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Overview

ID MAG01644
Name HFD2_bin.32
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Polarisedimenticolia
Order Gp22-AA2
Family Gp22-AA2
Genus DATKFL01
Species
Assembly information
Completeness (%) 89.8
Contamination (%) 3.02
GC content (%) 72.0
N50 (bp) 35,012
Genome size (bp) 4,537,636

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3482

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_1081677_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 357.0
HFD2_k127_1081677_1 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000001109 212.0
HFD2_k127_1081677_2 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000001729 198.0
HFD2_k127_1081677_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000003393 197.0
HFD2_k127_1137247_0 Amidohydrolase family - - - 4.735e-223 706.0
HFD2_k127_1137247_1 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 563.0
HFD2_k127_1137247_10 Pfam Cupin - - - 0.00000000000000000000000000000000000000000000000000000005224 201.0
HFD2_k127_1137247_11 membrane - - - 0.000000000000000000000000000000000000000001837 164.0
HFD2_k127_1137247_12 SMART Tetratricopeptide domain protein - - - 0.00000000000000000000000000000000000001597 154.0
HFD2_k127_1137247_13 - - - - 0.0000000000000000000000000000000000003296 145.0
HFD2_k127_1137247_14 Protein of unknown function (DUF2442) - - - 0.0000000000000000000000000001146 118.0
HFD2_k127_1137247_15 - - - - 0.0000000000000000000000000004797 120.0
HFD2_k127_1137247_16 COG0457 FOG TPR repeat - - - 0.00000000000000000000000004937 120.0
HFD2_k127_1137247_17 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000000133 106.0
HFD2_k127_1137247_18 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000004187 119.0
HFD2_k127_1137247_19 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000000000006435 106.0
HFD2_k127_1137247_2 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008604 465.0
HFD2_k127_1137247_20 - - - - 0.000000000000000000000002342 106.0
HFD2_k127_1137247_21 COG3209 Rhs family protein - - - 0.0000000000000000000001272 117.0
HFD2_k127_1137247_22 TIGRFAM YD repeat protein - - - 0.000000000000000000003411 113.0
HFD2_k127_1137247_23 Tetratricopeptide repeat - - - 0.00000000000000000001484 101.0
HFD2_k127_1137247_24 Protein of unknown function (DUF433) - - - 0.000000000000007306 78.0
HFD2_k127_1137247_26 - - - - 0.0000000000004346 71.0
HFD2_k127_1137247_27 TPR repeat - - - 0.000000000002839 78.0
HFD2_k127_1137247_28 Domain of unknown function (DUF1707) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000005178 70.0
HFD2_k127_1137247_29 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000001529 66.0
HFD2_k127_1137247_3 helicase superfamily c-terminal domain K05592 GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 328.0
HFD2_k127_1137247_30 Pectinesterase K01051 - 3.1.1.11 0.000000004731 72.0
HFD2_k127_1137247_31 cell adhesion - - - 0.00000001843 67.0
HFD2_k127_1137247_32 PFAM transposase IS3 IS911 family protein K07483 - - 0.0000002637 54.0
HFD2_k127_1137247_35 Putative zinc-finger - - - 0.00006843 55.0
HFD2_k127_1137247_36 Tetratricopeptide repeat - - - 0.0001493 55.0
HFD2_k127_1137247_4 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 287.0
HFD2_k127_1137247_5 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001023 277.0
HFD2_k127_1137247_6 excinuclease ABC activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005375 248.0
HFD2_k127_1137247_7 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000008325 238.0
HFD2_k127_1137247_8 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003584 249.0
HFD2_k127_1137247_9 SnoaL-like domain K06893 - - 0.000000000000000000000000000000000000000000000000000000001522 203.0
HFD2_k127_1164830_0 AcrB/AcrD/AcrF family - - - 0.0 1141.0
HFD2_k127_1164830_1 metalloendopeptidase activity K01283 - 3.4.15.1 1.539e-258 810.0
HFD2_k127_1164830_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000002801 187.0
HFD2_k127_1164830_11 Protease prsW family - - - 0.0000000000000000000000000000000001347 145.0
HFD2_k127_1164830_12 SWI complex, BAF60b domains - - - 0.000000000000000000000000000000164 126.0
HFD2_k127_1164830_13 Yip1 domain - - - 0.0000000000000000000000000001203 126.0
HFD2_k127_1164830_14 PFAM peptidase S1 and S6 chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000002127 128.0
HFD2_k127_1164830_15 - - - - 0.00000000000000000000000001547 126.0
HFD2_k127_1164830_17 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000139 106.0
HFD2_k127_1164830_18 cell redox homeostasis K03671 - - 0.00000000000000000005944 104.0
HFD2_k127_1164830_19 Thioredoxin - - - 0.0000000000000000001855 103.0
HFD2_k127_1164830_2 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00146,K10217 - 1.2.1.3,1.2.1.32,1.2.1.39,1.2.1.8,1.2.1.85 4.048e-211 682.0
HFD2_k127_1164830_20 Outer membrane efflux protein - - - 0.0000000000000000101 97.0
HFD2_k127_1164830_21 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000005133 79.0
HFD2_k127_1164830_22 Protein of unknown function (DUF2892) - - - 0.000000000005968 76.0
HFD2_k127_1164830_23 anti-sigma regulatory factor K04757 - 2.7.11.1 0.00000000002262 70.0
HFD2_k127_1164830_25 methyltransferase - - - 0.0000000006626 70.0
HFD2_k127_1164830_26 - - - - 0.0000002715 60.0
HFD2_k127_1164830_27 Lytic transglycosylase catalytic K08309 - - 0.000008374 59.0
HFD2_k127_1164830_28 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00001043 51.0
HFD2_k127_1164830_29 - - - - 0.0002214 49.0
HFD2_k127_1164830_3 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 441.0
HFD2_k127_1164830_4 acyl-coa dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 437.0
HFD2_k127_1164830_5 FAD binding domain K00103,K00279 - 1.1.3.8,1.5.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 320.0
HFD2_k127_1164830_6 peptidase dimerisation domain protein K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000009917 268.0
HFD2_k127_1164830_7 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000003014 248.0
HFD2_k127_1164830_8 C-terminal domain of alpha-glycerophosphate oxidase K00111 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 1.1.5.3 0.0000000000000000000000000000000000000000000000000515 183.0
HFD2_k127_1164830_9 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000000000000000000004553 186.0
HFD2_k127_1168544_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001264 261.0
HFD2_k127_1168544_1 spore germination K07790 - - 0.000000000000000000000000000000000000000000000003496 193.0
HFD2_k127_1168544_2 - - - - 0.0000000000000000000000006288 115.0
HFD2_k127_1168544_3 PFAM Excinuclease ABC, C subunit domain protein K07461 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.00000000000000005111 93.0
HFD2_k127_1168544_4 aminopeptidase N - - - 0.000000000000000464 88.0
HFD2_k127_1168544_5 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000001214 76.0
HFD2_k127_1178109_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 - 1.17.1.4 2.724e-198 643.0
HFD2_k127_1178109_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 398.0
HFD2_k127_1178109_10 2Fe-2S -binding K13483 - - 0.0000000000000000000000000000000000000000000000000000000000261 212.0
HFD2_k127_1178109_11 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000000000000000000000000000001964 133.0
HFD2_k127_1178109_12 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000001447 116.0
HFD2_k127_1178109_13 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000009775 106.0
HFD2_k127_1178109_14 regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000001357 118.0
HFD2_k127_1178109_15 - - - - 0.00000000000004372 81.0
HFD2_k127_1178109_16 CAAX protease self-immunity K07052 - - 0.0000000003842 71.0
HFD2_k127_1178109_17 Beta-xylanase K01181 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010383,GO:0010410,GO:0016052,GO:0016787,GO:0016798,GO:0030312,GO:0031176,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0045491,GO:0045493,GO:0071554,GO:0071704,GO:0071944,GO:0097599,GO:1901575 3.2.1.8 0.000000004475 70.0
HFD2_k127_1178109_18 Belongs to the peptidase M10A family K01402,K07999,K08004 - 3.4.24.34 0.000001761 58.0
HFD2_k127_1178109_19 guanyl-nucleotide exchange factor activity K01183,K12287 - 3.2.1.14 0.000004393 61.0
HFD2_k127_1178109_2 TIGRFAM cysteine desulfurase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000705 393.0
HFD2_k127_1178109_20 peptidase M4 thermolysin K01400 - 3.4.24.28 0.000007621 56.0
HFD2_k127_1178109_3 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 381.0
HFD2_k127_1178109_4 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 319.0
HFD2_k127_1178109_5 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 307.0
HFD2_k127_1178109_6 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000001224 267.0
HFD2_k127_1178109_7 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002914 269.0
HFD2_k127_1178109_8 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000001199 258.0
HFD2_k127_1178109_9 Histidine kinase-like ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008236 263.0
HFD2_k127_1252433_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 614.0
HFD2_k127_1252433_1 Uncharacterized protein family UPF0029 - - - 0.000000000000000000000002727 110.0
HFD2_k127_1252433_2 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000001799 94.0
HFD2_k127_1258755_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000004894 194.0
HFD2_k127_1258755_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000003182 172.0
HFD2_k127_1258755_2 Ankyrin repeat - - - 0.00000000000000000000000000000000005743 141.0
HFD2_k127_1258755_3 Lysin motif - - - 0.000000000000000000000000000000001504 143.0
HFD2_k127_1258755_4 Peptidase S15 K06978 - - 0.000000000000000000107 95.0
HFD2_k127_1263381_0 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0 1286.0
HFD2_k127_1263381_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.894e-264 835.0
HFD2_k127_1263381_10 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 431.0
HFD2_k127_1263381_11 Bacterial extracellular solute-binding protein K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 445.0
HFD2_k127_1263381_12 Chalcone and stilbene synthases, C-terminal domain K16167,K19580 - 2.3.1.233 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 428.0
HFD2_k127_1263381_13 Biotin-lipoyl like K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 414.0
HFD2_k127_1263381_14 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 399.0
HFD2_k127_1263381_15 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 405.0
HFD2_k127_1263381_16 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006309 416.0
HFD2_k127_1263381_17 sulfate ABC transporter K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 366.0
HFD2_k127_1263381_18 ABC-2 type transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 353.0
HFD2_k127_1263381_19 COG0555 ABC-type sulfate transport system, permease component K02046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 347.0
HFD2_k127_1263381_2 Prokaryotic cytochrome b561 - - - 1.171e-246 780.0
HFD2_k127_1263381_20 Phosphate-selective porin O and P K07221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 354.0
HFD2_k127_1263381_21 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 344.0
HFD2_k127_1263381_22 major pilin protein fima - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007267 336.0
HFD2_k127_1263381_23 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009594 321.0
HFD2_k127_1263381_24 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 316.0
HFD2_k127_1263381_25 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 299.0
HFD2_k127_1263381_26 PFAM SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003082 271.0
HFD2_k127_1263381_27 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001656 269.0
HFD2_k127_1263381_28 Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009951 246.0
HFD2_k127_1263381_29 Sterol-sensing domain of SREBP cleavage-activation K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000003071 256.0
HFD2_k127_1263381_3 Tetratricopeptide repeat K12132 - 2.7.11.1 9.027e-220 710.0
HFD2_k127_1263381_30 Pfam Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000005574 226.0
HFD2_k127_1263381_31 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000002934 222.0
HFD2_k127_1263381_32 endonuclease activity K07451 - - 0.00000000000000000000000000000000000000000000000000002171 213.0
HFD2_k127_1263381_33 Isoprenylcysteine carboxyl methyltransferase K16168 - - 0.00000000000000000000000000000000000000000000000000006692 198.0
HFD2_k127_1263381_34 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.000000000000000000000000000000000000000000000000005296 191.0
HFD2_k127_1263381_35 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000007042 199.0
HFD2_k127_1263381_36 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.0000000000000000000000000000000000000000000002316 176.0
HFD2_k127_1263381_37 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000006078 178.0
HFD2_k127_1263381_38 Response regulator receiver - - - 0.00000000000000000000000000000000000000000007314 171.0
HFD2_k127_1263381_39 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000004219 162.0
HFD2_k127_1263381_4 PFAM peptidase M3A and M3B thimet oligopeptidase F K08602 - - 1.315e-198 637.0
HFD2_k127_1263381_40 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000001138 154.0
HFD2_k127_1263381_41 - - - - 0.0000000000000000000000000002927 120.0
HFD2_k127_1263381_42 nitric oxide dioxygenase activity - - - 0.0000000000000000000000006745 109.0
HFD2_k127_1263381_43 Cytidylate kinase-like family - - - 0.000000000000000000000002372 112.0
HFD2_k127_1263381_44 PFAM Ion transport 2 - - - 0.000000000000000000000002635 111.0
HFD2_k127_1263381_45 response regulator, receiver - - - 0.000000000000000007981 87.0
HFD2_k127_1263381_46 - - - - 0.00000000000000009895 93.0
HFD2_k127_1263381_47 - - - - 0.00000000001372 78.0
HFD2_k127_1263381_48 Uncharacterized small protein (DUF2292) - - - 0.00000001613 60.0
HFD2_k127_1263381_49 amine dehydrogenase activity K20276 - - 0.00004094 54.0
HFD2_k127_1263381_5 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 619.0
HFD2_k127_1263381_50 Saccharopine dehydrogenase NADP binding domain - - - 0.000189 55.0
HFD2_k127_1263381_6 ATPase activity K02045 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006974 601.0
HFD2_k127_1263381_7 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 591.0
HFD2_k127_1263381_8 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 496.0
HFD2_k127_1263381_9 His Kinase A (phosphoacceptor) domain K07641,K10819 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008576 455.0
