logo

Overview

ID MAG01640
Name HFD2_bin.29
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Gemmatimonadota
Class Gemmatimonadetes
Order Longimicrobiales
Family RSA9
Genus JADGQX01
Species
Assembly information
Completeness (%) 85.91
Contamination (%) 3.62
GC content (%) 71.0
N50 (bp) 15,573
Genome size (bp) 5,157,169

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3865

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_1061481_0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 2.097e-251 798.0
HFD2_k127_1061481_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 4.419e-203 649.0
HFD2_k127_1061481_10 permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 298.0
HFD2_k127_1061481_11 Pfam:SusD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005403 279.0
HFD2_k127_1061481_12 PspA/IM30 family K03969 - - 0.000000000000000000000000000000000000000000000000000000000000000000001232 248.0
HFD2_k127_1061481_13 - - - - 0.00000000000000000000000000000000000000000000000000000001794 211.0
HFD2_k127_1061481_14 6-phosphogluconolactonase activity - - - 0.00000000000000000000000000000000000000000000988 171.0
HFD2_k127_1061481_15 BadF/BadG/BcrA/BcrD ATPase family K18676 - 2.7.1.8 0.0000000000000000000000000000000000015 150.0
HFD2_k127_1061481_16 - - - - 0.0000000000000000000000008489 109.0
HFD2_k127_1061481_17 Gram-negative bacterial TonB protein C-terminal - - - 0.00000000000000007083 90.0
HFD2_k127_1061481_18 TonB-linked outer membrane protein, SusC RagA family - - - 0.0000001912 61.0
HFD2_k127_1061481_2 TonB-dependent receptor - - - 1.175e-201 665.0
HFD2_k127_1061481_3 CarboxypepD_reg-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 604.0
HFD2_k127_1061481_4 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 505.0
HFD2_k127_1061481_5 Glycosyl hydrolase family 3 C-terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 472.0
HFD2_k127_1061481_6 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 451.0
HFD2_k127_1061481_7 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 435.0
HFD2_k127_1061481_8 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 378.0
HFD2_k127_1061481_9 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 365.0
HFD2_k127_1067195_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 9.16e-314 977.0
HFD2_k127_1067195_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.431e-218 687.0
HFD2_k127_1067195_2 O-acyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 302.0
HFD2_k127_1067195_3 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000732 256.0
HFD2_k127_1067195_4 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000001234 246.0
HFD2_k127_1067195_5 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.00000000000000000000000000000000000000000000000000000000002482 222.0
HFD2_k127_1067195_6 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000000000000000000000000000004869 160.0
HFD2_k127_1067195_7 - - - - 0.00000000000005138 84.0
HFD2_k127_1067195_8 translation release factor activity - - - 0.000000000001062 79.0
HFD2_k127_1067195_9 - - - - 0.00000000001257 74.0
HFD2_k127_1106470_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 3.468e-260 828.0
HFD2_k127_1106470_1 Peptidase, S9A B C family, catalytic domain protein K01322 - 3.4.21.26 4.089e-197 639.0
HFD2_k127_1106470_10 Nitrogen regulatory protein P-II K04751 - - 0.000000000000000000000000000000000000000000000000003833 185.0
HFD2_k127_1106470_11 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000025 149.0
HFD2_k127_1106470_2 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 559.0
HFD2_k127_1106470_3 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009599 554.0
HFD2_k127_1106470_4 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005779 332.0
HFD2_k127_1106470_5 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006274 280.0
HFD2_k127_1106470_6 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001454 261.0
HFD2_k127_1106470_7 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000004982 223.0
HFD2_k127_1106470_8 SIS domain K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000001576 213.0
HFD2_k127_1106470_9 ZIP Zinc transporter K07238,K16267 - - 0.000000000000000000000000000000000000000000000000000003602 199.0
HFD2_k127_1133182_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000001672 119.0
HFD2_k127_1133182_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000764 66.0
HFD2_k127_117550_0 Alpha-glucan phosphorylase K00688 - 2.4.1.1 0.0 1071.0
HFD2_k127_117550_1 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008781 572.0
HFD2_k127_117550_2 7TM receptor with intracellular HD hydrolase K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 466.0
HFD2_k127_117550_3 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 393.0
HFD2_k127_117550_4 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 352.0
HFD2_k127_117550_5 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 301.0
HFD2_k127_117550_6 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000387 287.0
HFD2_k127_117550_7 B12 binding domain - - - 0.000000000000000000000000000000000000000007535 164.0
HFD2_k127_117550_8 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000003358 130.0
HFD2_k127_117550_9 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000004553 114.0
HFD2_k127_1181205_0 Helix-hairpin-helix motif K14162 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 588.0
HFD2_k127_1181205_1 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 564.0
HFD2_k127_1181205_2 membrane - - - 0.00000000000000000009281 95.0
HFD2_k127_1181205_3 - - - - 0.000000000000001222 90.0
HFD2_k127_1181205_4 Belongs to the ClpA ClpB family K03695,K03696 - - 0.00000000000003967 83.0
HFD2_k127_1181205_5 Transcriptional regulator K07979 - - 0.0000000000007345 79.0
HFD2_k127_1181205_6 Rad51 - - - 0.0000000002906 70.0
HFD2_k127_1181205_7 ATPase AAA-2 domain protein K03696 - - 0.00000001214 63.0
HFD2_k127_1181205_8 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.0000004521 63.0
HFD2_k127_1181730_0 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 513.0
HFD2_k127_1181730_1 domain, Protein K01179,K07260,K13735 - 3.2.1.4,3.4.17.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 355.0
HFD2_k127_1181730_2 MgtE intracellular - - - 0.00000000000000000000000000000000000000000000000000000000006002 222.0
HFD2_k127_1181730_3 glyoxalase bleomycin resistance protein dioxygenase K07104 - 1.13.11.2 0.00000000000000000000000000000000000000001195 158.0
HFD2_k127_1181730_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.000000000000000000000000000000000000001565 154.0
HFD2_k127_1181730_5 DoxX K15977 - - 0.000000000000000000000000000000008756 134.0
HFD2_k127_1181730_6 CarboxypepD_reg-like domain - - - 0.0000000000000000000000000000001748 129.0
HFD2_k127_1240146_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 7.265e-242 765.0
HFD2_k127_1240146_1 B12 binding domain K00197,K00548,K15023 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0030312,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13,2.1.1.245,2.1.1.258 2.81e-199 640.0
HFD2_k127_1240146_2 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003147 249.0
HFD2_k127_1240146_3 23S rRNA-intervening sequence protein - - - 0.000000000001737 74.0
HFD2_k127_1257451_0 Carboxypeptidase regulatory-like domain K02014 - - 0.00000000000001085 81.0
HFD2_k127_1257451_1 SatD family (SatD) - - - 0.0000003431 59.0
HFD2_k127_1261190_0 Male sterility protein K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 482.0
HFD2_k127_1261190_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 412.0
HFD2_k127_1261190_2 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 306.0
HFD2_k127_1261190_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003861 254.0
HFD2_k127_1261190_4 Competence-damaged protein K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000001944 235.0
HFD2_k127_1261190_5 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000006811 156.0
HFD2_k127_1261190_6 Roadblock/LC7 domain - - - 0.0000000000000000000000000000001265 134.0
HFD2_k127_1261190_7 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000004167 108.0
HFD2_k127_1261190_8 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000009584 113.0
HFD2_k127_1261190_9 - - - - 0.0000000000002006 79.0
HFD2_k127_1279606_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 1.734e-214 715.0
HFD2_k127_1279606_1 Glycosyl hydrolase family 53 K01224 - 3.2.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 477.0
HFD2_k127_1279606_2 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000004036 165.0
HFD2_k127_1279606_3 Heparinase II/III-like protein - - - 0.00000000000000000000000000006093 133.0
HFD2_k127_1279606_4 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000944 111.0
HFD2_k127_1325184_0 Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000000002541 223.0
HFD2_k127_1325184_1 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000001476 178.0
HFD2_k127_1325184_2 CcmB protein K02194 - - 0.0000000000000000000000000000000000000000000002235 179.0
HFD2_k127_1325184_3 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000001488 139.0
HFD2_k127_1325184_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000001002 90.0
HFD2_k127_1343195_0 YidE YbjL duplication domain protein K07085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 479.0
HFD2_k127_1343195_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 432.0
HFD2_k127_1343195_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000008694 59.0
HFD2_k127_1343195_3 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000009586 58.0
HFD2_k127_1348141_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 1.251e-236 741.0
HFD2_k127_1348141_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.095e-229 742.0
HFD2_k127_1348141_10 PFAM Clp - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000003833 55.0
HFD2_k127_1348141_2 MFS/sugar transport protein K16211 - - 5.601e-212 666.0
HFD2_k127_1348141_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 541.0
HFD2_k127_1348141_4 hydrolase activity, hydrolyzing O-glycosyl compounds K01176 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008518 523.0
HFD2_k127_1348141_5 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 326.0
HFD2_k127_1348141_6 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001323 273.0
HFD2_k127_1348141_7 PFAM amino acid-binding ACT domain protein K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000343 197.0
HFD2_k127_1348141_8 Transcriptional regulator K07979 - - 0.0000000000000000000000000000000000000002263 157.0
HFD2_k127_1349476_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 449.0
HFD2_k127_1349476_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000007032 276.0
HFD2_k127_1349476_2 translation initiation factor activity K06996 - - 0.00000000000000000000000000000000000000000000000000000000000000000002993 240.0
HFD2_k127_1349476_3 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000000000000000309 218.0
HFD2_k127_1349476_4 NADP oxidoreductase coenzyme F420-dependent - - - 0.0000000000000000000000000000000000000009895 166.0
HFD2_k127_1349476_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000001075 123.0
HFD2_k127_1349476_6 Protein of unknown function (DUF3788) - - - 0.000000000000001557 85.0
HFD2_k127_1349476_7 Late embryogenesis abundant protein - - - 0.000000000002004 78.0
HFD2_k127_1349476_8 - - - - 0.0000000007928 71.0
HFD2_k127_1350038_0 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 613.0
HFD2_k127_1350038_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 409.0
HFD2_k127_1350038_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000001553 221.0
HFD2_k127_135167_0 Pfam:KaiC K08482 - - 1.789e-207 664.0
HFD2_k127_135167_1 KaiB K08481 - - 0.0000000000000000000000000000000000006795 147.0
HFD2_k127_135167_2 - - - - 0.00000000000000000000000000000233 124.0
HFD2_k127_135167_3 Domain of unknown function (DUF309) K09763 - - 0.000000002789 64.0
HFD2_k127_1359662_0 Berberine and berberine like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000636 594.0
HFD2_k127_1359662_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007318 577.0
HFD2_k127_1359662_2 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000000000003692 162.0
HFD2_k127_1359662_3 Peptidase family M1 domain - - - 0.000000000000000000000000000003034 139.0
HFD2_k127_1359662_4 Protein of unknown function (DUF3311) - - - 0.0000000000000002727 82.0
HFD2_k127_1359662_5 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.000000000000003778 86.0
HFD2_k127_1364996_0 Bacterial membrane protein, YfhO - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002028 268.0
HFD2_k127_1364996_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000004705 92.0
HFD2_k127_1408433_0 AcrB/AcrD/AcrF family K07787,K15726 - - 0.0 1197.0
HFD2_k127_1438921_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 1.382e-287 900.0
HFD2_k127_1438921_1 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 599.0
HFD2_k127_1438921_10 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000001318 160.0
HFD2_k127_1438921_11 Domain of unknown function (DUF1906) - - - 0.00000000002079 68.0
HFD2_k127_1438921_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 504.0
HFD2_k127_1438921_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 434.0
HFD2_k127_1438921_4 Glucose Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 417.0
HFD2_k127_1438921_5 glycosyl transferase group 1 K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009756 410.0
HFD2_k127_1438921_6 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 347.0
HFD2_k127_1438921_7 TatD related DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001547 259.0
HFD2_k127_1438921_8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005043 254.0
HFD2_k127_1438921_9 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000004393 228.0
HFD2_k127_1457045_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 430.0
HFD2_k127_1457045_1 glycoside hydrolase family 38 K01191 - 3.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 332.0
HFD2_k127_1457045_2 FR47-like protein K06976 - - 0.000000000003659 72.0
HFD2_k127_1457045_3 FR47-like protein K06976 - - 0.00000000004492 69.0
HFD2_k127_1467630_0 COG NOG06097 non supervised orthologous group - - - 0.0 1340.0
HFD2_k127_1467630_1 metallopeptidase activity K01183 - 3.2.1.14 0.0 1123.0
HFD2_k127_1467630_2 Belongs to the glycosyl hydrolase 43 family K01198,K01209 - 3.2.1.37,3.2.1.55 7.579e-240 757.0
HFD2_k127_1467630_3 alpha-L-arabinofuranosidase K01209 - 3.2.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 573.0
HFD2_k127_1467630_4 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 465.0
HFD2_k127_1467630_5 converts alpha-aldose to the beta-anomer K00849,K01785 GO:0003674,GO:0003824,GO:0004034,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006012,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 2.7.1.6,5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 435.0
HFD2_k127_1467630_6 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 404.0
HFD2_k127_1467630_7 FCD - - - 0.000000000000000000000000000000000000000000001611 175.0
HFD2_k127_1496224_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.0 1235.0
HFD2_k127_1496224_1 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - - 9.728e-258 824.0
HFD2_k127_1496224_10 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 317.0
HFD2_k127_1496224_11 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000589 303.0
HFD2_k127_1496224_12 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009965 288.0
HFD2_k127_1496224_13 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000008477 254.0
HFD2_k127_1496224_14 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000264 253.0
HFD2_k127_1496224_15 PFAM Asparaginase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000007703 244.0
HFD2_k127_1496224_16 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000002018 225.0
HFD2_k127_1496224_17 PFAM CoA-binding domain protein K06929 - - 0.0000000000000000000000000000000000000000002909 169.0
HFD2_k127_1496224_18 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000001309 168.0
HFD2_k127_1496224_19 protein conserved in bacteria - - - 0.000000000000000000000000000000000001724 153.0
HFD2_k127_1496224_2 phosphorelay signal transduction system K12132 - 2.7.11.1 5.946e-218 713.0
HFD2_k127_1496224_20 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000002423 124.0
HFD2_k127_1496224_21 efflux transmembrane transporter activity - - - 0.00000000000000000000000001955 128.0
HFD2_k127_1496224_22 - - - - 0.000000000000000000000001645 119.0
HFD2_k127_1496224_24 PFAM GCN5-related N-acetyltransferase K00619 - 2.3.1.1 0.00000000000000008134 95.0
HFD2_k127_1496224_27 - - - - 0.0002577 53.0
HFD2_k127_1496224_3 Periplasmic component of the Tol biopolymer transport system - - - 5.284e-207 654.0
HFD2_k127_1496224_4 Permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006375 556.0
HFD2_k127_1496224_5 Involved in arsenical resistance. Thought to form the channel of an arsenite pump - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 526.0
HFD2_k127_1496224_6 alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity K16055 - 2.4.1.15,3.1.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 435.0
HFD2_k127_1496224_7 Class II aldolase adducin family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 418.0
HFD2_k127_1496224_8 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 355.0
HFD2_k127_1496224_9 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 301.0
HFD2_k127_1521770_0 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 501.0
HFD2_k127_1521770_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 414.0
HFD2_k127_1521770_2 Regulator of chromosome condensation (RCC1) repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006992 291.0
HFD2_k127_1521770_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000442 112.0
HFD2_k127_1521770_4 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000008728 84.0
HFD2_k127_1521770_5 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000004451 64.0
HFD2_k127_1570935_0 ligase activity, forming nitrogen-metal bonds K02230 - 6.6.1.2 0.0 1287.0
HFD2_k127_1570935_1 Glycogen debranching enzyme - - - 1.631e-255 808.0
HFD2_k127_1570935_2 Two component regulator three Y domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 647.0
HFD2_k127_1570935_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00520 - 1.16.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 571.0
HFD2_k127_1570935_4 water channel activity K02440,K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000143 265.0
HFD2_k127_1570935_5 Sigma-70, region 4 K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000005896 207.0
HFD2_k127_1570935_6 Pentapeptide repeats (9 copies) - - - 0.0000000000000000003403 100.0
HFD2_k127_1586152_0 Belongs to the glycosyl hydrolase 57 family - - - 2.075e-315 991.0
HFD2_k127_1586152_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 3.47e-284 886.0
HFD2_k127_1586152_10 - - - - 0.000001471 58.0
HFD2_k127_1586152_11 Polymer-forming cytoskeletal - - - 0.000002396 60.0
HFD2_k127_1586152_2 Alpha amylase, catalytic domain K06044 - 5.4.99.15 1.615e-226 734.0
HFD2_k127_1586152_3 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700,K01236 - 2.4.1.18,3.2.1.141 6.03e-220 706.0
HFD2_k127_1586152_4 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 559.0
HFD2_k127_1586152_5 SMART alpha amylase, catalytic sub domain K05343 - 3.2.1.1,5.4.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 335.0
HFD2_k127_1586152_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000002627 258.0
HFD2_k127_1586152_7 ECF sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000002154 231.0
HFD2_k127_1586152_8 membrane K11622 - - 0.00000000000000000000000000000000001984 147.0
HFD2_k127_1586152_9 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000004614 101.0
HFD2_k127_1604049_0 Tricorn protease homolog K08676 - - 0.0 1329.0
HFD2_k127_1604049_1 Thioesterase-like superfamily K10805 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 365.0
HFD2_k127_1604049_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 341.0
HFD2_k127_1604049_3 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 316.0
HFD2_k127_1604049_4 protein kinase activity - - - 0.0000000000000000375 90.0
HFD2_k127_1604049_5 Penicillin amidase K01434 - 3.5.1.11 0.00000000000001108 82.0
HFD2_k127_160487_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1276.0
HFD2_k127_160487_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001085 287.0
HFD2_k127_160487_2 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001032 258.0
HFD2_k127_160487_3 transcriptional regulators - - - 0.0000000000006201 78.0
HFD2_k127_160487_4 23S rRNA-intervening sequence protein - - - 0.00003421 49.0
HFD2_k127_1643694_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 566.0
HFD2_k127_1643694_1 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001528 297.0
HFD2_k127_1643694_2 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001903 276.0
HFD2_k127_1643694_3 GGDEF domain K11527 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000007576 222.0
HFD2_k127_1643694_4 Conserved TM helix - - - 0.00000000000000000000000000000000000000000000000000000008118 204.0
HFD2_k127_1643694_5 response regulator K22010 - - 0.00000000000000000000000000000000000000001584 164.0
HFD2_k127_1643694_6 Cell wall-associated hydrolase (invasion-associated protein) - - - 0.00000000000000000000000000000000003518 149.0
HFD2_k127_1643694_7 Ferric uptake regulator family K09825 - - 0.000000000000000000000002146 109.0
HFD2_k127_1643694_8 response regulator, receiver K09763 - - 0.0000009923 55.0
HFD2_k127_1643694_9 Lysin motif - - - 0.000007879 59.0
HFD2_k127_1652099_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 607.0
HFD2_k127_1652099_1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281,K12132 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0030145,GO:0034641,GO:0034654,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.11.1,3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000007872 250.0
HFD2_k127_1652099_2 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000001335 207.0
HFD2_k127_1652099_3 Protein of unknown function (DUF3592) - - - 0.000000004543 65.0
HFD2_k127_1683826_0 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 465.0
HFD2_k127_1683826_1 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 310.0
HFD2_k127_1683826_2 PFAM beta-lactamase domain protein - - - 0.00000000194 61.0
HFD2_k127_1693655_0 PglZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 553.0
HFD2_k127_1693655_1 ABC transporter transmembrane region K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000899 503.0
HFD2_k127_1693655_2 Glycosyltransferase family 9 (heptosyltransferase) K02841,K02843,K02849,K12982 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 368.0
HFD2_k127_1693655_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002919 280.0
HFD2_k127_1693655_4 Glycosyl transferase family 2 K08301 - - 0.000000000000000000000000000000000000000000000003071 196.0
HFD2_k127_1693655_5 sequence-specific DNA binding K03719 - - 0.00000000000000000000000000000000000000000000004643 174.0
HFD2_k127_1693655_6 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000002721 181.0
HFD2_k127_1693655_7 Glycosyl transferase 4-like - - - 0.0000000000000000000000000000000001837 147.0
HFD2_k127_1693655_8 ADP-heptose LPS heptosyltransferase - GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000007692 145.0
HFD2_k127_1731208_0 Nucleoside H+ symporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 585.0
HFD2_k127_1731208_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001122 267.0
HFD2_k127_1731208_2 Belongs to the peptidase S33 family - - - 0.00000000000000000000000000000000000000000000000000009553 211.0
HFD2_k127_1731208_3 - - - - 0.000000000000000000000000000000004348 145.0
HFD2_k127_1731208_4 phage shock operon rhodanese PspE K03972 - - 0.0000000000000000001877 95.0
HFD2_k127_1773009_0 glucuronate isomerase activity K01812 - 5.3.1.12 1.216e-225 712.0
HFD2_k127_1773009_1 glycolate transport K14393 - - 7.908e-200 630.0
HFD2_k127_1773009_10 Protein of unknown function, DUF485 - - - 0.0000000000000000000000003986 122.0
HFD2_k127_1773009_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 596.0
HFD2_k127_1773009_3 tagaturonate epimerase K21619 - 5.1.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 572.0
HFD2_k127_1773009_4 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 517.0
HFD2_k127_1773009_5 mannitol metabolic process K00009,K00041 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0009026,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.1.1.17,1.1.1.58 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 462.0
HFD2_k127_1773009_6 PFAM Prenyltransferase squalene oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 430.0
HFD2_k127_1773009_7 2-dehydro-3-deoxy-phosphogluconate aldolase activity K00874,K01625 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.1.45,4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 307.0
HFD2_k127_1773009_8 glycolate transport K14393 - - 0.0000000000000000000000000000000001803 132.0
HFD2_k127_1773009_9 TonB-dependent Receptor Plug Domain - - - 0.000000000000000000000000000001499 128.0
HFD2_k127_1782559_0 Belongs to the peptidase S16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 595.0
HFD2_k127_1782559_1 epoxide hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 571.0
HFD2_k127_1782559_2 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000008541 179.0
HFD2_k127_1782559_3 - - - - 0.000000000000000000000000002442 119.0
HFD2_k127_1782559_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000002481 95.0
HFD2_k127_1790446_0 - - - - 0.0 1023.0
HFD2_k127_1790446_1 Beta-L-arabinofuranosidase, GH127 K09955 - - 3.333e-252 803.0
HFD2_k127_1790446_2 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 536.0
HFD2_k127_1790446_3 Dihydrodipicolinate synthetase family K21062 - 3.5.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 333.0
HFD2_k127_1792255_0 radical SAM domain protein - - - 4.169e-207 664.0
HFD2_k127_1792255_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 458.0
HFD2_k127_1792255_2 Band 7 protein K07192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008239 426.0
HFD2_k127_1792255_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001903 243.0
HFD2_k127_1792255_4 - - - - 0.00000000000000000000000000000000000000000000661 174.0
HFD2_k127_1803104_0 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 338.0
HFD2_k127_1803104_1 BlaR1 peptidase M56 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007237 304.0
HFD2_k127_1803104_10 - - - - 0.000000000000000001979 94.0
HFD2_k127_1803104_11 VIT family - - - 0.00004403 55.0
HFD2_k127_1803104_2 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000000000006375 187.0
HFD2_k127_1803104_3 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000000359 167.0
HFD2_k127_1803104_4 L,D-transpeptidase catalytic domain K21470 - - 0.0000000000000000000000000000000000000000001004 175.0
HFD2_k127_1803104_5 HEAT repeat - - - 0.0000000000000000000000000000000000000000003566 177.0
HFD2_k127_1803104_6 SnoaL-like domain - - - 0.00000000000000000000000000000000001319 147.0
HFD2_k127_1803104_7 Penicillinase repressor - - - 0.0000000000000000000000000000000002152 147.0
HFD2_k127_1803104_8 Sigma-70 region 2 K03088 - - 0.00000000000000000000000002564 115.0
HFD2_k127_1803104_9 gag-polyprotein putative aspartyl protease - - - 0.0000000000000000005508 89.0
HFD2_k127_1852150_0 FAD linked oxidases, C-terminal domain - - - 0.0 1208.0
HFD2_k127_1852150_1 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1060.0
HFD2_k127_1852150_10 Anabaena sensory rhodopsin transducer - - - 0.00000000000000000000000000000000000000000000000000007639 192.0
HFD2_k127_1852150_12 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000009436 178.0
HFD2_k127_1852150_13 Squalene--hopene cyclase - - - 0.0000000000000000000000000000000000000000000008991 176.0
HFD2_k127_1852150_14 TIGRFAM cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000002776 159.0
HFD2_k127_1852150_15 dTDP-4-dehydrorhamnose 3,5-epimerase activity K19068 - 1.1.1.367 0.000000000000000000000007892 108.0
HFD2_k127_1852150_16 Gram-negative-bacterium-type cell wall biogenesis - - - 0.000000000000000000004356 104.0
HFD2_k127_1852150_17 PFAM iron dependent repressor K03709 - - 0.00000000001195 70.0
HFD2_k127_1852150_18 alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000122 66.0
HFD2_k127_1852150_19 transcriptional regulator - - - 0.0000002855 60.0
HFD2_k127_1852150_2 Tex-like protein N-terminal domain K06959 - - 3.532e-311 969.0
HFD2_k127_1852150_20 - - - - 0.000002727 60.0
HFD2_k127_1852150_21 Alcohol dehydrogenase GroES-like domain K00121 - 1.1.1.1,1.1.1.284 0.0009972 48.0
HFD2_k127_1852150_3 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 1.12e-213 686.0
HFD2_k127_1852150_4 TamB, inner membrane protein subunit of TAM complex K09800 - - 8.083e-211 696.0
HFD2_k127_1852150_5 Sugar (and other) transporter K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 567.0
HFD2_k127_1852150_6 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 523.0
HFD2_k127_1852150_7 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 342.0
HFD2_k127_1852150_8 SelR domain K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000101 231.0
HFD2_k127_1852150_9 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000001182 233.0
HFD2_k127_1873367_0 Peptidase family M49 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 446.0
HFD2_k127_1873367_1 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005484 420.0
HFD2_k127_1873367_2 SPFH Band 7 PHB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000013 287.0
HFD2_k127_1873367_3 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000001561 203.0
HFD2_k127_1873367_4 PFAM deoxynucleoside kinase - - - 0.0000000000000000000000000000005449 132.0
HFD2_k127_1873367_5 Peptidase family M28 - - - 0.000000000000000000000000009206 126.0
HFD2_k127_1873367_6 transcriptional activator domain - - - 0.00000000000000000000007159 116.0
HFD2_k127_1873367_7 - - - - 0.0000000000000000001997 94.0
HFD2_k127_1873367_8 Transcriptional regulator, GntR family - - - 0.00000007454 61.0
HFD2_k127_1873367_9 Bacterial Ig-like domain (group 3) - - - 0.0000002647 61.0
HFD2_k127_1879716_0 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005032 417.0
HFD2_k127_1879716_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006851 359.0
HFD2_k127_1879716_10 EthD domain - - - 0.0000000000000000001787 92.0
HFD2_k127_1879716_11 Part of the ABC transporter complex PstSACB involved in phosphate import - - - 0.000000000000000003182 101.0
HFD2_k127_1879716_2 DNA mismatch repair protein MutS - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003939 259.0
HFD2_k127_1879716_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000004051 213.0
HFD2_k127_1879716_4 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000003229 178.0
HFD2_k127_1879716_5 - - - - 0.000000000000000000000000000000000005473 145.0
HFD2_k127_1879716_6 unfolded protein binding - - - 0.00000000000000000000000000000002754 145.0
HFD2_k127_1879716_7 methyltransferase activity - - - 0.00000000000000000000000000001106 135.0
HFD2_k127_1879716_8 Transglycosylase associated protein - - - 0.0000000000000000000000001682 114.0
HFD2_k127_1880089_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 451.0
HFD2_k127_1880089_1 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000001194 279.0
HFD2_k127_1880089_10 ATP hydrolysis coupled proton transport K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000375 74.0
HFD2_k127_1880089_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000001193 252.0
HFD2_k127_1880089_3 Catalyzes the formation of 2-oxobutanoate from L-threonine K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000001068 229.0
HFD2_k127_1880089_4 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000001306 236.0
HFD2_k127_1880089_5 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000012 222.0
HFD2_k127_1880089_6 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000002464 210.0
HFD2_k127_1880089_7 RNA 2'-O ribose methyltransferase substrate binding K03437 - - 0.00000000000000000000000000000000000000001802 175.0
HFD2_k127_1880089_8 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000002125 166.0
HFD2_k127_1880089_9 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000002365 156.0
HFD2_k127_1890098_0 Ftsk_gamma K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 627.0
HFD2_k127_1890098_1 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 604.0
HFD2_k127_1890098_2 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 519.0
HFD2_k127_1890098_3 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 417.0
HFD2_k127_1890098_4 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.0000000000000000000000000000000000000000001946 168.0
HFD2_k127_1890098_5 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000009693 115.0
HFD2_k127_1896257_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 552.0
HFD2_k127_1896257_1 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 476.0
HFD2_k127_1896257_2 Pterin binding enzyme K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 443.0
HFD2_k127_1896257_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 414.0
HFD2_k127_1896257_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009689 415.0
HFD2_k127_1896257_5 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 406.0
HFD2_k127_1896257_6 PFAM Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 362.0
HFD2_k127_1896257_7 Probable molybdopterin binding domain K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000006793 178.0
HFD2_k127_1896257_8 Bacterial Ig-like domain 2 - - - 0.0000002564 63.0
HFD2_k127_1896257_9 PFAM Bacterial Ig-like domain (group 2) - - - 0.000023 57.0
HFD2_k127_1908132_0 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 447.0
HFD2_k127_1908132_1 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 404.0
HFD2_k127_1908132_2 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000904 243.0
HFD2_k127_1908132_3 YCII-related domain - - - 0.00000000000000000000000000000000000151 146.0
HFD2_k127_1916740_0 PFAM Alcohol dehydrogenase, zinc-binding K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 369.0
HFD2_k127_1916740_1 Glycosyl transferase family 21 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000002564 273.0
HFD2_k127_1916740_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005556 255.0
HFD2_k127_1916740_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002627 254.0
HFD2_k127_1916740_4 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000003489 153.0
HFD2_k127_1916740_5 PFAM MazG nucleotide pyrophosphohydrolase - - - 0.00000000000000000000000000000000005485 142.0
HFD2_k127_1916740_6 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000002707 150.0
HFD2_k127_1916740_7 Transglutaminase-like superfamily - - - 0.00000008603 61.0
HFD2_k127_1916740_8 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00002767 51.0
HFD2_k127_1941374_0 Prolyl oligopeptidase family K01303 - 3.4.19.1 2.114e-265 838.0
HFD2_k127_1941374_1 cytochrome c peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 431.0
HFD2_k127_1941374_2 - - - - 0.0000000000000000000000000000000000000004405 164.0
HFD2_k127_1941374_3 Cold shock protein domain K03704 - - 0.000000000000000000000000000000001206 130.0
HFD2_k127_1941374_4 Helix-turn-helix XRE-family like proteins K21498 - - 0.00000000000000000000000000000004973 126.0
HFD2_k127_1941374_5 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000001966 118.0
HFD2_k127_1941374_6 Leucine-rich repeat (LRR) protein - - - 0.0000000000000003751 91.0
HFD2_k127_1941374_7 PFAM ribonuclease II K01147 - 3.1.13.1 0.00000000002352 66.0
HFD2_k127_1941374_8 positive regulation of growth - - - 0.000000001432 63.0
HFD2_k127_1965136_0 Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 325.0
HFD2_k127_1965136_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000002058 191.0
HFD2_k127_1965136_2 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000299 155.0
HFD2_k127_1965136_3 Forkhead associated domain - - - 0.00000000000000000001604 102.0
HFD2_k127_1965136_4 PFAM Flavin reductase like domain - - - 0.0000000000000001244 93.0
HFD2_k127_1970831_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006334 601.0
HFD2_k127_1970831_1 alcohol dehydrogenase K00008,K00060 - 1.1.1.103,1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 300.0
HFD2_k127_1981520_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1142.0
HFD2_k127_1981520_1 FtsX-like permease family K02004 - - 1.756e-238 760.0
HFD2_k127_1981520_10 hydrolase of the alpha beta-hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003131 287.0
HFD2_k127_1981520_11 - - - - 0.00000000000000000000000000000000000000000000000000000000002435 217.0
HFD2_k127_1981520_12 Histidine biosynthesis protein K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000023 211.0
HFD2_k127_1981520_13 NADPH-dependent FMN reductase K19784 - - 0.00000000000000000000000000000000000000000000000000000003701 203.0
HFD2_k127_1981520_14 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000008792 209.0
HFD2_k127_1981520_15 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000000000000000000000000015 200.0
HFD2_k127_1981520_16 MotA/TolQ/ExbB proton channel family K03562 - - 0.0000000000000000000000000000000000000000000000000003232 195.0
HFD2_k127_1981520_17 Regulator of chromosome condensation (RCC1) repeat - - - 0.000000000000000000000000000000000000000000000000000397 209.0
HFD2_k127_1981520_18 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000975 193.0
HFD2_k127_1981520_19 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000009301 167.0
HFD2_k127_1981520_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 2.572e-218 722.0
HFD2_k127_1981520_20 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000001057 169.0
HFD2_k127_1981520_21 Transcriptional regulator PadR-like family - - - 0.000000000000000000000003211 106.0
HFD2_k127_1981520_22 - - - - 0.000000000000000000000006332 111.0
HFD2_k127_1981520_23 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000006868 107.0
HFD2_k127_1981520_24 RHS Repeat - GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0004549,GO:0006139,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016078,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575 - 0.000000001305 66.0
HFD2_k127_1981520_25 TIGRFAM RHS repeat-associated core domain - - - 0.000000004514 64.0
HFD2_k127_1981520_26 efflux transmembrane transporter activity - - - 0.00000002701 64.0
HFD2_k127_1981520_27 Bacterial Ig-like domain 2 - - - 0.00004755 54.0
HFD2_k127_1981520_28 hydrolase, family 3 - - - 0.00009911 53.0
HFD2_k127_1981520_3 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 557.0
HFD2_k127_1981520_4 Peptidase family S41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 375.0
HFD2_k127_1981520_5 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 362.0
HFD2_k127_1981520_6 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 347.0
HFD2_k127_1981520_7 response regulator K10943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 343.0
HFD2_k127_1981520_8 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 344.0
HFD2_k127_1981520_9 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 317.0
HFD2_k127_199090_0 Serine hydroxymethyltransferase K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 554.0
HFD2_k127_199090_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000001668 268.0
HFD2_k127_199090_2 - - - - 0.000000000000000000000000000000000002812 142.0
HFD2_k127_199090_3 - - - - 0.0000000000000000000000000000002089 123.0
HFD2_k127_199090_4 Two component regulator propeller - - - 0.0000000002748 70.0
HFD2_k127_2002463_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 345.0
HFD2_k127_2002463_1 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 361.0
HFD2_k127_2002463_2 VanZ like family - - - 0.00000000000000000000005585 113.0
HFD2_k127_2002463_3 Low molecular weight phosphotyrosine protein phosphatase K01104,K20201 - 3.1.3.48,3.9.1.2 0.00000000000001045 85.0
HFD2_k127_2002463_4 CarboxypepD_reg-like domain - - - 0.00000000000003083 87.0
HFD2_k127_2030170_0 UDP binding domain K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 577.0
HFD2_k127_2030170_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 537.0
HFD2_k127_2030170_10 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000007553 247.0
HFD2_k127_2030170_11 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000001124 240.0
HFD2_k127_2030170_12 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000001577 238.0
HFD2_k127_2030170_13 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000004244 235.0
HFD2_k127_2030170_14 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000003019 216.0
HFD2_k127_2030170_15 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000002237 216.0
HFD2_k127_2030170_16 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000001195 205.0
HFD2_k127_2030170_17 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000937 220.0
HFD2_k127_2030170_18 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000007249 200.0
HFD2_k127_2030170_19 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000003372 190.0
HFD2_k127_2030170_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009994 466.0
HFD2_k127_2030170_20 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000108 187.0
HFD2_k127_2030170_21 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000002118 189.0
HFD2_k127_2030170_22 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000002057 160.0
HFD2_k127_2030170_23 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000004066 154.0
HFD2_k127_2030170_24 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000004066 150.0
HFD2_k127_2030170_25 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000003617 145.0
HFD2_k127_2030170_26 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000007367 130.0
HFD2_k127_2030170_27 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000001661 130.0
HFD2_k127_2030170_28 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000001024 117.0
HFD2_k127_2030170_29 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000003249 116.0
HFD2_k127_2030170_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 391.0
HFD2_k127_2030170_30 Transcription termination factor nusG - - - 0.000000000000000000000000001026 120.0
HFD2_k127_2030170_31 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000002959 115.0
HFD2_k127_2030170_32 Glycosyl transferases group 1 - - - 0.00000000000000000000000007444 121.0
HFD2_k127_2030170_33 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000003126 108.0
HFD2_k127_2030170_34 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000003418 83.0
HFD2_k127_2030170_35 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000003926 77.0
HFD2_k127_2030170_36 Ribosomal protein L36 K02919 - - 0.00000000000001497 73.0
HFD2_k127_2030170_37 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000007347 71.0
HFD2_k127_2030170_38 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000007061 72.0
HFD2_k127_2030170_4 rRNA binding K02886 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 385.0
HFD2_k127_2030170_5 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009222 342.0
HFD2_k127_2030170_6 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 316.0
HFD2_k127_2030170_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 292.0
HFD2_k127_2030170_8 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 300.0
HFD2_k127_2030170_9 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000136 262.0
HFD2_k127_2051505_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 520.0
HFD2_k127_2051505_1 Peptidase, M16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001132 272.0
HFD2_k127_2051505_2 DinB superfamily - - - 0.000000000000000000000000000000000000008217 147.0
HFD2_k127_2073801_0 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 511.0
HFD2_k127_2073801_1 Domain of unknown function (DUF1858) - - - 0.00000000000000000000000000000000000000001781 167.0
HFD2_k127_2073801_2 conserved protein (DUF2249) - - - 0.00000000000000000000000001914 123.0
HFD2_k127_2073801_3 Pfam:DUF59 - - - 0.0000000000000000004591 89.0
HFD2_k127_2073801_4 conserved protein (DUF2249) - - - 0.0000000000000000005815 99.0
HFD2_k127_2099002_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 1.334e-263 835.0
HFD2_k127_2099002_1 PFAM FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 605.0
HFD2_k127_2099002_10 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000001373 157.0
HFD2_k127_2099002_11 - - - - 0.00000000000000000000000000000000000005568 149.0
HFD2_k127_2099002_12 transcriptional regulator - - - 0.0000000000000000000000000000000000008296 146.0
HFD2_k127_2099002_13 SNARE associated Golgi protein K19302 - 3.6.1.27 0.00000000000000000000000000000000002089 151.0
HFD2_k127_2099002_14 YceI-like domain - - - 0.00000000000000000241 96.0
HFD2_k127_2099002_15 Predicted integral membrane protein (DUF2269) - - - 0.00009032 53.0
HFD2_k127_2099002_2 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 559.0
HFD2_k127_2099002_3 cAMP biosynthetic process K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 506.0
HFD2_k127_2099002_4 amino acid K20265 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0006873,GO:0006885,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0045852,GO:0046942,GO:0046943,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:0098771,GO:1902475,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 469.0
HFD2_k127_2099002_5 Amidase K01426,K19176 - 3.5.1.4,3.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 462.0
HFD2_k127_2099002_6 collagen metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008568 454.0
HFD2_k127_2099002_7 Cysteine-rich domain K11473 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 328.0
HFD2_k127_2099002_8 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000003169 226.0
HFD2_k127_2099002_9 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000005216 204.0
