000000000000000000000000000000000000000000007159 213.0
HFD2_k127_8604091_11 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000006962 191.0
HFD2_k127_8604091_12 NDK K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000001418 185.0
HFD2_k127_8604091_13 Uncharacterised protein family (UPF0182) K09118 - - 0.000000000000000000000000000000000000007697 168.0
HFD2_k127_8604091_14 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000001531 132.0
HFD2_k127_8604091_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000005081 115.0
HFD2_k127_8604091_16 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000007211 113.0
HFD2_k127_8604091_17 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000001033 87.0
HFD2_k127_8604091_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 524.0
HFD2_k127_8604091_3 Phosphoglucomutase/phosphomannomutase, C-terminal domain K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 507.0
HFD2_k127_8604091_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 448.0
HFD2_k127_8604091_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008828 405.0
HFD2_k127_8604091_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 416.0
HFD2_k127_8604091_7 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 289.0
HFD2_k127_8604091_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000003885 282.0
HFD2_k127_8604091_9 PFAM Aspartate glutamate uridylate kinase K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000008639 246.0
HFD2_k127_864763_0 transmembrane transporter activity K18138 - - 0.0 1594.0
HFD2_k127_864763_1 Penicillin amidase K07116 - 3.5.1.97 9.021e-210 675.0
HFD2_k127_864763_10 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000971 251.0
HFD2_k127_864763_11 Pkd domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000004497 258.0
HFD2_k127_864763_12 - - - - 0.000000000000000000000000000000000000000000000000000000001674 211.0
HFD2_k127_864763_13 InterPro IPR014922 - - - 0.000000000000000000000000000000000000000000000000000000004745 205.0
HFD2_k127_864763_14 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000003123 183.0
HFD2_k127_864763_15 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000000000000000003152 170.0
HFD2_k127_864763_16 - K00003,K00058,K01754,K04517,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,1.3.1.12,4.3.1.19 0.0000000000000000000000000000000000000000000005925 176.0
HFD2_k127_864763_17 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000002532 186.0
HFD2_k127_864763_18 YCII-related domain - - - 0.0000000000000000000000000000000000000008378 151.0
HFD2_k127_864763_19 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000000001959 137.0
HFD2_k127_864763_2 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005173 608.0
HFD2_k127_864763_20 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000001101 132.0
HFD2_k127_864763_21 Domain of unknown function (DUF4260) - - - 0.000000000000000000000000000001222 131.0
HFD2_k127_864763_22 - - - - 0.0000000000000000000000008018 111.0
HFD2_k127_864763_23 PFAM YCII-related - - - 0.000000000000000000000001316 106.0
HFD2_k127_864763_24 - - - - 0.00000000000000004579 88.0
HFD2_k127_864763_25 DinB superfamily - - - 0.0000000000006346 75.0
HFD2_k127_864763_26 Subtilase family K17734 - - 0.0000000000113 78.0
HFD2_k127_864763_28 DinB superfamily - - - 0.000000002683 65.0
HFD2_k127_864763_29 Major Facilitator Superfamily - - - 0.00001877 54.0
HFD2_k127_864763_3 MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003777 584.0
HFD2_k127_864763_4 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 556.0
HFD2_k127_864763_5 efflux transmembrane transporter activity K18300,K18308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 436.0
HFD2_k127_864763_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 383.0
HFD2_k127_864763_7 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 336.0
HFD2_k127_864763_8 Releases the N-terminal proline from various substrates K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 322.0
HFD2_k127_864763_9 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001622 289.0
HFD2_k127_8654444_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005421 557.0
HFD2_k127_8654444_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 461.0
HFD2_k127_8654444_10 - - - - 0.0003961 46.0
HFD2_k127_8654444_2 mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 338.0
HFD2_k127_8654444_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 333.0
HFD2_k127_8654444_4 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000005896 229.0
HFD2_k127_8654444_5 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000001531 220.0
HFD2_k127_8654444_6 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000004495 202.0
HFD2_k127_8654444_7 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits - - - 0.0000000000000000003015 91.0
HFD2_k127_8654444_8 TonB-dependent Receptor Plug Domain - - - 0.0000000000000008381 93.0
HFD2_k127_8657717_0 Putative ATP-binding cassette K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 511.0
HFD2_k127_8657717_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 349.0
HFD2_k127_8657717_2 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000002525 177.0
HFD2_k127_8657717_3 PFAM Appr-1-p processing domain protein - - - 0.00000002241 62.0
HFD2_k127_8658501_0 Formate dehydrogenase alpha subunit K00123,K05299 - 1.17.1.10,1.17.1.9 9.148e-256 821.0
HFD2_k127_8658501_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006334 601.0
HFD2_k127_8658501_10 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000004385 147.0
HFD2_k127_8658501_11 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.000000000000000000000000003944 125.0
HFD2_k127_8658501_12 curli production assembly transport component CsgG K04087 - - 0.000000000000000000000000004257 125.0
HFD2_k127_8658501_13 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000001177 113.0
HFD2_k127_8658501_2 Beta-eliminating lyase K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 551.0
HFD2_k127_8658501_3 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 436.0
