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Overview

ID MAG01642
Name HFD2_bin.30
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Actinomycetota
Class Acidimicrobiia
Order Acidimicrobiales
Family Ilumatobacteraceae
Genus JAENVT01
Species
Assembly information
Completeness (%) 91.86
Contamination (%) 2.05
GC content (%) 67.0
N50 (bp) 35,851
Genome size (bp) 4,066,849

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3659

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_105466_0 C-terminal, D2-small domain, of ClpB protein K03695 - - 0.0 1328.0
HFD2_k127_105466_1 Heat shock 70 kDa protein K04043 - - 0.0 1027.0
HFD2_k127_105466_10 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 398.0
HFD2_k127_105466_11 DNA segregation ATPase FtsK SpoIIIE and related K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 417.0
HFD2_k127_105466_12 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008976 381.0
HFD2_k127_105466_13 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 344.0
HFD2_k127_105466_14 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 334.0
HFD2_k127_105466_15 Thioesterase-like superfamily K10805 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008522 312.0
HFD2_k127_105466_16 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 308.0
HFD2_k127_105466_17 Two component transcriptional regulator, winged helix family K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 290.0
HFD2_k127_105466_18 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000852 299.0
HFD2_k127_105466_19 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001122 277.0
HFD2_k127_105466_2 Dehydrogenase E1 component K11381 - 1.2.4.4 8.433e-271 848.0
HFD2_k127_105466_20 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000001834 245.0
HFD2_k127_105466_21 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000001942 240.0
HFD2_k127_105466_22 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000269 224.0
HFD2_k127_105466_23 - - - - 0.00000000000000000000000000000000000000000000000003534 190.0
HFD2_k127_105466_24 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000205 174.0
HFD2_k127_105466_25 Flavodoxin reductases ferredoxin-NADPH reductases family 1 - - - 0.0000000000000000000000000000000000000000009096 169.0
HFD2_k127_105466_26 helix_turn_helix, mercury resistance K13640 - - 0.00000000000000000000000000000000000466 154.0
HFD2_k127_105466_27 - - - - 0.00000000000000000000000000000000006321 137.0
HFD2_k127_105466_28 - - - - 0.0000000000000000000000000000002438 133.0
HFD2_k127_105466_3 Peptidase family M41 - - - 2.605e-214 682.0
HFD2_k127_105466_30 RF-1 domain K15034 - - 0.000000000000003607 81.0
HFD2_k127_105466_31 SWIM zinc finger - - - 0.0000000002899 73.0
HFD2_k127_105466_32 F420-dependent oxidoreductase K04091 - 1.14.14.5 0.000000237 53.0
HFD2_k127_105466_4 protein secretion K20276,K21449 - - 5.443e-209 706.0
HFD2_k127_105466_5 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 1.811e-196 630.0
HFD2_k127_105466_6 Non-specific serine threonine protein kinase K08282 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 619.0
HFD2_k127_105466_7 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 578.0
HFD2_k127_105466_8 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 571.0
HFD2_k127_105466_9 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 457.0
HFD2_k127_1062349_0 assembly protein SufB K09014 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - 9.241e-283 892.0
HFD2_k127_1062349_1 Oligopeptidase b K01354 - 3.4.21.83 9.559e-207 665.0
HFD2_k127_1062349_10 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000000000000000000000000000000000000006854 214.0
HFD2_k127_1062349_11 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000000000000000006985 215.0
HFD2_k127_1062349_12 FeS assembly protein SufD K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0040007,GO:0043207,GO:0044085,GO:0044237,GO:0044403,GO:0044419,GO:0050896,GO:0051186,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071840,GO:0075136 - 0.000000000000000000000000000000000000000000000000000001595 205.0
HFD2_k127_1062349_14 PIN domain K07064 - - 0.000000000000000000000000000000000000000007428 163.0
HFD2_k127_1062349_15 - - - - 0.0000000000000000000000000000000000000008231 152.0
HFD2_k127_1062349_16 Family of unknown function (DUF5317) - - - 0.000000000000000000000000000000000000001892 153.0
HFD2_k127_1062349_17 electron transfer activity K05337 GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - 0.0000000000000000000000000000004666 128.0
HFD2_k127_1062349_18 Rieske-like [2Fe-2S] domain K05710 - - 0.0000000000000000000000000006985 116.0
HFD2_k127_1062349_19 Beta-lactamase superfamily domain - - - 0.0000000000000000000000004388 106.0
HFD2_k127_1062349_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 624.0
HFD2_k127_1062349_20 Methylamine utilisation protein MauE - - - 0.00000000000000000000001291 104.0
HFD2_k127_1062349_21 positive regulation of growth - - - 0.0000000000000003735 81.0
HFD2_k127_1062349_3 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005403 561.0
HFD2_k127_1062349_4 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005674 377.0
HFD2_k127_1062349_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 338.0
HFD2_k127_1062349_6 unsaturated fatty acid biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007835 331.0
HFD2_k127_1062349_7 FeS assembly ATPase SufC K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 304.0
HFD2_k127_1062349_8 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003828 278.0
HFD2_k127_1062349_9 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005238 252.0
HFD2_k127_1065508_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.4.1.1 3.467e-301 950.0
HFD2_k127_1065508_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18 6.303e-282 887.0
HFD2_k127_1065508_10 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 585.0
HFD2_k127_1065508_11 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 569.0
HFD2_k127_1065508_12 Major facilitator Superfamily K08369 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008342 536.0
HFD2_k127_1065508_13 Aminotransferase class-V K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 481.0
HFD2_k127_1065508_14 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009029 470.0
HFD2_k127_1065508_15 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 468.0
HFD2_k127_1065508_16 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 464.0
HFD2_k127_1065508_17 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 460.0
HFD2_k127_1065508_18 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 477.0
HFD2_k127_1065508_19 Ammonium Transporter Family K03320 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 461.0
HFD2_k127_1065508_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 5.368e-277 858.0
HFD2_k127_1065508_20 tRNA methyl transferase K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 451.0
HFD2_k127_1065508_21 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 447.0
HFD2_k127_1065508_22 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 460.0
HFD2_k127_1065508_23 PFAM Glycosyl transferase, group 1 K16150 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 433.0
HFD2_k127_1065508_24 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009234 428.0
HFD2_k127_1065508_25 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008825 435.0
HFD2_k127_1065508_26 nucleoside hydrolase K01239,K01250,K10213 - 3.2.2.1,3.2.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 387.0
HFD2_k127_1065508_27 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 350.0
HFD2_k127_1065508_28 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 343.0
HFD2_k127_1065508_29 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 336.0
HFD2_k127_1065508_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.412e-258 802.0
HFD2_k127_1065508_30 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 317.0
HFD2_k127_1065508_31 Methyltransferase small domain K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007723 324.0
HFD2_k127_1065508_32 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006641 318.0
HFD2_k127_1065508_33 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 293.0
HFD2_k127_1065508_34 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008608 254.0
HFD2_k127_1065508_35 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000002971 237.0
HFD2_k127_1065508_36 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001487 241.0
HFD2_k127_1065508_37 - - - - 0.0000000000000000000000000000000000000000000000000000000000000013 231.0
HFD2_k127_1065508_38 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000006726 206.0
HFD2_k127_1065508_39 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000006971 201.0
HFD2_k127_1065508_4 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.437e-253 799.0
HFD2_k127_1065508_40 - - - - 0.00000000000000000000000000000000000000000000000000008823 197.0
HFD2_k127_1065508_41 Sterol carrier protein - - - 0.000000000000000000000000000000000000000000000000000723 186.0
HFD2_k127_1065508_42 Hydrolase of the alpha beta-hydrolase K07020 - - 0.000000000000000000000000000000000000000000000000002892 187.0
HFD2_k127_1065508_43 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000003564 180.0
HFD2_k127_1065508_44 - - - - 0.0000000000000000000000000000000000000000000000004615 180.0
HFD2_k127_1065508_45 AzlC protein - - - 0.000000000000000000000000000000000000000000004984 179.0
HFD2_k127_1065508_46 Belongs to the P(II) protein family K04751 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000001048 160.0
HFD2_k127_1065508_47 - - - - 0.0000000000000000000000000000000000000009322 160.0
HFD2_k127_1065508_48 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000004273 156.0
HFD2_k127_1065508_49 proton-transporting ATP synthase activity, rotational mechanism K02114 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000001638 148.0
HFD2_k127_1065508_5 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 2.629e-234 737.0
HFD2_k127_1065508_50 Flavodoxin reductases ferredoxin-NADPH reductases family 1 - - - 0.000000000000000000000000000000000175 144.0
HFD2_k127_1065508_52 ATP synthesis coupled proton transport K02109 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.000000000000000000000000000000003687 135.0
HFD2_k127_1065508_53 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000002971 127.0
HFD2_k127_1065508_54 NifU-like domain - - - 0.0000000000000000000000000225 116.0
HFD2_k127_1065508_55 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000001962 119.0
HFD2_k127_1065508_59 Branched-chain amino acid transport protein (AzlD) - - - 0.000000002631 69.0
HFD2_k127_1065508_6 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 1.08e-229 730.0
HFD2_k127_1065508_7 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.433e-213 676.0
HFD2_k127_1065508_8 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 600.0
HFD2_k127_1065508_9 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 586.0
HFD2_k127_1072996_0 Acetyl-CoA carboxylase, central region - - - 0.0 1257.0
HFD2_k127_1072996_1 Ketoacyl-synthetase C-terminal extension - - - 5.909e-285 902.0
HFD2_k127_1076827_0 von Willebrand factor (vWF) type A domain - - - 1.794e-319 989.0
HFD2_k127_1076827_1 Mg-chelatase subunit ChlI K03405 - 6.6.1.1 4.642e-234 731.0
HFD2_k127_1076827_2 Belongs to the xylose isomerase family K01805 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 587.0
HFD2_k127_1076827_3 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005813 274.0
HFD2_k127_1076827_4 beta-mannosidase K01192,K15855 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005576,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044238,GO:0071704,GO:1901575 3.2.1.165,3.2.1.25 0.0000000000000000000000000000000000000000000000001646 181.0
HFD2_k127_1076827_5 beta-glucosidase activity K00067,K05350 - 1.1.1.133,3.2.1.21 0.0000000000000000000000000000001214 136.0
HFD2_k127_1076827_8 Sigma-70, region 4 - - - 0.000000000000005526 79.0
HFD2_k127_1076827_9 - - - - 0.0000000001038 65.0
HFD2_k127_1141201_0 4Fe-4S dicluster domain - - - 0.0 1197.0
HFD2_k127_1141201_1 phosphoglycerate mutase activity K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 303.0
HFD2_k127_1141201_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000007281 181.0
HFD2_k127_1141201_3 Drug exporters of the RND superfamily K06994 - - 0.0000000000000000000000000000000000623 144.0
HFD2_k127_1141201_4 cyclic nucleotide binding K10914 - - 0.000000000000000000000000004632 117.0
HFD2_k127_1141201_5 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00000000000001126 89.0
HFD2_k127_1225412_0 mandelate racemase muconate lactonizing K18334 - 4.2.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 587.0
HFD2_k127_1225412_1 luxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 535.0
HFD2_k127_1225412_10 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000000000002156 188.0
HFD2_k127_1225412_11 Short repeat of unknown function (DUF308) - - - 0.000000000000000000000000000000000000000000000000009497 194.0
HFD2_k127_1225412_12 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000008496 154.0
HFD2_k127_1225412_13 Protein of unknown function (DUF1272) K09984 - - 0.0000000000000000000000696 98.0
HFD2_k127_1225412_14 Diacylglycerol kinase - - - 0.000000000000000000181 98.0
HFD2_k127_1225412_15 - - - - 0.0000000000022 75.0
HFD2_k127_1225412_16 Pfam:DUF1049 - - - 0.0004335 47.0
HFD2_k127_1225412_2 Branched-chain amino acid transport system / permease component K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 409.0
HFD2_k127_1225412_3 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 394.0
HFD2_k127_1225412_4 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 372.0
HFD2_k127_1225412_5 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 344.0
HFD2_k127_1225412_6 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 352.0
HFD2_k127_1225412_7 amidohydrolase K07046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 302.0
HFD2_k127_1225412_8 gntR family K05799 - - 0.00000000000000000000000000000000000000000000000000000000000000000003915 239.0
HFD2_k127_1225412_9 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000005511 209.0
HFD2_k127_125451_0 glycoside hydrolase 15-related K01178 - 3.2.1.3 0.0 1363.0
HFD2_k127_125451_1 Non-essential cell division protein that could be required for efficient cell constriction - - - 1.008e-274 869.0
HFD2_k127_125451_10 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005255 463.0
HFD2_k127_125451_11 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K04127,K11325,K21174 - 5.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 421.0
HFD2_k127_125451_12 Signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 405.0
HFD2_k127_125451_13 Beta propeller domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006827 397.0
HFD2_k127_125451_14 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 353.0
HFD2_k127_125451_15 binding-protein-dependent transport systems inner membrane component K10234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 345.0
HFD2_k127_125451_17 Response regulator receiver K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002744 274.0
HFD2_k127_125451_18 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003942 266.0
HFD2_k127_125451_19 helix_turn _helix lactose operon repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000001373 248.0
HFD2_k127_125451_2 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 1.594e-213 689.0
HFD2_k127_125451_21 MDMPI C-terminal domain - - - 0.000000000000000000000000000000000000000000000000002446 194.0
HFD2_k127_125451_22 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000003229 187.0
HFD2_k127_125451_23 Binding-protein-dependent transport system inner membrane component K10233 - - 0.000000000000000000000000000000000000000000002208 171.0
HFD2_k127_125451_24 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000006248 174.0
HFD2_k127_125451_25 - - - - 0.0000000000000000000000000000000000000007773 153.0
HFD2_k127_125451_26 Tetratricopeptide repeat - - - 0.0000000000000000000000000000005445 138.0
HFD2_k127_125451_27 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000002568 130.0
HFD2_k127_125451_28 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division - GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000002884 109.0
HFD2_k127_125451_29 Nuclease-related domain - - - 0.00000000000000000000007801 105.0
HFD2_k127_125451_3 Alpha-amylase domain K01187 - 3.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000985 604.0
HFD2_k127_125451_30 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000002037 113.0
HFD2_k127_125451_31 Nuclease-related domain - - - 0.00008495 50.0
HFD2_k127_125451_4 PFAM ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 572.0
HFD2_k127_125451_5 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 547.0
HFD2_k127_125451_6 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 516.0
HFD2_k127_125451_7 PFAM zinc finger SWIM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 531.0
HFD2_k127_125451_8 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 500.0
HFD2_k127_125451_9 VWA containing CoxE family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 473.0
HFD2_k127_1295507_0 AAA domain K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 455.0
HFD2_k127_1295507_1 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 401.0
HFD2_k127_1295507_10 alpha/beta hydrolase fold K08680 - 4.2.99.20 0.000000000000000000000000000000000000000000000000000000000003585 221.0
HFD2_k127_1295507_11 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000000000000001124 188.0
HFD2_k127_1295507_2 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain K21023 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 384.0
HFD2_k127_1295507_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 349.0
HFD2_k127_1295507_4 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007909 316.0
HFD2_k127_1295507_5 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 319.0
HFD2_k127_1295507_6 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000002888 282.0
HFD2_k127_1295507_7 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001115 273.0
HFD2_k127_1295507_8 Dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000003606 246.0
HFD2_k127_1295507_9 elongation factor Tu domain 2 protein K02355 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000476 216.0
HFD2_k127_1328455_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.023e-244 783.0
HFD2_k127_1328455_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.558e-236 741.0
HFD2_k127_1328455_10 peptidase K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 421.0
HFD2_k127_1328455_11 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 344.0
HFD2_k127_1328455_12 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 341.0
HFD2_k127_1328455_13 Helix-turn-helix domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 331.0
HFD2_k127_1328455_14 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 314.0
HFD2_k127_1328455_15 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005989 301.0
HFD2_k127_1328455_16 neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002535 289.0
HFD2_k127_1328455_17 RarD protein K05786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004132 276.0
HFD2_k127_1328455_18 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000001471 206.0
HFD2_k127_1328455_19 Phosphoglucose isomerase K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000009788 186.0
HFD2_k127_1328455_2 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 7.695e-230 717.0
HFD2_k127_1328455_20 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000002203 177.0
HFD2_k127_1328455_21 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000003035 166.0
HFD2_k127_1328455_22 Domain of unknown function (DUF4202) - - - 0.0000000000000000000000000000000000000756 153.0
HFD2_k127_1328455_23 Phosphotransferase enzyme family K18817 - 2.7.1.163 0.0000000000000000000000000000000000003827 152.0
HFD2_k127_1328455_24 Domain of unknown function (DUF305) - - - 0.00000000000000000000000000007291 125.0
HFD2_k127_1328455_25 Methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000004659 106.0
HFD2_k127_1328455_26 FR47-like protein - - - 0.000000000000000000001212 101.0
HFD2_k127_1328455_28 - - - - 0.0000000000000007675 88.0
HFD2_k127_1328455_29 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000008757 61.0
HFD2_k127_1328455_3 Belongs to the GPI family K01810 GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 9.733e-214 676.0
HFD2_k127_1328455_30 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0004005 46.0
HFD2_k127_1328455_4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 GO:0000271,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901576 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 592.0
HFD2_k127_1328455_5 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 584.0
HFD2_k127_1328455_6 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 474.0
HFD2_k127_1328455_7 Ppx GppA phosphatase K01524 GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 458.0
HFD2_k127_1328455_8 Nitrite and sulphite reductase 4Fe-4S domain K00362,K00366,K00381,K00392 - 1.7.1.15,1.7.7.1,1.8.1.2,1.8.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 450.0
HFD2_k127_1328455_9 peptidase activity, acting on L-amino acid peptides K01337,K01400,K20276 - 3.4.21.50,3.4.24.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 447.0
HFD2_k127_139615_0 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 469.0
HFD2_k127_139615_1 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 436.0
HFD2_k127_139615_10 Colicin V production protein - - - 0.000000000000000000000000000002308 133.0
HFD2_k127_139615_11 Colicin V production protein - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009268,GO:0009405,GO:0009628,GO:0010447,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051704,GO:0071944 - 0.000000000000000001378 94.0
HFD2_k127_139615_2 Extradiol ring-cleavage dioxygenase class III protein subunit B K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 380.0
HFD2_k127_139615_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 367.0
HFD2_k127_139615_4 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000156 247.0
HFD2_k127_139615_5 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000001395 190.0
HFD2_k127_139615_6 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000006929 185.0
HFD2_k127_139615_7 Rieske-like [2Fe-2S] domain K05710,K14578,K18248 - - 0.000000000000000000000000000000000000000006782 155.0
HFD2_k127_139615_8 protein histidine kinase activity - - - 0.00000000000000000000000000000000000001782 158.0
HFD2_k127_139615_9 COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs K03519 - 1.2.5.3 0.00000000000000000000000000000000001358 152.0
HFD2_k127_1396562_0 UDP binding domain K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 548.0
HFD2_k127_1396562_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 419.0
HFD2_k127_1396562_2 3-beta hydroxysteroid dehydrogenase/isomerase family K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 387.0
HFD2_k127_1396562_3 thiolester hydrolase activity K01990,K06889 GO:0008150,GO:0009987,GO:0051301 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 352.0
HFD2_k127_1396562_4 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001292 244.0
HFD2_k127_1396562_5 MDMPI C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000003205 204.0
HFD2_k127_1396562_6 - - - - 0.00000000000000000000000000000000000000000000000000005541 190.0
HFD2_k127_1396562_7 CHRD domain - - - 0.0000000000002306 78.0
HFD2_k127_1427453_0 ABC transporter transmembrane region K06147 - - 2.577e-243 793.0
HFD2_k127_1427453_1 ABC transporter transmembrane region K06147 - - 6.725e-242 760.0
HFD2_k127_1427453_10 dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000000000000000000000000000000000006537 237.0
HFD2_k127_1427453_11 molybdenum ion binding K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000002487 233.0
HFD2_k127_1427453_12 penicillin-binding protein - - - 0.0000000000000000000000000000000000000000000000000000005715 202.0
HFD2_k127_1427453_13 alpha-ribazole phosphatase activity K02226,K15634,K22305,K22306,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.3,3.1.3.73,3.1.3.85,5.4.2.12 0.00000000000000000000000000000000000000000000000000478 186.0
HFD2_k127_1427453_14 arsR family - - - 0.00000000000000000000000000000000000000000005894 164.0
HFD2_k127_1427453_15 transcriptional regulator - - - 0.0000000000000000000000000000000000000000002273 165.0
HFD2_k127_1427453_16 - - - - 0.0000000000000000000000000000000000000000008985 161.0
HFD2_k127_1427453_17 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000371 161.0
HFD2_k127_1427453_18 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000005559 152.0
HFD2_k127_1427453_19 - - - - 0.00000000000000000000000000000000007136 138.0
HFD2_k127_1427453_2 penicillin-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 550.0
HFD2_k127_1427453_20 - K07164,K22391 - 3.5.4.16 0.0000000000000000000000002098 114.0
HFD2_k127_1427453_21 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000006187 100.0
HFD2_k127_1427453_22 Protein of unknown function (DUF1326) - - - 0.000000000000000003374 93.0
HFD2_k127_1427453_23 STAS domain K06378 - - 0.000000000006848 71.0
HFD2_k127_1427453_24 STAS domain K04749 - - 0.0000000002237 65.0
HFD2_k127_1427453_25 STAS domain - - - 0.0009721 46.0
HFD2_k127_1427453_3 involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 471.0
HFD2_k127_1427453_4 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006469 436.0
HFD2_k127_1427453_5 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 398.0
HFD2_k127_1427453_6 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007611 385.0
HFD2_k127_1427453_7 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009799 287.0
HFD2_k127_1427453_8 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005234 283.0
HFD2_k127_1427453_9 Activator of Hsp90 ATPase 1 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006275 247.0
HFD2_k127_1544539_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1281.0
HFD2_k127_1544539_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 6.589e-272 846.0
HFD2_k127_1544539_10 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 365.0
HFD2_k127_1544539_11 response regulator, receiver K02483,K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 312.0
HFD2_k127_1544539_12 Ferric reductase like transmembrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000001467 245.0
HFD2_k127_1544539_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001372 225.0
HFD2_k127_1544539_14 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000005707 217.0
HFD2_k127_1544539_15 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000002668 208.0
HFD2_k127_1544539_16 protein conserved in bacteria K09966 - - 0.00000000000000000000000000000000000000000000000000003347 194.0
HFD2_k127_1544539_17 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000005036 188.0
HFD2_k127_1544539_18 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000021 184.0
HFD2_k127_1544539_19 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000002151 192.0
HFD2_k127_1544539_2 4-hydroxyphenylacetate 3-hydroxylase N terminal K00483,K21726 - 1.14.13.166,1.14.13.29,1.14.14.9 6.644e-234 751.0
HFD2_k127_1544539_20 DUF218 domain - - - 0.000000000000000000000000000000000000000722 163.0
HFD2_k127_1544539_21 Poly(3-hydroxybutyrate) depolymerase K03932 - - 0.000000000000000000000000000000000000003488 161.0
HFD2_k127_1544539_22 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000001698 128.0
HFD2_k127_1544539_23 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000003366 117.0
HFD2_k127_1544539_24 Flavin reductase like domain K16048 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006066,GO:0006629,GO:0006694,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008610,GO:0009056,GO:0009058,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016645,GO:0016646,GO:0036094,GO:0042602,GO:0043167,GO:0043168,GO:0044238,GO:0044281,GO:0044282,GO:0046164,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1902652 - 0.00000000000000000025 96.0
HFD2_k127_1544539_25 FMN_bind - - - 0.00000000000000002302 92.0
HFD2_k127_1544539_26 ABC-type transport system, involved in lipoprotein release, permease component K02004 - - 0.0000000006006 73.0
HFD2_k127_1544539_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 6.178e-201 635.0
HFD2_k127_1544539_4 Histidine kinase K07646 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 2.7.13.3 3.694e-195 639.0
HFD2_k127_1544539_5 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 608.0
HFD2_k127_1544539_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 521.0
HFD2_k127_1544539_7 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 515.0
HFD2_k127_1544539_8 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000716 510.0
HFD2_k127_1544539_9 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 494.0
HFD2_k127_1798546_0 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.0 1626.0
HFD2_k127_1798546_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 8.022e-286 885.0
HFD2_k127_1798546_10 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 320.0
HFD2_k127_1798546_11 ABC 3 transport family K09816,K09819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 314.0
HFD2_k127_1798546_12 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001237 296.0
HFD2_k127_1798546_13 Zinc-uptake complex component A periplasmic K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004821 269.0
HFD2_k127_1798546_14 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001159 259.0
HFD2_k127_1798546_15 Belongs to the GcvT family K00302 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000002277 270.0
HFD2_k127_1798546_16 ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000001738 256.0
HFD2_k127_1798546_17 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000008519 213.0
HFD2_k127_1798546_18 endonuclease activity - - - 0.00000000000000000000000000000000000000000000000000000002069 213.0
HFD2_k127_1798546_19 transcriptional regulator - - - 0.000000000000000000000000000000000000000007987 163.0
HFD2_k127_1798546_2 NADH:flavin oxidoreductase / NADH oxidase family K00219,K21833 - 1.3.1.34 6.463e-281 877.0
HFD2_k127_1798546_20 Ferric uptake regulator family K03711 - - 0.0000000000000000000000000000000000005347 144.0
HFD2_k127_1798546_21 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000003004 128.0
HFD2_k127_1798546_22 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000002802 115.0
HFD2_k127_1798546_23 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000003977 122.0
HFD2_k127_1798546_24 Sarcosine oxidase, delta subunit family K00304 - 1.5.3.1 0.00000000005505 75.0
HFD2_k127_1798546_3 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 5.39e-279 888.0
HFD2_k127_1798546_4 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 3.085e-277 861.0
HFD2_k127_1798546_5 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 2.261e-213 675.0
HFD2_k127_1798546_6 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 574.0
HFD2_k127_1798546_7 dipeptide transport K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 443.0
HFD2_k127_1798546_8 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 406.0
HFD2_k127_1798546_9 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 373.0
HFD2_k127_1821279_0 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 608.0
HFD2_k127_1821279_1 phosphoribosyltransferase K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 518.0
HFD2_k127_1821279_10 Pfam Cation efflux - - - 0.0000000000000000000000000000000000000000000000000004675 194.0
HFD2_k127_1821279_11 - - - - 0.00000000000000000000000000000000000000000000000001161 187.0
HFD2_k127_1821279_12 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000002049 152.0
HFD2_k127_1821279_13 coenzyme F420 binding - - - 0.000000000000000000000000000000002129 139.0
HFD2_k127_1821279_14 Transcriptional regulator, arsR family - - - 0.00000000000003222 78.0
HFD2_k127_1821279_15 KR domain - - - 0.000000000000281 73.0
HFD2_k127_1821279_2 Winged helix DNA-binding domain K09927 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 505.0
HFD2_k127_1821279_3 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 475.0
HFD2_k127_1821279_4 Mo-co oxidoreductase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 413.0
HFD2_k127_1821279_6 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 320.0
HFD2_k127_1821279_7 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000368 284.0
HFD2_k127_1821279_8 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002544 240.0
HFD2_k127_1821279_9 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000002127 233.0
HFD2_k127_1854389_0 Acyl transferase domain - - - 0.0 1173.0
HFD2_k127_1854389_1 Aconitase family (aconitate hydratase) K01681 - 4.2.1.3 0.0 1168.0
HFD2_k127_1854389_10 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 512.0
HFD2_k127_1854389_11 Oxidoreductase molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 466.0
HFD2_k127_1854389_12 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 445.0
HFD2_k127_1854389_13 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 372.0
HFD2_k127_1854389_14 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 360.0
HFD2_k127_1854389_15 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 362.0
HFD2_k127_1854389_16 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 346.0
HFD2_k127_1854389_17 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 323.0
HFD2_k127_1854389_18 PFAM Fatty acid desaturase, type 2 K03921 - 1.14.19.11,1.14.19.2,1.14.19.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 313.0
HFD2_k127_1854389_19 ABC transporter, ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007318 309.0
HFD2_k127_1854389_2 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 2.772e-271 854.0
HFD2_k127_1854389_20 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 299.0
HFD2_k127_1854389_21 UTRA K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 292.0
HFD2_k127_1854389_22 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003315 278.0
HFD2_k127_1854389_23 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007266 271.0
HFD2_k127_1854389_24 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002778 251.0
HFD2_k127_1854389_25 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000004029 235.0
HFD2_k127_1854389_26 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000001848 216.0
HFD2_k127_1854389_27 2-hydroxy-3-oxopropionate reductase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000354 203.0
HFD2_k127_1854389_28 Cytochrome oxidase assembly protein K02259 - - 0.0000000000000000000000000000000000000000000000000002324 195.0
HFD2_k127_1854389_29 transglycosylase - - - 0.000000000000000000000000000000000000000000000002123 186.0
HFD2_k127_1854389_3 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 1.234e-232 727.0
HFD2_k127_1854389_30 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000003449 180.0
HFD2_k127_1854389_31 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000004771 176.0
HFD2_k127_1854389_32 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000000000005645 174.0
HFD2_k127_1854389_33 BetI-type transcriptional repressor, C-terminal - - - 0.00000000000000000000000000000000000000000024 171.0
HFD2_k127_1854389_34 Bacterial regulatory proteins, tetR family K18939 - - 0.000000000000000000000000000000000000003656 154.0
HFD2_k127_1854389_35 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.000000000000000000000000000000001096 139.0
HFD2_k127_1854389_36 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000006462 118.0
HFD2_k127_1854389_37 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000002099 94.0
HFD2_k127_1854389_38 SnoaL-like domain - - - 0.00000005568 64.0
HFD2_k127_1854389_39 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.0000008686 56.0
HFD2_k127_1854389_4 acyl-CoA dehydrogenase activity - - - 1.245e-228 724.0
HFD2_k127_1854389_5 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 1.315e-219 687.0
HFD2_k127_1854389_6 HAD-superfamily subfamily IB hydrolase, TIGR01490 K15781 - 2.3.1.51,3.1.3.3 9.015e-198 627.0
HFD2_k127_1854389_7 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 608.0
HFD2_k127_1854389_8 Carboxyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 609.0
HFD2_k127_1854389_9 Alkyl sulfatase dimerisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 549.0
HFD2_k127_1864889_0 Salmonella virulence plasmid 65kDa B protein - - - 0.0 1539.0
HFD2_k127_1864889_1 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 378.0
HFD2_k127_1864889_10 Bacterial extracellular solute-binding protein K10232 - - 0.0000000000000000000000000000000000001694 165.0
HFD2_k127_1864889_11 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.00000000000000000000000000000000000196 162.0
HFD2_k127_1864889_12 AAA ATPase domain - - - 0.00000000000000000000002478 106.0
HFD2_k127_1864889_13 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01179,K01637 - 3.2.1.4,4.1.3.1 0.00000000000000000000002723 118.0
HFD2_k127_1864889_14 TatD related DNase K03424 - - 0.000000000000001725 85.0
HFD2_k127_1864889_15 peptidase M36 K01417 - - 0.00000001731 69.0
HFD2_k127_1864889_16 transcription factor binding - - - 0.0000003413 53.0
HFD2_k127_1864889_17 membrane protein (DUF2078) K08982 - - 0.00001138 54.0
HFD2_k127_1864889_18 Bacterial protein of unknown function (DUF899) - - - 0.00003714 49.0
HFD2_k127_1864889_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 414.0
HFD2_k127_1864889_3 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001315 272.0
HFD2_k127_1864889_4 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006763 257.0
HFD2_k127_1864889_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007434 268.0
HFD2_k127_1864889_6 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000005233 241.0
HFD2_k127_1864889_7 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000000000001998 210.0
HFD2_k127_1864889_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000002106 190.0
HFD2_k127_1864889_9 Acid phosphatase homologues K06153,K19302 - 3.6.1.27 0.000000000000000000000000000000000000000001337 163.0
HFD2_k127_1866413_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1101.0
HFD2_k127_1866413_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 7.906e-313 970.0
HFD2_k127_1866413_10 DSHCT K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 3.751e-237 763.0
HFD2_k127_1866413_11 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 2.2e-232 745.0
HFD2_k127_1866413_12 MgsA AAA+ ATPase C terminal K07478 - - 2.577e-210 661.0
HFD2_k127_1866413_13 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 1.4e-201 638.0
HFD2_k127_1866413_14 Amino acid permease - - - 2.988e-194 632.0
HFD2_k127_1866413_15 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 607.0
HFD2_k127_1866413_16 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 579.0
HFD2_k127_1866413_17 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 520.0
HFD2_k127_1866413_18 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 517.0
HFD2_k127_1866413_19 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 506.0
HFD2_k127_1866413_2 CoA binding domain - - - 6.582e-312 975.0
HFD2_k127_1866413_20 4Fe-4S dicluster domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007477 500.0
HFD2_k127_1866413_21 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 468.0
HFD2_k127_1866413_22 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 430.0
HFD2_k127_1866413_23 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 413.0
HFD2_k127_1866413_24 cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 421.0
HFD2_k127_1866413_25 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 416.0
HFD2_k127_1866413_26 Glycosyl transferases group 1 K08256 - 2.4.1.345 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006706 415.0
HFD2_k127_1866413_27 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 379.0
HFD2_k127_1866413_28 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 379.0
HFD2_k127_1866413_29 Peptidase, M20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 377.0
HFD2_k127_1866413_3 Proteasomal ATPase OB/ID domain K13527 - - 6.553e-302 932.0
HFD2_k127_1866413_30 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 379.0
HFD2_k127_1866413_31 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 344.0
HFD2_k127_1866413_32 Amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 342.0
HFD2_k127_1866413_33 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 329.0
HFD2_k127_1866413_34 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 344.0
HFD2_k127_1866413_35 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 325.0
HFD2_k127_1866413_36 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 324.0
HFD2_k127_1866413_37 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 340.0
HFD2_k127_1866413_38 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 319.0
HFD2_k127_1866413_39 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 301.0
HFD2_k127_1866413_4 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 1.407e-279 872.0
HFD2_k127_1866413_40 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 297.0
HFD2_k127_1866413_41 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 296.0
HFD2_k127_1866413_42 allophanate hydrolase subunit 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000437 292.0
HFD2_k127_1866413_43 transcriptional regulator K09017 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001685 285.0
HFD2_k127_1866413_44 Belongs to the FPG family K05522 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005214 283.0
HFD2_k127_1866413_45 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003456 278.0
HFD2_k127_1866413_46 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001495 278.0
HFD2_k127_1866413_47 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004489 273.0
HFD2_k127_1866413_48 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001129 267.0
HFD2_k127_1866413_49 homoserine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002597 269.0
HFD2_k127_1866413_5 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 - 6.3.1.19 4.723e-273 851.0
HFD2_k127_1866413_50 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001048 260.0
HFD2_k127_1866413_51 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000004125 248.0
HFD2_k127_1866413_52 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007415 243.0
HFD2_k127_1866413_53 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000004918 232.0
HFD2_k127_1866413_54 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000008521 246.0
HFD2_k127_1866413_55 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000000004084 229.0
HFD2_k127_1866413_56 NUDIX hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000946 229.0
HFD2_k127_1866413_57 Protein of unknown function (DUF3048) C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005214 239.0
HFD2_k127_1866413_58 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000007517 229.0
HFD2_k127_1866413_6 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 7.083e-266 830.0
HFD2_k127_1866413_60 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000007495 217.0
HFD2_k127_1866413_61 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000001495 219.0
HFD2_k127_1866413_62 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000003037 226.0
HFD2_k127_1866413_63 peptidase activity K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000004522 228.0
HFD2_k127_1866413_64 Peptidase S16, lon domain protein K01338,K07157 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000006055 196.0
HFD2_k127_1866413_65 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000000000000000000002998 198.0
HFD2_k127_1866413_66 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000008263 186.0
HFD2_k127_1866413_67 Protein of unknown function (DUF3048) C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000704 192.0
HFD2_k127_1866413_68 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000005879 177.0
HFD2_k127_1866413_69 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000005987 177.0
HFD2_k127_1866413_7 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 2.205e-265 826.0
HFD2_k127_1866413_70 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 0.000000000000000000000000000000000000000000000006465 179.0
HFD2_k127_1866413_71 nUDIX hydrolase K08311 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010468,GO:0010604,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0033554,GO:0034353,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0043487,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0045935,GO:0046483,GO:0046700,GO:0046872,GO:0048518,GO:0048519,GO:0048522,GO:0050779,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000001786 172.0