HFD2_k127_2112531_0 transferase activity, transferring glycosyl groups K06984 - 2.4.2.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001975 288.0
HFD2_k127_2112531_1 Protein of unknown function (DUF447) K09154 - - 0.00000000000000000000000000000000000000000000000000000001285 203.0
HFD2_k127_2112531_2 Amino-transferase class IV K00824,K00826 - 2.6.1.21,2.6.1.42 0.000000000000002511 80.0
HFD2_k127_2112531_3 TonB-dependent receptor K02014 - - 0.0000000000001113 78.0
HFD2_k127_2117363_0 Glucose dehydrogenase C-terminus K00008,K05351 - 1.1.1.14,1.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 408.0
HFD2_k127_2117363_1 Nucleoside H+ symporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 402.0
HFD2_k127_2117363_2 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001201 263.0
HFD2_k127_2117363_3 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000009565 213.0
HFD2_k127_2117363_4 Glycosyl hydrolase 36 superfamily, catalytic domain K00702 - 2.4.1.20 0.000000000000000000139 90.0
HFD2_k127_2117363_5 Nucleoside H+ symporter - - - 0.0000000000008448 68.0
HFD2_k127_2127495_0 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 459.0
HFD2_k127_2127495_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 309.0
HFD2_k127_2127495_2 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000007445 226.0
HFD2_k127_2127495_3 Regulatory protein ArsR - - - 0.0000000000000000000000002958 108.0
HFD2_k127_2138090_0 CoA carboxylase activity K01966,K01969 - 2.1.3.15,6.4.1.3,6.4.1.4 4.261e-224 709.0
HFD2_k127_2138090_1 Aminotransferase class I and II K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 505.0
HFD2_k127_2138090_10 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001804 288.0
HFD2_k127_2138090_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000005769 250.0
HFD2_k127_2138090_12 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000005471 203.0
HFD2_k127_2138090_13 transcriptional regulator - - - 0.000000000000000000000000000000001717 139.0
HFD2_k127_2138090_14 DoxX-like family - - - 0.00000000000000000000000000003457 121.0
HFD2_k127_2138090_15 YCII-related domain - - - 0.000000000000000000000000004093 124.0
HFD2_k127_2138090_16 glyoxalase III activity - - - 0.000000000000000000000003213 109.0
HFD2_k127_2138090_17 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000001838 116.0
HFD2_k127_2138090_18 glyoxalase III activity - - - 0.000000000000000000007684 105.0
HFD2_k127_2138090_19 Rhodanese Homology Domain - - - 0.00000000000000000003596 94.0
HFD2_k127_2138090_2 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007129 460.0
HFD2_k127_2138090_20 DinB family - - - 0.00000000000000000009504 100.0
HFD2_k127_2138090_21 Biofilm PGA synthesis protein PgaD - - - 0.000000000000002569 85.0
HFD2_k127_2138090_22 - - - - 0.0003504 43.0
HFD2_k127_2138090_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 389.0
HFD2_k127_2138090_4 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 376.0
HFD2_k127_2138090_5 PFAM Thiamine pyrophosphate K00170,K00187 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 370.0
HFD2_k127_2138090_6 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 331.0
HFD2_k127_2138090_7 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 323.0
HFD2_k127_2138090_8 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 309.0
HFD2_k127_2138090_9 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009114 314.0
HFD2_k127_2173438_0 4 iron, 4 sulfur cluster binding K03737 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 611.0
HFD2_k127_2189148_0 serine-type endopeptidase activity K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 315.0
HFD2_k127_2189148_1 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000163 207.0
HFD2_k127_2189148_2 Activator of hsp90 atpase 1 family protein - - - 0.000000000000000000000000000000000000000002459 164.0
HFD2_k127_2189148_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000941 68.0
HFD2_k127_2195424_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 508.0
HFD2_k127_2195424_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 402.0
HFD2_k127_2195424_10 - - - - 0.00001502 56.0
HFD2_k127_2195424_2 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007244 353.0
HFD2_k127_2195424_3 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 340.0
HFD2_k127_2195424_4 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 347.0
HFD2_k127_2195424_5 ECF sigma factor K03088 - - 0.000000000000000000000000003951 120.0
HFD2_k127_2195424_6 Proton-conducting membrane transporter K12137 - - 0.0000000000000000000000005187 116.0
HFD2_k127_2195424_7 Acetyltransferase (GNAT) domain - - - 0.000000000000007674 85.0
HFD2_k127_2195424_9 - - - - 0.00001415 57.0
HFD2_k127_2200016_0 MMPL family - - - 0.0 1142.0
HFD2_k127_2200016_1 metalloendopeptidase activity K01283 - 3.4.15.1 4.366e-250 786.0
HFD2_k127_2200016_10 WHG domain - - - 0.000000000000000000000000000000000000000000000000000000000000001948 224.0
HFD2_k127_2200016_11 Haloacid dehalogenase-like hydrolase K02566 - - 0.000000000000000000000000000000000000000000000000000000001257 229.0
HFD2_k127_2200016_12 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000000000000000000005461 203.0
HFD2_k127_2200016_13 PFAM PEBP family protein K06910,K07032 - - 0.0000000000000000000000000005279 124.0
HFD2_k127_2200016_14 Aldo/keto reductase family - - - 0.000000000000000000002433 93.0
HFD2_k127_2200016_15 - - - - 0.00000000000000000000269 98.0
HFD2_k127_2200016_16 Lanthionine synthetase C family protein - - - 0.0000000000000000325 93.0
HFD2_k127_2200016_17 COG0671 Membrane-associated phospholipid phosphatase - - - 0.00000000000006977 73.0
HFD2_k127_2200016_2 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 552.0
HFD2_k127_2200016_3 Fe-S oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 406.0
HFD2_k127_2200016_4 Hsp70 protein K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 375.0
HFD2_k127_2200016_5 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 368.0
HFD2_k127_2200016_6 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 361.0
HFD2_k127_2200016_7 Fe-S oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 297.0
HFD2_k127_2200016_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000117 261.0
HFD2_k127_2200016_9 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000002319 259.0
HFD2_k127_2201041_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 1.306e-205 660.0
HFD2_k127_2201041_1 Elongator protein 3, MiaB family, Radical SAM K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 520.0
HFD2_k127_2201041_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 383.0
HFD2_k127_2201041_11 Acyl transferase domain K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 303.0
HFD2_k127_2201041_12 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 293.0
HFD2_k127_2201041_13 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001652 292.0
HFD2_k127_2201041_14 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009212 281.0
HFD2_k127_2201041_15 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000001154 194.0
HFD2_k127_2201041_16 NDK K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000004455 189.0
HFD2_k127_2201041_17 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - 0.00000000000000000000000000000000000000000000004545 183.0
HFD2_k127_2201041_18 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000002591 153.0
HFD2_k127_2201041_19 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000004274 123.0
HFD2_k127_2201041_2 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 526.0
HFD2_k127_2201041_20 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000005043 119.0
HFD2_k127_2201041_21 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000001755 101.0
HFD2_k127_2201041_22 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000005094 83.0
HFD2_k127_2201041_23 23S rRNA-intervening sequence protein - - - 0.00000002218 63.0
HFD2_k127_2201041_3 PFAM Uncharacterised protein family (UPF0182) K09118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 536.0
HFD2_k127_2201041_4 Phosphoglucomutase/phosphomannomutase, C-terminal domain K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 511.0
HFD2_k127_2201041_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458,K14660 - 2.3.1.179,2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 506.0
HFD2_k127_2201041_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 500.0
HFD2_k127_2201041_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 447.0
HFD2_k127_2201041_8 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 411.0
HFD2_k127_2201041_9 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 405.0
HFD2_k127_2241233_0 Amino acid permease - - - 2.344e-245 776.0
HFD2_k127_2241233_1 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 380.0
HFD2_k127_2241233_2 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000007291 218.0
HFD2_k127_2241233_3 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000002471 152.0
HFD2_k127_2241233_4 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system - - - 0.0002055 51.0
HFD2_k127_2251364_0 polygalacturonase activity K01184 - 3.2.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 500.0
HFD2_k127_2251364_1 histidine kinase, dimerisation and phosphoacceptor region K02480 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 428.0
HFD2_k127_2251364_2 pectinesterase activity K01051,K10297 GO:0005575,GO:0005576 3.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 410.0
HFD2_k127_2251364_3 Short-chain Dehydrogenase reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 299.0
HFD2_k127_2251364_4 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005249 284.0
HFD2_k127_2251364_5 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002895 244.0
HFD2_k127_2251364_6 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000005851 159.0
HFD2_k127_2251364_7 LssY C-terminus - - - 0.0000000000000000000000002981 119.0
HFD2_k127_2259259_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 2.416e-252 794.0
HFD2_k127_2259259_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 495.0
HFD2_k127_2259259_2 Threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 336.0
HFD2_k127_2259259_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 325.0
HFD2_k127_2259259_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 307.0
HFD2_k127_227364_0 Glycine betaine K05845 - - 0.00000000000000000000000000000000000000000000000000004958 197.0
HFD2_k127_227364_1 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.0000000000000000000009246 105.0
HFD2_k127_227364_2 Phospholipid methyltransferase - - - 0.0000000000000001237 80.0
HFD2_k127_2285120_0 PFAM Aldehyde dehydrogenase K13877 - 1.2.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 499.0
HFD2_k127_2285120_1 gluconate transmembrane transporter activity K03299 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 494.0
HFD2_k127_2285120_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 467.0
HFD2_k127_2285120_3 aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 387.0
HFD2_k127_2285120_4 Protein of unknown function (DUF421) - - - 0.00000000000000000000000000000000000000000000001274 177.0
HFD2_k127_2285120_5 YceI-like domain - - - 0.0000000000000000000000000000002749 130.0
HFD2_k127_2285120_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000001103 133.0
HFD2_k127_2304398_0 Insulinase (Peptidase family M16) K07263 - - 3.275e-261 838.0
HFD2_k127_2304398_1 Peptidase family M1 domain K01256 - 3.4.11.2 1.322e-225 733.0
HFD2_k127_2304398_10 Serine hydrolase (FSH1) - - - 0.000000000000000000000000000000000000000000000000000593 192.0
HFD2_k127_2304398_11 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000000000000000000000000000000000000000000000009821 195.0
HFD2_k127_2304398_12 Cysteine-rich CPXCG - - - 0.000000000000000000000000001771 113.0
HFD2_k127_2304398_13 cytochrome K05889,K17222 - 1.1.2.6 0.000004109 53.0
HFD2_k127_2304398_2 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 545.0
HFD2_k127_2304398_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 543.0
HFD2_k127_2304398_4 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007505 412.0
HFD2_k127_2304398_5 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008856 377.0
HFD2_k127_2304398_6 Doubled CXXCH motif (Paired_CXXCH_1) K08354 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 331.0
HFD2_k127_2304398_7 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001272 294.0
HFD2_k127_2304398_8 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000001706 250.0
HFD2_k127_2304398_9 Histidine kinase HAMP - - - 0.0000000000000000000000000000000000000000000000000000000000002298 234.0
HFD2_k127_2368979_0 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 295.0
HFD2_k127_2368979_1 Protein of unknown function (DUF3592) - - - 0.000000000000001281 91.0
HFD2_k127_2373047_0 Fibronectin type III-like domain K05349 - 3.2.1.21 8.183e-265 840.0
HFD2_k127_2373047_2 NUDIX domain - - - 0.0000000000000000000000000000000000000008028 154.0
HFD2_k127_2373047_3 PFAM dehydrogenase, E1 component - - - 0.000000000000000000000000000001611 128.0
HFD2_k127_2373047_4 HNH nucleases - - - 0.000000000000000000002678 102.0
HFD2_k127_2403938_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 7.268e-196 625.0
HFD2_k127_2403938_1 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 310.0
HFD2_k127_2403938_2 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001121 274.0
HFD2_k127_2403938_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000001408 251.0
HFD2_k127_2403938_4 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000008425 165.0
HFD2_k127_241139_0 alpha-galactosidase - - - 9.614e-216 690.0
HFD2_k127_241139_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 295.0
HFD2_k127_241139_2 domain protein - - - 0.00000000000000000000000000000000001042 157.0
HFD2_k127_241139_3 Sodium:solute symporter family - - - 0.0000000000000005603 78.0
HFD2_k127_241139_4 Belongs to the glycosyl hydrolase 43 family - - - 0.0000000000000006406 80.0
HFD2_k127_241139_5 PFAM Bacterial Ig-like domain (group 2) - - - 0.0000000000002851 84.0
HFD2_k127_241139_6 - - - - 0.0000001289 62.0
HFD2_k127_2421731_0 carboxylic acid catabolic process K18334 - 4.2.1.68 7.49e-232 723.0
HFD2_k127_2421731_1 ABC transporter K10441 - 3.6.3.17 5.748e-201 643.0
HFD2_k127_2421731_10 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000001709 85.0
HFD2_k127_2421731_2 Periplasmic binding proteins and sugar binding domain of LacI family K10439,K10552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 467.0
HFD2_k127_2421731_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 458.0
HFD2_k127_2421731_4 Branched-chain amino acid transport system / permease component K10440,K10553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 439.0
HFD2_k127_2421731_5 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 357.0
HFD2_k127_2421731_6 amidohydrolase K07046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 327.0
HFD2_k127_2421731_7 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000001154 226.0
HFD2_k127_2421731_8 alcohol dehydrogenase K00008,K00060 - 1.1.1.103,1.1.1.14 0.000000000000000000000000000000000000000000000000000002248 194.0
HFD2_k127_2421731_9 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000004438 142.0
HFD2_k127_242852_0 ATP:guanido phosphotransferase, C-terminal catalytic domain K19405 - 2.7.14.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 439.0
HFD2_k127_242852_1 Clp amino terminal domain, pathogenicity island component K03696 - - 0.0000000000000000000000000000000000000000001329 162.0
HFD2_k127_242852_2 UvrB/uvrC motif K19411 - - 0.00000000000000000000000003693 111.0
HFD2_k127_2515632_0 DEAD/H associated K03724 - - 9.65e-251 824.0
HFD2_k127_2515632_1 PFAM ATP dependent DNA ligase domain protein K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 599.0
HFD2_k127_2515632_2 M61 glycyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 587.0
HFD2_k127_2515632_3 nucleic acid phosphodiester bond hydrolysis K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 473.0
HFD2_k127_2515632_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000007348 231.0
HFD2_k127_2515632_5 ICC-like phosphoesterases K06953 - - 0.0000000000000000000000000000000000000000000000000000000000000004996 226.0
HFD2_k127_2515632_6 - - - - 0.000000000000000000000000000000000000000000000000000004796 194.0
HFD2_k127_2515632_7 Domain of unknown function (DUF892) - - - 0.0000000000000000000000000000000000000000000000000128 184.0
HFD2_k127_2515632_8 Yip1 domain - - - 0.0000001997 62.0
HFD2_k127_2516701_0 cAMP biosynthetic process K01768,K02483 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000006769 274.0
HFD2_k127_2543739_0 - - - - 0.000000000000000000000000000000002776 141.0
HFD2_k127_2543739_1 FdhD/NarQ family K02379 - - 0.0000000000000000000003416 106.0
HFD2_k127_2543739_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.000000004948 62.0
HFD2_k127_2543739_3 bacterial OsmY and nodulation domain - - - 0.00011 54.0
HFD2_k127_2569440_0 Belongs to the TPP enzyme family K00156,K00158 - 1.2.3.3,1.2.5.1 6.372e-266 829.0
HFD2_k127_2569440_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002456 276.0
HFD2_k127_2569440_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000009747 158.0
HFD2_k127_2569440_3 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.000000003017 59.0
HFD2_k127_2594749_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 404.0
HFD2_k127_2594749_1 Pfam Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000002732 210.0
HFD2_k127_2594749_2 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.200,3.5.1.19,6.1.1.16 0.0000000000000000000000000000000000000000000003901 177.0
HFD2_k127_2594749_3 - - - - 0.0000000000000000001736 94.0
HFD2_k127_2608649_0 Methylmalonyl-CoA mutase K01848,K11942 - 5.4.99.13,5.4.99.2 2.518e-235 742.0
HFD2_k127_2608649_1 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 353.0
HFD2_k127_2608649_2 Transporter associated domain - - - 0.0000000000000000000004804 100.0
HFD2_k127_264733_0 Penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 447.0
HFD2_k127_264733_1 N-acetylmuramoyl-L-alanine amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004925 250.0
HFD2_k127_264733_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000003016 195.0
HFD2_k127_264733_4 cyclic nucleotide binding K10914,K21563 - - 0.000000000000000000000000000000000000001453 156.0
HFD2_k127_264733_5 PFAM Uncharacterised BCR, COG1649 - - - 0.00000000000000000000000000000001749 142.0
HFD2_k127_2681276_0 Belongs to the AAA ATPase family K13525 - - 2.662e-306 980.0
HFD2_k127_2681276_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 484.0
HFD2_k127_2681276_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003363 271.0
HFD2_k127_2681276_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000003026 196.0
HFD2_k127_2681276_4 SMART phosphoesterase PA-phosphatase related - - - 0.000000000000000000000000000008562 139.0
HFD2_k127_2686443_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.746e-254 809.0
HFD2_k127_2686443_1 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 3.513e-252 785.0
HFD2_k127_2686443_10 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 336.0
HFD2_k127_2686443_11 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 319.0
HFD2_k127_2686443_12 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000007108 187.0
HFD2_k127_2686443_13 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000004967 194.0
HFD2_k127_2686443_14 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K13799 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25,6.3.2.1 0.000000000000000000000000000000000000000000000001936 187.0
HFD2_k127_2686443_15 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin K14645,K17734 - - 0.00000000000000000000000000000000000000000000003625 188.0
HFD2_k127_2686443_16 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000005183 176.0
HFD2_k127_2686443_17 3-phosphoshikimate 1-carboxyvinyltransferase activity K00800 GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000001158 163.0
HFD2_k127_2686443_18 Biotin-requiring enzyme - - - 0.00000000000000000000000000000000000000002429 160.0
HFD2_k127_2686443_19 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000534 109.0
HFD2_k127_2686443_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 3.833e-213 674.0
HFD2_k127_2686443_20 Putative regulatory protein - - - 0.00000000000000000000002184 104.0
HFD2_k127_2686443_21 Domain of unknown function (DUF1707) - - - 0.00000000000008789 79.0
HFD2_k127_2686443_22 Receptor family ligand binding region - - - 0.0000004955 62.0
HFD2_k127_2686443_23 - - - - 0.000001735 60.0
HFD2_k127_2686443_24 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.000004902 57.0
HFD2_k127_2686443_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008355 540.0
HFD2_k127_2686443_4 CoA carboxylase activity K01968 - 6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009537 518.0
HFD2_k127_2686443_5 Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 497.0
HFD2_k127_2686443_6 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009635 439.0
HFD2_k127_2686443_7 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 382.0
HFD2_k127_2686443_8 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 366.0
HFD2_k127_2686443_9 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 372.0
HFD2_k127_2689895_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1092.0
HFD2_k127_2689895_1 beta-N-acetylhexosaminidase activity - - - 4.313e-239 763.0
HFD2_k127_2689895_10 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008741 302.0
HFD2_k127_2689895_11 PFAM blue (type 1) copper domain protein K00368,K02638 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005736 288.0
HFD2_k127_2689895_12 Belongs to the pseudouridine synthase RsuA family K06178,K06181 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006041 285.0
HFD2_k127_2689895_13 L,D-transpeptidase catalytic domain K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004517 291.0
HFD2_k127_2689895_14 Clp protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004218 251.0
HFD2_k127_2689895_15 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000004354 193.0
HFD2_k127_2689895_16 Fibronectin fibrinogen-binding protein - - - 0.0000000000000000000000000000000000000001875 154.0
HFD2_k127_2689895_17 Putative ABC-transporter type IV - - - 0.000000000000000000000000000000000004382 150.0
HFD2_k127_2689895_18 PFAM Mo-dependent nitrogenase - - - 0.000000000000000000000000000004139 127.0
HFD2_k127_2689895_19 - - - - 0.000000000000000000000002437 108.0
HFD2_k127_2689895_2 Belongs to the glycosyl hydrolase 2 family K01195 - 3.2.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 556.0
HFD2_k127_2689895_20 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000001963 93.0
HFD2_k127_2689895_21 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000009558 87.0
HFD2_k127_2689895_22 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.0000000000000001479 88.0
HFD2_k127_2689895_23 ketosteroid isomerase - - - 0.000000001446 66.0
HFD2_k127_2689895_3 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 540.0
HFD2_k127_2689895_4 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 503.0
HFD2_k127_2689895_5 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 466.0
HFD2_k127_2689895_6 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 428.0
HFD2_k127_2689895_7 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 380.0
HFD2_k127_2689895_8 PFAM Amidohydrolase 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009923 373.0
HFD2_k127_2689895_9 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 335.0
HFD2_k127_2691090_0 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 497.0
HFD2_k127_2691090_1 Heavy metal transport detoxification protein - - - 0.00000000000001948 77.0
HFD2_k127_2691090_2 Amylo-alpha-1,6-glucosidase - - - 0.00003617 53.0
HFD2_k127_2704954_0 Sugar (and other) transporter K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009095 556.0
HFD2_k127_2704954_1 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 364.0
HFD2_k127_2704954_2 Biotin-lipoyl like K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 336.0
HFD2_k127_2704954_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001284 282.0
HFD2_k127_2704954_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000009543 233.0
HFD2_k127_2704954_5 Bacterial transcriptional repressor C-terminal - - - 0.0000000000000000000000000000000000000000000000001148 188.0
HFD2_k127_2704954_6 Outer membrane efflux protein - - - 0.00000000000000000000000000000000001069 154.0
HFD2_k127_2764960_0 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 542.0
HFD2_k127_2764960_1 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000001628 154.0
HFD2_k127_2764960_2 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000001333 111.0
HFD2_k127_2774112_0 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 387.0
HFD2_k127_2774112_1 Thioredoxin - - - 0.000000000000000000000000000000000000000008759 174.0
HFD2_k127_2774112_2 UPF0316 protein - - - 0.00000000000000000000000000000000001435 156.0
HFD2_k127_2774112_3 Aminotransferase class-V - - - 0.0000000000000000000000000000000002459 135.0
HFD2_k127_2787037_0 nitrite reductase [NAD(P)H] activity K00493,K07408,K15762 - 1.14.14.1 3.635e-212 682.0
HFD2_k127_2787037_1 protein catabolic process K03420,K13525,K17681 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 360.0
HFD2_k127_2787037_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001963 283.0
HFD2_k127_2787037_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001026 263.0
HFD2_k127_2787037_4 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000005224 221.0
HFD2_k127_2787037_5 Cadherins are calcium-dependent cell adhesion proteins K05689 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0006633 48.0
HFD2_k127_2792935_0 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001457 290.0
HFD2_k127_2792935_1 PFAM peptidase S58, DmpA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008339 271.0
HFD2_k127_2792935_2 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000008367 183.0
HFD2_k127_2792935_3 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000002898 138.0
HFD2_k127_2792935_4 COG1651 Protein-disulfide isomerase - - - 0.0000000000000000000000000001759 128.0
HFD2_k127_2792935_5 PFAM Vitamin K epoxide reductase - - - 0.0000000000000000000004294 104.0
HFD2_k127_2792935_6 Protein of unknown function (DUF402) K09145 - - 0.000000000000002467 84.0
HFD2_k127_2792935_7 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.00006212 48.0
HFD2_k127_2807858_0 Large extracellular alpha-helical protein K06894 - - 0.0 1746.0
HFD2_k127_2807858_1 penicillin binding K05367 - 2.4.1.129 4.826e-240 768.0
HFD2_k127_2807858_10 With PqqC converts a biosynthetic intermediate to pyrroloquinoline quinone K06138 - - 0.000000000000002332 85.0
HFD2_k127_2807858_11 - - - - 0.0009532 50.0
HFD2_k127_2807858_2 Glycoside hydrolase family 44 K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 561.0
HFD2_k127_2807858_3 radical SAM domain protein K06139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 503.0
HFD2_k127_2807858_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 435.0
HFD2_k127_2807858_5 Beta-lactamase superfamily domain K06136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 321.0
HFD2_k127_2807858_6 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 298.0
HFD2_k127_2807858_7 peroxidase activity K09162 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016701,GO:0016702,GO:0042597,GO:0044464,GO:0050587,GO:0051213,GO:0055114 1.13.11.49 0.0000000000000000000000000000000000000000000000000000000001289 213.0
HFD2_k127_2807858_8 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000001445 167.0
HFD2_k127_2807858_9 iron-sulfur cluster assembly K07400,K13628 - - 0.0000000000000000000000000000000001745 140.0
HFD2_k127_2808107_0 Aldehyde oxidase and xanthine dehydrogenase a b hammerhead K03520,K11177 - 1.17.1.4,1.2.5.3 0.0 1157.0
HFD2_k127_2808107_1 Associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 396.0
HFD2_k127_2808107_2 PFAM YHS domain - - - 0.000000000000000000000000000000000000000000000000000000000001758 229.0
HFD2_k127_2811067_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007791 375.0
HFD2_k127_2811067_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 346.0
HFD2_k127_2811067_2 Metal-independent alpha-mannosidase (GH125) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 317.0
HFD2_k127_2811067_3 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 296.0
HFD2_k127_2811067_5 - - - - 0.0004662 49.0
HFD2_k127_2848025_0 O-acetylhomoserine K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 517.0
HFD2_k127_2848025_1 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 292.0
HFD2_k127_2848025_2 Homoserine dehydrogenase K00003,K12524 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.3,2.7.2.4 0.000000000000000000000000000000000000000000000000000000000001889 223.0
HFD2_k127_2848025_3 - - - - 0.000000000000000000000000000000000696 141.0
HFD2_k127_2859993_0 hydrolase, family 3 K05349 - 3.2.1.21 0.0 1178.0
HFD2_k127_2859993_1 TonB dependent receptor - - - 1.111e-243 787.0
HFD2_k127_2859993_2 MFS/sugar transport protein K03292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005994 515.0
HFD2_k127_2859993_3 Aminotransferase K21572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001916 286.0
HFD2_k127_2887855_0 Aldehyde dehydrogenase family - - - 0.0 1086.0
HFD2_k127_2887855_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 486.0
HFD2_k127_2887855_10 - - - - 0.000000000428 68.0
HFD2_k127_2887855_11 - - - - 0.000003922 57.0
HFD2_k127_2887855_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 300.0
HFD2_k127_2887855_3 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 301.0
HFD2_k127_2887855_4 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001155 291.0
HFD2_k127_2887855_5 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000004203 184.0
HFD2_k127_2887855_6 Calcineurin-like phosphoesterase K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000008977 177.0
HFD2_k127_2887855_7 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.000000000000000000000000000000000000000568 170.0
HFD2_k127_2887855_8 Ham1 family K02428 - 3.6.1.66 0.000000000000000000000000000000000000009318 158.0
HFD2_k127_2887855_9 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000001441 135.0
HFD2_k127_2897153_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 2.398e-255 802.0
HFD2_k127_2897153_1 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 546.0
HFD2_k127_2897153_10 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000004468 152.0
HFD2_k127_2897153_11 - - - - 0.0000000000000001014 94.0
HFD2_k127_2897153_13 - - - - 0.000475 53.0
HFD2_k127_2897153_2 Glycosyl hydrolase-like 10 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 539.0
HFD2_k127_2897153_3 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 434.0
HFD2_k127_2897153_4 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 394.0
HFD2_k127_2897153_5 Dihydroxyacetone kinase family K07030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 361.0
HFD2_k127_2897153_6 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 314.0
HFD2_k127_2897153_7 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 304.0
HFD2_k127_2897153_8 Belongs to the MlaE permease family K02066 - - 0.000000000000000000000000000000000000000000000000000000000000008854 225.0
HFD2_k127_2897153_9 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000000000000000004155 223.0
HFD2_k127_2903621_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1622.0
HFD2_k127_2903621_1 Beta-L-arabinofuranosidase, GH127 K09955 - - 1.363e-303 944.0
HFD2_k127_2903621_10 - - - - 0.00000000000000000000000000000000002513 148.0
HFD2_k127_2903621_11 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000001052 115.0
HFD2_k127_2903621_2 amp-dependent synthetase K01895 - 6.2.1.1 2.459e-236 745.0
HFD2_k127_2903621_3 membrane organization - - - 1.228e-212 703.0
HFD2_k127_2903621_4 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 8.214e-195 647.0
HFD2_k127_2903621_5 Alpha-L-fucosidase K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 618.0
HFD2_k127_2903621_6 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006439 450.0
HFD2_k127_2903621_7 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000001266 174.0
HFD2_k127_2903621_8 SdiA-regulated - - - 0.00000000000000000000000000000000000000000001445 184.0
HFD2_k127_2903621_9 Domain of unknown function (DUF4956) - - - 0.000000000000000000000000000000000000000003176 169.0
HFD2_k127_2906214_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 8.118e-242 777.0
HFD2_k127_2906214_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 384.0
HFD2_k127_2906214_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004784 273.0
HFD2_k127_2906214_3 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000004908 259.0
HFD2_k127_2906214_4 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000001033 229.0
HFD2_k127_2906214_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000002178 169.0
HFD2_k127_2906214_6 Thioredoxin-like - - - 0.00000000000000000000000000000000000002435 150.0
HFD2_k127_2906214_7 Cold shock K03704 - - 0.000000000000000000000000004273 111.0
HFD2_k127_2906214_8 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000001517 115.0
HFD2_k127_2906214_9 PFAM AhpC TSA family K03564 - 1.11.1.15 0.00000000000000000000002798 113.0
HFD2_k127_2906347_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1292.0
HFD2_k127_2906347_1 aminopeptidase N - - - 8.993e-286 894.0
HFD2_k127_2906347_10 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004829 243.0
HFD2_k127_2906347_11 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000007666 228.0
HFD2_k127_2906347_12 Belongs to the amidase family K19176 - 3.5.1.99 0.00000000000000000000000000000000000000000000000000000000003601 220.0
HFD2_k127_2906347_13 Belongs to the amidase family K19176 - 3.5.1.99 0.000000000000000000000000000000000000000001115 174.0
HFD2_k127_2906347_14 helix_turn_helix multiple antibiotic resistance protein K15973 - - 0.000000000000000000000000000000000000000008159 158.0
HFD2_k127_2906347_15 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000005017 155.0
HFD2_k127_2906347_16 Glycosyl hydrolase-like 10 - - - 0.0000000000000000000000000000000000000411 158.0
HFD2_k127_2906347_18 - - - - 0.000000561 59.0
HFD2_k127_2906347_19 SnoaL-like domain - - - 0.00000117 57.0
HFD2_k127_2906347_2 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 530.0
HFD2_k127_2906347_3 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 412.0
HFD2_k127_2906347_4 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008614 364.0
HFD2_k127_2906347_5 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 325.0
HFD2_k127_2906347_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 298.0
HFD2_k127_2906347_7 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002701 278.0
HFD2_k127_2906347_8 glycerophosphodiester transmembrane transport K02026,K08715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006797 298.0
HFD2_k127_2906347_9 Fe-S protein K07140 GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009636,GO:0009987,GO:0019748,GO:0042221,GO:0044237,GO:0044248,GO:0050896,GO:0098754 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001839 264.0
HFD2_k127_2927928_0 Surface antigen K07277,K07278 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 445.0
HFD2_k127_2927928_1 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008805 376.0
HFD2_k127_2927928_2 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000001283 250.0
HFD2_k127_2927928_3 Adenylate cyclase - - - 0.00008354 49.0
HFD2_k127_2928089_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.453e-227 733.0
HFD2_k127_2928089_1 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01761 - 4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 569.0
HFD2_k127_2928089_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000129 275.0
HFD2_k127_2928089_11 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002443 248.0
HFD2_k127_2928089_12 methyltransferase - - - 0.00000000000000000000000000000000000000003935 173.0
HFD2_k127_2928089_13 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000231 165.0
HFD2_k127_2928089_14 SdpI/YhfL protein family - - - 0.00000000000000000000000000000000000002966 155.0
HFD2_k127_2928089_15 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000008229 149.0
HFD2_k127_2928089_16 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000002601 125.0
HFD2_k127_2928089_17 cheY-homologous receiver domain - - - 0.0000000000000000000002261 106.0
HFD2_k127_2928089_18 PFAM regulatory protein ArsR - - - 0.000000000000000000001757 96.0
HFD2_k127_2928089_19 cheY-homologous receiver domain - - - 0.000000000000000005618 90.0
HFD2_k127_2928089_2 Belongs to the glycosyl hydrolase 8 (cellulase D) family K15531 - 3.2.1.156 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000978 464.0
HFD2_k127_2928089_21 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000007323 78.0
HFD2_k127_2928089_22 of nitrite reductase and ring-hydroxylating dioxygenase K05710 - - 0.0000000008822 64.0
HFD2_k127_2928089_23 Domain of unknown function (DUF892) - - - 0.000003431 61.0
HFD2_k127_2928089_24 - - - - 0.0000418 49.0
HFD2_k127_2928089_3 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 462.0
HFD2_k127_2928089_4 Belongs to the glycosyl hydrolase 8 (cellulase D) family K15531 - 3.2.1.156 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005468 425.0
HFD2_k127_2928089_5 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 371.0
HFD2_k127_2928089_6 Domain of unknown function (DUF3471) K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 375.0
HFD2_k127_2928089_7 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 349.0
HFD2_k127_2928089_8 PFAM Histone deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 317.0
HFD2_k127_2928089_9 CorA-like Mg2+ transporter protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004272 287.0
HFD2_k127_2974533_0 Peptidase dimerisation domain K01270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 447.0
HFD2_k127_2974533_1 Sodium Bile acid symporter family K03453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 411.0
HFD2_k127_2974533_10 acetyltransferase - - - 0.00000000000001092 77.0
HFD2_k127_2974533_11 exo-alpha-(2->6)-sialidase activity - - - 0.00000001642 67.0
HFD2_k127_2974533_12 ThiC-associated domain K03147 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.00005963 48.0
HFD2_k127_2974533_13 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000607 56.0
HFD2_k127_2974533_14 Belongs to the acetyltransferase family. ArgA subfamily K00619 - 2.3.1.1 0.0001422 45.0
HFD2_k127_2974533_2 Beta-eliminating lyase K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 399.0
HFD2_k127_2974533_3 Belongs to the glycosyl hydrolase 13 family K07214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 398.0
HFD2_k127_2974533_4 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 310.0
HFD2_k127_2974533_5 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002151 271.0
HFD2_k127_2974533_6 transmembrane transporter activity K03535 - - 0.000000000000000000000000000000000000000000000000000000000000001583 238.0
HFD2_k127_2974533_7 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000001873 196.0
HFD2_k127_2974533_8 Protein of unknown function, DUF480 K09915 - - 0.0000000000000000000000000000000000000000000000003846 185.0
HFD2_k127_2974533_9 COG0739 Membrane proteins related to metalloendopeptidases K21472 - - 0.00000000000000000000000000000000000001038 162.0
HFD2_k127_2979879_0 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 392.0
HFD2_k127_2979879_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 347.0
HFD2_k127_2979879_2 Amidinotransferase K01478 - 3.5.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000001278 278.0
HFD2_k127_2979879_3 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.00000000000000000000000000000000000000000000000000000000000006801 224.0
HFD2_k127_2979879_4 EXOIII K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000125 201.0
HFD2_k127_2979879_5 His Kinase A (phosphoacceptor) domain K20971 - - 0.00000000000008732 82.0
HFD2_k127_298490_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000007997 220.0
HFD2_k127_298490_1 Binds the 23S rRNA K02909 - - 0.00000000000000000000001333 107.0
HFD2_k127_298490_2 Homoserine dehydrogenase, NAD binding domain - - - 0.00000000002853 66.0
HFD2_k127_2991567_0 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 504.0
HFD2_k127_2991567_1 Dihydrolipoyl dehydrogenase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 454.0
HFD2_k127_2991567_10 epimerase K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002054 269.0
HFD2_k127_2991567_11 NIF3 (NGG1p interacting factor 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005143 246.0
HFD2_k127_2991567_12 Putative stress-induced transcription regulator - - - 0.00000000000000000000000000000000000000000669 161.0
HFD2_k127_2991567_13 DinB family - - - 0.0000000000000000000000000000000003354 137.0
HFD2_k127_2991567_14 - - - - 0.00000000000000000000004554 109.0
HFD2_k127_2991567_15 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000009766 86.0
HFD2_k127_2991567_16 COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K10126 - - 0.00000000003807 72.0
HFD2_k127_2991567_18 Polymer-forming cytoskeletal - - - 0.0000001733 59.0
HFD2_k127_2991567_2 Pyruvate dehydrogenase K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 413.0
HFD2_k127_2991567_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 396.0
HFD2_k127_2991567_4 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 373.0
HFD2_k127_2991567_5 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 371.0
HFD2_k127_2991567_6 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 350.0
HFD2_k127_2991567_7 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 335.0
HFD2_k127_2991567_8 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008251 302.0
HFD2_k127_2991567_9 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002147 283.0
HFD2_k127_3002007_0 GMC oxidoreductase - - - 1.75e-263 829.0
HFD2_k127_3002007_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 599.0
HFD2_k127_3002007_2 Gluconate 2-dehydrogenase subunit 3 - - - 0.0000000000000000000000000000000000000000741 175.0
HFD2_k127_3002007_3 mitochondrial respiratory chain complex IV assembly K14998 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944 - 0.00000000000000000000000000000000000001142 156.0
HFD2_k127_3002007_4 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000001483 66.0
HFD2_k127_3002007_5 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000007006 64.0
HFD2_k127_3010503_0 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 311.0
HFD2_k127_3010503_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000539 264.0
HFD2_k127_3010503_2 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000001576 166.0
HFD2_k127_3010503_3 Zincin-like metallopeptidase - - - 0.000000000000000000000009651 112.0
HFD2_k127_3023456_0 Peptidase T2, asparaginase 2 K13051 - 3.4.19.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 402.0
HFD2_k127_3023456_1 Belongs to the phosphatidylserine decarboxylase family K01613 - 4.1.1.65 0.0000003356 53.0
HFD2_k127_3049341_0 Transport of potassium into the cell K03549 - - 3.298e-251 789.0
HFD2_k127_3049341_1 AsmA-like C-terminal region K07289 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 537.0
HFD2_k127_3049341_2 Intracellular protease K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 316.0
HFD2_k127_3049341_3 Domain of unknown function (DUF305) - - - 0.0000000000000000000000000000422 127.0
HFD2_k127_3049341_4 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000004468 63.0
HFD2_k127_3071829_0 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 580.0
HFD2_k127_3071829_1 DNA restriction-modification system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 414.0
HFD2_k127_3071829_2 saccharopine dehydrogenase activity K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000001599 179.0
HFD2_k127_3071829_3 Belongs to the P-Pant transferase superfamily K06133 - - 0.0000000000000000000000000000005131 132.0
HFD2_k127_3071829_4 Insulinase (Peptidase family M16) K07263 - - 0.000000000000004912 77.0
HFD2_k127_3072749_1 Astacin (Peptidase family M12A) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 286.0
HFD2_k127_3072749_10 - K09914 - - 0.00000004449 59.0
HFD2_k127_3072749_2 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000005274 267.0
HFD2_k127_3072749_3 AhpC/TSA family - - - 0.00000000000000000000000000000000000000000000000000000000000000001847 243.0
HFD2_k127_3072749_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000009582 179.0
HFD2_k127_3072749_8 CHAT domain - - - 0.00000000002545 78.0
HFD2_k127_3072749_9 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K20276 - - 0.00000002591 68.0
HFD2_k127_3082587_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 448.0
HFD2_k127_3082587_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007965 397.0
HFD2_k127_3082587_2 PFAM ATP-binding region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005978 289.0
HFD2_k127_3082587_3 Uncharacterized conserved protein (COG2071) K09166 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001141 255.0
HFD2_k127_3082587_4 Cytidine and deoxycytidylate deaminase zinc-binding region - - - 0.000000000000000000000000000000000000000000000000000001726 199.0
HFD2_k127_3082587_5 Domain of unknown function (DUF1508) K09946 - - 0.00000000000000000000000000000000001428 138.0
HFD2_k127_3082587_6 MerR, DNA binding K13639 - - 0.00000000000000000000000004073 114.0
HFD2_k127_3082587_7 N-Acetylmuramoyl-L-alanine amidase - - - 0.0000000000000000000005288 110.0
HFD2_k127_3082587_8 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000001314 77.0
HFD2_k127_3082587_9 Cupin 2, conserved barrel domain protein - - - 0.000005802 53.0