HFD2_k127_1265724_0 Prolyl oligopeptidase family - - - 2.038e-252 799.0
HFD2_k127_1265724_1 ASPIC and UnbV - - - 1.697e-196 628.0
HFD2_k127_1265724_2 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 376.0
HFD2_k127_1265724_3 COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 341.0
HFD2_k127_1265724_4 Belongs to the peptidase S51 family K05995 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 0.00000000000000000000000000000000000000000000000000000000000000000000000007117 261.0
HFD2_k127_1265724_5 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000121 240.0
HFD2_k127_1265724_6 OsmC-like protein K04063 - - 0.0000000000000000000000000000000001976 147.0
HFD2_k127_1265724_7 Tellurite resistance protein TehB - - - 0.000000000000000000000000002739 130.0
HFD2_k127_1265724_8 oligosaccharyl transferase activity - - - 0.00000000000000000000000007391 124.0
HFD2_k127_1265724_9 ThiF family K21029,K21147 - 2.7.7.80,2.8.1.11 0.00000001268 68.0
HFD2_k127_133262_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1045.0
HFD2_k127_133262_1 Carbon starvation protein K06200 - - 1.168e-223 711.0
HFD2_k127_133262_10 MgtC family K07507 - - 0.000000000000000000000000000000000004937 150.0
HFD2_k127_133262_11 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000003144 132.0
HFD2_k127_133262_12 ABC transporter substrate-binding protein K01989 - - 0.0000000000008918 80.0
HFD2_k127_133262_13 Acetyltransferase (GNAT) domain - - - 0.000002505 57.0
HFD2_k127_133262_14 CarboxypepD_reg-like domain - - - 0.0005698 52.0
HFD2_k127_133262_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 9.386e-216 679.0
HFD2_k127_133262_3 peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 537.0
HFD2_k127_133262_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 445.0
HFD2_k127_133262_5 SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 398.0
HFD2_k127_133262_6 Belongs to the peptidase S1C family K04691,K04771,K04772 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 330.0
HFD2_k127_133262_7 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000119 203.0
HFD2_k127_133262_8 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000000003063 187.0
HFD2_k127_133262_9 Bacterial DNA polymerase III alpha subunit K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0000000000000000000000000000000000000000000002605 179.0
HFD2_k127_1347139_0 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 569.0
HFD2_k127_1347139_1 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000003518 234.0
HFD2_k127_1347139_2 PFAM homoserine dehydrogenase K00003,K12524 - 1.1.1.3,2.7.2.4 0.00000000000000000000000000000000000000000000000000000000567 211.0
HFD2_k127_1456538_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 6.058e-263 825.0
HFD2_k127_1456538_1 DNA helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 598.0
HFD2_k127_1456538_2 Tetratricopeptide TPR_2 repeat protein - - - 0.0002191 55.0
HFD2_k127_1531071_0 lysine 2,3-aminomutase K01843 - 5.4.3.2 1.349e-246 769.0
HFD2_k127_1531071_1 formate dehydrogenase - - - 3.022e-244 777.0
HFD2_k127_1531071_10 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000705 227.0
HFD2_k127_1531071_11 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000003118 215.0
HFD2_k127_1531071_13 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000006066 205.0
HFD2_k127_1531071_14 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.00000000000000000000000000000000000000000000000008038 192.0
HFD2_k127_1531071_15 Cytochrome b/b6/petB K00412,K03888 - - 0.000000000000000000000000000000000000000001039 171.0
HFD2_k127_1531071_16 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) - - - 0.0000000000000000000000000000000000000002356 154.0
HFD2_k127_1531071_17 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000002041 164.0
HFD2_k127_1531071_18 amine dehydrogenase activity K21449 - - 0.000000000000000000000000000000000002618 151.0
HFD2_k127_1531071_19 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.00000000000000000000000000001972 126.0
HFD2_k127_1531071_2 peptidyl-tyrosine sulfation - - - 1.366e-236 750.0
HFD2_k127_1531071_20 PFAM sodium K14445 - - 0.000000000000000000009568 107.0
HFD2_k127_1531071_21 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.000000000000000009943 92.0
HFD2_k127_1531071_22 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000006492 77.0
HFD2_k127_1531071_23 Lipid A 3-O-deacylase (PagL) - - - 0.0000000002686 73.0
HFD2_k127_1531071_24 Tetratricopeptide repeat - - - 0.000009751 59.0
HFD2_k127_1531071_25 PFAM IstB domain protein ATP-binding protein - - - 0.00003421 49.0
HFD2_k127_1531071_26 COGs COG4633 conserved - - - 0.00004968 51.0
HFD2_k127_1531071_27 Glycosyl transferase family 41 - - - 0.0007296 53.0
HFD2_k127_1531071_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 576.0
HFD2_k127_1531071_4 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 432.0
HFD2_k127_1531071_5 denitrification pathway K02569,K15876 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 366.0
HFD2_k127_1531071_6 Cytochrome c554 and c-prime K03620 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 354.0
HFD2_k127_1531071_7 histidine kinase A domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009561 310.0
HFD2_k127_1531071_8 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006749 291.0
HFD2_k127_1531071_9 Fe-S oxidoreductases K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002342 251.0
HFD2_k127_1710563_0 Prolyl oligopeptidase K01322 - 3.4.21.26 1.728e-281 895.0
HFD2_k127_1710563_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007766 607.0
HFD2_k127_1710563_10 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000001651 224.0
HFD2_k127_1710563_11 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000208 185.0
HFD2_k127_1710563_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000001518 159.0
HFD2_k127_1710563_13 - - - - 0.00000000000000000000000000000000000000004295 156.0
HFD2_k127_1710563_14 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000004225 142.0
HFD2_k127_1710563_15 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000002357 119.0
HFD2_k127_1710563_16 PFAM NIPSNAP family containing protein - - - 0.00000000000000000002837 104.0
HFD2_k127_1710563_17 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000571 85.0
HFD2_k127_1710563_18 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000009946 78.0
HFD2_k127_1710563_19 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.00006845 52.0
HFD2_k127_1710563_2 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 587.0
HFD2_k127_1710563_20 OmpA family K03286 - - 0.0007745 42.0
HFD2_k127_1710563_21 Protein of unknown function (DUF2959) - - - 0.000955 49.0
HFD2_k127_1710563_22 Zinc-finger domain of monoamine-oxidase A repressor R1 - - - 0.0009866 50.0
HFD2_k127_1710563_3 PFAM Peptidase M16 inactive domain K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829 452.0
HFD2_k127_1710563_4 aminopeptidase activity K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 421.0
HFD2_k127_1710563_5 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 399.0
HFD2_k127_1710563_6 Peptidase, M16 K07263,K07623 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499 409.0
HFD2_k127_1710563_7 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008482 340.0
HFD2_k127_1710563_8 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 289.0
HFD2_k127_1710563_9 ornithine cyclodeaminase activity K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000001666 242.0
HFD2_k127_1726503_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 594.0
HFD2_k127_1726503_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 491.0
HFD2_k127_1726503_10 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000001948 231.0
HFD2_k127_1726503_11 PFAM HhH-GPD family protein K07457 - - 0.0000000000000000000000000000000000000000000000000000000007641 209.0
HFD2_k127_1726503_12 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000001427 213.0
HFD2_k127_1726503_13 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000009472 202.0
HFD2_k127_1726503_14 Bacterial Ig-like domain (group 3) - - - 0.000000000000000000000000000000000000000000000001271 202.0
HFD2_k127_1726503_15 Histidine kinase - - - 0.000000000000000000000000000000000000000000002202 178.0
HFD2_k127_1726503_16 LytTr DNA-binding domain K02477,K07705,K21696 GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - 0.000000000000000000000000000000000000000004399 167.0
HFD2_k127_1726503_17 OsmC-like protein K07397 - - 0.00000000000000000000000000000000000003089 159.0
HFD2_k127_1726503_18 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000001206 158.0
HFD2_k127_1726503_19 peroxiredoxin activity K02199 - - 0.00000000000000000000000000000001777 141.0
HFD2_k127_1726503_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 474.0
HFD2_k127_1726503_20 Belongs to the peptidase S1C family - - - 0.000000000000000000000000000003337 138.0
HFD2_k127_1726503_21 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000004541 124.0
HFD2_k127_1726503_22 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000003719 130.0
HFD2_k127_1726503_23 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000007683 119.0
HFD2_k127_1726503_24 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000001696 117.0
HFD2_k127_1726503_25 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K04772 - 3.4.21.107 0.00000000000000000000001374 116.0
HFD2_k127_1726503_26 CarboxypepD_reg-like domain - - - 0.0000000000000000061 100.0
HFD2_k127_1726503_27 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000003439 96.0
HFD2_k127_1726503_28 Domain of unknown function (DUF4440) - - - 0.0000000000000001144 86.0
HFD2_k127_1726503_29 Thrombospondin C-terminal region K16857 GO:0000187,GO:0000302,GO:0001501,GO:0001525,GO:0001568,GO:0001666,GO:0001786,GO:0001817,GO:0001818,GO:0001819,GO:0001932,GO:0001934,GO:0001936,GO:0001937,GO:0001944,GO:0001952,GO:0001953,GO:0001968,GO:0002040,GO:0002376,GO:0002544,GO:0002576,GO:0002577,GO:0002578,GO:0002580,GO:0002581,GO:0002604,GO:0002605,GO:0002682,GO:0002683,GO:0002684,GO:0002685,GO:0002687,GO:0002688,GO:0002690,GO:0002694,GO:0002696,GO:0003007,GO:0003151,GO:0003197,GO:0003416,GO:0003417,GO:0003674,GO:0005102,GO:0005178,GO:0005488,GO:0005509,GO:0005515,GO:0005518,GO:0005539,GO:0005543,GO:0005575,GO:0005576,GO:0005577,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005886,GO:0006417,GO:0006464,GO:0006807,GO:0006810,GO:0006887,GO:0006897,GO:0006909,GO:0006911,GO:0006928,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0006979,GO:0007049,GO:0007050,GO:0007155,GO:0007162,GO:0007275,GO:0007507,GO:0007610,GO:0008150,GO:0008152,GO:0008201,GO:0008284,GO:0008285,GO:0008289,GO:0009266,GO:0009408,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009887,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009897,GO:0009966,GO:0009967,GO:0009968,GO:0009986,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010324,GO:0010466,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010594,GO:0010595,GO:0010596,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010632,GO:0010633,GO:0010634,GO:0010646,GO:0010647,GO:0010648,GO:0010746,GO:0010748,GO:0010749,GO:0010751,GO:0010752,GO:0010754,GO:0010755,GO:0010757,GO:0010758,GO:0010759,GO:0010762,GO:0010763,GO:0010810,GO:0010811,GO:0010812,GO:0010941,GO:0010942,GO:0010951,GO:0010955,GO:0012505,GO:0014070,GO:0016020,GO:0016043,GO:0016192,GO:0016477,GO:0016525,GO:0016528,GO:0016529,GO:0017015,GO:0017134,GO:0018149,GO:0019220,GO:0019222,GO:0019538,GO:0019838,GO:0019955,GO:0022402,GO:0022603,GO:0022610,GO:0023051,GO:0023056,GO:0023057,GO:0030141,GO:0030155,GO:0030162,GO:0030169,GO:0030193,GO:0030194,GO:0030198,GO:0030334,GO:0030335,GO:0030336,GO:0030511,GO:0031012,GO:0031091,GO:0031093,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031399,GO:0031401,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032026,GO:0032101,GO:0032102,GO:0032103,GO:0032147,GO:0032268,GO:0032269,GO:0032270,GO:0032368,GO:0032369,GO:0032501,GO:0032502,GO:0032570,GO:0032655,GO:0032680,GO:0032695,GO:0032760,GO:0032879,GO:0032890,GO:0032891,GO:0032908,GO:0032914,GO:0032940,GO:0032991,GO:0033554,GO:0033555,GO:0033674,GO:0033993,GO:0034248,GO:0034250,GO:0034284,GO:0034599,GO:0034605,GO:0034614,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0034774,GO:0034976,GO:0035239,GO:0035265,GO:0035295,GO:0035690,GO:0036211,GO:0036293,GO:0040007,GO:0040011,GO:0040012,GO:0040013,GO:0040017,GO:0040036,GO:0040037,GO:0042035,GO:0042108,GO:0042127,GO:0042221,GO:0042325,GO:0042327,GO:0042493,GO:0042534,GO:0042535,GO:0042802,GO:0042981,GO:0043030,GO:0043032,GO:0043062,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043086,GO:0043154,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043236,GO:0043269,GO:0043271,GO:0043277,GO:0043281,GO:0043394,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043412,GO:0043535,GO:0043536,GO:0043537,GO:0043549,GO:0043652,GO:0044070,GO:0044087,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044877,GO:0045055,GO:0045595,GO:0045637,GO:0045652,GO:0045727,GO:0045765,GO:0045766,GO:0045785,GO:0045786,GO:0045859,GO:0045860,GO:0045861,GO:0045937,GO:0046872,GO:0046903,GO:0048265,GO:0048266,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048584,GO:0048585,GO:0048589,GO:0048646,GO:0048660,GO:0048661,GO:0048705,GO:0048731,GO:0048856,GO:0048870,GO:0050431,GO:0050678,GO:0050680,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050818,GO:0050820,GO:0050839,GO:0050840,GO:0050865,GO:0050867,GO:0050878,GO:0050896,GO:0050920,GO:0050921,GO:0050922,GO:0051049,GO:0051051,GO:0051093,GO:0051094,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051216,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051270,GO:0051271,GO:0051272,GO:0051336,GO:0051338,GO:0051346,GO:0051347,GO:0051592,GO:0051674,GO:0051716,GO:0051726,GO:0051893,GO:0051895,GO:0051896,GO:0051897,GO:0051917,GO:0051918,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060485,GO:0060548,GO:0061024,GO:0061041,GO:0061448,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070051,GO:0070052,GO:0070482,GO:0070613,GO:0070887,GO:0071241,GO:0071622,GO:0071634,GO:0071636,GO:0071675,GO:0071704,GO:0071731,GO:0071732,GO:0071813,GO:0071814,GO:0071840,GO:0071900,GO:0071902,GO:0071944,GO:0072341,GO:0072358,GO:0072359,GO:0080090,GO:0080134,GO:0090049,GO:0090051,GO:0090092,GO:0090100,GO:0090109,GO:0090287,GO:0090288,GO:0090303,GO:0097366,GO:0097367,GO:0097708,GO:0098552,GO:0098657,GO:0098868,GO:0099024,GO:0099503,GO:1900046,GO:1900048,GO:1901342,GO:1901343,GO:1901564,GO:1901654,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901888,GO:1901889,GO:1902041,GO:1902043,GO:1902170,GO:1902531,GO:1902532,GO:1902533,GO:1903034,GO:1903036,GO:1903317,GO:1903318,GO:1903391,GO:1903392,GO:1903555,GO:1903557,GO:1903587,GO:1903588,GO:1903670,GO:1903671,GO:1903706,GO:1903792,GO:1903844,GO:1903846,GO:1903959,GO:1903960,GO:1904018,GO:1904035,GO:1904037,GO:1905521,GO:1905523,GO:1905952,GO:1905953,GO:2000026,GO:2000112,GO:2000116,GO:2000117,GO:2000145,GO:2000146,GO:2000147,GO:2000181,GO:2000191,GO:2000192,GO:2000351,GO:2000353,GO:2000377,GO:2000379,GO:2001026,GO:2001027,GO:2001233,GO:2001234,GO:2001235,GO:2001236,GO:2001237,GO:2001238 - 0.0000000000000009227 93.0