HFD2_k127_1866413_72 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000005077 187.0
HFD2_k127_1866413_73 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.0000000000000000000000000000000000000000001015 173.0
HFD2_k127_1866413_74 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.00000000000000000000000000000000000000001055 154.0
HFD2_k127_1866413_76 Pyridoxal-dependent decarboxylase conserved domain K01634 - 4.1.2.27 0.0000000000000000000000000000000000001486 146.0
HFD2_k127_1866413_78 lipid kinase activity - - - 0.00000000000000000000000000000000002931 144.0
HFD2_k127_1866413_79 thiolester hydrolase activity K17362 - - 0.0000000000000000000000000000002381 132.0
HFD2_k127_1866413_8 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 7.723e-255 797.0
HFD2_k127_1866413_81 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.000000000000000000000000000004346 129.0
HFD2_k127_1866413_82 - - - - 0.0000000000000000000000000001091 121.0
HFD2_k127_1866413_83 Helix-turn-helix domain, rpiR family - - - 0.0000000000000000000000000001267 126.0
HFD2_k127_1866413_84 protein secretion K03116,K03117 GO:0003674,GO:0005215 - 0.00000000000000000000000742 106.0
HFD2_k127_1866413_85 Preprotein translocase subunit YajC K03210 - - 0.000000000000000000000008015 106.0
HFD2_k127_1866413_86 Acetyltransferase (GNAT) family - - - 0.0000000000000000000001801 107.0
HFD2_k127_1866413_87 - - - - 0.000000000000000000003302 103.0
HFD2_k127_1866413_88 Glyoxalase-like domain - - - 0.000000000000000000007998 93.0
HFD2_k127_1866413_89 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation K13570 - - 0.00000000000000000004538 91.0
HFD2_k127_1866413_9 Pup-ligase protein K20814 - 3.5.1.119 1.423e-242 756.0
HFD2_k127_1866413_90 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.00000000000000000007131 102.0
HFD2_k127_1866413_91 Psort location Cytoplasmic, score - - - 0.0000000000000000001035 100.0
HFD2_k127_1866413_93 - - - - 0.000000000000000001529 89.0
HFD2_k127_1866413_96 - - - - 0.00000000002263 70.0
HFD2_k127_1879192_0 Glutamine amidotransferase domain K00820 - 2.6.1.16 0.0 1398.0
HFD2_k127_1879192_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 526.0
HFD2_k127_1879192_10 tRNA threonylcarbamoyladenosine modification K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 327.0
HFD2_k127_1879192_11 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 295.0
HFD2_k127_1879192_12 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000001175 223.0
HFD2_k127_1879192_13 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000000000003821 212.0
HFD2_k127_1879192_14 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000001749 212.0
HFD2_k127_1879192_15 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000000008223 208.0
HFD2_k127_1879192_16 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000001762 182.0
HFD2_k127_1879192_17 Ribosomal protein S9/S16 K02996 - - 0.00000000000000000000000000000000000000000000000287 177.0
HFD2_k127_1879192_18 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000000000002277 172.0
HFD2_k127_1879192_19 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000005792 172.0
HFD2_k127_1879192_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 522.0
HFD2_k127_1879192_20 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000001093 146.0
HFD2_k127_1879192_21 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.00000000000000000000000000000001412 130.0
HFD2_k127_1879192_22 CYTH - - - 0.000000000000000000000000000003892 124.0
HFD2_k127_1879192_23 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000002069 113.0
HFD2_k127_1879192_25 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000004927 74.0
HFD2_k127_1879192_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 500.0
HFD2_k127_1879192_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 482.0
HFD2_k127_1879192_5 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 403.0
HFD2_k127_1879192_6 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 391.0
HFD2_k127_1879192_7 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 375.0
HFD2_k127_1879192_8 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 361.0
HFD2_k127_1879192_9 PFAM Glycosyl transferases group 1 K03867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 362.0
HFD2_k127_1896352_0 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 526.0
HFD2_k127_1896352_1 Branched-chain amino acid ATP-binding cassette transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007872 318.0
HFD2_k127_1896352_2 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 309.0
HFD2_k127_1896352_3 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 289.0
HFD2_k127_1896352_4 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000002206 243.0
HFD2_k127_1896352_5 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000004837 241.0
HFD2_k127_1896352_6 Phosphoenolpyruvate synthase pyruvate phosphate K01007 - 2.7.9.2 0.00000000002167 76.0
HFD2_k127_1900476_1 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 447.0
HFD2_k127_1900476_10 EVE domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000002582 194.0
HFD2_k127_1900476_11 Precorrin-8x methylmutase - - - 0.00000000000000000000000000000000000000000000000001874 188.0
HFD2_k127_1900476_12 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000005203 174.0
HFD2_k127_1900476_13 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000005017 146.0
HFD2_k127_1900476_14 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K15520 - 2.3.1.189 0.0000000000000000000000000006379 129.0
HFD2_k127_1900476_15 belongs to the sigma-70 factor family, ECF subfamily - - - 0.0000000000000000000000000133 118.0
HFD2_k127_1900476_16 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059,K07124 - 1.1.1.100 0.0000000000000000000000005187 116.0
HFD2_k127_1900476_17 - - - - 0.00000000006862 70.0
HFD2_k127_1900476_18 Phosphatase - - - 0.0000000001327 74.0
HFD2_k127_1900476_19 TIGRFAM Outer membrane protein - - - 0.0000003073 63.0
HFD2_k127_1900476_2 Domain of unknown function (DUF4389) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 429.0
HFD2_k127_1900476_21 DsrE/DsrF-like family - - - 0.000355 46.0
HFD2_k127_1900476_3 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 396.0
HFD2_k127_1900476_4 Belongs to the ATCase OTCase family - GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0019627,GO:0034641,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 334.0
HFD2_k127_1900476_5 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007821 303.0
HFD2_k127_1900476_6 Domain present in PSD-95, Dlg, and ZO-1/2. K08372 - - 0.000000000000000000000000000000000000000000000000000000000000000000001309 258.0
HFD2_k127_1900476_7 Permeases of the drug metabolite transporter DMT superfamily K15269 - - 0.0000000000000000000000000000000000000000000000000000000000000000000146 252.0
HFD2_k127_1900476_8 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000000000000009191 211.0
HFD2_k127_1900476_9 molybdopterin cofactor binding - - - 0.00000000000000000000000000000000000000000000000000000001125 207.0
HFD2_k127_192654_0 Hydroxymethylglutaryl-coenzyme A reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 579.0
HFD2_k127_192654_1 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 421.0
HFD2_k127_192654_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000004765 78.0
HFD2_k127_1981936_0 ATPase P-type (Transporting), HAD superfamily, subfamily IC - - - 0.0 1058.0
HFD2_k127_1981936_1 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 1.774e-213 670.0
HFD2_k127_1981936_10 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 365.0
HFD2_k127_1981936_11 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 361.0
HFD2_k127_1981936_12 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 342.0
HFD2_k127_1981936_13 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 333.0
HFD2_k127_1981936_14 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 292.0
HFD2_k127_1981936_15 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 295.0
HFD2_k127_1981936_16 belongs to the sigma-70 factor family K03090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 288.0
HFD2_k127_1981936_17 Peptidase inhibitor I9 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001472 293.0
HFD2_k127_1981936_18 Choline/ethanolamine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003715 276.0
HFD2_k127_1981936_19 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001022 267.0
HFD2_k127_1981936_2 Belongs to the proline racemase family K01777 - 5.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005494 503.0
HFD2_k127_1981936_20 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004726 258.0
HFD2_k127_1981936_21 CHRD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006166 252.0
HFD2_k127_1981936_22 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001958 239.0
HFD2_k127_1981936_23 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000578 237.0
HFD2_k127_1981936_24 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000003138 239.0
HFD2_k127_1981936_25 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000000000000000000000000000000002269 229.0
HFD2_k127_1981936_26 DNA synthesis involved in DNA repair - - - 0.000000000000000000000000000000000000000000000000000000000000003585 224.0
HFD2_k127_1981936_27 Lysyl oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000004455 225.0
HFD2_k127_1981936_28 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000004666 218.0
HFD2_k127_1981936_29 Domain of unknown function (DUF427) - - - 0.00000000000000000000000000000000000000000000000000000000004309 211.0
HFD2_k127_1981936_3 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 514.0
HFD2_k127_1981936_30 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000006341 207.0
HFD2_k127_1981936_31 Rieske 2Fe-2S K00479 - - 0.00000000000000000000000000000000000000000000000000000003038 210.0
HFD2_k127_1981936_32 protein phosphatase 2C domain protein - - - 0.00000000000000000000000000000000000000000000000000000008568 221.0
HFD2_k127_1981936_33 Electron transfer DM13 - - - 0.00000000000000000000000000000000000000000000000000002224 194.0
HFD2_k127_1981936_34 - - - - 0.00000000000000000000000000000000000000000000000000006072 192.0
HFD2_k127_1981936_35 RNA polymerase sigma factor, sigma-70 family K03090 GO:0000988,GO:0000990,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0006629,GO:0006950,GO:0006979,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016987,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034059,GO:0036293,GO:0042221,GO:0042594,GO:0043175,GO:0043254,GO:0043562,GO:0044087,GO:0044238,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0070417,GO:0070482,GO:0071496,GO:0071704,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000000000000000000000000000000018 199.0
HFD2_k127_1981936_36 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000005398 197.0
HFD2_k127_1981936_37 Protein of unknown function (DUF1345) - - - 0.00000000000000000000000000000000000000000000000005181 188.0
HFD2_k127_1981936_38 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000002464 194.0
HFD2_k127_1981936_39 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors - - - 0.000000000000000000000000000000000000000000002102 174.0
HFD2_k127_1981936_4 cobalamin binding K20450 - 5.4.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 467.0
HFD2_k127_1981936_40 - - - - 0.000000000000000000000000000000000000000009873 160.0
HFD2_k127_1981936_41 Cupin - - - 0.00000000000000000000000000000000000000003847 158.0
HFD2_k127_1981936_42 ACT domain protein - - - 0.00000000000000000000000000000000000004442 146.0
HFD2_k127_1981936_43 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.177 0.0000000000000000000000000000000000007318 153.0
HFD2_k127_1981936_44 Transcriptional regulator - - - 0.000000000000000000000000000000000001082 149.0
HFD2_k127_1981936_45 PFAM helix-turn-helix HxlR type - - - 0.0000000000000000000000000000000007053 138.0
HFD2_k127_1981936_46 Methyltransferase domain - - - 0.000000000000000000000000000000003201 136.0
HFD2_k127_1981936_47 LuxR family transcriptional regulator - - - 0.000000000000000000000000000000004655 141.0
HFD2_k127_1981936_48 Bacterial transcriptional repressor C-terminal - - - 0.000000000000000000000000000004101 128.0
HFD2_k127_1981936_49 Competence-damaged protein K03743 - 3.5.1.42 0.00000000000000000000000000006585 121.0
HFD2_k127_1981936_5 helix_turn _helix lactose operon repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 454.0
HFD2_k127_1981936_50 belongs to the sigma-70 factor family, ECF subfamily - - - 0.00000000000000000000000004479 113.0
HFD2_k127_1981936_51 Belongs to the CinA family - - - 0.000000000000000000000001847 113.0
HFD2_k127_1981936_52 transcriptional regulator K19333 - - 0.00000000000000000000004254 110.0
HFD2_k127_1981936_54 antisigma factor binding K04749 - - 0.000000000000001298 80.0
HFD2_k127_1981936_55 diguanylate cyclase - - - 0.000000000000003124 86.0
HFD2_k127_1981936_57 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006355,GO:0006401,GO:0006402,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0017148,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045927,GO:0045934,GO:0046483,GO:0046700,GO:0048518,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000001068 74.0
HFD2_k127_1981936_59 Thioesterase-like superfamily - - - 0.0000000003796 70.0
HFD2_k127_1981936_6 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 434.0
HFD2_k127_1981936_60 Bacterial regulatory proteins, tetR family - - - 0.00000000435 64.0
HFD2_k127_1981936_61 Histidine kinase-like ATPase domain - - - 0.000000006179 64.0
HFD2_k127_1981936_62 anti-sigma regulatory factor K04757 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036094,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 2.7.11.1 0.000000008289 62.0
HFD2_k127_1981936_64 amino acid activation for nonribosomal peptide biosynthetic process K01337,K20276 - 3.4.21.50 0.0000003824 52.0
HFD2_k127_1981936_65 Universal stress protein - - - 0.0001342 53.0
HFD2_k127_1981936_66 Histidine kinase-like ATPase domain - - - 0.0002042 49.0
HFD2_k127_1981936_67 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B) K04757 GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 2.7.11.1 0.0003989 50.0
HFD2_k127_1981936_7 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 422.0
HFD2_k127_1981936_8 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 420.0
HFD2_k127_1981936_9 WYL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 372.0
HFD2_k127_2023967_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1410.0
HFD2_k127_2023967_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 6.405e-247 774.0
HFD2_k127_2023967_10 membrane protein terC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 392.0
HFD2_k127_2023967_11 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 387.0
HFD2_k127_2023967_12 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 385.0
HFD2_k127_2023967_13 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 324.0
HFD2_k127_2023967_14 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 314.0
HFD2_k127_2023967_15 Histidine biosynthesis protein K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 305.0
HFD2_k127_2023967_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 285.0
HFD2_k127_2023967_17 Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol K15520 - 2.3.1.189 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001802 280.0
HFD2_k127_2023967_18 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001383 269.0
HFD2_k127_2023967_19 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002226 267.0
HFD2_k127_2023967_2 Oligopeptidase F K08602 - - 9.105e-243 773.0
HFD2_k127_2023967_20 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000001026 257.0
HFD2_k127_2023967_21 Protein of unknown function (DUF664) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003273 252.0
HFD2_k127_2023967_22 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003152 259.0
HFD2_k127_2023967_23 heme binding K06401,K21472 - - 0.000000000000000000000000000000000000000000000000000000000000000005724 245.0
HFD2_k127_2023967_24 Aminomethyltransferase folate-binding domain K06980 - - 0.0000000000000000000000000000000000000000000000000000000000002439 222.0
HFD2_k127_2023967_25 dioxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000004156 205.0
HFD2_k127_2023967_26 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000005509 192.0
HFD2_k127_2023967_27 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000000000000000001164 176.0
HFD2_k127_2023967_28 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000007683 171.0
HFD2_k127_2023967_29 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000003417 158.0
HFD2_k127_2023967_3 Anthranilate synthase component I, N terminal region K01657 - 4.1.3.27 6.68e-242 757.0
HFD2_k127_2023967_30 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000006456 133.0
HFD2_k127_2023967_31 - - - - 0.0000000000000000000000000000008376 131.0
HFD2_k127_2023967_32 PFAM AIG2 family protein - - - 0.000000000000000000000000000005572 133.0
HFD2_k127_2023967_35 Domain of unknown function (DUF4129) - - - 0.00000000000000000000000119 112.0
HFD2_k127_2023967_36 YjbR - - - 0.000000000000000216 86.0
HFD2_k127_2023967_38 Signal peptidase K13280 - 3.4.21.89 0.00002329 52.0
HFD2_k127_2023967_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 509.0
HFD2_k127_2023967_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 514.0
HFD2_k127_2023967_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 509.0
HFD2_k127_2023967_7 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 495.0
HFD2_k127_2023967_8 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006361 477.0
HFD2_k127_2023967_9 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000909 427.0
HFD2_k127_2033474_0 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 283.0
HFD2_k127_2033474_1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000576 270.0
HFD2_k127_2033474_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003715 261.0
HFD2_k127_2033474_3 PFAM Phospholipid glycerol acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000008372 221.0
HFD2_k127_2033474_4 Fasciclin - GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043207,GO:0044403,GO:0044419,GO:0044421,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071944,GO:0075136 - 0.00000000000000000000000000000000000000000000000000006725 193.0
HFD2_k127_2033474_5 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.0000000000000000000000000000000000000001379 165.0
HFD2_k127_2033474_6 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000000000000000000000003651 151.0
HFD2_k127_2033474_7 Anti-sigma-K factor rskA - - - 0.0000000000000000000000006774 112.0
HFD2_k127_2033474_8 Putative collagen-binding domain of a collagenase - - - 0.000000000000001033 90.0
HFD2_k127_2033474_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000002342 82.0
HFD2_k127_2056818_0 ATPase family associated with various cellular activities (AAA) K01338 - 3.4.21.53 0.0 1019.0
HFD2_k127_2056818_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 619.0
HFD2_k127_2056818_10 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 355.0
HFD2_k127_2056818_11 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 323.0
HFD2_k127_2056818_12 Arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 304.0
HFD2_k127_2056818_13 Peptidase C26 K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 297.0
HFD2_k127_2056818_14 Hypothetical methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008007 280.0
HFD2_k127_2056818_15 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001105 289.0
HFD2_k127_2056818_16 Protein of unknown function (DUF2662) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001331 283.0
HFD2_k127_2056818_17 6-phosphogluconolactonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004705 284.0
HFD2_k127_2056818_18 Sigma factor PP2C-like phosphatases K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000001513 254.0
HFD2_k127_2056818_19 SpoU rRNA Methylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000378 245.0
HFD2_k127_2056818_2 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 607.0
HFD2_k127_2056818_20 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000001933 233.0
HFD2_k127_2056818_21 DNA repair protein - - - 0.0000000000000000000000000000000000000000000000000000000000007721 219.0
HFD2_k127_2056818_22 Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP K01004 - 2.7.8.24 0.0000000000000000000000000000000000000003573 162.0
HFD2_k127_2056818_23 Forkhead associated domain - - - 0.000000000000000000000000000000000000005461 155.0
HFD2_k127_2056818_24 - - - - 0.00000000000000000000000000000000005807 136.0
HFD2_k127_2056818_25 - - - - 0.00000000000000000000000000000000005881 143.0
HFD2_k127_2056818_26 DNA-binding transcription factor activity K18996 - - 0.0000000000000000000000000000000007799 134.0
HFD2_k127_2056818_27 - - - - 0.000000000000000000000000000000004961 144.0
HFD2_k127_2056818_29 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00382 - 1.8.1.4 0.00000000000000000002038 90.0
HFD2_k127_2056818_3 Cell cycle protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 602.0
HFD2_k127_2056818_30 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000001729 91.0
HFD2_k127_2056818_31 Pkd domain containing protein - - - 0.00000000000001889 87.0
HFD2_k127_2056818_32 - - - - 0.00085 45.0
HFD2_k127_2056818_4 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 575.0
HFD2_k127_2056818_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 538.0
HFD2_k127_2056818_6 Penicillin binding protein transpeptidase domain K05364 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 532.0
HFD2_k127_2056818_7 Reductase C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 461.0
HFD2_k127_2056818_8 Pectinacetylesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 372.0
HFD2_k127_2056818_9 Protein of unknown function (DUF3048) C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 373.0
HFD2_k127_2073050_0 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 2.858e-219 689.0
HFD2_k127_2073050_1 Cys/Met metabolism PLP-dependent enzyme K01739 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009844 503.0
HFD2_k127_2073050_10 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000002447 218.0
HFD2_k127_2073050_11 Guanylyl transferase CofC like K14941 - 2.7.7.68 0.00000000000000000000000000000000000000000000000000002484 196.0
HFD2_k127_2073050_12 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000001266 188.0
HFD2_k127_2073050_13 - - - - 0.0000000000000000000000000000001809 128.0
HFD2_k127_2073050_14 Multicopper oxidase - - - 0.00000000001301 73.0
HFD2_k127_2073050_2 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 499.0
HFD2_k127_2073050_3 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 388.0
HFD2_k127_2073050_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 336.0
HFD2_k127_2073050_5 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 332.0
HFD2_k127_2073050_7 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000008678 269.0
HFD2_k127_2073050_8 PFAM Wyosine base formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006993 248.0
HFD2_k127_2073050_9 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000003832 216.0
HFD2_k127_21025_0 Glycine cleavage system P-protein K00281,K00283 - 1.4.4.2 0.0 1315.0
HFD2_k127_21025_1 Glycine cleavage T-protein C-terminal barrel domain K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 476.0
HFD2_k127_21025_10 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001844 239.0
HFD2_k127_21025_11 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000000000000000000000000000000000000000000000001494 235.0
HFD2_k127_21025_12 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000008921 233.0
HFD2_k127_21025_13 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001287 253.0
HFD2_k127_21025_14 pfkB family carbohydrate kinase K00882 - 2.7.1.56 0.000000000000000000000000000000000000000000000000000000000000001028 230.0
HFD2_k127_21025_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000001724 224.0
HFD2_k127_21025_16 Copper amine oxidase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000001013 218.0
HFD2_k127_21025_17 Histidine triad (Hit) protein K02503 - - 0.000000000000000000000000000000000000000000000000000001438 195.0
HFD2_k127_21025_19 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000006138 179.0
HFD2_k127_21025_2 metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 361.0
HFD2_k127_21025_20 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000076 179.0
HFD2_k127_21025_21 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000001042 167.0
HFD2_k127_21025_22 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000001178 168.0
HFD2_k127_21025_25 diguanylate cyclase - - - 0.000000000000000000000000000000005157 144.0
HFD2_k127_21025_26 Survival protein SurE K03787 - 3.1.3.5 0.00000000000000000000000000000009631 134.0
HFD2_k127_21025_28 - - - - 0.0000000000002985 81.0
HFD2_k127_21025_29 - - - - 0.0000000351 58.0
HFD2_k127_21025_3 Pyridoxal-dependent decarboxylase conserved domain K01634 - 4.1.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 319.0
HFD2_k127_21025_30 TIGRFAM anti-anti-sigma factor K04749 - - 0.00002597 51.0
HFD2_k127_21025_31 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0002994 52.0
HFD2_k127_21025_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 325.0
HFD2_k127_21025_5 SOS response associated peptidase (SRAP) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 299.0
HFD2_k127_21025_6 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 290.0
HFD2_k127_21025_7 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 290.0
HFD2_k127_21025_8 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007008 274.0
HFD2_k127_21025_9 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005518 261.0
HFD2_k127_214963_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.17.4.1 0.0 1229.0
HFD2_k127_214963_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 4.203e-308 960.0
HFD2_k127_214963_10 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000001563 189.0
HFD2_k127_214963_11 COG0346 Lactoylglutathione lyase and related lyases K07032 - - 0.000000000000000000000000000000000000000000491 168.0
HFD2_k127_214963_13 - - - - 0.0000000000000000000000000000655 128.0
HFD2_k127_214963_14 Protein of unknown function (DUF983) - - - 0.00000000000000000000004701 103.0
HFD2_k127_214963_15 LysM domain - - - 0.00000132 56.0
HFD2_k127_214963_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 8.531e-239 747.0
HFD2_k127_214963_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 1.308e-200 632.0
HFD2_k127_214963_4 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 489.0
HFD2_k127_214963_5 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 447.0
HFD2_k127_214963_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 342.0
HFD2_k127_214963_7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 313.0
HFD2_k127_214963_8 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000004965 249.0
HFD2_k127_214963_9 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000002317 205.0
HFD2_k127_222216_0 E1-E2 ATPase K01533 - 3.6.3.4 1.706e-258 814.0
HFD2_k127_222216_1 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 520.0
HFD2_k127_222216_10 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000714 175.0
HFD2_k127_222216_11 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000002021 167.0
HFD2_k127_222216_12 YCII-related domain - - - 0.000000000000000000000000000000000001796 141.0
HFD2_k127_222216_13 MerR, DNA binding - - - 0.000000000000000000000000000000000007735 153.0
HFD2_k127_222216_14 helix_turn_helix, Arsenical Resistance Operon Repressor - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0044212,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000266 136.0
HFD2_k127_222216_15 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000001727 111.0
HFD2_k127_222216_16 O-methyltransferase - - - 0.00000000000001074 85.0
HFD2_k127_222216_17 Copper binding proteins, plastocyanin/azurin family - - - 0.00009115 53.0
HFD2_k127_222216_2 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 499.0
HFD2_k127_222216_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00529 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 400.0
HFD2_k127_222216_4 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001904 242.0
HFD2_k127_222216_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000001957 220.0
HFD2_k127_222216_6 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000006948 209.0
HFD2_k127_222216_7 Putative methyltransferase K15942 - 2.1.1.288 0.000000000000000000000000000000000000000000000000000000002936 204.0
HFD2_k127_222216_8 - - - - 0.0000000000000000000000000000000000000000000000000000003601 202.0
HFD2_k127_222216_9 - - - - 0.00000000000000000000000000000000000000000000000002034 183.0
HFD2_k127_2224861_0 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 526.0
HFD2_k127_2224861_1 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 451.0
HFD2_k127_2224861_11 Dodecin K09165 - - 0.000004154 53.0
HFD2_k127_2224861_2 PFAM ROK family K00845,K00886 - 2.7.1.2,2.7.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000002727 263.0
HFD2_k127_2224861_3 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004873 257.0
HFD2_k127_2224861_4 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001311 246.0
HFD2_k127_2224861_5 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000005222 174.0
HFD2_k127_2224861_6 SnoaL-like domain - - - 0.00000000000000000000000000000000001348 139.0
HFD2_k127_2224861_7 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000002662 139.0
HFD2_k127_2224861_8 PFAM Phosphoglycerate mutase K08296 - - 0.000000000000000000000000000000001395 136.0
HFD2_k127_2224861_9 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000000008067 104.0
HFD2_k127_2370452_0 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 6.099e-234 730.0
HFD2_k127_2370452_1 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 1.485e-204 651.0
HFD2_k127_2370452_10 dehydratase - - - 0.000000000000000000000000000000000000000000000000000366 191.0
HFD2_k127_2370452_11 BetI-type transcriptional repressor, C-terminal - - - 0.0000000000000000000000000000000000000000000000000004668 191.0
HFD2_k127_2370452_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000007544 190.0
HFD2_k127_2370452_13 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000003912 202.0
HFD2_k127_2370452_14 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000004599 196.0
HFD2_k127_2370452_15 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000002033 121.0
HFD2_k127_2370452_2 Acyl-CoA dehydrogenase, C-terminal domain K00248,K14448 - 1.3.8.1,1.3.8.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 516.0
HFD2_k127_2370452_3 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 417.0
HFD2_k127_2370452_4 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 407.0
HFD2_k127_2370452_5 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 369.0
HFD2_k127_2370452_6 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 342.0
HFD2_k127_2370452_7 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003508 285.0
HFD2_k127_2370452_8 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001246 249.0
HFD2_k127_2370452_9 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000001238 209.0
HFD2_k127_2430137_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.521e-241 757.0
HFD2_k127_2430137_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 446.0
HFD2_k127_2430137_2 Cytochrome b(C-terminal)/b6/petD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 382.0
HFD2_k127_2430137_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 334.0
HFD2_k127_2430137_4 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 304.0
HFD2_k127_2430137_5 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 295.0
HFD2_k127_2430137_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001242 274.0
HFD2_k127_2430137_7 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000005329 226.0
HFD2_k127_2430137_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000004531 214.0
HFD2_k127_2430137_9 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000312 59.0
HFD2_k127_2448452_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1453.0
HFD2_k127_2448452_1 acyl-CoA dehydrogenase - - - 1.752e-226 706.0
HFD2_k127_2448452_10 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 430.0
HFD2_k127_2448452_11 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K01459 - 3.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 417.0
HFD2_k127_2448452_12 dihydroorotate dehydrogenase activity K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 347.0
HFD2_k127_2448452_13 membrane protein terC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 344.0
HFD2_k127_2448452_14 Major Facilitator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 307.0
HFD2_k127_2448452_15 Glucose dehydrogenase C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002649 292.0
HFD2_k127_2448452_16 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003397 291.0
HFD2_k127_2448452_17 PFAM Sodium hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000001058 248.0
HFD2_k127_2448452_18 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000003448 213.0
HFD2_k127_2448452_2 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term K00441 - 1.12.98.1 8.043e-217 676.0
HFD2_k127_2448452_3 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 2.257e-213 680.0
HFD2_k127_2448452_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 2.64e-207 651.0
HFD2_k127_2448452_5 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 621.0
HFD2_k127_2448452_6 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 599.0
HFD2_k127_2448452_7 AlkA N-terminal domain K13529 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 576.0
HFD2_k127_2448452_8 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 573.0
HFD2_k127_2448452_9 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 450.0
HFD2_k127_2477442_0 fumarylacetoacetate (FAA) hydrolase K05921 - 4.1.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 469.0
HFD2_k127_2477442_1 cytochrome P-450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 435.0
HFD2_k127_2477442_2 Alpha beta hydrolase K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000002022 184.0
HFD2_k127_2477442_3 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000002021 177.0
HFD2_k127_2477442_4 transcriptional regulator - - - 0.0000000000000000000000000000000001089 142.0
HFD2_k127_2477442_5 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000004574 108.0
HFD2_k127_2495936_0 Pyruvate formate lyase-activating protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 516.0
HFD2_k127_2495936_1 ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 327.0
HFD2_k127_2495936_2 Bacterial extracellular solute-binding protein K17329 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 332.0
HFD2_k127_2495936_3 Cbs domain - - - 0.00000000000000001371 91.0
HFD2_k127_2554577_0 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 432.0
HFD2_k127_2554577_1 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 374.0
HFD2_k127_2554577_2 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K16201 - - 0.00000000000000000000000000000000000000000000000000000000000002717 228.0
HFD2_k127_2554577_3 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000000001779 107.0
HFD2_k127_2554577_4 Phage integrase family - - - 0.0000002742 54.0
HFD2_k127_2554577_5 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0005621 42.0
HFD2_k127_2649170_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 1.057e-222 693.0
HFD2_k127_2649170_1 Belongs to the glycosyl hydrolase 13 family K01214,K02438 - 3.2.1.196,3.2.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 468.0
HFD2_k127_2649170_10 XdhC and CoxI family - - - 0.00000000000000000000000000000000000000000000001598 173.0
HFD2_k127_2649170_11 Protein of unknown function (DUF501) K09009 - - 0.0000000000000000000000000000000000000000000002566 177.0
HFD2_k127_2649170_12 MobA-like NTP transferase domain K07141,K19190 - 1.1.1.328,2.7.7.76 0.00000000000000000000000000000000000000001857 160.0
HFD2_k127_2649170_13 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000001216 156.0
HFD2_k127_2649170_14 universal stress protein - - - 0.00000000000000000000000000000000007924 148.0
HFD2_k127_2649170_15 cysteine-type peptidase activity K21471 - - 0.000000000000000000000000000000001268 143.0
HFD2_k127_2649170_16 Ppx/GppA phosphatase family - - - 0.000000000000000001046 91.0
HFD2_k127_2649170_17 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000001892 74.0
HFD2_k127_2649170_2 von Willebrand factor (vWF) type A domain K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 467.0
HFD2_k127_2649170_3 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 439.0
HFD2_k127_2649170_4 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007217 435.0
HFD2_k127_2649170_5 ATPase associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 423.0
HFD2_k127_2649170_6 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 407.0
HFD2_k127_2649170_7 von Willebrand factor, type A K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 387.0
HFD2_k127_2649170_8 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 301.0
HFD2_k127_2649170_9 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002655 246.0
HFD2_k127_2664259_0 PFAM carboxyl transferase - - - 4.813e-253 794.0
HFD2_k127_2664259_1 Class-II DAHP synthetase family K01626 - 2.5.1.54 7.457e-232 725.0
HFD2_k127_2664259_10 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 466.0
HFD2_k127_2664259_11 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K20940 - 1.14.13.218 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 472.0
HFD2_k127_2664259_12 DNA primase, small subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 444.0
HFD2_k127_2664259_13 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 424.0
HFD2_k127_2664259_14 Homocysteine S-methyltransferase K00544,K00548 - 2.1.1.13,2.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 404.0
HFD2_k127_2664259_15 Peptidase M1, membrane alanine aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 409.0
HFD2_k127_2664259_16 Mandelate racemase muconate lactonizing enzyme K02549,K19802,K21617 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113,5.1.1.20,5.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005782 398.0
HFD2_k127_2664259_17 F420-dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 388.0
HFD2_k127_2664259_18 PFAM Metallo-beta-lactamase superfamily - GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 335.0
HFD2_k127_2664259_19 PFAM Peptidase family S58 K18572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 329.0
HFD2_k127_2664259_2 ABC transporter transmembrane region K06147 - - 2.057e-205 663.0
HFD2_k127_2664259_20 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 321.0
HFD2_k127_2664259_21 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 320.0
HFD2_k127_2664259_22 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 307.0
HFD2_k127_2664259_23 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 306.0
HFD2_k127_2664259_24 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 300.0
HFD2_k127_2664259_25 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 305.0
HFD2_k127_2664259_26 Acetyltransferase (isoleucine patch K00661 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 2.3.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 293.0
HFD2_k127_2664259_27 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 299.0
HFD2_k127_2664259_28 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 291.0
HFD2_k127_2664259_29 alpha-ribazole phosphatase activity K02226,K15634 - 3.1.3.73,5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 284.0
HFD2_k127_2664259_3 Flavin-binding monooxygenase-like K14520 - 1.14.13.84 1.957e-196 632.0
HFD2_k127_2664259_30 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000000001454 258.0
HFD2_k127_2664259_31 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001293 259.0
HFD2_k127_2664259_32 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007248 263.0
HFD2_k127_2664259_33 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002885 252.0
HFD2_k127_2664259_34 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002845 251.0
HFD2_k127_2664259_35 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000003205 212.0
HFD2_k127_2664259_36 Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP K01004 GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24 0.00000000000000000000000000000000000000000000009031 178.0
HFD2_k127_2664259_37 5-methyl-5,6,7,8-tetrahydromethanopterin-dependent methyltransferase activity - - - 0.00000000000000000000000000000000000000000003207 170.0
HFD2_k127_2664259_38 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000001576 168.0
HFD2_k127_2664259_4 alcohol dehydrogenase K00153 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.306 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 608.0
HFD2_k127_2664259_40 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000001564 141.0
HFD2_k127_2664259_41 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000000006033 140.0
HFD2_k127_2664259_42 response to heat K07090 - - 0.000000000000000000000000000000007562 140.0
HFD2_k127_2664259_44 Histidine kinase - - - 0.00000000000000000000000000001541 134.0
HFD2_k127_2664259_45 YhhN family - - - 0.000000000000000000000000001788 119.0
HFD2_k127_2664259_46 CoA binding domain - - - 0.0000000000000000000002631 110.0
HFD2_k127_2664259_47 glyoxalase III activity - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944 - 0.000000000001145 74.0
HFD2_k127_2664259_49 Domain of unknown function (DUF4352) - - - 0.00007471 53.0
HFD2_k127_2664259_5 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004186 571.0
HFD2_k127_2664259_6 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 557.0
HFD2_k127_2664259_7 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 557.0
HFD2_k127_2664259_8 DegT/DnrJ/EryC1/StrS aminotransferase family K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 545.0
HFD2_k127_2664259_9 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 525.0
HFD2_k127_2669688_0 Succinyl-CoA ligase like flavodoxin domain - - - 1.298e-227 744.0
HFD2_k127_2669688_1 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 6.043e-213 681.0
HFD2_k127_2669688_10 ERCC4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 390.0
HFD2_k127_2669688_11 with different specificities (related to short-chain alcohol - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 369.0
HFD2_k127_2669688_12 Nucleotidyl transferase K21210 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 333.0
HFD2_k127_2669688_13 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007567 342.0
HFD2_k127_2669688_14 Branched-chain amino acid transport K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 311.0
HFD2_k127_2669688_15 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 298.0
HFD2_k127_2669688_16 Branched-chain amino acid ATP-binding cassette transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001485 304.0
HFD2_k127_2669688_17 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000746 285.0
HFD2_k127_2669688_18 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001267 273.0
HFD2_k127_2669688_19 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002938 272.0
HFD2_k127_2669688_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 569.0
HFD2_k127_2669688_20 Belongs to the peptidase M50B family - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001843 275.0
HFD2_k127_2669688_21 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007638 270.0
HFD2_k127_2669688_22 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000002701 229.0
HFD2_k127_2669688_23 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000002813 227.0
HFD2_k127_2669688_24 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000003354 223.0
HFD2_k127_2669688_25 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000002222 241.0
HFD2_k127_2669688_26 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000004623 213.0
HFD2_k127_2669688_27 Glycoside-hydrolase family GH114 - - - 0.00000000000000000000000000000000000000000000000000000008684 211.0
HFD2_k127_2669688_28 Peptidase C26 - - - 0.0000000000000000000000000000000000000000000000000000007558 211.0
HFD2_k127_2669688_29 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000005717 202.0
HFD2_k127_2669688_3 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 529.0