HFD2_k127_3094228_0 phosphorelay signal transduction system K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000003604 286.0
HFD2_k127_3105127_0 cellulose binding - - - 0.0 1123.0
HFD2_k127_3105127_1 Nicastrin K01301 - 3.4.17.21 3.135e-204 662.0
HFD2_k127_3105127_10 Hexapeptide repeat of succinyl-transferase K00661,K03818 - 2.3.1.79 0.000000000000000000000000000000000000000000000000000000000000000001053 234.0
HFD2_k127_3105127_11 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000003585 229.0
HFD2_k127_3105127_12 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K19340 - - 0.000000000000000000000000000000000000000000000000000000001468 216.0
HFD2_k127_3105127_13 Glyoxalase-like domain K08234 - - 0.000000000000000000000000000000000000000000000000000000004262 205.0
HFD2_k127_3105127_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000009 184.0
HFD2_k127_3105127_15 - - - - 0.0000000000000000000000000000000000000000000001876 173.0
HFD2_k127_3105127_16 Putative adhesin - - - 0.00000000000000000000000000000000000000000002183 181.0
HFD2_k127_3105127_17 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000004493 171.0
HFD2_k127_3105127_18 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000216 150.0
HFD2_k127_3105127_19 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000001721 151.0
HFD2_k127_3105127_2 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 3.374e-200 642.0
HFD2_k127_3105127_20 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate - - - 0.000000000000000000000000000000000000005524 160.0
HFD2_k127_3105127_21 NUDIX hydrolase - - - 0.0000000000000000000000000000000000001202 162.0
HFD2_k127_3105127_22 - - - - 0.0000000000000000000000000000005811 124.0
HFD2_k127_3105127_23 SMART chemotaxis sensory transducer, histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000008951 141.0
HFD2_k127_3105127_24 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000002876 130.0
HFD2_k127_3105127_25 - - - - 0.00000000000000000000000000003742 127.0
HFD2_k127_3105127_26 YCII-related domain - - - 0.000000000000000000000000000565 121.0
HFD2_k127_3105127_27 Belongs to the UPF0235 family K09131 - - 0.00000000000000000002221 94.0
HFD2_k127_3105127_28 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.0000000000000000002596 98.0
HFD2_k127_3105127_29 MlaD protein K02067 - - 0.00000000000000000239 98.0
HFD2_k127_3105127_3 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007205 601.0
HFD2_k127_3105127_30 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000144 89.0
HFD2_k127_3105127_31 PFAM nuclear protein SET K07117 - - 0.0000000000036 75.0
HFD2_k127_3105127_32 PBS lyase HEAT-like repeat - - - 0.0000000003648 73.0
HFD2_k127_3105127_33 - - - - 0.00004523 53.0
HFD2_k127_3105127_4 Formiminotransferase domain, N-terminal subdomain K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 595.0
HFD2_k127_3105127_5 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 555.0
HFD2_k127_3105127_6 type II secretion system protein E K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 443.0
HFD2_k127_3105127_7 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 357.0
HFD2_k127_3105127_8 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004449 305.0
HFD2_k127_3105127_9 A G-specific K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005037 289.0
HFD2_k127_3121321_0 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 310.0
HFD2_k127_3121321_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000956 171.0
HFD2_k127_3121321_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000004733 103.0
HFD2_k127_3133233_0 Aldehyde dehydrogenase family K22187 - - 3.464e-246 771.0
HFD2_k127_3133233_1 Bacterial regulatory protein, Fis family - - - 1.696e-200 632.0
HFD2_k127_3133233_10 tRNA processing K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004001 265.0
HFD2_k127_3133233_11 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000001295 244.0
HFD2_k127_3133233_12 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000006648 240.0
HFD2_k127_3133233_13 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000008046 212.0
HFD2_k127_3133233_14 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000005995 210.0
HFD2_k127_3133233_15 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000017 191.0
HFD2_k127_3133233_16 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000001909 190.0
HFD2_k127_3133233_17 Ribosomal protein S9/S16 K02996 - - 0.000000000000000000000000000000000000000001375 160.0
HFD2_k127_3133233_18 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000000000000000000000000000002097 141.0
HFD2_k127_3133233_19 N-Acetylmuramoyl-L-alanine amidase - - - 0.0000000000000000004033 97.0
HFD2_k127_3133233_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.716e-197 633.0
HFD2_k127_3133233_20 amino acid K01999 - - 0.00000000000000005486 93.0
HFD2_k127_3133233_21 zinc metalloprotease K11749 - - 0.000008518 51.0
HFD2_k127_3133233_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 432.0
HFD2_k127_3133233_4 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 427.0
HFD2_k127_3133233_5 Histidine kinase K02282,K02482,K03557 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 401.0
HFD2_k127_3133233_6 Ribosomal protein S2 K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 332.0
HFD2_k127_3133233_7 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 319.0
HFD2_k127_3133233_8 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 305.0
HFD2_k127_3133233_9 NmrA-like family K19267 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003266 285.0
HFD2_k127_3154080_1 TonB dependent receptor K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000003002 257.0
HFD2_k127_3154080_3 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000004733 208.0
HFD2_k127_3187614_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 9.195e-255 797.0
HFD2_k127_3187614_1 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 389.0
HFD2_k127_3187614_10 Lipopolysaccharide-assembly, LptC-related - - - 0.00000000000000000006341 98.0
HFD2_k127_3187614_2 SIS domain K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 368.0
HFD2_k127_3187614_3 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 317.0
HFD2_k127_3187614_4 DAHP synthetase I family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000513 296.0
HFD2_k127_3187614_5 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000001131 266.0
HFD2_k127_3187614_6 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000002331 235.0
HFD2_k127_3187614_7 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000004474 175.0
HFD2_k127_3187614_9 - - - - 0.0000000000000000000001723 113.0
HFD2_k127_3198823_0 ACT domain K12524 - 1.1.1.3,2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 611.0
HFD2_k127_3198823_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 460.0
HFD2_k127_3198823_2 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 312.0
HFD2_k127_3198823_3 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000009686 241.0
HFD2_k127_3198823_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001057 238.0
HFD2_k127_3198823_5 Glyoxalase-like domain K05606 - 5.1.99.1 0.0000000000000000000000000000000000000007227 152.0
HFD2_k127_3198823_6 - - - - 0.00004073 54.0
HFD2_k127_3221950_0 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 352.0
HFD2_k127_3221950_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009078 337.0
HFD2_k127_3221950_2 AcrB/AcrD/AcrF family K07787,K15726 - - 0.000000000000000000000000001096 113.0
HFD2_k127_3257443_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009894 537.0
HFD2_k127_3257443_1 Glucose inhibited division protein A K21401 - 1.3.99.38 0.000000000000000000000000000000000000000000000000000001037 211.0
HFD2_k127_3257443_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000003207 164.0
HFD2_k127_3257443_3 YceI-like domain - - - 0.00004644 54.0
HFD2_k127_3257470_0 Glycosyl transferase family 21 K22278 - 3.5.1.104 0.0 1101.0
HFD2_k127_3257470_1 isocitrate dehydrogenase activity K00031 GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000758 585.0
HFD2_k127_3257470_10 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000002489 192.0
HFD2_k127_3257470_11 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000006162 183.0
HFD2_k127_3257470_12 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.00000000000000000000000000000000000000000000001783 181.0
HFD2_k127_3257470_13 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000239 179.0
HFD2_k127_3257470_14 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000044 173.0
HFD2_k127_3257470_15 Telomere recombination K07566 - 2.7.7.87 0.000000000000000000000000000000000000002292 166.0
HFD2_k127_3257470_16 Low molecular weight phosphatase family K01104 - 3.1.3.48 0.000000000000000000000000000000000003784 145.0
HFD2_k127_3257470_17 Domain of unknown function (DUF4142) K08995 - - 0.000000000000000000000000000001035 129.0
HFD2_k127_3257470_18 TonB-dependent Receptor Plug Domain - - - 0.000000000000000000000000004613 128.0
HFD2_k127_3257470_19 1,4-alpha-glucan branching enzyme activity K00700 - 2.4.1.18 0.000000000000000000002503 106.0
HFD2_k127_3257470_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008486 565.0
HFD2_k127_3257470_20 Cupredoxin-like domain - - - 0.00000000000000004746 84.0
HFD2_k127_3257470_21 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits - - - 0.0000000000000002712 84.0
HFD2_k127_3257470_22 - - - - 0.00000000001178 74.0
HFD2_k127_3257470_23 - - - - 0.00000004177 65.0
HFD2_k127_3257470_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 465.0
HFD2_k127_3257470_4 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 438.0
HFD2_k127_3257470_5 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 435.0
HFD2_k127_3257470_6 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 411.0
HFD2_k127_3257470_7 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000005261 223.0
HFD2_k127_3257470_8 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000569 211.0
HFD2_k127_3257470_9 virulence factor family protein - - - 0.000000000000000000000000000000000000000000000000002297 194.0
HFD2_k127_3267185_0 PFAM magnesium chelatase ChlI subunit K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 567.0
HFD2_k127_3267185_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 353.0
HFD2_k127_3267185_10 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000001877 225.0
HFD2_k127_3267185_11 creatininase K01470,K22232 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000005115 205.0
HFD2_k127_3267185_12 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000006274 186.0
HFD2_k127_3267185_13 - - - - 0.000000000000000000000000000009117 128.0
HFD2_k127_3267185_2 - K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 348.0
HFD2_k127_3267185_3 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 340.0
HFD2_k127_3267185_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 356.0
HFD2_k127_3267185_5 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 321.0
HFD2_k127_3267185_6 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 318.0
HFD2_k127_3267185_7 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 317.0
HFD2_k127_3267185_8 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 307.0
HFD2_k127_3267185_9 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005544 252.0
HFD2_k127_3329814_0 ABC transporter K06020 - 3.6.3.25 3.705e-254 811.0
HFD2_k127_3329814_1 PFAM Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 482.0
HFD2_k127_3329814_2 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 477.0
HFD2_k127_3329814_3 Sir2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 314.0
HFD2_k127_3329814_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 329.0
HFD2_k127_3329814_5 AntiSigma factor - - - 0.00000000000000000000000000000000000008611 156.0
HFD2_k127_3329814_6 'TIGRFAM RNA polymerase sigma factor, sigma-70 family' K03088 - - 0.0000000000000000000000000000000000001807 147.0
HFD2_k127_3346450_0 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0044237 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 349.0
HFD2_k127_3346450_1 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 310.0
HFD2_k127_3346450_2 NUDIX domain - - - 0.00000000000000000000000000000000000000000163 167.0
HFD2_k127_3346450_3 Putative adhesin - - - 0.0000000000001995 82.0
HFD2_k127_3346450_4 - - - - 0.000004131 53.0
HFD2_k127_3348818_0 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 342.0
HFD2_k127_3348818_1 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K07106,K09001 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 2.7.1.170,4.2.1.126 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009244 327.0
HFD2_k127_3348818_2 Glycosyl hydrolase family 3 N terminal domain K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 331.0
HFD2_k127_3348818_3 peptidase dimerisation domain protein K01436 - - 0.000000000000000000000000000000000000000000000000001902 188.0
HFD2_k127_3361990_0 glycoside hydrolase family 38 K01191 - 3.2.1.24 0.0 1138.0
HFD2_k127_3361990_1 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006119 542.0
HFD2_k127_3361990_2 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000142 293.0
HFD2_k127_3361990_3 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005801 302.0
HFD2_k127_3361990_4 JAB/MPN domain K21140 - 3.13.1.6 0.0000000000000000009175 98.0
HFD2_k127_3363827_0 asparagine K01953 - 6.3.5.4 2.231e-194 627.0
HFD2_k127_3363827_1 Chain length determinant protein K16554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 484.0
HFD2_k127_3363827_2 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 422.0
HFD2_k127_3363827_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 359.0
HFD2_k127_3363827_4 xylanase chitin deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002599 289.0
HFD2_k127_3363827_5 Protein involved in cellulose biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000688 269.0
HFD2_k127_3363827_6 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000922 234.0
HFD2_k127_3363827_7 polysaccharide export - - - 0.0000000000000000000000000002407 131.0
HFD2_k127_3363827_8 Glycosyl transferase 4-like - - - 0.0000000003483 73.0
HFD2_k127_3367232_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 7.247e-284 890.0
HFD2_k127_3367232_1 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002242 270.0
HFD2_k127_3367232_2 TipAS antibiotic-recognition domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009691 248.0
HFD2_k127_3367232_3 Ergosterol biosynthesis ERG4/ERG24 family - - - 0.000000000000000000000000000000000000000000000000000002363 199.0
HFD2_k127_3367232_5 - - - - 0.00000000000000000000000000001606 132.0
HFD2_k127_3367232_6 TonB-dependent receptor - - - 0.0000000000002384 78.0
HFD2_k127_3367232_7 YoaP-like - - - 0.0000002301 62.0
HFD2_k127_3391855_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 539.0
HFD2_k127_3391855_1 HELICc2 K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 502.0
HFD2_k127_3391855_2 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 329.0
HFD2_k127_3391855_3 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 296.0
HFD2_k127_3391855_4 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000002074 250.0
HFD2_k127_3391855_5 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000000004092 151.0
HFD2_k127_3391855_6 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000000000000000001491 128.0
HFD2_k127_3391855_7 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division K20543 - - 0.0000000000000000000897 105.0
HFD2_k127_3391855_8 - - - - 0.00000000001311 72.0
HFD2_k127_3410550_0 Belongs to the acetokinase family K00929 - 2.7.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007531 379.0
HFD2_k127_3410550_1 SPTR Beta-galactosidase I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000981 359.0
HFD2_k127_3410550_10 TIGRFAM regulatory protein, FmdB - - - 0.00000302 56.0
HFD2_k127_3410550_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000495 303.0
HFD2_k127_3410550_3 PFAM Phosphate acetyl butaryl transferase K00634 - 2.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000009915 250.0
HFD2_k127_3410550_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00123,K12527,K15022 - 1.17.1.10,1.17.1.9,1.97.1.9 0.00000000000000000000000000000000000000000000000000000000000000003384 249.0
HFD2_k127_3410550_5 Peptidase family S41 - - - 0.0000000000000000000000000000000000000000000002065 182.0
HFD2_k127_3410550_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000002968 139.0
HFD2_k127_3410550_7 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000005691 147.0
HFD2_k127_3410550_8 Protein of unknown function (DUF445) - - - 0.00000000000000000000009411 98.0
HFD2_k127_3410550_9 Regulatory protein, FmdB family - - - 0.0000001807 55.0
HFD2_k127_3449863_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 8.74e-213 672.0
HFD2_k127_3449863_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000002155 223.0
HFD2_k127_3449863_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000003734 153.0
HFD2_k127_3449863_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.000000000000000000002439 101.0
HFD2_k127_348997_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005077 562.0
HFD2_k127_348997_1 Glycosyl hydrolases family 16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005656 408.0
HFD2_k127_348997_2 PFAM YdjC family protein K03478 - 3.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003341 284.0
HFD2_k127_348997_3 DinB family - - - 0.0000000000000000000000000000000000000004848 157.0
HFD2_k127_348997_4 Nucleoside recognition K06373 - - 0.00000000000000000000000000000001836 133.0
HFD2_k127_348997_5 acetyltransferase - - - 0.00000000001788 72.0
HFD2_k127_349231_0 Glycosyl hydrolase-like 10 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008601 508.0
HFD2_k127_349231_1 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 344.0
HFD2_k127_349231_2 transferase activity, transferring glycosyl groups K06984 - 2.4.2.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005573 275.0
HFD2_k127_349231_3 PFAM OsmC family protein - - - 0.00000000000000000000000000000000000000000000000000000003399 202.0
HFD2_k127_349231_4 Protein of unknown function (DUF447) K09154 - - 0.0000000000000000000000000000000000000000000000000001562 191.0
HFD2_k127_349231_5 Aminotransferase K00826 - 2.6.1.42 0.00000000000000005729 84.0
HFD2_k127_3504706_0 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 317.0
HFD2_k127_3504706_1 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006332 254.0
HFD2_k127_3504706_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.000000000000000000000000000000000000000000000000000000000000000000002124 242.0
HFD2_k127_3504706_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000008474 223.0
HFD2_k127_3504706_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000002373 166.0
HFD2_k127_3504706_5 Domain of unknown function (DUF3597) - - - 0.00000000000000000000000000000000000000000009692 162.0
HFD2_k127_3508527_0 peptidase S9B dipeptidylpeptidase IV domain protein - - - 1.198e-308 964.0
HFD2_k127_3508527_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009762 354.0
HFD2_k127_3508527_2 DinB family - - - 0.0000000000000000000000000000000000000000000000000000005517 197.0
HFD2_k127_3508527_3 Acetyltransferase (GNAT) family K18815 - 2.3.1.82 0.0000000000000000000000000000000001373 142.0
HFD2_k127_3508527_4 protein-S-isoprenylcysteine methyltransferase - - - 0.000000000000000000000003326 109.0
HFD2_k127_3508527_5 Domain of unknown function (DUF1330) - - - 0.0000000000000000253 94.0
HFD2_k127_3511894_0 Two component regulator propeller K17763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 362.0
HFD2_k127_3512601_0 Putative glutamine amidotransferase - - - 2.384e-197 639.0
HFD2_k127_3512601_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009209 529.0
HFD2_k127_3512601_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 445.0
HFD2_k127_3512601_3 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 332.0
HFD2_k127_3512601_4 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000004584 193.0
HFD2_k127_3512601_5 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000001955 205.0
HFD2_k127_3512601_6 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000000002579 199.0
HFD2_k127_3512601_7 Aerotolerance regulator N-terminal - - - 0.00000000000000000001119 102.0
HFD2_k127_3512781_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 3.113e-291 918.0
HFD2_k127_3512781_1 cellulose binding - - - 2.153e-215 685.0
HFD2_k127_3512781_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 602.0
HFD2_k127_3512781_3 Membrane dipeptidase (Peptidase family M19) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007667 306.0
HFD2_k127_3512781_4 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001132 286.0
HFD2_k127_3512781_5 FCD - - - 0.000000000000000000000000000000000000000000000000000000002504 210.0
HFD2_k127_3522085_0 56kDa selenium binding protein (SBP56) K17285 - - 2.038e-226 711.0
HFD2_k127_3522085_1 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 447.0
HFD2_k127_3522085_2 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 423.0
HFD2_k127_3522085_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000009365 254.0
HFD2_k127_3522085_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000127 182.0
HFD2_k127_3522085_5 - - - - 0.0000000000000000000000000000000000000000000001584 179.0
HFD2_k127_3522085_6 trisaccharide binding - - - 0.00000000000000000000000000001785 121.0
HFD2_k127_3522085_7 Alternative locus ID K10697 - - 0.00000000000000000000003717 107.0
HFD2_k127_3522085_8 Electron transport protein SCO1 SenC K07152 - - 0.000000005381 66.0
HFD2_k127_3522085_9 - - - - 0.0006436 46.0
HFD2_k127_3543840_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1514.0
HFD2_k127_3543840_1 repeat-containing protein - - - 0.00000006055 64.0
HFD2_k127_3558147_0 Beta-L-arabinofuranosidase, GH127 K09955 - - 6.082e-315 985.0
HFD2_k127_3558147_1 PFAM TonB-dependent Receptor Plug - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005933 533.0
HFD2_k127_3572717_0 Dipeptidyl carboxypeptidase K01284 - 3.4.15.5 9.907e-275 869.0
HFD2_k127_3572717_1 PFAM amino acid permease-associated region K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005712 419.0
HFD2_k127_3572717_2 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000006705 246.0
HFD2_k127_3572717_3 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000003486 184.0
HFD2_k127_3572717_4 Glycerate kinase family K00865 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.1.165 0.000000000000000000000000008705 126.0
HFD2_k127_3572717_5 MlaD protein K02067 - - 0.0000000000000002806 89.0
HFD2_k127_3572717_6 PRC-barrel domain - - - 0.00000005952 65.0
HFD2_k127_3588160_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 3.339e-224 707.0
HFD2_k127_3588160_1 amine dehydrogenase activity K17285 - - 1.584e-210 656.0
HFD2_k127_3588160_10 - - - - 0.000000000000000000000000000000000000000000000000000002329 198.0
HFD2_k127_3588160_11 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000183 162.0
HFD2_k127_3588160_13 acetyltransferase - - - 0.00000000000000000000000000005539 135.0
HFD2_k127_3588160_15 Protein of unknown function (DUF3455) - - - 0.000000000000000000000005439 110.0
HFD2_k127_3588160_16 cellulase activity - - - 0.0000000000000001799 95.0
HFD2_k127_3588160_2 PFAM Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 9.019e-200 662.0
HFD2_k127_3588160_3 CHAT domain - - - 5.334e-194 642.0
HFD2_k127_3588160_4 H( )-stimulated, divalent metal cation uptake system K03322 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 552.0
HFD2_k127_3588160_5 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 473.0
HFD2_k127_3588160_6 (ABC) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 341.0
HFD2_k127_3588160_7 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.000000000000000000000000000000000000000000000000000000000000000008245 235.0
HFD2_k127_3588160_8 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000002981 230.0
HFD2_k127_3588160_9 - - - - 0.0000000000000000000000000000000000000000000000000000000434 201.0
HFD2_k127_364942_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 3.752e-256 823.0
HFD2_k127_364942_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009672 486.0
HFD2_k127_364942_10 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000001052 137.0
HFD2_k127_364942_11 response regulator K07714 - - 0.00000000000000000000000000005561 118.0
HFD2_k127_364942_12 - - - - 0.0000000000000000000000000003161 129.0
HFD2_k127_364942_13 - - - - 0.0000000000000001595 94.0
HFD2_k127_364942_14 - - - - 0.0000000003645 72.0
HFD2_k127_364942_15 assembly protein PilO K02664 - - 0.000000002381 66.0
HFD2_k127_364942_16 - - - - 0.00000008272 60.0
HFD2_k127_364942_2 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 374.0
HFD2_k127_364942_3 AMIN domain K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 363.0
HFD2_k127_364942_4 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 332.0
HFD2_k127_364942_5 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 303.0
HFD2_k127_364942_6 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000382 241.0
HFD2_k127_364942_7 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000001294 194.0
HFD2_k127_364942_8 Fimbrial assembly protein (PilN) - - - 0.000000000000000000000000000000000000000913 158.0
HFD2_k127_364942_9 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000005973 166.0
HFD2_k127_3653354_0 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 299.0
HFD2_k127_3653354_1 Peptidoglycan-synthase activator LpoB - - - 0.000000000000000000000000000000000000000000000000000000000194 212.0
HFD2_k127_3653354_2 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000001549 209.0
HFD2_k127_3653354_3 Phosphoribosyl transferase domain K07101 - - 0.000000000000000000000000000000000000000000009177 169.0
HFD2_k127_3653354_4 Alpha beta hydrolase - - - 0.0000000000000000000000004751 115.0
HFD2_k127_3653354_5 PFAM Sporulation and spore germination - - - 0.00000000000000000004648 103.0
HFD2_k127_3664770_0 PFAM ASPIC and UnbV - - - 7.545e-275 883.0
HFD2_k127_3664770_1 Elongation factor G, domain IV K02355 - - 3.463e-221 706.0
HFD2_k127_3664770_2 Domain in cystathionine beta-synthase and other proteins. K01697 - 4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008406 613.0
HFD2_k127_3664770_3 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008735 458.0
HFD2_k127_3664770_4 Belongs to the D-alanine--D-alanine ligase family K01921 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009093 359.0
HFD2_k127_3664770_5 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 291.0
HFD2_k127_3664770_6 Rhomboid family - - - 0.000000000000000000000000000000000000000000001444 176.0
HFD2_k127_3664770_7 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000000004527 156.0
HFD2_k127_3664770_8 Periplasmic component of the Tol biopolymer transport system K03641 - - 0.000000000000002285 91.0
HFD2_k127_3664770_9 TIGRFAM TonB family C-terminal domain K03832 - - 0.00008808 53.0
HFD2_k127_3678359_0 oxidoreductase activity K00274 - 1.4.3.4 8.476e-287 888.0
HFD2_k127_3678359_1 heme-copper terminal oxidase activity K02274 - 1.9.3.1 1.332e-194 620.0
HFD2_k127_3678359_2 Glycosyl hydrolase family 20, domain 2 K12373 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 509.0
HFD2_k127_3678359_3 Fibronectin type III-like domain K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 314.0
HFD2_k127_3678359_4 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004103 268.0
HFD2_k127_3678359_5 cytochrome c oxidase (Subunit II) - - - 0.0000000000000000000000000000000000000000000000000000000001749 210.0
HFD2_k127_3678359_6 2 iron, 2 sulfur cluster binding K13643 - - 0.00000000000000000000000000001525 122.0
HFD2_k127_3678359_7 2 iron, 2 sulfur cluster binding K13643 - - 0.0000000000000000001366 104.0
HFD2_k127_3678359_8 - - - - 0.00000001531 66.0
HFD2_k127_3678359_9 Cytochrome C oxidase subunit I K02274 - 1.9.3.1 0.00008055 49.0
HFD2_k127_3680163_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000784 486.0
HFD2_k127_3680163_1 Anthranilate synthase component I, N terminal region K01657,K01665,K13950 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 423.0
HFD2_k127_3680163_2 PFAM Glutamine amidotransferase class-I K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000001235 263.0
HFD2_k127_3680163_3 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000000000000000001052 184.0
HFD2_k127_3680163_4 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00826 - 2.6.1.42 0.00000000000000000000000000000000004817 144.0
HFD2_k127_3745155_0 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008673 429.0
HFD2_k127_3745155_1 phosphorelay sensor kinase activity K07711,K14980,K18143 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000238 227.0
HFD2_k127_3747767_0 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 307.0
HFD2_k127_3747767_1 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000000000000003904 198.0
HFD2_k127_3747767_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000003143 193.0
HFD2_k127_3747767_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000003388 146.0
HFD2_k127_3747767_4 DNA-templated transcription, termination K03628 - - 0.0000000000000000000000000001148 117.0
HFD2_k127_3747767_6 - - - - 0.000005669 59.0
HFD2_k127_3754911_0 UTP--glucose-1-phosphate uridylyltransferase - - - 0.0 1039.0
HFD2_k127_3754911_1 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005521 359.0
HFD2_k127_3779060_0 DNA topoisomerase II activity K02469 - 5.99.1.3 7.388e-274 867.0
HFD2_k127_3779060_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 409.0
HFD2_k127_3779060_2 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000007576 189.0
HFD2_k127_3779060_3 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000004603 179.0
HFD2_k127_3779060_4 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000009796 174.0
HFD2_k127_3779060_5 Iron-sulfur cluster assembly protein - - - 0.00000000000000000000000152 106.0
HFD2_k127_3779060_6 chaperone-mediated protein folding - - - 0.00000000000000009176 82.0
HFD2_k127_3779060_7 Rdx family K07401 - - 0.000000008464 58.0
HFD2_k127_3779060_8 Putative zinc-finger - GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.000003062 52.0
HFD2_k127_3779060_9 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00001496 58.0
HFD2_k127_3785445_0 radical SAM domain protein - - - 1.598e-207 657.0
HFD2_k127_3785445_1 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 456.0
HFD2_k127_3785445_2 Glycosyl transferase family 2 K11936,K14666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007248 398.0
HFD2_k127_3785445_3 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 306.0
HFD2_k127_3785445_4 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007423 269.0
HFD2_k127_3785445_5 phosphorelay signal transduction system K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000009792 240.0
HFD2_k127_3785445_6 Bacterial regulatory proteins, luxR family - - - 0.000000000000000000000000000006548 123.0
HFD2_k127_3785445_7 metal cluster binding - - - 0.00000004154 61.0
HFD2_k127_3789127_0 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000001652 109.0
HFD2_k127_3790302_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 488.0
HFD2_k127_3790302_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 332.0
HFD2_k127_3790302_2 Phage integrase, N-terminal SAM-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001208 271.0
HFD2_k127_3790302_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000004924 194.0
HFD2_k127_3790302_4 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000001206 184.0
HFD2_k127_3790302_5 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.000000000000000000000000000001853 124.0
HFD2_k127_3798651_0 Cytochrome C oxidase, cbb3-type, subunit III K19713 - 1.8.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 358.0
HFD2_k127_3798651_1 transcriptional regulator - - - 0.0000000000000000001061 98.0
HFD2_k127_3798651_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K17225 - - 0.0000001893 62.0
HFD2_k127_3805118_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 5.3e-242 763.0
HFD2_k127_3805118_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 1.226e-231 745.0
HFD2_k127_3805118_10 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.0000000000000000000000000000000000000000000000004582 186.0
HFD2_k127_3805118_11 Enoyl-CoA hydratase carnithine racemase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000023 173.0
HFD2_k127_3805118_12 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.0000000000000000000000000000004617 137.0
HFD2_k127_3805118_13 Thiol-disulfide isomerase-like thioredoxin K02199 - - 0.000000000000000000000000000003778 132.0
HFD2_k127_3805118_14 carbon dioxide binding K04653,K04654 - - 0.0000000000000000000000000002122 121.0
HFD2_k127_3805118_15 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000007216 126.0
HFD2_k127_3805118_16 subunit of a heme lyase K02198,K02200 - - 0.00000000000000000031 100.0
HFD2_k127_3805118_17 heat shock protein binding - - - 0.0000005703 61.0
HFD2_k127_3805118_18 nickel cation binding K04651,K19640 - - 0.00002397 49.0
HFD2_k127_3805118_2 Cytochrome C assembly protein K02198,K04016 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - 1.664e-196 632.0
HFD2_k127_3805118_3 Hydrogenase formation hypA family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 496.0
HFD2_k127_3805118_4 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 447.0
HFD2_k127_3805118_5 small subunit K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 434.0
HFD2_k127_3805118_6 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07713,K07714,K19641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 415.0
HFD2_k127_3805118_7 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000001706 228.0
HFD2_k127_3805118_8 Histidine kinase K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000001134 236.0
HFD2_k127_3805118_9 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000001981 208.0
HFD2_k127_381154_0 Peptidase family M1 domain - - - 7.783e-213 679.0
HFD2_k127_381154_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 381.0
HFD2_k127_381154_2 cellular manganese ion homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 348.0
HFD2_k127_381154_3 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000667 280.0
HFD2_k127_381154_4 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000004853 74.0
HFD2_k127_381154_5 Sugar (and other) transporter K03446 - - 0.0000001106 56.0
HFD2_k127_3862002_0 hydrolase family, 3 K05349 - 3.2.1.21 0.0 1221.0
HFD2_k127_3862002_1 Belongs to the glycosyl hydrolase 43 family - - - 1.202e-287 893.0
HFD2_k127_3862002_10 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000002282 269.0
HFD2_k127_3862002_11 PFAM YdjC family protein K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000001326 256.0
HFD2_k127_3862002_12 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000003321 214.0
HFD2_k127_3862002_13 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000003933 213.0
HFD2_k127_3862002_14 Thioredoxin-like domain K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000003821 192.0
HFD2_k127_3862002_15 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000002923 180.0
HFD2_k127_3862002_16 Glycosyl hydrolase-like 10 - - - 0.00000000000000000000000000000000001477 151.0
HFD2_k127_3862002_17 YCII-related domain - - - 0.000000000000000000000000000002777 124.0
HFD2_k127_3862002_18 - - - - 0.000000000000000001484 92.0
HFD2_k127_3862002_19 PFAM AMP-dependent synthetase and ligase K18687 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 6.2.1.41 0.00000134 55.0
HFD2_k127_3862002_2 - - - - 7.483e-259 813.0
HFD2_k127_3862002_21 transcriptional K22295 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.00001021 56.0
HFD2_k127_3862002_22 Domain of unknown function (DUF4440) - - - 0.00001614 53.0
HFD2_k127_3862002_3 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 568.0
HFD2_k127_3862002_4 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 502.0
HFD2_k127_3862002_5 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006734 446.0
HFD2_k127_3862002_6 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 369.0
HFD2_k127_3862002_7 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 304.0
HFD2_k127_3862002_8 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 300.0
HFD2_k127_3862002_9 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001554 286.0
HFD2_k127_3897279_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 612.0
HFD2_k127_3897279_1 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 561.0
HFD2_k127_3897279_2 Aminoacyl tRNA synthetase class II, N-terminal domain K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 419.0
HFD2_k127_3897279_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006608 349.0
HFD2_k127_3897279_4 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 329.0
HFD2_k127_3897279_5 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000005789 70.0
HFD2_k127_3897279_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000634 58.0
HFD2_k127_3926055_0 lipase activity K15349 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 457.0
HFD2_k127_3949468_0 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 380.0
HFD2_k127_3949468_1 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 308.0
HFD2_k127_3949468_2 phosphatidate phosphatase activity K00901,K01096,K19302 - 2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.000000000000000000000000000000000000000000121 173.0
HFD2_k127_3949468_3 Transglycosylase SLT domain - - - 0.0000000000000000000000001249 119.0
HFD2_k127_3949468_4 CAAX protease self-immunity K07052 - - 0.00000000002456 75.0
HFD2_k127_3959947_0 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 5.802e-227 734.0
HFD2_k127_3959947_1 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 323.0
HFD2_k127_3959947_2 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000001421 185.0
HFD2_k127_3959947_3 HicB family - - - 0.00000000000000000000000000000002673 130.0
HFD2_k127_3959947_4 - - - - 0.0000000000000000009512 95.0
HFD2_k127_4055606_0 PFAM ADP-ribosylation Crystallin J1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 426.0
HFD2_k127_4055606_1 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000001218 298.0
HFD2_k127_4055606_2 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003674 273.0
HFD2_k127_4055606_3 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000004295 203.0
HFD2_k127_4055606_4 COG3857 ATP-dependent nuclease, subunit B K16899 - 3.6.4.12 0.00000000000000000000000000000000000001765 166.0
HFD2_k127_4055606_5 phosphatase - - - 0.00000000000000000000000000000000001006 147.0
HFD2_k127_4055606_6 Putative bacterial sensory transduction regulator - - - 0.00000000000001261 87.0
HFD2_k127_4055606_7 ferredoxin-NADP+ reductase activity - - - 0.0001385 46.0
HFD2_k127_407281_0 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 3.803e-279 884.0
HFD2_k127_407281_1 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 4.646e-215 677.0
HFD2_k127_407281_10 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001612 243.0
HFD2_k127_407281_11 - - - - 0.00000000000000000000000000000000000000000000000000000002047 205.0
HFD2_k127_407281_12 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000000000000000000001821 224.0
HFD2_k127_407281_13 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000002147 200.0
HFD2_k127_407281_14 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000006906 163.0
HFD2_k127_407281_15 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000000000005659 149.0
HFD2_k127_407281_16 ABC transporter K06861 - - 0.000000000000000000000000000000000003495 138.0
HFD2_k127_407281_17 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000007212 151.0
HFD2_k127_407281_18 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000001708 135.0
HFD2_k127_407281_19 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000001266 112.0
HFD2_k127_407281_2 Glycosyl hydrolases family 15 - - - 4.356e-199 649.0
HFD2_k127_407281_20 Lysylphosphatidylglycerol synthase TM region K07027,K20468 - - 0.0000000000000005136 89.0
HFD2_k127_407281_21 - - - - 0.000000000001911 80.0
HFD2_k127_407281_22 helix_turn_helix gluconate operon transcriptional repressor - - - 0.0000004233 64.0
HFD2_k127_407281_23 Tetratricopeptide repeat-like domain - - - 0.000003206 57.0
HFD2_k127_407281_3 PQQ enzyme repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 480.0
HFD2_k127_407281_4 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 364.0
HFD2_k127_407281_5 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 362.0
HFD2_k127_407281_6 Bacterial membrane protein YfhO - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009954 331.0
HFD2_k127_407281_7 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 293.0
HFD2_k127_407281_8 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001537 296.0
HFD2_k127_407281_9 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006351 277.0
HFD2_k127_4129534_0 TonB-linked outer membrane protein, SusC RagA family - - - 0.0 1236.0
HFD2_k127_4129534_1 Glycosyl hydrolases family 2, TIM barrel domain K01190,K01195 GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005575,GO:0005975,GO:0005984,GO:0005988,GO:0005990,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009341,GO:0009987,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0032991,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0071704,GO:1901575,GO:1902494 3.2.1.23,3.2.1.31 1.433e-307 977.0
HFD2_k127_4129534_10 purine nucleotide biosynthetic process K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 409.0
HFD2_k127_4129534_11 Protein of unknown function (DUF445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 412.0
HFD2_k127_4129534_12 Protein of unknown function (DUF763) K09003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009041 385.0
HFD2_k127_4129534_13 PFAM glycosyl hydrolase 53 domain protein K01224 - 3.2.1.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 299.0
HFD2_k127_4129534_14 Outer membrane protein beta-barrel domain - - - 0.000000000000000000000000000000000000001258 156.0
HFD2_k127_4129534_15 rhodanese-related sulfurtransferase - - - 0.0000000000000000000000000000001437 126.0
HFD2_k127_4129534_16 Carboxypeptidase regulatory-like domain K02014 - - 0.00000000000009996 84.0
HFD2_k127_4129534_17 - - - - 0.0000000000003174 72.0
HFD2_k127_4129534_2 beta-galactosidase activity K01190 - 3.2.1.23 9.29e-286 913.0
HFD2_k127_4129534_3 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 1.601e-273 868.0
HFD2_k127_4129534_4 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 1.276e-272 859.0
HFD2_k127_4129534_5 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 9.799e-255 804.0
HFD2_k127_4129534_6 SusD family K21572 - - 1.705e-208 664.0
HFD2_k127_4129534_7 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 489.0
HFD2_k127_4129534_8 galactose-1-phosphate uridylyltransferase K00965 GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0046872,GO:0046914,GO:0070569,GO:0071704,GO:1901575 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 460.0
HFD2_k127_4129534_9 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 444.0
HFD2_k127_4144809_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 364.0
HFD2_k127_4144809_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001944 272.0
HFD2_k127_4144809_2 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000001735 156.0
HFD2_k127_4150751_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 510.0
HFD2_k127_4150751_1 gluconolactonase activity K01053 GO:0003674,GO:0003824,GO:0004341,GO:0016787,GO:0016788,GO:0052689 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 461.0
HFD2_k127_4150751_10 Dehydrogenase K04109 - 1.3.7.9 0.0006972 44.0
HFD2_k127_4150751_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 355.0
HFD2_k127_4150751_3 FRG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 327.0
HFD2_k127_4150751_4 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000007579 225.0
HFD2_k127_4150751_5 - - - - 0.00000000000000000000000000000000000000000000000000006871 199.0
HFD2_k127_4150751_6 methyltransferase - - - 0.0000000000000000000000000000000005293 149.0
HFD2_k127_4150751_8 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000008732 101.0
HFD2_k127_4150751_9 PFAM HD domain K06950 - - 0.000002754 57.0
HFD2_k127_4161251_0 Nitronate monooxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 432.0
HFD2_k127_4161251_1 COGs COG0160 4-aminobutyrate aminotransferase and related aminotransferase K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004614 408.0
HFD2_k127_4161251_10 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000002884 194.0
HFD2_k127_4161251_11 Belongs to the DEAD box helicase family K05592,K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 0.00000000000000000000000000000000000000000000000008854 197.0
HFD2_k127_4161251_12 Low molecular weight phosphatase family K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000001671 166.0
HFD2_k127_4161251_13 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000000004658 157.0
HFD2_k127_4161251_14 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000007976 150.0
HFD2_k127_4161251_15 DinB superfamily - - - 0.000000000000000000000000000000000000001056 154.0
HFD2_k127_4161251_16 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000008275 154.0
HFD2_k127_4161251_17 OsmC-like protein K04063 - - 0.000000000000000000000000000000000005205 147.0
HFD2_k127_4161251_18 Transglycosylase SLT domain - - - 0.0000000000000000000000000008103 124.0
HFD2_k127_4161251_19 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000001268 106.0
HFD2_k127_4161251_2 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 391.0
HFD2_k127_4161251_21 Ethylbenzene dehydrogenase - - - 0.0000000261 66.0
HFD2_k127_4161251_22 CAAX protease self-immunity K07052 - - 0.00000195 59.0
HFD2_k127_4161251_23 - - - - 0.0000228 55.0
HFD2_k127_4161251_24 - - - - 0.0003834 51.0
HFD2_k127_4161251_3 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 384.0