HFD2_k127_8658501_4 Zinc-binding dehydrogenase K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 423.0
HFD2_k127_8658501_5 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000002806 253.0
HFD2_k127_8658501_6 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000001803 223.0
HFD2_k127_8658501_7 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000698 218.0
HFD2_k127_8658501_8 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000003135 213.0
HFD2_k127_8658501_9 - - - - 0.00000000000000000000000000000000000000001242 168.0
HFD2_k127_8700940_0 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 302.0
HFD2_k127_8700940_1 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002261 283.0
HFD2_k127_8700940_10 DNA-templated transcription, initiation - - - 0.000000000000000000000000002213 126.0
HFD2_k127_8700940_11 PFAM transcriptional regulator domain protein - - - 0.000000000000000000000001024 121.0
HFD2_k127_8700940_12 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000008548 90.0
HFD2_k127_8700940_13 - - - - 0.000000000004093 72.0
HFD2_k127_8700940_14 phosphate-selective porin O and P K07221 - - 0.000000000008368 77.0
HFD2_k127_8700940_15 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000002044 66.0
HFD2_k127_8700940_16 Cytochrome c - - - 0.00000007795 61.0
HFD2_k127_8700940_17 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00009187 53.0
HFD2_k127_8700940_18 AP2 domain - - - 0.0002277 51.0
HFD2_k127_8700940_19 Protein of unknown function (DUF2892) - - - 0.0003476 48.0
HFD2_k127_8700940_2 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001997 270.0
HFD2_k127_8700940_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000002291 244.0
HFD2_k127_8700940_4 Histidine kinase K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000008675 227.0
HFD2_k127_8700940_5 protease with the C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000009214 220.0
HFD2_k127_8700940_6 Histidine kinase K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000006011 207.0
HFD2_k127_8700940_7 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000000000000000000000000000000001688 160.0
HFD2_k127_8700940_8 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000002446 179.0
HFD2_k127_8700940_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000004514 144.0
HFD2_k127_873280_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K00187 - 1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 644.0
HFD2_k127_873280_1 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 596.0
HFD2_k127_873280_2 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 536.0
HFD2_k127_873280_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 497.0
HFD2_k127_873280_4 negative regulation of protein lipidation K19294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 476.0
HFD2_k127_873280_5 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 437.0
HFD2_k127_873280_6 alanine dehydrogenase activity K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001424 305.0
HFD2_k127_873280_7 negative regulation of protein lipidation K19294 - - 0.0000000000000000000000000000000000000000000000000000000001013 229.0
HFD2_k127_873280_8 Bacterial Ig-like domain (group 3) K01337,K20276,K21449 - 3.4.21.50 0.00000000000000000000005618 115.0
HFD2_k127_873280_9 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.0000000000000000000001398 100.0
HFD2_k127_92215_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1192.0
HFD2_k127_92215_1 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 6.621e-239 762.0
HFD2_k127_92215_10 isoleucine patch - - - 0.00000000000000000000000000000000000000000000000000000000002296 211.0
HFD2_k127_92215_11 TrkA-C domain K03499 - - 0.0000000000000000000000000000000000000000000000000000001503 218.0
HFD2_k127_92215_12 TonB-dependent Receptor Plug - - - 0.00000000000000000000000000000000000000000000002091 196.0
HFD2_k127_92215_13 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000001662 145.0
HFD2_k127_92215_14 peptidyl-tyrosine sulfation - - - 0.0000000000000001409 95.0
HFD2_k127_92215_15 YtxH-like protein - - - 0.000000000000002624 82.0
HFD2_k127_92215_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 600.0
HFD2_k127_92215_3 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009889 474.0
HFD2_k127_92215_4 Cation transport protein K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 411.0
HFD2_k127_92215_5 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 331.0
HFD2_k127_92215_6 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 324.0
HFD2_k127_92215_7 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 317.0
HFD2_k127_92215_8 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003059 293.0
HFD2_k127_92215_9 Protein kinase domain K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000001044 254.0
HFD2_k127_947338_0 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 304.0
HFD2_k127_947338_1 Capsule assembly protein Wzi - - - 0.000000000003901 78.0
HFD2_k127_973001_0 deoxyribose-phosphate aldolase activity K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009416 471.0
HFD2_k127_973001_1 Dehydrogenase K00248,K09478 - 1.3.8.1,1.3.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005741 419.0
HFD2_k127_973001_2 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000001911 206.0
HFD2_k127_973001_3 - - - - 0.00001488 58.0
HFD2_k127_973001_4 - - - - 0.0003859 52.0
HFD2_k127_989239_0 COG1228 Imidazolonepropionase and related K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 599.0
HFD2_k127_989239_1 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 463.0
HFD2_k127_989239_2 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 445.0
HFD2_k127_989239_3 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 431.0
HFD2_k127_989239_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002383 293.0
HFD2_k127_989239_5 carboxylic acid catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000007851 213.0
HFD2_k127_989239_6 PFAM peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.000000000005533 79.0