HFD2_k127_2669688_30 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K20276 - - 0.00000000000000000000000000000000000000000000000000006018 214.0
HFD2_k127_2669688_31 GDP-mannose 4,6 dehydratase K21214 - - 0.0000000000000000000000000000000000000000000000000006775 197.0
HFD2_k127_2669688_32 Glycoside-hydrolase family GH114 - - - 0.000000000000000000000000000000000000000000000000002133 205.0
HFD2_k127_2669688_33 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000008539 179.0
HFD2_k127_2669688_34 Histidine kinase - - - 0.000000000000000000000000000000000000000000009049 175.0
HFD2_k127_2669688_35 Universal stress protein family - - - 0.0000000000000000000000000000000000000001181 166.0
HFD2_k127_2669688_36 - - - - 0.00000000000000000000000000000000002752 151.0
HFD2_k127_2669688_37 protein domain, possibly involved in tellurite resistance - - - 0.0000000000000000000000000000000001761 137.0
HFD2_k127_2669688_38 FMN binding K03809 - 1.6.5.2 0.000000000000000000000000000000000397 138.0
HFD2_k127_2669688_39 transcriptional regulator - - - 0.000000000000000000000000000000007929 137.0
HFD2_k127_2669688_4 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 514.0
HFD2_k127_2669688_40 Sigma-70 region 2 - - - 0.0000000000000000000000000000003783 131.0
HFD2_k127_2669688_41 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000002721 133.0
HFD2_k127_2669688_42 Belongs to the small heat shock protein (HSP20) family K13993 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564 - 0.0000000000000000000000000005258 118.0
HFD2_k127_2669688_43 translation release factor activity - - - 0.0000000000000000000000000008446 127.0
HFD2_k127_2669688_44 PAS domain - - - 0.000000000000000000002768 101.0
HFD2_k127_2669688_45 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000007799 96.0
HFD2_k127_2669688_46 PFAM Sporulation and spore germination - - - 0.00000000000000000194 97.0
HFD2_k127_2669688_47 CBS domains - - - 0.0000000000000005123 80.0
HFD2_k127_2669688_48 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000000000003273 74.0
HFD2_k127_2669688_5 Glucose inhibited division protein A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008699 448.0
HFD2_k127_2669688_50 - - - - 0.00000003359 62.0
HFD2_k127_2669688_51 Belongs to the universal stress protein A family - - - 0.00000599 56.0
HFD2_k127_2669688_52 - - - - 0.0007433 52.0
HFD2_k127_2669688_6 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 442.0
HFD2_k127_2669688_7 epimerase dehydratase K01710,K08678,K21211 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 429.0
HFD2_k127_2669688_8 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005925 413.0
HFD2_k127_2669688_9 Domain of unknown function (DUF3492) K21011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 410.0
HFD2_k127_2671186_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1091.0
HFD2_k127_2671186_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.745e-280 893.0
HFD2_k127_2671186_10 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 421.0
HFD2_k127_2671186_11 ABC-type polar amino acid transport system ATPase component K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 383.0
HFD2_k127_2671186_12 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 370.0
HFD2_k127_2671186_13 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 347.0
HFD2_k127_2671186_14 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 341.0
HFD2_k127_2671186_15 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 335.0
HFD2_k127_2671186_16 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 333.0
HFD2_k127_2671186_17 NMT1/THI5 like K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 316.0
HFD2_k127_2671186_18 PFAM 2-nitropropane dioxygenase NPD K02371 - 1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 295.0
HFD2_k127_2671186_19 Polar amino acid ABC transporter K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003998 282.0
HFD2_k127_2671186_2 Aminoacyl-tRNA editing domain K01881 - 6.1.1.15 4.502e-275 856.0
HFD2_k127_2671186_20 with chaperone activity, ATP-binding subunit K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001857 264.0
HFD2_k127_2671186_21 DSBA oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000006019 229.0
HFD2_k127_2671186_22 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016667,GO:0016684,GO:0019725,GO:0020012,GO:0030312,GO:0030682,GO:0042221,GO:0042592,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000006065 222.0
HFD2_k127_2671186_23 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000004011 222.0
HFD2_k127_2671186_24 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000000000000000000000000000000000000000000000000000000005139 209.0
HFD2_k127_2671186_26 - - - - 0.000000000000000000000000000000000000000000000000000006082 193.0
HFD2_k127_2671186_27 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000000000000000005879 177.0
HFD2_k127_2671186_28 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000001285 163.0
HFD2_k127_2671186_29 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000001148 153.0
HFD2_k127_2671186_3 Peptidase dimerisation domain - - - 2.111e-209 667.0
HFD2_k127_2671186_30 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000004442 128.0
HFD2_k127_2671186_31 SnoaL-like domain - - - 0.0000000000000000000000000000000488 132.0
HFD2_k127_2671186_32 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000000000000000004228 99.0
HFD2_k127_2671186_33 Protein of unknown function (DUF503) K09764 - - 0.0000000000000007631 80.0
HFD2_k127_2671186_34 Chorismate mutase type II K04092 - 5.4.99.5 0.0000000009765 68.0
HFD2_k127_2671186_35 ribosomal protein L7Ae L30e S12e Gadd45 K07742 - - 0.000000001932 63.0
HFD2_k127_2671186_36 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.00006702 53.0
HFD2_k127_2671186_37 Beta-lactamase - - - 0.00008328 46.0
HFD2_k127_2671186_38 - - - - 0.0002521 51.0
HFD2_k127_2671186_4 Participates in both transcription termination and antitermination K02600 - - 1.998e-198 626.0
HFD2_k127_2671186_5 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 593.0
HFD2_k127_2671186_6 geranylgeranyl reductase K21401 - 1.3.99.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 521.0
HFD2_k127_2671186_7 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 489.0
HFD2_k127_2671186_8 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006069 473.0
HFD2_k127_2671186_9 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 438.0
HFD2_k127_2686253_0 Squalene-hopene cyclase N-terminal domain K06045 - 4.2.1.129,5.4.99.17 1.05e-263 826.0
HFD2_k127_2686253_1 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008548 563.0
HFD2_k127_2686253_10 phytoene synthase K02291 GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001657 278.0
HFD2_k127_2686253_11 Squalene phytoene synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003342 263.0
HFD2_k127_2686253_12 belongs to the sigma-70 factor family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000001407 240.0
HFD2_k127_2686253_13 Aminoglycoside 2'-N-acetyltransferase K17840 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008080,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016020,GO:0016137,GO:0016139,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017001,GO:0017144,GO:0030647,GO:0030649,GO:0034069,GO:0044237,GO:0044248,GO:0044464,GO:0047921,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901575,GO:1901657,GO:1901658 2.3.1.59 0.000000000000000000000000000000000000000000000000000000000006035 218.0
HFD2_k127_2686253_14 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000001408 201.0
HFD2_k127_2686253_15 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000002378 165.0
HFD2_k127_2686253_16 YCII-related domain - - - 0.00000000000000000000000000000000000000001267 162.0
HFD2_k127_2686253_17 - - - - 0.0000000000000000000000000000000000006451 144.0
HFD2_k127_2686253_18 Peptidoglycan-binding domain 1 protein K07260,K21449 - 3.4.17.14 0.00000000000000000000000000000000002641 154.0
HFD2_k127_2686253_19 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000007393 121.0
HFD2_k127_2686253_2 Glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 565.0
HFD2_k127_2686253_20 Belongs to the 'phage' integrase family - - - 0.0000000000000000003598 98.0
HFD2_k127_2686253_21 Bacterial regulatory proteins, tetR family - - - 0.0000001829 62.0
HFD2_k127_2686253_22 transcriptional regulator - - - 0.0001887 52.0
HFD2_k127_2686253_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 488.0
HFD2_k127_2686253_4 squalene-associated FAD-dependent desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 436.0
HFD2_k127_2686253_5 Taurine catabolism dioxygenase TauD, TfdA family K22303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 402.0
HFD2_k127_2686253_6 PFAM glycosidase, PH1107-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 397.0
HFD2_k127_2686253_7 Predicted Permease Membrane Region K07085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 337.0
HFD2_k127_2686253_8 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 303.0
HFD2_k127_2686253_9 Threonyl alanyl tRNA synthetase SAD K07050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006645 295.0
HFD2_k127_2695967_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 506.0
HFD2_k127_2695967_1 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009079 348.0
HFD2_k127_2695967_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000002473 243.0
HFD2_k127_2695967_3 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000049 238.0
HFD2_k127_2695967_4 endonuclease activity - - - 0.00000000000000000000000000000000000000000000000000000004361 214.0
HFD2_k127_2695967_5 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000003256 189.0
HFD2_k127_2695967_6 Transcriptional regulator - - - 0.0000000000000000000000000000000000000001009 164.0
HFD2_k127_2695967_7 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000007097 138.0
HFD2_k127_2695967_8 Alpha/beta hydrolase family - - - 0.000000000000004876 85.0
HFD2_k127_2707812_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.0 1235.0
HFD2_k127_2707812_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1189.0
HFD2_k127_2707812_10 ATPase, P-type K12952 - - 4.699e-222 713.0
HFD2_k127_2707812_100 Protein of unknown function (DUF559) - - - 0.0000000004603 70.0
HFD2_k127_2707812_101 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.0000001432 56.0
HFD2_k127_2707812_102 serine threonine protein kinase - - - 0.000000314 64.0
HFD2_k127_2707812_11 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 1.038e-213 677.0
HFD2_k127_2707812_12 Acyl-CoA dehydrogenase, C-terminal domain - - - 5.989e-198 623.0
HFD2_k127_2707812_13 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 599.0
HFD2_k127_2707812_14 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 620.0
HFD2_k127_2707812_15 Domain of unknown function (DUF4162) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 530.0
HFD2_k127_2707812_16 Alcohol dehydrogenase GroES-like domain K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 523.0
HFD2_k127_2707812_17 Thiolase, C-terminal domain K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 535.0
HFD2_k127_2707812_18 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 523.0
HFD2_k127_2707812_19 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 501.0
HFD2_k127_2707812_2 Major facilitator Superfamily - - - 1.197e-282 887.0
HFD2_k127_2707812_20 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 450.0
HFD2_k127_2707812_21 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 450.0
HFD2_k127_2707812_22 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 439.0
HFD2_k127_2707812_23 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 438.0
HFD2_k127_2707812_24 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007787 445.0
HFD2_k127_2707812_25 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007752 430.0
HFD2_k127_2707812_26 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008755 423.0
HFD2_k127_2707812_27 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006281 422.0
HFD2_k127_2707812_28 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008574 406.0
HFD2_k127_2707812_29 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 408.0
HFD2_k127_2707812_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.348e-274 850.0
HFD2_k127_2707812_30 C-terminal domain of 1-Cys peroxiredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 387.0
HFD2_k127_2707812_31 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 392.0
HFD2_k127_2707812_32 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 381.0
HFD2_k127_2707812_33 PFAM ATPase associated with various cellular activities, AAA_5 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 392.0
HFD2_k127_2707812_34 DNA helicase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 398.0
HFD2_k127_2707812_35 Glycosyl hydrolases family 18 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 376.0
HFD2_k127_2707812_36 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 363.0
HFD2_k127_2707812_37 Glycosylase K05522 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 342.0
HFD2_k127_2707812_38 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005896 358.0
HFD2_k127_2707812_39 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 336.0
HFD2_k127_2707812_4 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 1.299e-266 859.0
HFD2_k127_2707812_40 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 331.0
HFD2_k127_2707812_41 Peptidoglycan-binding domain 1 protein K01227,K01448,K03791,K13277,K17733 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016787,GO:0017171,GO:0018104,GO:0019538,GO:0030203,GO:0030312,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.2.1.96,3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 333.0
HFD2_k127_2707812_42 von Willebrand factor type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 333.0
HFD2_k127_2707812_43 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 329.0
HFD2_k127_2707812_44 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 320.0
HFD2_k127_2707812_45 Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 327.0
HFD2_k127_2707812_46 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 314.0
HFD2_k127_2707812_47 Tetrapyrrole (Corrin/Porphyrin) Methylases K02303,K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 305.0
HFD2_k127_2707812_48 carboxylic acid catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 305.0
HFD2_k127_2707812_49 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 313.0
HFD2_k127_2707812_5 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.18e-251 784.0
HFD2_k127_2707812_50 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 301.0
HFD2_k127_2707812_51 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 287.0
HFD2_k127_2707812_52 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000964 292.0
HFD2_k127_2707812_53 Cell envelope-related transcriptional attenuator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007228 291.0
HFD2_k127_2707812_54 helix_turn_helix isocitrate lyase regulation K02624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001634 283.0
HFD2_k127_2707812_55 Belongs to the pirin family K06911 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001022 279.0
HFD2_k127_2707812_56 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005882 291.0
HFD2_k127_2707812_57 NlpC/P60 family K21471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000545 281.0
HFD2_k127_2707812_58 ADP-ribose pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006217 267.0
HFD2_k127_2707812_59 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001733 272.0
HFD2_k127_2707812_6 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 1.949e-242 766.0
HFD2_k127_2707812_60 Phosphoadenosine phosphosulfate reductase family K00390 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004604,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016667,GO:0016671,GO:0019344,GO:0019752,GO:0040007,GO:0043436,GO:0043866,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000169 256.0
HFD2_k127_2707812_61 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005695 267.0
HFD2_k127_2707812_62 Sugar (and other) transporter K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001395 260.0
HFD2_k127_2707812_63 subfamily IA, variant 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006695 262.0
HFD2_k127_2707812_64 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000001923 244.0
HFD2_k127_2707812_65 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000002965 241.0
HFD2_k127_2707812_66 lipid binding K14954,K14955 GO:0003674,GO:0005102,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008289,GO:0009405,GO:0009605,GO:0009607,GO:0009966,GO:0010469,GO:0010646,GO:0016020,GO:0020012,GO:0023051,GO:0030312,GO:0030545,GO:0030682,GO:0031982,GO:0035091,GO:0042783,GO:0042785,GO:0043167,GO:0043168,GO:0043207,GO:0043226,GO:0043227,GO:0043230,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044421,GO:0044464,GO:0048018,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051812,GO:0051832,GO:0051834,GO:0051861,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0065009,GO:0071944,GO:0075136,GO:0097367,GO:0097691,GO:0098772,GO:1903561 - 0.00000000000000000000000000000000000000000000000000000000000000000002929 241.0
HFD2_k127_2707812_67 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.000000000000000000000000000000000000000000000000000000000000000001309 232.0
HFD2_k127_2707812_68 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000601 239.0
HFD2_k127_2707812_69 - - - - 0.0000000000000000000000000000000000000000000000000000000008646 208.0
HFD2_k127_2707812_7 AMP-binding enzyme K00666,K01897 - 6.2.1.3 7.176e-238 754.0
HFD2_k127_2707812_70 lysR family - - - 0.000000000000000000000000000000000000000000000000000000004771 211.0
HFD2_k127_2707812_71 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000001862 211.0
HFD2_k127_2707812_72 Oxidoreductase family, NAD-binding Rossmann fold K00010 - 1.1.1.18,1.1.1.369 0.000000000000000000000000000000000000000000000000001437 195.0
HFD2_k127_2707812_73 nUDIX hydrolase - GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 - 0.0000000000000000000000000000000000000000000000001747 185.0
HFD2_k127_2707812_74 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000001564 197.0
HFD2_k127_2707812_75 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000005605 183.0
HFD2_k127_2707812_76 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000005619 168.0
HFD2_k127_2707812_77 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000001099 174.0
HFD2_k127_2707812_78 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000000004293 166.0
HFD2_k127_2707812_79 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000000000004433 164.0
HFD2_k127_2707812_8 synthetase K18688 - 6.2.1.42 3.757e-234 737.0
HFD2_k127_2707812_80 Mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000881 168.0
HFD2_k127_2707812_81 competence protein COMEC - - - 0.0000000000000000000000000000000000000003877 173.0
HFD2_k127_2707812_82 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000004239 151.0
HFD2_k127_2707812_83 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000123 152.0
HFD2_k127_2707812_84 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000002501 158.0
HFD2_k127_2707812_85 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000003251 149.0
HFD2_k127_2707812_86 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000006652 153.0
HFD2_k127_2707812_87 Protein of unknown function (DUF1697) - - - 0.00000000000000000000000000000000000001356 151.0
HFD2_k127_2707812_88 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000001054 141.0
HFD2_k127_2707812_9 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 8.219e-223 698.0
HFD2_k127_2707812_90 - - - - 0.000000000000000000000000000000005734 134.0
HFD2_k127_2707812_91 TIR domain - - - 0.00000000000000000000000000001575 135.0
HFD2_k127_2707812_92 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.0000000000000000000000002268 117.0
HFD2_k127_2707812_93 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000002936 113.0
HFD2_k127_2707812_94 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.0000000000000000000007461 102.0
HFD2_k127_2707812_95 Mycofactocin system - - - 0.00000000000000000001024 94.0
HFD2_k127_2707812_96 - - - - 0.0000000000000000003326 90.0
HFD2_k127_2707812_97 Prokaryotic phospholipase A2 - - - 0.000000000000000006918 89.0
HFD2_k127_2707812_98 component of anaerobic - - - 0.0000000000000008348 86.0
HFD2_k127_2707812_99 Psort location Cytoplasmic, score - - - 0.00000000000116 78.0
HFD2_k127_2735457_0 AMP-binding enzyme C-terminal domain K00666 - - 2.104e-248 776.0
HFD2_k127_2735457_1 PFAM AMP-dependent synthetase and ligase K00666 - - 7.459e-225 709.0
HFD2_k127_2735457_10 Evidence 4 Homologs of previously reported genes of - - - 0.00000006797 63.0
HFD2_k127_2735457_2 chorismate binding enzyme K02552 - 5.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 512.0
HFD2_k127_2735457_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 439.0
HFD2_k127_2735457_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 413.0
HFD2_k127_2735457_5 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 377.0
HFD2_k127_2735457_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 349.0
HFD2_k127_2735457_7 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001271 259.0
HFD2_k127_2735457_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000004633 223.0
HFD2_k127_2735457_9 Acyclic terpene utilisation family protein AtuA - - - 0.00000000000000000000000000000000000007644 145.0
HFD2_k127_2747161_0 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 469.0
HFD2_k127_2747161_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 401.0
HFD2_k127_2747161_10 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000002479 212.0
HFD2_k127_2747161_11 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000004023 204.0
HFD2_k127_2747161_12 - - - - 0.0000000000000000000000000000000000000000000000002118 180.0
HFD2_k127_2747161_13 Thiolase, C-terminal domain - - - 0.0000000000000000000004673 96.0
HFD2_k127_2747161_2 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 365.0
HFD2_k127_2747161_3 Multicopper K06324 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 371.0
HFD2_k127_2747161_4 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 359.0
HFD2_k127_2747161_5 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 345.0
HFD2_k127_2747161_6 Enoyl-CoA hydratase/isomerase K01692,K07546 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000001504 259.0
HFD2_k127_2747161_7 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001123 247.0
HFD2_k127_2747161_8 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000001353 239.0
HFD2_k127_2747161_9 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000001213 230.0
HFD2_k127_2750824_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1156.0
HFD2_k127_2750824_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 2.121e-252 790.0
HFD2_k127_2750824_10 Creatinase/Prolidase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 528.0
HFD2_k127_2750824_11 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 524.0
HFD2_k127_2750824_12 GlcNAc-PI de-N-acetylase K18455 - 3.5.1.115 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 482.0
HFD2_k127_2750824_13 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 453.0
HFD2_k127_2750824_14 lipolytic protein G-D-S-L family K01183 - 3.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 470.0
HFD2_k127_2750824_15 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 423.0
HFD2_k127_2750824_16 DNA polymerase LigD polymerase domain K01971,K10747 GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 422.0
HFD2_k127_2750824_17 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 435.0
HFD2_k127_2750824_18 YdjC-like protein K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009129 407.0
HFD2_k127_2750824_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 373.0
HFD2_k127_2750824_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 3.273e-240 756.0
HFD2_k127_2750824_20 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050790,GO:0050896,GO:0051340,GO:0051351,GO:0051716,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006447 371.0
HFD2_k127_2750824_21 lipolytic protein G-D-S-L family K01183 - 3.2.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 386.0
HFD2_k127_2750824_22 ABC transporter K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 380.0
HFD2_k127_2750824_23 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 352.0
HFD2_k127_2750824_24 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 351.0
HFD2_k127_2750824_25 Myo-inositol 2-dehydrogenase K18652 - 1.1.1.361 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 335.0
HFD2_k127_2750824_26 4-hydroxybenzoate 3-monooxygenase K00481 - 1.14.13.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 337.0
HFD2_k127_2750824_27 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 305.0
HFD2_k127_2750824_28 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000398 284.0
HFD2_k127_2750824_29 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000001162 274.0
HFD2_k127_2750824_3 WD40-like Beta Propeller Repeat - - - 3.395e-225 709.0
HFD2_k127_2750824_30 COG1082 Sugar phosphate isomerases epimerases K03335 - 4.2.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000006424 252.0
HFD2_k127_2750824_31 Belongs to the Nudix hydrolase family. NudC subfamily K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000007871 255.0
HFD2_k127_2750824_32 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008602 258.0
HFD2_k127_2750824_33 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000002684 214.0
HFD2_k127_2750824_34 Protein of unknown function (DUF664) - - - 0.0000000000000000000000000000000000000000000000000000000006545 207.0
HFD2_k127_2750824_35 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000676 205.0
HFD2_k127_2750824_36 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000007256 190.0
HFD2_k127_2750824_37 nuclease K01174,K07038 - 3.1.31.1 0.0000000000000000000000000000000000000000000000000009786 190.0
HFD2_k127_2750824_38 (ABC) transporter - - - 0.000000000000000000000000000000000000000000000000005437 194.0
HFD2_k127_2750824_39 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000001132 180.0
HFD2_k127_2750824_4 Thiamine pyrophosphate enzyme, central domain K03336 - 3.7.1.22 7.629e-221 701.0
HFD2_k127_2750824_40 - - - - 0.0000000000000000000000000000000000000001607 154.0
HFD2_k127_2750824_41 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000578 145.0
HFD2_k127_2750824_42 - - - - 0.000000000000000000000000000001311 139.0
HFD2_k127_2750824_44 positive regulation of acetylcholine metabolic process K06910 - - 0.000000000000000000000000246 115.0
HFD2_k127_2750824_45 - - - - 0.0000000000000000000003758 108.0
HFD2_k127_2750824_46 Uncharacterised nucleotidyltransferase - - - 0.000000000000000001105 99.0
HFD2_k127_2750824_47 ECF sigma factor K03088 - - 0.000000000000001324 87.0
HFD2_k127_2750824_48 Transposase - - - 0.000000000000006585 78.0
HFD2_k127_2750824_49 Transglutaminase-like superfamily - - - 0.00000000000002255 79.0
HFD2_k127_2750824_5 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 1.724e-209 662.0
HFD2_k127_2750824_52 DDE superfamily endonuclease - - - 0.00000000001318 67.0
HFD2_k127_2750824_53 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000001415 69.0
HFD2_k127_2750824_6 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 2.919e-201 654.0
HFD2_k127_2750824_7 e3 binding domain K00658 - 2.3.1.61 1.167e-197 627.0
HFD2_k127_2750824_8 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007262 552.0
HFD2_k127_2750824_9 MMPL family K06994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 569.0
HFD2_k127_2785401_0 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 0.0 1762.0
HFD2_k127_2785401_1 Domain of unknown function (DUF222) - - - 0.00000000000000000000000000000000000000000000000000000000789 203.0
HFD2_k127_2785401_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000001446 156.0
HFD2_k127_2785401_3 amine dehydrogenase activity - - - 0.0000007273 59.0
HFD2_k127_2790083_0 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 384.0
HFD2_k127_2790083_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001697 254.0
HFD2_k127_2790083_2 WD40 repeats - - - 0.000000000000000000000000000000000000000000000000000000000622 230.0
HFD2_k127_2790083_3 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000001782 180.0
HFD2_k127_2790083_4 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000008476 115.0
HFD2_k127_2790083_5 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000003834 103.0
HFD2_k127_2790083_6 Carboxylesterase family - - - 0.00000000005774 75.0
HFD2_k127_2790083_7 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.00000001015 69.0
HFD2_k127_2790083_8 - - - - 0.000001011 57.0
HFD2_k127_2790083_9 - - - - 0.000008054 52.0
HFD2_k127_2794203_0 N-terminal domain of (some) glycogen debranching enzymes - - - 1.159e-271 854.0
HFD2_k127_2794203_1 HD domain - - - 7.417e-220 693.0
HFD2_k127_2794203_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001155 230.0
HFD2_k127_2794203_11 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001461 226.0
HFD2_k127_2794203_12 Predicted membrane protein (DUF2231) - - - 0.0000000000000000000000000000000000000000000000000000000000009509 216.0
HFD2_k127_2794203_13 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000004448 154.0
HFD2_k127_2794203_14 OsmC-like protein - - - 0.00000000000000000000000000000000000004967 155.0
HFD2_k127_2794203_15 SnoaL-like domain - - - 0.000000000000000000000000000000000005233 141.0
HFD2_k127_2794203_16 branched-chain amino acid permease (azaleucine resistance) - - - 0.000000000000000000000000522 115.0
HFD2_k127_2794203_17 FtsX-like permease family - - - 0.0000000000000000000005935 112.0
HFD2_k127_2794203_18 Domain of unknown function (DUF333) K09712 - - 0.0000000000000223 82.0
HFD2_k127_2794203_2 Protein of unknown function (DUF1298) K00635 - 2.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006116 593.0
HFD2_k127_2794203_3 winged helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 535.0
HFD2_k127_2794203_4 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 523.0
HFD2_k127_2794203_5 ABC-2 type transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 503.0
HFD2_k127_2794203_6 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 479.0
HFD2_k127_2794203_7 cyclic nucleotide binding K15762 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 479.0
HFD2_k127_2794203_8 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 460.0
HFD2_k127_2794203_9 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 356.0
HFD2_k127_2804350_0 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 617.0
HFD2_k127_2804350_1 Lysylphosphatidylglycerol synthase TM region K07027,K20468 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418 419.0
HFD2_k127_2804350_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 368.0
HFD2_k127_2804350_3 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 321.0
HFD2_k127_2804350_4 endonuclease III K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 317.0
HFD2_k127_2804350_5 - - - - 0.00000000000000000000000000000000003482 136.0
HFD2_k127_2804350_6 - - - - 0.000000000000002503 78.0
HFD2_k127_2804350_7 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000001251 53.0
HFD2_k127_2804350_8 Methylamine utilisation protein MauE - - - 0.00004721 48.0
HFD2_k127_2825182_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1157.0
HFD2_k127_2825182_1 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 563.0
HFD2_k127_2825182_2 GMC oxidoreductase K00108 - 1.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 411.0
HFD2_k127_2825182_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 321.0
HFD2_k127_2825182_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000156 248.0
HFD2_k127_2825182_5 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000001359 219.0
HFD2_k127_2825182_6 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000003911 167.0
HFD2_k127_2825182_7 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000000002424 148.0
HFD2_k127_2825182_8 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000000000525 124.0
HFD2_k127_2825182_9 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000006369 82.0
HFD2_k127_2874034_0 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006346 485.0
HFD2_k127_2874034_1 Belongs to the thiolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000628 445.0
HFD2_k127_2874034_10 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006432 278.0
HFD2_k127_2874034_11 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004535 271.0
HFD2_k127_2874034_12 ABC-type branched-chain amino acid transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009063 277.0
HFD2_k127_2874034_13 Ankyrin repeats (3 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002616 259.0
HFD2_k127_2874034_14 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001514 260.0
HFD2_k127_2874034_15 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000001755 226.0
HFD2_k127_2874034_16 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000001201 189.0
HFD2_k127_2874034_17 sigma-70 region 2 K03088 - - 0.0000000000000000004658 97.0
HFD2_k127_2874034_18 - K01992 - - 0.0000000000003345 79.0
HFD2_k127_2874034_19 Cytochrome b K03887 - - 0.000000000009574 77.0
HFD2_k127_2874034_2 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 405.0
HFD2_k127_2874034_20 Exporter of polyketide K01992 - - 0.000191 50.0
HFD2_k127_2874034_3 F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 355.0
HFD2_k127_2874034_4 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 340.0
HFD2_k127_2874034_5 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 335.0
HFD2_k127_2874034_6 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 316.0
HFD2_k127_2874034_7 Enoyl-(Acyl carrier protein) reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 311.0
HFD2_k127_2874034_8 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 295.0
HFD2_k127_2874034_9 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000483 289.0
HFD2_k127_2892403_0 Papain family cysteine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006375 382.0
HFD2_k127_2892403_1 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000000000000000000000002627 226.0
HFD2_k127_2892403_2 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000005581 188.0
HFD2_k127_2892403_3 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000217 179.0
HFD2_k127_2892403_4 methyltransferase K15942 - 2.1.1.288 0.0000000000000000000000000000000000000000000003612 170.0
HFD2_k127_2892403_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000458 158.0
HFD2_k127_2892403_6 - - - - 0.000000000000000000004979 105.0
HFD2_k127_2892403_7 Pfam Secreted repeat of K19519 - - 0.00000000000000001026 91.0
HFD2_k127_2892403_8 Chagasin family peptidase inhibitor I42 - - - 0.00000004586 59.0
HFD2_k127_2892403_9 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000001812 61.0
HFD2_k127_293759_0 DNA polymerase alpha chain like domain K02337 - 2.7.7.7 0.0 1771.0
HFD2_k127_293759_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1454.0
HFD2_k127_293759_10 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 497.0
HFD2_k127_293759_11 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006841 473.0
HFD2_k127_293759_12 ABC transporter K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 449.0
HFD2_k127_293759_13 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 463.0
HFD2_k127_293759_14 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 452.0
HFD2_k127_293759_15 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 457.0
HFD2_k127_293759_16 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428 443.0
HFD2_k127_293759_17 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 410.0
HFD2_k127_293759_18 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 417.0
HFD2_k127_293759_19 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 416.0
HFD2_k127_293759_2 Protein of unknown function, DUF255 K06888 - - 1.757e-260 818.0
HFD2_k127_293759_20 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 407.0
HFD2_k127_293759_21 Cell cycle protein K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 399.0
HFD2_k127_293759_22 Aminotransferase class I and II K14261 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 384.0
HFD2_k127_293759_23 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 364.0
HFD2_k127_293759_24 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 371.0
HFD2_k127_293759_25 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 358.0
HFD2_k127_293759_26 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 355.0
HFD2_k127_293759_27 transport, permease protein K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 344.0
HFD2_k127_293759_28 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 325.0
HFD2_k127_293759_29 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 296.0
HFD2_k127_293759_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 2.298e-232 727.0
HFD2_k127_293759_30 Inositol monophosphatase K01092 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000002625 276.0
HFD2_k127_293759_31 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000001789 263.0
HFD2_k127_293759_32 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000002128 255.0
HFD2_k127_293759_33 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003043 245.0
HFD2_k127_293759_34 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000001935 241.0
HFD2_k127_293759_35 transport, permease protein K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000003443 239.0
HFD2_k127_293759_36 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000101 231.0
HFD2_k127_293759_37 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000001411 217.0
HFD2_k127_293759_38 Alanine racemase, N-terminal domain K06997 - - 0.0000000000000000000000000000000000000000000000000000000003656 209.0
HFD2_k127_293759_39 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters - - - 0.0000000000000000000000000000000000000000000000000000000007321 212.0
HFD2_k127_293759_4 Acyl-CoA dehydrogenase, N-terminal domain - - - 2.286e-211 661.0
HFD2_k127_293759_40 regulation of cell shape - - - 0.000000000000000000000000000000000000000000000000000001078 203.0
HFD2_k127_293759_41 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 6.3.2.4 0.00000000000000000000000000000000000000000000000000001548 204.0
HFD2_k127_293759_42 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA K09772 - - 0.0000000000000000000000000000000000000000000000000007742 198.0
HFD2_k127_293759_43 Protein of unknown function (DUF2587) - - - 0.000000000000000000000000000000000000000000000000002344 188.0
HFD2_k127_293759_44 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000006744 181.0
HFD2_k127_293759_45 Nitroreductase family - - - 0.00000000000000000000000000000000000000000005539 172.0
HFD2_k127_293759_46 Lipoate-protein ligase - - - 0.0000000000000000000000000000000000000008972 157.0
HFD2_k127_293759_47 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000001876 161.0
HFD2_k127_293759_48 MraZ protein, putative antitoxin-like K03925 - - 0.00000000000000000000000000000000000523 142.0
HFD2_k127_293759_49 GDP-mannose mannosyl hydrolase activity K08310 - 3.6.1.67 0.00000000000000000000000000000000001239 141.0
HFD2_k127_293759_5 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.435e-200 637.0
HFD2_k127_293759_50 - - - - 0.00000000000000000000000000000000002451 136.0
HFD2_k127_293759_56 PFAM Sporulation and spore germination - - - 0.000009471 55.0
HFD2_k127_293759_6 tRNA synthetases class I (C) catalytic domain K15526 - 6.3.1.13 2.176e-196 616.0
HFD2_k127_293759_7 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009829 577.0
HFD2_k127_293759_8 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 537.0
HFD2_k127_293759_9 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008639 492.0
HFD2_k127_2946948_0 PFAM tRNA synthetases class I (E and Q), catalytic domain K01886 - 6.1.1.18 9.557e-291 901.0
HFD2_k127_2946948_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 6.812e-283 876.0
HFD2_k127_2946948_10 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 464.0
HFD2_k127_2946948_11 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 431.0
HFD2_k127_2946948_12 F420-dependent oxidoreductase, MSMEG_3544 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 381.0
HFD2_k127_2946948_13 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 345.0
HFD2_k127_2946948_14 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 302.0
HFD2_k127_2946948_15 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001836 254.0
HFD2_k127_2946948_16 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000009784 247.0
HFD2_k127_2946948_17 endonuclease activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004874 256.0
HFD2_k127_2946948_18 radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000263 239.0
HFD2_k127_2946948_19 Belongs to the DegT DnrJ EryC1 family K13310 - 2.6.1.106 0.00000000000000000000000000000000000000000000000000000000000000001298 237.0
HFD2_k127_2946948_2 Catalyzes the reversible hydration of fumarate to (S)- malate K01676,K01678,K03780 - 4.2.1.2,4.2.1.32 4.177e-279 865.0
HFD2_k127_2946948_20 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000002441 207.0
HFD2_k127_2946948_21 PFAM regulatory protein MarR - - - 0.00000000000000000000000000000000000000000000000000001036 193.0
HFD2_k127_2946948_22 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000001343 188.0
HFD2_k127_2946948_23 Haemolysin-III related K11068 - - 0.0000000000000000000000000000000000000000000000001101 186.0
HFD2_k127_2946948_24 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000005902 186.0
HFD2_k127_2946948_25 metal cluster binding K06940 - - 0.0000000000000000000000000000000000000000001184 168.0
HFD2_k127_2946948_26 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000001205 160.0
HFD2_k127_2946948_27 lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000001437 167.0
HFD2_k127_2946948_28 Peptidase family M23 - - - 0.00000000000000000000000000000000000000002989 167.0
HFD2_k127_2946948_29 transcriptional regulator - - - 0.000000000000000000000001041 109.0
HFD2_k127_2946948_3 ABC transporter - - - 4.096e-240 752.0
HFD2_k127_2946948_30 Protein of unknown function (DUF2752) - - - 0.000000000000000001104 91.0
HFD2_k127_2946948_31 - - - - 0.00000000000000004502 87.0
HFD2_k127_2946948_32 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000006998 81.0
HFD2_k127_2946948_33 - - - - 0.0000000000002475 81.0
HFD2_k127_2946948_34 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000002183 63.0
HFD2_k127_2946948_35 Methyltransferase domain - - - 0.0008535 47.0
HFD2_k127_2946948_4 glycine radical enzyme, YjjI family - - - 1.335e-223 705.0
HFD2_k127_2946948_5 Belongs to the DEAD box helicase family K05592,K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 4.382e-220 696.0
HFD2_k127_2946948_6 Belongs to the amidase family K01426 - 3.5.1.4 1.664e-213 674.0
HFD2_k127_2946948_7 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000798 623.0
HFD2_k127_2946948_8 DNA ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 526.0
HFD2_k127_2946948_9 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 541.0
HFD2_k127_298538_0 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006216 456.0
HFD2_k127_298538_1 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 419.0
HFD2_k127_298538_10 - - - - 0.0007648 49.0
HFD2_k127_298538_2 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008503 350.0
HFD2_k127_298538_3 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000001552 214.0
HFD2_k127_298538_4 MaoC like domain - - - 0.00000000000000000000000000000000000000000001112 165.0
HFD2_k127_298538_5 Protein of unknown function (DUF1345) - - - 0.00000000000000000000000000000000000000000001248 180.0
HFD2_k127_298538_6 - - - - 0.0000000000000000000000000000000001188 136.0
HFD2_k127_298538_7 - - - - 0.0000000000001503 75.0
HFD2_k127_298538_8 PDZ DHR GLGF domain protein K07177 - - 0.00000009865 63.0
HFD2_k127_298538_9 PAS fold - - - 0.00001846 57.0
HFD2_k127_3005146_0 o-methyltransferase K21377 - 2.1.1.302 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 507.0
HFD2_k127_3005146_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007411 518.0
HFD2_k127_3005146_2 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 357.0
HFD2_k127_3005146_3 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000005664 184.0
HFD2_k127_3005146_4 Branched-chain amino acid transport system / permease component K02057 - - 0.0003276 44.0