HFD2_k127_4161251_4 Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 318.0
HFD2_k127_4161251_5 protein histidine kinase activity K03407,K07678 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 311.0
HFD2_k127_4161251_6 ECF sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000102 265.0
HFD2_k127_4161251_7 Fructosamine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001002 261.0
HFD2_k127_4161251_8 photoreceptor activity K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000009802 269.0
HFD2_k127_4161251_9 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000001361 218.0
HFD2_k127_4190114_0 PFAM Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 517.0
HFD2_k127_4190114_1 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000000000000000000000000000000000000000000000000000000000001693 242.0
HFD2_k127_4190114_2 Psort location Cytoplasmic, score K00945 - 2.7.4.25 0.0000000000000000000000000000000009294 139.0
HFD2_k127_4211173_0 Glycosyl hydrolases family 2 K01192 - 3.2.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 577.0
HFD2_k127_4211173_1 LytB protein K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 502.0
HFD2_k127_4211173_10 - - - - 0.000000000000000000000000000513 133.0
HFD2_k127_4211173_11 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000002641 108.0
HFD2_k127_4211173_12 Arac family - - - 0.000003401 58.0
HFD2_k127_4211173_2 PFAM peptidase M18 aminopeptidase I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 454.0
HFD2_k127_4211173_3 Histone deacetylase domain K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 413.0
HFD2_k127_4211173_4 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000001373 182.0
HFD2_k127_4211173_5 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000904 175.0
HFD2_k127_4211173_6 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000008468 176.0
HFD2_k127_4211173_7 Cbs domain K04767 - - 0.0000000000000000000000000000000000000000001315 173.0
HFD2_k127_4211173_8 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 - 3.5.1.9 0.00000000000000000000000000000000000005764 156.0
HFD2_k127_4211173_9 GAF domain-containing protein K08968 - 1.8.4.14 0.00000000000000000000000000000000318 134.0
HFD2_k127_4272472_0 Carbohydrate family 9 binding domain-like - - - 2.89e-291 920.0
HFD2_k127_4272472_1 TIGRFAM cysteine desulfurase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009131 576.0
HFD2_k127_4272472_10 Protein of unknown function (DUF1641) - - - 0.0001105 50.0
HFD2_k127_4272472_2 pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 503.0
HFD2_k127_4272472_3 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 404.0
HFD2_k127_4272472_4 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000003398 196.0
HFD2_k127_4272472_5 TonB dependent receptor K16089 - - 0.00000000000000000000000000000000006656 144.0
HFD2_k127_4272472_6 tRNA wobble cytosine modification - - - 0.0000000000000000000000000000699 132.0
HFD2_k127_4272472_7 DsrC like protein K11179 - - 0.0000000000000000000000000002006 123.0
HFD2_k127_4272472_8 - - - - 0.00000000000000000000000001321 121.0
HFD2_k127_4272472_9 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.000000000003025 79.0
HFD2_k127_4277675_0 Heavy-metal-associated domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005179 289.0
HFD2_k127_4277675_1 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000000000002294 125.0
HFD2_k127_4338475_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667 - 4.1.99.1 8.876e-214 674.0
HFD2_k127_4338475_1 PFAM Xanthine uracil vitamin C permease K06901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008685 474.0
HFD2_k127_4338475_2 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 457.0
HFD2_k127_4338475_3 O-linked N-acetylglucosamine transferase SPINDLY family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 368.0
HFD2_k127_4338475_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000005595 256.0
HFD2_k127_4338475_5 Peptidase family M28 - - - 0.00000000000000000000000000000000004626 149.0
HFD2_k127_4338475_6 peroxiredoxin activity - - - 0.000000008323 63.0
HFD2_k127_4341990_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 598.0
HFD2_k127_4341990_1 N-terminal domain of (some) glycogen debranching enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 563.0
HFD2_k127_4341990_2 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 459.0
HFD2_k127_4341990_3 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 323.0
HFD2_k127_4341990_4 HAMP domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000004914 237.0
HFD2_k127_4341990_5 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000132 228.0
HFD2_k127_4341990_6 Protein of unknown function DUF47 K02039,K07220 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.00000000000000000000000000000000000000000000000001824 190.0
HFD2_k127_4341990_7 IMP dehydrogenase activity - GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0030312,GO:0035821,GO:0036293,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0070482,GO:0071944,GO:0075136 - 0.00000000000000000000000000001263 129.0
HFD2_k127_435251_0 Seven times multi-haem cytochrome CxxCH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 509.0
HFD2_k127_435251_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 481.0
HFD2_k127_435251_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 400.0
HFD2_k127_435251_4 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000002606 185.0
HFD2_k127_435251_5 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000001205 142.0
HFD2_k127_435251_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000008978 119.0
HFD2_k127_435251_7 CYTH - - - 0.00000000003059 71.0
HFD2_k127_435251_8 Copper binding proteins, plastocyanin/azurin family - - - 0.0003153 51.0
HFD2_k127_4424877_0 Outer membrane protein beta-barrel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 389.0
HFD2_k127_4424877_1 Belongs to the serpin family K13963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008314 322.0
HFD2_k127_4424877_2 copper resistance K07245,K14166 - - 0.000000000000000000000000000000000000011 159.0
HFD2_k127_4424877_3 trehalose-phosphatase activity - - - 0.0002859 50.0
HFD2_k127_443358_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 5.154e-233 762.0
HFD2_k127_443358_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 357.0
HFD2_k127_443358_10 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000297 182.0
HFD2_k127_443358_11 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000001787 156.0
HFD2_k127_443358_12 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000372 149.0
HFD2_k127_443358_13 Aerotolerance regulator N-terminal - - - 0.00000472 60.0
HFD2_k127_443358_2 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007901 288.0
HFD2_k127_443358_3 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002009 271.0
HFD2_k127_443358_4 Part of the ABC transporter FtsEX involved in K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000003942 236.0
HFD2_k127_443358_5 Lytic transglycosylase catalytic K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000003356 235.0
HFD2_k127_443358_6 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000006453 244.0
HFD2_k127_443358_7 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000008286 236.0
HFD2_k127_443358_8 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000001401 226.0
HFD2_k127_443358_9 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000001961 228.0
HFD2_k127_4436928_0 - K13582,K13924,K15580 - 2.1.1.80,3.1.1.61 0.0 1214.0
HFD2_k127_4436928_1 ATPase involved in DNA repair - - - 0.0 1165.0
HFD2_k127_4436928_10 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 604.0
HFD2_k127_4436928_11 Oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 566.0
HFD2_k127_4436928_12 1,4-alpha-glucan branching enzyme activity K00700,K01187 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18,3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009633 552.0
HFD2_k127_4436928_13 tagaturonate epimerase K21619 - 5.1.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 526.0
HFD2_k127_4436928_14 TonB-linked outer membrane protein, SusC RagA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 559.0
HFD2_k127_4436928_15 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain K01173,K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 477.0
HFD2_k127_4436928_16 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009905 477.0
HFD2_k127_4436928_17 COGs COG2382 Enterochelin esterase K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 469.0
HFD2_k127_4436928_18 Major facilitator superfamily K02429 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 447.0
HFD2_k127_4436928_19 Alpha-L-fucosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 462.0
HFD2_k127_4436928_2 TonB-linked outer membrane protein, SusC RagA family - - - 0.0 1145.0
HFD2_k127_4436928_20 Alpha-L-fucosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 459.0
HFD2_k127_4436928_21 alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 431.0
HFD2_k127_4436928_22 PFAM glycoside hydrolase family 62 K22350 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 383.0
HFD2_k127_4436928_23 FAD binding domain K11472 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000499 370.0
HFD2_k127_4436928_24 aldo keto reductase K17744 - 1.1.1.316 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 326.0
HFD2_k127_4436928_25 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 317.0
HFD2_k127_4436928_26 LamB/YcsF family K07160 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 306.0
HFD2_k127_4436928_27 Belongs to the serpin family K13963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 299.0
HFD2_k127_4436928_28 Allophanate hydrolase subunit 2 K06350 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005961 302.0
HFD2_k127_4436928_29 chitin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004261 271.0
HFD2_k127_4436928_3 hydrolase family, 3 K05349 - 3.2.1.21 0.0 1130.0
HFD2_k127_4436928_30 Cysteine-rich domain K11473 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 - 0.000000000000000000000000000000000000000000000000000000000000000000000004182 248.0
HFD2_k127_4436928_31 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000001975 244.0
HFD2_k127_4436928_32 allophanate hydrolase subunit 1 K06351 - - 0.0000000000000000000000000000000000000000000000000000000000000000155 238.0
HFD2_k127_4436928_33 Transcriptional Regulator, AraC family - - - 0.0000000000000000000000000000000000000000000000000005754 195.0
HFD2_k127_4436928_34 Putative esterase K07214 - - 0.00000000000000000000000000000000000000000000114 171.0
HFD2_k127_4436928_35 SusD family K21572 - - 0.000000000000000000000000000000000000000009837 170.0
HFD2_k127_4436928_36 Predicted membrane protein (DUF2214) K08983 - - 0.0000000000000000000000000000000000008674 144.0
HFD2_k127_4436928_37 Protein of unknown function (DUF1579) - - - 0.000000000000000000000000000000000005765 147.0
HFD2_k127_4436928_38 - - - - 0.0000000000000000000000005397 114.0
HFD2_k127_4436928_39 - - - - 0.000000000000000000000004924 118.0
HFD2_k127_4436928_4 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 0.0 1129.0
HFD2_k127_4436928_40 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000001479 98.0
HFD2_k127_4436928_41 TonB-dependent receptor plug domain - - - 0.000000000000000008516 89.0
HFD2_k127_4436928_42 amidohydrolase K07046 - - 0.00003737 50.0
HFD2_k127_4436928_5 ribosome binding - - - 0.0 1105.0
HFD2_k127_4436928_6 Belongs to the glycosyl hydrolase 31 family K07407 - 3.2.1.22 0.0 1043.0
HFD2_k127_4436928_7 PFAM RagB SusD K21572 - - 4.998e-226 714.0
HFD2_k127_4436928_8 FAD linked oxidases, C-terminal domain K00102,K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.2.4,1.1.3.15 7.734e-224 703.0
HFD2_k127_4436928_9 - - - - 5.479e-213 682.0
HFD2_k127_443942_0 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 337.0
HFD2_k127_443942_1 alpha, beta K06889 - - 0.00000000000000000000000000000000000001595 157.0
HFD2_k127_443942_2 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000003543 102.0
HFD2_k127_4443561_0 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 308.0
HFD2_k127_4443561_1 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000204 267.0
HFD2_k127_4443561_2 von Willebrand factor, type A K07114 - - 0.0001198 54.0
HFD2_k127_4445669_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 5.641e-227 711.0
HFD2_k127_4445669_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 513.0
HFD2_k127_4452695_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 464.0
HFD2_k127_4452695_1 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000047 253.0
HFD2_k127_4452695_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.0000000000000000000000000000000000000000000000000000000005954 221.0
HFD2_k127_4452695_3 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000001069 170.0
HFD2_k127_4452695_4 - - - - 0.000000000000000000000007932 114.0
HFD2_k127_4469572_0 PFAM cytochrome bd ubiquinol oxidase subunit I K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 561.0
HFD2_k127_4469572_1 PFAM cytochrome bd ubiquinol oxidase subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 365.0
HFD2_k127_4469572_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006452 328.0
HFD2_k127_4469572_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K01299 - 3.4.17.19 0.000000000000000009107 90.0
HFD2_k127_4487355_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 7.754e-304 944.0
HFD2_k127_4487355_1 Belongs to the ALAD family K01698 GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 429.0
HFD2_k127_4487355_10 positive regulation of growth rate - - - 0.000000000000000001449 98.0
HFD2_k127_4487355_2 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 353.0
HFD2_k127_4487355_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 326.0
HFD2_k127_4487355_4 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000001961 184.0
HFD2_k127_4487355_5 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.00000000000000000000000000003117 122.0
HFD2_k127_4487355_6 Glycoprotease K14742 - - 0.00000000000000000000000000928 119.0
HFD2_k127_4487355_7 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000005397 114.0
HFD2_k127_4487355_8 Hydrolase, P-loop family K06925 - - 0.0000000000000000000009395 109.0
HFD2_k127_4487355_9 PFAM Cytochrome c assembly protein - - - 0.00000000000000000002486 101.0
HFD2_k127_4490216_0 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 464.0
HFD2_k127_4490216_1 PFAM permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 436.0
HFD2_k127_4490216_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 384.0
HFD2_k127_4490216_3 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 372.0
HFD2_k127_4490216_4 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000001617 127.0
HFD2_k127_4490216_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000009784 122.0
HFD2_k127_4490216_6 helix_turn_helix, Arsenical Resistance Operon Repressor K03892,K21903 - - 0.000000000000000000000000002173 118.0
HFD2_k127_4490216_7 TonB-dependent Receptor Plug - - - 0.00000000000000000001689 93.0
HFD2_k127_4490216_8 Thioredoxin domain - - - 0.00000000000000000008144 92.0
HFD2_k127_4490216_9 - - - - 0.000000000001724 76.0
HFD2_k127_4504457_0 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000007149 127.0
HFD2_k127_4504457_1 peptidase - - - 0.000001313 59.0
HFD2_k127_4515243_0 MacB-like periplasmic core domain K02004 - - 5.294e-245 786.0
HFD2_k127_4515243_1 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 290.0
HFD2_k127_4515243_2 Lipocalin-like domain - - - 0.0000000000000008105 93.0
HFD2_k127_4518487_0 Insulinase (Peptidase family M16) K07263 - - 3.057e-237 762.0
HFD2_k127_4518487_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000189 286.0
HFD2_k127_4518487_2 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000112 287.0
HFD2_k127_4518487_3 PFAM Glycosyl transferase, group 1 K08256 - 2.4.1.345 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002017 279.0
HFD2_k127_4518487_4 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000001047 186.0
HFD2_k127_4518487_5 DisA bacterial checkpoint controller nucleotide-binding - - - 0.00000000000000000000000000000000000000000000007173 180.0
HFD2_k127_4518487_6 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000038 169.0
HFD2_k127_4518487_7 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000003577 147.0
HFD2_k127_4518487_8 hydrolase activity, acting on ester bonds K01259 - 3.4.11.5 0.000000001218 67.0
HFD2_k127_4519103_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 9.981e-255 801.0
HFD2_k127_4519103_1 4Fe-4S dicluster domain K00184 - - 8.158e-201 667.0
HFD2_k127_4519103_10 Tetratricopeptide repeat - - - 0.000000008055 67.0
HFD2_k127_4519103_11 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000005371 64.0
HFD2_k127_4519103_12 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00003546 55.0
HFD2_k127_4519103_2 PFAM Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 614.0
HFD2_k127_4519103_3 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 529.0
HFD2_k127_4519103_4 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000000000000002129 217.0
HFD2_k127_4519103_5 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000003275 166.0
HFD2_k127_4519103_6 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000001079 148.0
HFD2_k127_4519103_7 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000000000001447 119.0
HFD2_k127_4519103_8 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000000664 101.0
HFD2_k127_4519103_9 cytochrome c - - - 0.000000000000003073 85.0
HFD2_k127_4539039_0 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 7.471e-274 849.0
HFD2_k127_4539039_1 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 434.0
HFD2_k127_4539039_10 PFAM DoxX family protein K16937 - 1.8.5.2 0.0007889 49.0
HFD2_k127_4539039_2 amino acid transport K02030,K16254 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 298.0
HFD2_k127_4539039_3 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001132 286.0
HFD2_k127_4539039_4 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000009501 267.0
HFD2_k127_4539039_5 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000569 222.0
HFD2_k127_4539039_6 amino acid transport K02030 - - 0.000000000000000000000000000000000000000000000000000000000002061 226.0
HFD2_k127_4539039_7 PFAM Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000185 208.0
HFD2_k127_4539039_8 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000005176 170.0
HFD2_k127_4539039_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000003869 112.0
HFD2_k127_4553584_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 430.0
HFD2_k127_4553584_1 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 403.0
HFD2_k127_4553584_2 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 302.0
HFD2_k127_4553584_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003306 246.0
HFD2_k127_4553584_4 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000001952 217.0
HFD2_k127_4553584_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000001148 172.0
HFD2_k127_4553584_6 Guanylyl transferase CofC like K09931 - - 0.00000000000000000000000000000000000000328 158.0
HFD2_k127_4553584_7 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.00000000000000000000000000000000000004891 150.0
HFD2_k127_4561367_0 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005855 499.0
HFD2_k127_4561367_1 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 298.0
HFD2_k127_4561367_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000002256 236.0
HFD2_k127_4561367_3 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000004792 198.0
HFD2_k127_4561367_4 FRG - - - 0.00000000000000000001131 91.0
HFD2_k127_4561367_5 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) - - - 0.0000000000000000004725 93.0
HFD2_k127_4561367_6 GCN5-related N-acetyl-transferase K06975 - - 0.000000000000000001863 88.0
HFD2_k127_4570419_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1056.0
HFD2_k127_4570419_1 - - - - 0.0000000000005101 76.0
HFD2_k127_4594078_0 Belongs to the IlvD Edd family K22396 GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019520,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0050401,GO:0071704,GO:0072329,GO:1901575 4.2.1.82 1.886e-289 905.0
HFD2_k127_4594078_1 Fumarylacetoacetate (FAA) hydrolase family K14259 - 4.2.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007625 334.0
HFD2_k127_4594078_2 Aldehyde dehydrogenase family K13877 - 1.2.1.26 0.000000000000000000000000000001453 126.0
HFD2_k127_4647074_0 Beta galactosidase small chain K01190 - 3.2.1.23 1.808e-320 1023.0
HFD2_k127_4647074_1 Belongs to the glycosyl hydrolase 2 family K01195 - 3.2.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000002279 256.0
HFD2_k127_4648358_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 1.658e-309 972.0
HFD2_k127_4648358_1 lactoylglutathione lyase activity - - - 0.0000000000000000001564 95.0
HFD2_k127_466491_0 Large extracellular alpha-helical protein K09607 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 569.0
HFD2_k127_466491_1 - - - - 0.000000000008636 77.0
HFD2_k127_4691683_0 LVIVD repeat - - - 3.069e-272 859.0
HFD2_k127_4691683_1 Domain of unknown function (DUF305) - - - 0.00000000000000000000000000000149 123.0
HFD2_k127_4724679_0 - - - - 8.869e-213 688.0
HFD2_k127_4724679_1 UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 542.0
HFD2_k127_4724679_10 Cold shock K03704 - - 0.00000000000000000000000000000002245 127.0
HFD2_k127_4724679_11 protein-glutamate O-methyltransferase activity K00575 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896 2.1.1.80 0.00000000000000000000000000005071 119.0
HFD2_k127_4724679_12 ThiS family K03636 - - 0.00000000000000000000002077 107.0
HFD2_k127_4724679_13 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.0000000000000001753 91.0
HFD2_k127_4724679_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 497.0
HFD2_k127_4724679_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 442.0
HFD2_k127_4724679_4 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005002 431.0
HFD2_k127_4724679_5 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 390.0
HFD2_k127_4724679_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000003755 222.0
HFD2_k127_4724679_7 CheC inhibitor of MCP methylation K03410 - - 0.00000000000000000000000000000000000000000005087 172.0
HFD2_k127_4724679_8 Cytochrome c - - - 0.000000000000000000000000000000005637 132.0
HFD2_k127_4724679_9 phosphorelay signal transduction system K03413 - - 0.000000000000000000000000000000007205 145.0
HFD2_k127_4729865_0 Ketoacyl-synthetase C-terminal extension - - - 3.843e-285 907.0
HFD2_k127_4729865_1 Peptidase S46 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 541.0
HFD2_k127_4729865_10 COGs COG1853 Conserved protein domain typically associated with flavoprotein oxygenase DIM6 NTAB family K00484 - 1.5.1.36 0.0000000000000000000008817 109.0
HFD2_k127_4729865_11 PFAM glycoside hydrolase, family 13 domain protein - - - 0.000000000000000000009287 100.0
HFD2_k127_4729865_12 cheY-homologous receiver domain - - - 0.00000000000000003545 91.0
HFD2_k127_4729865_2 Carboxypeptidase regulatory-like domain K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000629 489.0
HFD2_k127_4729865_3 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006032 375.0
HFD2_k127_4729865_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 362.0
HFD2_k127_4729865_5 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000003079 252.0
HFD2_k127_4729865_6 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000004749 204.0
HFD2_k127_4729865_7 Domain of unknown function (DUF4974) K07165 - - 0.0000000000000000000000000000000000000000002176 171.0
HFD2_k127_4729865_8 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.0000000000000000000000000000000003629 145.0
HFD2_k127_4729865_9 ECF sigma factor K03088 - - 0.000000000000000000000000000000002095 136.0
HFD2_k127_4735959_0 transmembrane transporter activity K08191 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 537.0
HFD2_k127_4735959_1 ROK family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 507.0
HFD2_k127_4735959_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 400.0
HFD2_k127_4735959_3 unsaturated chondroitin disaccharide hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 347.0
HFD2_k127_4752778_0 Glycosyltransferase 36 associated - - - 0.0 1035.0
HFD2_k127_4752778_1 Amidase K02433 - 6.3.5.6,6.3.5.7 3.822e-303 938.0
HFD2_k127_4752778_10 cellulase activity - - - 0.000000000000006002 89.0
HFD2_k127_4752778_11 protein kinase activity - - - 0.0004617 54.0
HFD2_k127_4752778_2 COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 584.0
HFD2_k127_4752778_3 N,N-dimethylaniline monooxygenase activity K07222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 502.0
HFD2_k127_4752778_4 Belongs to the ABC transporter superfamily K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 419.0
HFD2_k127_4752778_5 virion core protein, lumpy skin disease virus - - - 0.000000000000000000000000000000000000000000000000000001215 200.0
HFD2_k127_4752778_6 phosphorelay signal transduction system K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000003388 215.0
HFD2_k127_4752778_7 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000001097 180.0
HFD2_k127_4752778_8 Phosphodiester glycosidase - - - 0.000000000000000000000000000000000000000000000005182 188.0
HFD2_k127_4754338_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 451.0
HFD2_k127_4754338_1 spore germination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 420.0
HFD2_k127_4754338_2 Nitroreductase family - - - 0.00000000000000000000000000000000000007087 151.0
HFD2_k127_475706_0 Belongs to the malate synthase family K01638 - 2.3.3.9 8.289e-221 701.0
HFD2_k127_4757363_0 Domain of unknown function (DUF4445) - - - 4.081e-242 761.0
HFD2_k127_4757363_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 7.596e-195 614.0
HFD2_k127_4757363_10 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004222 258.0
HFD2_k127_4757363_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000945 241.0
HFD2_k127_4757363_12 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000004009 209.0
HFD2_k127_4757363_13 - - - - 0.000000000000000000000000000001862 136.0
HFD2_k127_4757363_14 Protein of unknown function (DUF1634) - - - 0.000000004963 68.0
HFD2_k127_4757363_2 Catalyzes the interconversion of ornithine to glutamate semialdehyde K00819 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 538.0
HFD2_k127_4757363_3 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005986 527.0
HFD2_k127_4757363_4 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 454.0
HFD2_k127_4757363_5 methionine synthase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 451.0
HFD2_k127_4757363_6 cobalamin binding K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 380.0
HFD2_k127_4757363_7 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 349.0
HFD2_k127_4757363_8 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 361.0
HFD2_k127_4757363_9 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002787 258.0
HFD2_k127_4773734_0 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 406.0
HFD2_k127_4773734_1 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000171 265.0
HFD2_k127_4773734_2 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000002315 194.0
HFD2_k127_4773734_3 HAMP domain K02482 - 2.7.13.3 0.0000000000000000000000000000000000007672 156.0
HFD2_k127_4773734_4 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000238 91.0
HFD2_k127_4785344_0 Sodium:solute symporter family - - - 2.363e-271 846.0
HFD2_k127_4785344_1 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 310.0
HFD2_k127_4785344_2 alginic acid biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001618 261.0
HFD2_k127_4785344_3 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000002636 207.0
HFD2_k127_4790271_0 UDP binding domain K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 563.0
HFD2_k127_4790271_1 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000804 519.0
HFD2_k127_4790271_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 430.0
HFD2_k127_4790271_3 Capsular polysaccharide biosynthesis protein K01104 - 3.1.3.48 0.0000000000000000001007 97.0
HFD2_k127_4790271_4 translation initiation factor activity - - - 0.0000000009837 72.0
HFD2_k127_4793012_0 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000000000004003 181.0
HFD2_k127_4793012_1 methylamine metabolic process K15977 - - 0.0000000000000000000000000000000000000000000003501 171.0
HFD2_k127_4793012_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000004553 55.0
HFD2_k127_4798011_0 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0 1097.0
HFD2_k127_4798011_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 4.915e-302 944.0
HFD2_k127_4798011_10 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000001793 155.0
HFD2_k127_4798011_11 peptidoglycan binding K03642,K19560 - 3.1.1.85 0.0000000000000000000000000000009656 141.0
HFD2_k127_4798011_12 Bacterial transcription activator, effector binding domain K13652 - - 0.000000000000000000002784 100.0
HFD2_k127_4798011_13 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000009811 90.0
HFD2_k127_4798011_14 Bacterial transcription activator, effector binding domain K13652 - - 0.000000000000002859 85.0
HFD2_k127_4798011_2 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 2.572e-215 711.0
HFD2_k127_4798011_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 549.0
HFD2_k127_4798011_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 523.0
HFD2_k127_4798011_5 PFAM transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 403.0
HFD2_k127_4798011_6 adenosine deaminase K01488 - 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 401.0
HFD2_k127_4798011_7 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 365.0
HFD2_k127_4798011_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 311.0
HFD2_k127_4798011_9 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000006341 266.0
HFD2_k127_4812328_0 hydrolase activity, hydrolyzing O-glycosyl compounds K01176,K01200 - 3.2.1.1,3.2.1.41 4.315e-198 644.0
HFD2_k127_4812328_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 480.0
HFD2_k127_4817952_0 Nickel-dependent hydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 579.0
HFD2_k127_4817952_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 429.0
HFD2_k127_4817952_10 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L - - - 0.0000000000000000000000000000000000000000000537 168.0
HFD2_k127_4817952_11 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K12143,K15831 - - 0.00000000000000000000000000000000000002079 151.0
HFD2_k127_4817952_12 spore germination K00442,K03605,K08315 - 3.4.23.51 0.000000000000001215 86.0
HFD2_k127_4817952_13 spore germination K03605 - - 0.0001203 55.0
HFD2_k127_4817952_2 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K12139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 421.0
HFD2_k127_4817952_3 Proton-conducting membrane transporter K12141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 373.0
HFD2_k127_4817952_4 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006119 297.0
HFD2_k127_4817952_5 histidine kinase, HAMP K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001404 265.0
HFD2_k127_4817952_6 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003407 242.0
HFD2_k127_4817952_7 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000008788 224.0
HFD2_k127_4817952_8 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299 - 1.17.1.10,1.17.1.9 0.0000000000000000000000000000000000000000000000000000002854 216.0
HFD2_k127_4817952_9 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000005705 188.0
HFD2_k127_4827213_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 1.435e-282 885.0
HFD2_k127_4827213_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007855 572.0
HFD2_k127_4827213_10 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000007702 166.0
HFD2_k127_4827213_11 transport - - - 0.00000000000000000000000000006886 130.0
HFD2_k127_4827213_12 PFAM phosphoesterase, RecJ domain protein - - - 0.0000000000000000000000000001763 131.0
HFD2_k127_4827213_13 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.000000000000000000000000001447 118.0
HFD2_k127_4827213_14 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000133 100.0
HFD2_k127_4827213_15 Domain of unknown function (DUF2383) - - - 0.00000000000000000001148 104.0
HFD2_k127_4827213_16 Methyltransferase domain - - - 0.00000000000000000006477 98.0
HFD2_k127_4827213_17 - - - - 0.00000000000000005802 83.0
HFD2_k127_4827213_19 metal-dependent phosphoesterases (PHP family) - - - 0.0003189 51.0
HFD2_k127_4827213_2 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 302.0
HFD2_k127_4827213_3 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005897 289.0
HFD2_k127_4827213_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000394 198.0
HFD2_k127_4827213_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000005331 194.0
HFD2_k127_4827213_6 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000002144 194.0
HFD2_k127_4827213_7 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000001797 180.0
HFD2_k127_4827213_8 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000002961 166.0
HFD2_k127_4827213_9 - - - - 0.0000000000000000000000000000000000000000003917 171.0
HFD2_k127_4847596_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 553.0
HFD2_k127_4847596_1 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 501.0
HFD2_k127_4847596_2 Beta-eliminating lyase K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 479.0
HFD2_k127_4847596_3 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 389.0
HFD2_k127_4847596_4 Nitrogen fixation protein NifU K04488 - - 0.000000000000000000000000000000000002473 153.0
HFD2_k127_4847596_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000003033 142.0
HFD2_k127_4847596_6 Benzene 1,2-dioxygenase K05710 - - 0.000000000000000000000000662 108.0
HFD2_k127_4862305_0 PFAM tRNA synthetases class I (E and Q), catalytic domain K01886 - 6.1.1.18 6.036e-265 837.0
HFD2_k127_4862305_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.17 3.442e-206 652.0
HFD2_k127_4862305_10 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000001285 66.0
HFD2_k127_4862305_2 Belongs to the aldehyde dehydrogenase family K00135,K22445 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.99.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 593.0
HFD2_k127_4862305_3 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 589.0
HFD2_k127_4862305_4 polysaccharide deacetylase K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 577.0
HFD2_k127_4862305_5 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009842 331.0
HFD2_k127_4862305_6 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000005024 271.0
HFD2_k127_4862305_7 CDP-alcohol phosphatidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004014 244.0
HFD2_k127_4862305_8 DinB family - - - 0.0000000000000000000000962 109.0
HFD2_k127_4862305_9 Protein of unknown function (DUF2892) - - - 0.0000000000000002353 89.0
HFD2_k127_4862798_0 beta-galactosidase activity - - - 0.0 1250.0
HFD2_k127_4862798_1 hydrolase, family 3 K05349 - 3.2.1.21 8.418e-305 957.0
HFD2_k127_4862798_2 Belongs to the glycosyl hydrolase 30 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 548.0
HFD2_k127_4862798_3 glucosamine-6-phosphate deaminase activity K01057,K02564 - 3.1.1.31,3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 336.0
HFD2_k127_4862798_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000008872 187.0
HFD2_k127_4862798_5 - - - - 0.000000000000000000000000000000000000122 148.0
HFD2_k127_4868950_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 1.98e-213 689.0
HFD2_k127_4880890_0 ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 330.0
HFD2_k127_4880890_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000001384 228.0
HFD2_k127_4880890_2 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000002466 181.0
HFD2_k127_4898203_0 coagulation factor 5 8 type - - - 1.15e-245 804.0
HFD2_k127_4898203_1 TonB-dependent receptor - - - 4.841e-196 646.0
HFD2_k127_4898203_10 Thioredoxin - - - 0.00000000000000002013 92.0
HFD2_k127_4898203_2 Putative glucoamylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 589.0
HFD2_k127_4898203_3 ABC transporter substrate-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005773 430.0
HFD2_k127_4898203_4 transmembrane transport K02025,K15771 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 383.0
HFD2_k127_4898203_5 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006684 328.0
HFD2_k127_4898203_6 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 317.0
HFD2_k127_4898203_7 Transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 316.0
HFD2_k127_4898203_8 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000002932 239.0
HFD2_k127_4898203_9 GYD domain - - - 0.000000000000000000000003146 112.0
HFD2_k127_4900610_0 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 606.0
HFD2_k127_4900610_1 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 356.0
HFD2_k127_4900610_2 RDD family K06384 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 352.0
HFD2_k127_4900610_3 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007055 266.0
HFD2_k127_4900610_5 ankyrin repeats - - - 0.0000000000002265 84.0
HFD2_k127_4900610_6 pathogenesis K02417,K02519 - - 0.0000000000003215 80.0
HFD2_k127_4900610_7 Domain of unknown function (DUF4129) - - - 0.00001066 55.0
HFD2_k127_4900610_8 3-demethylubiquinone-9 3-O-methyltransferase activity K03428 - 2.1.1.11 0.0004845 45.0
HFD2_k127_4934679_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 8.288e-242 773.0
HFD2_k127_4934679_1 Peptidase family M1 domain - - - 3.023e-236 775.0
HFD2_k127_4934679_10 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006742 302.0
HFD2_k127_4934679_11 Pfam:DUF1498 K09988 - 5.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004678 279.0
HFD2_k127_4934679_12 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000008679 267.0
HFD2_k127_4934679_13 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000027 227.0
HFD2_k127_4934679_14 Protein of unknown function DUF99 K09120 - - 0.00000000000000000000000000000000000000000000000000000000000000009778 227.0
HFD2_k127_4934679_15 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000003625 229.0
HFD2_k127_4934679_16 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000001471 220.0
HFD2_k127_4934679_17 NUDIX hydrolase K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000001663 228.0
HFD2_k127_4934679_18 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000000000000000000000113 177.0
HFD2_k127_4934679_19 Protein of unknown function (DUF1572) - - - 0.0000000000000000000000000000000000000000000225 168.0
HFD2_k127_4934679_2 lysine biosynthetic process via aminoadipic acid - - - 1.036e-216 700.0
HFD2_k127_4934679_20 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.0000000000000000000000000000000000000004194 162.0
HFD2_k127_4934679_21 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000008701 144.0
HFD2_k127_4934679_22 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000562 130.0
HFD2_k127_4934679_24 PFAM Abortive infection protein K07052 - - 0.0000000000000000001556 104.0
HFD2_k127_4934679_25 Regulator of chromosome condensation (RCC1) repeat - - - 0.000000000003177 80.0
HFD2_k127_4934679_26 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000003752 66.0
HFD2_k127_4934679_28 SprT homologues. - - - 0.000003499 59.0
HFD2_k127_4934679_3 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005856 548.0
HFD2_k127_4934679_4 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 478.0
HFD2_k127_4934679_5 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 394.0
HFD2_k127_4934679_6 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000522 340.0
HFD2_k127_4934679_7 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 336.0
HFD2_k127_4934679_8 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 310.0
HFD2_k127_4934679_9 Putative zinc-binding metallo-peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 316.0
HFD2_k127_4958731_0 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.0 1172.0
HFD2_k127_4958731_1 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 389.0
HFD2_k127_4958731_2 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007487 311.0
HFD2_k127_4958731_3 NmrA-like family K19267 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 301.0
HFD2_k127_4958731_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.0000000000000000000000000000000000000000000000000003471 189.0
HFD2_k127_4958731_5 Bacterial Ig-like domain 2 - - - 0.00000000328 64.0
HFD2_k127_499853_0 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 550.0
HFD2_k127_499853_1 COGs COG4299 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009718 391.0
HFD2_k127_499853_2 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000004712 244.0
HFD2_k127_499853_3 Belongs to the carbohydrate kinase PfkB family K00882 - 2.7.1.56 0.0000000000000000000000000000000000004264 156.0
HFD2_k127_499853_4 acr, cog1993 K09137 - - 0.00000000000000000000000000000000001299 147.0
HFD2_k127_499853_5 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000000001021 121.0
HFD2_k127_5010401_0 Pyridine nucleotide-disulphide oxidoreductase K21567 GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 355.0
HFD2_k127_5010401_1 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000002169 183.0
HFD2_k127_5010401_2 Iron permease FTR1 family K07243 - - 0.000000000000000000000000000000000000000002873 177.0
HFD2_k127_5020744_0 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000006718 115.0
HFD2_k127_5020744_1 Putative glycosyl hydrolase domain - - - 0.000000000000009268 87.0
HFD2_k127_5045503_0 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 476.0
HFD2_k127_5045503_1 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 448.0
HFD2_k127_5045503_2 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 367.0
HFD2_k127_5045503_3 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007498 334.0
HFD2_k127_5045503_4 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 329.0
HFD2_k127_5045503_5 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000003592 254.0
HFD2_k127_5045503_6 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000001306 241.0
HFD2_k127_5045503_7 - - - - 0.00006463 54.0
HFD2_k127_5045503_8 - - - - 0.0003606 51.0
HFD2_k127_5091374_0 WD40-like Beta Propeller Repeat - - - 8.153e-302 960.0
HFD2_k127_5091374_1 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 2.29e-206 666.0
HFD2_k127_5091374_10 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 379.0
HFD2_k127_5091374_11 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006398 286.0
HFD2_k127_5091374_12 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005327 278.0
HFD2_k127_5091374_13 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002657 282.0
HFD2_k127_5091374_14 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004439 270.0
HFD2_k127_5091374_15 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005638 261.0
HFD2_k127_5091374_16 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003787 258.0
HFD2_k127_5091374_17 histidine kinase, HAMP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008879 255.0
HFD2_k127_5091374_18 TIGRFAM membrane complex biogenesis protein, BtpA family K06971 - - 0.000000000000000000000000000000000000000000000000000000000000003893 247.0
HFD2_k127_5091374_19 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000003884 228.0
HFD2_k127_5091374_2 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 7.316e-204 660.0
HFD2_k127_5091374_20 lipase activity K15349 - - 0.00000000000000000000000000000000000000000000005661 186.0
HFD2_k127_5091374_21 phosphatidate phosphatase activity K00901,K01096,K19302 - 2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.0000000000000000000000000000000000000000000004367 179.0
HFD2_k127_5091374_22 Methyltransferase domain - - - 0.0000000000000000000000000000000000005772 151.0
HFD2_k127_5091374_23 Transmembrane and TPR repeat-containing protein - GO:0001763,GO:0002009,GO:0003401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0006950,GO:0007275,GO:0008150,GO:0009653,GO:0009791,GO:0009887,GO:0009888,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010468,GO:0010604,GO:0012505,GO:0019222,GO:0030154,GO:0030162,GO:0030323,GO:0030324,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0033554,GO:0034976,GO:0035239,GO:0035295,GO:0040007,GO:0042176,GO:0042692,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045732,GO:0045862,GO:0048286,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048729,GO:0048731,GO:0048747,GO:0048754,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051146,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051716,GO:0055001,GO:0055002,GO:0060255,GO:0060425,GO:0060429,GO:0060441,GO:0060447,GO:0060541,GO:0060560,GO:0060562,GO:0060602,GO:0061061,GO:0061136,GO:0061138,GO:0065007,GO:0080090,GO:1901800,GO:1903050,GO:1903052,GO:1903362,GO:1903364 - 0.00000000000000000000000000000004991 146.0
HFD2_k127_5091374_24 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000001042 137.0
HFD2_k127_5091374_25 positive regulation of proteasomal protein catabolic process - GO:0001763,GO:0002009,GO:0003401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0006950,GO:0007275,GO:0008150,GO:0009653,GO:0009791,GO:0009887,GO:0009888,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010468,GO:0010604,GO:0012505,GO:0019222,GO:0030154,GO:0030162,GO:0030323,GO:0030324,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0033554,GO:0034976,GO:0035239,GO:0035295,GO:0040007,GO:0042176,GO:0042692,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045732,GO:0045862,GO:0048286,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048729,GO:0048731,GO:0048747,GO:0048754,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051146,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051716,GO:0055001,GO:0055002,GO:0060255,GO:0060425,GO:0060429,GO:0060441,GO:0060447,GO:0060541,GO:0060560,GO:0060562,GO:0060602,GO:0061061,GO:0061136,GO:0061138,GO:0065007,GO:0080090,GO:1901800,GO:1903050,GO:1903052,GO:1903362,GO:1903364 - 0.0000000000000000000000000005188 131.0