HFD2_k127_1726503_3 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 475.0
HFD2_k127_1726503_30 Metallo-peptidase family M12B Reprolysin-like - - - 0.000000000000006319 91.0
HFD2_k127_1726503_31 - - - - 0.0000000000005427 75.0
HFD2_k127_1726503_33 - - - - 0.0005807 50.0
HFD2_k127_1726503_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008438 489.0
HFD2_k127_1726503_5 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004502 450.0
HFD2_k127_1726503_6 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 411.0
HFD2_k127_1726503_7 aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 341.0
HFD2_k127_1726503_8 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000414 293.0
HFD2_k127_1726503_9 COG3119 Arylsulfatase A and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000004448 245.0
HFD2_k127_1757283_0 Amino acid adenylation domain - - - 0.0 1067.0
HFD2_k127_1757283_1 Protein of unknown function (DUF2961) - - - 0.0 1039.0
HFD2_k127_1757283_10 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 415.0
HFD2_k127_1757283_11 carboxylase K01965,K01968 - 6.4.1.3,6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 402.0
HFD2_k127_1757283_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 387.0
HFD2_k127_1757283_13 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004442 358.0
HFD2_k127_1757283_14 PFAM pyruvate carboxyltransferase K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007426 331.0
HFD2_k127_1757283_15 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007983 335.0
HFD2_k127_1757283_16 PFAM Pyruvate carboxyltransferase K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007482 294.0
HFD2_k127_1757283_17 ABC transporter, ATP-binding protein K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004599 290.0
HFD2_k127_1757283_18 ABC 3 transport family K02075,K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000106 287.0
HFD2_k127_1757283_19 Arsenical pump membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009753 279.0
HFD2_k127_1757283_2 cellulose binding - - - 5.391e-309 972.0
HFD2_k127_1757283_20 enoyl-CoA hydratase K13766,K15312 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000001078 266.0
HFD2_k127_1757283_21 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000025 259.0
HFD2_k127_1757283_22 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.000000000000000000000000000000000000000000000000000000000000000004004 239.0
HFD2_k127_1757283_23 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004001 233.0
HFD2_k127_1757283_24 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000006039 220.0
HFD2_k127_1757283_25 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000001577 217.0
HFD2_k127_1757283_26 PFAM regulatory protein LuxR - - - 0.000000000000000000000000000000000000000000000000000000000009652 214.0
HFD2_k127_1757283_27 Response regulator receiver K07696 - - 0.00000000000000000000000000000000000000000000000000000005076 204.0
HFD2_k127_1757283_28 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000000000000000000000742 181.0
HFD2_k127_1757283_29 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000000001588 166.0
HFD2_k127_1757283_3 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 6.893e-233 731.0
HFD2_k127_1757283_30 anti-sigma regulatory factor K17752 - 2.7.11.1 0.0000000000000000000000000000000000000002504 155.0
HFD2_k127_1757283_31 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K17762 - - 0.0000000000000000000000000000000000006685 158.0
HFD2_k127_1757283_32 Histidine kinase - - - 0.000000000000000000000000000000000001884 157.0
HFD2_k127_1757283_33 YMGG-like Gly-zipper - - - 0.0000000000000000000000000000000002168 141.0
HFD2_k127_1757283_35 Stage II sporulation protein - - - 0.000000000000000000000000000125 130.0
HFD2_k127_1757283_36 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000002969 127.0
HFD2_k127_1757283_37 Belongs to the BolA IbaG family K05527 - - 0.000000000000000000001173 101.0
HFD2_k127_1757283_38 COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 - 6.4.1.4 0.0000000001844 74.0
HFD2_k127_1757283_39 TOBE domain - - - 0.000000009442 61.0
HFD2_k127_1757283_4 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 638.0
HFD2_k127_1757283_40 lysine biosynthetic process via aminoadipic acid K00997,K06133 - 2.7.8.7 0.00000005646 64.0
HFD2_k127_1757283_41 General secretion pathway protein G K02456 - - 0.0000006521 58.0
HFD2_k127_1757283_42 PilZ domain - - - 0.00004229 53.0
HFD2_k127_1757283_43 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0009522 52.0
HFD2_k127_1757283_5 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 475.0
HFD2_k127_1757283_6 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K17763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 423.0
HFD2_k127_1757283_7 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 425.0
HFD2_k127_1757283_8 FAD dependent oxidoreductase K00109 - 1.1.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 419.0
HFD2_k127_1757283_9 TIGRFAM oligoendopeptidase F K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 422.0
HFD2_k127_1805143_0 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 564.0
HFD2_k127_1805143_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002208 258.0
HFD2_k127_1805143_2 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000009097 231.0
HFD2_k127_1805143_3 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000002368 190.0
HFD2_k127_1805143_4 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000000006256 178.0
HFD2_k127_1805143_5 N-terminal domain of unknown function (DUF4140) - - - 0.0000000000000000000000000000000000000000007885 180.0
HFD2_k127_1805143_6 Sulfatase - - - 0.000000000164 75.0
HFD2_k127_1805143_7 deoxyhypusine monooxygenase activity - - - 0.00003423 57.0
HFD2_k127_1810488_0 Acyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 542.0
HFD2_k127_1810488_1 Acyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001027 238.0
HFD2_k127_1810977_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 4.732e-204 645.0
HFD2_k127_1810977_1 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 466.0
HFD2_k127_1810977_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000001502 121.0
HFD2_k127_1810977_3 PBS lyase HEAT-like repeat - - - 0.0000000000000000000002186 115.0
HFD2_k127_1829066_0 TRAP transporter, 4TM 12TM fusion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 389.0
HFD2_k127_1829066_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0000000000004594 71.0
HFD2_k127_1838831_0 Cytochrome C assembly protein K02198,K04016 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 617.0
HFD2_k127_1838831_1 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 495.0
HFD2_k127_1838831_10 ABC transporter K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000154 203.0
HFD2_k127_1838831_11 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.0000000000000000000000000000000000000000000006126 179.0
HFD2_k127_1838831_12 GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000001316 169.0
HFD2_k127_1838831_13 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000169 154.0
HFD2_k127_1838831_14 maturation factor XdhC CoxF family K07402 - - 0.000000000000000000000000000000007251 139.0
HFD2_k127_1838831_15 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000001703 122.0
HFD2_k127_1838831_16 heat shock protein binding - - - 0.000000000000000005354 99.0
HFD2_k127_1838831_17 heat shock protein binding - - - 0.00000000000000007695 94.0
HFD2_k127_1838831_18 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000003522 86.0
HFD2_k127_1838831_19 Domain of unknown function (DUF4388) - - - 0.0000000000000007061 91.0
HFD2_k127_1838831_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 473.0
HFD2_k127_1838831_20 subunit of a heme lyase K02200 - - 0.000000008829 64.0
HFD2_k127_1838831_21 - - - - 0.000001509 59.0
HFD2_k127_1838831_22 Transposase K07491 - - 0.00006105 54.0
HFD2_k127_1838831_3 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 402.0
HFD2_k127_1838831_4 protein-disulfide reductase activity K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 381.0
HFD2_k127_1838831_5 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000004346 262.0
HFD2_k127_1838831_6 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007592 271.0
HFD2_k127_1838831_7 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000007106 248.0
HFD2_k127_1838831_8 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000006324 220.0
HFD2_k127_1838831_9 Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000001076 223.0
HFD2_k127_1962883_0 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 492.0
HFD2_k127_1962883_1 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 409.0
HFD2_k127_1962883_2 aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 384.0
HFD2_k127_1962883_3 ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 360.0
HFD2_k127_1962883_4 Glycogen recognition site of AMP-activated protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 316.0
HFD2_k127_1962883_5 Domain of Unknown Function (DUF349) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001105 305.0
HFD2_k127_1962883_6 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004853 273.0
HFD2_k127_1962883_7 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000468 209.0
HFD2_k127_1962883_8 Metallopeptidase family M24 K01265 - 3.4.11.18 0.0000000000000000000000000001251 117.0
HFD2_k127_2014674_0 peptidyl-tyrosine sulfation - - - 8.181e-261 825.0
HFD2_k127_2014674_1 Amidohydrolase family K06015 - 3.5.1.81 8.368e-231 730.0
HFD2_k127_2014674_10 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000007214 164.0
HFD2_k127_2014674_11 PFAM glycosyl transferase group 1 K00754 - - 0.0000000000000000000000000000000000008674 144.0
HFD2_k127_2014674_12 hydroperoxide reductase activity K01607 - 4.1.1.44 0.000000000000000000000000000001471 122.0
HFD2_k127_2014674_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 5.375e-207 660.0
HFD2_k127_2014674_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 527.0
HFD2_k127_2014674_4 PFAM GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 469.0
HFD2_k127_2014674_5 PFAM GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 406.0
HFD2_k127_2014674_6 Alcohol dehydrogenase GroES-like domain K00001,K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 385.0
HFD2_k127_2014674_7 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000000000000000000000003172 232.0
HFD2_k127_2014674_9 - - - - 0.00000000000000000000000000000000000000000133 157.0
HFD2_k127_2048313_0 GTP-binding protein TypA K06207 - - 1.302e-232 752.0
HFD2_k127_2048313_1 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 461.0
HFD2_k127_2048313_11 Periplasmic or secreted lipoprotein - - - 0.00000000000584 76.0
HFD2_k127_2048313_12 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000005027 75.0
HFD2_k127_2048313_13 Tetratricopeptide repeat - - - 0.0000000002302 72.0
HFD2_k127_2048313_14 methyltransferase - - - 0.0000007455 61.0
HFD2_k127_2048313_2 radical SAM domain protein K22318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 422.0
HFD2_k127_2048313_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 347.0
HFD2_k127_2048313_4 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004657 284.0
HFD2_k127_2048313_5 Lecithin:cholesterol acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000003861 235.0
HFD2_k127_2048313_6 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000001035 179.0
HFD2_k127_2048313_7 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000008018 129.0
HFD2_k127_2048313_8 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000002502 98.0
HFD2_k127_2048313_9 peptidyl-tyrosine sulfation K01277 - 3.4.14.4 0.0000000000002304 77.0
HFD2_k127_2111058_0 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 0.0 1050.0
HFD2_k127_2111058_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.149e-307 967.0
HFD2_k127_2111058_10 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 366.0
HFD2_k127_2111058_11 Succinylglutamate desuccinylase aspartoacylase K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 344.0
HFD2_k127_2111058_12 ABC transporter K01990,K19340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 350.0
HFD2_k127_2111058_13 ABC-2 family transporter protein K19341 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007274 282.0
HFD2_k127_2111058_14 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001812 276.0
HFD2_k127_2111058_15 Serine acetyltransferase, N-terminal K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000005491 271.0
HFD2_k127_2111058_16 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000247 235.0
HFD2_k127_2111058_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000327 240.0
HFD2_k127_2111058_18 lipoprotein involved in nitrous oxide reduction - - - 0.0000000000000000000000000000000000000000000000000000000000000001207 241.0
HFD2_k127_2111058_19 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000537 203.0
HFD2_k127_2111058_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 1.071e-226 709.0
HFD2_k127_2111058_20 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000004836 197.0
HFD2_k127_2111058_21 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000001337 194.0
HFD2_k127_2111058_22 - - - - 0.0000000000000000000000000000000000000000001108 163.0
HFD2_k127_2111058_23 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000003217 158.0
HFD2_k127_2111058_24 lipoprotein involved in nitrous oxide reduction K19342 - - 0.0000000000000000000000000000000002596 149.0
HFD2_k127_2111058_25 Kazal-type serine protease inhibitor domain - - - 0.000000000000000000005899 109.0
HFD2_k127_2111058_26 - - - - 0.0000001086 63.0
HFD2_k127_2111058_27 Methionine biosynthesis protein MetW - - - 0.00000634 57.0
HFD2_k127_2111058_3 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 612.0
HFD2_k127_2111058_4 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 586.0