HFD2_k127_3063495_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 1.887e-310 964.0
HFD2_k127_3063495_1 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 559.0
HFD2_k127_3063495_2 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 341.0
HFD2_k127_3063495_3 carboxylic ester hydrolase activity K01259,K19311 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 297.0
HFD2_k127_3063495_4 Saccharopine dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002627 271.0
HFD2_k127_3063495_5 membrane - - - 0.00000000000000000000000000000000000000000004227 169.0
HFD2_k127_3135385_0 homoserine dehydrogenase - - - 2.215e-213 670.0
HFD2_k127_3135385_1 -O-antigen K02847,K02849,K21003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 452.0
HFD2_k127_3135385_10 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001297 250.0
HFD2_k127_3135385_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000299 246.0
HFD2_k127_3135385_12 O-acyltransferase activity K00661 - 2.3.1.79 0.000000000000000000000000000000000000000000000000000000006631 204.0
HFD2_k127_3135385_13 extracellular polysaccharide biosynthetic process K16692,K20998 - - 0.00000000000000000000000000000000000000000000000000161 196.0
HFD2_k127_3135385_14 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000007093 192.0
HFD2_k127_3135385_15 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000002636 170.0
HFD2_k127_3135385_16 Putative collagen-binding domain of a collagenase - - - 0.000000000000000000000000000000000000000004471 175.0
HFD2_k127_3135385_17 PFAM FecR protein K07279 - - 0.000000000000000000000000000000000000000006163 174.0
HFD2_k127_3135385_18 protein tyrosine kinase activity K20998 - - 0.000000000000000000000000000000000000000008511 165.0
HFD2_k127_3135385_19 metallocarboxypeptidase activity K14054 - - 0.0000000000000000000000000000000000000001832 160.0
HFD2_k127_3135385_2 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 422.0
HFD2_k127_3135385_20 JAB/MPN domain K21140 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006508,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016787,GO:0019344,GO:0019538,GO:0019752,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.13.1.6 0.000000000000000000000000000000000000001263 152.0
HFD2_k127_3135385_21 polysaccharide biosynthetic process - - - 0.00000000000000000000000000000000002834 151.0
HFD2_k127_3135385_22 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000009515 133.0
HFD2_k127_3135385_23 Glycosyl transferases group 1 - - - 0.00000000000000000008073 103.0
HFD2_k127_3135385_3 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 393.0
HFD2_k127_3135385_4 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006734 372.0
HFD2_k127_3135385_5 Nucleotidyl transferase K00978 - 2.7.7.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 364.0
HFD2_k127_3135385_6 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 334.0
HFD2_k127_3135385_7 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 300.0
HFD2_k127_3135385_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 300.0
HFD2_k127_3135385_9 Belongs to the sigma-70 factor family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002143 271.0
HFD2_k127_3156896_0 Uncharacterised protein family (UPF0182) K09118 - - 3.212e-284 902.0
HFD2_k127_3156896_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.387e-272 846.0
HFD2_k127_3156896_10 Chlorite dismutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008267 263.0
HFD2_k127_3156896_11 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004835 254.0
HFD2_k127_3156896_12 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000004552 246.0
HFD2_k127_3156896_13 Belongs to the peptidase S16 family K07177 - - 0.00000000000000000000000000000000000000000000000000000000000000279 237.0
HFD2_k127_3156896_14 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000001081 226.0
HFD2_k127_3156896_15 Golgi phosphoprotein 3 (GPP34) - - - 0.0000000000000000000000000000000000000000000000000000000000015 218.0
HFD2_k127_3156896_16 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000000000000000000000000000000000614 213.0
HFD2_k127_3156896_17 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000008377 226.0
HFD2_k127_3156896_18 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000003078 201.0
HFD2_k127_3156896_19 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000001033 196.0
HFD2_k127_3156896_2 transcriptional regulator - - - 1.417e-235 744.0
HFD2_k127_3156896_20 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000002768 167.0
HFD2_k127_3156896_21 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000003208 171.0
HFD2_k127_3156896_22 ThiS family K03636 - - 0.0000000000000000000000000000004446 125.0
HFD2_k127_3156896_23 nuclear chromosome segregation K19765 - - 0.000000000000000006424 97.0
HFD2_k127_3156896_24 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000002902 75.0
HFD2_k127_3156896_26 Peptidase family S58 - - - 0.00000000005991 66.0
HFD2_k127_3156896_27 Peptidase family S58 K01266 - 3.4.11.19 0.000000002647 64.0
HFD2_k127_3156896_28 - - - - 0.0000002406 59.0
HFD2_k127_3156896_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 1.454e-208 664.0
HFD2_k127_3156896_4 regulation of cell shape K04074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 508.0
HFD2_k127_3156896_5 PAC2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 384.0
HFD2_k127_3156896_6 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 372.0
HFD2_k127_3156896_7 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000825 367.0
HFD2_k127_3156896_8 Hydrolase of X-linked nucleoside diphosphate N terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 351.0
HFD2_k127_3156896_9 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005193 276.0
HFD2_k127_325172_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.0 1068.0
HFD2_k127_325172_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 4.66e-303 948.0
HFD2_k127_325172_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 526.0
HFD2_k127_325172_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006711 544.0
HFD2_k127_325172_12 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 501.0
HFD2_k127_325172_13 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 483.0
HFD2_k127_325172_14 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 448.0
HFD2_k127_325172_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 371.0
HFD2_k127_325172_16 acr, cog1565 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 362.0
HFD2_k127_325172_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 317.0
HFD2_k127_325172_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007856 301.0
HFD2_k127_325172_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000288 283.0
HFD2_k127_325172_2 protein synonym multiple resistance and pH homeostasis protein A K00341 - 1.6.5.3 1.375e-259 813.0
HFD2_k127_325172_20 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008184 245.0
HFD2_k127_325172_21 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000007366 205.0
HFD2_k127_325172_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000001343 188.0
HFD2_k127_325172_23 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000002127 198.0
HFD2_k127_325172_24 peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000006364 190.0
HFD2_k127_325172_25 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000001156 178.0
HFD2_k127_325172_26 peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000002098 176.0
HFD2_k127_325172_27 Choline/ethanolamine kinase - - - 0.000000000000000000000000000000000000000000001256 184.0
HFD2_k127_325172_28 pyridoxamine 5-phosphate - - - 0.000000000000000000000000000000000000000009676 158.0
HFD2_k127_325172_29 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000000001325 151.0
HFD2_k127_325172_3 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 6.611e-252 783.0
HFD2_k127_325172_30 glutamine amidotransferase - - - 0.00000000000000000000000000000000000003798 156.0
HFD2_k127_325172_31 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000003573 136.0
HFD2_k127_325172_32 Protein of unknown function (DUF559) - - - 0.00000000000000000005936 102.0
HFD2_k127_325172_33 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000005805 81.0
HFD2_k127_325172_34 HYR domain - - - 0.0000000002151 73.0
HFD2_k127_325172_4 protein synonym multiple resistance and pH homeostasis protein A K00341,K05565 - 1.6.5.3 6.066e-242 767.0
HFD2_k127_325172_5 Protein synonym NADH dehydrogenase I subunit M K00342 - 1.6.5.3 5.505e-240 764.0
HFD2_k127_325172_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 3.225e-232 721.0
HFD2_k127_325172_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 5.942e-209 660.0
HFD2_k127_325172_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 587.0
HFD2_k127_325172_9 ATPases associated with a variety of cellular activities K15738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006334 545.0
HFD2_k127_3300689_0 Protein involved in transcription factor activity, ATP binding, drug transporter activity, ATPase activity, metal ion binding, regulation of transcription, DNA-dependent, drug transport, metal ion transport, defense response to pathogen and response to antibiotic K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 402.0
HFD2_k127_3300689_1 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 353.0
HFD2_k127_3300689_10 membrane protein (DUF2078) - - - 0.0000000005644 66.0
HFD2_k127_3300689_11 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.0000004715 59.0
HFD2_k127_3300689_12 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000005539 52.0
HFD2_k127_3300689_13 membrane protein (DUF2078) K08982 - - 0.000004012 53.0
HFD2_k127_3300689_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000005062 174.0
HFD2_k127_3300689_3 Acetyltransferases including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000000000000000001516 170.0
HFD2_k127_3300689_4 Domain of unknown function (DUF2703) - - - 0.0000000000000000000000000000000000000000000001914 173.0
HFD2_k127_3300689_5 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000001113 138.0
HFD2_k127_3300689_6 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000005276 125.0
HFD2_k127_3300689_7 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000002081 78.0
HFD2_k127_3300689_9 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000007406 69.0
HFD2_k127_334026_0 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005814 591.0
HFD2_k127_334026_1 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 572.0
HFD2_k127_334026_10 Multicopper K06324 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005815 367.0
HFD2_k127_334026_11 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 339.0
HFD2_k127_334026_12 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006087 327.0
HFD2_k127_334026_13 transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 347.0
HFD2_k127_334026_14 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002464 287.0
HFD2_k127_334026_15 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001836 254.0
HFD2_k127_334026_16 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002453 252.0
HFD2_k127_334026_17 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000978 243.0
HFD2_k127_334026_18 response to heat K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000003158 234.0
HFD2_k127_334026_19 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000001053 214.0
HFD2_k127_334026_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 559.0
HFD2_k127_334026_20 PFAM DsrC family protein K11179 - - 0.0000000000000000000000000000000000000000009613 165.0
HFD2_k127_334026_21 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01259 - 3.4.11.5 0.0000000000000000000000000000000000000008595 152.0
HFD2_k127_334026_22 Thioredoxin-like domain K03671 - - 0.000000000000000000000000001204 125.0
HFD2_k127_334026_23 Domain of unknown function DUF302 - - - 0.000000000000000000000000002796 118.0
HFD2_k127_334026_24 Rhodanese-related sulfurtransferase - - - 0.000000000000000000000000007347 115.0
HFD2_k127_334026_25 Metal-sensitive transcriptional repressor - - - 0.00000000000000000000000002365 110.0
HFD2_k127_334026_26 o-methyltransferase K21377 - 2.1.1.302 0.000005445 60.0
HFD2_k127_334026_27 Pfam Zn-finger in ubiquitin-hydrolases and other protein K03455 - - 0.000006057 49.0
HFD2_k127_334026_3 Nad-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000554 502.0
HFD2_k127_334026_4 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 497.0
HFD2_k127_334026_5 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006933 468.0
HFD2_k127_334026_6 MMPL family K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000706 450.0
HFD2_k127_334026_7 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 424.0
HFD2_k127_334026_8 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 406.0
HFD2_k127_334026_9 B12 binding domain K22491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004999 354.0
HFD2_k127_338566_0 Histidine kinase K00936 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 604.0
HFD2_k127_338566_1 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 477.0
HFD2_k127_338566_10 Phosphatidylinositol - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 318.0
HFD2_k127_338566_11 Protein of unknown function (DUF3090) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001592 234.0
HFD2_k127_338566_12 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000002987 178.0
HFD2_k127_338566_13 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.000000000000000000000000000000000004589 139.0
HFD2_k127_338566_14 Protein of unknown function (DUF3107) - - - 0.000000000000000000001839 96.0
HFD2_k127_338566_15 DJ-1 PfpI family - - - 0.0000000000000000000651 89.0
HFD2_k127_338566_2 Electron transfer flavoprotein domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 462.0
HFD2_k127_338566_3 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 429.0
HFD2_k127_338566_4 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006295 404.0
HFD2_k127_338566_5 alpha/beta hydrolase fold K01066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 354.0
HFD2_k127_338566_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 346.0
HFD2_k127_338566_7 Transcriptional regulator - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009405,GO:0010468,GO:0010565,GO:0016020,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0044419,GO:0044464,GO:0050789,GO:0050794,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 329.0
HFD2_k127_338566_8 Histidine phosphatase superfamily (branch 1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 316.0
HFD2_k127_338566_9 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 314.0
HFD2_k127_3533289_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1272.0
HFD2_k127_3533289_1 MMPL family K06994 - - 2.531e-198 649.0
HFD2_k127_3533289_10 replication factor c K02341,K02343,K09384 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000001196 238.0
HFD2_k127_3533289_11 Pyridoxamine 5-phosphate - - - 0.000000000000000000000000000000000000000000000000000000002603 202.0
HFD2_k127_3533289_12 Type II secretion system (T2SS), protein F K12511 - - 0.00000000000000000000000000005838 133.0
HFD2_k127_3533289_13 unsaturated chondroitin disaccharide hydrolase activity K15532 - 3.2.1.172 0.0000000000000000000529 105.0
HFD2_k127_3533289_14 PFAM TadE family protein - - - 0.00000000000001166 78.0
HFD2_k127_3533289_15 Type ii secretion system K12510 - - 0.000000000002955 76.0
HFD2_k127_3533289_16 Belongs to the anti-sigma-factor antagonist family - - - 0.000004603 53.0
HFD2_k127_3533289_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 4.521e-198 625.0
HFD2_k127_3533289_3 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 572.0
HFD2_k127_3533289_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 427.0
HFD2_k127_3533289_5 Peptidase S8 and S53 subtilisin kexin sedolisin K17734 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008672 402.0
HFD2_k127_3533289_6 non-haem dioxygenase in morphine synthesis N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 391.0
HFD2_k127_3533289_7 type II secretion system protein E K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001885 284.0
HFD2_k127_3533289_8 spore germination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007227 273.0
HFD2_k127_3533289_9 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000003096 243.0
HFD2_k127_3533340_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 1.237e-264 839.0
HFD2_k127_3533340_1 4-hydroxyphenylacetate 3-hydroxylase N terminal K00483,K21726 - 1.14.13.166,1.14.13.29,1.14.14.9 2.629e-243 764.0
HFD2_k127_3533340_10 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000002081 237.0
HFD2_k127_3533340_11 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000008499 225.0
HFD2_k127_3533340_12 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000002361 193.0
HFD2_k127_3533340_13 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000001879 193.0
HFD2_k127_3533340_14 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000006962 181.0
HFD2_k127_3533340_15 Protein of unknown function (DUF2848) - - - 0.0000000000000000000000000000000000000037 164.0
HFD2_k127_3533340_16 FCD - - - 0.0000000000000000000000000000000000003144 149.0
HFD2_k127_3533340_17 PRC-barrel domain - - - 0.000000000000000000000000000000000001047 149.0
HFD2_k127_3533340_18 ChrR Cupin-like domain - - - 0.000000000000000000000000000000001145 140.0
HFD2_k127_3533340_19 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03406,K21009 - - 0.00000000000000000000000000000000199 149.0
HFD2_k127_3533340_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 561.0
HFD2_k127_3533340_20 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000003196 117.0
HFD2_k127_3533340_21 PRC-barrel domain - - - 0.00000000000000000000000008702 114.0
HFD2_k127_3533340_22 Domain of unknown function (DUF1989) - - - 0.000000000000000000000001674 111.0
HFD2_k127_3533340_23 Protein of unknown function (DUF3995) - - - 0.00000000000000005882 89.0
HFD2_k127_3533340_24 Flavin reductase like domain K09024 - - 0.00000000000001995 81.0
HFD2_k127_3533340_25 PhoQ Sensor - - - 0.000000000001978 81.0
HFD2_k127_3533340_26 - - - - 0.0000006092 57.0
HFD2_k127_3533340_27 FtsX-like permease family K02004 - - 0.000003314 61.0
HFD2_k127_3533340_28 PFAM transposase IS3 IS911 family protein K07483 - - 0.00004249 47.0
HFD2_k127_3533340_3 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 458.0
HFD2_k127_3533340_4 Peptidase S8 and S53 subtilisin kexin sedolisin K17734 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 406.0
HFD2_k127_3533340_5 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008346 388.0
HFD2_k127_3533340_6 involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 384.0
HFD2_k127_3533340_7 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 321.0
HFD2_k127_3533340_8 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001585 269.0
HFD2_k127_3533340_9 ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003431 253.0
HFD2_k127_3551318_0 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.0 1088.0
HFD2_k127_3551318_1 Nitrate reductase delta subunit - - - 0.0000000001166 72.0
HFD2_k127_3568889_0 beta-1,4-mannooligosaccharide phosphorylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 476.0
HFD2_k127_3568889_1 Trypsin-like serine protease - - - 0.000000000000000000000000000000000000000000000000000002468 201.0
HFD2_k127_3568889_2 metalloendopeptidase activity K03799 - - 0.00000000000000000000000000000000000000000000009725 180.0
HFD2_k127_3591271_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1485.0
HFD2_k127_3591271_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1237.0
HFD2_k127_3591271_10 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 532.0
HFD2_k127_3591271_11 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 535.0
HFD2_k127_3591271_12 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 524.0
HFD2_k127_3591271_13 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 477.0
HFD2_k127_3591271_14 Domain of unknown function (DUF4032) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 492.0
HFD2_k127_3591271_15 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 453.0
HFD2_k127_3591271_16 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008272,GO:0015698,GO:0016020,GO:0040007,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072348 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 447.0
HFD2_k127_3591271_17 sulfate ABC transporter K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009217 414.0
HFD2_k127_3591271_18 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 389.0
HFD2_k127_3591271_19 Binding-protein-dependent transport systems inner membrane component K02018,K15496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 356.0
HFD2_k127_3591271_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 1.965e-315 1001.0
HFD2_k127_3591271_20 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 332.0
HFD2_k127_3591271_21 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 333.0
HFD2_k127_3591271_22 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 331.0
HFD2_k127_3591271_23 Binding-protein-dependent transport system inner membrane component K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 317.0
HFD2_k127_3591271_24 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 313.0
HFD2_k127_3591271_25 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009576 313.0
HFD2_k127_3591271_26 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007097 317.0
HFD2_k127_3591271_27 Tetrapyrrole (Corrin/Porphyrin) Methylases K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 296.0
HFD2_k127_3591271_29 endonuclease activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004042 273.0
HFD2_k127_3591271_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 4.498e-259 806.0
HFD2_k127_3591271_30 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000006339 267.0
HFD2_k127_3591271_31 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000668 263.0
HFD2_k127_3591271_32 2Fe-2S -binding K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000001065 236.0
HFD2_k127_3591271_33 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000005574 246.0
HFD2_k127_3591271_34 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000001402 221.0
HFD2_k127_3591271_35 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000008649 195.0
HFD2_k127_3591271_36 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000001215 196.0
HFD2_k127_3591271_37 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.0000000000000000000000000000000000000000000000000007807 192.0
HFD2_k127_3591271_38 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000008141 187.0
HFD2_k127_3591271_39 Aldo/keto reductase family K18471 - - 0.00000000000000000000000000000000000000000000000003793 190.0
HFD2_k127_3591271_4 Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00124 - - 6.292e-250 790.0
HFD2_k127_3591271_40 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000007138 190.0
HFD2_k127_3591271_41 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000001092 161.0
HFD2_k127_3591271_42 Iron permease FTR1 K07243 - - 0.000000000000000000000000000000000000000008619 164.0
HFD2_k127_3591271_43 helix_turn_helix ASNC type - - - 0.000000000000000000000000000000000000000009557 171.0
HFD2_k127_3591271_44 Transcriptional regulator - - - 0.00000000000000000000000000000000000005621 153.0
HFD2_k127_3591271_45 SnoaL-like domain - - - 0.0000000000000000000000000000000008497 134.0
HFD2_k127_3591271_46 2-phosphosulpholactate phosphatase - - - 0.0000000000000000000000001035 117.0
HFD2_k127_3591271_47 cell cycle K05589,K13052 - - 0.000000000000000000000001774 109.0
HFD2_k127_3591271_48 EamA-like transporter family - - - 0.0000000000001277 82.0
HFD2_k127_3591271_5 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 2.033e-218 691.0
HFD2_k127_3591271_50 peptidoglycan-binding domain-containing protein - - - 0.00000003194 64.0
HFD2_k127_3591271_51 peptidoglycan-binding domain-containing protein - - - 0.0000005391 61.0
HFD2_k127_3591271_53 Domain of unknown function (DUF4260) - - - 0.0005941 48.0
HFD2_k127_3591271_6 Aminotransferase class-III K01845 - 5.4.3.8 4.495e-204 644.0
HFD2_k127_3591271_7 MazG nucleotide pyrophosphohydrolase domain K02499 - - 5.333e-199 632.0
HFD2_k127_3591271_8 Protein of unknown function (DUF933) K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 566.0
HFD2_k127_3591271_9 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006918 593.0
HFD2_k127_3604351_0 Heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 9.985e-211 662.0
HFD2_k127_3604351_1 Fe-S oxidoreductase - - - 2.994e-202 660.0
HFD2_k127_3604351_10 - - - - 0.0000000000000000000000000000000000000004219 162.0
HFD2_k127_3604351_11 Glycine cleavage H-protein - - - 0.00000000000000000000000000000000003142 139.0
HFD2_k127_3604351_12 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.000000000000000000000000000003804 121.0
HFD2_k127_3604351_2 PFAM Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 565.0
HFD2_k127_3604351_3 FAD binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 516.0
HFD2_k127_3604351_4 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004734 475.0
HFD2_k127_3604351_5 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 407.0
HFD2_k127_3604351_6 PFAM Biotin lipoate A B protein ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 304.0
HFD2_k127_3604351_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004141 244.0
HFD2_k127_3604351_8 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000005743 216.0
HFD2_k127_3604351_9 - - - - 0.000000000000000000000000000000000000000000000000000004513 202.0
HFD2_k127_3635352_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 9.637e-229 725.0
HFD2_k127_3635352_1 Bacterial lipid A biosynthesis acyltransferase K22311 - 2.3.1.265 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 363.0
HFD2_k127_3635352_2 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 325.0
HFD2_k127_3635352_3 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 315.0
HFD2_k127_3635352_4 HIT domain K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000000000188 224.0
HFD2_k127_3635352_5 - - - - 0.00000000000000000000000000000000000000000000000000000000009473 209.0
HFD2_k127_3642997_0 glycine cleavage T protein (aminomethyl transferase) K19191 - 1.5.3.19 0.0 1105.0
HFD2_k127_3642997_1 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 559.0
HFD2_k127_3642997_10 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000001275 244.0
HFD2_k127_3642997_11 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000000001965 226.0
HFD2_k127_3642997_12 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000000000008455 245.0
HFD2_k127_3642997_13 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000002333 226.0
HFD2_k127_3642997_14 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000003288 233.0
HFD2_k127_3642997_15 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000001285 218.0
HFD2_k127_3642997_16 competence protein COMEC - - - 0.00000000000000000000000000000000000000000000000000000001802 211.0
HFD2_k127_3642997_17 PFAM Prenyltransferase squalene oxidase - - - 0.0000000000000000000000000000000000000000000007152 179.0
HFD2_k127_3642997_18 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000002993 166.0
HFD2_k127_3642997_19 Subtilase family - - - 0.0000000000000000000000000000000000000003658 167.0
HFD2_k127_3642997_2 sulphate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 546.0
HFD2_k127_3642997_20 Secreted repeat of unknown function - - - 0.0000000000000000000000000000000000733 140.0
HFD2_k127_3642997_21 regulatory protein, arsR K03892 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000005312 134.0
HFD2_k127_3642997_22 YCII-related domain - - - 0.0000000000000000000000000000001882 126.0
HFD2_k127_3642997_23 Anti-sigma-K factor rskA - - - 0.000000000000000000000000002898 118.0
HFD2_k127_3642997_24 GYD domain - - - 0.000000000000000000000006605 106.0
HFD2_k127_3642997_25 - - - - 0.0000000000000000000223 108.0
HFD2_k127_3642997_26 Peptidoglycan-binding domain-containing protein - - - 0.00000009269 62.0
HFD2_k127_3642997_27 Belongs to the UPF0312 family - - - 0.00002808 55.0
HFD2_k127_3642997_3 Sarcosine oxidase beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 462.0
HFD2_k127_3642997_4 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 370.0
HFD2_k127_3642997_5 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 358.0
HFD2_k127_3642997_6 Esterase-like activity of phytase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000922 293.0
HFD2_k127_3642997_7 Tetrapyrrole (Corrin/Porphyrin) Methylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001888 277.0
HFD2_k127_3642997_8 N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005397 267.0
HFD2_k127_3642997_9 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001024 253.0
HFD2_k127_3654232_0 PFAM Type II secretion system protein E K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 541.0
HFD2_k127_3654232_1 Evidence 2b Function of strongly homologous gene K02282 - - 0.0000000000000000000000000000000000000000000000000003803 200.0
HFD2_k127_3654232_10 lactoylglutathione lyase activity - - - 0.00008576 51.0
HFD2_k127_3654232_2 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000002853 186.0
HFD2_k127_3654232_3 Pilus assembly protein K02279 - - 0.000000000000000000000000001278 125.0
HFD2_k127_3654232_4 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000611 108.0
HFD2_k127_3654232_5 - - - - 0.000000000000000000003216 109.0
HFD2_k127_3654232_6 Peptidase A24A, prepilin type IV K02654 - 3.4.23.43 0.0000000000000000002817 95.0
HFD2_k127_3654232_7 PAS domain K18350 - 2.7.13.3 0.0000000000002207 79.0
HFD2_k127_3654232_8 Type II secretion system (T2SS), protein F K12510 - - 0.000000000001033 78.0
HFD2_k127_3654232_9 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000219 78.0
HFD2_k127_366902_0 Belongs to the GcvT family - - - 0.0 1050.0
HFD2_k127_366902_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 327.0
HFD2_k127_366902_2 Electron transfer flavoprotein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004505 280.0
HFD2_k127_366902_3 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002141 265.0
HFD2_k127_366902_4 gntR family - - - 0.0000000000000000000000000000000946 132.0
HFD2_k127_3669395_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 5.817e-290 898.0
HFD2_k127_3669395_1 PFAM phenylalanine histidine ammonia-lyase K01745 - 4.3.1.3 6.797e-205 659.0
HFD2_k127_3669395_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418 516.0
HFD2_k127_3669395_3 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 499.0
HFD2_k127_3669395_4 deiminase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 463.0
HFD2_k127_3669395_5 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 450.0
HFD2_k127_3669395_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 287.0
HFD2_k127_3669395_7 Histidine kinase K07682 GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.0000000000000000000000000000000000000000000000000002388 203.0
HFD2_k127_3669395_8 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000001059 204.0
HFD2_k127_3670395_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1402.0
HFD2_k127_3670395_1 hydrogenase expression formation protein HypD K04654 - - 1.892e-210 659.0
HFD2_k127_3670395_10 PhoD-like phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 462.0
HFD2_k127_3670395_11 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 444.0
HFD2_k127_3670395_12 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 436.0
HFD2_k127_3670395_13 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 430.0
HFD2_k127_3670395_14 ribosomal rna small subunit methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 424.0
HFD2_k127_3670395_15 PFAM Bacterial domain of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008431 440.0
HFD2_k127_3670395_16 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 413.0
HFD2_k127_3670395_17 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 425.0
HFD2_k127_3670395_18 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 397.0
HFD2_k127_3670395_19 ATPases associated with a variety of cellular activities K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 390.0
HFD2_k127_3670395_2 Circularly permuted ATP-grasp type 2 - - - 7.113e-195 622.0
HFD2_k127_3670395_20 Dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 380.0
HFD2_k127_3670395_21 TOBE domain K02017,K02018 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 375.0
HFD2_k127_3670395_22 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000773 360.0
HFD2_k127_3670395_23 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009193 370.0
HFD2_k127_3670395_24 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009931 353.0
HFD2_k127_3670395_25 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 336.0
HFD2_k127_3670395_26 Pyridoxal phosphate biosynthetic protein PdxA K22024 - 1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 336.0
HFD2_k127_3670395_27 Molybdate ABC transporter K02017,K02018 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 302.0
HFD2_k127_3670395_28 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 299.0
HFD2_k127_3670395_29 Bacterial transglutaminase-like N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005284 280.0
HFD2_k127_3670395_3 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0016874,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 552.0
HFD2_k127_3670395_30 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003697 261.0
HFD2_k127_3670395_31 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005143 246.0
HFD2_k127_3670395_32 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000143 239.0
HFD2_k127_3670395_33 A predicted alpha-helical domain with a conserved ER motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000005798 250.0
HFD2_k127_3670395_34 Protein of unknown function (DUF971) K00471 - 1.14.11.1 0.0000000000000000000000000000000000000000000000000000000000003408 226.0
HFD2_k127_3670395_35 Diacylglycerol kinase K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000002754 218.0
HFD2_k127_3670395_36 PFAM globin K06886 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000004093 206.0
HFD2_k127_3670395_37 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000002272 214.0
HFD2_k127_3670395_38 YbaK prolyl-tRNA synthetase associated region - - - 0.000000000000000000000000000000000000000000000000000000009212 202.0
HFD2_k127_3670395_39 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000004369 187.0
HFD2_k127_3670395_4 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 542.0
HFD2_k127_3670395_40 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000001431 179.0
HFD2_k127_3670395_41 Domain of Unknown Function (DUF1206) - - - 0.00000000000000000000000000000000000000000003565 172.0
HFD2_k127_3670395_42 competence protein K03654 - 3.6.4.12 0.000000000000000000000000000000000000000004349 162.0
HFD2_k127_3670395_43 Methyltransferase domain - - - 0.00000000000000000000000000000000000003944 151.0
HFD2_k127_3670395_44 PAP2 superfamily K19302 - 3.6.1.27 0.0000000000000000000000000000000001418 142.0
HFD2_k127_3670395_45 EamA-like transporter family - - - 0.0000000000000000000000000000002315 135.0
HFD2_k127_3670395_46 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.000000000000000000000000662 108.0
HFD2_k127_3670395_47 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000001024 119.0
HFD2_k127_3670395_48 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000004906 91.0
HFD2_k127_3670395_49 Putative nucleotide-binding of sugar-metabolising enzyme K22129 - 2.7.1.219,2.7.1.220 0.000000000000006712 86.0
HFD2_k127_3670395_5 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016043,GO:0016829,GO:0016830,GO:0016833,GO:0022607,GO:0034214,GO:0042180,GO:0042181,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576,GO:1901661,GO:1901663 4.1.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 543.0
HFD2_k127_3670395_51 - - - - 0.000000000005188 73.0
HFD2_k127_3670395_53 Belongs to the UPF0312 family - - - 0.000007815 54.0
HFD2_k127_3670395_6 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 533.0
HFD2_k127_3670395_7 Phytanoyl-CoA dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 530.0
HFD2_k127_3670395_8 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0008652,GO:0008743,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046870,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007119 480.0
HFD2_k127_3670395_9 Glycine cleavage T-protein C-terminal barrel domain K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 457.0
HFD2_k127_3745080_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1086.0
HFD2_k127_3745080_1 PA domain - - - 2.258e-309 978.0
HFD2_k127_3745080_10 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 6.855e-200 631.0
HFD2_k127_3745080_11 Cell division protein FtsA K03569 - - 8.981e-199 623.0
HFD2_k127_3745080_12 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 589.0
HFD2_k127_3745080_13 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 582.0
HFD2_k127_3745080_14 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 553.0
HFD2_k127_3745080_15 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 552.0
HFD2_k127_3745080_16 Polysaccharide biosynthesis C-terminal domain K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 534.0
HFD2_k127_3745080_17 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 512.0
HFD2_k127_3745080_18 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 502.0
HFD2_k127_3745080_19 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 464.0
HFD2_k127_3745080_2 Phosphoribosylglycinamide synthetase, C domain K01945,K11788 - 6.3.3.1,6.3.4.13 3.62e-301 942.0
HFD2_k127_3745080_20 Cell cycle protein K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 461.0
HFD2_k127_3745080_21 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 458.0
HFD2_k127_3745080_22 Pfam Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 455.0
HFD2_k127_3745080_23 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 421.0
HFD2_k127_3745080_24 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000934 400.0
HFD2_k127_3745080_25 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 414.0
HFD2_k127_3745080_26 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 359.0
HFD2_k127_3745080_27 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009983 353.0
HFD2_k127_3745080_28 Phage shock protein A K03969 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008271 311.0
HFD2_k127_3745080_29 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 302.0
HFD2_k127_3745080_3 Glycosyl Transferase - - - 4.755e-281 885.0
HFD2_k127_3745080_30 Cysteine desulfurase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 293.0
HFD2_k127_3745080_31 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007004 262.0
HFD2_k127_3745080_32 phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit K00479,K00499 - 1.14.15.7 0.0000000000000000000000000000000000000000000000000000000000000000000000001271 261.0
HFD2_k127_3745080_33 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000007924 244.0
HFD2_k127_3745080_34 Domain of unknown function (DUF4262) - - - 0.000000000000000000000000000000000000000000000000000000000000000000007961 239.0
HFD2_k127_3745080_35 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000002568 231.0
HFD2_k127_3745080_36 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000001249 231.0
HFD2_k127_3745080_37 Histidine phosphatase superfamily (branch 1) K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000002506 227.0
HFD2_k127_3745080_38 COG1335 Amidases related to nicotinamidase - - - 0.000000000000000000000000000000000000000000000000000000003054 205.0
HFD2_k127_3745080_39 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.000000000000000000000000000000000000000000000000001357 188.0
HFD2_k127_3745080_4 VWA domain containing CoxE-like protein K07161 - - 6.805e-265 820.0
HFD2_k127_3745080_40 SURF1-like protein - GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944 - 0.000000000000000000000000000000000000000000000000003799 191.0
HFD2_k127_3745080_41 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000000005943 158.0
HFD2_k127_3745080_42 Family of unknown function (DUF5317) - - - 0.0000000000000000000000000000000000000000207 164.0
HFD2_k127_3745080_43 - K03571 - - 0.0000000000000000000000000000000000000127 150.0
HFD2_k127_3745080_44 - - - - 0.0000000000000000000000000000000000008877 148.0
HFD2_k127_3745080_45 Ribosomal L27 protein K02899 - - 0.000000000000000000000000000000002174 136.0
HFD2_k127_3745080_47 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000000000000000000000001386 114.0
HFD2_k127_3745080_48 EamA-like transporter family - - - 0.00000000000000000000003982 111.0
HFD2_k127_3745080_49 - - - - 0.0000000000000000000001198 99.0
HFD2_k127_3745080_5 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 8.966e-251 781.0
HFD2_k127_3745080_50 - - - - 0.0000000000000000106 90.0
HFD2_k127_3745080_51 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000866 79.0
HFD2_k127_3745080_53 - - - - 0.0000000711 58.0
HFD2_k127_3745080_54 STAS domain - - - 0.0000003589 57.0
HFD2_k127_3745080_6 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 1.497e-238 752.0
HFD2_k127_3745080_7 Ribonuclease E/G family K08300,K08301 - 3.1.26.12 1.222e-232 736.0
HFD2_k127_3745080_8 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 6.295e-227 727.0
HFD2_k127_3745080_9 ClpX C4-type zinc finger K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 2.394e-206 648.0
HFD2_k127_3825216_0 ABC transporter - - - 3.015e-301 932.0
HFD2_k127_3825216_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.325e-244 770.0
HFD2_k127_3825216_10 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 370.0
HFD2_k127_3825216_11 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 377.0
HFD2_k127_3825216_12 Sigma-70 region 3 K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 359.0
HFD2_k127_3825216_13 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 354.0
HFD2_k127_3825216_14 Pyridoxal-phosphate dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 347.0
HFD2_k127_3825216_15 inositol monophosphatase K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 342.0
HFD2_k127_3825216_16 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 317.0
HFD2_k127_3825216_17 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 306.0
HFD2_k127_3825216_18 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 326.0
HFD2_k127_3825216_19 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 322.0
HFD2_k127_3825216_2 ABC1 family - - - 2.904e-243 764.0
HFD2_k127_3825216_20 mannose-6-phosphate isomerase K01809 - 5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004454 276.0
HFD2_k127_3825216_21 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004661 268.0
HFD2_k127_3825216_22 Phosphorylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000003317 222.0
HFD2_k127_3825216_23 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000005241 204.0
HFD2_k127_3825216_24 heme binding K08259,K21472 - 3.4.24.75 0.0000000000000000000000000000000005267 138.0
HFD2_k127_3825216_25 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000001079 126.0
HFD2_k127_3825216_26 Urate oxidase N-terminal - - - 0.00000000000000000000000135 119.0
HFD2_k127_3825216_27 - - - - 0.000000000005279 79.0
HFD2_k127_3825216_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 6.456e-211 666.0
HFD2_k127_3825216_4 PFAM magnesium chelatase ChlI subunit K07391 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008045 585.0
HFD2_k127_3825216_5 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 515.0
HFD2_k127_3825216_6 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 443.0
HFD2_k127_3825216_7 Ribosomal protein S2 K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 409.0
HFD2_k127_3825216_8 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008354 411.0
HFD2_k127_3825216_9 Phage integrase, N-terminal SAM-like domain K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 389.0
HFD2_k127_3837249_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0 1021.0
HFD2_k127_3837249_1 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 1.399e-306 953.0
HFD2_k127_3837249_10 Belongs to the N(4) N(6)-methyltransferase family K00571,K00590 - 2.1.1.113,2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 465.0
HFD2_k127_3837249_11 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000605 395.0
HFD2_k127_3837249_12 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 376.0
HFD2_k127_3837249_13 Histidine kinase K07653 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 353.0
HFD2_k127_3837249_14 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 338.0