HFD2_k127_5091374_26 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000001335 111.0
HFD2_k127_5091374_27 diguanylate cyclase - - - 0.000000000000000000000001192 117.0
HFD2_k127_5091374_28 - - - - 0.0000000000000000000000176 117.0
HFD2_k127_5091374_29 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000003931 101.0
HFD2_k127_5091374_3 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 597.0
HFD2_k127_5091374_30 PFAM Methyltransferase type 11 - - - 0.000000000003404 76.0
HFD2_k127_5091374_31 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000007322 66.0
HFD2_k127_5091374_4 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 611.0
HFD2_k127_5091374_5 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 523.0
HFD2_k127_5091374_6 Mur ligase middle domain K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009831 462.0
HFD2_k127_5091374_7 response regulator K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 447.0
HFD2_k127_5091374_8 PFAM Glycosyl transferase family 2 K10012 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 386.0
HFD2_k127_5091374_9 PAS domain K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 388.0
HFD2_k127_5096277_0 Polysaccharide biosynthesis protein K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 517.0
HFD2_k127_5096277_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 295.0
HFD2_k127_5096277_2 Belongs to the pseudouridine synthase RsuA family K06178,K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000006379 229.0
HFD2_k127_5096277_3 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000002228 228.0
HFD2_k127_5096277_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000004302 174.0
HFD2_k127_5096277_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000008797 162.0
HFD2_k127_5096277_6 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000005179 67.0
HFD2_k127_5108109_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 537.0
HFD2_k127_5108109_1 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 536.0
HFD2_k127_5108109_10 PFAM regulatory protein, ArsR K03892 - - 0.000001201 61.0
HFD2_k127_5108109_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 500.0
HFD2_k127_5108109_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 406.0
HFD2_k127_5108109_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000003167 245.0
HFD2_k127_5108109_5 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.000000000000000000000000000000000000000000000000000000000000003834 225.0
HFD2_k127_5108109_6 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000002178 147.0
HFD2_k127_5108109_7 - - - - 0.00000000000000000000008493 109.0
HFD2_k127_5108109_8 Histidine kinase A domain protein - - - 0.000000000000000002917 98.0
HFD2_k127_5108109_9 PRC-barrel domain - - - 0.000000000007034 76.0
HFD2_k127_5108883_0 Alpha-glucan phosphorylase K00688 - 2.4.1.1 1.056e-234 746.0
HFD2_k127_5108883_1 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 619.0
HFD2_k127_5108883_10 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002548 280.0
HFD2_k127_5108883_11 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001719 257.0
HFD2_k127_5108883_12 Bacterial transcriptional activator domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000002895 219.0
HFD2_k127_5108883_13 Belongs to the globin family K05916 - 1.14.12.17 0.0000000000000000000000000000000000000000004783 162.0
HFD2_k127_5108883_14 Globin - - - 0.00000000000000000000000000000000001623 139.0
HFD2_k127_5108883_15 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000006251 115.0
HFD2_k127_5108883_16 Protein of unknown function (DUF1569) - - - 0.0000000000000000001314 103.0
HFD2_k127_5108883_17 Bacterial regulatory proteins, tetR family - - - 0.000000000000868 80.0
HFD2_k127_5108883_18 PFAM Outer membrane efflux protein K03287 - - 0.0000001071 65.0
HFD2_k127_5108883_19 12 heme-binding sites - - - 0.0000005868 63.0
HFD2_k127_5108883_2 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 494.0
HFD2_k127_5108883_20 - - - - 0.00002095 57.0
HFD2_k127_5108883_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 426.0
HFD2_k127_5108883_4 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 408.0
HFD2_k127_5108883_5 amidase activity K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 391.0
HFD2_k127_5108883_6 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 419.0
HFD2_k127_5108883_7 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 387.0
HFD2_k127_5108883_8 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 376.0
HFD2_k127_5108883_9 Secretion protein K01993 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 318.0
HFD2_k127_514428_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1098.0
HFD2_k127_514428_1 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001094 291.0
HFD2_k127_514428_2 COG0500 SAM-dependent methyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000004311 217.0
HFD2_k127_514428_3 Histidine kinase - - - 0.0000000001334 76.0
HFD2_k127_5153228_0 Glycosyl Hydrolase Family 88 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 363.0
HFD2_k127_5153228_1 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000004734 220.0
HFD2_k127_5165507_0 Belongs to the heme-copper respiratory oxidase family K00404,K15862 - 1.9.3.1 5.256e-209 662.0
HFD2_k127_5165507_1 COG2217 Cation transport ATPase K01533 - 3.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 412.0
HFD2_k127_5165507_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 302.0
HFD2_k127_5165507_3 Belongs to the heme-copper respiratory oxidase family K15862 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000002991 248.0
HFD2_k127_5165507_4 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000001372 245.0
HFD2_k127_5165507_5 N-terminal domain of cytochrome oxidase-cbb3, FixP K00406 - - 0.00000000000000000000000000001241 128.0
HFD2_k127_5165507_6 biogenesis protein K09792 - - 0.000000000000000005763 95.0
HFD2_k127_5165507_7 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.000002449 57.0
HFD2_k127_5174115_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 5.754e-309 968.0
HFD2_k127_5174115_1 - - - - 0.00000000000000000000000000000000006576 141.0
HFD2_k127_5187690_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.038e-259 810.0
HFD2_k127_5187690_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.011e-213 693.0
HFD2_k127_5187690_2 Tannase and feruloyl esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 482.0
HFD2_k127_5187690_3 Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000001549 222.0
HFD2_k127_5187690_4 GyrI-like small molecule binding domain - - - 0.0000000000000000000000000000000000000000000000001791 183.0
HFD2_k127_5187690_5 KAP family P-loop domain - - - 0.0000000000000000000000000000000000000004765 172.0
HFD2_k127_5187690_6 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000001787 83.0
HFD2_k127_5187690_7 heat shock protein binding - - - 0.0000008885 59.0
HFD2_k127_5187690_8 Belongs to the ompA family - - - 0.0006972 44.0
HFD2_k127_5200171_0 PFAM Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 3.5e-323 994.0
HFD2_k127_5200171_1 pfkB family carbohydrate kinase K00874 - 2.7.1.45 1.485e-194 610.0
HFD2_k127_5200171_10 cobalamin binding protein K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000002491 248.0
HFD2_k127_5200171_11 PFAM Pterin binding enzyme K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000001059 250.0
HFD2_k127_5200171_12 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000004605 211.0
HFD2_k127_5200171_13 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000000000004195 202.0
HFD2_k127_5200171_14 HEAT repeats - - - 0.0000000000000000000000000000000000000000000003399 182.0
HFD2_k127_5200171_15 PFAM Cyclic nucleotide-binding domain - - - 0.000000000000004264 82.0
HFD2_k127_5200171_16 - - - - 0.0000000000002617 80.0
HFD2_k127_5200171_17 AhpC Tsa family - - - 0.000000001146 66.0
HFD2_k127_5200171_18 Tetratricopeptide repeat - - - 0.00005581 57.0
HFD2_k127_5200171_2 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 610.0
HFD2_k127_5200171_3 Glycosyl transferase family 21 K00786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 545.0
HFD2_k127_5200171_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 541.0
HFD2_k127_5200171_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 498.0
HFD2_k127_5200171_6 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 417.0
HFD2_k127_5200171_7 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 350.0
HFD2_k127_5200171_8 Sodium/calcium exchanger protein K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 326.0
HFD2_k127_5200171_9 Methylene-tetrahydrofolate reductase C terminal K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 307.0
HFD2_k127_520728_0 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 2.671e-309 968.0
HFD2_k127_520728_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.272e-202 651.0
HFD2_k127_520728_10 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009833 332.0
HFD2_k127_520728_11 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 328.0
HFD2_k127_520728_12 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 329.0
HFD2_k127_520728_13 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 314.0
HFD2_k127_520728_14 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 297.0
HFD2_k127_520728_15 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K06898,K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000004648 274.0
HFD2_k127_520728_16 Bacillithiol biosynthesis BshC K22136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008977 270.0
HFD2_k127_520728_17 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001767 254.0
HFD2_k127_520728_18 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000001123 226.0
HFD2_k127_520728_19 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000006245 175.0
HFD2_k127_520728_2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 3.326e-200 636.0
HFD2_k127_520728_20 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000000003279 163.0
HFD2_k127_520728_21 UvrB/uvrC motif K19411 - - 0.00000000000000000000000000000000000008463 157.0
HFD2_k127_520728_22 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000008137 142.0
HFD2_k127_520728_23 Outer membrane protein (OmpH-like) K06142 - - 0.00000000000000000000000000001201 125.0
HFD2_k127_520728_3 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 609.0
HFD2_k127_520728_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 462.0
HFD2_k127_520728_5 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 436.0
HFD2_k127_520728_6 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 430.0
HFD2_k127_520728_7 ATP:guanido phosphotransferase, C-terminal catalytic domain K19405 - 2.7.14.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 416.0
HFD2_k127_520728_8 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 351.0
HFD2_k127_520728_9 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 333.0
HFD2_k127_5207597_0 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 602.0
HFD2_k127_5207597_1 Aminotransferase class I and II K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 474.0
HFD2_k127_5207597_2 Deoxynucleoside kinase K15519 - 2.7.1.74,2.7.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000008895 263.0
HFD2_k127_5207597_3 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000002409 159.0
HFD2_k127_5207597_4 - - - - 0.000000000000000000000000000000000000673 148.0
HFD2_k127_5207597_5 transcriptional regulator - - - 0.00000000000000000000000000000001183 134.0
HFD2_k127_5207597_6 Protein of unknown function (DUF971) K03593 - - 0.000000000000000000000000002263 114.0
HFD2_k127_5207597_7 Predicted membrane protein (DUF2231) - - - 0.000000000000000000002833 102.0
HFD2_k127_5207597_9 Putative serine dehydratase domain - - - 0.000000001039 59.0
HFD2_k127_5214270_0 glutamine synthetase K01915 GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 2.55e-215 680.0
HFD2_k127_5214270_1 Psort location CytoplasmicMembrane, score 10.00 K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 609.0
HFD2_k127_5214270_2 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004212 279.0
HFD2_k127_5214270_3 Nitrogen regulatory protein P-II K04751 - - 0.00000000000000000000000000000000000000000000000003903 184.0
HFD2_k127_5214270_4 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000008502 165.0
HFD2_k127_5214270_5 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.00000000000000000000000005533 121.0
HFD2_k127_5214270_6 molybdopterin cofactor binding K07402 - - 0.0000000000000000001077 93.0
HFD2_k127_5214270_7 SMART Metal-dependent phosphohydrolase, HD region K07141 - 2.7.7.76 0.0000000000000000006882 101.0
HFD2_k127_5218475_0 COG0542 ATPases with chaperone activity, ATP-binding subunit K11907 - - 5.825e-307 975.0
HFD2_k127_5218475_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 4.101e-263 833.0
HFD2_k127_5218475_10 ImpE protein K11898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001169 273.0
HFD2_k127_5218475_11 PFAM Uncharacterised conserved protein UCP028301 K11901 - - 0.0000000000000000000000000000000000000000000000000000000000001215 217.0
HFD2_k127_5218475_12 Type VI secretion system effector, Hcp K11903 - - 0.000000000000000000000000000000000000000000000000000006061 194.0
HFD2_k127_5218475_13 histone H2A K63-linked ubiquitination K11894 - - 0.00000000000000000000000000000000000000000000000009831 187.0
HFD2_k127_5218475_14 PAAR motif - - - 0.000000000000000000000000000000000000000000000582 167.0
HFD2_k127_5218475_15 TIGRFAM Type VI secretion system, lysozyme-related K11897 - - 0.000000000000000000000000000000007193 133.0
HFD2_k127_5218475_16 - - - - 0.000006379 58.0
HFD2_k127_5218475_17 transposase IS116 IS110 IS902 family - - - 0.00001222 57.0
HFD2_k127_5218475_18 Peptidoglycan-binding domain 1 protein - - - 0.0005507 48.0
HFD2_k127_5218475_2 Type VI secretion protein, EvpB/VC_A0108, tail sheath K11900 - - 4.446e-235 735.0
HFD2_k127_5218475_3 Type VI secretion system, TssF K11896 - - 3.414e-210 671.0
HFD2_k127_5218475_4 ImpA, N-terminal, type VI secretion system K11902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 528.0
HFD2_k127_5218475_5 TIGRFAM type VI secretion system Vgr family protein K11904 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 531.0
HFD2_k127_5218475_6 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 510.0
HFD2_k127_5218475_7 Type VI secretion, TssG K11895 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 327.0
HFD2_k127_5218475_8 protein-(glutamine-N5) methyltransferase activity K00612 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002122 298.0
HFD2_k127_5218475_9 polysaccharide catabolic process K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007171 282.0
HFD2_k127_5223757_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 511.0
HFD2_k127_5223757_1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 500.0
HFD2_k127_5223757_2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 387.0
HFD2_k127_5223757_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000419 303.0
HFD2_k127_5223757_4 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000003357 135.0
HFD2_k127_5223757_5 BioY family K03523 - - 0.000000000000000000000000002285 125.0
HFD2_k127_5223757_6 - - - - 0.0000002891 61.0
HFD2_k127_5224396_0 Glycosyl hydrolase family 9 - - - 0.0 1080.0
HFD2_k127_5224396_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 1.087e-275 861.0
HFD2_k127_5224396_10 Cellulase (glycosyl hydrolase family 5) K19355 - 3.2.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 448.0
HFD2_k127_5224396_11 Belongs to the glycosyl hydrolase 26 family K01218 - 3.2.1.78 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009346 432.0
HFD2_k127_5224396_12 Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man) K16213 - 5.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 425.0
HFD2_k127_5224396_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 389.0
HFD2_k127_5224396_14 ribonuclease inhibitor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 336.0
HFD2_k127_5224396_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 316.0
HFD2_k127_5224396_16 Sigma-70, region 4 K02405 - - 0.00000000000000000000000000000000000000000000000000000000000000000001051 250.0
HFD2_k127_5224396_17 translation release factor activity K03265 - - 0.0000000000000000000000000000000004056 149.0
HFD2_k127_5224396_18 TonB-dependent Receptor Plug - - - 0.00000000000000000000000534 109.0
HFD2_k127_5224396_2 beta-galactosidase activity K05970 - 3.1.1.53 4.69e-221 705.0
HFD2_k127_5224396_3 alpha-galactosidase K07407 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004557,GO:0005975,GO:0005976,GO:0006080,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044238,GO:0051069,GO:0051682,GO:0071704,GO:1901575 3.2.1.22 7.163e-196 619.0
HFD2_k127_5224396_4 Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose K16212 - 2.4.1.281 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 606.0
HFD2_k127_5224396_5 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008505 594.0
HFD2_k127_5224396_6 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 560.0
HFD2_k127_5224396_7 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) K16213 - 5.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 499.0
HFD2_k127_5224396_8 Aldo/keto reductase family K19265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 463.0
HFD2_k127_5224396_9 Belongs to the glycosyl hydrolase 26 family K01218 - 3.2.1.78 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009232 449.0
HFD2_k127_5241373_0 Alpha-amylase domain K01187,K05343 - 3.2.1.1,3.2.1.20,5.4.99.16 1.121e-247 773.0
HFD2_k127_5241373_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 1.554e-244 795.0
HFD2_k127_5241373_2 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 554.0
HFD2_k127_5241373_3 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001041 258.0
HFD2_k127_5241373_4 - - - - 0.0000000000001521 80.0
HFD2_k127_5246683_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008976 496.0
HFD2_k127_5246683_1 competence protein COMEC K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 364.0
HFD2_k127_5246683_2 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007961 245.0
HFD2_k127_5246683_3 - - - - 0.00000000000000000000000000000000000000000000004379 182.0
HFD2_k127_5246683_4 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000768 151.0
HFD2_k127_5246683_5 - - - - 0.0000000000000000000000000000128 134.0
HFD2_k127_5246683_6 positive regulation of proteasomal protein catabolic process - GO:0001763,GO:0002009,GO:0003401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0006950,GO:0007275,GO:0008150,GO:0009653,GO:0009791,GO:0009887,GO:0009888,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010468,GO:0010604,GO:0012505,GO:0019222,GO:0030154,GO:0030162,GO:0030323,GO:0030324,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0033554,GO:0034976,GO:0035239,GO:0035295,GO:0040007,GO:0042176,GO:0042692,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045732,GO:0045862,GO:0048286,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048729,GO:0048731,GO:0048747,GO:0048754,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051146,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051716,GO:0055001,GO:0055002,GO:0060255,GO:0060425,GO:0060429,GO:0060441,GO:0060447,GO:0060541,GO:0060560,GO:0060562,GO:0060602,GO:0061061,GO:0061136,GO:0061138,GO:0065007,GO:0080090,GO:1901800,GO:1903050,GO:1903052,GO:1903362,GO:1903364 - 0.0001635 54.0
HFD2_k127_5277396_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.81e-266 850.0
HFD2_k127_5277396_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 513.0
HFD2_k127_5277396_2 electron transfer activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 467.0
HFD2_k127_5277396_3 phosphoglycolate phosphatase activity K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000715 338.0
HFD2_k127_5277396_4 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000002201 176.0
HFD2_k127_5277396_5 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000001126 57.0
HFD2_k127_5291527_0 protein kinase activity K07180 GO:0003674,GO:0003824,GO:0004672,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0042594,GO:0043170,GO:0043412,GO:0043562,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - 0.0 1030.0
HFD2_k127_5291527_1 Belongs to the UPF0229 family K09786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005212 489.0
HFD2_k127_5291527_2 PFAM SpoVR like protein K06415 - - 0.0000000000000000000000000000000000000000000000000000000000000002545 233.0
HFD2_k127_5291527_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000001222 224.0
HFD2_k127_5291527_4 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000004523 176.0
HFD2_k127_5291527_5 - - - - 0.00000000000000000000000000000000000000000000002845 179.0
HFD2_k127_5338612_0 UDP-glucoronosyl and UDP-glucosyl transferase K16444 - 2.4.1.310 9.445e-195 615.0
HFD2_k127_5338612_1 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 526.0
HFD2_k127_5338612_10 - - - - 0.0000000000000000000000001484 118.0
HFD2_k127_5338612_11 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.000000000000000000004408 104.0
HFD2_k127_5338612_12 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.000000000000000000114 94.0
HFD2_k127_5338612_2 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 471.0
HFD2_k127_5338612_3 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007295 267.0
HFD2_k127_5338612_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000006762 254.0
HFD2_k127_5338612_5 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000006038 222.0
HFD2_k127_5338612_7 - - - - 0.000000000000000000000000000000000003569 144.0
HFD2_k127_5338612_8 PFAM aldo keto reductase - - - 0.00000000000000000000000000000003666 138.0
HFD2_k127_5338612_9 Lytic transglycosylase catalytic - - - 0.0000000000000000000000000009162 126.0
HFD2_k127_5389378_0 PFAM glycoside hydrolase family 3 domain protein K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009705 590.0
HFD2_k127_5389378_1 Periplasmic copper-binding protein (NosD) - - - 0.0000000000009736 78.0
HFD2_k127_5390280_0 PFAM glycoside hydrolase family 3 K05349 - 3.2.1.21 1.873e-258 823.0
HFD2_k127_5390280_1 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000857 503.0
HFD2_k127_5390280_10 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000006445 155.0
HFD2_k127_5390280_11 - - - - 0.00000000000000000000000000000000007478 143.0
HFD2_k127_5390280_12 L,D-transpeptidase catalytic domain - - - 0.000000000000000000001877 109.0
HFD2_k127_5390280_13 YtxH-like protein - - - 0.000000000000000000571 97.0
HFD2_k127_5390280_14 HAMP domain - - - 0.0000000000002116 79.0
HFD2_k127_5390280_2 Phosphoglucose isomerase K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 453.0
HFD2_k127_5390280_3 DALR_2 K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 447.0
HFD2_k127_5390280_4 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 321.0
HFD2_k127_5390280_5 mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000000000000000000000000000000186 224.0
HFD2_k127_5390280_6 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000004309 203.0
HFD2_k127_5390280_7 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - 0.00000000000000000000000000000000000000000000000002472 187.0
HFD2_k127_5390280_8 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000001245 184.0
HFD2_k127_5390280_9 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000006366 185.0
HFD2_k127_5407843_0 H( )-stimulated, divalent metal cation uptake system K03322 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 546.0
HFD2_k127_5407843_1 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 537.0
HFD2_k127_5407843_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002807 230.0
HFD2_k127_5407843_3 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000000007992 212.0
HFD2_k127_5407843_4 Copper binding proteins, plastocyanin/azurin family K02638 - - 0.000000000000002219 83.0
HFD2_k127_5407843_5 Proton-conducting membrane transporter - - - 0.00000006457 62.0
HFD2_k127_5407843_6 - K05747,K20521 - - 0.00002121 55.0
HFD2_k127_5414986_0 polygalacturonase activity K01184 - 3.2.1.15 1.913e-200 636.0
HFD2_k127_5414986_1 ROK family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 543.0
HFD2_k127_5414986_2 unsaturated chondroitin disaccharide hydrolase activity K15532 - 3.2.1.172 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008208 464.0
HFD2_k127_5414986_3 Domain of unknown function (DUF4861) K01051 - 3.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 391.0
HFD2_k127_5414986_4 KR domain K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 364.0
HFD2_k127_5414986_5 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate K01815 - 5.3.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 364.0
HFD2_k127_5431741_0 Helix-hairpin-helix motif K02337 - 2.7.7.7 0.0 1406.0
HFD2_k127_5431741_1 Elongation factor G C-terminus K06207 - - 1.349e-282 882.0
HFD2_k127_5431741_2 tRNA synthetases class I (M) K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 523.0
HFD2_k127_5431741_3 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 388.0
HFD2_k127_5431741_4 PSP1 C-terminal conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 305.0
HFD2_k127_5431741_5 cation diffusion facilitator family transporter K16264 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001002 279.0
HFD2_k127_5431741_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000002445 202.0
HFD2_k127_5431741_7 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000003598 154.0
HFD2_k127_5431741_8 C-terminal, D2-small domain, of ClpB protein - - - 0.0000743 53.0
HFD2_k127_5459367_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 5.85e-280 873.0
HFD2_k127_5459367_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K16881 - 2.7.7.13,5.4.2.8 8.875e-227 745.0
HFD2_k127_5459367_10 - - - - 0.00000000193 68.0
HFD2_k127_5459367_2 penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 423.0
HFD2_k127_5459367_3 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 397.0
HFD2_k127_5459367_4 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008309 377.0
HFD2_k127_5459367_5 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 333.0
HFD2_k127_5459367_6 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000226 265.0
HFD2_k127_5459367_7 - - - - 0.000000000000000000000000000132 132.0
HFD2_k127_5459367_8 D,D-heptose 1,7-bisphosphate phosphatase K02841,K02843,K02849,K03271,K03272,K03273 - 2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28 0.000000000000000000000002426 118.0
HFD2_k127_5459367_9 Permease - - - 0.000000001857 70.0
HFD2_k127_547578_0 Nucleoside recognition K06374 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006098 263.0
HFD2_k127_547578_1 Nucleoside recognition K06373 - - 0.00000000000000000000000000000000000000000000000000000000000000009336 229.0
HFD2_k127_547578_2 - - - - 0.00000000000000000000000000000000000000000006038 167.0
HFD2_k127_547578_3 MerR, DNA binding K19591 - - 0.000000000000000000000000000000001206 137.0
HFD2_k127_547578_4 PFAM blue (type 1) copper domain protein - - - 0.0000000007506 65.0
HFD2_k127_5484645_0 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 450.0
HFD2_k127_5484645_1 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 414.0
HFD2_k127_5491335_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 526.0
HFD2_k127_5491335_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00818 - 2.6.1.11 0.00000000000000000000000000000000000000000000000000000000000000000007869 236.0
HFD2_k127_5491335_2 PFAM GCN5-related N-acetyltransferase K00619 - 2.3.1.1 0.000000000000000000000001618 113.0
HFD2_k127_5493766_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 440.0
HFD2_k127_5493766_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000009099 191.0
HFD2_k127_5493766_2 Lrp/AsnC ligand binding domain - - - 0.000000000000000000001665 98.0
HFD2_k127_5493766_3 PUCC protein - - - 0.0000000000000000006074 102.0
HFD2_k127_5507418_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 4.635e-296 925.0
HFD2_k127_5507418_1 alpha-L-arabinofuranosidase K01209 - 3.2.1.55 1.927e-228 730.0
HFD2_k127_5507418_2 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 3.968e-195 628.0
HFD2_k127_5507418_3 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000006058 149.0
HFD2_k127_5507418_5 Bacterial regulatory proteins, tetR family - - - 0.00000000000003227 80.0
HFD2_k127_5507418_6 Protein of unknown function (DUF4231) - - - 0.00000000001125 73.0
HFD2_k127_5507887_0 trisaccharide binding - - - 3.479e-210 684.0
HFD2_k127_5507887_1 InterPro IPR010496 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 396.0
HFD2_k127_5507887_2 acetylesterase activity K01181 - 3.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 316.0
HFD2_k127_5507887_3 cAMP biosynthetic process K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004948 294.0
HFD2_k127_5507887_4 - K07112 - - 0.0000000000000000000000000000000000000000000000000006092 189.0
HFD2_k127_5507887_5 - K07112 - - 0.0000000000000000000000000000000000000000000000000008187 188.0
HFD2_k127_5534384_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 443.0
HFD2_k127_5534384_1 component I K01665 - 2.6.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 437.0
HFD2_k127_5534384_2 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000003177 253.0
HFD2_k127_5534384_3 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001592 257.0
HFD2_k127_5534384_4 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000000000008402 176.0
HFD2_k127_5534384_5 Aminotransferase K00826,K02619 - 2.6.1.42,4.1.3.38 0.000000000000000000000000000000000000001848 156.0
HFD2_k127_5534384_6 Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P) K09733 - 4.2.3.153 0.0000000000000000000000000000006955 137.0
HFD2_k127_5535945_0 HD domain - - - 0.000000000000000000000000000000000000000000000000000001142 205.0
HFD2_k127_5535945_1 regulation of single-species biofilm formation K13572,K13573 - - 0.000000000000000000000000000000000000000000000007661 190.0
HFD2_k127_5535945_2 DinB family - - - 0.000000000000000000000000001218 119.0
HFD2_k127_5535945_3 Trypsin-like peptidase domain - - - 0.00000000000000000000000001381 126.0
HFD2_k127_5535945_4 WYL domain K13573 - - 0.00000000000000000002459 104.0
HFD2_k127_5535945_6 SPFH domain-Band 7 family - - - 0.00001771 57.0
HFD2_k127_5545794_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 496.0
HFD2_k127_5545794_1 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 428.0
HFD2_k127_5545794_2 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 420.0
HFD2_k127_5545794_3 Peptidase, M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005786 311.0
HFD2_k127_5545794_4 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000000000000000005317 146.0
HFD2_k127_5572781_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 1.211e-215 676.0
HFD2_k127_5572781_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 405.0
HFD2_k127_5572781_2 Homoserine dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001601 279.0
HFD2_k127_5572781_3 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000002386 230.0
HFD2_k127_5572781_4 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000053 198.0
HFD2_k127_5572781_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.0000000000000000000000000000000000000000001521 176.0
HFD2_k127_5572781_6 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000023 150.0
HFD2_k127_5572781_7 Binds the 23S rRNA K02909 - - 0.0000000000000000000000001056 109.0
HFD2_k127_5572781_9 Control of competence regulator ComK, YlbF/YmcA - - - 0.00000000000000174 90.0
HFD2_k127_5583710_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 5.37e-253 797.0
HFD2_k127_5583710_1 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 590.0
HFD2_k127_5583710_10 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000202 230.0
HFD2_k127_5583710_11 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000221 188.0
HFD2_k127_5583710_12 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000000000000000000004162 141.0
HFD2_k127_5583710_13 Cell division protein FtsQ K03589 - - 0.00000000000000003915 96.0
HFD2_k127_5583710_14 Putative glutamine amidotransferase - - - 0.0000000000000004295 93.0
HFD2_k127_5583710_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 514.0
HFD2_k127_5583710_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 484.0
HFD2_k127_5583710_4 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 398.0
HFD2_k127_5583710_5 Mur ligase family, catalytic domain K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 391.0
HFD2_k127_5583710_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007375 329.0
HFD2_k127_5583710_7 PFAM glycoside hydrolase, family 10 K01181 - 3.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000003816 282.0
HFD2_k127_5583710_8 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001048 265.0
HFD2_k127_5583710_9 MazG nucleotide pyrophosphohydrolase domain K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000008383 236.0
HFD2_k127_5608891_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K15408 - 1.9.3.1 2.553e-277 866.0
HFD2_k127_5608891_1 Pyrrolo-quinoline quinone K00114 - 1.1.2.8 4.258e-264 826.0
HFD2_k127_5608891_2 Multicopper oxidase K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 392.0
HFD2_k127_5608891_3 metal ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 335.0
HFD2_k127_5608891_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K17223 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 333.0
HFD2_k127_5608891_5 Glutamine amidotransferase class-I K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000004402 249.0
HFD2_k127_5608891_6 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.0000000000000000000000000000000000000000000000147 179.0
HFD2_k127_5608891_7 cytochrome c oxidase, subunit III - - - 0.000000000000000000000000000000000000000000006701 173.0
HFD2_k127_5608891_8 CS domain K13993 - - 0.0000000000000000000005744 107.0
HFD2_k127_561117_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007977 495.0
HFD2_k127_561117_1 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 430.0
HFD2_k127_561117_2 Cell cycle protein K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 397.0
HFD2_k127_561117_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 335.0
HFD2_k127_561117_4 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000554 303.0
HFD2_k127_561117_5 rod shape-determining protein MreD K03571 - - 0.000000000002048 74.0
HFD2_k127_5615546_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1116.0
HFD2_k127_5615546_1 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 419.0
HFD2_k127_5615546_10 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000000000001807 197.0
HFD2_k127_5615546_11 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000006173 200.0
HFD2_k127_5615546_12 CheC-like family K03410 - - 0.00000000000000000000000000000000000000000000001791 192.0
HFD2_k127_5615546_13 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000000001696 135.0
HFD2_k127_5615546_14 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000000000000000007424 137.0
HFD2_k127_5615546_15 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000003563 137.0
HFD2_k127_5615546_16 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000133 138.0
HFD2_k127_5615546_17 PFAM CheW domain protein K03408 - - 0.00000000000000000000000000000503 135.0
HFD2_k127_5615546_18 Cold shock protein K03704 - - 0.000000000000000000005859 103.0
HFD2_k127_5615546_19 PFAM DivIVA family protein K04074 - - 0.0000000001424 72.0
HFD2_k127_5615546_2 Chemotaxis protein CheA K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004355 384.0
HFD2_k127_5615546_20 PFAM CheW domain protein K03408 - - 0.0000000005803 68.0
HFD2_k127_5615546_21 Roadblock/LC7 domain - - - 0.00000001068 66.0
HFD2_k127_5615546_22 Roadblock LC7 family protein K07131 - - 0.0002295 48.0
HFD2_k127_5615546_23 TPR Domain containing protein K12600 - - 0.0009806 51.0
HFD2_k127_5615546_3 Bacterial dnaA protein K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 378.0
HFD2_k127_5615546_4 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 365.0
HFD2_k127_5615546_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 355.0
HFD2_k127_5615546_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 301.0
HFD2_k127_5615546_7 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000001211 276.0
HFD2_k127_5615546_8 Small GTP-binding protein K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008475 262.0
HFD2_k127_5615546_9 protein-glutamate O-methyltransferase activity K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000654 259.0
HFD2_k127_5616093_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 1.943e-229 722.0
HFD2_k127_5616093_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 512.0
HFD2_k127_5616093_2 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002157 247.0
HFD2_k127_5616093_3 Response regulator receiver - - - 0.000000003531 68.0
HFD2_k127_5616133_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 571.0
HFD2_k127_5616133_1 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 556.0
HFD2_k127_5616133_10 Transposase - - - 0.0000000000000000000003366 100.0
HFD2_k127_5616133_11 Haem-binding domain - - - 0.00000000000000000001311 101.0
HFD2_k127_5616133_2 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005284 525.0
HFD2_k127_5616133_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 477.0
HFD2_k127_5616133_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 452.0
HFD2_k127_5616133_5 PFAM ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 349.0
HFD2_k127_5616133_6 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006027 260.0
HFD2_k127_5616133_7 PFAM Asparaginase K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000001746 206.0
HFD2_k127_5616133_8 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000004188 176.0
HFD2_k127_5616133_9 Thioesterase K07107 - - 0.0000000000000000000000000000000000000005552 158.0
HFD2_k127_5627195_0 ABC transporter transmembrane region K20344 - - 1.689e-215 698.0
HFD2_k127_5627195_1 SMART Elongator protein 3 MiaB NifB - - - 2.854e-214 680.0
HFD2_k127_5627195_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion K20345 - - 0.000000000000000000000000000000000001849 151.0
HFD2_k127_5627195_3 - - - - 0.00000000000000000004227 97.0
HFD2_k127_5627195_5 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000001716 77.0
HFD2_k127_5665406_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 485.0
HFD2_k127_5665406_1 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 329.0
HFD2_k127_5665406_10 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000003532 166.0
HFD2_k127_5665406_11 - - - - 0.0000000000000000001386 97.0
HFD2_k127_5665406_12 PFAM OsmC family protein - - - 0.0000000000000008665 87.0
HFD2_k127_5665406_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006392 335.0
HFD2_k127_5665406_3 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001053 291.0
HFD2_k127_5665406_4 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002775 296.0
HFD2_k127_5665406_5 of the alpha beta superfamily K06889 - - 0.000000000000000000000000000000000000000000000000000000002 210.0
HFD2_k127_5665406_6 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000000000000000000000000000000000000000000004198 185.0
HFD2_k127_5665406_7 TonB dependent receptor - - - 0.000000000000000000000000000000000000000009455 176.0
HFD2_k127_5665406_8 luxR family - - - 0.00000000000000000000000000000000000000001248 160.0
HFD2_k127_5665406_9 - - - - 0.00000000000000000000000000000000000002086 150.0
HFD2_k127_5690770_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 379.0
HFD2_k127_5690770_1 PFAM Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004965 278.0
HFD2_k127_5690770_10 Domain of unknown function (DUF362) - - - 0.0000000000000000002742 100.0
HFD2_k127_5690770_11 PRC-barrel domain - - - 0.00000000000000007349 86.0
HFD2_k127_5690770_12 protein kinase activity - - - 0.0000006392 61.0
HFD2_k127_5690770_14 COG0346 Lactoylglutathione lyase and related lyases K01759 - 4.4.1.5 0.0000413 53.0
HFD2_k127_5690770_2 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000003419 235.0
HFD2_k127_5690770_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000215 201.0
HFD2_k127_5690770_4 Cupin 2, conserved barrel - - - 0.000000000000000000000000000000000000000000000000001299 186.0
HFD2_k127_5690770_5 Peptidase M50B-like - - - 0.0000000000000000000000000000000003532 142.0
HFD2_k127_5690770_6 Bacterial Ig-like domain 2 - - - 0.000000000000000000000000000104 131.0
HFD2_k127_5690770_7 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000004063 114.0
HFD2_k127_5690770_8 Domain of unknown function (DUF4153) - - - 0.00000000000000000000000077 121.0
HFD2_k127_5690770_9 - - - - 0.00000000000000000000002921 113.0
HFD2_k127_5702033_0 transport - - - 3.514e-317 1006.0
HFD2_k127_5702033_1 PFAM ASPIC and UnbV - - - 4.361e-275 885.0
HFD2_k127_5702033_10 - - - - 0.000000000000000000000000000000000000000000000000000000000001734 224.0
HFD2_k127_5702033_11 phospholipase Carboxylesterase - - - 0.000000000000000000000000000000001822 145.0
HFD2_k127_5702033_12 TonB-dependent Receptor Plug Domain - - - 0.00000000000000000000000000002451 123.0
HFD2_k127_5702033_13 Phospholipid methyltransferase - - - 0.00000000000000000000000006793 114.0
HFD2_k127_5702033_14 TonB-linked outer membrane protein, SusC RagA family - - - 0.000000000001558 68.0
HFD2_k127_5702033_2 Glycosyl hydrolase family 3 C-terminal domain K05349 - 3.2.1.21 4.356e-222 724.0
HFD2_k127_5702033_3 thymidine kinase activity K00857,K21572 - 2.7.1.21 3.827e-207 661.0
HFD2_k127_5702033_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 532.0
HFD2_k127_5702033_5 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 394.0
HFD2_k127_5702033_6 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 332.0
HFD2_k127_5702033_7 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 324.0
HFD2_k127_5702033_8 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 295.0
HFD2_k127_5702033_9 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001244 282.0
HFD2_k127_571915_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 611.0
HFD2_k127_571915_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 569.0
HFD2_k127_571915_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 501.0
HFD2_k127_571915_3 PFAM NAD dependent epimerase dehydratase family K18981 - 1.1.1.203 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 422.0
HFD2_k127_571915_4 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 403.0
HFD2_k127_571915_5 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000002265 260.0
HFD2_k127_571915_7 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.0000001345 65.0
HFD2_k127_571915_8 Tetratricopeptide repeat - - - 0.0001619 53.0
HFD2_k127_5738403_0 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 374.0
HFD2_k127_5738403_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000716 295.0
HFD2_k127_5738403_2 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000001549 222.0
HFD2_k127_5763390_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 344.0
HFD2_k127_5763390_1 Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000000000003745 160.0
HFD2_k127_5763390_2 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000002298 152.0
HFD2_k127_5763390_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000004646 133.0
HFD2_k127_5763390_4 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000003276 108.0
HFD2_k127_5763390_5 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000008588 92.0
HFD2_k127_5763390_6 Yqey-like protein K09117 - - 0.0000000000000000005554 94.0
HFD2_k127_5763390_7 - - - - 0.000000000000008369 86.0
HFD2_k127_5763390_8 Sporulation related domain - - - 0.0000796 56.0
HFD2_k127_5773154_0 EamA-like transporter family K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009639 256.0
HFD2_k127_5773154_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000005983 221.0
HFD2_k127_5773154_2 phosphorelay sensor kinase activity K03406,K18143 - 2.7.13.3 0.00000000000000002079 97.0
HFD2_k127_5801929_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 2.715e-286 909.0
HFD2_k127_580260_0 cobalamin-transporting ATPase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 546.0
HFD2_k127_580260_1 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000001145 260.0
HFD2_k127_580260_2 Protein of unknown function (DUF1499) - - - 0.000000000000000000000000000000000000000000000000000000007067 208.0
HFD2_k127_580260_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000001422 183.0
HFD2_k127_5818053_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 561.0
HFD2_k127_5818053_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006275 473.0
HFD2_k127_5818053_2 Periplasmic binding protein domain K02058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 352.0
HFD2_k127_5818053_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 342.0
HFD2_k127_5818053_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 331.0
HFD2_k127_5818053_5 Histidine kinase K07644,K18351 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 308.0
HFD2_k127_5818053_6 Monosaccharide ABC transporter ATP-binding protein, CUT2 family K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000003454 278.0
HFD2_k127_5818053_7 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000007261 250.0
HFD2_k127_5818053_8 Putative regulatory protein - - - 0.00000000000003038 74.0
HFD2_k127_5829108_0 Argininosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 533.0
HFD2_k127_5829108_1 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 402.0
HFD2_k127_5829108_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001002 289.0
HFD2_k127_5829108_3 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002066 262.0