HFD2_k127_2111058_5 oligopeptide transport K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 584.0
HFD2_k127_2111058_6 Periplasmic copper-binding protein (NosD) K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 562.0
HFD2_k127_2111058_7 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 542.0
HFD2_k127_2111058_8 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 471.0
HFD2_k127_2111058_9 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008584 387.0
HFD2_k127_2182787_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.84e-260 816.0
HFD2_k127_2182787_1 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 561.0
HFD2_k127_2182787_10 translation initiation inhibitor, yjgF family K04782 - 4.2.99.21 0.0000000000000000000000000000000000000000000000004092 181.0
HFD2_k127_2182787_11 - - - - 0.000000000000000000000000000000000000000000000000944 179.0
HFD2_k127_2182787_12 PFAM dehydrogenase, E1 component - - - 0.000000000000000000000000000000000000000000004113 185.0
HFD2_k127_2182787_13 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000003237 173.0
HFD2_k127_2182787_14 PFAM Hemolysin-type calcium-binding repeat (2 copies) K20276 - - 0.0000000000000000000000000000000000001053 164.0
HFD2_k127_2182787_15 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000001645 136.0
HFD2_k127_2182787_16 - - - - 0.00000000000000000000000000000005412 137.0
HFD2_k127_2182787_17 PFAM Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000114 98.0
HFD2_k127_2182787_18 YbbR-like protein - GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - 0.000000000001118 78.0
HFD2_k127_2182787_19 Endonuclease/Exonuclease/phosphatase family K07004 - - 0.0000003608 64.0
HFD2_k127_2182787_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 452.0
HFD2_k127_2182787_3 Putative methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 445.0
HFD2_k127_2182787_4 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 381.0
HFD2_k127_2182787_5 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 301.0
HFD2_k127_2182787_6 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 289.0
HFD2_k127_2182787_7 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000003218 269.0
HFD2_k127_2182787_8 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000002367 256.0
HFD2_k127_2182787_9 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000163 206.0
HFD2_k127_2189832_0 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 424.0
HFD2_k127_2189832_1 oligopeptide transport K03305 - - 0.000000000000000000000000000000000000000000000000000000000001113 226.0
HFD2_k127_2189832_2 - - - - 0.00000001373 64.0
HFD2_k127_2189832_3 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K01665 - 2.6.1.85,4.1.3.27 0.00000004478 67.0
HFD2_k127_2234353_0 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000803 275.0
HFD2_k127_2234353_1 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000129 275.0
HFD2_k127_2234353_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000339 220.0
HFD2_k127_2234353_3 Hfq protein - - - 0.000000000000000000000000000000001193 134.0
HFD2_k127_2234353_4 PpiC-type peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.0000000001876 72.0
HFD2_k127_2234353_5 Domain of unknown function DUF11 - - - 0.000000008188 64.0
HFD2_k127_2234353_6 peptidylprolyl isomerase K03770 - 5.2.1.8 0.000001045 61.0
HFD2_k127_2236279_0 cellulose binding - - - 0.0 1295.0
HFD2_k127_2236279_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000002557 248.0
HFD2_k127_2236279_2 - - - - 0.000000000000000000007435 100.0
HFD2_k127_2236279_3 FG-GAP repeat K20276 - - 0.000000002502 68.0
HFD2_k127_2264411_0 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 4.65e-300 943.0
HFD2_k127_2264411_1 belongs to the thioredoxin family K03671,K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 572.0
HFD2_k127_2264411_2 lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 319.0
HFD2_k127_2342964_0 involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 323.0
HFD2_k127_2342964_1 Thiamine biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 317.0
HFD2_k127_2342964_10 DNA helicase K03657 - 3.6.4.12 0.0000003287 65.0
HFD2_k127_2342964_2 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000002276 263.0
HFD2_k127_2342964_3 tRNA pseudouridine synthase activity K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000002382 220.0
HFD2_k127_2342964_4 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000212 231.0
HFD2_k127_2342964_5 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.000000000000000000000000000000000000001665 164.0
HFD2_k127_2342964_6 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000005867 150.0
HFD2_k127_2342964_7 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.00000000000000000000004144 114.0
HFD2_k127_2342964_8 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000001135 94.0
HFD2_k127_2342964_9 Sulfurtransferase TusA - - - 0.00000000000000002522 85.0
HFD2_k127_241487_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 3.914e-263 821.0
HFD2_k127_241487_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 427.0
HFD2_k127_241487_2 SMART PUA domain containing protein K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 388.0
HFD2_k127_241487_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 382.0
HFD2_k127_241487_4 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004372 276.0
HFD2_k127_241487_5 decarboxylase K13745 - 4.1.1.86 0.000000000000000000000000000000000000000000000000000000000000005919 245.0
HFD2_k127_241487_6 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000004313 199.0
HFD2_k127_241487_7 Belongs to the DEAD box helicase family - - - 0.0003759 47.0
HFD2_k127_2416647_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 638.0
HFD2_k127_2416647_1 IgA Peptidase M64 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000079 509.0
HFD2_k127_2416647_10 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000002054 121.0
HFD2_k127_2416647_11 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000008841 98.0
HFD2_k127_2416647_12 BolA-like protein - - - 0.0000000000004596 79.0
HFD2_k127_2416647_2 Bacterial regulatory protein, Fis family K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 403.0
HFD2_k127_2416647_3 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 385.0
HFD2_k127_2416647_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005969 295.0
HFD2_k127_2416647_5 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002166 286.0
HFD2_k127_2416647_6 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002866 252.0
HFD2_k127_2416647_7 MASE1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001065 265.0
HFD2_k127_2416647_8 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001691 238.0
HFD2_k127_2416647_9 PFAM peptidase M16 domain protein K07263 - - 0.000000000000000000000000000000000000000000000000000000000000007742 239.0
HFD2_k127_2436336_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1140.0
HFD2_k127_2436336_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 5.266e-227 719.0
HFD2_k127_2436336_10 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000001921 127.0
HFD2_k127_2436336_11 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000002147 133.0
HFD2_k127_2436336_12 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.000000000000000000003367 99.0
HFD2_k127_2436336_13 PFAM membrane-flanked domain - - - 0.000000000000000001352 92.0
HFD2_k127_2436336_14 PFAM Phosphate-selective porin O and P - - - 0.000000000000000007001 99.0
HFD2_k127_2436336_15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000004742 77.0
HFD2_k127_2436336_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.489e-223 714.0
HFD2_k127_2436336_3 PFAM peptidase M61 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 576.0
HFD2_k127_2436336_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007636 290.0
HFD2_k127_2436336_5 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000001653 227.0
HFD2_k127_2436336_6 Molybdate ABC transporter K02018 - - 0.000000000000000000000000000000000000000000000000000000000199 222.0
HFD2_k127_2436336_7 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000003876 212.0
HFD2_k127_2436336_8 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000002402 203.0
HFD2_k127_2436336_9 Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000005671 158.0
HFD2_k127_2483777_0 ABC transporter K06022,K06158,K10834 - 3.6.3.29,3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 480.0
HFD2_k127_2483777_1 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000833 382.0
HFD2_k127_2483777_2 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000000000014 122.0
HFD2_k127_2527017_0 OmpA family - - - 0.0 1935.0
HFD2_k127_2527017_1 Domain of unknown function DUF11 - - - 0.0 1339.0
HFD2_k127_2527017_2 transcription factor binding K02584 - - 1.047e-214 678.0
HFD2_k127_2527017_3 Tetratricopeptide repeat K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 497.0
HFD2_k127_2527017_4 molybdenum ion binding K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 300.0
HFD2_k127_2527017_5 Protein of unknown function (DUF1348) K09958 - - 0.00000000000000000000000000000000000000000000000000000000000006401 218.0
HFD2_k127_2527017_6 monooxygenase activity - - - 0.00000000000000000000000000000004893 134.0
HFD2_k127_2527017_7 Parallel beta-helix repeats - - - 0.00000000000000000007666 106.0
HFD2_k127_2527017_8 guanyl-nucleotide exchange factor activity - - - 0.00000000007378 76.0
HFD2_k127_2527017_9 amino acid activation for nonribosomal peptide biosynthetic process K05889 - 1.1.2.6 0.000000002654 71.0
HFD2_k127_2597895_0 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 605.0
HFD2_k127_2597895_1 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 534.0
HFD2_k127_2597895_10 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.00000000000000000000001093 113.0
HFD2_k127_2597895_11 Diguanylate cyclase - - - 0.000000000000003359 87.0
HFD2_k127_2597895_12 Tetratricopeptide repeat - - - 0.000000000000005606 90.0
HFD2_k127_2597895_13 Protein tyrosine kinase - - - 0.00000000000001252 89.0
HFD2_k127_2597895_2 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 482.0
HFD2_k127_2597895_3 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 379.0
HFD2_k127_2597895_4 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 389.0
HFD2_k127_2597895_5 SpoIVB peptidase S55 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 364.0
HFD2_k127_2597895_6 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001745 256.0
HFD2_k127_2597895_7 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000001598 251.0
HFD2_k127_2597895_8 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000002487 233.0
HFD2_k127_2597895_9 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000001512 210.0
HFD2_k127_2641462_0 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 576.0
HFD2_k127_2641462_1 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 519.0
HFD2_k127_2641462_2 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 308.0
HFD2_k127_2641462_3 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000000000003178 167.0
HFD2_k127_2641462_4 MULE transposase domain - - - 0.000000001237 65.0
HFD2_k127_2641462_5 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000002262 55.0
HFD2_k127_2650445_0 WD40-like Beta Propeller Repeat - - - 2.43e-236 759.0
HFD2_k127_2650445_1 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 525.0
HFD2_k127_2650445_10 Phosphodiester glycosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001269 269.0
HFD2_k127_2650445_11 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004474 258.0
HFD2_k127_2650445_12 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000003654 220.0
HFD2_k127_2650445_13 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000003344 200.0
HFD2_k127_2650445_14 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000004363 196.0
HFD2_k127_2650445_15 homoserine transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000001161 187.0
HFD2_k127_2650445_16 PFAM Neutral alkaline nonlysosomal ceramidase - - - 0.00000000000000000000000000000000000000000001579 187.0
HFD2_k127_2650445_17 COG0720 6-pyruvoyl-tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000003248 156.0
HFD2_k127_2650445_18 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.00000000000000000000000000000000000003918 157.0
HFD2_k127_2650445_19 PDZ DHR GLGF domain protein - - - 0.00000000000000000000000000000000002131 155.0
HFD2_k127_2650445_2 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 532.0
HFD2_k127_2650445_20 HEAT repeats - - - 0.0000000000000000000000000000000002378 146.0
HFD2_k127_2650445_21 alpha beta - - - 0.00000000000000000000001187 115.0
HFD2_k127_2650445_22 - - - - 0.0000000000000000000002456 112.0
HFD2_k127_2650445_23 - - - - 0.0000000000000000000023 102.0
HFD2_k127_2650445_24 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.00000000000000000000402 98.0
HFD2_k127_2650445_26 Metallo-peptidase family M12B Reprolysin-like - - - 0.00000000000000000006096 105.0
HFD2_k127_2650445_27 Amidohydrolase family - - - 0.00000000000000007806 96.0
HFD2_k127_2650445_28 von Willebrand factor (vWF) type A domain - - - 0.000000000000883 81.0
HFD2_k127_2650445_29 Glutathione S-transferase K00799 GO:0003674,GO:0003824,GO:0004364,GO:0005488,GO:0005515,GO:0005575,GO:0006950,GO:0008150,GO:0009635,GO:0009636,GO:0016740,GO:0016765,GO:0032991,GO:0042221,GO:0042802,GO:0042803,GO:0046983,GO:0050896 2.5.1.18 0.000000000518 68.0
HFD2_k127_2650445_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 460.0
HFD2_k127_2650445_30 PBS lyase HEAT-like repeat - - - 0.0000000051 69.0
HFD2_k127_2650445_31 - - - - 0.0001057 53.0
HFD2_k127_2650445_4 arylsulfatase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 419.0
HFD2_k127_2650445_5 Zinc metalloprotease (Elastase) K20274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 349.0
HFD2_k127_2650445_6 imidazolonepropionase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 308.0
HFD2_k127_2650445_7 A G-specific K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004393 301.0
HFD2_k127_2650445_8 S1/P1 Nuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005803 285.0
HFD2_k127_2650445_9 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001262 297.0
HFD2_k127_2689560_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 2.622e-219 699.0
HFD2_k127_2689560_1 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 2.019e-198 640.0
HFD2_k127_2689560_10 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 412.0
HFD2_k127_2689560_11 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 388.0