HFD2_k127_3837249_15 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 349.0
HFD2_k127_3837249_16 Transcriptional regulatory protein, C terminal K07669,K07672 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 329.0
HFD2_k127_3837249_17 Alanine racemase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 314.0
HFD2_k127_3837249_18 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 318.0
HFD2_k127_3837249_19 Protein of unknown function (DUF418) K07148 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 315.0
HFD2_k127_3837249_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 588.0
HFD2_k127_3837249_20 Neutral zinc metallopeptidase K07054 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 311.0
HFD2_k127_3837249_21 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006118 273.0
HFD2_k127_3837249_22 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002456 271.0
HFD2_k127_3837249_23 Virulence factor BrkB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001252 253.0
HFD2_k127_3837249_24 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000003912 235.0
HFD2_k127_3837249_25 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000001377 227.0
HFD2_k127_3837249_26 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001591 229.0
HFD2_k127_3837249_27 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000001091 233.0
HFD2_k127_3837249_28 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000001647 225.0
HFD2_k127_3837249_29 FMN binding - - - 0.000000000000000000000000000000000000000000000003963 181.0
HFD2_k127_3837249_3 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 561.0
HFD2_k127_3837249_30 Domain of unknown function (DUF4395) - - - 0.00000000000000000000000000000000000000000000344 171.0
HFD2_k127_3837249_31 Psort location Cytoplasmic, score K03855 - - 0.00000000000000000000000000000000000000001918 162.0
HFD2_k127_3837249_32 Domain of unknown function (DUF3291) - - - 0.000000000000000000000000000000000000005165 156.0
HFD2_k127_3837249_33 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000000006377 154.0
HFD2_k127_3837249_34 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000004179 145.0
HFD2_k127_3837249_35 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000001488 141.0
HFD2_k127_3837249_36 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000000000001904 125.0
HFD2_k127_3837249_37 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000001053 125.0
HFD2_k127_3837249_39 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000018 104.0
HFD2_k127_3837249_4 geranylgeranyl reductase activity K00313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009066 541.0
HFD2_k127_3837249_40 - - - - 0.00000000000000000000131 105.0
HFD2_k127_3837249_41 helix_turn_helix, cAMP Regulatory protein - - - 0.000000000000000000001731 102.0
HFD2_k127_3837249_42 DNA-templated transcription, initiation K03088 - - 0.000000000000000464 88.0
HFD2_k127_3837249_43 -acetyltransferase K03829 - - 0.0000005852 60.0
HFD2_k127_3837249_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 509.0
HFD2_k127_3837249_6 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 509.0
HFD2_k127_3837249_7 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 504.0
HFD2_k127_3837249_8 non-haem dioxygenase in morphine synthesis N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 472.0
HFD2_k127_3837249_9 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K17883 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0010126,GO:0016137,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050627,GO:0050660,GO:0050661,GO:0050662,GO:0051186,GO:0055114,GO:0070402,GO:0071704,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901657 1.8.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 479.0
HFD2_k127_3904346_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 2719.0
HFD2_k127_3904346_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 9.77e-208 653.0
HFD2_k127_3904346_10 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000001338 173.0
HFD2_k127_3904346_11 CGNR zinc finger - - - 0.000000000000000000000000000002899 129.0
HFD2_k127_3904346_12 GYD domain - - - 0.00000003934 63.0
HFD2_k127_3904346_2 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 437.0
HFD2_k127_3904346_3 Trypsin-like serine protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 426.0
HFD2_k127_3904346_4 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 324.0
HFD2_k127_3904346_5 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002133 258.0
HFD2_k127_3904346_6 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003739 248.0
HFD2_k127_3904346_7 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000007771 225.0
HFD2_k127_3904346_8 Nuclease-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000004535 220.0
HFD2_k127_3904346_9 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000000002232 211.0
HFD2_k127_3955762_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 9.502e-217 691.0
HFD2_k127_3955762_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.552e-206 671.0
HFD2_k127_3955762_10 beta-keto acid cleavage enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 462.0
HFD2_k127_3955762_11 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006467 451.0
HFD2_k127_3955762_12 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 455.0
HFD2_k127_3955762_13 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007496 457.0
HFD2_k127_3955762_14 unsaturated fatty acid biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 440.0
HFD2_k127_3955762_15 Zn-dependent oxidoreductase, NADPH quinone reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 413.0
HFD2_k127_3955762_16 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008789 412.0
HFD2_k127_3955762_17 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009099 400.0
HFD2_k127_3955762_18 Daunorubicin resistance ABC transporter ATP-binding subunit K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 383.0
HFD2_k127_3955762_19 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 374.0
HFD2_k127_3955762_2 Peptidase dimerisation domain - - - 2.822e-201 638.0
HFD2_k127_3955762_20 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 360.0
HFD2_k127_3955762_21 ABC-type dipeptide transport system K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009398 359.0
HFD2_k127_3955762_22 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 322.0
HFD2_k127_3955762_23 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 319.0
HFD2_k127_3955762_24 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 316.0
HFD2_k127_3955762_25 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 311.0
HFD2_k127_3955762_26 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 313.0
HFD2_k127_3955762_27 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 311.0
HFD2_k127_3955762_28 Peptidase family M48 K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 309.0
HFD2_k127_3955762_29 Esterase K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007911 282.0
HFD2_k127_3955762_3 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 592.0
HFD2_k127_3955762_30 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001167 295.0
HFD2_k127_3955762_31 isochorismatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001637 276.0
HFD2_k127_3955762_32 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000054 284.0
HFD2_k127_3955762_33 Sterol carrier protein domain - GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008080,GO:0008150,GO:0008152,GO:0009056,GO:0009605,GO:0009607,GO:0009987,GO:0010941,GO:0016137,GO:0016139,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017001,GO:0017144,GO:0030647,GO:0030649,GO:0031347,GO:0031349,GO:0032101,GO:0032103,GO:0034069,GO:0035821,GO:0040007,GO:0042802,GO:0043067,GO:0043207,GO:0044003,GO:0044068,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044248,GO:0044403,GO:0044419,GO:0044531,GO:0048518,GO:0048583,GO:0048584,GO:0050727,GO:0050729,GO:0050789,GO:0050794,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052032,GO:0052035,GO:0052040,GO:0052164,GO:0052167,GO:0052173,GO:0052200,GO:0052248,GO:0052255,GO:0052256,GO:0052259,GO:0052303,GO:0052306,GO:0052509,GO:0052510,GO:0052550,GO:0052552,GO:0052553,GO:0052564,GO:0052567,GO:0052572,GO:0065007,GO:0071704,GO:0075136,GO:0080134,GO:1901135,GO:1901136,GO:1901575,GO:1901657,GO:1901658 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002728 278.0
HFD2_k127_3955762_34 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002616 261.0
HFD2_k127_3955762_35 Enoyl-CoA hydratase/isomerase K08299 - 4.2.1.149 0.00000000000000000000000000000000000000000000000000000000000000000000000007843 264.0
HFD2_k127_3955762_36 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000007588 239.0
HFD2_k127_3955762_37 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000001718 238.0
HFD2_k127_3955762_38 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000005298 235.0
HFD2_k127_3955762_39 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.00000000000000000000000000000000000000000000000004357 182.0
HFD2_k127_3955762_4 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 584.0
HFD2_k127_3955762_40 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K17735 - 1.1.1.108 0.000000000000000000000000000000000000000000000002357 190.0
HFD2_k127_3955762_41 4fe-4S ferredoxin, iron-sulfur binding domain protein K03616 - - 0.0000000000000000000000000000000000000000000012 181.0
HFD2_k127_3955762_42 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000005639 179.0
HFD2_k127_3955762_43 YjbR - - - 0.000000000000000000000000000000000000000001103 159.0
HFD2_k127_3955762_44 YCII-related domain - - - 0.00000000000000000000000000000000000001299 151.0
HFD2_k127_3955762_45 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000002259 135.0
HFD2_k127_3955762_46 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.000000000000000000000000001538 124.0
HFD2_k127_3955762_47 Universal stress protein - - - 0.00000000000000000000000003409 115.0
HFD2_k127_3955762_48 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000005868 111.0
HFD2_k127_3955762_49 ABC-2 family transporter protein K01992 - - 0.000000000000007023 86.0
HFD2_k127_3955762_5 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 577.0
HFD2_k127_3955762_6 COG1042 Acyl-CoA synthetase (NDP forming) K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 547.0
HFD2_k127_3955762_7 acyl-CoA dehydrogenase K00248,K00249 - 1.3.8.1,1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 530.0
HFD2_k127_3955762_8 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 516.0
HFD2_k127_3955762_9 AMP-binding enzyme C-terminal domain K02182 - 6.2.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 518.0
HFD2_k127_401551_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 302.0
HFD2_k127_401551_1 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000001076 248.0
HFD2_k127_401551_2 Protein of unknown function (DUF998) - - - 0.00000000000000000000000000000000000000005842 161.0
HFD2_k127_401551_3 - - - - 0.0000000000000000000000000000000000002045 145.0
HFD2_k127_401551_4 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000000001309 131.0
HFD2_k127_401551_5 - K01992 - - 0.000000000000000144 89.0
HFD2_k127_401551_6 FR47-like protein - - - 0.00000001455 66.0
HFD2_k127_4054118_0 AMP-binding enzyme C-terminal domain - - - 2.742e-268 832.0
HFD2_k127_4054118_1 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 1.939e-251 802.0
HFD2_k127_4054118_10 C-terminal domain of 1-Cys peroxiredoxin - - - 0.000000003032 63.0
HFD2_k127_4054118_2 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 423.0
HFD2_k127_4054118_3 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000000000000000000000000000001779 208.0
HFD2_k127_4054118_4 Cupin domain K08641,K11312 - 3.4.13.22 0.000000000000000000000000000000000000000000000007251 177.0
HFD2_k127_4054118_5 DinB superfamily - - - 0.00000000000000000000000000000000000000000000002149 179.0
HFD2_k127_4054118_6 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.0000000000000000000000000000000000000000000136 169.0
HFD2_k127_4054118_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000004832 153.0
HFD2_k127_4054118_8 - - - - 0.000000000000000000000000000000003533 134.0
HFD2_k127_4054118_9 Transcriptional regulator - - - 0.00000000000000000000000009201 109.0
HFD2_k127_4079197_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 569.0
HFD2_k127_4079197_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000003897 222.0
HFD2_k127_4079197_2 MafB19-like deaminase K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000001001 209.0
HFD2_k127_4171812_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 1.41e-226 717.0
HFD2_k127_4171812_1 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 2.376e-196 619.0
HFD2_k127_4171812_2 AAA domain K07028 GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009987,GO:0030312,GO:0044464,GO:0044764,GO:0046812,GO:0051704,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 409.0
HFD2_k127_4171812_3 beta-1,4-mannooligosaccharide phosphorylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007543 393.0
HFD2_k127_4171812_4 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000001228 233.0
HFD2_k127_4171812_5 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000001564 175.0
HFD2_k127_4171812_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000001289 123.0
HFD2_k127_4171812_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000004758 102.0
HFD2_k127_4171812_8 Nitroreductase family - - - 0.00000000008938 66.0
HFD2_k127_4171812_9 transferase activity, transferring glycosyl groups - - - 0.0003507 45.0
HFD2_k127_4438532_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 9.324e-195 636.0
HFD2_k127_4438532_1 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 360.0
HFD2_k127_4438532_10 Protein of unknown function with PCYCGC motif - - - 0.0000000002719 68.0
HFD2_k127_4438532_2 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 319.0
HFD2_k127_4438532_3 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 311.0
HFD2_k127_4438532_4 His Kinase A (phosphoacceptor) domain K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001143 287.0
HFD2_k127_4438532_5 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006377 270.0
HFD2_k127_4438532_6 PFAM response regulator receiver K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000003123 237.0
HFD2_k127_4438532_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000002486 165.0
HFD2_k127_4438532_8 - - - - 0.000000000000000000000000007347 115.0
HFD2_k127_4438532_9 Protein of unknown function (DUF4243) - - - 0.00000000000000006767 92.0
HFD2_k127_4448504_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1586.0
HFD2_k127_4448504_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1088.0
HFD2_k127_4448504_10 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 400.0
HFD2_k127_4448504_11 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 364.0
HFD2_k127_4448504_12 Carbon-nitrogen hydrolase K01501 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 367.0
HFD2_k127_4448504_13 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 355.0
HFD2_k127_4448504_14 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 355.0
HFD2_k127_4448504_15 hydratase K01617,K02509 - 4.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 325.0
HFD2_k127_4448504_16 COG1062 Zn-dependent alcohol dehydrogenases, class III K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 321.0
HFD2_k127_4448504_17 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 294.0
HFD2_k127_4448504_18 Rieske [2Fe-2S] domain K22325 - 1.14.15.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009581 287.0
HFD2_k127_4448504_19 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007238 264.0
HFD2_k127_4448504_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.35e-321 994.0
HFD2_k127_4448504_20 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003921 257.0
HFD2_k127_4448504_21 protocatechuate 3,4-dioxygenase, beta subunit' K03381 - 1.13.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000005063 252.0
HFD2_k127_4448504_22 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000471 239.0
HFD2_k127_4448504_23 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000008371 222.0
HFD2_k127_4448504_24 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000003109 194.0
HFD2_k127_4448504_25 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000001408 195.0
HFD2_k127_4448504_26 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000001658 179.0
HFD2_k127_4448504_27 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000005685 189.0
HFD2_k127_4448504_28 Phosphotransferase K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000002139 179.0
HFD2_k127_4448504_29 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000001856 175.0
HFD2_k127_4448504_3 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 558.0
HFD2_k127_4448504_30 proteolysis K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000006885 169.0
HFD2_k127_4448504_31 PFAM Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000001533 164.0
HFD2_k127_4448504_32 TIGRFAM deazaflavin-dependent nitroreductase family protein - - - 0.0000000000000000000000000000000000000000622 162.0
HFD2_k127_4448504_33 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000006456 155.0
HFD2_k127_4448504_34 Drug resistance transporter, bcr cfla subfamily K07552 - - 0.00000000000000000000000000000000001685 150.0
HFD2_k127_4448504_35 Haem-degrading - - - 0.0000000000000000000000000000000002311 145.0
HFD2_k127_4448504_36 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000293 118.0
HFD2_k127_4448504_37 Drug resistance transporter, bcr cfla subfamily K07552 - - 0.00000000000000000003635 102.0
HFD2_k127_4448504_38 phosphatase activity K07025 - - 0.00000004182 64.0
HFD2_k127_4448504_4 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483 - 1.14.14.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 551.0
HFD2_k127_4448504_5 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 542.0
HFD2_k127_4448504_6 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009016 518.0
HFD2_k127_4448504_7 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 462.0
HFD2_k127_4448504_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004941 432.0
HFD2_k127_4448504_9 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 404.0
HFD2_k127_4457901_0 diacylglycerol O-acyltransferase K00635 GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700 2.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 533.0
HFD2_k127_4457901_1 acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 496.0
HFD2_k127_4457901_10 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004505 276.0
HFD2_k127_4457901_11 tRNA processing K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005762 258.0
HFD2_k127_4457901_12 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000003581 235.0
HFD2_k127_4457901_13 Copper resistance protein CopC K14166 - - 0.00000000000000000000000000000000000000000000000000000000003389 231.0
HFD2_k127_4457901_14 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000166 208.0
HFD2_k127_4457901_15 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000003623 178.0
HFD2_k127_4457901_16 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000006687 173.0
HFD2_k127_4457901_17 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000002037 164.0
HFD2_k127_4457901_18 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000001407 160.0
HFD2_k127_4457901_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 482.0
HFD2_k127_4457901_20 Domain of unkown function (DUF1775) - - - 0.0000000000000000007449 95.0
HFD2_k127_4457901_21 - - - - 0.000000000000000001999 96.0
HFD2_k127_4457901_22 Putative zinc-finger K03088 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000003379 71.0
HFD2_k127_4457901_25 - - - - 0.0008862 50.0
HFD2_k127_4457901_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 406.0
HFD2_k127_4457901_4 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 392.0
HFD2_k127_4457901_5 transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008778 343.0
HFD2_k127_4457901_6 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 355.0
HFD2_k127_4457901_7 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 346.0
HFD2_k127_4457901_8 PD-(D/E)XK nuclease superfamily K07465 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 328.0
HFD2_k127_4457901_9 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 326.0
HFD2_k127_4493632_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 508.0
HFD2_k127_4493632_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 445.0
HFD2_k127_4493632_3 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 303.0
HFD2_k127_4493632_4 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004436 297.0
HFD2_k127_4493632_5 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000004605 242.0
HFD2_k127_4493632_6 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000001687 240.0
HFD2_k127_4493632_7 Phosphotransferase enzyme family - - - 0.0000000000000000003898 98.0
HFD2_k127_4493632_8 - - - - 0.000000000005079 68.0
HFD2_k127_4521856_0 Pyridoxal-phosphate dependent enzyme K01505,K05396 - 3.5.99.7,4.4.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 543.0
HFD2_k127_4521856_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008851 316.0
HFD2_k127_4521856_2 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001738 269.0
HFD2_k127_4521856_3 Pfam Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001756 262.0
HFD2_k127_4521856_4 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000421 107.0
HFD2_k127_4521856_5 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000003607 75.0
HFD2_k127_4521856_6 PFAM Sporulation and spore germination - - - 0.0000000000068 76.0
HFD2_k127_4524063_0 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2336.0
HFD2_k127_4524063_1 Fibronectin type iii domain protein - - - 0.0 1508.0
HFD2_k127_4524063_10 Mur ligase family, glutamate ligase domain K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 445.0
HFD2_k127_4524063_11 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009917 390.0
HFD2_k127_4524063_12 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 401.0
HFD2_k127_4524063_13 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 394.0
HFD2_k127_4524063_14 Thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 327.0
HFD2_k127_4524063_15 PFAM Alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 304.0
HFD2_k127_4524063_16 transcriptional regulator K09017 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007705 251.0
HFD2_k127_4524063_17 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000054 240.0
HFD2_k127_4524063_18 Putative FMN-binding domain K07734 - - 0.0000000000000000000000000000000000000000000000000000000005029 208.0
HFD2_k127_4524063_19 AsnC family transcriptional regulator K03719 - - 0.0000000000000000000000000000000000000000000000000001062 191.0
HFD2_k127_4524063_2 haloacid dehalogenase-like hydrolase - - - 0.0 1127.0
HFD2_k127_4524063_20 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000000000000000000007591 186.0
HFD2_k127_4524063_21 Belongs to the UPF0502 family K09915 - - 0.0000000000000000000000000000000000000000000002017 174.0
HFD2_k127_4524063_22 LysM domain - - - 0.000000000000000000392 101.0
HFD2_k127_4524063_23 Phosphoribosyl transferase domain K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000009922 68.0
HFD2_k127_4524063_3 Domain of unknown function (DUF2088) - - - 7.005e-286 885.0
HFD2_k127_4524063_4 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 8.934e-265 820.0
HFD2_k127_4524063_5 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 2.152e-234 733.0
HFD2_k127_4524063_6 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 557.0
HFD2_k127_4524063_7 cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000624 524.0
HFD2_k127_4524063_8 DNA ligase N terminus K10747 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 507.0
HFD2_k127_4524063_9 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 433.0
HFD2_k127_4566223_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1400.0
HFD2_k127_4566223_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 2.042e-246 773.0
HFD2_k127_4566223_2 membrane protein terC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 404.0
HFD2_k127_4566223_3 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004803 273.0
HFD2_k127_4566223_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000773 60.0
HFD2_k127_4619454_0 Multicopper oxidase - - - 6.352e-306 955.0
HFD2_k127_4619454_1 alpha-galactosidase K07407 - 3.2.1.22 1.44e-304 950.0
HFD2_k127_4619454_10 PFAM regulatory protein ArsR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 379.0
HFD2_k127_4619454_11 Zinc-binding dehydrogenase K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 338.0
HFD2_k127_4619454_12 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008514 327.0
HFD2_k127_4619454_13 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 318.0
HFD2_k127_4619454_14 Methylenetetrahydrofolate reductase K00297 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 295.0
HFD2_k127_4619454_15 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 310.0
HFD2_k127_4619454_16 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001966 277.0
HFD2_k127_4619454_17 Binding-protein-dependent transport system inner membrane component K02025,K10118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001771 267.0
HFD2_k127_4619454_18 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002108 253.0
HFD2_k127_4619454_19 reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000008919 237.0
HFD2_k127_4619454_2 Belongs to the aldehyde dehydrogenase family K00151 - 1.2.1.60 6.862e-226 709.0
HFD2_k127_4619454_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002029 249.0
HFD2_k127_4619454_21 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.0000000000000000000000000000000000000000000000000000000001451 206.0
HFD2_k127_4619454_22 DoxX K15977 - - 0.0000000000000000000000000000000000000000000000000000006107 199.0
HFD2_k127_4619454_23 YjbR - - - 0.0000000000000000000000000000000000000000000000000001491 189.0
HFD2_k127_4619454_24 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000001335 177.0
HFD2_k127_4619454_25 Transglycosylase associated protein - - - 0.0000000000000000000000000000009036 125.0
HFD2_k127_4619454_26 gntR family - - - 0.000000000000000000000000000004574 123.0
HFD2_k127_4619454_27 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000004631 121.0
HFD2_k127_4619454_28 PAP2 superfamily - - - 0.000000000000000000000000265 116.0
HFD2_k127_4619454_29 Bacterial lipid A biosynthesis acyltransferase K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.265 0.00000000001412 76.0
HFD2_k127_4619454_3 Belongs to the thiolase family - - - 5.874e-216 675.0
HFD2_k127_4619454_30 - - - - 0.0000000001828 65.0
HFD2_k127_4619454_31 Methylmuconolactone methyl-isomerase - - - 0.00000000493 66.0
HFD2_k127_4619454_32 Methylmuconolactone methyl-isomerase - - - 0.0000002273 58.0
HFD2_k127_4619454_34 - - - - 0.0005558 48.0
HFD2_k127_4619454_4 AMP-binding enzyme C-terminal domain K18661 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007379 544.0
HFD2_k127_4619454_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 459.0
HFD2_k127_4619454_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 461.0
HFD2_k127_4619454_7 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 414.0
HFD2_k127_4619454_8 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 414.0
HFD2_k127_4619454_9 2-dehydropantoate 2-reductase K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 385.0
HFD2_k127_4656783_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1774.0
HFD2_k127_4656783_1 ThiF family - - - 3.001e-205 647.0
HFD2_k127_4656783_10 PFAM pfkB family carbohydrate kinase K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006355 331.0
HFD2_k127_4656783_11 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006551 348.0
HFD2_k127_4656783_12 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 300.0
HFD2_k127_4656783_13 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002684 285.0
HFD2_k127_4656783_14 myo-inosose-2 dehydratase activity K03335 - 4.2.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000328 273.0
HFD2_k127_4656783_16 - - - - 0.0000000000000000000000000000000000000000000000000000009977 200.0
HFD2_k127_4656783_17 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000004151 190.0
HFD2_k127_4656783_18 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000001244 182.0
HFD2_k127_4656783_19 nUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000188 170.0
HFD2_k127_4656783_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K03520 - 1.2.5.3 1.075e-204 664.0
HFD2_k127_4656783_20 arsenate reductase (glutaredoxin) activity K00537 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 0.0000000000000000000000000000000003502 133.0
HFD2_k127_4656783_21 Binding-protein-dependent transport system inner membrane component K10233 - - 0.000000000000000000000000000000001532 137.0
HFD2_k127_4656783_23 Transglycosylase associated protein - - - 0.0000000000000000000000000000001459 125.0
HFD2_k127_4656783_24 Protein of unknown function (DUF4031) - - - 0.0000000000000000000000000000006673 124.0
HFD2_k127_4656783_25 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000001489 100.0
HFD2_k127_4656783_26 Rieske 2Fe-2S - - - 0.000000000000000000005146 98.0
HFD2_k127_4656783_27 SnoaL-like domain - - - 0.00000000000000000197 97.0
HFD2_k127_4656783_29 Glucose / Sorbosone dehydrogenase K21430 - - 0.0001693 52.0
HFD2_k127_4656783_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 575.0
HFD2_k127_4656783_30 transcriptional regulator, TetR family - - - 0.0005491 44.0
HFD2_k127_4656783_4 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 516.0
HFD2_k127_4656783_5 CobW/HypB/UreG, nucleotide-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 497.0
HFD2_k127_4656783_6 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 506.0
HFD2_k127_4656783_7 ATPases associated with a variety of cellular activities K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 443.0
HFD2_k127_4656783_8 Bacterial extracellular solute-binding protein K10232 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 379.0
HFD2_k127_4656783_9 Sir2 family K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 355.0
HFD2_k127_4727539_0 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 GO:0000287,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0016054,GO:0016740,GO:0016746,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0046395,GO:0046487,GO:0046872,GO:0046912,GO:0071704,GO:0072329,GO:1901575 2.3.3.9 2.005e-301 955.0
HFD2_k127_4727539_1 Aminotransferase class-V - - - 7.137e-277 861.0
HFD2_k127_4727539_10 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000001435 175.0
HFD2_k127_4727539_11 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000000000000001587 160.0
HFD2_k127_4727539_12 PFAM Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000002149 173.0
HFD2_k127_4727539_13 FCD - - - 0.00000000000000000000000000000000000000172 156.0
HFD2_k127_4727539_14 InterPro IPR014922 - - - 0.00000000000000000001521 96.0
HFD2_k127_4727539_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 543.0
HFD2_k127_4727539_3 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008316 301.0
HFD2_k127_4727539_4 Electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008603 271.0
HFD2_k127_4727539_5 dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001047 258.0
HFD2_k127_4727539_6 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000008599 234.0
HFD2_k127_4727539_7 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000004753 215.0
HFD2_k127_4727539_8 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000567 215.0
HFD2_k127_4727539_9 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000004281 200.0
HFD2_k127_48147_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1415.0
HFD2_k127_48147_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372,K02567 - - 0.0 1217.0
HFD2_k127_48147_10 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 531.0
HFD2_k127_48147_11 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 488.0
HFD2_k127_48147_12 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 460.0
HFD2_k127_48147_13 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 448.0
HFD2_k127_48147_14 nitrite transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 438.0
HFD2_k127_48147_15 DEAD DEAH box helicase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 445.0
HFD2_k127_48147_16 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006782 419.0
HFD2_k127_48147_17 synthase K00697,K16055 GO:0003674,GO:0003824,GO:0003825,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0030312,GO:0033554,GO:0034637,GO:0035251,GO:0040007,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046527,GO:0046872,GO:0046914,GO:0047260,GO:0050896,GO:0051716,GO:0070413,GO:0071704,GO:0071944,GO:1901576 2.4.1.15,2.4.1.347,3.1.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 436.0
HFD2_k127_48147_18 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 422.0
HFD2_k127_48147_19 ABC transporter substrate-binding protein K10543 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005975,GO:0005996,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0015749,GO:0015750,GO:0015753,GO:0019321,GO:0030246,GO:0030288,GO:0030313,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0042732,GO:0044238,GO:0044281,GO:0044464,GO:0048029,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008224 406.0
HFD2_k127_48147_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.758e-319 984.0
HFD2_k127_48147_20 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 389.0
HFD2_k127_48147_21 Protein of unknown function (DUF1298) K00635 - 2.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 410.0
HFD2_k127_48147_22 dna polymerase III delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 385.0
HFD2_k127_48147_23 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 384.0
HFD2_k127_48147_24 ComEC Rec2-related protein K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 390.0
HFD2_k127_48147_25 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 379.0
HFD2_k127_48147_26 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005618 362.0
HFD2_k127_48147_27 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 351.0
HFD2_k127_48147_28 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 339.0
HFD2_k127_48147_29 Oxidoreductase NAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 332.0
HFD2_k127_48147_3 PFAM AMP-dependent synthetase and ligase K00666,K01909 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008922,GO:0009058,GO:0009987,GO:0015645,GO:0016020,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016874,GO:0016877,GO:0016878,GO:0017076,GO:0019752,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046394,GO:0051704,GO:0070566,GO:0071704,GO:0071944,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 6.2.1.20 3.201e-273 856.0
HFD2_k127_48147_30 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007618 333.0
HFD2_k127_48147_31 PAC2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 320.0
HFD2_k127_48147_32 Tetratricopeptide repeat K05838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 312.0
HFD2_k127_48147_33 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 303.0
HFD2_k127_48147_34 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 297.0
HFD2_k127_48147_35 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006733 280.0
HFD2_k127_48147_36 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005327 278.0
HFD2_k127_48147_37 Belongs to the binding-protein-dependent transport system permease family K10544 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001565 273.0
HFD2_k127_48147_38 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002602 274.0
HFD2_k127_48147_39 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007422 274.0
HFD2_k127_48147_4 MMPL family K07003 - - 6.72e-202 665.0
HFD2_k127_48147_40 ABC-type branched-chain amino acid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005077 267.0
HFD2_k127_48147_41 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001323 256.0
HFD2_k127_48147_42 HPP family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003104 254.0
HFD2_k127_48147_43 Fatty acid desaturase K00508 - 1.14.19.3 0.000000000000000000000000000000000000000000000000000000000000000000004673 247.0
HFD2_k127_48147_44 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000001241 229.0
HFD2_k127_48147_45 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.000000000000000000000000000000000000000000000000000000000000008688 227.0
HFD2_k127_48147_46 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000001672 206.0
HFD2_k127_48147_47 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000005384 207.0
HFD2_k127_48147_48 oxidoreductase activity K07114 - - 0.00000000000000000000000000000000000000000000000000003011 206.0
HFD2_k127_48147_49 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000889 192.0
HFD2_k127_48147_5 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 621.0
HFD2_k127_48147_50 Domain of unknown function (DUF1989) K09967 - - 0.00000000000000000000000000000000000000000000000001448 186.0
HFD2_k127_48147_51 ABC-type antimicrobial peptide transport system, ATPase component K02003,K05685 - - 0.00000000000000000000000000000000000000000000005176 177.0
HFD2_k127_48147_52 Competence protein ComEA K02237 - - 0.0000000000000000000000000000000000000000000001256 177.0
HFD2_k127_48147_53 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000000000000000000000000000000000008064 162.0
HFD2_k127_48147_54 Transcriptional regulator - - - 0.0000000000000000000000000000000000000003257 161.0
HFD2_k127_48147_55 Acetyltransferase (GNAT) family K00657 - 2.3.1.57 0.000000000000000000000000000000000000008724 150.0
HFD2_k127_48147_56 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000005304 165.0
HFD2_k127_48147_57 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000002699 151.0
HFD2_k127_48147_58 cyclic nucleotide binding K10914 - - 0.0000000000000000000000000000000000004021 156.0
HFD2_k127_48147_59 PFAM Glyoxalase Bleomycin resistance protein Dioxygenase superfamily K08234 - - 0.000000000000000000000000000000000006603 142.0
HFD2_k127_48147_6 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 595.0
HFD2_k127_48147_60 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000007386 139.0
HFD2_k127_48147_61 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000006103 115.0
HFD2_k127_48147_62 Cold shock protein K03704 - - 0.00000000000000000000000199 105.0
HFD2_k127_48147_63 Major Facilitator Superfamily - - - 0.00000000000000000000005088 114.0
HFD2_k127_48147_65 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000001715 84.0
HFD2_k127_48147_66 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000003607 85.0
HFD2_k127_48147_68 - - - - 0.00000000000008649 82.0
HFD2_k127_48147_69 lipolytic protein G-D-S-L family - - - 0.00000000003239 74.0
HFD2_k127_48147_7 Rieske 2Fe-2S K00499 - 1.14.15.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 557.0
HFD2_k127_48147_70 Sucrose-6F-phosphate phosphohydrolase - - - 0.000001165 58.0
HFD2_k127_48147_71 BFD-like [2Fe-2S] binding domain K02192 - - 0.0000166 49.0
HFD2_k127_48147_72 - - - - 0.0004734 47.0
HFD2_k127_48147_8 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 567.0
HFD2_k127_48147_9 F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 535.0
HFD2_k127_4819853_0 Peroxidase K03782 - 1.11.1.21 0.0 1191.0
HFD2_k127_4819853_1 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 585.0
HFD2_k127_4819853_10 PFAM CoA-binding domain protein K06929 - - 0.00000000000000000000000000000000000000000000000000000000000000001794 226.0
HFD2_k127_4819853_11 PFAM Uracil-DNA glycosylase superfamily K03649 - 3.2.2.28 0.0000000000000000000000000000000000000000000000000000000000000000211 233.0
HFD2_k127_4819853_12 Ferric uptake regulator family K22297 - - 0.0000000000000000000000000000000000000000000000000000001147 202.0
HFD2_k127_4819853_13 May play a role in the intracellular transport of hydrophobic ligands - - - 0.000000000000000000000000000000000000000000000000000002041 203.0
HFD2_k127_4819853_14 - - - - 0.00000000000000000000000000000000000000000000000000294 192.0
HFD2_k127_4819853_15 Transcription regulator MerR, DNA binding - - - 0.0000000000000000000000000000000000000000000914 169.0
HFD2_k127_4819853_17 Transcriptional regulator ArsR family - - - 0.0000000000000000000000000000000001682 136.0
HFD2_k127_4819853_18 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000006944 142.0
HFD2_k127_4819853_19 Domain of unknown function (DUF4389) - - - 0.000000000000000000000000000008327 130.0
HFD2_k127_4819853_2 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 535.0
HFD2_k127_4819853_20 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000005396 90.0
HFD2_k127_4819853_21 - - - - 0.0000000000000001563 86.0
HFD2_k127_4819853_22 Putative sensor - - - 0.0000000000000003054 89.0
HFD2_k127_4819853_23 SnoaL-like polyketide cyclase - - - 0.000000000000005524 83.0
HFD2_k127_4819853_24 Scaffold protein Nfu/NifU N terminal - - - 0.000007758 52.0
HFD2_k127_4819853_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 442.0
HFD2_k127_4819853_4 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009317 375.0
HFD2_k127_4819853_5 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 368.0
HFD2_k127_4819853_6 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 299.0
HFD2_k127_4819853_7 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007903 285.0
HFD2_k127_4819853_8 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000022 268.0
HFD2_k127_4819853_9 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002997 247.0
HFD2_k127_4826694_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009234 428.0
HFD2_k127_4826694_1 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000864 336.0
HFD2_k127_4826694_10 - - - - 0.00004662 53.0
HFD2_k127_4826694_2 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 297.0
HFD2_k127_4826694_3 Putative peptidoglycan binding domain - - - 0.00000000000000000000000002089 126.0
HFD2_k127_4826694_4 Domain of unknown function (DUF1330) - - - 0.000000000000000000005684 95.0
HFD2_k127_4826694_5 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000006891 104.0
HFD2_k127_4826694_6 - - - - 0.0000000002526 70.0
HFD2_k127_4826694_7 FtsX-like permease family - - - 0.000000003049 67.0
HFD2_k127_4826694_8 Transcriptional regulator - - - 0.00000004277 57.0
HFD2_k127_4826694_9 - - - - 0.00000009963 63.0
HFD2_k127_4835283_0 helicase activity - - - 0.0 1039.0
HFD2_k127_4835283_1 Belongs to the cysteine synthase cystathionine beta- synthase family - - - 4.364e-256 800.0
HFD2_k127_4835283_10 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000004393 96.0
HFD2_k127_4835283_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 386.0
HFD2_k127_4835283_3 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009614 382.0
HFD2_k127_4835283_4 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009679 377.0
HFD2_k127_4835283_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000001876 250.0
HFD2_k127_4835283_6 Conserved hypothetical protein (DUF2461) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009205 247.0
HFD2_k127_4835283_7 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000009276 188.0
HFD2_k127_4835283_8 PFAM Helix-turn-helix, type 11 domain protein - - - 0.0000000000000000000000000000000000000000000000005455 182.0
HFD2_k127_4835283_9 EamA-like transporter family - - - 0.000000000000000000000000000007048 128.0
HFD2_k127_491421_0 Belongs to the carbamoyltransferase HypF family K04656 - - 2.287e-226 724.0
HFD2_k127_491421_1 arsenical-resistance protein K03325,K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 536.0
HFD2_k127_491421_10 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03325,K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000003849 188.0
HFD2_k127_491421_11 Low molecular weight phosphatase family K03741,K18701 - 1.20.4.1,2.8.4.2 0.0000000000000000000000000000000000000000000000000004162 195.0
HFD2_k127_491421_12 glyoxalase bleomycin resistance protein dioxygenase - GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896 - 0.00000000000000000000000000000000000000000003275 166.0
HFD2_k127_491421_13 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000004395 148.0
HFD2_k127_491421_14 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000009926 126.0
HFD2_k127_491421_15 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.0000000000000000000000003116 108.0
HFD2_k127_491421_16 ABC transporter ATP-binding K01990 - - 0.0000000000000001119 80.0