HFD2_k127_5829108_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000005474 184.0
HFD2_k127_5829108_5 Regulates arginine biosynthesis genes K03402 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006355,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901605,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000009803 136.0
HFD2_k127_5829108_6 Catalyzes the formation of N-acetyl-L-glutamate from acetyl-CoA and L-glutamate K00619 - 2.3.1.1 0.0000000000000000000000000008583 124.0
HFD2_k127_5829108_7 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.0000000000001126 81.0
HFD2_k127_5830647_0 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000000000000000000000000504 213.0
HFD2_k127_5830647_1 Aspartyl protease - - - 0.00000000000000000000000000000000000000005236 168.0
HFD2_k127_5830647_2 SnoaL-like domain - - - 0.00000000000000000000000000000001855 135.0
HFD2_k127_5830647_3 AraC-like ligand binding domain - - - 0.00000000000000000000000001288 116.0
HFD2_k127_5831038_0 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 349.0
HFD2_k127_5831038_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 329.0
HFD2_k127_5831038_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000007312 188.0
HFD2_k127_5831038_3 STAS domain K04749 - - 0.00000000000000000000000000000000000000000000001212 179.0
HFD2_k127_5831038_4 Histidine kinase-like ATPase domain - - - 0.0000000000000000000004409 104.0
HFD2_k127_5836225_0 Thiolase, C-terminal domain K00626,K07508 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 440.0
HFD2_k127_5836225_1 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005312 423.0
HFD2_k127_5836225_10 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000004455 153.0
HFD2_k127_5836225_11 Putative adhesin - - - 0.0000000000000000000000000005195 130.0
HFD2_k127_5836225_12 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000001585 101.0
HFD2_k127_5836225_13 - - - - 0.000000000000000007939 96.0
HFD2_k127_5836225_14 - - - - 0.0000000000000000387 84.0
HFD2_k127_5836225_15 - - - - 0.0000000000002628 81.0
HFD2_k127_5836225_16 Protein of unknown function (DUF3309) - - - 0.0000000000004846 75.0
HFD2_k127_5836225_17 TIGRFAM TonB family protein K03832 - - 0.00001689 56.0
HFD2_k127_5836225_18 - - - - 0.00002471 55.0
HFD2_k127_5836225_19 - - - - 0.0001686 48.0
HFD2_k127_5836225_2 Dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 361.0
HFD2_k127_5836225_20 Tetratricopeptide repeat - - - 0.0003471 53.0
HFD2_k127_5836225_3 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 317.0
HFD2_k127_5836225_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 314.0
HFD2_k127_5836225_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 314.0
HFD2_k127_5836225_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000328 261.0
HFD2_k127_5836225_7 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000005422 243.0
HFD2_k127_5836225_8 Histidine kinase K07675 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000003438 237.0
HFD2_k127_5836225_9 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000004382 163.0
HFD2_k127_5839799_0 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 491.0
HFD2_k127_5839799_1 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000009925 233.0
HFD2_k127_5839799_2 Thiol disulfide interchange protein K04084 - 1.8.1.8 0.000000000000000000000000000002491 125.0
HFD2_k127_5839799_3 DinB superfamily - - - 0.0000001055 62.0
HFD2_k127_5841762_0 alpha-glucuronidase activity K01235 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010383,GO:0010410,GO:0010413,GO:0016052,GO:0016787,GO:0016798,GO:0033939,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044260,GO:0045491,GO:0045493,GO:0071554,GO:0071704,GO:1901575,GO:2000886 3.2.1.139 0.0 1021.0
HFD2_k127_5841762_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 4.546e-275 855.0
HFD2_k127_5841762_2 xylulokinase activity K00848,K00854 - 2.7.1.17,2.7.1.5 1.18e-233 731.0
HFD2_k127_5841762_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01706 - 4.2.1.40 5.29e-220 690.0
HFD2_k127_5841762_4 xylose isomerase activity K01805 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 9.999e-205 643.0
HFD2_k127_5841762_5 FCD - - - 0.00000000000000000000000000000000000000000000007651 177.0
HFD2_k127_5851627_0 Sortilin, neurotensin receptor 3, - - - 0.0 1071.0
HFD2_k127_5851627_1 Amidase K01426 - 3.5.1.4 2.351e-203 647.0
HFD2_k127_5851627_10 Surface antigen K07277,K07278 - - 0.00000000000000000000000000000000000001431 167.0
HFD2_k127_5851627_11 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000001014 144.0
HFD2_k127_5851627_12 Part of a membrane complex involved in electron transport - - - 0.000000000000000000000000000003519 138.0
HFD2_k127_5851627_13 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000004504 89.0
HFD2_k127_5851627_14 - - - - 0.0000003835 57.0
HFD2_k127_5851627_2 PFAM Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 525.0
HFD2_k127_5851627_3 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 548.0
HFD2_k127_5851627_4 Part of a membrane complex involved in electron transport K03615 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 430.0
HFD2_k127_5851627_5 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 321.0
HFD2_k127_5851627_6 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000000000001305 242.0
HFD2_k127_5851627_7 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000802 231.0
HFD2_k127_5851627_8 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000125 178.0
HFD2_k127_5851627_9 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000000000001848 168.0
HFD2_k127_5856658_0 - - - - 0.00000000000000000000000004277 121.0
HFD2_k127_5856658_1 Belongs to the glycosyl hydrolase 13 family K01176 - 3.2.1.1 0.00000001509 65.0
HFD2_k127_5856835_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 542.0
HFD2_k127_5856835_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 413.0
HFD2_k127_5856835_2 Pfam Zn-finger in ubiquitin-hydrolases and other protein - - - 0.00000000000000000000000000000000000001051 148.0
HFD2_k127_58642_0 Belongs to the glycosyl hydrolase 31 family K01187,K01811 - 3.2.1.177,3.2.1.20 1.141e-261 835.0
HFD2_k127_58642_1 family 43 - - - 3.472e-250 791.0
HFD2_k127_58642_10 Glycoside hydrolase, family 2, TIM barrel K01190 - 3.2.1.23 0.00000000009769 66.0
HFD2_k127_58642_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000001013 64.0
HFD2_k127_58642_12 beta-D-xylosidase K05349,K15920 - 3.2.1.21,3.2.1.37 0.00002388 49.0
HFD2_k127_58642_2 Glycosyl hydrolase family 65, N-terminal domain K15923 - 3.2.1.51 2.972e-236 755.0
HFD2_k127_58642_3 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006554 548.0
HFD2_k127_58642_4 CarboxypepD_reg-like domain K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 527.0
HFD2_k127_58642_5 Putative esterase K07214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 432.0
HFD2_k127_58642_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 297.0
HFD2_k127_58642_7 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000001208 158.0
HFD2_k127_58642_8 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000003271 148.0
HFD2_k127_58642_9 Putative esterase - - - 0.000000000000000000000000003538 119.0
HFD2_k127_5864784_0 Glycine cleavage system P-protein K00281 - 1.4.4.2 0.0 1269.0
HFD2_k127_5864784_1 Acyl-CoA dehydrogenase, middle domain - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 4.146e-216 689.0
HFD2_k127_5864784_10 Biotin/lipoate A/B protein ligase family K03800 - 6.3.1.20 0.000000000000000000000000000000000000000128 165.0
HFD2_k127_5864784_11 Belongs to the eIF-2B alpha beta delta subunits family K03680 - - 0.0000000000000000000000000000000003332 144.0
HFD2_k127_5864784_12 COG2207 AraC-type DNA-binding domain-containing - - - 0.00003359 55.0
HFD2_k127_5864784_13 His Kinase A (phosphoacceptor) domain - - - 0.0003888 47.0
HFD2_k127_5864784_2 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 536.0
HFD2_k127_5864784_3 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 400.0
HFD2_k127_5864784_4 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 350.0
HFD2_k127_5864784_5 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002214 302.0
HFD2_k127_5864784_6 Peptidase, S8 S53 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001071 274.0
HFD2_k127_5864784_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000008038 254.0
HFD2_k127_5864784_8 Catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins - - - 0.0000000000000000000000000000000000000000000000000000000000000000074 231.0
HFD2_k127_5864784_9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000006298 171.0
HFD2_k127_5866710_0 hydrolase, family 65, central catalytic K15923 - 3.2.1.51 1.168e-299 950.0
HFD2_k127_5866710_1 Two component regulator propeller - - - 6.801e-264 853.0
HFD2_k127_5866710_2 phospholipase C K01114 - 3.1.4.3 1.877e-213 678.0
HFD2_k127_5866710_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 310.0
HFD2_k127_5866710_4 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000002229 247.0
HFD2_k127_5866710_5 - - - - 0.000000000000000000000003213 108.0
HFD2_k127_5866710_6 Response regulator receiver domain protein - - - 0.0000000002548 68.0
HFD2_k127_5872297_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1271.0
HFD2_k127_5872297_1 glutamine synthetase K01915 - 6.3.1.2 1.072e-309 965.0
HFD2_k127_5872297_10 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000001059 147.0
HFD2_k127_5872297_11 RF-1 domain K15034 - - 0.00000000000000000000000000000004814 130.0
HFD2_k127_5872297_12 membrane transporter protein K07090 - - 0.00000000000000000000000008462 121.0
HFD2_k127_5872297_13 - - - - 0.00000000000000000000001086 118.0
HFD2_k127_5872297_14 - - - - 0.000000000000000005453 97.0
HFD2_k127_5872297_15 ISXO2-like transposase domain - - - 0.0000004909 56.0
HFD2_k127_5872297_2 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 576.0
HFD2_k127_5872297_3 Putative RNA methylase family UPF0020 K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 379.0
HFD2_k127_5872297_4 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001248 278.0
HFD2_k127_5872297_5 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms K01992,K07027,K14205 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000003954 272.0
HFD2_k127_5872297_6 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000009243 250.0
HFD2_k127_5872297_7 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000000000005208 236.0
HFD2_k127_5872297_8 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.0000000000000000000000000000000000000000000000000001052 193.0
HFD2_k127_5872297_9 Tricorn protease C1 domain K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000251 193.0
HFD2_k127_5876199_0 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005323 256.0
HFD2_k127_5876199_1 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000397 255.0
HFD2_k127_5876199_2 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000006915 168.0
HFD2_k127_5876199_3 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.000000000000001104 91.0
HFD2_k127_5876199_4 MlaD protein K02067 - - 0.0003164 52.0
HFD2_k127_5878110_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006032 342.0
HFD2_k127_5881044_0 B12 binding domain - - - 7.508e-234 732.0
HFD2_k127_5881044_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K14126,K17993 GO:0003674,GO:0005488,GO:0005575,GO:0016151,GO:0032991,GO:0043167,GO:0043169,GO:0044569,GO:0046872,GO:0046914,GO:1902494 1.12.1.3,1.12.1.5,1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 330.0
HFD2_k127_5881044_2 Oxidoreductase NAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 309.0
HFD2_k127_5881044_3 4Fe-4S dicluster domain K17996 - 1.12.98.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006601 289.0
HFD2_k127_5881044_4 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000001369 216.0
HFD2_k127_5881044_5 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000003924 209.0
HFD2_k127_5881044_6 - - - - 0.000000000000000000000000000000000001069 153.0
HFD2_k127_5881044_7 Histidine kinase HAMP K02482 - 2.7.13.3 0.00000000000000000000006863 108.0
HFD2_k127_5881044_8 PFAM response regulator receiver - - - 0.00000000000000000001788 96.0
HFD2_k127_5881044_9 cheY-homologous receiver domain K07658 - - 0.0000000000000006226 83.0
HFD2_k127_5976291_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001401 270.0
HFD2_k127_5992097_0 Amidohydrolase family - - - 5.852e-211 677.0
HFD2_k127_5992097_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001025 255.0
HFD2_k127_5998779_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.528e-220 713.0
HFD2_k127_5998779_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 501.0
HFD2_k127_5998779_10 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000003455 59.0
HFD2_k127_5998779_11 Peptidase family M50 K11749 - - 0.0000001036 53.0
HFD2_k127_5998779_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 486.0
HFD2_k127_5998779_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K01876,K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 435.0
HFD2_k127_5998779_4 Sugar nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 325.0
HFD2_k127_5998779_5 Nucleotidyl transferase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 318.0
HFD2_k127_5998779_6 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006221 264.0
HFD2_k127_5998779_7 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000004551 207.0
HFD2_k127_5998779_8 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000002251 199.0
HFD2_k127_5998779_9 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000008277 136.0
HFD2_k127_6054761_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 531.0
HFD2_k127_6054761_1 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 501.0
HFD2_k127_6054761_10 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000000000000000000000004361 208.0
HFD2_k127_6054761_11 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000007729 190.0
HFD2_k127_6054761_12 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) - - - 0.000000000000000000000000000000000000000000000001283 183.0
HFD2_k127_6054761_13 Formate/nitrite transporter K21990 - - 0.00000000000000000000000000000000000000000009429 173.0
HFD2_k127_6054761_14 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000007697 167.0
HFD2_k127_6054761_15 Chaperone - - - 0.00000000000000000000000000000000000932 152.0
HFD2_k127_6054761_16 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000005338 139.0
HFD2_k127_6054761_17 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000007456 128.0
HFD2_k127_6054761_18 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000000002619 122.0
HFD2_k127_6054761_19 PFAM thioesterase superfamily protein K07107 - - 0.000000000000000000000001253 109.0
HFD2_k127_6054761_2 P-loop ATPase protein family K06958,K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 480.0
HFD2_k127_6054761_20 Transglycosylase associated protein - - - 0.000000000000000000000005328 106.0
HFD2_k127_6054761_21 OsmC-like protein K07397 - - 0.0000000000000000000006078 100.0
HFD2_k127_6054761_22 repeat-containing protein - - - 0.000000000001557 78.0
HFD2_k127_6054761_23 PFAM Appr-1-p processing domain protein - - - 0.000000000009297 77.0
HFD2_k127_6054761_24 Protein conserved in bacteria - - - 0.00000000008491 72.0
HFD2_k127_6054761_26 PFAM Methyltransferase type 11 - - - 0.00002424 55.0
HFD2_k127_6054761_3 COG2939 Carboxypeptidase C (cathepsin A) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 463.0
HFD2_k127_6054761_4 Putative ATP-binding cassette K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 448.0
HFD2_k127_6054761_5 Pyridoxal-dependent decarboxylase conserved domain K13745 - 4.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006433 424.0
HFD2_k127_6054761_6 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007799 379.0
HFD2_k127_6054761_7 usher protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 320.0
HFD2_k127_6054761_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008182 312.0
HFD2_k127_6054761_9 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000001631 207.0
HFD2_k127_6110053_0 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 358.0
HFD2_k127_6118831_0 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000007604 243.0
HFD2_k127_6128736_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 529.0
HFD2_k127_6128736_1 Elongation factor SelB winged helix 3 K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008942 464.0
HFD2_k127_6128736_10 PTS system sorbose subfamily IIB component K19507 - - 0.0000000000000000000000000000000000000001105 155.0
HFD2_k127_6128736_11 Pas domain K13069 - 2.7.7.65 0.0000000000000000000000000000000000000001363 169.0
HFD2_k127_6128736_12 PTS system mannose/fructose/sorbose family IID component K02796 - - 0.00000000000000000000000000000000003305 151.0
HFD2_k127_6128736_13 PTS HPr component phosphorylation site K11189 - - 0.00000000000000000000000008844 119.0
HFD2_k127_6128736_14 Carboxypeptidase - - - 0.0000000000000000000001354 103.0
HFD2_k127_6128736_15 cAMP biosynthetic process K12132 - 2.7.11.1 0.00000000000147 75.0
HFD2_k127_6128736_16 system, fructose subfamily IIA component K02793,K02794 - 2.7.1.191 0.0000000007859 65.0
HFD2_k127_6128736_17 PTS system K02795 - - 0.00000001209 64.0
HFD2_k127_6128736_18 C4-type zinc ribbon domain K07164 - - 0.0005356 50.0
HFD2_k127_6128736_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 432.0
HFD2_k127_6128736_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 415.0
HFD2_k127_6128736_4 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000003433 246.0
HFD2_k127_6128736_5 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000000000000000000000000000003145 235.0
HFD2_k127_6128736_6 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000005541 195.0
HFD2_k127_6128736_7 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000002808 200.0
HFD2_k127_6128736_8 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000001079 173.0
HFD2_k127_6128736_9 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000001187 169.0
HFD2_k127_6135401_0 Mo-co oxidoreductase dimerisation domain K17225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 500.0
HFD2_k127_6135401_1 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.00000000000000000000000000000000000000000000000000000000000006096 220.0
HFD2_k127_6141440_0 heat shock protein binding K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 361.0
HFD2_k127_6141440_1 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 323.0
HFD2_k127_6141440_10 lytic transglycosylase activity - - - 0.00000000000000001101 94.0
HFD2_k127_6141440_11 Gas vesicle synthesis protein GvpL/GvpF - - - 0.000000000001256 81.0
HFD2_k127_6141440_12 Gas vesicle synthesis protein GvpL/GvpF - - - 0.00000000005797 73.0
HFD2_k127_6141440_13 Gas vesicle protein - - - 0.0000002203 57.0
HFD2_k127_6141440_2 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 316.0
HFD2_k127_6141440_3 Acyl-CoA reductase (LuxC) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001387 284.0
HFD2_k127_6141440_4 Highly conserved protein containing a thioredoxin domain K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001871 265.0
HFD2_k127_6141440_5 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004115 257.0
HFD2_k127_6141440_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000006929 251.0
HFD2_k127_6141440_7 Gas vesicle protein K - - - 0.0000000000000000000000000000000212 131.0
HFD2_k127_6141440_8 - - - - 0.000000000000000000000000000004481 133.0
HFD2_k127_6165939_0 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 432.0
HFD2_k127_6165939_1 asparagine synthase - - - 0.000000000000000000000000000000000993 142.0
HFD2_k127_6176711_0 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 5.77e-289 914.0
HFD2_k127_6176711_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 5.38e-232 746.0
HFD2_k127_6176711_2 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 521.0
HFD2_k127_6176711_3 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 387.0
HFD2_k127_6176711_4 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000104 205.0
HFD2_k127_6176711_5 COG0739 Membrane proteins related to metalloendopeptidases K21472 - - 0.000000000000000000000000001787 127.0
HFD2_k127_6176711_6 - - - - 0.0000000000000000002788 94.0
HFD2_k127_6176711_7 DinB family - - - 0.000000000000004205 86.0
HFD2_k127_6176711_8 transcriptional regulator - - - 0.00000000001183 70.0
HFD2_k127_6176711_9 - - - - 0.000000108 61.0
HFD2_k127_6192275_0 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 354.0
HFD2_k127_6192275_1 Protein of unknown function (DUF1194) K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 327.0
HFD2_k127_6192275_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000001017 236.0
HFD2_k127_6192275_3 von Willebrand factor type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000001986 209.0
HFD2_k127_6192275_4 Oxygen tolerance - - - 0.000000000000000000000000000000000000268 156.0
HFD2_k127_6192275_5 Psort location CytoplasmicMembrane, score - - - 0.00000000008364 74.0
HFD2_k127_6192275_6 von Willebrand factor type A domain K07114 - - 0.0000000001463 72.0
HFD2_k127_6193296_0 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 430.0
HFD2_k127_6193296_1 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000005303 206.0
HFD2_k127_6193296_2 Tetratricopeptide repeat K08309 - - 0.000000000000000000000000000000000004392 158.0
HFD2_k127_6193296_3 PFAM TonB-dependent Receptor Plug Domain K02014 - - 0.000001543 59.0
HFD2_k127_6193296_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00001608 58.0
HFD2_k127_6205280_0 permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 326.0
HFD2_k127_6205280_1 PFAM glycoside hydrolase family 3 domain protein K05349 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000006205 265.0
HFD2_k127_6205280_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000001276 211.0
HFD2_k127_62064_0 beta-galactosidase activity K15855 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005576,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044238,GO:0071704,GO:1901575 3.2.1.165 0.0 1318.0
HFD2_k127_62064_1 Fibronectin type III-like domain K05349 - 3.2.1.21 6.329e-318 992.0
HFD2_k127_62064_11 Belongs to the peptidase S41A family K06399 - 3.4.21.116 0.000002943 60.0
HFD2_k127_62064_2 Fibronectin type III-like domain K05349 - 3.2.1.21 2.544e-246 779.0
HFD2_k127_62064_3 Amino acid permease K03294,K19540 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039 - 1.355e-237 742.0
HFD2_k127_62064_4 lysine biosynthetic process via aminoadipic acid - - - 6.29e-199 650.0
HFD2_k127_62064_5 Belongs to the glycosyl hydrolase 43 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 527.0
HFD2_k127_62064_6 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000003632 211.0
HFD2_k127_62064_7 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000000000000000000000007943 209.0
HFD2_k127_62064_8 hydrolase, family 3 K05349 - 3.2.1.21 0.00000000000000000003383 91.0
HFD2_k127_6225628_0 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 373.0
HFD2_k127_6225628_1 DinB superfamily K18912 - 1.14.99.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008465 364.0
HFD2_k127_6225628_2 PFAM metal-dependent phosphohydrolase HD sub domain K09163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 304.0
HFD2_k127_6225628_3 TonB-dependent Receptor Plug K16092 - - 0.000005234 56.0
HFD2_k127_6228525_0 DNA topoisomerase II activity K02469 - 5.99.1.3 6.832e-311 974.0
HFD2_k127_6228525_1 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 297.0
HFD2_k127_6228525_2 Threonine dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009079 278.0
HFD2_k127_6228525_3 Transposase - - - 0.00002359 55.0
HFD2_k127_6228949_0 TonB dependent receptor - - - 0.0 1227.0
HFD2_k127_6228949_1 epimerase K00491,K21572 - 1.14.14.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 565.0
HFD2_k127_6228949_10 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003436 284.0
HFD2_k127_6228949_11 SpoU rRNA Methylase family K03437 - - 0.0000000000000000000000000000000000000000000000000000004761 208.0
HFD2_k127_6228949_12 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000001023 169.0
HFD2_k127_6228949_13 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000001607 153.0
HFD2_k127_6228949_14 oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor K10672,K10794 - 1.21.4.1,1.21.4.2 0.0000000000000000000000000000000003189 139.0
HFD2_k127_6228949_15 Transcriptional regulator - - - 0.00000000000000000000000000002101 126.0
HFD2_k127_6228949_16 - - - - 0.0000000000006513 76.0
HFD2_k127_6228949_17 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000001537 75.0
HFD2_k127_6228949_19 - - - - 0.000001092 60.0
HFD2_k127_6228949_2 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008756 506.0
HFD2_k127_6228949_20 Pyridoxamine 5'-phosphate oxidase - - - 0.0007176 49.0
HFD2_k127_6228949_3 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 456.0
HFD2_k127_6228949_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 438.0
HFD2_k127_6228949_5 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 415.0
HFD2_k127_6228949_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006535 428.0
HFD2_k127_6228949_7 cell redox homeostasis K00382,K22364 - 1.8.1.4,1.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 345.0
HFD2_k127_6228949_8 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 343.0
HFD2_k127_6228949_9 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 313.0
HFD2_k127_6231019_0 ABC transporter substrate-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 437.0
HFD2_k127_6231019_1 transmembrane transport K02025,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 380.0
HFD2_k127_6231019_2 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006955 321.0
HFD2_k127_6254606_0 Multicopper oxidase K22348 - 1.16.3.3 2.855e-199 642.0
HFD2_k127_6254606_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 488.0
HFD2_k127_6254606_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 468.0
HFD2_k127_6254606_3 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 296.0
HFD2_k127_6254606_4 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000107 193.0
HFD2_k127_6254606_5 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.000000000000000000000000000000000000000007452 166.0
HFD2_k127_6254606_6 Protein of unknown function (DUF456) K09793 - - 0.00000000002955 71.0
HFD2_k127_6269567_0 Ketoacyl-synthetase C-terminal extension - - - 0.0 1881.0
HFD2_k127_6269567_1 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 1.066e-284 912.0
HFD2_k127_6269567_10 - - - - 0.000000000000000000000000000000000000000000000001887 188.0
HFD2_k127_6269567_11 - - - - 0.0000000000000000000000000000000000000000000002887 183.0
HFD2_k127_6269567_12 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000001258 145.0
HFD2_k127_6269567_13 peptidase activity - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0007275,GO:0007517,GO:0007528,GO:0008150,GO:0009987,GO:0016043,GO:0030016,GO:0030017,GO:0030018,GO:0031674,GO:0032501,GO:0032502,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0044422,GO:0044424,GO:0044444,GO:0044449,GO:0044464,GO:0048513,GO:0048731,GO:0048856,GO:0050808,GO:0061061,GO:0071840,GO:0099080,GO:0099081,GO:0099512 - 0.000000000000000000000000000000001207 145.0
HFD2_k127_6269567_14 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters - - - 0.0000000000000000007644 92.0
HFD2_k127_6269567_2 Glycogen debranching enzyme - - - 4.249e-239 773.0
HFD2_k127_6269567_3 acyl-CoA dehydrogenase activity - - - 4.256e-220 697.0
HFD2_k127_6269567_4 Trehalase K03931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 624.0
HFD2_k127_6269567_5 RNA-metabolising metallo-beta-lactamase K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 536.0
HFD2_k127_6269567_6 oligopeptide transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 527.0
HFD2_k127_6269567_7 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000874 504.0
HFD2_k127_6269567_8 Multicopper oxidase K00368 - 1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 424.0
HFD2_k127_6269567_9 extracellular polysaccharide biosynthetic process K13582 - - 0.00000000000000000000000000000000000000000000000000007739 211.0
HFD2_k127_6289415_0 PFAM ribonuclease II K01147 - 3.1.13.1 6.239e-219 687.0
HFD2_k127_6332092_0 Zn peptidase - - - 0.0000000000000000000000000000000000000000000000000000008336 208.0
HFD2_k127_6332092_1 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000000000000004277 164.0
HFD2_k127_6332092_2 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000000004174 158.0
HFD2_k127_6332092_3 ISXO2-like transposase domain - - - 0.00000000000000000000000000000000003956 147.0
HFD2_k127_6335738_0 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000007509 192.0
HFD2_k127_6335738_1 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000001019 180.0
HFD2_k127_6335738_2 bleomycin resistance protein - - - 0.000000000000000000000000000000003445 136.0
HFD2_k127_6335738_3 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000006789 136.0
HFD2_k127_6345898_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 2.268e-195 621.0
HFD2_k127_6364657_0 hydrolase family 65, central catalytic K01194,K01838,K04844,K05342 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0016787,GO:0030312,GO:0044464,GO:0071944 2.4.1.64,3.2.1.28,5.4.2.6 1.095e-267 848.0
HFD2_k127_6364657_1 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 593.0
HFD2_k127_6364657_2 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 588.0
HFD2_k127_6364657_3 Trehalose-phosphatase K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000038 254.0
HFD2_k127_6364657_4 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000001032 243.0
HFD2_k127_6364657_5 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003195 222.0
HFD2_k127_6364657_6 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000004862 248.0
HFD2_k127_6364657_7 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000000000000005903 210.0
HFD2_k127_6364657_8 DinB family - - - 0.0000000000000000000000000000000000000000000000005692 183.0
HFD2_k127_6364657_9 Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.000000000000000000000000000000000000000000000009363 175.0
HFD2_k127_6369728_0 Nitric oxide reductase K04561 - 1.7.2.5 9.367e-197 622.0
HFD2_k127_6369728_1 Cytochrome c K02305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 330.0
HFD2_k127_6369728_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000005328 132.0
HFD2_k127_6385472_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 499.0
HFD2_k127_6385472_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 461.0
HFD2_k127_6385472_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 376.0
HFD2_k127_6385472_3 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 364.0
HFD2_k127_6385472_4 Transcription elongation factor, N-terminal K03624 - - 0.0000000000000000000000000000000000000000000002979 171.0
HFD2_k127_6385472_5 Alpha amylase, catalytic domain K01176 - 3.2.1.1 0.0000000000000000000000508 104.0
HFD2_k127_6385472_6 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000004602 94.0
HFD2_k127_6385472_7 - - - - 0.000000002373 67.0
HFD2_k127_6399140_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 5.24e-257 801.0
HFD2_k127_6399140_1 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 357.0
HFD2_k127_6399140_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 321.0
HFD2_k127_6399140_3 N-Acetylmuramoyl-L-alanine amidase K13730 - - 0.00000000000000000000000000000000000000000000000000000000002783 212.0
HFD2_k127_6399140_4 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000006649 193.0
HFD2_k127_6399140_5 Alpha/beta hydrolase family - - - 0.00000000000000000000000000001348 130.0
HFD2_k127_6399140_6 Regulator of K07343 - - 0.000000000000000342 86.0
HFD2_k127_6399140_7 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00001221 55.0
HFD2_k127_6433382_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 546.0
HFD2_k127_6433382_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005965 436.0
HFD2_k127_6433382_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 318.0
HFD2_k127_6433382_3 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000649 256.0
HFD2_k127_6433382_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000006222 223.0
HFD2_k127_6433382_5 RNA-binding protein homologous to eukaryotic snRNP - - - 0.000000000000000000000000000000001931 149.0
HFD2_k127_6464943_0 chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 600.0
HFD2_k127_6464943_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 531.0
HFD2_k127_6464943_10 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 316.0
HFD2_k127_6464943_11 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009295 273.0
HFD2_k127_6464943_12 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000009957 170.0
HFD2_k127_6464943_13 Surface antigen K07277 - - 0.000000000000000000000000000000000000001576 169.0
HFD2_k127_6464943_14 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000003203 139.0
HFD2_k127_6464943_15 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000006244 141.0
HFD2_k127_6464943_16 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000007878 134.0
HFD2_k127_6464943_17 Preprotein translocase subunit YajC K03210 - - 0.0000000000000001035 85.0
HFD2_k127_6464943_18 PFAM YbbR family protein - - - 0.000000000003898 76.0
HFD2_k127_6464943_19 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000004886 74.0
HFD2_k127_6464943_2 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 473.0
HFD2_k127_6464943_20 EstX protein - - - 0.0000000001339 73.0
HFD2_k127_6464943_21 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.00000006397 65.0
HFD2_k127_6464943_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 432.0
HFD2_k127_6464943_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 397.0
HFD2_k127_6464943_5 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 390.0
HFD2_k127_6464943_6 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009073 364.0
HFD2_k127_6464943_7 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 357.0
HFD2_k127_6464943_8 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 346.0
HFD2_k127_6464943_9 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 333.0
HFD2_k127_6468881_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 6.842e-203 654.0
HFD2_k127_6468881_1 TIGRFAM N-acetyl sugar amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 524.0
HFD2_k127_6468881_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 346.0
HFD2_k127_6468881_3 Heparinase II/III N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 334.0
HFD2_k127_6468881_4 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 306.0
HFD2_k127_6468881_5 glutamine metabolic process K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001665 256.0
HFD2_k127_6468881_6 CobQ CobB MinD ParA nucleotide binding domain K16554,K16692 - - 0.00000000000000000000000000000000000000000000000000000000001371 233.0
HFD2_k127_6468881_7 polysaccharide export K01991 - - 0.00000000000000000000001375 108.0
HFD2_k127_6480945_0 Peptidase family M28 - - - 1.271e-194 619.0
HFD2_k127_6480945_1 PFAM ATP dependent DNA ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008269 395.0
HFD2_k127_6480945_10 - - - - 0.00000000000001762 81.0
HFD2_k127_6480945_11 alkyl hydroperoxide reductase K03386,K03564 - 1.11.1.15 0.00005941 48.0
HFD2_k127_6480945_2 Outer membrane protein beta-barrel family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008193 304.0
HFD2_k127_6480945_3 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000004025 233.0
HFD2_k127_6480945_4 4-phosphoerythronate dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001396 238.0
HFD2_k127_6480945_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000001866 212.0
HFD2_k127_6480945_6 ArsC family - - - 0.0000000000000000000000000000000000000001005 154.0
HFD2_k127_6480945_7 Domain of unknown function (DUF4112) - - - 0.0000000000000000000000000000009558 130.0
HFD2_k127_6480945_8 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000001344 94.0
HFD2_k127_6480945_9 aminopeptidase activity - - - 0.00000000000000006419 94.0
HFD2_k127_6494104_0 helicase activity - - - 0.0000000000000000000000000000000000000000000000000000008674 203.0
HFD2_k127_6494104_1 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000008054 120.0
HFD2_k127_6494104_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00184 - - 0.0000000000004753 72.0
HFD2_k127_6508092_0 SMART PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000004236 251.0
HFD2_k127_6508092_1 DNA methylase - - - 0.00000000000000000000000000000000000000000000000000005423 201.0
HFD2_k127_6508092_2 Protein of unknown function (DUF423) - - - 0.0000000000000000000000000000000000000003115 152.0
HFD2_k127_6537342_0 DHH family K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 454.0
HFD2_k127_6537342_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 432.0
HFD2_k127_6537342_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 386.0
HFD2_k127_6537342_3 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000007956 194.0
HFD2_k127_6537342_4 Zn-ribbon protein, possibly nucleic acid-binding K07164 - - 0.00000000000001988 84.0
HFD2_k127_6553980_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 430.0
HFD2_k127_6553980_1 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008493 372.0
HFD2_k127_6553980_2 - - - - 0.00000000000000000000003391 103.0
HFD2_k127_6589361_0 Sugar (and other) transporter K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 499.0
HFD2_k127_6589361_1 Biotin-lipoyl like K03543 - - 0.00000000000000000000000000000005738 134.0
HFD2_k127_6589361_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000006724 103.0
HFD2_k127_6589361_3 outer membrane efflux protein K03287 - - 0.0000000002184 73.0
HFD2_k127_6642714_0 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008155 342.0
HFD2_k127_6666390_0 Phosphoglycerate kinase K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 498.0
HFD2_k127_6666390_1 Transketolase, pyrimidine binding domain K00167,K11381,K21417 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009539 421.0
HFD2_k127_6666390_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000481 271.0
HFD2_k127_6666390_3 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000005329 128.0
HFD2_k127_6666390_4 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00658 - 2.3.1.61 0.000000000000000000000000006335 117.0
HFD2_k127_6666390_5 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000001796 100.0
HFD2_k127_6714720_0 4 iron, 4 sulfur cluster binding K03737 - 1.2.7.1 0.0 1382.0
HFD2_k127_6714720_1 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 5.178e-221 703.0
HFD2_k127_6714720_10 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000003602 207.0
HFD2_k127_6714720_11 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000322 173.0
HFD2_k127_6714720_12 Part of a membrane complex involved in electron transport - - - 0.000000000000000000000000000001041 139.0
HFD2_k127_6714720_2 Part of a membrane complex involved in electron transport K03615 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 459.0
HFD2_k127_6714720_3 Nitrite reductase, copper-dependent K00368,K08100 - 1.3.3.5,1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008534 368.0
HFD2_k127_6714720_4 Fe-S cluster K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 300.0
HFD2_k127_6714720_5 electron transfer activity K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001036 291.0
HFD2_k127_6714720_6 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000022 310.0
HFD2_k127_6714720_7 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002915 296.0
HFD2_k127_6714720_8 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000001016 238.0
HFD2_k127_6714720_9 Cytochrome c K00376,K02305,K17760 - 1.1.9.1,1.7.2.4 0.000000000000000000000000000000000000000000000000000000001531 214.0
HFD2_k127_6758045_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 376.0
HFD2_k127_6758045_1 cell division K03590,K18640 - - 0.0000000000000000000000000000000000000000001875 185.0
HFD2_k127_6758045_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity - - - 0.0000000000000000000000000000000000004052 164.0
HFD2_k127_6758045_3 Pyridine nucleotide-disulphide oxidoreductase domain protein - - - 0.0000000001188 66.0
HFD2_k127_6758045_4 PFAM OmpA MotB domain protein K02557 - - 0.000007876 57.0
HFD2_k127_6811437_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.335e-204 655.0
HFD2_k127_6811437_1 PFAM DHH family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 378.0
HFD2_k127_6811437_2 HIT domain K02503 - - 0.00000000000000000000000000000000006108 141.0
HFD2_k127_6811437_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000005115 122.0
HFD2_k127_6811437_4 conserved protein (DUF2203) - - - 0.00000000000000000000627 105.0
HFD2_k127_6811437_5 - - - - 0.000000000000000009066 93.0
HFD2_k127_6811437_6 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000008236 63.0
HFD2_k127_6812343_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 4.059e-207 663.0
HFD2_k127_6812343_1 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007782 315.0
HFD2_k127_6831486_0 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002936 258.0
HFD2_k127_6834501_0 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 322.0
HFD2_k127_6834501_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002902 273.0
HFD2_k127_6834501_2 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000004542 219.0
HFD2_k127_6834501_3 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000006348 201.0
HFD2_k127_6834501_4 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000004662 148.0
HFD2_k127_6834501_5 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000006213 141.0
HFD2_k127_6834501_6 activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation - - - 0.000000000105 74.0
HFD2_k127_68650_0 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 341.0
HFD2_k127_6870719_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 3.548e-270 847.0
HFD2_k127_6870719_1 Sigma-70 region 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008273 564.0
HFD2_k127_6870719_10 PHP domain protein K07053 - 3.1.3.97 0.0000000000000000000000001184 112.0
HFD2_k127_6870719_11 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000001455 94.0
HFD2_k127_6870719_2 ABC transporter transmembrane region K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 557.0
HFD2_k127_6870719_3 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 467.0
HFD2_k127_6870719_4 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001919 277.0
HFD2_k127_6870719_5 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000001215 275.0
HFD2_k127_6870719_6 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000004891 269.0
HFD2_k127_6870719_7 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000001211 156.0
HFD2_k127_6870719_8 Ferric uptake regulator family K03711 - - 0.0000000000000000000000000000000000002013 147.0
HFD2_k127_6870719_9 - - - - 0.0000000000000000000000000005131 127.0
HFD2_k127_6893327_0 L-glutamate biosynthetic process K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1817.0
HFD2_k127_6893327_1 'glutamate synthase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 394.0
HFD2_k127_6893327_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000001478 250.0
HFD2_k127_6893327_3 Domain of unknown function (DUF1906) - - - 0.000000000000000000006394 100.0
HFD2_k127_6899230_0 RecQ zinc-binding K03654 - 3.6.4.12 1.702e-210 674.0
HFD2_k127_6899230_1 Winged helix DNA-binding domain K09927 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 478.0
HFD2_k127_6899230_10 - - - - 0.0000000000004319 74.0
HFD2_k127_6899230_12 translation release factor activity - - - 0.0000004371 62.0
HFD2_k127_6899230_13 Yip1 domain - - - 0.000002227 59.0
HFD2_k127_6899230_2 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 306.0
HFD2_k127_6899230_3 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000002899 254.0
HFD2_k127_6899230_4 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000001698 213.0
HFD2_k127_6899230_5 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000002018 171.0
HFD2_k127_6899230_6 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000000000000009379 162.0
HFD2_k127_6899230_7 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000001345 150.0
HFD2_k127_6899230_8 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000005082 130.0
HFD2_k127_6899230_9 Cupin 2, conserved barrel domain protein - - - 0.00000000000000006364 84.0
HFD2_k127_6904581_0 TonB dependent receptor - - - 0.0 1077.0
HFD2_k127_6904581_1 epimerase K00329,K00356,K00491,K21572 - 1.14.14.47,1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 521.0
HFD2_k127_7022157_0 ABC1 family K03688 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 595.0
HFD2_k127_7022157_1 hydroxymethylglutaryl-CoA reductase K00021 - 1.1.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 534.0
HFD2_k127_7022157_10 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000002282 138.0
HFD2_k127_7022157_11 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress - - - 0.0000000000000000000000000008673 122.0
HFD2_k127_7022157_12 CGNR zinc finger - - - 0.000000000000000000000000006303 120.0
HFD2_k127_7022157_14 Protein of unknown function (DUF3224) - - - 0.000000000000000000007822 96.0
HFD2_k127_7022157_15 Belongs to the amidase family K01426 - 3.5.1.4 0.00000003088 60.0
HFD2_k127_7022157_2 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 510.0
HFD2_k127_7022157_3 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 511.0
HFD2_k127_7022157_4 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004797 468.0
HFD2_k127_7022157_5 D-alanine [D-alanyl carrier protein] ligase activity K00635 - 2.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 359.0
HFD2_k127_7022157_6 -O-antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001875 279.0
HFD2_k127_7022157_7 DoxX - - - 0.000000000000000000000000000000000000003623 159.0