HFD2_k127_2689560_12 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 403.0
HFD2_k127_2689560_13 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 379.0
HFD2_k127_2689560_14 Endoribonuclease that initiates mRNA decay K05802,K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 375.0
HFD2_k127_2689560_15 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 370.0
HFD2_k127_2689560_16 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 363.0
HFD2_k127_2689560_17 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 348.0
HFD2_k127_2689560_18 transport system involved in gliding motility, auxiliary K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 349.0
HFD2_k127_2689560_19 ATPase activity K01990,K09697 - 3.6.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 332.0
HFD2_k127_2689560_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 2.391e-198 629.0
HFD2_k127_2689560_20 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 315.0
HFD2_k127_2689560_21 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 309.0
HFD2_k127_2689560_22 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 308.0
HFD2_k127_2689560_23 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 302.0
HFD2_k127_2689560_24 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 301.0
HFD2_k127_2689560_25 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 297.0
HFD2_k127_2689560_26 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000004173 287.0
HFD2_k127_2689560_27 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000001021 265.0
HFD2_k127_2689560_28 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001512 278.0
HFD2_k127_2689560_29 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001997 283.0
HFD2_k127_2689560_3 PFAM asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008753 557.0
HFD2_k127_2689560_30 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000004881 264.0
HFD2_k127_2689560_31 PFAM Peptidase family M20 M25 M40 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006313 261.0
HFD2_k127_2689560_32 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000003665 252.0
HFD2_k127_2689560_33 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000005448 265.0
HFD2_k127_2689560_34 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000001808 249.0
HFD2_k127_2689560_35 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000004911 228.0
HFD2_k127_2689560_36 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000001325 234.0
HFD2_k127_2689560_37 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000002701 215.0
HFD2_k127_2689560_38 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000006612 192.0
HFD2_k127_2689560_39 PFAM lipopolysaccharide biosynthesis protein K16554 - - 0.00000000000000000000000000000000000000000000000000009226 211.0
HFD2_k127_2689560_4 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 522.0
HFD2_k127_2689560_40 Glycosyl transferase 4-like - - - 0.00000000000000000000000000000000000000000000000003049 194.0
HFD2_k127_2689560_41 Sugar transferase - - - 0.0000000000000000000000000000000000000000000000001278 199.0
HFD2_k127_2689560_42 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000001444 196.0
HFD2_k127_2689560_43 SIS domain - - - 0.0000000000000000000000000000000000000000000000001943 194.0
HFD2_k127_2689560_44 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000001554 175.0
HFD2_k127_2689560_45 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000002489 184.0
HFD2_k127_2689560_46 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000001063 166.0
HFD2_k127_2689560_47 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000005285 177.0
HFD2_k127_2689560_48 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000000000000000000000000000000000000007308 166.0
HFD2_k127_2689560_49 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000002179 157.0
HFD2_k127_2689560_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00066 - 1.1.1.132 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 503.0
HFD2_k127_2689560_50 5'-nucleotidase - - - 0.0000000000000000000000000000000000000002247 166.0
HFD2_k127_2689560_51 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000003716 151.0
HFD2_k127_2689560_52 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000005479 163.0
HFD2_k127_2689560_53 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000114 143.0
HFD2_k127_2689560_54 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000002671 142.0
HFD2_k127_2689560_55 glycosyl transferase group 1 - - - 0.000000000000000000000000000000001655 143.0
HFD2_k127_2689560_56 TIGRFAM lipopolysaccharide heptosyltransferase II K02843 - - 0.000000000000000000000000000000009084 144.0
HFD2_k127_2689560_57 Yqey-like protein K09117 - - 0.00000000000000000000000000009002 121.0
HFD2_k127_2689560_58 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000001681 127.0
HFD2_k127_2689560_59 Peptidase M56 - - - 0.0000000000000000000000003579 121.0
HFD2_k127_2689560_6 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 474.0
HFD2_k127_2689560_60 Glycosyl transferases group 1 - - - 0.000000000000000000000001355 117.0
HFD2_k127_2689560_61 IMG reference gene - - - 0.000000000000000000000001655 119.0
HFD2_k127_2689560_62 - - - - 0.0000000000000000000007678 101.0
HFD2_k127_2689560_63 polysaccharide export K01991,K02237 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000001152 96.0
HFD2_k127_2689560_64 PFAM CBS domain containing protein - - - 0.00000000000000005374 87.0
HFD2_k127_2689560_65 Protein of unknown function (DUF3467) - - - 0.0000000000000008388 92.0
HFD2_k127_2689560_66 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000001429 89.0
HFD2_k127_2689560_67 - - - - 0.000000000000008309 80.0
HFD2_k127_2689560_68 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000002416 74.0
HFD2_k127_2689560_7 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 454.0
HFD2_k127_2689560_70 Domain of unknown function (DUF4340) - - - 0.00000000005646 75.0
HFD2_k127_2689560_72 Tetratricopeptide repeat - - - 0.0000002629 65.0
HFD2_k127_2689560_73 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000008227 55.0
HFD2_k127_2689560_74 COG3307 Lipid A core - O-antigen ligase and related enzymes K18814 - - 0.000001909 60.0
HFD2_k127_2689560_75 Curli production assembly/transport component CsgG - - - 0.000007938 59.0
HFD2_k127_2689560_8 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 463.0
HFD2_k127_2689560_9 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007818 423.0
HFD2_k127_272287_0 Belongs to the ompA family K03286 - - 0.00000000000002191 84.0
HFD2_k127_272287_1 PFAM Protein kinase - - - 0.000011 58.0
HFD2_k127_274288_0 transmembrane transporter activity K18138 - - 0.0 1605.0
HFD2_k127_274288_1 Alpha-glucan phosphorylase K00688 - 2.4.1.1 1.101e-309 972.0
HFD2_k127_274288_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 400.0
HFD2_k127_274288_11 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 399.0
HFD2_k127_274288_12 TLC ATP/ADP transporter K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000909 385.0
HFD2_k127_274288_13 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 392.0
HFD2_k127_274288_14 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 374.0
HFD2_k127_274288_15 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 372.0
HFD2_k127_274288_16 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007322 365.0
HFD2_k127_274288_17 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 332.0
HFD2_k127_274288_18 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 332.0
HFD2_k127_274288_19 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 319.0
HFD2_k127_274288_2 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 1.598e-253 815.0
HFD2_k127_274288_20 Pkd domain containing protein K12567 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000732 341.0
HFD2_k127_274288_21 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 310.0
HFD2_k127_274288_22 beta' subunit K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 306.0
HFD2_k127_274288_23 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000634 312.0
HFD2_k127_274288_24 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002232 282.0
HFD2_k127_274288_25 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001736 259.0
HFD2_k127_274288_26 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000001926 249.0
HFD2_k127_274288_27 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000003397 245.0
HFD2_k127_274288_28 Peptidase M36 - - - 0.0000000000000000000000000000000000000000000000000000000000000003054 252.0
HFD2_k127_274288_29 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems ATPase K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000001335 218.0
HFD2_k127_274288_3 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 597.0
HFD2_k127_274288_30 Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000393 228.0
HFD2_k127_274288_31 PFAM iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000000000000009331 215.0
HFD2_k127_274288_32 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000107 206.0
HFD2_k127_274288_33 - - - - 0.0000000000000000000000000000000000000000000000000001693 201.0
HFD2_k127_274288_34 palmitoyl-(protein) hydrolase activity K06999 - - 0.000000000000000000000000000000000000000000000000007911 198.0
HFD2_k127_274288_35 Endoribonuclease L-PSP K10013 - - 0.0000000000000000000000000000000000000000000000002421 180.0
HFD2_k127_274288_36 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000004203 185.0
HFD2_k127_274288_37 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000005519 178.0
HFD2_k127_274288_38 - - - - 0.0000000000000000000000000000000000000002859 162.0
HFD2_k127_274288_39 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000009552 138.0
HFD2_k127_274288_4 Pirin C-terminal cupin domain K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 530.0
HFD2_k127_274288_40 CYTH K05873 - 4.6.1.1 0.000000000000000000000000000000008492 135.0
HFD2_k127_274288_41 Tyrosine phosphatase family - - - 0.0000000000000000000000000000005582 142.0
HFD2_k127_274288_42 cellulose binding K12132 - 2.7.11.1 0.000000000000000000000000000008971 139.0
HFD2_k127_274288_43 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000334 120.0
HFD2_k127_274288_44 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000006964 117.0
HFD2_k127_274288_45 Thrombospondin type 3 repeat - - - 0.0000000000000000000000003177 124.0
HFD2_k127_274288_46 Protein of unknown function (DUF3999) - - - 0.0000000000000000000000003846 124.0
HFD2_k127_274288_47 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000003949 109.0
HFD2_k127_274288_48 transglycosylase associated protein - - - 0.00000000000000001726 86.0
HFD2_k127_274288_5 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 546.0
HFD2_k127_274288_51 pathogenesis - - - 0.000001005 59.0
HFD2_k127_274288_52 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000002369 61.0
HFD2_k127_274288_53 Bacterial Ig-like domain (group 3) - - - 0.000002566 62.0
HFD2_k127_274288_54 Uncharacterised nucleotidyltransferase - - - 0.000002621 59.0
HFD2_k127_274288_55 Belongs to the pirin family K06911 - - 0.000004207 49.0
HFD2_k127_274288_56 energy transducer activity K02283 - - 0.00001349 55.0
HFD2_k127_274288_57 YacP-like NYN domain K06962 - - 0.0002679 52.0
HFD2_k127_274288_58 Belongs to the pirin family K06911 - - 0.0004732 49.0
HFD2_k127_274288_6 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 519.0
HFD2_k127_274288_7 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 490.0
HFD2_k127_274288_8 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 454.0
HFD2_k127_274288_9 Belongs to the PstS family K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 404.0
HFD2_k127_2763693_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 597.0
HFD2_k127_2763693_1 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 555.0
HFD2_k127_2763693_2 imidazolonepropionase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 451.0
HFD2_k127_2763693_3 Sodium/calcium exchanger protein K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 406.0
HFD2_k127_2763693_4 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000004591 259.0
HFD2_k127_2763693_6 VIT family - - - 0.0000000000000000000000000000000000000002405 172.0
HFD2_k127_2763693_7 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000008896 148.0
HFD2_k127_2763693_8 Parallel beta-helix repeats - - - 0.00000000000000000002113 102.0
HFD2_k127_2787533_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 611.0
HFD2_k127_2787533_1 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 578.0
HFD2_k127_2787533_10 Peptidase family S51 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000162 285.0
HFD2_k127_2787533_11 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000000000000000000000000164 227.0
HFD2_k127_2787533_12 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.000000000000000000000000000000000000000000000000000000002361 211.0
HFD2_k127_2787533_13 PFAM MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000975 193.0
HFD2_k127_2787533_14 hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000004298 199.0
HFD2_k127_2787533_15 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.00000000000000000000000000000000000000003103 170.0
HFD2_k127_2787533_16 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000001876 156.0
HFD2_k127_2787533_17 Fic/DOC family K07341 - - 0.00000000000000000000121 98.0
HFD2_k127_2787533_18 transposition, DNA-mediated K02342 - 2.7.7.7 0.000000000002628 78.0
HFD2_k127_2787533_2 metallocarboxypeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 532.0
HFD2_k127_2787533_20 Fic/DOC family K07341 - - 0.0000002078 56.0
HFD2_k127_2787533_3 Proton-conducting membrane transporter K12141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 472.0
HFD2_k127_2787533_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 460.0
HFD2_k127_2787533_5 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006045 416.0
HFD2_k127_2787533_6 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 323.0
HFD2_k127_2787533_7 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 324.0
HFD2_k127_2787533_8 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 316.0
HFD2_k127_2787533_9 RNA pseudouridylate synthase K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 296.0
HFD2_k127_2811308_0 Dehydrogenase E1 component K11381 - 1.2.4.4 9.423e-275 864.0
HFD2_k127_2811308_1 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 445.0
HFD2_k127_2811308_10 pyridoxamine 5-phosphate - - - 0.0000161 53.0