HFD2_k127_491421_17 NfeD-like C-terminal, partner-binding - - - 0.000003688 59.0
HFD2_k127_491421_2 AIR synthase related protein, C-terminal domain K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 512.0
HFD2_k127_491421_3 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 307.0
HFD2_k127_491421_4 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 289.0
HFD2_k127_491421_5 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000000000000000000000000000000000000000001026 257.0
HFD2_k127_491421_6 Belongs to the MIP aquaporin (TC 1.A.8) family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000006893 263.0
HFD2_k127_491421_7 HupF/HypC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002357 243.0
HFD2_k127_491421_8 phosphoheptose isomerase K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000377 226.0
HFD2_k127_491421_9 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000006912 220.0
HFD2_k127_4972995_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.0 1221.0
HFD2_k127_4972995_1 Putative carbohydrate binding domain K00702 - 2.4.1.20 0.0 1185.0
HFD2_k127_4972995_10 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 334.0
HFD2_k127_4972995_11 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002906 286.0
HFD2_k127_4972995_12 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001805 286.0
HFD2_k127_4972995_13 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001564 279.0
HFD2_k127_4972995_14 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002417 258.0
HFD2_k127_4972995_15 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002457 261.0
HFD2_k127_4972995_16 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002105 268.0
HFD2_k127_4972995_17 hydratase K02509 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001884 250.0
HFD2_k127_4972995_18 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000003368 222.0
HFD2_k127_4972995_19 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000005418 214.0
HFD2_k127_4972995_2 Glycogen debranching enzyme N terminal - - - 5.427e-224 716.0
HFD2_k127_4972995_20 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000002068 200.0
HFD2_k127_4972995_21 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000001584 183.0
HFD2_k127_4972995_22 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000008929 187.0
HFD2_k127_4972995_23 Redoxin - - - 0.000000000000000000000000000000000000004087 154.0
HFD2_k127_4972995_24 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000005758 148.0
HFD2_k127_4972995_25 cyclic nucleotide binding K07001,K10914 - - 0.00000000000000000000000000000000008495 141.0
HFD2_k127_4972995_26 DinB superfamily - - - 0.0000000000000000000000000000000005881 138.0
HFD2_k127_4972995_27 PFAM Disulfide bond formation protein DsbB K03611 - - 0.0000000000000000000000000000000009026 137.0
HFD2_k127_4972995_28 - - - - 0.0000000000000000000000000000009154 124.0
HFD2_k127_4972995_29 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000001351 124.0
HFD2_k127_4972995_3 GMC oxidoreductase - - - 2.331e-217 694.0
HFD2_k127_4972995_30 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000008044 113.0
HFD2_k127_4972995_31 Protein of unknown function (DUF2510) - - - 0.00000000000000004569 90.0
HFD2_k127_4972995_33 Putative zinc-finger - - - 0.00000000000002608 79.0
HFD2_k127_4972995_34 Cyclic nucleotide-binding domain - - - 0.000000000004377 75.0
HFD2_k127_4972995_35 lipolytic protein G-D-S-L family K01183 - 3.2.1.14 0.0000000002324 70.0
HFD2_k127_4972995_36 Putative zinc-finger - - - 0.0000000003442 63.0
HFD2_k127_4972995_37 procollagen-lysine 5-dioxygenase activity K00473,K13645,K13646,K13647,K15174 GO:0000003,GO:0000902,GO:0000904,GO:0001666,GO:0001701,GO:0001885,GO:0001886,GO:0002009,GO:0002064,GO:0003006,GO:0003008,GO:0003013,GO:0003018,GO:0003158,GO:0003382,GO:0003674,GO:0003824,GO:0003980,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005791,GO:0005794,GO:0005802,GO:0006011,GO:0006082,GO:0006139,GO:0006464,GO:0006486,GO:0006493,GO:0006520,GO:0006575,GO:0006725,GO:0006793,GO:0006807,GO:0006950,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007295,GO:0007399,GO:0008015,GO:0008104,GO:0008150,GO:0008152,GO:0008194,GO:0008198,GO:0008378,GO:0008475,GO:0008544,GO:0008652,GO:0009058,GO:0009059,GO:0009066,GO:0009067,GO:0009100,GO:0009101,GO:0009225,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009987,GO:0010033,GO:0012505,GO:0016020,GO:0016043,GO:0016053,GO:0016491,GO:0016705,GO:0016706,GO:0016740,GO:0016757,GO:0016758,GO:0017185,GO:0018126,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0019842,GO:0019953,GO:0021915,GO:0022412,GO:0022414,GO:0022607,GO:0030154,GO:0030198,GO:0030199,GO:0030246,GO:0030323,GO:0030324,GO:0030855,GO:0030867,GO:0031012,GO:0031090,GO:0031406,GO:0031418,GO:0031984,GO:0032501,GO:0032502,GO:0032504,GO:0032870,GO:0032963,GO:0032964,GO:0032989,GO:0032991,GO:0033036,GO:0033218,GO:0033823,GO:0034641,GO:0034645,GO:0035150,GO:0035250,GO:0035251,GO:0035295,GO:0035296,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042175,GO:0042221,GO:0042277,GO:0042311,GO:0042398,GO:0042802,GO:0042803,GO:0043009,GO:0043062,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043413,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045446,GO:0046394,GO:0046483,GO:0046527,GO:0046872,GO:0046914,GO:0046946,GO:0046947,GO:0046983,GO:0048029,GO:0048037,GO:0048468,GO:0048471,GO:0048477,GO:0048513,GO:0048589,GO:0048609,GO:0048729,GO:0048730,GO:0048731,GO:0048856,GO:0048869,GO:0050211,GO:0050662,GO:0050880,GO:0050896,GO:0051179,GO:0051213,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060425,GO:0060429,GO:0060541,GO:0062023,GO:0065007,GO:0065008,GO:0070085,GO:0070482,GO:0070815,GO:0070831,GO:0070887,GO:0071310,GO:0071495,GO:0071704,GO:0071711,GO:0071840,GO:0090066,GO:0097359,GO:0097435,GO:0097746,GO:0097755,GO:0098588,GO:0098791,GO:0098827,GO:0140096,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 1.14.11.4,2.4.1.50,2.4.1.66 0.000003531 57.0
HFD2_k127_4972995_38 - - - - 0.0002764 51.0
HFD2_k127_4972995_4 Rieske 2Fe-2S K14952 - - 4.401e-216 683.0
HFD2_k127_4972995_5 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 540.0
HFD2_k127_4972995_6 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 455.0
HFD2_k127_4972995_7 Enoyl-(Acyl carrier protein) reductase K00034 - 1.1.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 392.0
HFD2_k127_4972995_9 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 334.0
HFD2_k127_5029269_0 Belongs to the binding-protein-dependent transport system permease family K06020 - 3.6.3.25 1.005e-262 839.0
HFD2_k127_5029269_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 595.0
HFD2_k127_5029269_2 PFAM ABC transporter - - - 0.0000000000000000000008156 97.0
HFD2_k127_5085515_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006166 297.0
HFD2_k127_5085515_1 Trehalose utilisation - - - 0.000000000000000000000000000000000000004087 168.0
HFD2_k127_5085515_2 - - - - 0.00000000000000000000000000000000000008229 149.0
HFD2_k127_5085515_3 ANTAR domain protein - - - 0.00000000000000000000000000000003338 129.0
HFD2_k127_5148626_0 hydrolase, family 65, central catalytic K05342 - 2.4.1.64 2.392e-253 812.0
HFD2_k127_5148626_1 Transketolase, pyrimidine binding domain K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 507.0
HFD2_k127_5148626_10 transcriptional regulator K10947 - - 0.0000000000000000000000000065 114.0
HFD2_k127_5148626_11 PFAM Biotin lipoyl attachment - - - 0.0000000000000000000008003 100.0
HFD2_k127_5148626_12 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000006554 87.0
HFD2_k127_5148626_13 - - - - 0.000004882 55.0
HFD2_k127_5148626_2 galactose oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 502.0
HFD2_k127_5148626_3 PFAM Dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 465.0
HFD2_k127_5148626_4 Putative serine esterase (DUF676) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 353.0
HFD2_k127_5148626_5 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 287.0
HFD2_k127_5148626_6 hydrolase, family 65, central catalytic K10231 - 2.4.1.230 0.0000000000000000000000000000000000000000000000000000000000000000000002034 256.0
HFD2_k127_5148626_7 ATP-NAD kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003077 252.0
HFD2_k127_5148626_8 Domain of unknown function (DUF4188) - - - 0.00000000000000000000000000000000000000000000000000000000000000000005032 238.0
HFD2_k127_5148626_9 NIPSNAP - - - 0.000000000000000000000000000000000000000000000000002806 192.0
HFD2_k127_5151440_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 7.629e-290 896.0
HFD2_k127_5151440_1 PFAM deoxyribose-phosphate aldolase phospho-2- dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 537.0
HFD2_k127_5151440_10 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000006128 191.0
HFD2_k127_5151440_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000005289 193.0
HFD2_k127_5151440_12 AI-2E family transporter - - - 0.00000000000000000000000000000000000004102 164.0
HFD2_k127_5151440_14 haloacid dehalogenase K07025 - - 0.000000000000000000000000000000003391 137.0
HFD2_k127_5151440_16 Unextendable partial coding region - - - 0.0000000000000009529 77.0
HFD2_k127_5151440_17 - - - - 0.000000000000007347 86.0
HFD2_k127_5151440_19 Single-stranded DNA-binding protein K03111 - - 0.000001099 55.0
HFD2_k127_5151440_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 540.0
HFD2_k127_5151440_3 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 453.0
HFD2_k127_5151440_4 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 405.0
HFD2_k127_5151440_5 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 337.0
HFD2_k127_5151440_6 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003539 284.0
HFD2_k127_5151440_7 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000878 249.0
HFD2_k127_5151440_8 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000006771 211.0
HFD2_k127_5151440_9 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000007019 202.0
HFD2_k127_5175890_0 MOSC N-terminal beta barrel domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 550.0
HFD2_k127_5175890_1 Phage integrase, N-terminal SAM-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 439.0
HFD2_k127_5175890_10 Transposase, Mutator family K07493 - - 0.000000000001252 69.0
HFD2_k127_5175890_11 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000001811 66.0
HFD2_k127_5175890_12 - - - - 0.00000000001935 68.0
HFD2_k127_5175890_14 transcriptional regulator - - - 0.000000651 63.0
HFD2_k127_5175890_15 flavoprotein involved in K transport - - - 0.00001397 57.0
HFD2_k127_5175890_2 Transposase K07493 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008251 291.0
HFD2_k127_5175890_3 Transposase IS116 IS110 IS902 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002555 255.0
HFD2_k127_5175890_4 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000003412 200.0
HFD2_k127_5175890_6 Transposase IS116/IS110/IS902 family - - - 0.000000000000000000000000000000000000000000003523 177.0
HFD2_k127_5175890_7 AAA ATPase domain - - - 0.000000000000000000000000000000000008094 158.0
HFD2_k127_5175890_8 KR domain K00059 - 1.1.1.100 0.000000000000000000000001317 113.0
HFD2_k127_5175890_9 Transposase K07493 - - 0.000000000000000000000003942 102.0
HFD2_k127_5195835_0 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 484.0
HFD2_k127_5195835_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 452.0
HFD2_k127_5195835_2 Prephenate dehydrogenase K00210,K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 434.0
HFD2_k127_5195835_3 RNA pseudouridylate synthase K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 359.0
HFD2_k127_5195835_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 345.0
HFD2_k127_5195835_5 UbiA prenyltransferase family K14136 - 2.4.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 319.0
HFD2_k127_5195835_6 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 292.0
HFD2_k127_5195835_7 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001739 258.0
HFD2_k127_5195835_8 haloacid dehalogenase-like hydrolase K18697 - 3.1.3.27 0.000000000000000000000000000000000000000000000001067 182.0
HFD2_k127_5195835_9 Acyltransferase - - - 0.0000000000000000000000000001245 131.0
HFD2_k127_522141_0 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 589.0
HFD2_k127_522141_1 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 533.0
HFD2_k127_522141_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008492 442.0
HFD2_k127_522141_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 433.0
HFD2_k127_522141_4 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007641 410.0
HFD2_k127_522141_5 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 373.0
HFD2_k127_522141_6 Belongs to the UPF0301 (AlgH) family K07735 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000001725 224.0
HFD2_k127_522141_7 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000000000000000000000000000000000000000001038 211.0
HFD2_k127_522141_8 Methylpurine-DNA glycosylase (MPG) K03652 - 3.2.2.21 0.0000000000000000000000000000000000000006716 161.0
HFD2_k127_5405688_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 1.904e-263 817.0
HFD2_k127_5405688_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 3.155e-259 812.0
HFD2_k127_5405688_10 Carbon-nitrogen hydrolase K01431 - 3.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 498.0
HFD2_k127_5405688_11 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 469.0
HFD2_k127_5405688_12 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 386.0
HFD2_k127_5405688_13 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 394.0
HFD2_k127_5405688_14 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 377.0
HFD2_k127_5405688_15 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 293.0
HFD2_k127_5405688_16 phosphatase activity K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007177 287.0
HFD2_k127_5405688_17 inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004132 264.0
HFD2_k127_5405688_19 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000006191 235.0
HFD2_k127_5405688_2 Acyl-CoA dehydrogenase, C-terminal domain K14448 - 1.3.8.12 9.636e-248 775.0
HFD2_k127_5405688_20 Initiation factor 2 subunit family - - - 0.000000000000000000000000000000000000000000000000000000003468 209.0
HFD2_k127_5405688_21 - - - - 0.000000000000000000000000000000000000000000000000000000006986 203.0
HFD2_k127_5405688_22 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000000002141 205.0
HFD2_k127_5405688_23 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000006322 209.0
HFD2_k127_5405688_24 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000002484 196.0
HFD2_k127_5405688_25 nucleotidyltransferase activity - - - 0.00000000000000000000000000000000000000000003565 172.0
HFD2_k127_5405688_26 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000005337 159.0
HFD2_k127_5405688_27 Methyltransferase type 12 - - - 0.0000000000000000001885 97.0
HFD2_k127_5405688_28 Papain family cysteine protease - - - 0.0000000000000000001969 99.0
HFD2_k127_5405688_29 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000008609 99.0
HFD2_k127_5405688_3 Dihydropyrimidinase K01464 - 3.5.2.2 3.37e-221 694.0
HFD2_k127_5405688_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 7.829e-220 691.0
HFD2_k127_5405688_5 ATP-dependent helicase K03579 - 3.6.4.13 1.147e-205 679.0
HFD2_k127_5405688_6 HpcH/HpaI aldolase/citrate lyase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 571.0
HFD2_k127_5405688_7 Ferredoxin oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 572.0
HFD2_k127_5405688_8 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 540.0
HFD2_k127_5405688_9 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 513.0
HFD2_k127_5406247_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1519.0
HFD2_k127_5406247_1 Glycosyl hydrolase family 1 K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 601.0
HFD2_k127_5406247_10 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000304 81.0
HFD2_k127_5406247_11 Acetyltransferase (GNAT) domain - - - 0.000000000000000389 89.0
HFD2_k127_5406247_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 343.0
HFD2_k127_5406247_3 helix_turn _helix lactose operon repressor K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 339.0
HFD2_k127_5406247_4 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 327.0
HFD2_k127_5406247_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000004558 213.0
HFD2_k127_5406247_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000001168 211.0
HFD2_k127_5406247_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000004072 158.0
HFD2_k127_5406247_8 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000000000000000000000004696 119.0
HFD2_k127_5406247_9 Ribosomal protein L33 K02913 - - 0.0000000000000000000004137 98.0
HFD2_k127_5427558_0 Domain of unknown function (DUF3367) K16648 - - 0.0 1154.0
HFD2_k127_5427558_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1137.0
HFD2_k127_5427558_10 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 518.0
HFD2_k127_5427558_11 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 516.0
HFD2_k127_5427558_12 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005935 489.0
HFD2_k127_5427558_13 Belongs to the ABC transporter superfamily K02031,K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 460.0
HFD2_k127_5427558_14 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006149 460.0
HFD2_k127_5427558_15 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 452.0
HFD2_k127_5427558_16 cytosine deaminase K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008322 392.0
HFD2_k127_5427558_17 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 393.0
HFD2_k127_5427558_18 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 372.0
HFD2_k127_5427558_19 Creatininase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006533 349.0
HFD2_k127_5427558_2 Protein synonym acyl-CoA synthetase K01897 - 6.2.1.3 5.174e-258 815.0
HFD2_k127_5427558_20 Creatininase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 347.0
HFD2_k127_5427558_21 3-methyladenine DNA glycosylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 349.0
HFD2_k127_5427558_22 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 325.0
HFD2_k127_5427558_23 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 322.0
HFD2_k127_5427558_24 Xanthine dehydrogenase iron-sulfur cluster and FAD-binding subunit A K13481 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 324.0
HFD2_k127_5427558_25 Hydrolase CocE NonD family K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 317.0
HFD2_k127_5427558_26 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 292.0
HFD2_k127_5427558_27 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 304.0
HFD2_k127_5427558_28 PFAM Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 291.0
HFD2_k127_5427558_29 phosphoribosyltransferase K07101 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 283.0
HFD2_k127_5427558_3 Protein of unknown function (DUF512) - - - 1.975e-215 676.0
HFD2_k127_5427558_30 FMN binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004567 269.0
HFD2_k127_5427558_31 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000002154 267.0
HFD2_k127_5427558_32 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000461 255.0
HFD2_k127_5427558_33 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000007088 250.0
HFD2_k127_5427558_34 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001446 253.0
HFD2_k127_5427558_35 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000007119 248.0
HFD2_k127_5427558_36 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000004136 224.0
HFD2_k127_5427558_37 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000003385 212.0
HFD2_k127_5427558_38 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000005186 196.0
HFD2_k127_5427558_39 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000827 192.0
HFD2_k127_5427558_4 FAD dependent oxidoreductase - - - 4.943e-214 675.0
HFD2_k127_5427558_40 PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000003972 184.0
HFD2_k127_5427558_41 Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000001588 166.0
HFD2_k127_5427558_42 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000004969 153.0
HFD2_k127_5427558_43 sigma-70 region 2 K03088 - - 0.00000000000000000000000000000006891 137.0
HFD2_k127_5427558_44 Transglutaminase-like superfamily - - - 0.000000000000000000000000000004962 138.0
HFD2_k127_5427558_45 - - - - 0.000000000000000000000000001658 116.0
HFD2_k127_5427558_46 - - - - 0.0000000000000000000000006394 106.0
HFD2_k127_5427558_47 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000004869 109.0
HFD2_k127_5427558_48 PFAM luciferase-like K00320 - 1.5.98.2 0.0000000000000000000000858 111.0
HFD2_k127_5427558_49 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000007926 105.0
HFD2_k127_5427558_5 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 7.796e-212 669.0
HFD2_k127_5427558_6 Acyl-CoA dehydrogenase, N-terminal domain - - - 1.715e-199 627.0
HFD2_k127_5427558_7 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 4.073e-195 625.0
HFD2_k127_5427558_8 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007326 556.0
HFD2_k127_5427558_9 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 544.0
HFD2_k127_5478431_0 Thiamine pyrophosphate enzyme, central domain K03336 - 3.7.1.22 1.435e-234 740.0
HFD2_k127_5478431_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 513.0
HFD2_k127_5478431_10 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000998 210.0
HFD2_k127_5478431_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 451.0
HFD2_k127_5478431_3 Aminotransferase class I and II K14261 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 391.0
HFD2_k127_5478431_4 KduI/IolB family K03337 - 5.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 396.0
HFD2_k127_5478431_5 pfkB family carbohydrate kinase K03338 - 2.7.1.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 370.0
HFD2_k127_5478431_6 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 357.0
HFD2_k127_5478431_7 deoxyribose-phosphate aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 304.0
HFD2_k127_5478431_8 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002483 284.0
HFD2_k127_5478431_9 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001669 259.0
HFD2_k127_5497537_0 Filamentation induced by cAMP protein fic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 484.0
HFD2_k127_5497537_1 Protein of unknown function DUF262 - - - 0.0000000000000000000000002507 110.0
HFD2_k127_5497537_2 PFAM WD40 domain protein beta Propeller - - - 0.00001324 50.0
HFD2_k127_5497537_3 CHAT domain - - - 0.0006809 48.0
HFD2_k127_5580863_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 5e-324 1002.0
HFD2_k127_5580863_1 Seryl-tRNA synthetase N-terminal domain K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 570.0
HFD2_k127_5580863_10 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000003471 233.0
HFD2_k127_5580863_11 - - - - 0.00000000000000000000000000000000000000000000000000000001303 219.0
HFD2_k127_5580863_12 Cytochrome c biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000000000000000000000006268 206.0
HFD2_k127_5580863_13 Thioesterase K07107 - - 0.000000000000000000000000000000000000000000000000002911 186.0
HFD2_k127_5580863_14 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000001475 188.0
HFD2_k127_5580863_15 ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.00000000000000000000000000000000000003007 149.0
HFD2_k127_5580863_16 Redoxin - - - 0.0000000000000000000000000000000000006837 147.0
HFD2_k127_5580863_17 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18958 GO:0001101,GO:0008150,GO:0010033,GO:0033993,GO:0042221,GO:0046677,GO:0050896,GO:0070542,GO:1901700 - 0.0000000000000000000000000000000003001 140.0
HFD2_k127_5580863_19 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.000000000000000000000000003245 114.0
HFD2_k127_5580863_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 492.0
HFD2_k127_5580863_21 - - - - 0.0002017 51.0
HFD2_k127_5580863_3 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02298 - 1.10.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 446.0
HFD2_k127_5580863_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 399.0
HFD2_k127_5580863_5 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) K02862 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009956 353.0
HFD2_k127_5580863_6 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 306.0
HFD2_k127_5580863_7 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002558 271.0
HFD2_k127_5580863_8 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0010181,GO:0016491,GO:0016614,GO:0016899,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032553,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042803,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000009527 269.0
HFD2_k127_5580863_9 Replication protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004512 256.0
HFD2_k127_562805_0 PFAM Glycoside hydrolase, family 38 K01191 - 3.2.1.24 0.0 1026.0
HFD2_k127_562805_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004658 574.0
HFD2_k127_562805_10 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 363.0
HFD2_k127_562805_11 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 393.0
HFD2_k127_562805_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 331.0
HFD2_k127_562805_13 MATE efflux family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 323.0
HFD2_k127_562805_14 N-6 DNA Methylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 310.0
HFD2_k127_562805_15 hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001576 256.0
HFD2_k127_562805_16 dna ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000002017 248.0
HFD2_k127_562805_17 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000009165 215.0
HFD2_k127_562805_18 Cupin superfamily (DUF985) K09705 - - 0.000000000000000000000000000000000000000000000000000000006556 203.0
HFD2_k127_562805_19 HTH domain - - - 0.0000000000000000000000000000000000000000001877 166.0
HFD2_k127_562805_2 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 550.0
HFD2_k127_562805_20 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000472 135.0
HFD2_k127_562805_21 Nudix hydrolase - - - 0.0000000000000000000000000000001482 129.0
HFD2_k127_562805_23 Thiamine-binding protein - - - 0.0000000000006234 72.0
HFD2_k127_562805_24 response regulator - - - 0.0000000004224 61.0
HFD2_k127_562805_25 - - - - 0.0000000004722 73.0
HFD2_k127_562805_26 peptidoglycan-binding domain-containing protein - - - 0.0000000005659 72.0
HFD2_k127_562805_3 Alcohol dehydrogenase groes K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 496.0
HFD2_k127_562805_4 Protein synonym peptidase M K01265 GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 484.0
HFD2_k127_562805_5 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 485.0
HFD2_k127_562805_6 (Pantothenic acid kinase)) K00867 GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 463.0
HFD2_k127_562805_7 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 446.0
HFD2_k127_562805_8 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007283 438.0
HFD2_k127_562805_9 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 405.0
HFD2_k127_5637304_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K03520 - 1.2.5.3 1.69e-257 815.0
HFD2_k127_5637304_1 MacB-like periplasmic core domain K02004 - - 7.265e-229 737.0
HFD2_k127_5637304_10 ABC transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 424.0
HFD2_k127_5637304_11 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 362.0
HFD2_k127_5637304_12 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 342.0
HFD2_k127_5637304_13 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008034 284.0
HFD2_k127_5637304_14 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000126 272.0
HFD2_k127_5637304_15 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001666 242.0
HFD2_k127_5637304_16 GyrI-like small molecule binding domain - - - 0.0000000000000000000000000000000000000000000000002602 189.0
HFD2_k127_5637304_17 transcriptional regulator (MarR - - - 0.0000000000000000000000000000000001761 137.0
HFD2_k127_5637304_18 - - - - 0.000000000000000000004781 98.0
HFD2_k127_5637304_19 Bacterial transcriptional activator domain - - - 0.0000000000000000003271 100.0
HFD2_k127_5637304_2 HD domain - - - 4.587e-210 677.0
HFD2_k127_5637304_20 PFAM regulatory protein, ArsR K03892 - - 0.00000000000002379 76.0
HFD2_k127_5637304_21 Flavodoxin domain K00230 - 1.3.5.3 0.0004564 50.0
HFD2_k127_5637304_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 597.0
HFD2_k127_5637304_4 Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008707 484.0
HFD2_k127_5637304_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 509.0
HFD2_k127_5637304_6 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 472.0
HFD2_k127_5637304_7 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 467.0
HFD2_k127_5637304_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 442.0
HFD2_k127_5637304_9 Voltage gated chloride channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 428.0
HFD2_k127_5655060_0 xylulose kinase K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006414 538.0
HFD2_k127_5655060_1 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 471.0
HFD2_k127_5655060_10 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008883 336.0
HFD2_k127_5655060_12 ABC transporter, ATP-binding protein K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 324.0
HFD2_k127_5655060_13 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 289.0
HFD2_k127_5655060_14 D-amino acid K00285 - 1.4.5.1 0.000000000000000000000000000000000000000000000000000000000000000000007709 250.0
HFD2_k127_5655060_15 ornithine cyclodeaminase K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000001832 191.0
HFD2_k127_5655060_16 Heat shock protein DnaJ domain protein K05516 - - 0.000000000000000000000000000000000001009 151.0
HFD2_k127_5655060_17 Telomere recombination K07566 - 2.7.7.87 0.00000000000000000000002867 102.0
HFD2_k127_5655060_18 EamA-like transporter family - - - 0.000000006812 66.0
HFD2_k127_5655060_19 cytochrome oxidase assembly K02259 - - 0.0006697 45.0
HFD2_k127_5655060_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 445.0
HFD2_k127_5655060_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K02549,K19802,K21624 - 4.2.1.113,4.2.1.171,5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 433.0
HFD2_k127_5655060_4 Arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 419.0
HFD2_k127_5655060_5 Domain of unknown function (DUF1989) K09967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 410.0
HFD2_k127_5655060_6 Proline racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 380.0
HFD2_k127_5655060_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 370.0
HFD2_k127_5655060_8 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 361.0
HFD2_k127_5655060_9 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 344.0
HFD2_k127_5678708_0 metallocarboxypeptidase activity - - - 3.963e-244 766.0
HFD2_k127_5678708_1 Glycosyltransferase, MGT family - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0020012,GO:0030682,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044464,GO:0046467,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 608.0
HFD2_k127_5678708_10 B domain of TMEM189, localisation domain K20656 - - 0.000000000000000000000000000000000108 141.0
HFD2_k127_5678708_2 drug exporters of the RND superfamily K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 476.0
HFD2_k127_5678708_3 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 392.0
HFD2_k127_5678708_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 358.0
HFD2_k127_5678708_5 sugar isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 304.0
HFD2_k127_5678708_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 318.0
HFD2_k127_5678708_7 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001172 278.0
HFD2_k127_5678708_8 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002703 268.0
HFD2_k127_5678708_9 Aminoglycoside phosphotransferase K16146 - 2.7.1.175 0.000000000000000000000000000000000000000000000000001262 198.0
HFD2_k127_5839931_0 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.0 1163.0
HFD2_k127_5839931_1 ABC transporter K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 498.0
HFD2_k127_5839931_2 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 441.0
HFD2_k127_5839931_3 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 452.0
HFD2_k127_5839931_4 DeoR C terminal sensor domain K03436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009794 306.0
HFD2_k127_5846574_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K00187 - 1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 469.0
HFD2_k127_5846574_1 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 371.0
HFD2_k127_5846574_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000001076 201.0
HFD2_k127_5846574_3 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000000000000001041 144.0
HFD2_k127_5846574_4 NAD(P)H-dependent FMN reductase - - - 0.00000000000000000000000008078 112.0
HFD2_k127_5846574_5 Protein of unknown function (DUF3995) - - - 0.00000000000000009155 89.0
HFD2_k127_5846574_6 Cupin domain - - - 0.00000001334 62.0
HFD2_k127_5848530_0 B3/4 domain K01890 - 6.1.1.20 1.531e-304 951.0
HFD2_k127_5848530_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 2.268e-210 659.0
HFD2_k127_5848530_10 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000372 253.0
HFD2_k127_5848530_11 Guanylate kinase homologues. K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000005156 253.0
HFD2_k127_5848530_12 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001217 247.0
HFD2_k127_5848530_13 Methyltransferase small domain K00564 - 2.1.1.172 0.00000000000000000000000000000000000000000000000000000000000000000008216 236.0
HFD2_k127_5848530_14 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000202 213.0
HFD2_k127_5848530_15 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.000000000000000000000000000000000000000000000000000000000002591 219.0
HFD2_k127_5848530_16 SpoU rRNA Methylase family K03437 - - 0.0000000000000000000000000000000000000000000000000000002808 205.0
HFD2_k127_5848530_17 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000004066 177.0
HFD2_k127_5848530_18 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.000000000000000000000000000000000002637 143.0
HFD2_k127_5848530_19 - - - - 0.0000000000000000000000000000002704 126.0
HFD2_k127_5848530_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 545.0
HFD2_k127_5848530_20 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000004045 114.0
HFD2_k127_5848530_21 enzyme binding K00567,K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 2.1.1.63 0.00000000000000000000000001782 113.0
HFD2_k127_5848530_22 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000001406 93.0
HFD2_k127_5848530_24 Belongs to the UPF0301 (AlgH) family K07735 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000003064 61.0
HFD2_k127_5848530_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 563.0
HFD2_k127_5848530_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000867 432.0
HFD2_k127_5848530_5 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 419.0
HFD2_k127_5848530_6 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 413.0
HFD2_k127_5848530_7 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 390.0
HFD2_k127_5848530_8 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007697 325.0
HFD2_k127_5848530_9 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 322.0
HFD2_k127_5848799_0 Belongs to the GcvT family K19191 GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006575,GO:0006576,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008480,GO:0009056,GO:0009063,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019695,GO:0019752,GO:0019842,GO:0031406,GO:0031974,GO:0033218,GO:0034641,GO:0035999,GO:0036094,GO:0042133,GO:0042135,GO:0042219,GO:0042402,GO:0042426,GO:0042558,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0046483,GO:0046653,GO:0046997,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0055114,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0072341,GO:0097159,GO:0097164,GO:1901052,GO:1901053,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.5.3.19 0.0 1320.0
HFD2_k127_5848799_1 FAD dependent oxidoreductase K19191 - 1.5.3.19 0.0 1070.0
HFD2_k127_5848799_2 Saccharopine dehydrogenase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008346 462.0
HFD2_k127_5848799_3 glycine betaine K02000 - 3.6.3.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 410.0
HFD2_k127_5848799_4 ABC-type proline glycine betaine transport system permease component K02001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 411.0
HFD2_k127_5848799_5 Choline/ethanolamine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 357.0
HFD2_k127_5848799_6 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000431 268.0
HFD2_k127_5848799_7 Substrate binding domain of ABC-type glycine betaine transport system K02002 - - 0.000000000000000000000000000000000000000000000000000000000000000001628 240.0
HFD2_k127_5848799_8 Exopolysaccharide synthesis, ExoD - - - 0.00000000000000000000000000000000000001252 151.0
HFD2_k127_5848799_9 glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.0000000000000261 74.0
HFD2_k127_5851022_0 PFAM AMP-dependent synthetase and ligase K00666 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 - 1.877e-218 694.0
HFD2_k127_5851022_1 Xaa-Pro aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 513.0
HFD2_k127_5851022_2 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 469.0
HFD2_k127_5851022_3 COG1404 Subtilisin-like serine proteases K14645 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 404.0
HFD2_k127_5851022_4 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006538 393.0
HFD2_k127_5851022_5 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006524 275.0
HFD2_k127_5851022_6 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.000000000000000000000000002049 119.0
HFD2_k127_5851815_0 Histidine kinase - - - 0.0 2222.0
HFD2_k127_5851815_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 588.0
HFD2_k127_5851815_10 DNA synthesis involved in DNA repair - - - 0.000000000000000000000000000000000000000000000003295 183.0
HFD2_k127_5851815_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000005446 187.0
HFD2_k127_5851815_12 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000000000000000000000000005394 125.0
HFD2_k127_5851815_13 - - - - 0.0000000000000000000000000000004783 129.0
HFD2_k127_5851815_15 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000002202 87.0
HFD2_k127_5851815_16 Belongs to the anti-sigma-factor antagonist family K06378 - - 0.000000001101 64.0
HFD2_k127_5851815_2 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 342.0
HFD2_k127_5851815_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 324.0
HFD2_k127_5851815_4 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 302.0
HFD2_k127_5851815_5 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 324.0
HFD2_k127_5851815_6 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003238 260.0
HFD2_k127_5851815_7 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000000000000006618 214.0
HFD2_k127_5851815_8 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.00000000000000000000000000000000000000000000000000000002802 204.0
HFD2_k127_5851815_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000001243 197.0
HFD2_k127_5906204_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1566.0
HFD2_k127_5906204_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 480.0
HFD2_k127_5906204_2 rRNA (adenine-N6,N6-)-dimethyltransferase activity K02528,K20444 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000003943 130.0
HFD2_k127_5906204_3 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000005324 88.0
HFD2_k127_5926419_0 Belongs to the peptidase S8 family - - - 0.0 1375.0
HFD2_k127_5926419_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 1.747e-260 811.0
HFD2_k127_5926419_10 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 375.0
HFD2_k127_5926419_11 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 358.0
HFD2_k127_5926419_12 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 353.0
HFD2_k127_5926419_13 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 329.0
HFD2_k127_5926419_14 Short-chain dehydrogenase reductase sdr K14633 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006672 322.0
HFD2_k127_5926419_15 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 322.0
HFD2_k127_5926419_16 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 319.0
HFD2_k127_5926419_17 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00854,K00862,K00880 - 2.7.1.17,2.7.1.215,2.7.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 322.0
HFD2_k127_5926419_18 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005782 304.0
HFD2_k127_5926419_19 Glycosyl transferases group 1 K08256 - 2.4.1.345 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 300.0
HFD2_k127_5926419_2 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 4.158e-212 670.0
HFD2_k127_5926419_20 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008261 266.0
HFD2_k127_5926419_21 Rubrerythrin K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000004946 258.0
HFD2_k127_5926419_22 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000008694 243.0
HFD2_k127_5926419_23 transcriptional regulator K16137 - - 0.00000000000000000000000000000000000000000000000000000000000000000261 239.0
HFD2_k127_5926419_24 Glucose-regulated metallo-peptidase M90 K09933 - - 0.00000000000000000000000000000000000000000000000000000000000001416 224.0
HFD2_k127_5926419_25 Domain of unknown function (DUF1932) - - - 0.000000000000000000000000000000000000000000000000000000000001069 224.0
HFD2_k127_5926419_26 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000004117 205.0
HFD2_k127_5926419_27 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000001122 210.0
HFD2_k127_5926419_28 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000005926 206.0
HFD2_k127_5926419_29 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000000000000000008899 174.0
HFD2_k127_5926419_3 efflux transmembrane transporter activity K02004 - - 3.658e-205 664.0
HFD2_k127_5926419_30 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template - - - 0.0000000000000000000000000000000000000001568 152.0
HFD2_k127_5926419_31 protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.000000000000000000000000000000000000005972 165.0
HFD2_k127_5926419_32 Cbs domain - - - 0.00000000000000000000000000000000000001195 148.0
HFD2_k127_5926419_33 Predicted membrane protein (DUF2231) - - - 0.00000000000000000000000000000125 128.0
HFD2_k127_5926419_34 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000001852 115.0
HFD2_k127_5926419_35 Rhodanese Homology Domain - - - 0.000000000000000000000002592 110.0
HFD2_k127_5926419_36 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000001642 106.0
HFD2_k127_5926419_37 helix_turn_helix, cAMP Regulatory protein K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0000000000000000004176 100.0
HFD2_k127_5926419_38 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000008575 88.0
HFD2_k127_5926419_39 2TM domain - - - 0.000000000002134 75.0
HFD2_k127_5926419_4 Pyridoxal-dependent decarboxylase conserved domain K01634,K18933 - 4.1.1.11,4.1.1.25,4.1.2.27 1.322e-194 626.0
HFD2_k127_5926419_40 antisigma factor binding K04749 - - 0.000000002465 63.0
HFD2_k127_5926419_41 AMP binding - - - 0.000001029 57.0
HFD2_k127_5926419_42 antisigma factor binding - - - 0.00006611 54.0
HFD2_k127_5926419_43 Histidine kinase-like ATPase domain - - - 0.0003351 51.0
HFD2_k127_5926419_44 iron ion binding - - - 0.0009866 50.0
HFD2_k127_5926419_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 567.0
HFD2_k127_5926419_6 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 528.0
HFD2_k127_5926419_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 518.0
HFD2_k127_5926419_8 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 409.0
HFD2_k127_5926419_9 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 389.0
HFD2_k127_602591_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 4.549e-280 872.0
HFD2_k127_602591_1 AMP-binding enzyme C-terminal domain - - - 5.477e-242 758.0
HFD2_k127_602591_2 Saccharopine dehydrogenase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009494 589.0
HFD2_k127_602591_3 Divergent 4Fe-4S mono-cluster K05337 - - 0.000000000000000000000008043 106.0
HFD2_k127_602591_4 nuclease K01174 - 3.1.31.1 0.0000000000000000001659 96.0