HFD2_k127_7022157_8 Patatin-like phospholipase - - - 0.0000000000000000000000000000000002037 138.0
HFD2_k127_7022157_9 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000009019 144.0
HFD2_k127_7059543_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000429 276.0
HFD2_k127_7059543_1 Clp amino terminal domain, pathogenicity island component K03696 - - 0.00000000000000000795 89.0
HFD2_k127_7059543_2 DNA polymerase involved in DNA repair K14161 - - 0.00000000000007876 85.0
HFD2_k127_7059543_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553,K14160 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.00003504 55.0
HFD2_k127_7059737_0 ABC transporter transmembrane region K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 554.0
HFD2_k127_7059737_1 Domain of unknown function (DUF1707) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000003495 153.0
HFD2_k127_7074263_0 FIST C domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 539.0
HFD2_k127_7074263_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 503.0
HFD2_k127_7074263_2 phosphorelay sensor kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 340.0
HFD2_k127_7074263_3 Putative diguanylate phosphodiesterase K21023 - 2.7.7.65 0.0000000000000000000000000000000000000000000000009569 199.0
HFD2_k127_7074263_4 response to acidic pH K08996 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009268,GO:0009628,GO:0010447,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.000000000000000000000000000000000000000007789 163.0
HFD2_k127_7094494_0 Sigma-70 region 2 K03088 - - 0.000000000000000000000001499 117.0
HFD2_k127_7096050_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family K03406 - - 0.00000000000000000000000000000001168 138.0
HFD2_k127_7096050_1 polysaccharide deacetylase - - - 0.00000000000000000001586 98.0
HFD2_k127_7096050_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000008118 79.0
HFD2_k127_7108414_0 amino acid K03294 - - 1.715e-197 638.0
HFD2_k127_7108414_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 501.0
HFD2_k127_7108414_10 light absorption - - - 0.00000000000000000000000000000000266 142.0
HFD2_k127_7108414_11 - - - - 0.000000000000002233 85.0
HFD2_k127_7108414_2 C-terminus of AA_permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 357.0
HFD2_k127_7108414_3 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005173 276.0
HFD2_k127_7108414_4 Putative peptidoglycan binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001293 254.0
HFD2_k127_7108414_5 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000000000000007671 234.0
HFD2_k127_7108414_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000341 222.0
HFD2_k127_7108414_7 Methyltransferase small domain - - - 0.0000000000000000000000000000000000000003546 157.0
HFD2_k127_7108414_8 transcriptional - - - 0.000000000000000000000000000000000000002204 153.0
HFD2_k127_7108414_9 ABC transporter substrate-binding protein K01989 - - 0.00000000000000000000000000000000002833 144.0
HFD2_k127_7114182_0 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 519.0
HFD2_k127_7114182_1 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008239 503.0
HFD2_k127_7114182_10 Pfam:DUF59 K02612 - - 0.0000000000000000000000000005626 122.0
HFD2_k127_7114182_11 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000004414 114.0
HFD2_k127_7114182_12 Cold shock protein K03704 - - 0.0000000000000000000009853 101.0
HFD2_k127_7114182_13 - - - - 0.00000000001879 70.0
HFD2_k127_7114182_14 Phenylacetate-CoA oxygenase K02612 - - 0.00002064 51.0
HFD2_k127_7114182_2 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 446.0
HFD2_k127_7114182_3 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 413.0
HFD2_k127_7114182_4 Peptidase family M1 domain K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 388.0
HFD2_k127_7114182_5 phenylacetic acid catabolic K02609 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 393.0
HFD2_k127_7114182_6 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000572 209.0
HFD2_k127_7114182_7 Haloacid dehalogenase-like hydrolase K06019 - 3.6.1.1 0.000000000000000000000000000000000000000000000005033 187.0
HFD2_k127_7114182_8 PFAM phenylacetic acid catabolic family protein K02611 - 1.14.13.149 0.000000000000000000000000000000000415 144.0
HFD2_k127_7114182_9 Psort location Cytoplasmic, score 8.87 - - - 0.000000000000000000000000000008293 123.0
HFD2_k127_7122303_0 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000008604 188.0
HFD2_k127_7122303_1 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000007728 126.0
HFD2_k127_7122303_2 1,4-alpha-glucan branching enzyme activity K00700 - 2.4.1.18 0.000000004794 64.0
HFD2_k127_7122303_3 - - - - 0.000423 53.0
HFD2_k127_7134530_0 Heat shock 70 kDa protein K04043 - - 1.154e-262 824.0
HFD2_k127_7134530_1 Insulinase (Peptidase family M16) K07263 - - 4.278e-206 651.0
HFD2_k127_7134530_10 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001827 276.0
HFD2_k127_7134530_11 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006665 257.0
HFD2_k127_7134530_12 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000007957 248.0
HFD2_k127_7134530_13 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000004734 238.0
HFD2_k127_7134530_14 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000000000000000000000000003486 198.0
HFD2_k127_7134530_15 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000001106 146.0
HFD2_k127_7134530_16 - - - - 0.00001161 55.0
HFD2_k127_7134530_2 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 606.0
HFD2_k127_7134530_3 Peptidase, M16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 535.0
HFD2_k127_7134530_4 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 488.0
HFD2_k127_7134530_5 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 492.0
HFD2_k127_7134530_6 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 441.0
HFD2_k127_7134530_7 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 378.0
HFD2_k127_7134530_8 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 337.0
HFD2_k127_7134530_9 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000361 283.0
HFD2_k127_7146608_0 Belongs to the aldehyde dehydrogenase family K00294,K13821 - 1.2.1.88,1.5.5.2 1.431e-213 676.0
HFD2_k127_7146608_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 339.0
HFD2_k127_7146608_2 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000001715 232.0
HFD2_k127_7146608_3 - - - - 0.0000000000000000000000000000000000000000000000000000002716 201.0
HFD2_k127_7146608_4 - - - - 0.0000000000000000000000000000000000001187 155.0
HFD2_k127_7146608_5 PFAM nitrogen-fixing NifU domain protein - - - 0.0000000000000000000005069 97.0
HFD2_k127_714799_0 transferase activity, transferring glycosyl groups K05946,K16701 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008378,GO:0008610,GO:0008653,GO:0008921,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035250,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.187 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 316.0
HFD2_k127_714799_1 polysaccharide export K01991 - - 0.00000000000000000000000000000000002474 143.0
HFD2_k127_714799_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000001984 127.0
HFD2_k127_714799_3 extracellular polysaccharide biosynthetic process K16554,K16692 - - 0.000000000000000000000000001097 131.0
HFD2_k127_714799_4 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000001609 87.0
HFD2_k127_7182452_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 2.04e-289 917.0
HFD2_k127_7182452_1 Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 477.0
HFD2_k127_7182452_2 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 424.0
HFD2_k127_7182452_3 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 355.0
HFD2_k127_7182452_4 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001745 257.0
HFD2_k127_7182452_5 Bacterial Ig-like domain - - - 0.00000000000000000000000000001296 136.0
HFD2_k127_7182452_6 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000811 94.0
HFD2_k127_7182452_7 BON domain - - - 0.000000000002882 77.0
HFD2_k127_7182452_8 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00004165 46.0
HFD2_k127_7187742_0 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 374.0
HFD2_k127_7187742_1 Domain of unknown function (DUF4974) K07165 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002828 255.0
HFD2_k127_7187742_2 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000001777 190.0
HFD2_k127_7187742_3 - - - - 0.000000000000000000000000000000000000000000002924 176.0
HFD2_k127_7192273_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 537.0
HFD2_k127_7192273_1 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 443.0
HFD2_k127_7192273_10 - - - - 0.0000000000000000005128 97.0
HFD2_k127_7192273_11 Methyltransferase K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 - 0.000000000000000001326 98.0
HFD2_k127_7192273_12 - - - - 0.00001422 53.0
HFD2_k127_7192273_2 Tannase and feruloyl esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 429.0
HFD2_k127_7192273_3 NAD(P)H quinone oxidoreductase, PIG3 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004953 323.0
HFD2_k127_7192273_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 325.0
HFD2_k127_7192273_5 EamA-like transporter family K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000001174 253.0
HFD2_k127_7192273_6 diguanylate cyclase K02030,K06950,K16923 - - 0.0000000000000000000000000000000003251 149.0
HFD2_k127_7192273_7 - - - - 0.000000000000000000000000211 123.0
HFD2_k127_7192273_8 NUDIX domain - - - 0.00000000000000000008282 100.0
HFD2_k127_7192273_9 - - - - 0.000000000000000000155 98.0
HFD2_k127_7201960_0 E1-E2 ATPase K01533 - 3.6.3.4 1.591e-244 777.0
HFD2_k127_7201960_1 LysM domain K13735 GO:0005575,GO:0005623,GO:0007155,GO:0008150,GO:0009279,GO:0009405,GO:0009987,GO:0016020,GO:0019867,GO:0022610,GO:0030260,GO:0030312,GO:0030313,GO:0031589,GO:0031975,GO:0042710,GO:0043708,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944,GO:0090605 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009505 312.0
HFD2_k127_7201960_2 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002538 286.0
HFD2_k127_7201960_3 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000003693 241.0
HFD2_k127_7201960_4 - - - - 0.000000000000000001343 97.0
HFD2_k127_7202349_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 614.0
HFD2_k127_7202349_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 301.0
HFD2_k127_7202349_2 PFAM short-chain dehydrogenase reductase SDR - GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 - 0.000000000000000000000000000000000000000000000000000000000000000000000006853 257.0
HFD2_k127_7202349_3 N-acetylmuramoyl-L-alanine amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006814 244.0
HFD2_k127_7202349_4 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000004483 228.0
HFD2_k127_7202349_5 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000000000000000000000000001442 158.0
HFD2_k127_7202349_6 SnoaL-like domain - - - 0.000000000000000000000000000000000209 139.0
HFD2_k127_7202349_7 DNA polymerase K00986 - 2.7.7.49 0.000000000000000000000009019 107.0
HFD2_k127_7206003_0 Carboxyl transferase domain - - - 2.446e-234 738.0
HFD2_k127_7206003_1 Acyclic terpene utilisation family protein AtuA - - - 1.278e-202 644.0
HFD2_k127_7206003_10 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000000000000000000000000002218 226.0
HFD2_k127_7206003_11 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000009292 208.0
HFD2_k127_7206003_12 DinB family - - - 0.00000000000000000000000000000000000000000000000000000001028 218.0
HFD2_k127_7206003_13 Belongs to the enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000151 196.0
HFD2_k127_7206003_14 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000002069 203.0
HFD2_k127_7206003_15 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000003579 204.0
HFD2_k127_7206003_16 - - - - 0.000000000000000000000000000000000000001441 151.0
HFD2_k127_7206003_17 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000001316 144.0
HFD2_k127_7206003_18 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000513 132.0
HFD2_k127_7206003_2 Ribonuclease E/G family K08301 - - 4.841e-201 638.0
HFD2_k127_7206003_20 T-protein K14187 - 1.3.1.12,5.4.99.5 0.000000000006902 70.0
HFD2_k127_7206003_3 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 605.0
HFD2_k127_7206003_4 Belongs to the thiolase family K00626,K02615 - 2.3.1.174,2.3.1.223,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 504.0
HFD2_k127_7206003_5 Acyl-CoA dehydrogenase, C-terminal domain K18244 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 498.0
HFD2_k127_7206003_6 RecQ zinc-binding K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 473.0
HFD2_k127_7206003_7 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 375.0
HFD2_k127_7206003_8 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 306.0
HFD2_k127_7206003_9 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002109 287.0
HFD2_k127_7206083_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 526.0
HFD2_k127_7206083_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 518.0
HFD2_k127_7206083_2 Alpha-amylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 499.0
HFD2_k127_7206083_3 PFAM Amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 456.0
HFD2_k127_7206083_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 395.0
HFD2_k127_7206083_5 Beta-L-arabinofuranosidase, GH127 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 319.0
HFD2_k127_7206083_6 nucleic acid binding K03698 - - 0.00000000000000000000000000000000000000000000000000000000000007892 229.0
HFD2_k127_7206083_7 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000002899 209.0
HFD2_k127_7215997_0 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002683 269.0
HFD2_k127_7215997_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000002517 215.0
HFD2_k127_7215997_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000003086 168.0
HFD2_k127_7215997_3 OmpA family K03640 - - 0.0000000000000000000000000000000002501 152.0
HFD2_k127_7215997_4 TonB C terminal K03832 - - 0.000000000000000000000001139 113.0
HFD2_k127_7215997_5 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000008824 66.0
HFD2_k127_7216870_0 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007963 590.0
HFD2_k127_7216870_1 Belongs to the peptidase S1B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009908 503.0
HFD2_k127_7216870_2 Major facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008462 387.0
HFD2_k127_7216870_3 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001068 288.0
HFD2_k127_7216870_4 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.0000000000000000000000000000000000000000000000000000000000004902 226.0
HFD2_k127_7216870_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter - - - 0.00000000000000000000000000000000000000000002439 169.0
HFD2_k127_7216870_6 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000000000001853 86.0
HFD2_k127_7222319_0 PFAM glycoside hydrolase family 3 K05349 - 3.2.1.21 4.618e-242 768.0
HFD2_k127_7222319_1 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 486.0
HFD2_k127_7222319_10 cheY-homologous receiver domain K22010 - - 0.00000000000000000000000000000000000001087 153.0
HFD2_k127_7222319_11 RDD family - - - 0.00000000000000000000000000000000000002348 161.0
HFD2_k127_7222319_12 ECF sigma factor K03088 - - 0.0000000000000000000000000000000000001913 151.0
HFD2_k127_7222319_13 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000000000000000001491 130.0
HFD2_k127_7222319_14 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000005143 119.0
HFD2_k127_7222319_15 - - - - 0.0000000000000046 88.0
HFD2_k127_7222319_16 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.00000000004796 67.0
HFD2_k127_7222319_17 PFAM peptidase S1 and S6 chymotrypsin Hap K04771 - 3.4.21.107 0.0000000006208 71.0
HFD2_k127_7222319_18 Belongs to the peptidase S1C family K04691,K04772 - - 0.000000000823 71.0
HFD2_k127_7222319_19 Putative zinc-finger - - - 0.00003849 56.0
HFD2_k127_7222319_2 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 450.0
HFD2_k127_7222319_20 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.00006518 54.0
HFD2_k127_7222319_21 Domain of unknown function (DUF5057) - - - 0.0005739 51.0
HFD2_k127_7222319_3 phosphoglycerate mutase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006045 416.0
HFD2_k127_7222319_4 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 399.0
HFD2_k127_7222319_5 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 364.0
HFD2_k127_7222319_6 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 300.0
HFD2_k127_7222319_7 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 GO:0000166,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0008150,GO:0008152,GO:0008168,GO:0016740,GO:0016741,GO:0032259,GO:0036094,GO:0040007,GO:0042083,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050797,GO:0070402,GO:0097159,GO:1901265,GO:1901363 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000007117 244.0
HFD2_k127_7222319_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000003757 244.0
HFD2_k127_7222319_9 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000007392 238.0
HFD2_k127_72338_0 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 483.0
HFD2_k127_72338_1 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008265 309.0
HFD2_k127_72338_2 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000002217 189.0
HFD2_k127_72338_3 PFAM PRC-barrel domain - - - 0.0000000000000000000001855 101.0
HFD2_k127_72338_4 - - - - 0.00000000000000000895 92.0
HFD2_k127_7242985_0 Diguanylate cyclase, GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 300.0
HFD2_k127_7242985_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000286 263.0
HFD2_k127_7242985_2 - - - - 0.00000000000000000000000000008467 130.0
HFD2_k127_7242985_3 COG NOG14600 non supervised orthologous group - - - 0.00000000000000000007141 89.0
HFD2_k127_7242985_4 Trm112p-like protein K09791 - - 0.0000000000000000002708 87.0
HFD2_k127_7242985_5 - - - - 0.0001022 51.0
HFD2_k127_7267770_0 oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor K00311 GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204 1.5.5.1 6.28e-197 650.0
HFD2_k127_7267770_1 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 360.0
HFD2_k127_7267770_2 Electron transfer flavoprotein domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 317.0
HFD2_k127_7267770_3 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000001747 241.0
HFD2_k127_7267770_4 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000006239 201.0
HFD2_k127_7267770_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000007302 70.0
HFD2_k127_7267770_6 PFAM blue (type 1) copper domain protein - - - 0.000000001819 70.0
HFD2_k127_7282772_0 Belongs to the glycosyl hydrolase 31 family K01811 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.177 1.913e-309 977.0
HFD2_k127_7282772_1 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 313.0
HFD2_k127_7282772_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001508 282.0
HFD2_k127_7282772_3 - - - - 0.000000000008741 69.0
HFD2_k127_7286413_0 Class II Aldolase and Adducin N-terminal domain - - - 7.304e-267 837.0
HFD2_k127_7286413_1 Amidohydrolase family K06015 - 3.5.1.81 5.518e-221 707.0
HFD2_k127_7286413_10 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 415.0
HFD2_k127_7286413_11 enterobactin catabolic process K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 407.0
HFD2_k127_7286413_12 - K06905 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 402.0
HFD2_k127_7286413_13 Beta-lactamase class C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 327.0
HFD2_k127_7286413_14 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 294.0
HFD2_k127_7286413_15 COG1073 Hydrolases of the alpha beta superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002412 281.0
HFD2_k127_7286413_16 Protein of unknown function (DUF4255) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001663 274.0
HFD2_k127_7286413_17 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004474 252.0
HFD2_k127_7286413_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001145 248.0
HFD2_k127_7286413_19 Baseplate assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000003137 236.0
HFD2_k127_7286413_2 homolog of phage Mu protein gp47 - - - 6.742e-218 707.0
HFD2_k127_7286413_20 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000003402 245.0
HFD2_k127_7286413_21 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000112 210.0
HFD2_k127_7286413_22 T4-like virus tail tube protein gp19 - - - 0.00000000000000000000000000000000000000000000000000000000002133 206.0
HFD2_k127_7286413_23 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000002488 213.0
HFD2_k127_7286413_24 oxidation-reduction process K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000000000003903 199.0
HFD2_k127_7286413_26 - - - - 0.00000000000000000000000000000000000000000001827 172.0
HFD2_k127_7286413_27 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000002524 170.0
HFD2_k127_7286413_28 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000000000000000000000000006564 171.0
HFD2_k127_7286413_3 Baseplate J-like protein - - - 4.598e-201 659.0
HFD2_k127_7286413_30 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000002005 154.0
HFD2_k127_7286413_31 - - - - 0.0000000000000000000000000000000002846 142.0
HFD2_k127_7286413_32 GPW gp25 family protein K06903 - - 0.0000000000000000000000000001048 124.0
HFD2_k127_7286413_33 RibD C-terminal domain - - - 0.000000000000000000000000002366 114.0
HFD2_k127_7286413_34 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000004128 110.0
HFD2_k127_7286413_35 glyoxalase III activity - - - 0.000000000000000000000006731 112.0
HFD2_k127_7286413_36 response regulator - - - 0.000000000000000000001474 106.0
HFD2_k127_7286413_37 LysM domain - - - 0.000000000000000000002584 105.0
HFD2_k127_7286413_38 amine dehydrogenase activity - - - 0.000000000003087 81.0
HFD2_k127_7286413_39 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000003385 61.0
HFD2_k127_7286413_4 alpha-L-fucosidase K15923 - 3.2.1.51 8.258e-195 636.0
HFD2_k127_7286413_40 NYN domain - - - 0.000001602 58.0
HFD2_k127_7286413_41 Major Facilitator Superfamily - - - 0.000005871 52.0
HFD2_k127_7286413_42 NYN domain - - - 0.0008255 49.0
HFD2_k127_7286413_5 Phage tail sheath C-terminal domain K06907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 606.0
HFD2_k127_7286413_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 598.0
HFD2_k127_7286413_7 PFAM AAA ATPase central domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 537.0
HFD2_k127_7286413_8 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 523.0
HFD2_k127_7286413_9 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 462.0
HFD2_k127_7289851_0 Belongs to the glycosyl hydrolase 31 family K01811,K15922 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016787,GO:0016798,GO:0019637,GO:0034308,GO:0042180,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0061720,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901615,GO:1902776,GO:1902777,GO:1990929 3.2.1.177,3.2.1.199 3.287e-222 721.0
HFD2_k127_7289851_1 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001113 274.0
HFD2_k127_7289851_2 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004532 279.0
HFD2_k127_7289851_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000003883 239.0
HFD2_k127_7289851_4 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000001022 211.0
HFD2_k127_7289851_5 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000001403 230.0
HFD2_k127_7289851_6 COG0671 Membrane-associated phospholipid phosphatase - - - 0.000000000000000000000000000000000000000000000000000001687 208.0
HFD2_k127_7289851_7 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000005762 197.0
HFD2_k127_7289851_8 helix_turn_helix, Lux Regulon - - - 0.000001573 57.0
HFD2_k127_7291057_0 Major facilitator Superfamily K08178 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 563.0
HFD2_k127_7291057_1 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 403.0
HFD2_k127_7291057_10 oxidoreductase activity K07114 - - 0.000002203 59.0
HFD2_k127_7291057_11 PspA/IM30 family K03969 - - 0.0001883 52.0
HFD2_k127_7291057_2 Phospholipase D. Active site motifs. K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 339.0
HFD2_k127_7291057_3 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049,K15555 - - 0.00000000000000000000000000000000000000000000000000000000000000002887 236.0
HFD2_k127_7291057_4 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000002247 168.0
HFD2_k127_7291057_5 Amidohydrolase family - - - 0.0000000000000000000000000000000000000006979 152.0
HFD2_k127_7291057_6 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000007159 162.0
HFD2_k127_7291057_7 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000001598 137.0
HFD2_k127_7291057_8 Outer membrane protein beta-barrel domain - - - 0.000000000000000000000000001661 121.0
HFD2_k127_7291057_9 - - - - 0.0000000001503 72.0
HFD2_k127_7332243_0 UPF0365 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008614 407.0
HFD2_k127_7332243_1 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 369.0
HFD2_k127_7332243_2 Bacterial regulatory proteins, tetR family K09017 - - 0.00000000000000000000000000000000002056 143.0
HFD2_k127_7332243_3 COG1030 Membrane-bound serine protease (ClpP class) K07403 - - 0.0000000000000000000000000004797 122.0
HFD2_k127_7339086_0 xanthine dehydrogenase activity K03520 - 1.2.5.3 0.0 1060.0
HFD2_k127_7339086_1 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 325.0
HFD2_k127_7339086_2 xanthine dehydrogenase activity K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 306.0
HFD2_k127_7339086_3 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000001467 237.0
HFD2_k127_7339086_4 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000001735 213.0
HFD2_k127_7339086_5 SUF system FeS assembly protein, NifU family K04488 - - 0.00000000000000000000004784 106.0
HFD2_k127_7339086_6 Molybdopterin-guanine dinucleotide biosynthesis protein A K07141 - 2.7.7.76 0.00000001487 59.0
HFD2_k127_73584_0 Malate synthase K01638 - 2.3.3.9 5.457e-223 709.0
HFD2_k127_73584_1 PFAM isocitrate lyase and phosphorylmutase K01637 - 4.1.3.1 1.908e-200 641.0
HFD2_k127_73584_2 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 505.0
HFD2_k127_73584_3 peptidase activity K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 386.0
HFD2_k127_73584_4 - - - - 0.000000000000000000000000000000000000000000000003055 185.0
HFD2_k127_7362867_0 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 398.0
HFD2_k127_7362867_1 SNARE associated Golgi protein K01077 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 306.0
HFD2_k127_7362867_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 292.0
HFD2_k127_7362867_3 phosphatidate phosphatase activity K09474,K19302 - 3.1.3.2,3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002545 287.0
HFD2_k127_7362867_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000001078 264.0
HFD2_k127_7362867_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000009865 239.0
HFD2_k127_7362867_6 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 0.0000000000000000000000000000000000000000000000000001972 192.0
HFD2_k127_7362867_7 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000178 141.0
HFD2_k127_7362867_8 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000002522 85.0
HFD2_k127_7383833_0 Zinc-uptake complex component A periplasmic K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000335 283.0
HFD2_k127_7383833_1 COG1121 ABC-type Mn Zn transport systems ATPase component K11607,K11710 - - 0.000000000000000000000000000000000000000000000000000000000003444 229.0
HFD2_k127_7383833_2 phosphorelay signal transduction system K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000001335 231.0
HFD2_k127_7383833_3 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000000000004069 165.0
HFD2_k127_7383833_4 ABC-type Mn2 Zn2 transport systems permease components K02075,K09816 - - 0.000000000000000000000000000000000000004811 157.0
HFD2_k127_7383833_5 - - - - 0.000000000000000000000007259 117.0
HFD2_k127_7383833_7 Cupin 2, conserved barrel domain protein - - - 0.000000000003901 78.0
HFD2_k127_7383833_8 cAMP biosynthetic process - - - 0.0000000112 69.0
HFD2_k127_7392618_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 618.0
HFD2_k127_7392618_1 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 619.0
HFD2_k127_7392618_10 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000002437 243.0
HFD2_k127_7392618_11 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000003251 230.0
HFD2_k127_7392618_12 Dihydrodipicolinate synthetase family - - - 0.000000000000000000000000000000000000000000000000000000000001152 220.0
HFD2_k127_7392618_13 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000005327 224.0
HFD2_k127_7392618_14 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000162 175.0
HFD2_k127_7392618_16 MgtC family K07507 - - 0.000000000000000000000000000004977 126.0
HFD2_k127_7392618_17 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000001271 114.0
HFD2_k127_7392618_18 hydrocarbon binding protein (contains V4R domain) K07013 - - 0.0000009237 59.0
HFD2_k127_7392618_19 YtxH-like protein - - - 0.000284 51.0
HFD2_k127_7392618_2 Pyrimidine nucleoside phosphorylase C-terminal domain K00756 - 2.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 498.0
HFD2_k127_7392618_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 477.0
HFD2_k127_7392618_4 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 436.0
HFD2_k127_7392618_5 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 409.0
HFD2_k127_7392618_6 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 381.0
HFD2_k127_7392618_7 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 324.0
HFD2_k127_7392618_8 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 298.0
HFD2_k127_7392618_9 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate K00674,K05822 - 2.3.1.117,2.3.1.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002911 274.0
HFD2_k127_7406538_0 MacB-like periplasmic core domain K02004 - - 1.561e-238 773.0
HFD2_k127_7406538_1 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 420.0
HFD2_k127_7406538_2 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 415.0
HFD2_k127_7406538_3 mismatched DNA binding K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006101 392.0
HFD2_k127_7406538_4 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 291.0
HFD2_k127_7406538_5 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000001249 204.0
HFD2_k127_7406854_0 Voltage gated chloride channel - - - 8.9e-228 721.0
HFD2_k127_7406854_1 3-isopropylmalate dehydratase activity K01681,K01703,K01704,K17749 - 4.2.1.3,4.2.1.33,4.2.1.35 7.968e-216 702.0
HFD2_k127_7406854_2 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 575.0
HFD2_k127_7406854_3 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 456.0
HFD2_k127_7406854_4 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 376.0
HFD2_k127_7406854_5 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 358.0
HFD2_k127_7406854_6 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K11072 - 3.6.3.30,3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 323.0
HFD2_k127_7406854_7 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 315.0
HFD2_k127_7406854_8 DinB family - - - 0.00000000000000000000000000000000000001341 154.0
HFD2_k127_7450392_0 Hydrolase Family 16 - - - 1.095e-238 750.0
HFD2_k127_7450392_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 534.0
HFD2_k127_7450392_10 Protein of unknown function (DUF1706) - - - 0.000000002376 71.0
HFD2_k127_7450392_11 PFAM glycoside hydrolase, family 10 - - - 0.00009835 54.0
HFD2_k127_7450392_2 GDSL-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 469.0
HFD2_k127_7450392_3 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 431.0
HFD2_k127_7450392_4 ABC-type sugar transport system periplasmic component K02058,K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000105 285.0
HFD2_k127_7450392_5 ATPase domain of DNA mismatch repair MUTS family - - - 0.00000000000000000000000000000000000000000000000000000000000002514 231.0
HFD2_k127_7450392_6 Polymer-forming cytoskeletal - - - 0.000000000000000000000000002137 121.0
HFD2_k127_7450392_7 amine dehydrogenase activity - - - 0.0000000000000000000004318 113.0
HFD2_k127_7450392_8 Curli production assembly/transport component CsgG K04087 - - 0.000000000000000003238 98.0
HFD2_k127_7450392_9 secondary active sulfate transmembrane transporter activity - - - 0.00000000000000003521 95.0
HFD2_k127_7457348_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1377.0
HFD2_k127_7457348_1 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 3.311e-236 753.0
HFD2_k127_7457348_2 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 8.101e-228 709.0
HFD2_k127_7457348_3 SMART alpha amylase, catalytic sub domain K01187,K05343 - 3.2.1.1,3.2.1.20,5.4.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 491.0
HFD2_k127_7457348_4 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 406.0
HFD2_k127_7457348_5 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 355.0
HFD2_k127_7488809_0 peptidase K01415,K07386 - 3.4.24.71 6.87e-295 923.0
HFD2_k127_7488809_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006902 312.0
HFD2_k127_7488809_2 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001143 288.0
HFD2_k127_7488809_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000001441 106.0
HFD2_k127_7497087_0 GMC oxidoreductase K03333 - 1.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 576.0
HFD2_k127_7497087_1 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 462.0
HFD2_k127_7497087_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006598 273.0
HFD2_k127_7497087_3 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000001764 177.0
HFD2_k127_7497087_4 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000002577 132.0
HFD2_k127_7497087_5 cell redox homeostasis K01829,K03671 - 5.3.4.1 0.000000000000000000000000003706 121.0
HFD2_k127_7497087_6 - - - - 0.00000000000000006043 89.0
HFD2_k127_7497087_7 choline dehydrogenase activity K03333 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016614,GO:0016899,GO:0016995,GO:0044419,GO:0051704,GO:0055114 1.1.3.6 0.0000000000000000866 87.0
HFD2_k127_7497443_0 lysine biosynthetic process via aminoadipic acid - - - 0.0 1032.0
HFD2_k127_7497443_1 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009527 524.0
HFD2_k127_7497443_10 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000223 141.0
HFD2_k127_7497443_11 KaiB K08481 - - 0.0000000000000000000000000001492 118.0
HFD2_k127_7497443_12 - - - - 0.000009836 55.0
HFD2_k127_7497443_13 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000121 56.0
HFD2_k127_7497443_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 417.0
HFD2_k127_7497443_3 DeoC/LacD family aldolase K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 289.0
HFD2_k127_7497443_4 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000116 229.0
HFD2_k127_7497443_5 BlaR1 peptidase M56 - - - 0.000000000000000000000000000000000000000000007094 188.0
HFD2_k127_7497443_6 Penicillinase repressor - - - 0.0000000000000000000000000000000000000000001814 162.0
HFD2_k127_7497443_7 BAAT / Acyl-CoA thioester hydrolase C terminal K06889 - - 0.0000000000000000000000000000000000000009917 167.0
HFD2_k127_7497443_8 KaiB K08481 - - 0.0000000000000000000000000000000000002441 146.0
HFD2_k127_7497443_9 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000009466 155.0
HFD2_k127_7517659_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 490.0
HFD2_k127_7517659_1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000001995 181.0
HFD2_k127_7517659_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000008951 146.0
HFD2_k127_7517659_3 Response regulator receiver - - - 0.0000000000000000000001784 102.0
HFD2_k127_7517659_4 - - - - 0.000001031 59.0
HFD2_k127_7517659_5 energy transducer activity K03832 - - 0.00001017 47.0
HFD2_k127_7517659_6 - - - - 0.00001323 47.0
HFD2_k127_7517659_7 Recombinase zinc beta ribbon domain - - - 0.0002677 44.0
HFD2_k127_7517659_8 Domain present in PSD-95, Dlg, and ZO-1/2. K07177 - - 0.0005151 52.0
HFD2_k127_7517659_9 - - - - 0.00055 46.0
HFD2_k127_7518016_0 Glycosyl-hydrolase 97 C-terminal, oligomerisation - - - 8.342e-235 744.0
HFD2_k127_7518016_1 hydrolase activity, hydrolyzing O-glycosyl compounds - - - 6.239e-205 650.0
HFD2_k127_7518016_2 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 507.0
HFD2_k127_7518016_3 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 424.0
HFD2_k127_7518016_4 Glucose-fructose oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 397.0
HFD2_k127_7518016_5 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008874 349.0
HFD2_k127_7518016_7 Beta-lactamase - - - 0.0000000000000001692 85.0
HFD2_k127_7518016_8 PFAM phosphoesterase, PA-phosphatase related - - - 0.000000009063 66.0
HFD2_k127_7566213_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 3.122e-274 853.0
HFD2_k127_7566213_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 6.071e-207 680.0
HFD2_k127_7566213_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006238 529.0
HFD2_k127_7566213_3 TrkA-N domain K03316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 486.0
HFD2_k127_7566213_4 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 468.0
HFD2_k127_7566213_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005481 288.0
HFD2_k127_7566213_6 ACT domain K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000001322 203.0
HFD2_k127_7566213_7 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.1.1.86 0.00000000000000000000000000000000000002681 145.0
HFD2_k127_7566213_8 acetyltransferase K18815 - 2.3.1.82 0.000000000000000000009978 101.0
HFD2_k127_7574166_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 527.0
HFD2_k127_7574166_1 Sodium:dicarboxylate symporter family K11102 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 478.0
HFD2_k127_7574166_2 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 471.0
HFD2_k127_7574166_3 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 431.0
HFD2_k127_7574166_4 DinB superfamily K18912 - 1.14.99.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 340.0
HFD2_k127_7574166_5 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000003602 271.0
HFD2_k127_7574166_6 Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine K01919 - 6.3.2.2 0.000000000000000000000000000000000000000000009735 183.0
HFD2_k127_7578434_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 389.0
HFD2_k127_7578434_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 302.0
HFD2_k127_7578434_10 NmrA-like family - - - 0.000000000000006625 79.0
HFD2_k127_7578434_11 membrane-bound metal-dependent K07038 - - 0.00001443 54.0
HFD2_k127_7578434_2 Beta-eliminating lyase K00639,K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000002735 260.0
HFD2_k127_7578434_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000414 278.0
HFD2_k127_7578434_4 Beta-eliminating lyase K00639,K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000002469 251.0
HFD2_k127_7578434_5 LD-carboxypeptidase K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000002691 252.0
HFD2_k127_7578434_6 ATP cob(I)alamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000005283 192.0
HFD2_k127_7578434_7 3-beta hydroxysteroid dehydrogenase isomerase - - - 0.0000000000000000000000000000000000000000009792 164.0
HFD2_k127_7578434_8 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000001806 147.0
HFD2_k127_7578434_9 - - - - 0.0000000000000000000000003034 111.0
HFD2_k127_759995_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.372e-284 891.0
HFD2_k127_759995_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.836e-208 680.0
HFD2_k127_759995_10 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000002133 167.0
HFD2_k127_759995_11 rod shape-determining protein MreC K03570 - - 0.0000000000000000000000000000000000001336 154.0
HFD2_k127_759995_12 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000003375 123.0
HFD2_k127_759995_13 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000001965 119.0
HFD2_k127_759995_14 protein conserved in bacteria K09764 - - 0.0000000000000001558 85.0
HFD2_k127_759995_15 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000001243 78.0
HFD2_k127_759995_16 - - - - 0.00000000000209 73.0
HFD2_k127_759995_17 ribosomal protein - - - 0.0000000001985 68.0
HFD2_k127_759995_2 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 554.0
HFD2_k127_759995_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 557.0
HFD2_k127_759995_4 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 568.0
HFD2_k127_759995_5 Hsp70 protein K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004972 545.0
HFD2_k127_759995_6 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 427.0
HFD2_k127_759995_7 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 302.0
HFD2_k127_759995_8 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000741 237.0
HFD2_k127_759995_9 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.00000000000000000000000000000000000000000008194 169.0
HFD2_k127_7626691_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 578.0
HFD2_k127_7626691_1 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004359 514.0
HFD2_k127_7626691_2 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001167 266.0
HFD2_k127_7626691_3 GTP cyclohydrolase I K00950,K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000001268 273.0
HFD2_k127_7626691_4 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007248 263.0
HFD2_k127_7626691_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000004588 244.0
HFD2_k127_7626691_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000001659 140.0
HFD2_k127_7626691_7 hyperosmotic response - - - 0.00000000000000000000426 100.0
HFD2_k127_7664926_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 437.0
HFD2_k127_7664926_1 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008016 341.0
HFD2_k127_7664926_2 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006987 314.0
HFD2_k127_7664926_3 Transcriptional regulatory protein, C terminal K07657 - - 0.00000000000000000000000000000000000000000003025 172.0
HFD2_k127_7664926_4 Thioredoxin-like - - - 0.0000000000000000000000000000000000007902 147.0
HFD2_k127_7664926_5 EVE domain - - - 0.00000000000000000000000000000000001199 146.0
HFD2_k127_7665615_0 ImcF-related N-terminal domain K11891 - - 1.277e-219 722.0
HFD2_k127_7665615_1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 421.0
HFD2_k127_7665615_10 - - - - 0.0003895 51.0
HFD2_k127_7665615_2 Protein kinase domain K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000008213 279.0
HFD2_k127_7665615_3 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000001016 224.0
HFD2_k127_7665615_4 Type VI secretion system protein DotU K11892 - - 0.000000000000000000000000000000000000000000000000000004351 207.0
HFD2_k127_7665615_5 Bacterial Ig-like domain 2 - - - 0.00000000000000000000000000006754 133.0
HFD2_k127_7665615_6 Bacterial Ig-like domain 2 - - - 0.0000000000000000001464 97.0
HFD2_k127_7665615_7 Peptidoglycan-synthase activator LpoB - - - 0.0000000000000003817 92.0
HFD2_k127_7665615_8 (FHA) domain - - - 0.000000000005442 79.0
HFD2_k127_768264_0 Alpha amylase, C-terminal all-beta domain K00700 - 2.4.1.18 0.0 1125.0
HFD2_k127_768264_1 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009918 291.0
HFD2_k127_768264_2 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000000000000000000000000000000000000000004987 169.0
HFD2_k127_768264_3 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000001073 159.0
HFD2_k127_768264_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000007615 117.0
HFD2_k127_768264_5 glyoxalase III activity - - - 0.000000000000000000000003667 114.0
HFD2_k127_768264_6 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000399 53.0
HFD2_k127_7723906_0 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 498.0
HFD2_k127_7723906_1 Polysaccharide biosynthesis/export protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008969 495.0
HFD2_k127_7723906_10 -O-antigen - - - 0.00000000000000000000007059 115.0
HFD2_k127_7723906_2 Membrane protein involved in the export of O-antigen and teichoic acid K03328 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 425.0
HFD2_k127_7723906_3 PFAM NAD dependent epimerase dehydratase family K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 344.0
HFD2_k127_7723906_4 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000877 339.0
HFD2_k127_7723906_5 Capsule assembly protein Wzi - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003203 285.0
HFD2_k127_7723906_6 Regulator of chromosome condensation (RCC1) repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002438 265.0
HFD2_k127_7723906_7 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000708 213.0
HFD2_k127_7723906_8 Modulates the polysaccharide chain length of enterobacterial common antigen (ECA) - - - 0.00000000000000000000000000000000002096 150.0
HFD2_k127_7723906_9 Tetratricopeptide repeat - - - 0.000000000000000000000000000000006486 138.0
HFD2_k127_7749103_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002247 280.0
HFD2_k127_7763558_0 SERine Proteinase INhibitors K13963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 324.0
HFD2_k127_7763558_1 COG0491 Zn-dependent hydrolases, including glyoxylases K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000001655 259.0
HFD2_k127_7763558_2 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000004872 209.0
HFD2_k127_7763558_4 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000001381 209.0
HFD2_k127_7763558_5 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000001463 158.0
HFD2_k127_7763558_6 Sigma-70, region 4 K03088 - - 0.00000000000000000000000007767 115.0
HFD2_k127_7763558_7 - - - - 0.0000000000000000000306 96.0