HFD2_k127_2811308_2 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 335.0
HFD2_k127_2811308_3 Protein of unknown function (DUF2860) - - - 0.00000000000000000000000000000000000000000000000000000000000000002193 237.0
HFD2_k127_2811308_4 Cytochrome c - - - 0.00000000000000000000000000000000000000000000207 172.0
HFD2_k127_2811308_5 - - - - 0.000000000000000000000000000000008756 134.0
HFD2_k127_2811308_6 Integrin alpha (beta-propellor repeats). - - - 0.000000000000000000000000007401 117.0
HFD2_k127_2811308_7 Pfam:Pyridox_oxidase K01768 - 4.6.1.1 0.0000000000000000000000009989 118.0
HFD2_k127_2811308_8 COG0457 FOG TPR repeat - - - 0.00000000000000000000004275 114.0
HFD2_k127_2811308_9 - - - - 0.00000009674 63.0
HFD2_k127_2849156_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 553.0
HFD2_k127_2849156_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124 - - 0.00000000000000000000000001964 114.0
HFD2_k127_2849156_2 - - - - 0.0002405 44.0
HFD2_k127_2849233_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 2.139e-287 895.0
HFD2_k127_2849233_1 ABC-type multidrug transport system ATPase and permease K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006027 617.0
HFD2_k127_2849233_10 ethanolamine kinase activity K04343,K07251,K18844 - 2.7.1.72,2.7.1.89 0.0000000002174 72.0
HFD2_k127_2849233_11 Aminoglycoside phosphotransferase - - - 0.000001477 61.0
HFD2_k127_2849233_12 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.000002175 61.0
HFD2_k127_2849233_13 Domain of unknown function (DUF4215) - - - 0.0004893 51.0
HFD2_k127_2849233_14 Phosphotransferase enzyme family K11729 - - 0.0007905 52.0
HFD2_k127_2849233_2 ABC transporter K02003,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 462.0
HFD2_k127_2849233_3 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005479 369.0
HFD2_k127_2849233_4 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000001271 248.0
HFD2_k127_2849233_5 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000008368 233.0
HFD2_k127_2849233_6 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000002501 232.0
HFD2_k127_2849233_7 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000005216 202.0
HFD2_k127_2849233_8 polysaccharide catabolic process K03478 - 3.5.1.105 0.00000000000000000000000000000000000000396 165.0
HFD2_k127_2849233_9 - - - - 0.0000000000000000000000000000001227 130.0
HFD2_k127_290048_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.951e-199 649.0
HFD2_k127_290048_1 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 537.0
HFD2_k127_290048_2 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 349.0
HFD2_k127_290048_3 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000002061 243.0
HFD2_k127_290048_4 Hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000004117 234.0
HFD2_k127_290048_5 TonB dependent receptor K02014,K16089 - - 0.0000000000000000000000000000000000000000000000000009319 211.0
HFD2_k127_290048_6 chlorophyll binding - - - 0.00000000000000000000000000001319 134.0
HFD2_k127_290048_7 PFAM Protein-tyrosine phosphatase, low molecular weight K03741 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 0.00000000000000000000000000001771 124.0
HFD2_k127_2902295_0 Prolyl oligopeptidase family - - - 6.585e-226 740.0
HFD2_k127_2902295_1 nodulation K00612 - - 4.136e-209 692.0
HFD2_k127_2902295_2 Pterin 4 alpha carbinolamine dehydratase K01724,K11991 - 3.5.4.33,4.2.1.96 0.0000000000000000000000000000000000000000002372 170.0
HFD2_k127_2902295_3 PFAM Formaldehyde-activating enzyme (Fae) - - - 0.00000000000000000000000000000000000003892 150.0
HFD2_k127_2902295_4 PilZ domain - - - 0.0000003401 60.0
HFD2_k127_2902295_5 Domain of unknown function (DUF4149) - - - 0.0003251 52.0
HFD2_k127_2925667_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.046e-289 908.0
HFD2_k127_2925667_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 4.582e-263 842.0
HFD2_k127_2925667_10 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 368.0
HFD2_k127_2925667_11 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006742 361.0
HFD2_k127_2925667_12 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009246 359.0
HFD2_k127_2925667_13 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 354.0
HFD2_k127_2925667_14 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 342.0
HFD2_k127_2925667_15 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 330.0
HFD2_k127_2925667_16 Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) K00672 GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0030270,GO:0043446,GO:0044237,GO:0044281,GO:0071704 2.3.1.101 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 357.0
HFD2_k127_2925667_17 Type ii and iii secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 330.0
HFD2_k127_2925667_18 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 300.0
HFD2_k127_2925667_19 Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT K01499 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016787,GO:0016810,GO:0016814,GO:0018759,GO:0019238,GO:0043446,GO:0044237,GO:0044424,GO:0044464,GO:0071704 3.5.4.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 303.0
HFD2_k127_2925667_2 PFAM Type II secretion system protein E K02652 - - 9.403e-226 712.0
HFD2_k127_2925667_20 UreE urease accessory protein, C-terminal domain K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000005539 274.0
HFD2_k127_2925667_21 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000006608 270.0
HFD2_k127_2925667_22 Belongs to the RimK family K05827,K05844 - 6.3.2.43 0.00000000000000000000000000000000000000000000000000000000000000000000584 244.0
HFD2_k127_2925667_23 PFAM Formaldehyde-activating enzyme (Fae) K10713 - 4.2.1.147 0.00000000000000000000000000000000000000000000000000000000000000000006472 234.0
HFD2_k127_2925667_24 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000001124 239.0
HFD2_k127_2925667_25 Integrin alpha (beta-propellor repeats). - - - 0.000000000000000000000000000000000000000000000000000000000000000001527 259.0
HFD2_k127_2925667_26 transferase activity, transferring glycosyl groups K06984 - 2.4.2.54 0.0000000000000000000000000000000000000000000000000000000000000008763 239.0
HFD2_k127_2925667_27 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946,K07123 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.00000000000000000000000000000000000000000000000000001584 201.0
HFD2_k127_2925667_28 ATP:dephospho-CoA triphosphoribosyl transferase K05966 - 2.4.2.52 0.0000000000000000000000000000000000000000000000000006344 206.0
HFD2_k127_2925667_29 ATP cone domain K07738 - - 0.000000000000000000000000000000000000000000000000003332 199.0
HFD2_k127_2925667_3 Domain of unknown function (DUF362) - - - 2.318e-222 694.0
HFD2_k127_2925667_30 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000001631 203.0
HFD2_k127_2925667_31 ACT domain K12524 - 1.1.1.3,2.7.2.4 0.0000000000000000000000000000000000000000000000005491 198.0
HFD2_k127_2925667_32 glutamyl-tRNA reductase activity K02407,K02492,K10714,K15671 GO:0005575,GO:0005623,GO:0009288,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040 1.2.1.70 0.000000000000000000000000000000000000000000000009647 182.0
HFD2_k127_2925667_33 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000001021 181.0
HFD2_k127_2925667_34 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000002336 163.0
HFD2_k127_2925667_35 ATP-grasp domain K01499,K06913 - 3.5.4.27 0.00000000000000000000000000000000000000009496 168.0
HFD2_k127_2925667_36 - - - - 0.0000000000000000000000000000000000000001066 163.0
HFD2_k127_2925667_37 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000001777 166.0
HFD2_k127_2925667_38 Alkaline phosphatase family protein K01113 - 3.1.3.1 0.0000000000000000000000000000000000000002119 174.0
HFD2_k127_2925667_39 TLC ATP/ADP transporter K03301 - - 0.000000000000000000000000000000000003697 161.0
HFD2_k127_2925667_4 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 495.0
HFD2_k127_2925667_40 Protein of unknown function (DUF447) K09154 - - 0.000000000000000000000000000000000008776 149.0
HFD2_k127_2925667_41 general secretion pathway protein K02456 - - 0.000000000000000000000000001685 124.0
HFD2_k127_2925667_42 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000003311 115.0
HFD2_k127_2925667_43 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000875 118.0
HFD2_k127_2925667_44 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000009207 107.0
HFD2_k127_2925667_45 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000661 113.0
HFD2_k127_2925667_46 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000001921 103.0
HFD2_k127_2925667_47 Pilus assembly protein K02662 - - 0.00000000000000002809 94.0
HFD2_k127_2925667_48 PFAM CBS domain containing protein - - - 0.0000000000000001211 90.0
HFD2_k127_2925667_49 formylmethanofuran dehydrogenase, subunit K00201 - 1.2.7.12 0.000000000000002817 88.0
HFD2_k127_2925667_5 Formylmethanofuran dehydrogenase subunit A K00200 GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0044237,GO:0044281 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 464.0
HFD2_k127_2925667_50 TIGRFAM formylmethanofuran dehydrogenase subunit C K00202 - 1.2.7.12 0.00000000000002179 87.0
HFD2_k127_2925667_51 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000003667 86.0
HFD2_k127_2925667_52 general secretion pathway protein K02456,K02650 - - 0.000000000003267 78.0
HFD2_k127_2925667_53 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 GO:0003674,GO:0003824,GO:0004150,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0044424,GO:0044444,GO:0044464 1.13.11.81,4.1.2.25,5.1.99.8 0.000000006506 64.0
HFD2_k127_2925667_54 - K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000001147 61.0
HFD2_k127_2925667_55 PFAM Fimbrial assembly family protein K02663 - - 0.0000001275 65.0
HFD2_k127_2925667_56 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.0000001747 65.0
HFD2_k127_2925667_57 NmrA-like family - - - 0.00001622 51.0
HFD2_k127_2925667_58 4-HFC-P synthase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00001744 53.0
HFD2_k127_2925667_59 epimerase - - - 0.00006615 51.0
HFD2_k127_2925667_6 Creatinase/Prolidase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 439.0
HFD2_k127_2925667_60 - - - - 0.0008862 50.0
HFD2_k127_2925667_61 Cyclic nucleotide-monophosphate binding domain K07001 - - 0.0009931 50.0
HFD2_k127_2925667_7 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006136 430.0
HFD2_k127_2925667_8 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 421.0
HFD2_k127_2925667_9 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 446.0
HFD2_k127_2930861_0 Lipase maturation factor - - - 1.855e-206 658.0
HFD2_k127_2930861_1 Di-haem oxidoreductase, putative peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005784 255.0
HFD2_k127_2930861_10 endonuclease activity K07451 - - 0.000000000000000042 96.0
HFD2_k127_2930861_11 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000245 82.0
HFD2_k127_2930861_12 - - - - 0.00000000000001544 79.0
HFD2_k127_2930861_13 domain protein K20276 - - 0.00000000000003115 87.0
HFD2_k127_2930861_15 translation initiation factor activity K03699 - - 0.0000000000001701 79.0
HFD2_k127_2930861_17 mRNA binding - - - 0.0000924 48.0
HFD2_k127_2930861_2 endonuclease activity K07451 - - 0.0000000000000000000000000000000000000000000000000009017 209.0
HFD2_k127_2930861_3 spheroidene biosynthetic process K09844 GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016122,GO:0016123,GO:0016829,GO:0016835,GO:0016836,GO:0018904,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046148,GO:0071704,GO:1901178,GO:1901180,GO:1901503,GO:1901576 4.2.1.131 0.00000000000000000000000000000000000000000005778 169.0
HFD2_k127_2930861_4 Helix-turn-helix XRE-family like proteins K21498 - - 0.0000000000000000000000000000000000003245 143.0
HFD2_k127_2930861_5 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.00000000000000000000000000000000292 130.0
HFD2_k127_2930861_6 - - - - 0.0000000000000000000002637 103.0
HFD2_k127_2930861_9 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01179 - 3.2.1.4 0.000000000000000001468 101.0
HFD2_k127_299109_0 lysine biosynthetic process via aminoadipic acid - - - 7.258e-221 709.0
HFD2_k127_299109_1 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 474.0
HFD2_k127_299109_2 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004675 252.0
HFD2_k127_3070049_0 AAA-like domain K06915 - - 9.244e-242 766.0
HFD2_k127_3070049_1 C-terminus of AA_permease K03294 - - 7.586e-232 748.0
HFD2_k127_3070049_10 PFAM Aminotransferase, class I K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 400.0
HFD2_k127_3070049_11 isomerase activity K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 388.0
HFD2_k127_3070049_12 TIGRFAM Na H antiporter, bacterial form K03316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 310.0
HFD2_k127_3070049_13 NurA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001867 271.0
HFD2_k127_3070049_14 Pseudouridine synthase K06179,K06180 - 5.4.99.23,5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000272 250.0
HFD2_k127_3070049_15 2-hydroxychromene-2-carboxylate isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001836 243.0
HFD2_k127_3070049_16 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000000000000000826 223.0
HFD2_k127_3070049_17 PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain III, Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II, Phosphoglucomutase phosphomannomutase, C-terminal domain, Phosphoglucomutase phosphomannomutase, alpha beta alpha domain I K01835 - 5.4.2.2 0.000000000000000000000000000000000000000000000000000000003733 206.0
HFD2_k127_3070049_18 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000006315 213.0
HFD2_k127_3070049_19 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000003477 205.0
HFD2_k127_3070049_2 type ii restriction enzyme K01155 - 3.1.21.4 1.533e-195 618.0
HFD2_k127_3070049_20 Uncharacterized ACR, COG1993 K06199,K09137 - - 0.000000000000000000000000000000000000000000000000000009198 190.0
HFD2_k127_3070049_21 Histidine kinase K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000003089 199.0
HFD2_k127_3070049_22 tRNA wobble adenosine to inosine editing - - - 0.0000000000000000000000000000000000000000000000000957 194.0
HFD2_k127_3070049_23 regulation of DNA-templated transcription, elongation - - - 0.0000000000000000000000000000000000000000000006518 182.0
HFD2_k127_3070049_24 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000000000000002208 154.0
HFD2_k127_3070049_25 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 0.0000000000000000000000000000000000003739 145.0