HFD2_k127_6052468_0 Aldehyde dehydrogenase K04072,K15515 - 1.1.1.1,1.2.1.10,1.2.1.81 0.0 1170.0
HFD2_k127_6052468_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652,K12673 - 2.2.1.6,2.5.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 415.0
HFD2_k127_6052468_10 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.00000000000000000000000000000001539 139.0
HFD2_k127_6052468_11 - - - - 0.0000000000000817 73.0
HFD2_k127_6052468_2 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K19189 - 1.14.13.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 342.0
HFD2_k127_6052468_3 resistance ABC transporter ATPase subunit K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009244 319.0
HFD2_k127_6052468_4 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001009 289.0
HFD2_k127_6052468_5 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005711 256.0
HFD2_k127_6052468_6 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004678 257.0
HFD2_k127_6052468_7 ABC-2 type transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002769 257.0
HFD2_k127_6052468_8 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000000000000000000000000000000000000000000000007645 229.0
HFD2_k127_6052468_9 belongs to the sigma-70 factor family K03088 - - 0.000000000000000000000000000000000000001256 150.0
HFD2_k127_6071177_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 7.052e-294 905.0
HFD2_k127_6071177_1 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007424 560.0
HFD2_k127_6071177_10 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002463 247.0
HFD2_k127_6071177_12 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000000000000000000000000000003962 183.0
HFD2_k127_6071177_13 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000287 177.0
HFD2_k127_6071177_14 - - - - 0.000000000000000000000000000000000000000000369 162.0
HFD2_k127_6071177_15 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000003278 166.0
HFD2_k127_6071177_16 Acetyltransferase (GNAT) domain K06977 - - 0.000000000000000000000000000000000000001524 152.0
HFD2_k127_6071177_17 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000001549 133.0
HFD2_k127_6071177_18 lactoylglutathione lyase activity - - - 0.000000000000000000000000006782 114.0
HFD2_k127_6071177_19 Nucleoside 2-deoxyribosyltransferase like K08728 - 2.4.2.6 0.0000000000000000000007096 100.0
HFD2_k127_6071177_2 Aminotransferase K00812,K14267 - 2.6.1.1,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 513.0
HFD2_k127_6071177_21 Ribbon-helix-helix protein, copG family - - - 0.0000000001046 63.0
HFD2_k127_6071177_22 Cupredoxin-like domain - - - 0.000003613 56.0
HFD2_k127_6071177_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 450.0
HFD2_k127_6071177_4 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 451.0
HFD2_k127_6071177_5 Calcineurin-like phosphoesterase K03651 - 3.1.4.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 424.0
HFD2_k127_6071177_6 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 365.0
HFD2_k127_6071177_7 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009003 340.0
HFD2_k127_6071177_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 320.0
HFD2_k127_6071177_9 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006785 318.0
HFD2_k127_6165357_0 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 552.0
HFD2_k127_6165357_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001277 266.0
HFD2_k127_6165357_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000007332 233.0
HFD2_k127_6165357_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000001343 133.0
HFD2_k127_6165357_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000001731 102.0
HFD2_k127_6165357_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000003709 85.0
HFD2_k127_6165357_6 - - - - 0.0000003162 63.0
HFD2_k127_619903_0 Epoxide hydrolase N terminus K21159 - - 4.33e-197 620.0
HFD2_k127_619903_1 Transketolase, C-terminal domain K00167 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 582.0
HFD2_k127_619903_10 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 312.0
HFD2_k127_619903_11 SMP-30/Gluconolaconase/LRE-like region K01053,K14274 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 310.0
HFD2_k127_619903_12 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 313.0
HFD2_k127_619903_13 SMP-30/Gluconolaconase/LRE-like region K01053,K14274 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 311.0
HFD2_k127_619903_14 electron transport chain K00347,K03614,K21163 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002168 294.0
HFD2_k127_619903_15 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000369 258.0
HFD2_k127_619903_16 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000001598 258.0
HFD2_k127_619903_17 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000008354 246.0
HFD2_k127_619903_18 import. Responsible for energy coupling to the transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000004297 239.0
HFD2_k127_619903_19 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000003804 228.0
HFD2_k127_619903_2 Dehydrogenase E1 component K00166 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 559.0
HFD2_k127_619903_20 NAD(P)H dehydrogenase (quinone) activity K00355 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000001311 214.0
HFD2_k127_619903_21 NAD(P)H dehydrogenase (quinone) activity K00355 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000004235 208.0
HFD2_k127_619903_22 LysE type translocator K11250 - - 0.0000000000000000000000000000000000000000000000000002515 193.0
HFD2_k127_619903_23 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000001632 180.0
HFD2_k127_619903_24 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000004561 170.0
HFD2_k127_619903_25 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000003469 156.0
HFD2_k127_619903_26 transcriptional regulator - - - 0.000000000000000000000000000000000000008407 151.0
HFD2_k127_619903_27 Branched-chain amino acid transport system / permease component K10440 - - 0.000000000000000000000000000002799 134.0
HFD2_k127_619903_29 SnoaL-like domain - - - 0.00000000000000000000008609 110.0
HFD2_k127_619903_3 Alcohol dehydrogenase GroES-like domain K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 481.0
HFD2_k127_619903_30 SnoaL-like domain - - - 0.0000000000000000000005177 108.0
HFD2_k127_619903_31 SnoaL-like domain - - - 0.000000007639 64.0
HFD2_k127_619903_32 - - - - 0.00006916 51.0
HFD2_k127_619903_4 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 473.0
HFD2_k127_619903_5 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K09699 - 2.3.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 442.0
HFD2_k127_619903_6 import. Responsible for energy coupling to the transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000931 432.0
HFD2_k127_619903_7 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 358.0
HFD2_k127_619903_8 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 349.0
HFD2_k127_619903_9 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 327.0
HFD2_k127_6200345_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 1.213e-275 865.0
HFD2_k127_6200345_1 glutamine synthetase K01915 - 6.3.1.2 1.713e-233 729.0
HFD2_k127_6200345_10 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 515.0
HFD2_k127_6200345_11 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007627 472.0
HFD2_k127_6200345_12 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 464.0
HFD2_k127_6200345_13 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 458.0
HFD2_k127_6200345_14 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 426.0
HFD2_k127_6200345_15 Scramblase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 400.0
HFD2_k127_6200345_16 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 397.0
HFD2_k127_6200345_17 Belongs to the Glu Leu Phe Val dehydrogenases family K00270 - 1.4.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 385.0
HFD2_k127_6200345_18 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 369.0
HFD2_k127_6200345_19 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 364.0
HFD2_k127_6200345_2 Amidohydrolase family - - - 2.222e-227 710.0
HFD2_k127_6200345_20 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005718 368.0
HFD2_k127_6200345_21 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 319.0
HFD2_k127_6200345_22 Belongs to the NUDIX hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 292.0
HFD2_k127_6200345_23 Pfam:Zinicin_2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006402 299.0
HFD2_k127_6200345_24 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002548 290.0
HFD2_k127_6200345_25 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001487 284.0
HFD2_k127_6200345_26 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003701 278.0
HFD2_k127_6200345_27 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005414 268.0
HFD2_k127_6200345_28 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001397 265.0
HFD2_k127_6200345_29 Anion-transporting ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000005023 244.0
HFD2_k127_6200345_3 Elongation factor SelB, winged helix K03833 - - 1.195e-220 711.0
HFD2_k127_6200345_30 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K00219,K01069 - 1.3.1.34,3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000597 221.0
HFD2_k127_6200345_31 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000005196 220.0
HFD2_k127_6200345_32 RNA polymerase sigma factor K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000009994 215.0
HFD2_k127_6200345_33 - - - - 0.00000000000000000000000000000000000000000000000000000000002019 213.0
HFD2_k127_6200345_34 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000003381 207.0
HFD2_k127_6200345_35 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000005082 193.0
HFD2_k127_6200345_36 helix_turn _helix lactose operon repressor K02525,K02529 - - 0.0000000000000000000000000000000000000000000000133 185.0
HFD2_k127_6200345_38 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000258 194.0
HFD2_k127_6200345_39 Iron-sulphur cluster biosynthesis K13628 - - 0.0000000000000000000000000000000000000000002692 162.0
HFD2_k127_6200345_4 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 5.939e-202 634.0
HFD2_k127_6200345_40 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000005927 168.0
HFD2_k127_6200345_41 DNA-binding transcription factor activity K04096,K20421 - 2.1.1.303 0.0000000000000000000000000000000000000009978 153.0
HFD2_k127_6200345_42 replication factor c K02341,K02343,K09384 - 2.7.7.7 0.0000000000000000000000000000000000007883 143.0
HFD2_k127_6200345_43 MazG nucleotide pyrophosphohydrolase domain - - - 0.000000000000000000000000000000000001631 148.0
HFD2_k127_6200345_44 oxidation-reduction process K09022 - 3.5.99.10 0.000000000000000000000000000000006258 140.0
HFD2_k127_6200345_45 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000003652 130.0
HFD2_k127_6200345_46 Major facilitator Superfamily - - - 0.000000000000000000000000007008 124.0
HFD2_k127_6200345_47 Putative zinc-finger - - - 0.0000000000000000000002689 98.0
HFD2_k127_6200345_48 - - - - 0.0000000000000000005916 98.0
HFD2_k127_6200345_49 Acyltransferase family - - - 0.000000000265 70.0
HFD2_k127_6200345_5 ACT domain K00928 - 2.7.2.4 7.771e-202 634.0
HFD2_k127_6200345_6 pyrroloquinoline quinone binding - - - 2.616e-200 650.0
HFD2_k127_6200345_7 decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 585.0
HFD2_k127_6200345_8 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 545.0
HFD2_k127_6200345_9 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 536.0
HFD2_k127_6213354_0 Type ii secretion system protein e K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009126 525.0
HFD2_k127_6213354_1 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007797 521.0
HFD2_k127_6213354_10 Type ii secretion system - - - 0.00000000000000000000000000000000000000000000000000000000005372 225.0
HFD2_k127_6213354_11 Type II secretion system (T2SS), protein F K12511 - - 0.0000000000000000000000000000000000000000000000000000000001237 217.0
HFD2_k127_6213354_12 oxidoreductase activity K07114 - - 0.0000000000000000000000000000000000000000000000000000005098 207.0
HFD2_k127_6213354_13 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000000000000000000003873 193.0
HFD2_k127_6213354_14 LysM domain K12204 - - 0.00000000000000000000000000000000000000000009285 175.0
HFD2_k127_6213354_15 SAF - - - 0.0000000000000000000000000000000000000000003128 168.0
HFD2_k127_6213354_16 Inositol monophosphatase family K05602 - 3.1.3.15 0.0000000000000000000000000000000000000009905 169.0
HFD2_k127_6213354_18 - - - - 0.00000000000000000000000585 106.0
HFD2_k127_6213354_19 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000007559 103.0
HFD2_k127_6213354_2 PFAM Peptidoglycan-binding LysM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 522.0
HFD2_k127_6213354_25 TadE-like protein - - - 0.00000001848 64.0
HFD2_k127_6213354_26 - - - - 0.00002022 54.0
HFD2_k127_6213354_3 Glycerate kinase family K00865 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 370.0
HFD2_k127_6213354_4 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 346.0
HFD2_k127_6213354_5 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 338.0
HFD2_k127_6213354_6 Protein of unknown function (DUF3500) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 341.0
HFD2_k127_6213354_7 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006331 282.0
HFD2_k127_6213354_8 Phosphoribulokinase / Uridine kinase family K00855,K00876 - 2.7.1.19,2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000005951 249.0
HFD2_k127_6213354_9 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000002041 231.0
HFD2_k127_6217639_0 C-terminal, D2-small domain, of ClpB protein K03696 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - 0.0 1330.0
HFD2_k127_6217639_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 606.0
HFD2_k127_6217639_10 DisA bacterial checkpoint controller linker region K07067 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 412.0
HFD2_k127_6217639_11 Transposase K07493 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 404.0
HFD2_k127_6217639_12 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 414.0
HFD2_k127_6217639_13 carbohydrate transport K05813 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 384.0
HFD2_k127_6217639_14 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006749 354.0
HFD2_k127_6217639_16 PFAM binding-protein-dependent transport systems inner membrane component K05814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 349.0
HFD2_k127_6217639_17 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 336.0
HFD2_k127_6217639_18 Carbohydrate ABC transporter ATP-binding protein, CUT1 family K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007116 330.0
HFD2_k127_6217639_19 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008123 318.0
HFD2_k127_6217639_2 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008471 592.0
HFD2_k127_6217639_20 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001356 280.0
HFD2_k127_6217639_21 Binding-protein-dependent transport systems inner membrane component K02026,K05815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009142 276.0
HFD2_k127_6217639_22 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001576 260.0
HFD2_k127_6217639_23 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003316 258.0
HFD2_k127_6217639_24 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000008299 244.0
HFD2_k127_6217639_25 - - - - 0.00000000000000000000000000000000000000000000000000000000000005496 217.0
HFD2_k127_6217639_26 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000008662 190.0
HFD2_k127_6217639_27 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000003822 182.0
HFD2_k127_6217639_28 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000007422 164.0
HFD2_k127_6217639_29 - - - - 0.000000000000000000000000000000000000000002097 168.0
HFD2_k127_6217639_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 557.0
HFD2_k127_6217639_30 Antibiotic biosynthesis monooxygenase K06996,K21481 - 1.14.99.57 0.0000000000000000000000000000000000000000446 154.0
HFD2_k127_6217639_32 amine dehydrogenase activity - - - 0.000000000000000000000000000000000003914 154.0
HFD2_k127_6217639_33 dehydratase K18122 - - 0.00000000000000000001094 102.0
HFD2_k127_6217639_35 - - - - 0.00001359 57.0
HFD2_k127_6217639_4 FAD binding domain K21401 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016491,GO:0016627,GO:0030312,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 1.3.99.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 565.0
HFD2_k127_6217639_5 KaiC K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 549.0
HFD2_k127_6217639_6 Cytochrome b/b6/petB K03891 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 479.0
HFD2_k127_6217639_7 protein conserved in bacteria K09927 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 450.0
HFD2_k127_6217639_8 Polyprenyl synthetase K00805 - 2.5.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 428.0
HFD2_k127_6217639_9 permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009057 440.0
HFD2_k127_6251859_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 548.0
HFD2_k127_6251859_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000002693 198.0
HFD2_k127_6251859_2 Flavodoxin domain K00230 - 1.3.5.3 0.0000000000000000000000000000000000000000000000000005591 189.0
HFD2_k127_6294151_0 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001458 314.0
HFD2_k127_6294151_1 Rifampin ADP-ribosyl transferase K19062 - - 0.00000000000000000000000000000000000000000000000000003735 192.0
HFD2_k127_6350174_0 Protein synonym hydantoin utilization protein A K01473 - 3.5.2.14 0.0 1012.0
HFD2_k127_6350174_1 Zn-dependent metallo-hydrolase RNA specificity domain K12574 - - 3.073e-271 842.0
HFD2_k127_6350174_10 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000006817 240.0
HFD2_k127_6350174_11 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000005801 201.0
HFD2_k127_6350174_12 Transcriptional regulator K05799 - - 0.00000000000000000000000000000000000000000000000000000001062 212.0
HFD2_k127_6350174_13 molybdenum ion binding K07140 - - 0.000000000000000000000000000000000000000000008163 174.0
HFD2_k127_6350174_14 Belongs to the CinA family K03742 - 3.5.1.42 0.00000000000000000000000000000007282 128.0
HFD2_k127_6350174_15 acyl-L-homoserine-lactone lactonohydrolase activity K13075 - 3.1.1.81 0.000000000000000000000000002988 121.0
HFD2_k127_6350174_17 Activator of Hsp90 ATPase - - - 0.00004487 45.0
HFD2_k127_6350174_2 Protein synonym hydantoin utilization protein B K01474 - 3.5.2.14 9.81e-271 860.0
HFD2_k127_6350174_3 PFAM AMP-dependent synthetase and ligase K02182 - 6.2.1.48 4.662e-210 681.0
HFD2_k127_6350174_4 Ftsk_gamma K03466 - - 1.701e-208 674.0
HFD2_k127_6350174_5 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K14441 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 612.0
HFD2_k127_6350174_6 Rieske 2Fe-2S K00479 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 557.0
HFD2_k127_6350174_7 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008954 387.0
HFD2_k127_6350174_8 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 383.0
HFD2_k127_6350174_9 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.0000000000000000000000000000000000000000000000000000000000000000000000007742 255.0
HFD2_k127_7023438_0 FAD dependent oxidoreductase central domain K19191 - 1.5.3.19 0.0 1200.0
HFD2_k127_7023438_1 FAD dependent oxidoreductase central domain - - - 2.088e-286 902.0
HFD2_k127_7023438_10 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 344.0
HFD2_k127_7023438_11 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 310.0
HFD2_k127_7023438_12 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 304.0
HFD2_k127_7023438_13 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 304.0
HFD2_k127_7023438_14 PFAM cyclase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006949 277.0
HFD2_k127_7023438_15 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000749 290.0
HFD2_k127_7023438_16 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000446 271.0
HFD2_k127_7023438_17 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000001678 241.0
HFD2_k127_7023438_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001298 237.0
HFD2_k127_7023438_19 Molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000004842 218.0
HFD2_k127_7023438_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 516.0
HFD2_k127_7023438_20 PFAM Activator of Hsp90 ATPase 1 family protein - - - 0.00000000000000000000000000000000000000000000000000000000001837 210.0
HFD2_k127_7023438_21 Acetyltransferase (GNAT) domain K03825 - - 0.00000000000000000000000000000000000000000000000000000002104 203.0
HFD2_k127_7023438_22 Diguanylate cyclase with PAS PAC and GAF sensors - - - 0.000000000000000000000000000000000000000000000000000001167 208.0
HFD2_k127_7023438_23 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000002918 201.0
HFD2_k127_7023438_24 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000004015 188.0
HFD2_k127_7023438_25 N-acetylglucosaminylinositol deacetylase activity - - - 0.00000000000000000000000000000000000000000000000002438 195.0
HFD2_k127_7023438_26 - - - - 0.000000000000000000000000000000000000000000000002867 184.0
HFD2_k127_7023438_27 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000002322 180.0
HFD2_k127_7023438_28 of the double-stranded beta helix - - - 0.0000000000000000000000000000000000000000000000615 178.0
HFD2_k127_7023438_29 MaoC like domain - - - 0.0000000000000000000000000000000000000000000001441 187.0
HFD2_k127_7023438_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006521 485.0
HFD2_k127_7023438_30 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.0000000000000000000000000000000000000000000002212 175.0
HFD2_k127_7023438_31 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000004843 173.0
HFD2_k127_7023438_32 SMART Rhodanese domain protein - - - 0.0000000000000000000000000000000000000000000005634 181.0
HFD2_k127_7023438_33 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000000000000000003405 171.0
HFD2_k127_7023438_34 SMART HNH nuclease - - - 0.00000000000000000000000000000000000000007811 165.0
HFD2_k127_7023438_35 transcriptional regulator - - - 0.00000000000000000000000000000001082 136.0
HFD2_k127_7023438_36 PFAM transcriptional regulator PadR family protein - - - 0.00000000000000000000000000000001854 133.0
HFD2_k127_7023438_37 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000002985 124.0
HFD2_k127_7023438_39 - - - - 0.0000000000000000001614 93.0
HFD2_k127_7023438_4 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005822 492.0
HFD2_k127_7023438_41 Baseplate assembly protein - - - 0.00000000000006336 78.0
HFD2_k127_7023438_42 DUF167 K09131 - - 0.0000000000001659 74.0
HFD2_k127_7023438_43 Baseplate assembly protein - - - 0.000000000003619 73.0
HFD2_k127_7023438_44 amine dehydrogenase activity - - - 0.0000000001969 72.0
HFD2_k127_7023438_45 - - - - 0.00004623 53.0
HFD2_k127_7023438_5 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 484.0
HFD2_k127_7023438_6 Ecdysteroid kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007557 448.0
HFD2_k127_7023438_7 TIGRFAM NRAMP (natural resistance-associated macrophage protein) metal ion transporters - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005886 436.0
HFD2_k127_7023438_8 PQQ enzyme repeat K05889,K12132 - 1.1.2.6,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007723 422.0
HFD2_k127_7023438_9 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 389.0
HFD2_k127_7038560_0 RecF/RecN/SMC N terminal domain K03529 - - 0.0 1318.0
HFD2_k127_7038560_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1049.0
HFD2_k127_7038560_10 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 452.0
HFD2_k127_7038560_11 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 434.0
HFD2_k127_7038560_12 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 444.0
HFD2_k127_7038560_13 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 422.0
HFD2_k127_7038560_14 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 382.0
HFD2_k127_7038560_15 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 370.0
HFD2_k127_7038560_16 PFAM LmbE family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 354.0
HFD2_k127_7038560_17 Zc3h12a-like Ribonuclease NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 343.0
HFD2_k127_7038560_18 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 339.0
HFD2_k127_7038560_19 ABC-type spermidine putrescine transport system, permease component I K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 321.0
HFD2_k127_7038560_2 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 9.47e-321 989.0
HFD2_k127_7038560_20 ABC-type spermidine putrescine transport system, permease component II K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009465 320.0
HFD2_k127_7038560_21 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 323.0
HFD2_k127_7038560_22 Bacterial PH domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 293.0
HFD2_k127_7038560_23 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 292.0
HFD2_k127_7038560_24 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002785 284.0
HFD2_k127_7038560_25 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006065 287.0
HFD2_k127_7038560_26 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000001566 277.0
HFD2_k127_7038560_27 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002292 269.0
HFD2_k127_7038560_28 HAD-superfamily hydrolase subfamily IA, variant 3 K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003678 280.0
HFD2_k127_7038560_29 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004204 261.0
HFD2_k127_7038560_3 Dak1_2 K07030 - - 1.45e-222 702.0
HFD2_k127_7038560_30 Cell envelope-related transcriptional attenuator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001233 256.0
HFD2_k127_7038560_31 Protein conserved in bacteria K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000747 216.0
HFD2_k127_7038560_32 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000003078 201.0
HFD2_k127_7038560_33 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000004222 190.0
HFD2_k127_7038560_34 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000002086 189.0
HFD2_k127_7038560_35 - - - - 0.00000000000000000000000000000000000000000000001337 181.0
HFD2_k127_7038560_36 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000008253 172.0
HFD2_k127_7038560_37 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000007523 148.0
HFD2_k127_7038560_39 - - - - 0.0000000000000000000000000000000000002717 154.0
HFD2_k127_7038560_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 1.035e-220 698.0
HFD2_k127_7038560_40 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000000003065 142.0
HFD2_k127_7038560_41 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000004171 143.0
HFD2_k127_7038560_42 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.0000000000000000000000000000000001501 136.0
HFD2_k127_7038560_43 Ribosomal protein S16 K02959 - - 0.0000000000000000000000000000000008614 137.0
HFD2_k127_7038560_44 nuclease activity K07460 - - 0.000000000000000000000000000000001896 136.0
HFD2_k127_7038560_45 Protein of unknown function (DUF2469) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000007321 128.0
HFD2_k127_7038560_46 - - - - 0.0000000000000000000000000000142 121.0
HFD2_k127_7038560_47 Ribosomal L28 family K02902 - - 0.0000000000000000000000000001639 117.0
HFD2_k127_7038560_48 Cold shock K03704 - - 0.0000000000000000000000001047 107.0
HFD2_k127_7038560_49 Acyl-CoA dehydrogenase, C-terminal domain K22219 - 1.14.14.21 0.0000000000000000000000009953 118.0
HFD2_k127_7038560_5 Hydrolase CocE NonD family K06978 - - 5.688e-213 680.0
HFD2_k127_7038560_50 Belongs to the UPF0109 family K06960 GO:0008150,GO:0040007 - 0.000000000000000000000003278 104.0
HFD2_k127_7038560_51 - - - - 0.000000000000000000000008512 117.0
HFD2_k127_7038560_52 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000000000009594 99.0
HFD2_k127_7038560_53 Protein of unknown function (DUF952) - - - 0.00000000000000000003625 103.0
HFD2_k127_7038560_54 - - - - 0.000000000000003352 84.0
HFD2_k127_7038560_6 CoA-transferase family III K01796 - 5.1.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 585.0
HFD2_k127_7038560_7 Acetylornithine deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 519.0
HFD2_k127_7038560_8 Bacterial extracellular solute-binding protein K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006193 496.0
HFD2_k127_7038560_9 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 467.0
HFD2_k127_7163931_0 Heavy metal translocating P-type atpase K01533,K17686 - 3.6.3.4,3.6.3.54 1.137e-305 968.0
HFD2_k127_7163931_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 467.0
HFD2_k127_7163931_10 PFAM AIG2 family protein - - - 0.00000000000000000000000000008731 129.0
HFD2_k127_7163931_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 284.0
HFD2_k127_7163931_3 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001863 250.0
HFD2_k127_7163931_4 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000002836 202.0
HFD2_k127_7163931_5 dioxygenase activity - - - 0.00000000000000000000000000000000000000000000000000002846 197.0
HFD2_k127_7163931_6 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.00000000000000000000000000000000000000000000000449 181.0
HFD2_k127_7163931_7 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000004001 143.0
HFD2_k127_7163931_8 - - - - 0.000000000000000000000000000000007517 134.0
HFD2_k127_7163931_9 PFAM Uncharacterised BCR, COG1937 K21600 - - 0.00000000000000000000000000000007239 126.0
HFD2_k127_7211599_0 DEAD-like helicases superfamily K03724,K06877 - - 0.0 2119.0
HFD2_k127_7211599_1 FAD dependent oxidoreductase central domain K00315 - 1.5.8.4 0.0 1060.0
HFD2_k127_7211599_10 Aldehyde dehydrogenase family K00128 - 1.2.1.3 8.52e-199 632.0
HFD2_k127_7211599_11 Cell division protein FtsA K03569 - - 4.444e-194 607.0
HFD2_k127_7211599_12 mandelate racemase muconate lactonizing K01856 - 5.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 516.0
HFD2_k127_7211599_13 RNB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 517.0
HFD2_k127_7211599_14 PFAM Glycoside hydrolase 15-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 512.0
HFD2_k127_7211599_15 Cytochrome C assembly protein K02198,K04016 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 515.0
HFD2_k127_7211599_16 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 495.0
HFD2_k127_7211599_17 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 479.0
HFD2_k127_7211599_18 Pfam:Zinicin_2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 452.0
HFD2_k127_7211599_19 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 450.0
HFD2_k127_7211599_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 4.211e-293 914.0
HFD2_k127_7211599_20 ROK family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 451.0
HFD2_k127_7211599_21 Flavin containing amine oxidoreductase K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 413.0
HFD2_k127_7211599_22 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 385.0
HFD2_k127_7211599_23 ATPases associated with a variety of cellular activities K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 362.0
HFD2_k127_7211599_24 iron dependent repressor K03709 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 341.0
HFD2_k127_7211599_25 Transcriptional regulatory protein, C terminal K07776 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 341.0
HFD2_k127_7211599_26 Acyl-CoA thioesterase K10805 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 344.0
HFD2_k127_7211599_27 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 344.0
HFD2_k127_7211599_28 Epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 340.0
HFD2_k127_7211599_29 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007197 336.0
HFD2_k127_7211599_3 AAA domain - - - 5.089e-287 950.0
HFD2_k127_7211599_30 His Kinase A (phosphoacceptor) domain K07768 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 319.0
HFD2_k127_7211599_31 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 327.0
HFD2_k127_7211599_32 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 306.0
HFD2_k127_7211599_33 Sortase family K07284 - 3.4.22.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 306.0
HFD2_k127_7211599_34 PhoU domain K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 300.0
HFD2_k127_7211599_35 PFAM Iron-containing alcohol dehydrogenase K19714 GO:0003674,GO:0003824,GO:0004022,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 298.0
HFD2_k127_7211599_36 Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008866 299.0
HFD2_k127_7211599_37 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002882 295.0
HFD2_k127_7211599_38 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001043 281.0
HFD2_k127_7211599_39 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008964 264.0
HFD2_k127_7211599_4 ABC transporter ATPase permease K06147 - - 2.96e-258 811.0
HFD2_k127_7211599_40 CcmB protein K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005583 279.0
HFD2_k127_7211599_41 Aldose 1-epimerase K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000664 240.0
HFD2_k127_7211599_42 MoaE protein K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000009818 232.0
HFD2_k127_7211599_43 Fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000002267 232.0
HFD2_k127_7211599_44 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000006295 220.0
HFD2_k127_7211599_45 collagen metabolic process K18546 - - 0.000000000000000000000000000000000000000000000000000000000005065 230.0
HFD2_k127_7211599_46 Protein of unknown function (DUF1638) - - - 0.0000000000000000000000000000000000000000000000000001773 192.0
HFD2_k127_7211599_47 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000001333 185.0
HFD2_k127_7211599_48 cell redox homeostasis K02199 - - 0.0000000000000000000000000000000000000000000000266 177.0
HFD2_k127_7211599_49 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000005616 173.0
HFD2_k127_7211599_5 Domain of unknown function (DUF4445) - - - 8.342e-235 744.0
HFD2_k127_7211599_50 Sortase family K07284 - 3.4.22.70 0.00000000000000000000000000000000000000000002603 175.0
HFD2_k127_7211599_52 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000002148 154.0
HFD2_k127_7211599_53 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.0000000000000000000000000000000000007241 154.0
HFD2_k127_7211599_54 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.000000000000000000000000000000000002957 140.0
HFD2_k127_7211599_55 - - - - 0.000000000000000000000000000000000004239 140.0
HFD2_k127_7211599_56 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.000000000000000000000000000000000007997 139.0
HFD2_k127_7211599_57 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.0000000000000000000000000000000001344 142.0
HFD2_k127_7211599_59 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000006701 123.0
HFD2_k127_7211599_6 ABC-type multidrug transport system ATPase and permease K06147,K06148 - - 2.745e-228 721.0
HFD2_k127_7211599_61 transcriptional regulator - - - 0.00000000000000000001558 98.0
HFD2_k127_7211599_62 metallopeptidase activity - - - 0.0000000000003037 83.0
HFD2_k127_7211599_63 Virulence factor - - - 0.00000000000209 77.0
HFD2_k127_7211599_64 Domain of unknown function (DUF4190) - - - 0.00000000009225 67.0
HFD2_k127_7211599_66 protein secretion K03116 - - 0.00000001646 58.0
HFD2_k127_7211599_67 Peptidase s1 and s6 chymotrypsin hap K08372 - - 0.00000008304 64.0
HFD2_k127_7211599_68 - - - - 0.0000006594 61.0
HFD2_k127_7211599_7 Trimethylamine methyltransferase (MTTB) - - - 2.989e-217 704.0
HFD2_k127_7211599_8 Glycosyl transferase 4-like domain - - - 3.558e-210 659.0
HFD2_k127_7211599_9 Trimethylamine methyltransferase (MTTB) - - - 3.776e-203 644.0
HFD2_k127_7240251_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 5.766e-196 624.0
HFD2_k127_7240251_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007583 602.0
HFD2_k127_7240251_10 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002935 282.0
HFD2_k127_7240251_11 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004295 280.0
HFD2_k127_7240251_12 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001449 278.0
HFD2_k127_7240251_13 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002091 271.0
HFD2_k127_7240251_14 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000014 267.0
HFD2_k127_7240251_15 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001297 254.0
HFD2_k127_7240251_16 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000005748 244.0
HFD2_k127_7240251_17 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000009286 234.0
HFD2_k127_7240251_18 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000000000000000000000003305 230.0
HFD2_k127_7240251_19 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000000000000106 238.0
HFD2_k127_7240251_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 470.0
HFD2_k127_7240251_20 binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000000006073 200.0
HFD2_k127_7240251_21 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000000000002307 176.0
HFD2_k127_7240251_22 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000112 167.0
HFD2_k127_7240251_23 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000001983 155.0
HFD2_k127_7240251_24 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000001641 145.0
HFD2_k127_7240251_25 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000000000000004496 141.0
HFD2_k127_7240251_26 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.00000000000000000000000000000000306 130.0
HFD2_k127_7240251_27 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000001604 125.0
HFD2_k127_7240251_28 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000001069 115.0
HFD2_k127_7240251_29 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000002296 90.0
HFD2_k127_7240251_3 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 461.0
HFD2_k127_7240251_30 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000004675 75.0
HFD2_k127_7240251_31 Ribosomal protein L30p/L7e K02907 - - 0.00000000000002274 81.0
HFD2_k127_7240251_4 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 400.0
HFD2_k127_7240251_5 ABC transporter K06147,K06148 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 399.0
HFD2_k127_7240251_6 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 390.0
HFD2_k127_7240251_7 CYTH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 367.0
HFD2_k127_7240251_8 ABC transporter transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 366.0
HFD2_k127_7240251_9 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 319.0
HFD2_k127_7243645_0 TOBE domain K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 434.0
HFD2_k127_7243645_1 PFAM extracellular solute-binding protein family 1 K02055,K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007872 369.0
HFD2_k127_7243645_2 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 309.0
HFD2_k127_7243645_3 Binding-protein-dependent transport system inner membrane component K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000012 279.0
HFD2_k127_7243645_4 COG1177 ABC-type spermidine putrescine transport system, permease component II K11070,K11074 - - 0.000000000000000000000000000000000000000000000000000000001541 216.0
HFD2_k127_7243645_5 AsnC family K03718 - - 0.0000000000000000000000000000000000000005624 156.0
HFD2_k127_7243645_6 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.00004194 54.0
HFD2_k127_7267654_0 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007368 406.0
HFD2_k127_7267654_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000002195 139.0
HFD2_k127_7267654_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000575 89.0
HFD2_k127_7267654_3 - - - - 0.000000000000002056 84.0
HFD2_k127_7267654_4 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000004095 85.0
HFD2_k127_7301545_0 Acetyl-CoA carboxylase, central region - - - 9.451e-289 941.0
HFD2_k127_7301545_1 Ketoacyl-synthetase C-terminal extension - - - 1.216e-274 872.0
HFD2_k127_7332732_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 574.0
HFD2_k127_7332732_1 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 445.0
HFD2_k127_7332732_3 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.0000000000000000002499 91.0
HFD2_k127_7332732_4 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - 0.00000003844 55.0
HFD2_k127_7419430_0 DNA Topoisomerase IV K02469 - 5.99.1.3 0.0 1241.0
HFD2_k127_7419430_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 3.276e-258 811.0
HFD2_k127_7419430_10 Uncharacterised protein, DegV family COG1307 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 362.0
HFD2_k127_7419430_11 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 334.0
HFD2_k127_7419430_12 60Kd inner membrane protein K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 321.0
HFD2_k127_7419430_13 May catalyze the transamination reaction in phenylalanine biosynthesis K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 315.0
HFD2_k127_7419430_14 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 301.0
HFD2_k127_7419430_15 Belongs to the ParB family K03497 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001951 278.0
HFD2_k127_7419430_16 Putative peptidoglycan binding domain K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000003834 260.0
HFD2_k127_7419430_17 Putative single-stranded nucleic acids-binding domain K06346 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000956 254.0
HFD2_k127_7419430_18 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002006 247.0
HFD2_k127_7419430_19 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004994 251.0
HFD2_k127_7419430_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 590.0
HFD2_k127_7419430_20 Serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000008269 231.0
HFD2_k127_7419430_21 Single-strand binding protein family K03111 - - 0.00000000000000000000000000000000000000000000000000000000001022 210.0
HFD2_k127_7419430_22 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000003334 211.0
HFD2_k127_7419430_24 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000007344 170.0
HFD2_k127_7419430_25 methyltransferase - - - 0.00000000000000000000000000000000000000000001209 169.0
HFD2_k127_7419430_26 Family of unknown function (DUF5318) - - - 0.00000000000000000000000000000000000000000001393 165.0
HFD2_k127_7419430_27 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000007914 165.0
HFD2_k127_7419430_28 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000001029 164.0
HFD2_k127_7419430_29 - - - - 0.0000000000000000000000000000000000000003748 171.0
HFD2_k127_7419430_3 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 572.0
HFD2_k127_7419430_30 belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000002261 143.0
HFD2_k127_7419430_31 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000003841 134.0
HFD2_k127_7419430_32 Cache domain - - - 0.0000000000000000000000000002391 122.0
HFD2_k127_7419430_33 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000002813 117.0
HFD2_k127_7419430_34 Ribosomal RNA small subunit methyltransferase G K03501 - 2.1.1.170 0.000000000000000000000136 104.0
HFD2_k127_7419430_35 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.00000000000000000000133 100.0
HFD2_k127_7419430_38 FR47-like protein - - - 0.000000000000000005385 98.0
HFD2_k127_7419430_4 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007081 517.0
HFD2_k127_7419430_40 Ribosomal protein L34 K02914 - - 0.0000000000003049 72.0
HFD2_k127_7419430_41 PspC domain - - - 0.000000001251 71.0
HFD2_k127_7419430_42 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0008150,GO:0040007 3.1.26.5 0.0000000107 62.0
HFD2_k127_7419430_5 DNA polymerase III beta subunit K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 494.0
HFD2_k127_7419430_6 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 487.0
HFD2_k127_7419430_7 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007028 476.0
HFD2_k127_7419430_8 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 440.0
HFD2_k127_7419430_9 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 457.0
HFD2_k127_742303_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 2.928e-313 969.0
HFD2_k127_742303_1 Phosphoglycerate kinase K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 561.0
HFD2_k127_742303_2 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 514.0
HFD2_k127_742303_3 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 410.0
HFD2_k127_742303_4 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 379.0