HFD2_k127_7767685_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 416.0
HFD2_k127_7767685_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 353.0
HFD2_k127_7767685_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 325.0
HFD2_k127_7767685_3 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000000000000000000000003419 150.0
HFD2_k127_7767685_4 TIGRFAM DNA protecting protein DprA K04096 - - 0.0007204 44.0
HFD2_k127_7801805_0 transmembrane transporter activity K18138 - - 0.0 1556.0
HFD2_k127_7801805_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 4.075e-292 913.0
HFD2_k127_7801805_10 efflux transmembrane transporter activity K18300,K18308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 364.0
HFD2_k127_7801805_11 response regulator K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000002269 239.0
HFD2_k127_7801805_12 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000000000000000001133 203.0
HFD2_k127_7801805_13 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000004808 165.0
HFD2_k127_7801805_14 - - - - 0.00000000000000000000000000003995 130.0
HFD2_k127_7801805_15 - - - - 0.00000000000001248 87.0
HFD2_k127_7801805_17 Winged helix DNA-binding domain - - - 0.000000000449 66.0
HFD2_k127_7801805_2 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 3.262e-256 817.0
HFD2_k127_7801805_3 COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 3.367e-237 745.0
HFD2_k127_7801805_4 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 4.718e-227 717.0
HFD2_k127_7801805_5 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 499.0
HFD2_k127_7801805_6 Peptidase family S41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 484.0
HFD2_k127_7801805_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 394.0
HFD2_k127_7801805_8 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007045 392.0
HFD2_k127_7801805_9 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 377.0
HFD2_k127_7885684_0 metallopeptidase activity K01179 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0016052,GO:0016787,GO:0016798,GO:0033946,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0052736,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.4 2.839e-208 663.0
HFD2_k127_7885684_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000001539 226.0
HFD2_k127_7885684_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.00000000000000000000000000000000000000000000009633 177.0
HFD2_k127_7907609_0 PQQ enzyme repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 532.0
HFD2_k127_7907609_1 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 306.0
HFD2_k127_7907609_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000001344 232.0
HFD2_k127_7907609_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000000000000323 211.0
HFD2_k127_7907609_4 OsmC-like protein - - - 0.00000000000000000000000000000000000000000006359 173.0
HFD2_k127_7907609_5 acetyltransferase - - - 0.00000000000000000000000000000000003603 141.0
HFD2_k127_7907609_6 Domain of unknown function (DUF1772) - - - 0.00000000000000000000000000000001788 132.0
HFD2_k127_7907609_7 EF-hand domain pair - - - 0.000000000000000001033 96.0
HFD2_k127_7907609_8 Glucose / Sorbosone dehydrogenase - - - 0.0000000006671 72.0
HFD2_k127_791539_0 Protein of unknown function (DUF4038) - - - 1.076e-246 776.0
HFD2_k127_791539_1 Glycosyl hydrolases family 8 K15531 - 3.2.1.156 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 511.0
HFD2_k127_791539_10 SnoaL-like domain - - - 0.00000000000000000000000000000000000000005864 154.0
HFD2_k127_791539_11 - - - - 0.00000000000000000000000000000000000001943 157.0
HFD2_k127_791539_12 - - - - 0.000000000000000000000000000000000000299 146.0
HFD2_k127_791539_13 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000009013 147.0
HFD2_k127_791539_14 FG-GAP repeat protein - - - 0.000000000000000000000000000000002414 139.0
HFD2_k127_791539_15 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000000003844 123.0
HFD2_k127_791539_16 Aminoglycoside/hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.0000000000000000000000000004117 130.0
HFD2_k127_791539_17 DinB family - - - 0.0000000000000000000000000007611 119.0
HFD2_k127_791539_18 - - - - 0.000000000000000000000000005043 117.0
HFD2_k127_791539_19 lactoylglutathione lyase activity - - - 0.0000000000000000000000114 106.0
HFD2_k127_791539_2 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 306.0
HFD2_k127_791539_20 Gram-negative bacterial TonB protein C-terminal - - - 0.00000000000001105 85.0
HFD2_k127_791539_21 - - - - 0.000000003532 62.0
HFD2_k127_791539_22 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000001759 66.0
HFD2_k127_791539_23 - - - - 0.0000002511 56.0
HFD2_k127_791539_24 - - - - 0.0000007935 58.0
HFD2_k127_791539_25 - - - - 0.000005947 51.0
HFD2_k127_791539_3 PFAM bifunctional deaminase-reductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000001619 214.0
HFD2_k127_791539_4 methyltransferase activity K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000202 213.0
HFD2_k127_791539_5 methyltransferase K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000002707 210.0
HFD2_k127_791539_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07032 - - 0.0000000000000000000000000000000000000000000000000000000006877 214.0
HFD2_k127_791539_7 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000007242 190.0
HFD2_k127_791539_8 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000004994 171.0
HFD2_k127_791539_9 DinB family - - - 0.00000000000000000000000000000000000000004053 159.0
HFD2_k127_7924858_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 GO:0000731,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009927 587.0
HFD2_k127_7924858_1 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000004398 153.0
HFD2_k127_7924858_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K14161 - 2.7.7.7 0.000002425 55.0
HFD2_k127_7927340_0 Domain of unknown function (DUF5118) - - - 2.333e-228 745.0
HFD2_k127_7927340_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007869 297.0
HFD2_k127_7927340_2 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000000000000000000000000000000000000000001993 226.0
HFD2_k127_7927340_3 YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the K09780 - - 0.000000000000000000000000000000000000000004403 159.0
HFD2_k127_7927340_4 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000001031 115.0
HFD2_k127_7928205_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 310.0
HFD2_k127_7928205_1 Secretion protein K01993 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 313.0
HFD2_k127_7928205_2 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000002344 141.0
HFD2_k127_7928205_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000005359 77.0
HFD2_k127_7928205_4 Outer membrane efflux protein - - - 0.0000225 57.0
HFD2_k127_7951717_0 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 439.0
HFD2_k127_7951717_1 MatE K03327 - - 0.0000000000000000000000000000000000000000000000000592 188.0
HFD2_k127_79538_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 351.0
HFD2_k127_79538_1 N-terminal half of MaoC dehydratase K09709 - 4.2.1.153 0.0000000000000000000000000000000000000000000000000000000000000000192 239.0
HFD2_k127_79538_2 ErfK ybiS ycfS ynhG family protein K19234 - - 0.00000000000000000000000000000000000000008054 167.0
HFD2_k127_79538_3 phosphoenolpyruvate carboxylase activity K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.1.1.31 0.000004857 57.0
HFD2_k127_7959346_0 isomerase activity K01820 - 5.3.1.14 8.871e-218 684.0
HFD2_k127_7959346_1 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 566.0
HFD2_k127_7959346_2 xylulokinase activity K00848,K00854,K00879,K01813 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008993,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019200,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046365,GO:0046835,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901575 2.7.1.17,2.7.1.5,2.7.1.51,5.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 436.0
HFD2_k127_7959346_3 polygalacturonase activity K01184 - 3.2.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007053 436.0
HFD2_k127_7959346_4 carbohydrate binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 388.0
HFD2_k127_7959346_5 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 346.0
HFD2_k127_7959346_6 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 313.0
HFD2_k127_7959346_7 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000000002564 167.0
HFD2_k127_7959346_8 DinB superfamily - - - 0.0000000000000000000000000000000004261 145.0
HFD2_k127_7959346_9 Involved in the anomeric conversion of L-rhamnose K03534 - 5.1.3.32 0.0000000000000000000000000000006707 139.0
HFD2_k127_7990613_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000005696 219.0
HFD2_k127_7990613_1 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000000003061 217.0
HFD2_k127_7990613_2 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000009191 157.0
HFD2_k127_7995161_0 AcrB/AcrD/AcrF family K07787,K15726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 330.0
HFD2_k127_8047601_0 Lysylphosphatidylglycerol synthase TM region K07027,K14205 - 2.3.2.3 2.836e-295 932.0
HFD2_k127_8047601_1 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 6.464e-245 775.0
HFD2_k127_8047601_10 Aminoacyl-tRNA editing domain K19055 - - 0.00000000000000000000000000000000000000005077 162.0
HFD2_k127_8047601_11 - - - - 0.0000000000000001193 83.0
HFD2_k127_8047601_2 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007852 568.0
HFD2_k127_8047601_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 489.0
HFD2_k127_8047601_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006512 472.0
HFD2_k127_8047601_5 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 298.0
HFD2_k127_8047601_6 PFAM ROK family protein K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003647 287.0
HFD2_k127_8047601_7 Beta-lactamase K01256,K17836 - 3.4.11.2,3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001548 286.0
HFD2_k127_8047601_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002271 228.0
HFD2_k127_8047601_9 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000000000000002447 211.0
HFD2_k127_807674_0 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 554.0
HFD2_k127_8079283_0 secretion system protein K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 519.0
HFD2_k127_8079283_1 ATPase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 411.0
HFD2_k127_8079283_10 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000007422 207.0
HFD2_k127_8079283_11 PFAM Type II secretion system F K12511 - - 0.00000000000000000000000000000000000000000000000000008844 198.0
HFD2_k127_8079283_12 PFAM SAF domain K02279 - - 0.0000000000000000000000000000000000000000000006281 177.0
HFD2_k127_8079283_13 Flp pilus polar localization response receiver ATPase TadZ, FlhG domain-containing K02282 - - 0.000000000000000000000000000000000000000000001357 181.0
HFD2_k127_8079283_14 Type II secretion system K12510 - - 0.000000000000000000000000000000000000000000008678 186.0
HFD2_k127_8079283_15 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000307 165.0
HFD2_k127_8079283_16 amine dehydrogenase activity - - - 0.0000000000000000000000000000000003193 153.0
HFD2_k127_8079283_19 Putative zincin peptidase - - - 0.00000000000000000001826 99.0
HFD2_k127_8079283_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 325.0
HFD2_k127_8079283_20 - - - - 0.0000000000005816 81.0
HFD2_k127_8079283_21 PFAM TadE family protein - - - 0.000000000004264 76.0
HFD2_k127_8079283_22 peptidase A24A prepilin type IV K02278 - 3.4.23.43 0.000000007615 65.0
HFD2_k127_8079283_23 Flp/Fap pilin component - - - 0.00000001899 57.0
HFD2_k127_8079283_24 PFAM AIG2 family protein - - - 0.0000001562 57.0
HFD2_k127_8079283_25 Putative Flp pilus-assembly TadE/G-like - - - 0.0000001789 63.0
HFD2_k127_8079283_26 Flp/Fap pilin component - - - 0.0000004209 55.0
HFD2_k127_8079283_27 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000173 56.0
HFD2_k127_8079283_28 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0003904 53.0
HFD2_k127_8079283_3 Belongs to the GSP D family K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002692 297.0
HFD2_k127_8079283_4 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009811 280.0
HFD2_k127_8079283_5 COGs COG2912 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000527 254.0
HFD2_k127_8079283_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001683 250.0
HFD2_k127_8079283_7 COG1668 ABC-type Na efflux pump, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000003429 242.0
HFD2_k127_8079283_8 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000002809 233.0
HFD2_k127_8079283_9 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000005199 228.0
HFD2_k127_8121414_0 ABC transporter K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 354.0
HFD2_k127_8121414_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 359.0
HFD2_k127_8121414_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 302.0
HFD2_k127_8121414_3 - - - - 0.00000000000000000000000000000000000001507 161.0
HFD2_k127_8121414_4 Histidine kinase - - - 0.00000000000000000000000000002005 136.0
HFD2_k127_8121414_5 EamA-like transporter family K03298 - - 0.000000000000000000000618 112.0
HFD2_k127_8121414_6 - - - - 0.0001156 51.0
HFD2_k127_8121414_7 - - - - 0.000178 53.0
HFD2_k127_8138636_0 Methylene-tetrahydrofolate reductase C terminal K00297 - 1.5.1.20 1.567e-247 779.0
HFD2_k127_8138636_1 Nitrite and sulphite reductase 4Fe-4S domain K00392 - 1.8.7.1 2.689e-195 629.0
HFD2_k127_8138636_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 581.0
HFD2_k127_8138636_3 Belongs to the K00958,K13811 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007205 531.0
HFD2_k127_8138636_4 Tetrapyrrole (Corrin/Porphyrin) Methylases K01719,K01749,K02303,K13542,K13543 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,2.5.1.61,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 344.0
HFD2_k127_8138636_5 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000008311 236.0
HFD2_k127_8138636_6 Belongs to the PAPS reductase family. CysH subfamily K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000002499 235.0
HFD2_k127_8138636_8 sirohydrochlorin cobaltochelatase activity K03795 - 4.99.1.3 0.00000000000000000000000000000000000001737 162.0
HFD2_k127_8138636_9 membrane transporter protein K07090 - - 0.0000003206 63.0
HFD2_k127_8152395_0 NAD synthase K01916 - 6.3.1.5 1.299e-199 637.0
HFD2_k127_8152395_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 355.0
HFD2_k127_8152395_2 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001779 274.0
HFD2_k127_8152395_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000002294 187.0
HFD2_k127_8152395_4 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000003196 190.0
HFD2_k127_8152395_5 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000007789 183.0
HFD2_k127_8152395_6 LemA family K03744 - - 0.00000000000000000000000000000000000000000002051 175.0
HFD2_k127_8152395_8 - - - - 0.0000000000000000000008367 110.0
HFD2_k127_8152395_9 nucleotidyltransferase activity - - - 0.00000000000000000006842 98.0
HFD2_k127_8170726_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000001371 231.0
HFD2_k127_8170726_1 Helix-hairpin-helix motif K14162 - 2.7.7.7 0.000000000000000000000000000000000000000000009108 173.0
HFD2_k127_8170726_2 PFAM secretion protein HlyD family protein - - - 0.0000000000000000000000000000000000000293 157.0
HFD2_k127_8170726_3 Protein of unknown function (DUF3667) - - - 0.00000000000000000000000003867 119.0
HFD2_k127_8170726_4 - - - - 0.000000000000008914 82.0
HFD2_k127_8172675_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1135.0
HFD2_k127_8172675_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 4.014e-283 887.0
HFD2_k127_8172675_2 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000002409 242.0
HFD2_k127_8172675_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000006594 174.0
HFD2_k127_8172675_4 Outer membrane lipoprotein K05807 - - 0.0000000000000000000000000328 118.0
HFD2_k127_8172675_5 23S rRNA-intervening sequence protein - - - 0.00000000000002243 78.0
HFD2_k127_8172675_6 glycosyl transferase family 2 K20444 - - 0.000001192 57.0
HFD2_k127_8186240_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 323.0
HFD2_k127_8186240_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000002137 194.0
HFD2_k127_8186240_2 COGs COG0491 Zn-dependent hydrolase including glyoxylase - - - 0.000000000000000000000000000000000000000000000009978 179.0
HFD2_k127_8186240_3 hydrolase, HAD-superfamily, subfamily IIIA K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000257 173.0
HFD2_k127_8186240_4 Iron-sulphur cluster biosynthesis - - - 0.00000000000000000000000000000000000000008008 154.0
HFD2_k127_8186240_5 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00004165 46.0
HFD2_k127_8271682_0 transmembrane transporter activity K03296 - - 0.0 1221.0
HFD2_k127_8271682_1 nitrous-oxide reductase activity K00376,K02275 GO:0000041,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0030001,GO:0042597,GO:0044464,GO:0051179,GO:0051234 1.7.2.4,1.9.3.1 4.745e-308 962.0
HFD2_k127_8271682_10 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 344.0
HFD2_k127_8271682_11 HhH-GPD superfamily base excision DNA repair protein K01247,K13529 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 300.0
HFD2_k127_8271682_12 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000348 265.0
HFD2_k127_8271682_13 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001189 254.0
HFD2_k127_8271682_14 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000005066 227.0
HFD2_k127_8271682_15 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K19340 - - 0.00000000000000000000000000000000000000000000000000000001047 211.0
HFD2_k127_8271682_16 efflux transmembrane transporter activity K15725 - - 0.00000000000000000000000000000000000000000000000000000004552 217.0
HFD2_k127_8271682_17 lipoprotein involved in nitrous oxide reduction K19342 - - 0.0000000000000000000000000000000000000000000000000000003215 203.0
HFD2_k127_8271682_18 - - - - 0.0000000000000000000000000000000000000000000000005958 181.0
HFD2_k127_8271682_19 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000000000000000000000000006211 172.0
HFD2_k127_8271682_2 Oligoendopeptidase f - - - 1.309e-247 784.0
HFD2_k127_8271682_20 ABC-2 family transporter protein K19341 - - 0.00000000000000000000000000000000000000002855 173.0
HFD2_k127_8271682_21 TonB dependent receptor K16087 - - 0.00000000000000000000000000000000000001499 167.0
HFD2_k127_8271682_22 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000002083 141.0
HFD2_k127_8271682_23 Cytochrome C and Quinol oxidase polypeptide I K15862 - 1.9.3.1 0.0000000000000000000000000000002461 130.0
HFD2_k127_8271682_24 Predicted membrane protein (DUF2231) - - - 0.000000000000000000000000000003597 127.0
HFD2_k127_8271682_25 Cytochrome c K15862 - 1.9.3.1 0.000000000000000000000000000129 128.0
HFD2_k127_8271682_26 - - - - 0.0000000000000000000002544 106.0
HFD2_k127_8271682_27 lipoprotein involved in nitrous oxide reduction K19342 - - 0.000000000000000000007457 106.0
HFD2_k127_8271682_28 N-Acetylmuramoyl-L-alanine amidase - - - 0.00000000000000000006497 101.0
HFD2_k127_8271682_29 protein phosphatase 2C domain protein - - - 0.000000000009946 74.0
HFD2_k127_8271682_3 Trehalase K01194 - 3.2.1.28 2.903e-214 679.0
HFD2_k127_8271682_30 Cupin 2, conserved barrel domain protein - - - 0.000000002333 66.0
HFD2_k127_8271682_31 Domain of Unknown function (DUF542) K07322 - - 0.000004992 56.0
HFD2_k127_8271682_32 Cupin - - - 0.00003674 54.0
HFD2_k127_8271682_4 COG3263 NhaP-type Na H and K H K11105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 556.0
HFD2_k127_8271682_5 polysaccharide catabolic process K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 464.0
HFD2_k127_8271682_6 Periplasmic copper-binding protein (NosD) K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005918 420.0
HFD2_k127_8271682_7 unsaturated fatty acid biosynthetic process K04712 - 1.14.18.5,1.14.19.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 405.0
HFD2_k127_8271682_8 Pirin K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 356.0
HFD2_k127_8271682_9 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 347.0
HFD2_k127_8314905_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.819e-229 736.0
HFD2_k127_8314905_1 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000003167 265.0
HFD2_k127_8314905_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000001167 265.0
HFD2_k127_8314905_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000001054 211.0
HFD2_k127_8325111_0 peptidase K01389,K01415,K07386 - 3.4.24.11,3.4.24.71 2.649e-283 886.0
HFD2_k127_8325111_1 PFAM glycoside hydrolase family 39 K01198 - 3.2.1.37 2.559e-235 741.0
HFD2_k127_8325111_10 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000004161 215.0
HFD2_k127_8325111_11 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000001134 191.0
HFD2_k127_8325111_12 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000006053 199.0
HFD2_k127_8325111_13 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000002751 182.0
HFD2_k127_8325111_14 Acid phosphatase homologues - - - 0.0000000000000000000000000000000000000000001411 169.0
HFD2_k127_8325111_15 transporter K07238 - - 0.0000000000000000000000000000000000000000004769 175.0
HFD2_k127_8325111_16 FMN reductase (NADPH) activity - - - 0.0000000000000000000000000000000000000003662 158.0
HFD2_k127_8325111_17 - - - - 0.000000000000000000000000000000000006665 142.0
HFD2_k127_8325111_18 cheY-homologous receiver domain - - - 0.0000000000000001879 85.0
HFD2_k127_8325111_19 Predicted membrane protein (DUF2339) - - - 0.0000000000003057 83.0
HFD2_k127_8325111_2 oligopeptide transporter - - - 1.588e-203 662.0
HFD2_k127_8325111_20 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000005053 57.0
HFD2_k127_8325111_21 peptidyl-tyrosine sulfation K15773 - - 0.0000001174 57.0
HFD2_k127_8325111_3 Nitronate monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006744 544.0
HFD2_k127_8325111_4 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007258 458.0
HFD2_k127_8325111_5 Formamidopyrimidine-DNA glycosylase N-terminal domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 400.0
HFD2_k127_8325111_6 Aldo Keto reductase K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 388.0
HFD2_k127_8325111_7 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 300.0
HFD2_k127_8325111_8 B3 4 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003443 279.0
HFD2_k127_8325111_9 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000007481 246.0
HFD2_k127_8353032_0 Glycogen debranching enzyme - - - 1.6e-322 1013.0
HFD2_k127_8353032_1 Glycosyl hydrolase family 92 - - - 2.743e-286 902.0
HFD2_k127_8353032_10 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 420.0
HFD2_k127_8353032_11 Phosphodiester glycosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 406.0
HFD2_k127_8353032_12 inositol monophosphate 1-phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 380.0
HFD2_k127_8353032_13 Periplasmic binding protein LacI transcriptional regulator K02529,K05499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 374.0
HFD2_k127_8353032_14 monooxygenase, FAD-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 294.0
HFD2_k127_8353032_15 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001804 277.0
HFD2_k127_8353032_16 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000836 252.0
HFD2_k127_8353032_17 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source K03077 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000005395 265.0
HFD2_k127_8353032_18 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001649 235.0
HFD2_k127_8353032_19 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000001185 231.0
HFD2_k127_8353032_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 3.453e-264 824.0
HFD2_k127_8353032_20 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.0000000000000000000000000000000000000000000000000000000000000241 225.0
HFD2_k127_8353032_21 InterPro IPR014922 - - - 0.0000000000000000000000000000000000000000000000000000000001045 209.0
HFD2_k127_8353032_22 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000004145 213.0
HFD2_k127_8353032_23 - - - - 0.0000000000000000000000000000000000000000000000002378 196.0
HFD2_k127_8353032_24 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000001014 162.0
HFD2_k127_8353032_25 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000000000003526 148.0
HFD2_k127_8353032_26 - - - - 0.00000000000000000000000000000007282 128.0
HFD2_k127_8353032_27 Glycosyl hydrolase family 115 - - - 0.000000000000000000002689 99.0
HFD2_k127_8353032_28 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.0000000000000000363 96.0
HFD2_k127_8353032_3 Alpha-L-fucosidase K01206 - 3.2.1.51 2.016e-246 771.0
HFD2_k127_8353032_30 For insertion sequence element IS256 in transposon Tn4001 - - - 0.00000008941 58.0
HFD2_k127_8353032_32 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.0002934 48.0
HFD2_k127_8353032_4 Catalyzes the conversion of L-arabinose to L-ribulose K01804 - 5.3.1.4 5.638e-225 707.0
HFD2_k127_8353032_5 FGGY family of carbohydrate kinases, C-terminal domain K00853 - 2.7.1.16 1.254e-218 692.0
HFD2_k127_8353032_6 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 1.079e-194 622.0
HFD2_k127_8353032_7 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 524.0
HFD2_k127_8353032_8 Belongs to the AB hydrolase superfamily. MetX family K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 488.0
HFD2_k127_8353032_9 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 482.0
HFD2_k127_8364554_0 surface antigen K07278 - - 0.000000000000000007175 99.0
HFD2_k127_8391985_0 Class II Aldolase and Adducin N-terminal domain K00001,K01629 - 1.1.1.1,4.1.2.19 0.0 1094.0
HFD2_k127_8391985_1 Belongs to the binding-protein-dependent transport system permease family K10559,K10561 - - 6.061e-275 863.0
HFD2_k127_8391985_2 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10562 - 3.6.3.17 5.274e-200 634.0
HFD2_k127_8391985_3 LUD domain K18929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 600.0
HFD2_k127_8391985_4 Aldolase K01629 - 4.1.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009485 340.0
HFD2_k127_8391985_5 Belongs to the binding-protein-dependent transport system permease family K10560 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 327.0
HFD2_k127_8391985_6 Fe-S oxidoreductase K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000131 271.0
HFD2_k127_8391985_7 xylulokinase activity K00848,K00854,K00879,K01813 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008993,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019200,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046365,GO:0046835,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901575 2.7.1.17,2.7.1.5,2.7.1.51,5.3.1.14 0.0000000000000000000000000000000000003716 143.0
HFD2_k127_8393226_0 Belongs to the ABC transporter superfamily K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 354.0
HFD2_k127_8393226_1 PAS fold K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000988 175.0
HFD2_k127_8393226_2 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000006623 147.0
HFD2_k127_8393226_3 Major Facilitator Superfamily K03301 - - 0.00000000000167 82.0
HFD2_k127_8400974_0 ABC transporter transmembrane region K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 560.0
HFD2_k127_8400974_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K01663,K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 321.0
HFD2_k127_8400974_10 FR47-like protein K06976 - - 0.000000000000005079 76.0
HFD2_k127_8400974_11 Histidine biosynthesis protein K01814 - 5.3.1.16 0.000001979 49.0
HFD2_k127_8400974_2 EAL domain K13950,K21025 - 2.6.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007498 300.0
HFD2_k127_8400974_3 PFAM inositol monophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002316 286.0
HFD2_k127_8400974_4 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000008819 225.0
HFD2_k127_8400974_5 Histidine biosynthesis bifunctional protein HisIE K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000001175 200.0
HFD2_k127_8400974_6 EAL domain - - - 0.000000000000000000000000000000000000000000000006064 194.0
HFD2_k127_8400974_7 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000003632 175.0
HFD2_k127_8400974_8 Cell wall-active antibiotics response 4TMS YvqF - - - 0.0000000000000000000000000000000000000008086 158.0
HFD2_k127_8400974_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000006815 118.0
HFD2_k127_8410659_0 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 435.0
HFD2_k127_8495037_0 56kDa selenium binding protein (SBP56) K17285 - - 1.634e-227 714.0
HFD2_k127_8495037_1 PFAM Integral membrane protein TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 349.0
HFD2_k127_8495037_2 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 323.0
HFD2_k127_8495037_3 - - - - 0.000000000000000004034 91.0
HFD2_k127_85288_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 482.0
HFD2_k127_85288_1 Penicillin binding protein transpeptidase domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007665 451.0
HFD2_k127_85288_10 Cell division protein FtsQ K03589 - - 0.000000000000004934 85.0
HFD2_k127_85288_11 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000001425 65.0
HFD2_k127_85288_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 428.0
HFD2_k127_85288_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 414.0
HFD2_k127_85288_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 422.0
HFD2_k127_85288_5 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 319.0
HFD2_k127_85288_6 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 305.0
HFD2_k127_85288_7 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000876 312.0
HFD2_k127_85288_8 TIGRFAM stage V sporulation protein E, cell division protein FtsW K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000437 291.0
HFD2_k127_85288_9 Belongs to the MraZ family K03925 - - 0.00000000000000000006829 94.0
HFD2_k127_8562001_0 ABC-type transport system involved in Fe-S cluster assembly, permease component K09014 - - 1.294e-221 696.0
HFD2_k127_8562001_1 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 588.0
HFD2_k127_8562001_2 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 322.0
HFD2_k127_8562001_3 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000002993 250.0
HFD2_k127_8562001_4 4Fe-4S single cluster domain K07001 - - 0.000000000000000000000000000000000000000000000000002164 195.0
HFD2_k127_8562001_5 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000002202 167.0
HFD2_k127_8562001_6 Acid phosphatase homologues - - - 0.00000000000000000000000000000002048 136.0
HFD2_k127_8562001_7 peptidase K01295 - 3.4.17.11 0.000000000000007452 75.0
HFD2_k127_8572175_0 Peptidase family M3 K01414 - 3.4.24.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 538.0
HFD2_k127_8572175_1 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000008233 190.0
HFD2_k127_8572175_2 Putative metallopeptidase - - - 0.00000000000000000000000000000001199 138.0
HFD2_k127_8572175_3 choline dehydrogenase activity - - - 0.0000000000000000000006285 100.0
HFD2_k127_8591266_0 Sigma-54 interaction domain K15836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 370.0
HFD2_k127_8607073_0 ASPIC and UnbV - - - 0.0 1352.0
HFD2_k127_8607073_1 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 0.0 1022.0
HFD2_k127_8607073_10 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 447.0
HFD2_k127_8607073_11 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 417.0
HFD2_k127_8607073_12 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008204 402.0
HFD2_k127_8607073_13 Fumarate reductase, iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 348.0
HFD2_k127_8607073_14 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 298.0
HFD2_k127_8607073_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001062 276.0
HFD2_k127_8607073_16 electron transport chain K00347,K03614,K21163 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000005974 280.0
HFD2_k127_8607073_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000004962 262.0
HFD2_k127_8607073_18 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000139 226.0
HFD2_k127_8607073_19 succinate dehydrogenase K00241,K00247 - - 0.0000000000000000000000000000000000000000000000000000000844 204.0
HFD2_k127_8607073_2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 4.083e-318 1011.0
HFD2_k127_8607073_20 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000001338 204.0
HFD2_k127_8607073_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000003654 177.0
HFD2_k127_8607073_22 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000006722 183.0
HFD2_k127_8607073_23 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000000000006669 130.0
HFD2_k127_8607073_24 MoaE protein K21142 - 2.8.1.12 0.00000000000000000000000000000002242 131.0
HFD2_k127_8607073_25 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000001989 117.0
HFD2_k127_8607073_26 ECF sigma factor K03088 - - 0.000000000000000000000001748 113.0
HFD2_k127_8607073_27 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000003361 77.0
HFD2_k127_8607073_28 TOBE domain - - - 0.0000000000002092 72.0
HFD2_k127_8607073_29 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K21142 - 2.8.1.12 0.0000000007199 64.0
HFD2_k127_8607073_3 peptidyl-tyrosine sulfation - - - 3.118e-254 801.0
HFD2_k127_8607073_30 - - - - 0.00004961 52.0
HFD2_k127_8607073_4 peroxiredoxin activity - - - 6.017e-249 783.0
HFD2_k127_8607073_5 peptidyl-tyrosine sulfation - - - 2.993e-210 685.0
HFD2_k127_8607073_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 595.0
HFD2_k127_8607073_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000586 488.0
HFD2_k127_8607073_8 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 456.0
HFD2_k127_8607073_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 454.0
HFD2_k127_8628060_0 Phosphate acetyl/butaryl transferase K00027,K00029,K00625,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 2.496e-285 895.0
HFD2_k127_8628060_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 1.581e-208 660.0
HFD2_k127_8628060_10 - - - - 0.00000000000000000000000000000000000000000000001182 181.0
HFD2_k127_8628060_11 Methyltransferase domain - - - 0.000000000000000000000000000000000000000006295 167.0
HFD2_k127_8628060_12 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.0000000000000000000000000005104 131.0
HFD2_k127_8628060_13 domain, Protein - - - 0.0000000047 68.0
HFD2_k127_8628060_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000887 428.0
HFD2_k127_8628060_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 353.0
HFD2_k127_8628060_4 Amidohydrolase family K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 378.0
HFD2_k127_8628060_5 Putative esterase K07017 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 354.0
HFD2_k127_8628060_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 305.0
HFD2_k127_8628060_7 glycolate biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000007792 238.0
HFD2_k127_8628060_8 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000004328 217.0
HFD2_k127_8628060_9 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000002762 209.0
HFD2_k127_8628076_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 1.883e-270 854.0
HFD2_k127_8628076_1 TonB-dependent receptor - - - 9.64e-254 818.0
HFD2_k127_8628076_10 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007338 311.0
HFD2_k127_8628076_11 AAA domain K03546 - - 0.00000000000000000000000000000000000000000000000000000000002696 215.0
HFD2_k127_8628076_12 FCD - - - 0.000000000000000000000000000000000000000000000004434 190.0
HFD2_k127_8628076_13 Ribosomal protein L11 methyltransferase (PrmA) - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010565,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018023,GO:0018193,GO:0018205,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031974,GO:0031998,GO:0031999,GO:0032259,GO:0036211,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043414,GO:0043467,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045833,GO:0045922,GO:0046320,GO:0046322,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050994,GO:0050995,GO:0051341,GO:0051354,GO:0062012,GO:0062014,GO:0065007,GO:0065009,GO:0070013,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1904732,GO:1904733,GO:1904735,GO:1904736 - 0.0000000000000000000000000000000000000003537 159.0
HFD2_k127_8628076_14 23S rRNA-intervening sequence protein - - - 0.000000000000000001203 90.0
HFD2_k127_8628076_15 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 0.00000000000000000605 86.0
HFD2_k127_8628076_16 TonB dependent receptor - - - 0.0001315 52.0
HFD2_k127_8628076_2 Anthranilate synthase component I, N terminal region K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 512.0
HFD2_k127_8628076_3 Protein of unknown function (DUF2723) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 475.0
HFD2_k127_8628076_4 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007585 373.0
HFD2_k127_8628076_5 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000898 358.0
HFD2_k127_8628076_6 D-amino acid K21061 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007324 357.0
HFD2_k127_8628076_7 Proline racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 340.0
HFD2_k127_8628076_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 340.0
HFD2_k127_8628076_9 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714,K21062 - 3.5.4.22,4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 334.0
HFD2_k127_8656333_0 copper-translocating P-type ATPase K01533 - 3.6.3.4 2.388e-286 897.0
HFD2_k127_8656333_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 552.0
HFD2_k127_8656333_2 Predicted membrane protein (DUF2238) K08984 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 297.0
HFD2_k127_8656333_3 Histidine kinase K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000003745 243.0
HFD2_k127_8656333_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000001176 92.0
HFD2_k127_8656333_5 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000007673 84.0
HFD2_k127_8656333_6 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000004256 73.0
HFD2_k127_8656333_7 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0001903 52.0
HFD2_k127_8703940_0 Zn-dependent protease with chaperone function K03799,K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 383.0
HFD2_k127_8703940_1 endo-1,4-beta-xylanase activity K01181 - 3.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006363 342.0
HFD2_k127_8703940_10 PFAM Opioid growth factor receptor (OGFr) conserved region - - - 0.000000000000000000000000000000000003175 144.0
HFD2_k127_8703940_12 glyoxalase III activity - - - 0.00000000000000000000000000000000004634 141.0
HFD2_k127_8703940_13 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000002771 150.0
HFD2_k127_8703940_15 Sigma-70 region 2 K03088 - - 0.0000000000000000000003999 112.0
HFD2_k127_8703940_16 - - - - 0.00000000000000005934 85.0
HFD2_k127_8703940_19 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.0004185 47.0
HFD2_k127_8703940_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 339.0
HFD2_k127_8703940_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001807 234.0
HFD2_k127_8703940_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000003053 225.0
HFD2_k127_8703940_5 Beta-lactamase superfamily domain K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000002635 228.0
HFD2_k127_8703940_6 - - - - 0.000000000000000000000000000000000000000000000000000001795 195.0
HFD2_k127_8703940_7 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000001531 180.0
HFD2_k127_8703940_8 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000003109 153.0
HFD2_k127_8703940_9 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000001509 147.0
HFD2_k127_884534_0 Aromatic amino acid lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007832 529.0
HFD2_k127_884534_1 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 384.0
HFD2_k127_884534_2 Polyprenyl synthetase K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351 360.0
HFD2_k127_884534_3 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 340.0
HFD2_k127_884534_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000001379 174.0
HFD2_k127_884534_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000002212 71.0
HFD2_k127_884534_6 Domain of unknown function (DUF4321) - - - 0.00000000003235 68.0
HFD2_k127_884534_7 peptidyl-tyrosine sulfation - - - 0.000003594 61.0
HFD2_k127_885861_0 Aminotransferase class-V K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 414.0
HFD2_k127_885861_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 334.0
HFD2_k127_885861_2 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005143 245.0
HFD2_k127_885861_3 - - - - 0.000000000000000000000000000000000000000000000000000000001339 206.0
HFD2_k127_885861_4 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.000000000000000000000000000000000000000000001674 168.0
HFD2_k127_924822_0 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 571.0
HFD2_k127_924822_1 Histidine-specific methyltransferase, SAM-dependent - - - 0.0000000000000000000000000000000000000000000000000000033 196.0
HFD2_k127_924822_2 Fe-S metabolism associated domain K02426 - - 0.0000000000000000000000000005089 132.0
HFD2_k127_926206_0 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 5.216e-222 702.0
HFD2_k127_926206_1 - - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 650.0
HFD2_k127_926206_10 S23 ribosomal protein - - - 0.000000000000000000000000000000008589 132.0
HFD2_k127_926206_11 Helix-hairpin-helix motif K02237 - - 0.0000000000004753 78.0
HFD2_k127_926206_12 Helix-hairpin-helix motif K02237 - - 0.0000000000006422 78.0
HFD2_k127_926206_2 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 544.0
HFD2_k127_926206_3 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000947 524.0
HFD2_k127_926206_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 313.0
HFD2_k127_926206_5 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 316.0
HFD2_k127_926206_6 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000003387 239.0
HFD2_k127_926206_7 Peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000000000002974 230.0
HFD2_k127_926206_8 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000006576 183.0
HFD2_k127_926206_9 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000005128 170.0
HFD2_k127_932150_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 387.0
HFD2_k127_932150_1 - - - - 0.000000000001534 76.0
HFD2_k127_948146_0 Glucodextranase, domain N K01178 - 3.2.1.3 2.919e-296 927.0
HFD2_k127_948146_1 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 5.429e-218 706.0
HFD2_k127_948146_2 Short-chain dehydrogenase reductase Sdr K00034,K00059,K03366 - 1.1.1.100,1.1.1.304,1.1.1.47,1.1.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008797 330.0
HFD2_k127_948146_3 short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007095 267.0
HFD2_k127_948146_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000002229 215.0
HFD2_k127_948146_5 - - - - 0.000000000000000000000000000002481 133.0
HFD2_k127_948146_6 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000000008483 74.0
HFD2_k127_957007_0 Asparagine synthase - - - 4.683e-196 625.0
HFD2_k127_957007_1 transferase activity, transferring glycosyl groups K13003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 330.0
HFD2_k127_957007_3 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000756 173.0
HFD2_k127_960695_0 Carboxypeptidase regulatory-like domain - - - 8.604e-236 776.0
HFD2_k127_960695_1 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 308.0
HFD2_k127_960695_2 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000002128 153.0
HFD2_k127_960695_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000008984 57.0
HFD2_k127_960782_0 TonB dependent receptor - - - 1.926e-317 1008.0
HFD2_k127_960782_1 Belongs to the glycosyl hydrolase 31 family K01187,K01811 - 3.2.1.177,3.2.1.20 2.23e-282 891.0
HFD2_k127_960782_10 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003122 287.0
HFD2_k127_960782_11 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000001643 214.0
HFD2_k127_960782_12 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000003468 201.0
HFD2_k127_960782_13 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000002318 207.0
HFD2_k127_960782_14 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000006317 176.0
HFD2_k127_960782_15 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000006017 156.0
HFD2_k127_960782_16 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000001086 144.0
HFD2_k127_960782_17 Periplasmic component of the Tol biopolymer transport system - - - 0.0000000000001147 75.0
HFD2_k127_960782_18 BON domain - - - 0.0002371 51.0
HFD2_k127_960782_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.043e-262 820.0
HFD2_k127_960782_3 - - - - 9.264e-239 756.0
HFD2_k127_960782_4 COG0457 FOG TPR repeat - - - 1.905e-199 636.0
HFD2_k127_960782_5 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840 - 5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 536.0
HFD2_k127_960782_6 Cys Met metabolism K01739,K01758 - 2.5.1.48,4.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007599 460.0
HFD2_k127_960782_7 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 420.0
HFD2_k127_960782_8 epimerase K00329,K00356,K00491,K21572 - 1.14.14.47,1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007043 421.0
HFD2_k127_960782_9 GIY-YIG type nucleases (URI domain) K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008139 411.0
HFD2_k127_973699_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007798 356.0
HFD2_k127_973699_1 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000001796 205.0
HFD2_k127_973699_2 aminopeptidase N - - - 0.0000000000000000000000000000000000000000004435 177.0