HFD2_k127_3070049_26 Cupin superfamily (DUF985) K09705 - - 0.00000000000000000000000000000000000153 152.0
HFD2_k127_3070049_27 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000003076 139.0
HFD2_k127_3070049_28 AraC-like ligand binding domain - - - 0.000000000000000000000000000004533 126.0
HFD2_k127_3070049_29 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000002426 125.0
HFD2_k127_3070049_3 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 598.0
HFD2_k127_3070049_30 - - - - 0.0000000000000000003394 96.0
HFD2_k127_3070049_31 Domain of unknown function (DUF4136) - - - 0.0000000000000003168 86.0
HFD2_k127_3070049_32 - - - - 0.000000000000009309 85.0
HFD2_k127_3070049_33 - - - - 0.000000000009486 74.0
HFD2_k127_3070049_34 COG0457 FOG TPR repeat - - - 0.00000001341 66.0
HFD2_k127_3070049_35 - - - - 0.000004552 54.0
HFD2_k127_3070049_4 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 595.0
HFD2_k127_3070049_5 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 531.0
HFD2_k127_3070049_6 Domain of unknown function (DUF4338) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 451.0
HFD2_k127_3070049_7 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 435.0
HFD2_k127_3070049_8 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 424.0
HFD2_k127_3070049_9 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 389.0
HFD2_k127_3129971_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122,K00335 - 1.17.1.9,1.6.5.3 1.043e-223 710.0
HFD2_k127_3129971_1 2Fe-2S iron-sulfur cluster binding domain K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007786 455.0
HFD2_k127_3129971_2 Metallopeptidase family M24 K01265 - 3.4.11.18 0.0000000000000000000000000000000003122 137.0
HFD2_k127_3151490_0 Hydrolase CocE NonD family - - - 8.098e-306 951.0
HFD2_k127_3151490_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004464 264.0
HFD2_k127_3151490_2 Belongs to the peptidase S11 family K07258,K07262 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000001003 235.0
HFD2_k127_3151490_3 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000001594 239.0
HFD2_k127_3151490_4 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000001915 203.0
HFD2_k127_3176517_0 Malate synthase K01638 - 2.3.3.9 6.09e-225 712.0
HFD2_k127_3176517_1 Polysulphide reductase, NrfD K00185 - - 1.911e-222 698.0
HFD2_k127_3176517_10 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 338.0
HFD2_k127_3176517_11 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000002482 245.0
HFD2_k127_3176517_12 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000003551 244.0
HFD2_k127_3176517_13 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000000000000000007509 224.0
HFD2_k127_3176517_14 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000002602 229.0
HFD2_k127_3176517_15 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000003728 220.0
HFD2_k127_3176517_16 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000341 205.0
HFD2_k127_3176517_17 - - - - 0.000000000000000000000000000000000000000000000000000008425 194.0
HFD2_k127_3176517_18 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000007151 177.0
HFD2_k127_3176517_19 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000001001 195.0
HFD2_k127_3176517_2 Glycosyl hydrolases family 38 C-terminal domain K01191 - 3.2.1.24 1.542e-205 671.0
HFD2_k127_3176517_20 glyoxalase III activity - - - 0.000000000000000000000000000000000000000001234 163.0
HFD2_k127_3176517_21 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000003101 72.0
HFD2_k127_3176517_24 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00005725 48.0
HFD2_k127_3176517_3 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 3.316e-203 650.0
HFD2_k127_3176517_4 PFAM isocitrate lyase and phosphorylmutase K01637 - 4.1.3.1 9.507e-202 636.0
HFD2_k127_3176517_5 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 602.0
HFD2_k127_3176517_6 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 549.0
HFD2_k127_3176517_7 PFAM ABC transporter related K02049,K15555,K15578 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 487.0
HFD2_k127_3176517_8 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 472.0
HFD2_k127_3176517_9 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 433.0
HFD2_k127_3315413_0 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000000000000009071 158.0
HFD2_k127_3315413_1 Mut7-C RNAse domain K09122 - - 0.000000000000000000000009952 115.0
HFD2_k127_3315413_2 Carboxypeptidase regulatory-like domain - - - 0.0003787 53.0
HFD2_k127_3318471_0 COG3901 Regulator of nitric oxide reductase transcription K19339,K19343 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008556 412.0
HFD2_k127_3318471_1 Memo-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000163 259.0
HFD2_k127_3318471_2 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000002455 239.0
HFD2_k127_3352423_0 ABC-type multidrug transport system ATPase component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008996 355.0
HFD2_k127_3352423_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008433 306.0
HFD2_k127_3352423_2 HlyD family secretion protein K01993 - - 0.00000000000000000000000000000000000000000000003159 192.0
HFD2_k127_3352423_3 Redoxin K03386 - 1.11.1.15 0.00000000000005072 72.0
HFD2_k127_3352423_4 Regulatory protein tetr - - - 0.0003986 51.0
HFD2_k127_3353254_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 310.0
HFD2_k127_3353254_1 Sporulation related domain - - - 0.0000000000000000000000000000000005505 148.0
HFD2_k127_3353254_2 Sporulation related domain - - - 0.0000002739 64.0
HFD2_k127_3429184_0 PrkA AAA domain K07180 - - 6.573e-275 851.0
HFD2_k127_3429184_1 4Fe-4S single cluster domain K06937 - - 2.087e-240 772.0
HFD2_k127_3429184_10 glutamate--cysteine ligase K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 370.0
HFD2_k127_3429184_11 PFAM Formiminotransferase domain K00603 - 2.1.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009383 352.0
HFD2_k127_3429184_12 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000281 269.0
HFD2_k127_3429184_13 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000002117 245.0
HFD2_k127_3429184_14 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000002132 225.0
HFD2_k127_3429184_15 MotA TolQ ExbB proton channel K03561,K03562 - - 0.000000000000000000000000000000000000000000000000000000000000001019 226.0
HFD2_k127_3429184_16 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000001643 219.0
HFD2_k127_3429184_17 NUBPL iron-transfer P-loop NTPase K04562 - - 0.00000000000000000000000000000000000000001425 173.0
HFD2_k127_3429184_18 transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000000003641 118.0
HFD2_k127_3429184_19 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000306 104.0
HFD2_k127_3429184_2 SpoVR like protein K06415 - - 3.959e-207 660.0
HFD2_k127_3429184_20 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000000008184 103.0
HFD2_k127_3429184_21 TIGRFAM TonB K03832 - - 0.0000000000000000005105 97.0
HFD2_k127_3429184_22 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000001907 96.0
HFD2_k127_3429184_23 Fibronectin type 3 domain - - - 0.00000000000000002349 94.0
HFD2_k127_3429184_24 Tetratricopeptide repeat - - - 0.00000000000007962 82.0
HFD2_k127_3429184_25 Tetratricopeptide repeat - - - 0.00000000002418 74.0
HFD2_k127_3429184_26 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03087 - - 0.0000003245 57.0
HFD2_k127_3429184_27 Domain of unknown function (DUF4390) - - - 0.000002324 57.0
HFD2_k127_3429184_28 photosynthesis K00575,K02453,K20543 - 2.1.1.80 0.00000973 57.0
HFD2_k127_3429184_29 DNA primase - - - 0.00003364 46.0
HFD2_k127_3429184_3 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 619.0
HFD2_k127_3429184_30 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0001251 54.0
HFD2_k127_3429184_31 - K13486 - - 0.0005135 53.0
HFD2_k127_3429184_4 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 566.0
HFD2_k127_3429184_5 Belongs to the UPF0229 family K09786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 523.0
HFD2_k127_3429184_6 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 466.0
HFD2_k127_3429184_7 Belongs to the MurCDEF family K01921,K01924,K02558 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0042802,GO:0044424,GO:0044464 6.3.2.4,6.3.2.45,6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 468.0
HFD2_k127_3429184_8 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 471.0
HFD2_k127_3429184_9 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 381.0
HFD2_k127_3488874_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008008 389.0
HFD2_k127_3488874_1 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000009523 148.0
HFD2_k127_3488874_2 endonuclease III K01247 - 3.2.2.21 0.0000000005397 69.0
HFD2_k127_3554901_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 587.0
HFD2_k127_3554901_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 464.0
HFD2_k127_3554901_10 Bifunctional protein - - - 0.00000000000000000000000000000000000000000000000000000000005326 217.0
HFD2_k127_3554901_11 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000151 226.0
HFD2_k127_3554901_12 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002691 205.0
HFD2_k127_3554901_13 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000003901 200.0
HFD2_k127_3554901_14 HD domain - - - 0.0000000000000000000000000000000000000000000000000004581 197.0
HFD2_k127_3554901_15 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000001592 182.0
HFD2_k127_3554901_16 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000002812 184.0
HFD2_k127_3554901_17 Lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000008698 193.0
HFD2_k127_3554901_18 D,d-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000001914 193.0
HFD2_k127_3554901_19 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000002546 173.0
HFD2_k127_3554901_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 444.0
HFD2_k127_3554901_20 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000001595 165.0
HFD2_k127_3554901_21 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000002166 159.0
HFD2_k127_3554901_22 mitochondrial genome maintenance K02879,K16193 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000009729 155.0
HFD2_k127_3554901_23 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000001143 154.0
HFD2_k127_3554901_24 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000009318 158.0
HFD2_k127_3554901_25 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000031 143.0
HFD2_k127_3554901_26 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000001388 141.0
HFD2_k127_3554901_27 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000001474 126.0
HFD2_k127_3554901_28 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000001678 130.0
HFD2_k127_3554901_29 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000008798 131.0
HFD2_k127_3554901_3 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 324.0
HFD2_k127_3554901_30 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000006993 118.0
HFD2_k127_3554901_31 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000008393 90.0
HFD2_k127_3554901_32 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000006329 73.0
HFD2_k127_3554901_33 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000002151 71.0
HFD2_k127_3554901_34 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000002448 68.0
HFD2_k127_3554901_35 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000009005 66.0
HFD2_k127_3554901_4 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 322.0
HFD2_k127_3554901_5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003795 259.0
HFD2_k127_3554901_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004843 256.0
HFD2_k127_3554901_7 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000001286 255.0
HFD2_k127_3554901_8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000002185 236.0
HFD2_k127_3554901_9 Ribosomal protein S5, C-terminal domain K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000003174 215.0
HFD2_k127_3568189_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 611.0
HFD2_k127_3568189_1 ATP-dependent helicase K03579 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 591.0
HFD2_k127_3568189_10 Peptidase S9, prolyl oligopeptidase active site domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 356.0
HFD2_k127_3568189_11 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 345.0
HFD2_k127_3568189_12 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005363 301.0
HFD2_k127_3568189_13 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002022 284.0
HFD2_k127_3568189_14 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002593 271.0
HFD2_k127_3568189_15 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002586 263.0
HFD2_k127_3568189_16 Protein of unknown function (DUF1579) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004938 245.0
HFD2_k127_3568189_17 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000739 227.0
HFD2_k127_3568189_18 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000006066 221.0
HFD2_k127_3568189_19 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000001646 207.0
HFD2_k127_3568189_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 571.0
HFD2_k127_3568189_20 - - - - 0.0000000000000000000000000000000000000000000000005628 191.0
HFD2_k127_3568189_21 - K00003,K00058,K01754,K04517,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,1.3.1.12,4.3.1.19 0.0000000000000000000000000000000000000000000005886 173.0
HFD2_k127_3568189_22 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000003598 150.0
HFD2_k127_3568189_23 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000002077 142.0
HFD2_k127_3568189_24 Sortase family K07284 - 3.4.22.70 0.000000000000000000000000000000002341 139.0
HFD2_k127_3568189_25 - - - - 0.0000000000000000000000000009157 118.0
HFD2_k127_3568189_26 - - - - 0.000000000000000000000000505 112.0
HFD2_k127_3568189_27 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000000000000000000000005104 108.0
HFD2_k127_3568189_28 Domain of unknown function (DUF4136) - - - 0.00000000000000000000009268 115.0
HFD2_k127_3568189_29 - - - - 0.0000000000000000000002155 106.0
HFD2_k127_3568189_3 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005896 485.0
HFD2_k127_3568189_30 Putative 2OG-Fe(II) oxygenase - - - 0.0000000000000000000002985 110.0
HFD2_k127_3568189_31 D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.00000000000000000001579 95.0
HFD2_k127_3568189_32 OmpA-like transmembrane domain - - - 0.00000000000000004966 90.0