HFD2_k127_742303_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000809 357.0
HFD2_k127_742303_6 transcriptional regulator - - - 0.000000000000000000000000000000000000000005296 175.0
HFD2_k127_7494067_0 Belongs to the RtcB family K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 3.365e-207 653.0
HFD2_k127_7494067_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 629.0
HFD2_k127_7494067_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 364.0
HFD2_k127_7494067_11 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 303.0
HFD2_k127_7494067_12 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007902 327.0
HFD2_k127_7494067_13 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 313.0
HFD2_k127_7494067_14 Short-chain dehydrogenase reductase (SDR) - - - 0.000000000000000000000000000000000000000000000000000000000000000005582 234.0
HFD2_k127_7494067_15 Fungal family of unknown function (DUF1776) - - - 0.0000000000000000000000000000000000000000000000000000005078 214.0
HFD2_k127_7494067_16 Belongs to the peptidase S1B family K01173 - - 0.0000000000000000000000000000000000000000000000003408 193.0
HFD2_k127_7494067_17 Belongs to the globin family - - - 0.0000000000000000000000000000000002159 143.0
HFD2_k127_7494067_18 Transcriptional regulator - - - 0.0000000000000000000000000000000002434 154.0
HFD2_k127_7494067_19 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000004628 127.0
HFD2_k127_7494067_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 559.0
HFD2_k127_7494067_20 Thioesterase-like superfamily - - - 0.000000000000000000000000000002091 132.0
HFD2_k127_7494067_21 Belongs to the globin family - - - 0.0000000000000000000000958 111.0
HFD2_k127_7494067_22 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000001204 91.0
HFD2_k127_7494067_24 Trypsin-like peptidase domain K01173 - - 0.0000000000001595 85.0
HFD2_k127_7494067_25 Predicted membrane protein (DUF2157) - - - 0.000000000005917 80.0
HFD2_k127_7494067_3 Peptidase M1, membrane alanine aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 482.0
HFD2_k127_7494067_4 Capsule synthesis protein K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 473.0
HFD2_k127_7494067_5 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006533 454.0
HFD2_k127_7494067_6 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 431.0
HFD2_k127_7494067_7 alkaline phosphatase K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 410.0
HFD2_k127_7494067_8 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 387.0
HFD2_k127_7494067_9 alkaline phosphatase K01077,K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 381.0
HFD2_k127_7641490_0 Glycosyl transferases group 1 K13668 - 2.4.1.346 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 533.0
HFD2_k127_7641490_1 ROK family K00845,K00886 - 2.7.1.2,2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 399.0
HFD2_k127_7641490_2 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 393.0
HFD2_k127_7641490_3 helix_turn _helix lactose operon repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 329.0
HFD2_k127_7641490_4 ABC transporter substrate-binding protein K02058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 299.0
HFD2_k127_7641490_5 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001206 269.0
HFD2_k127_7641490_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000001535 220.0
HFD2_k127_7641490_7 - - - - 0.0000000000000000000001385 103.0
HFD2_k127_7643131_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 6.59e-300 932.0
HFD2_k127_7643131_1 Glycosyltransferase like family 2 - - - 1.019e-286 915.0
HFD2_k127_7643131_10 glycosyl transferase group 1 K00786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 505.0
HFD2_k127_7643131_11 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 475.0
HFD2_k127_7643131_12 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901576 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 430.0
HFD2_k127_7643131_13 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 413.0
HFD2_k127_7643131_14 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 409.0
HFD2_k127_7643131_15 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007834 406.0
HFD2_k127_7643131_16 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA K00674 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 396.0
HFD2_k127_7643131_17 leucyl aminopeptidase, aminopeptidase T K18028 - 1.13.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 393.0
HFD2_k127_7643131_18 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 387.0
HFD2_k127_7643131_19 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 376.0
HFD2_k127_7643131_2 Psort location CytoplasmicMembrane, score - - - 8.322e-276 879.0
HFD2_k127_7643131_20 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 345.0
HFD2_k127_7643131_21 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 328.0
HFD2_k127_7643131_22 Fumarylacetoacetate (FAA) hydrolase family K18364 - 4.2.1.132,4.2.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 321.0
HFD2_k127_7643131_24 Cell envelope-related transcriptional attenuator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 314.0
HFD2_k127_7643131_25 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 306.0
HFD2_k127_7643131_26 D-alanyl-D-alanine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 304.0
HFD2_k127_7643131_27 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 300.0
HFD2_k127_7643131_28 Fumarylacetoacetate (FAA) hydrolase family K01617 - 4.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002118 284.0
HFD2_k127_7643131_29 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006044 294.0
HFD2_k127_7643131_3 Biotin carboxylase C-terminal domain K11263 - 6.3.4.14,6.4.1.2,6.4.1.3 9.682e-272 862.0
HFD2_k127_7643131_30 dTDP-4-dehydrorhamnose 3,5-epimerase activity K00067,K01710,K01790 - 1.1.1.133,4.2.1.46,5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001801 277.0
HFD2_k127_7643131_31 serine-type endopeptidase activity K04771 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001479 277.0
HFD2_k127_7643131_32 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000731 277.0
HFD2_k127_7643131_33 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003939 246.0
HFD2_k127_7643131_34 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000008628 226.0
HFD2_k127_7643131_35 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000007527 216.0
HFD2_k127_7643131_36 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000002169 185.0
HFD2_k127_7643131_37 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000005843 200.0
HFD2_k127_7643131_38 Alpha beta hydrolase K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000001119 181.0
HFD2_k127_7643131_39 - - - - 0.0000000000000000000000000000000000000000000008688 176.0
HFD2_k127_7643131_4 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 5.179e-264 820.0
HFD2_k127_7643131_40 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000000002916 168.0
HFD2_k127_7643131_41 - - - - 0.0000000000000000000000000000000000000007678 156.0
HFD2_k127_7643131_42 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000004269 151.0
HFD2_k127_7643131_43 amino acid - - - 0.00000000000000000000000000000000000006157 160.0
HFD2_k127_7643131_44 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000008925 139.0
HFD2_k127_7643131_45 SnoaL-like domain K06893 - - 0.000000000000000000000000000000000747 134.0
HFD2_k127_7643131_46 regulation of RNA biosynthetic process - - - 0.0000000000000000000000000000001662 133.0
HFD2_k127_7643131_47 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000005352 129.0
HFD2_k127_7643131_48 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.000000000000000000000000000002434 131.0
HFD2_k127_7643131_49 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.0000000000000000000000005885 107.0
HFD2_k127_7643131_5 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.084e-243 761.0
HFD2_k127_7643131_51 RDD family - - - 0.000000000001434 78.0
HFD2_k127_7643131_52 Iron-containing redox enzyme K06137 - 1.3.3.11 0.00000000001157 74.0
HFD2_k127_7643131_53 Iron-containing redox enzyme K06137 - 1.3.3.11 0.0000000003067 70.0
HFD2_k127_7643131_54 endonuclease activity - - - 0.000000002091 60.0
HFD2_k127_7643131_55 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.00000009213 59.0
HFD2_k127_7643131_56 competence protein K03654 - 3.6.4.12 0.00002072 49.0
HFD2_k127_7643131_57 aldehyde oxidase and xanthine dehydrogenase a b hammerhead - - - 0.0007624 51.0
HFD2_k127_7643131_6 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 9.485e-219 685.0
HFD2_k127_7643131_7 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840 - 5.4.2.8 7.478e-209 657.0
HFD2_k127_7643131_8 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 559.0
HFD2_k127_7643131_9 polysaccharide biosynthetic process K01992 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0008150,GO:0009987,GO:0044764,GO:0046812,GO:0051704 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 535.0
HFD2_k127_7916238_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1150.0
HFD2_k127_7916238_1 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 3.839e-311 968.0
HFD2_k127_7916238_10 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 567.0
HFD2_k127_7916238_11 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 556.0
HFD2_k127_7916238_12 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 550.0
HFD2_k127_7916238_13 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006626 553.0
HFD2_k127_7916238_14 Glycosyl transferase 4-like domain K15521 - 2.4.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 526.0
HFD2_k127_7916238_15 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 507.0
HFD2_k127_7916238_16 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 524.0
HFD2_k127_7916238_17 DNA ligase - GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 477.0
HFD2_k127_7916238_18 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 494.0
HFD2_k127_7916238_19 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 473.0
HFD2_k127_7916238_2 ABC transporter transmembrane region K06147 - - 1.174e-266 837.0
HFD2_k127_7916238_20 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 434.0
HFD2_k127_7916238_21 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 434.0
HFD2_k127_7916238_22 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 435.0
HFD2_k127_7916238_23 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 460.0
HFD2_k127_7916238_24 Delta-aminolevulinic acid dehydratase K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007718 424.0
HFD2_k127_7916238_25 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 413.0
HFD2_k127_7916238_26 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 411.0
HFD2_k127_7916238_27 response to copper ion K07156,K07245,K14166 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 412.0
HFD2_k127_7916238_28 5'-3' exonuclease, C-terminal SAM fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009833 394.0
HFD2_k127_7916238_29 transferase activity, transferring alkyl or aryl (other than methyl) groups K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006872 370.0
HFD2_k127_7916238_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 5.403e-257 815.0
HFD2_k127_7916238_30 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 364.0
HFD2_k127_7916238_31 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 359.0
HFD2_k127_7916238_32 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 348.0
HFD2_k127_7916238_33 transcriptional regulator K01420,K10914,K21561,K21564 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 330.0
HFD2_k127_7916238_34 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 325.0
HFD2_k127_7916238_35 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007306 329.0
HFD2_k127_7916238_36 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 316.0
HFD2_k127_7916238_37 RNA 2'-O ribose methyltransferase substrate binding K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 319.0
HFD2_k127_7916238_38 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 308.0
HFD2_k127_7916238_39 oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 305.0
HFD2_k127_7916238_4 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 1.367e-255 800.0
HFD2_k127_7916238_40 Protein of unknown function (DUF429) K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 295.0
HFD2_k127_7916238_41 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001893 271.0
HFD2_k127_7916238_42 Type IV leader peptidase family K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000002031 264.0
HFD2_k127_7916238_43 Tyrosine phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001629 256.0
HFD2_k127_7916238_44 Glyoxalase-like domain K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000002522 233.0
HFD2_k127_7916238_45 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000003521 239.0
HFD2_k127_7916238_46 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000000003616 246.0
HFD2_k127_7916238_47 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000001999 239.0
HFD2_k127_7916238_48 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000007462 246.0
HFD2_k127_7916238_49 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000269 224.0
HFD2_k127_7916238_5 DNA segregation ATPase FtsK SpoIIIE and related K03466 - - 1.897e-221 735.0
HFD2_k127_7916238_50 Dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000001647 227.0
HFD2_k127_7916238_51 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000004861 212.0
HFD2_k127_7916238_52 PFAM Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000008338 202.0
HFD2_k127_7916238_53 Phage-related minor tail protein K15771,K18642,K20444 - - 0.000000000000000000000000000000000000000000000000000001351 209.0
HFD2_k127_7916238_54 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000005481 192.0
HFD2_k127_7916238_55 of HD superfamily K07023 - - 0.000000000000000000000000000000000000000000000000003981 193.0
HFD2_k127_7916238_56 Glycosyl hydrolases family 18 - - - 0.000000000000000000000000000000000000000000000000209 192.0
HFD2_k127_7916238_57 Protein of unknown function (DUF1203) - - - 0.000000000000000000000000000000000000000000000364 175.0
HFD2_k127_7916238_58 Putative bacterial sensory transduction regulator - - - 0.00000000000000000000000000000000000000000001485 175.0
HFD2_k127_7916238_59 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000000334 164.0
HFD2_k127_7916238_6 Zinc-binding dehydrogenase K17829 - 1.3.1.86 1.312e-214 673.0
HFD2_k127_7916238_60 dna ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000003119 158.0
HFD2_k127_7916238_61 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000001013 165.0
HFD2_k127_7916238_62 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000001104 147.0
HFD2_k127_7916238_63 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.000000000000000000000000000000000002428 147.0
HFD2_k127_7916238_64 GGDEF domain - - - 0.00000000000000000000000000000000001841 150.0
HFD2_k127_7916238_65 - - - - 0.00000000000000000000000000000000004771 143.0
HFD2_k127_7916238_67 Transcriptional regulator K10947 - - 0.000000000000000000000000000000007261 131.0
HFD2_k127_7916238_68 Domain of unknown function (DUF4440) - - - 0.00000000000000000000000000000004954 134.0
HFD2_k127_7916238_69 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000000000000388 125.0
HFD2_k127_7916238_7 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 599.0
HFD2_k127_7916238_70 Helix-turn-helix - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000005294 130.0
HFD2_k127_7916238_73 diguanylate cyclase - - - 0.000000000000000000001923 108.0
HFD2_k127_7916238_74 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000002852 96.0
HFD2_k127_7916238_75 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.000000000000000001677 87.0
HFD2_k127_7916238_76 Glycine betaine ABC transporter substrate-binding protein K05845 - - 0.00000000000000002428 93.0
HFD2_k127_7916238_77 Mo-molybdopterin cofactor metabolic process K03636,K21142 - 2.8.1.12 0.0000000000000001031 85.0
HFD2_k127_7916238_78 Uroporphyrinogen-III synthase HemD K01719,K13542 - 2.1.1.107,4.2.1.75 0.0000000000000002494 93.0
HFD2_k127_7916238_79 PFAM Heavy metal transport detoxification protein - - - 0.00000000000002093 77.0
HFD2_k127_7916238_8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 603.0
HFD2_k127_7916238_80 - - - - 0.000000000000347 79.0
HFD2_k127_7916238_81 Hemerythrin HHE cation binding domain - - - 0.00000000001041 71.0
HFD2_k127_7916238_82 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000001318 70.0
HFD2_k127_7916238_83 - - - - 0.00000000001986 69.0
HFD2_k127_7916238_84 NlpC/P60 family K19223,K19224,K21471 - - 0.000008903 58.0
HFD2_k127_7916238_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 589.0
HFD2_k127_7932270_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 4.335e-234 751.0
HFD2_k127_7932270_1 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 4.866e-221 697.0
HFD2_k127_7932270_10 chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 294.0
HFD2_k127_7932270_11 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 295.0
HFD2_k127_7932270_12 Cytidylate kinase K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000002648 266.0
HFD2_k127_7932270_13 Phosphoglycerate mutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001354 250.0
HFD2_k127_7932270_14 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000005263 250.0
HFD2_k127_7932270_15 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000001562 230.0
HFD2_k127_7932270_16 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000003569 214.0
HFD2_k127_7932270_17 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000009311 188.0
HFD2_k127_7932270_18 Protein of unknown function (DUF3151) - - - 0.000000000000000000000000000000000000000000001147 169.0
HFD2_k127_7932270_19 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000000001959 154.0
HFD2_k127_7932270_2 GTP-binding protein TypA K06207 - - 1.763e-206 659.0
HFD2_k127_7932270_20 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000002283 138.0
HFD2_k127_7932270_21 carboxylic ester hydrolase activity - - - 0.00000000000000000001348 94.0
HFD2_k127_7932270_23 molybdenum cofactor guanylyltransferase activity K03637,K03752,K13818 - 2.7.7.77,4.6.1.17 0.0000000000000005408 88.0
HFD2_k127_7932270_24 COG0607 Rhodanese-related sulfurtransferase - - - 0.0000000000001232 74.0
HFD2_k127_7932270_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 606.0
HFD2_k127_7932270_4 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008571 531.0
HFD2_k127_7932270_5 M18 family aminopeptidase K01267 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 492.0
HFD2_k127_7932270_6 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000847 469.0
HFD2_k127_7932270_7 3-dehydroquinate synthase K16020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 431.0
HFD2_k127_7932270_8 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 412.0
HFD2_k127_7932270_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 324.0
HFD2_k127_7951060_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 313.0
HFD2_k127_7951060_1 Carbon-nitrogen hydrolase K01501 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000001152 242.0
HFD2_k127_7951060_2 Pfam:DUF385 - - - 0.00000000000000000000000000000000001786 141.0
HFD2_k127_7951060_3 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000001482 109.0
HFD2_k127_7951060_4 DNA-binding transcription factor activity - - - 0.0000000000000000000471 95.0
HFD2_k127_7964264_0 KaiC K08482 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 490.0
HFD2_k127_7964264_1 flavoprotein involved in K transport - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 467.0
HFD2_k127_7964264_10 STAS domain - - - 0.00008006 51.0
HFD2_k127_7964264_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 449.0
HFD2_k127_7964264_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 327.0
HFD2_k127_7964264_4 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002071 256.0
HFD2_k127_7964264_5 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000005481 216.0
HFD2_k127_7964264_6 Pfam Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000001547 203.0
HFD2_k127_7964264_7 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000002193 193.0
HFD2_k127_7964264_8 phosphorelay signal transduction system - - - 0.000000000000000000003587 104.0
HFD2_k127_7964264_9 helix_turn_helix, mercury resistance K22491 - - 0.0000000001707 71.0
HFD2_k127_7971070_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 526.0
HFD2_k127_7971070_1 Peptidase family S41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 515.0
HFD2_k127_7971070_10 Serine aminopeptidase, S33 K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000002296 193.0
HFD2_k127_7971070_11 - - - - 0.000000000000000000000000000000000000000000000004036 181.0
HFD2_k127_7971070_12 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000008606 115.0
HFD2_k127_7971070_13 Hemerythrin HHE cation binding domain - - - 0.00000000000000000005605 99.0
HFD2_k127_7971070_14 pyridoxamine 5-phosphate - - - 0.0002382 50.0
HFD2_k127_7971070_2 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 464.0
HFD2_k127_7971070_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007006 435.0
HFD2_k127_7971070_4 Ornithine cyclodeaminase/mu-crystallin family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 397.0
HFD2_k127_7971070_5 Pfam:Pyridox_oxidase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 337.0
HFD2_k127_7971070_6 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 287.0
HFD2_k127_7971070_7 sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000172 242.0
HFD2_k127_7971070_8 transcriptional regulator K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000000001249 240.0
HFD2_k127_7971070_9 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000002079 236.0
HFD2_k127_8112467_0 Pyridoxal-phosphate dependent enzyme K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 534.0
HFD2_k127_8112467_1 protoporphyrinogen oxidase activity K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 494.0
HFD2_k127_8112467_11 PFAM transferase hexapeptide repeat containing protein K00661 - 2.3.1.79 0.0000000000000000000000000000000000005639 146.0
HFD2_k127_8112467_12 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000001739 143.0
HFD2_k127_8112467_13 Aldo/keto reductase family K19265 - - 0.00000000000000000000000000000002479 139.0
HFD2_k127_8112467_14 - - - - 0.0000000000000000000000000000323 127.0
HFD2_k127_8112467_15 Fibronectin type 3 domain K01218 - 3.2.1.78 0.0000000000000000000008265 113.0
HFD2_k127_8112467_16 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000633 84.0
HFD2_k127_8112467_17 dioxygenase activity - - - 0.0000000000003129 79.0
HFD2_k127_8112467_18 spore germination - - - 0.000000004841 61.0
HFD2_k127_8112467_2 Protein of unknown function (DUF1349) K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 453.0
HFD2_k127_8112467_3 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 384.0
HFD2_k127_8112467_4 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 301.0
HFD2_k127_8112467_5 Sortase family K07284 - 3.4.22.70 0.0000000000000000000000000000000000000000000000000000000000000000002449 250.0
HFD2_k127_8112467_6 Fibronectin type 3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001947 258.0
HFD2_k127_8112467_7 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000719 216.0
HFD2_k127_8112467_8 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000005081 161.0
HFD2_k127_8112467_9 GMC oxidoreductase - - - 0.000000000000000000000000000000000000007145 164.0
HFD2_k127_8178652_0 Fe-S oxidoreductase - - - 6.38e-283 887.0
HFD2_k127_8178652_1 Elongator protein 3, MiaB family, Radical SAM K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 528.0
HFD2_k127_8178652_10 Transcriptional regulator, arsR family - - - 0.0000000000000000000000000000001146 126.0
HFD2_k127_8178652_11 - - - - 0.0000000000000000000000001193 111.0
HFD2_k127_8178652_12 sulfur carrier activity - - - 0.0000000000000000000000007167 105.0
HFD2_k127_8178652_13 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.00000000000000000001786 91.0
HFD2_k127_8178652_14 YibE F family protein - - - 0.0000000000657 67.0
HFD2_k127_8178652_2 Electron transfer flavoprotein alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 366.0
HFD2_k127_8178652_3 Lipoate-protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 357.0
HFD2_k127_8178652_4 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001895 284.0
HFD2_k127_8178652_5 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004019 258.0
HFD2_k127_8178652_6 DsrE/DsrF-like family K07092 - - 0.00000000000000000000000000000000000000000000000000000000000000001509 228.0
HFD2_k127_8178652_7 Glycine cleavage H-protein K02437 - - 0.000000000000000000000000000000000000000000000000000000000000000386 223.0
HFD2_k127_8178652_8 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein - - - 0.000000000000000000000000000000000000000000000000000005011 194.0
HFD2_k127_8178652_9 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000004194 190.0
HFD2_k127_8193666_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 9.466e-313 967.0
HFD2_k127_8193666_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 5.324e-295 917.0
HFD2_k127_8193666_10 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 610.0
HFD2_k127_8193666_11 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 606.0
HFD2_k127_8193666_12 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 584.0
HFD2_k127_8193666_13 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 569.0
HFD2_k127_8193666_14 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K12429,K18662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 566.0
HFD2_k127_8193666_15 Cys/Met metabolism PLP-dependent enzyme K01739,K01740,K01761 - 2.5.1.48,2.5.1.49,4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 529.0
HFD2_k127_8193666_16 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 518.0
HFD2_k127_8193666_17 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 522.0
HFD2_k127_8193666_18 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 480.0
HFD2_k127_8193666_19 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 473.0
HFD2_k127_8193666_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.493e-225 722.0
HFD2_k127_8193666_20 ABC-type Fe3 transport system permease component K02011,K02063 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 486.0
HFD2_k127_8193666_21 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 471.0
HFD2_k127_8193666_22 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 466.0
HFD2_k127_8193666_23 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007015 447.0
HFD2_k127_8193666_24 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 415.0
HFD2_k127_8193666_25 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009991 418.0
HFD2_k127_8193666_26 Phytanoyl-CoA dioxygenase (PhyH) K00477,K18565 - 1.14.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 400.0
HFD2_k127_8193666_27 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 402.0
HFD2_k127_8193666_28 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 383.0
HFD2_k127_8193666_29 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 370.0
HFD2_k127_8193666_3 acyl-CoA dehydrogenase - - - 1.633e-224 700.0
HFD2_k127_8193666_30 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 367.0
HFD2_k127_8193666_31 ABC transporter, periplasmic binding protein, thiB subfamily K02064 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 371.0
HFD2_k127_8193666_32 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 369.0
HFD2_k127_8193666_33 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 355.0
HFD2_k127_8193666_34 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009127 357.0
HFD2_k127_8193666_35 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 341.0
HFD2_k127_8193666_36 mandelate racemase muconate lactonizing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 340.0
HFD2_k127_8193666_37 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 327.0
HFD2_k127_8193666_38 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007161 325.0
HFD2_k127_8193666_39 inositol monophosphatase K01092,K05602 - 3.1.3.15,3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007503 322.0
HFD2_k127_8193666_4 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 2.904e-222 694.0
HFD2_k127_8193666_40 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 307.0
HFD2_k127_8193666_41 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 309.0
HFD2_k127_8193666_42 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006003 297.0
HFD2_k127_8193666_43 NifU-like domain K07400 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009853 293.0
HFD2_k127_8193666_44 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006513 285.0
HFD2_k127_8193666_45 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000229 299.0
HFD2_k127_8193666_46 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007484 291.0
HFD2_k127_8193666_47 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001383 278.0
HFD2_k127_8193666_48 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003534 275.0
HFD2_k127_8193666_49 PAC2 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003189 289.0
HFD2_k127_8193666_5 Putative modulator of DNA gyrase K03568 - - 5.061e-220 690.0
HFD2_k127_8193666_50 Protein of unknown function (DUF459) K09795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005861 271.0
HFD2_k127_8193666_51 dTDP-4-dehydrorhamnose reductase activity K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000618 269.0
HFD2_k127_8193666_52 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000008109 261.0
HFD2_k127_8193666_53 - K08641 - 3.4.13.22 0.000000000000000000000000000000000000000000000000000000000000000000000000005098 266.0
HFD2_k127_8193666_54 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000007044 266.0
HFD2_k127_8193666_55 PaaX-like protein K02616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001604 266.0
HFD2_k127_8193666_56 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000000000000000000000000000000000000000000002577 257.0
HFD2_k127_8193666_57 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000006315 250.0
HFD2_k127_8193666_58 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000001005 241.0
HFD2_k127_8193666_59 Belongs to the ABC transporter superfamily K02052,K02062 - - 0.00000000000000000000000000000000000000000000000000000000000000001858 230.0
HFD2_k127_8193666_6 Peptidase family M1 domain K08776 - - 5.575e-218 704.0
HFD2_k127_8193666_60 - K09957 - - 0.0000000000000000000000000000000000000000000000000000000000000001425 240.0
HFD2_k127_8193666_61 PFAM OsmC family protein K04063 - - 0.000000000000000000000000000000000000000000000000000000000000009439 218.0
HFD2_k127_8193666_62 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000006163 205.0
HFD2_k127_8193666_63 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000002917 198.0
HFD2_k127_8193666_64 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000003817 213.0
HFD2_k127_8193666_65 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000001008 198.0
HFD2_k127_8193666_66 CopC domain K07156,K14166 - - 0.0000000000000000000000000000000000000000002205 180.0
HFD2_k127_8193666_67 Cobinamide kinase / cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000004707 162.0
HFD2_k127_8193666_68 Mycothiol maleylpyruvate isomerase N-terminal domain K16163 - 5.2.1.4 0.0000000000000000000000000000000000000001266 158.0
HFD2_k127_8193666_69 PHP-associated - - - 0.0000000000000000000000000000000000000006372 158.0
HFD2_k127_8193666_7 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 1.717e-210 668.0
HFD2_k127_8193666_70 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000006054 161.0
HFD2_k127_8193666_71 helix_turn_helix ASNC type K03718 - - 0.0000000000000000000000000000000001673 139.0
HFD2_k127_8193666_72 Major facilitator Superfamily - - - 0.000000000000000000000000000000003777 144.0
HFD2_k127_8193666_73 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000002948 131.0
HFD2_k127_8193666_75 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000001046 135.0
HFD2_k127_8193666_76 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000002209 127.0
HFD2_k127_8193666_77 PFAM oxidoreductase domain protein K19181 - 1.1.1.292 0.0000000000000000000000003503 118.0
HFD2_k127_8193666_79 Luciferase-like monooxygenase - - - 0.000000000000000000000001589 111.0
HFD2_k127_8193666_8 Putative modulator of DNA gyrase K03592 - - 1.873e-210 662.0
HFD2_k127_8193666_80 PFAM Thiamin pyrophosphokinase, vitamin B1 binding domain K00949 - 2.7.6.2 0.00000000000000000000000629 109.0
HFD2_k127_8193666_81 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000006438 106.0
HFD2_k127_8193666_82 Regulatory protein, FmdB family - - - 0.00000000000000000000009116 101.0
HFD2_k127_8193666_84 Serine aminopeptidase, S33 K16050 - 3.7.1.17 0.0000000000000000004814 102.0
HFD2_k127_8193666_85 Putative adhesin - - - 0.00000000000000000331 94.0
HFD2_k127_8193666_86 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.000000000000000286 89.0
HFD2_k127_8193666_87 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000002653 91.0
HFD2_k127_8193666_88 universal stress protein - - - 0.00000000000008173 79.0
HFD2_k127_8193666_89 Protein conserved in bacteria - - - 0.0000000000001341 77.0
HFD2_k127_8193666_9 phosphoglucomutase phosphomannomutase alpha beta alpha domain II K01835,K01840 - 5.4.2.2,5.4.2.8 1.264e-201 645.0
HFD2_k127_8193666_90 AAA ATPase domain - - - 0.000000000001145 82.0
HFD2_k127_8193666_91 protein encoded in hypervariable junctions of pilus gene clusters - - - 0.000000006103 63.0
HFD2_k127_8193666_92 4-Hydroxyphenylpyruvate dioxygenase K05606,K17315 - 5.1.99.1 0.000006315 55.0
HFD2_k127_8193666_93 Ppx/GppA phosphatase family - - - 0.00001286 48.0
HFD2_k127_8193666_94 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768,K09565 - 5.2.1.8 0.00001359 57.0
HFD2_k127_8193666_95 Psort location Cytoplasmic, score - - - 0.00003383 56.0
HFD2_k127_8266498_0 Phage tail sheath C-terminal domain K06907 - - 6.351e-243 762.0
HFD2_k127_8266498_1 Baseplate J-like protein - - - 7.428e-242 763.0
HFD2_k127_8266498_10 - - - - 0.00000000000000000000000000000000000000000000000000002245 191.0
HFD2_k127_8266498_11 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000000000001299 186.0
HFD2_k127_8266498_12 Gene 25-like lysozyme K06903 - - 0.000000000000000000000000000000000000000000000000003656 184.0
HFD2_k127_8266498_14 Domain of unknown function (DUF4280) - - - 0.0000000000000000000000000000000000000000000007399 169.0
HFD2_k127_8266498_15 PFAM Peptidoglycan-binding - - - 0.000000000000000000000000000000000000006738 153.0
HFD2_k127_8266498_16 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000000002929 144.0
HFD2_k127_8266498_17 phage tail protein - - - 0.000000000000000000000000000000001271 137.0
HFD2_k127_8266498_18 Domain of unknown function (DUF4157) - - - 0.00000000000000000000000006535 125.0
HFD2_k127_8266498_19 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000007939 118.0
HFD2_k127_8266498_2 Phage late control gene D protein (GPD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 566.0
HFD2_k127_8266498_20 Protein of unknown function (DUF4255) - - - 0.0000000000000000000003642 105.0
HFD2_k127_8266498_21 exo-alpha-(2->6)-sialidase activity K01730,K12373 - 3.2.1.52,4.2.2.6 0.000000000000000001008 102.0
HFD2_k127_8266498_22 - - - - 0.0000000001217 63.0
HFD2_k127_8266498_23 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0003655 51.0
HFD2_k127_8266498_3 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 538.0
HFD2_k127_8266498_4 PFAM transcriptional regulator domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004658 407.0
HFD2_k127_8266498_5 cell adhesion involved in biofilm formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001065 262.0
HFD2_k127_8266498_6 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000477 231.0
HFD2_k127_8266498_7 Phage tail protein (Tail_P2_I) - - - 0.000000000000000000000000000000000000000000000000000000000000001314 225.0
HFD2_k127_8266498_8 Zinc finger domain - - - 0.0000000000000000000000000000000000000000000000000000000000021 233.0
HFD2_k127_8266498_9 Glycosylase K05522 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000001628 200.0
HFD2_k127_8591030_0 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 2.904e-207 654.0
HFD2_k127_8591030_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 510.0
HFD2_k127_8591030_2 P-aminobenzoate N-oxygenase AurF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 509.0
HFD2_k127_8591030_3 Rieske 2Fe-2S - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 414.0
HFD2_k127_8591030_4 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 310.0
HFD2_k127_8591030_5 NADPH:quinone reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002113 266.0
HFD2_k127_8591030_6 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000009755 93.0
HFD2_k127_896559_0 AMP-forming long-chain acyl-CoA synthetase K01897 - 6.2.1.3 2.779e-245 777.0
HFD2_k127_896559_1 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 608.0
HFD2_k127_896559_10 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 362.0
HFD2_k127_896559_11 F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 354.0
HFD2_k127_896559_12 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007163 340.0
HFD2_k127_896559_13 pfam abc K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 339.0
HFD2_k127_896559_14 PFAM Bacterial regulatory protein, arsR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 309.0
HFD2_k127_896559_15 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 290.0
HFD2_k127_896559_16 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007252 293.0
HFD2_k127_896559_17 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000277 267.0
HFD2_k127_896559_18 Enoyl-CoA hydratase/isomerase K01692,K07546 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000006998 260.0
HFD2_k127_896559_19 Ankyrin repeats (3 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002082 253.0
HFD2_k127_896559_2 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 604.0
HFD2_k127_896559_20 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000002365 192.0
HFD2_k127_896559_21 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000006058 192.0
HFD2_k127_896559_22 pyridoxamine 5-phosphate - - - 0.000000000000000000000000000000000000000000000001058 184.0
HFD2_k127_896559_23 Beta-lactamase K01286 - 3.4.16.4 0.00000000000000000000000000000000000000532 164.0
HFD2_k127_896559_25 short-chain dehydrogenase - - - 0.00000000000000000000000000361 112.0
HFD2_k127_896559_27 lactoylglutathione lyase activity - - - 0.00000000000000000001209 96.0
HFD2_k127_896559_3 Belongs to the thiolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 484.0
HFD2_k127_896559_4 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 471.0
HFD2_k127_896559_5 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 441.0
HFD2_k127_896559_6 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 416.0
HFD2_k127_896559_7 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 398.0
HFD2_k127_896559_8 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 389.0
HFD2_k127_896559_9 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 368.0
HFD2_k127_942632_0 indolepyruvate ferredoxin oxidoreductase K00179,K04090 - 1.2.7.8 7.743e-310 985.0
HFD2_k127_942632_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 2.838e-301 948.0
HFD2_k127_942632_10 Acetyl propionyl-CoA carboxylase, alpha subunit K01959,K01965,K01968 - 6.4.1.1,6.4.1.3,6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006631 586.0
HFD2_k127_942632_11 COGs COG0620 Methionine synthase II (cobalamin-independent) K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 542.0
HFD2_k127_942632_12 Acyclic terpene utilisation family protein AtuA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 544.0
HFD2_k127_942632_13 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 531.0
HFD2_k127_942632_14 4-hydroxybenzoate K00481 - 1.14.13.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 505.0
HFD2_k127_942632_15 Protein synonym acyl-CoA synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007001 504.0
HFD2_k127_942632_16 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 431.0
HFD2_k127_942632_17 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 394.0
HFD2_k127_942632_18 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 371.0
HFD2_k127_942632_19 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 368.0
HFD2_k127_942632_2 helicase K03722 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.4.12 1.275e-246 776.0
HFD2_k127_942632_20 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 347.0
HFD2_k127_942632_21 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000417 342.0
HFD2_k127_942632_22 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 334.0
HFD2_k127_942632_23 protocatechuate 3,4-dioxygenase activity K00449 - 1.13.11.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 326.0
HFD2_k127_942632_24 ANTAR K22010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 303.0
HFD2_k127_942632_25 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 303.0
HFD2_k127_942632_26 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 288.0
HFD2_k127_942632_27 methyltransferase K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004428 298.0
HFD2_k127_942632_28 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000347 240.0
HFD2_k127_942632_29 - - - - 0.0000000000000000000000000000000000000000000000000000000000000035 229.0
HFD2_k127_942632_3 Carboxyl transferase domain - - - 2.168e-244 779.0
HFD2_k127_942632_30 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07684 - - 0.000000000000000000000000000000000000000000000000000000000000004046 222.0
HFD2_k127_942632_31 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000005225 219.0
HFD2_k127_942632_32 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000003139 215.0
HFD2_k127_942632_33 3-oxoadipate enol-lactonase K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000004697 223.0
HFD2_k127_942632_34 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000003086 213.0
HFD2_k127_942632_35 Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant K06720 - 4.2.1.108 0.00000000000000000000000000000000000000000000000000000000124 202.0
HFD2_k127_942632_36 FabA-like domain K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000007102 208.0
HFD2_k127_942632_37 Dioxygenase K00448 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000006559 197.0
HFD2_k127_942632_38 oxidation-reduction process K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000004594 184.0
HFD2_k127_942632_39 phosphorelay sensor kinase activity K03406,K07673,K07675 - 2.7.13.3 0.0000000000000000000000000000000000000000000004482 189.0
HFD2_k127_942632_4 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 2.076e-240 747.0
HFD2_k127_942632_40 Lyase K01857 - 5.5.1.2 0.0000000000000000000000000000000000000005908 162.0
HFD2_k127_942632_41 transferase activity, transferring alkyl or aryl (other than methyl) groups K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000006871 149.0
HFD2_k127_942632_42 Acetyltransferase (GNAT) domain K00663,K03790 - 2.3.1.128,2.3.1.82 0.00000000000000000000000000000000001577 142.0
HFD2_k127_942632_43 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000003777 118.0
HFD2_k127_942632_44 Protein of unknown function (DUF1810) - - - 0.0000000000000000000000000003827 120.0
HFD2_k127_942632_45 fatty acid desaturase transmembrane protein - - - 0.000000000000000000000006514 116.0
HFD2_k127_942632_46 PFAM regulatory protein, MarR - - - 0.000000000000000000003298 99.0
HFD2_k127_942632_47 - - - - 0.000000000000000001188 89.0
HFD2_k127_942632_49 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000004591 56.0
HFD2_k127_942632_5 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K03520 - 1.2.5.3 3.433e-220 708.0
HFD2_k127_942632_6 Ribosomal protein S1-like RNA-binding domain K02945 - - 3.044e-219 688.0
HFD2_k127_942632_7 4-hydroxyphenylacetate 3-monooxygenase oxygenase K00483 - 1.14.14.9 1.165e-216 685.0
HFD2_k127_942632_8 Acyl transferase domain K00645 - 2.3.1.39 4.37e-198 622.0
HFD2_k127_942632_9 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 5.713e-198 621.0
HFD2_k127_985780_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 2.511e-240 749.0
HFD2_k127_985780_1 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 596.0
HFD2_k127_985780_2 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 376.0
HFD2_k127_985780_3 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001663 274.0
HFD2_k127_985780_4 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000005883 263.0