HFD2_k127_3568189_33 - - - - 0.000000000000002454 85.0
HFD2_k127_3568189_34 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000001747 74.0
HFD2_k127_3568189_35 domain, Protein - - - 0.0000000000001975 85.0
HFD2_k127_3568189_36 - - - - 0.0000000000002041 78.0
HFD2_k127_3568189_37 SMART Transport-associated and nodulation region K04065 - - 0.0000000006843 67.0
HFD2_k127_3568189_38 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000002119 61.0
HFD2_k127_3568189_39 Thrombospondin type 3 repeat - - - 0.0000002429 65.0
HFD2_k127_3568189_4 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 421.0
HFD2_k127_3568189_40 reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000001459 57.0
HFD2_k127_3568189_41 Putative zinc-finger - - - 0.000002197 54.0
HFD2_k127_3568189_42 protein trimerization K01206,K07114,K07126 - 3.2.1.51 0.0000797 55.0
HFD2_k127_3568189_5 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 433.0
HFD2_k127_3568189_6 Flotillin K07192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 386.0
HFD2_k127_3568189_7 PFAM Alanine dehydrogenase PNT, C-terminal domain K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 373.0
HFD2_k127_3568189_8 D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008493 362.0
HFD2_k127_3568189_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02022,K16922,K20345 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009353 372.0
HFD2_k127_3585733_0 MacB-like periplasmic core domain - - - 8.465e-317 992.0
HFD2_k127_3585733_1 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 346.0
HFD2_k127_3585733_10 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000001701 154.0
HFD2_k127_3585733_11 Mannosyltransferase (PIG-V) - - - 0.000000000000000000016 106.0
HFD2_k127_3585733_12 Putative Ig domain - - - 0.000000000000003183 91.0
HFD2_k127_3585733_13 - - - - 0.0000000000008302 81.0
HFD2_k127_3585733_14 Thiol disulfide interchange protein - - - 0.0000000002448 73.0
HFD2_k127_3585733_15 Thioredoxin-like - - - 0.00000006659 65.0
HFD2_k127_3585733_16 Cytochrome c - - - 0.0000001105 63.0
HFD2_k127_3585733_17 PA14 domain - GO:0005575,GO:0005576 - 0.000006772 52.0
HFD2_k127_3585733_18 metallopeptidase activity - - - 0.00001223 59.0
HFD2_k127_3585733_19 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00006735 46.0
HFD2_k127_3585733_2 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 343.0
HFD2_k127_3585733_20 Thiol disulfide interchange protein dsbA - - - 0.0001985 52.0
HFD2_k127_3585733_3 CHAP domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 333.0
HFD2_k127_3585733_4 Mo-co oxidoreductase dimerisation domain K00387 - 1.8.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 340.0
HFD2_k127_3585733_5 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 293.0
HFD2_k127_3585733_6 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007311 274.0
HFD2_k127_3585733_7 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001179 242.0
HFD2_k127_3585733_8 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000000000000000000000001684 185.0
HFD2_k127_3585733_9 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000001927 181.0
HFD2_k127_3664892_0 Glycosyl hydrolase family 63 C-terminal domain - - - 0.0 1367.0
HFD2_k127_3664892_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1140.0
HFD2_k127_3664892_10 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004101 279.0
HFD2_k127_3664892_11 uridine kinase K00876 - 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000002258 243.0
HFD2_k127_3664892_12 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000003414 214.0
HFD2_k127_3664892_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.000000000000000000000000000000000000000000000000003485 205.0
HFD2_k127_3664892_14 Cupin 2, conserved barrel domain protein K11477 - - 0.00000000000000000000000000000000000000000000004962 173.0
HFD2_k127_3664892_15 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000002305 163.0
HFD2_k127_3664892_16 Cupin 2, conserved barrel domain protein K11477 - - 0.0000000000000000000000000000000000001729 148.0
HFD2_k127_3664892_17 - - - - 0.000000000000000000000000000000000001363 153.0
HFD2_k127_3664892_18 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000004057 152.0
HFD2_k127_3664892_19 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000007418 153.0
HFD2_k127_3664892_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 1.009e-244 766.0
HFD2_k127_3664892_20 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000000000000000000001031 120.0
HFD2_k127_3664892_21 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000003672 100.0
HFD2_k127_3664892_22 Helix-turn-helix domain - - - 0.000000000000001677 90.0
HFD2_k127_3664892_23 TPR repeat - - - 0.000000000000009645 88.0
HFD2_k127_3664892_24 Putative zinc-finger - - - 0.0000000007808 64.0
HFD2_k127_3664892_25 Putative zinc-finger - - - 0.0000002464 62.0
HFD2_k127_3664892_26 - - - - 0.000001332 60.0
HFD2_k127_3664892_27 Putative zinc-finger - - - 0.000002712 59.0
HFD2_k127_3664892_3 Amylo-alpha-1,6-glucosidase - - - 4.24e-244 776.0
HFD2_k127_3664892_4 choline dehydrogenase activity - - - 4.738e-241 767.0
HFD2_k127_3664892_5 gluconolactonase activity K01053 - 3.1.1.17 7.865e-216 696.0
HFD2_k127_3664892_6 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 522.0
HFD2_k127_3664892_7 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 511.0
HFD2_k127_3664892_8 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 413.0
HFD2_k127_3664892_9 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 304.0
HFD2_k127_3668435_0 major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 470.0
HFD2_k127_3668435_1 amine oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008299 332.0
HFD2_k127_3668435_2 5-oxoprolinase (ATP-hydrolyzing) activity K07160 - - 0.000000000000000000000000000000000000000000000000000000000001235 218.0
HFD2_k127_3668435_3 ABC-2 family transporter protein K19341 - - 0.000000000000000000000000000000000000000000000000000000006396 203.0
HFD2_k127_3668435_4 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000000000000000000000000000000000006866 198.0
HFD2_k127_3668435_5 Allophanate hydrolase subunit 2 K06350 - - 0.000000000000000000000000000000000000001898 154.0
HFD2_k127_3668435_6 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000001079 126.0
HFD2_k127_3668435_7 Helix-turn-helix domain - - - 0.00000000000000000682 87.0
HFD2_k127_3668880_0 DNA Topoisomerase IV K02469 - 5.99.1.3 0.0 1017.0
HFD2_k127_3668880_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.279e-297 936.0
HFD2_k127_3668880_2 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 1.649e-242 761.0
HFD2_k127_3668880_3 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 514.0
HFD2_k127_3668880_4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 460.0
HFD2_k127_3668880_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 303.0
HFD2_k127_3760582_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 458.0
HFD2_k127_3760582_1 Belongs to the phosphoglycerate kinase family K00927 GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008852 432.0
HFD2_k127_3760582_10 Evidence 5 No homology to any previously reported sequences K09005 - - 0.000000000000000000000000003506 120.0
HFD2_k127_3760582_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000008014 113.0
HFD2_k127_3760582_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000002435 127.0
HFD2_k127_3760582_13 PFAM Lytic K08309 - - 0.00000000000000000004859 103.0
HFD2_k127_3760582_14 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 0.0000001593 55.0
HFD2_k127_3760582_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 346.0
HFD2_k127_3760582_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 309.0
HFD2_k127_3760582_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000001043 245.0
HFD2_k127_3760582_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000007934 234.0
HFD2_k127_3760582_6 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000002672 173.0
HFD2_k127_3760582_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000004122 164.0
HFD2_k127_3760582_8 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.000000000000000000000000000000003617 132.0
HFD2_k127_3760582_9 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000005257 129.0
HFD2_k127_3764287_0 Sulfite reductase K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 4.691e-294 920.0
HFD2_k127_3764287_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 4.304e-265 847.0
HFD2_k127_3764287_10 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 416.0
HFD2_k127_3764287_11 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 421.0
HFD2_k127_3764287_12 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 382.0
HFD2_k127_3764287_13 PFAM amidohydrolase K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 376.0
HFD2_k127_3764287_14 PNKP adenylyltransferase domain, C-terminal region K01090 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 362.0
HFD2_k127_3764287_15 PFAM peptidase S1 and S6 chymotrypsin Hap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 366.0
HFD2_k127_3764287_16 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004944 347.0
HFD2_k127_3764287_17 Mechanosensitive ion channel K05802 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 332.0
HFD2_k127_3764287_18 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 317.0
HFD2_k127_3764287_19 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001581 296.0
HFD2_k127_3764287_2 PFAM Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 1.113e-214 681.0
HFD2_k127_3764287_20 copper resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002239 262.0
HFD2_k127_3764287_21 COG3119 Arylsulfatase A and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001391 262.0
HFD2_k127_3764287_22 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000002047 254.0
HFD2_k127_3764287_23 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000004364 266.0
HFD2_k127_3764287_24 PFAM FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000004723 231.0
HFD2_k127_3764287_25 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000002712 213.0
HFD2_k127_3764287_26 chitinase - - - 0.00000000000000000000000000000000000000000000000000000000009531 235.0
HFD2_k127_3764287_27 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000009852 204.0
HFD2_k127_3764287_28 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000007178 217.0
HFD2_k127_3764287_29 Belongs to the precorrin methyltransferase family K02303 - 2.1.1.107 0.000000000000000000000000000000000000000000000000000004835 211.0
HFD2_k127_3764287_3 Protein of unknown function, DUF255 K06888 - - 1.996e-200 646.0
HFD2_k127_3764287_30 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000001736 201.0
HFD2_k127_3764287_31 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000000000000002649 199.0
HFD2_k127_3764287_32 photosynthesis - - - 0.000000000000000000000000000000000000000000000012 177.0
HFD2_k127_3764287_33 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000003472 191.0
HFD2_k127_3764287_34 B12 binding domain - - - 0.000000000000000000000000000000000000000000001466 188.0
HFD2_k127_3764287_35 Zn peptidase - - - 0.0000000000000000000000000000000000000000002838 179.0
HFD2_k127_3764287_36 PFAM Formiminotransferase-cyclodeaminase - - - 0.0000000000000000000000000000000000000002263 157.0
HFD2_k127_3764287_37 6-phosphogluconolactonase activity - - - 0.00000000000000000000000000000001034 151.0
HFD2_k127_3764287_38 Reverse transcriptase-like K03469 - 3.1.26.4 0.0000000000000000000000000000002412 131.0
HFD2_k127_3764287_39 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.00000000000000000000000001415 120.0
HFD2_k127_3764287_4 efflux transmembrane transporter activity K02004 - - 1.845e-199 648.0
HFD2_k127_3764287_40 Thrombospondin type 3 - - - 0.00000000000000000000000003732 129.0
HFD2_k127_3764287_41 PFAM DivIVA family protein K04074 - - 0.0000000000000000000000339 113.0
HFD2_k127_3764287_42 guanyl-nucleotide exchange factor activity - - - 0.000000000000000000003475 111.0
HFD2_k127_3764287_43 Subtilase family - - - 0.000000000000000000008405 111.0
HFD2_k127_3764287_45 - - - - 0.000000000000000004227 95.0
HFD2_k127_3764287_46 cellulase activity K01183 - 3.2.1.14 0.000000000000000007787 100.0
HFD2_k127_3764287_47 Subtilase family - - - 0.00000000000000001065 101.0
HFD2_k127_3764287_48 C4-type zinc ribbon domain K07164 - - 0.00000000000000001632 94.0
HFD2_k127_3764287_49 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01179 - 3.2.1.4 0.0000000000000002831 95.0
HFD2_k127_3764287_5 Dehydrogenase E1 component K11381 - 1.2.4.4 5.672e-195 629.0
HFD2_k127_3764287_50 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.0000000000000006435 80.0
HFD2_k127_3764287_51 endonuclease activity K07451 - - 0.000000000000003833 90.0
HFD2_k127_3764287_52 oxidoreductase activity - - - 0.00000000000002229 87.0
HFD2_k127_3764287_53 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000002304 87.0
HFD2_k127_3764287_54 Cold shock K03704 - - 0.0000000000002651 72.0
HFD2_k127_3764287_55 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000008471 76.0
HFD2_k127_3764287_56 Periplasmic copper-binding protein (NosD) - - - 0.0000000004159 72.0
HFD2_k127_3764287_57 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000008015 73.0
HFD2_k127_3764287_59 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000001652 60.0
HFD2_k127_3764287_6 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 546.0
HFD2_k127_3764287_60 Tetratricopeptide repeat - - - 0.000003299 61.0
HFD2_k127_3764287_61 COG3209 Rhs family protein - - - 0.000004417 56.0
HFD2_k127_3764287_62 calcium- and calmodulin-responsive adenylate cyclase activity K01179 - 3.2.1.4 0.000006896 61.0
HFD2_k127_3764287_63 Tetratricopeptide repeat - - - 0.000006925 59.0
HFD2_k127_3764287_64 Involved in the TonB-independent uptake of proteins K03641 - - 0.00001035 58.0
HFD2_k127_3764287_65 oxidoreductase activity K07114 - - 0.0006501 53.0
HFD2_k127_3764287_7 Aminotransferase, class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006436 503.0
HFD2_k127_3764287_8 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 455.0
HFD2_k127_3764287_9 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 466.0
HFD2_k127_3817630_0 Berberine and berberine like - - - 8.798e-223 703.0
HFD2_k127_3817630_1 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 457.0
HFD2_k127_3817630_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 379.0
HFD2_k127_3817630_3 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 366.0
HFD2_k127_3817630_4 Adenylate cyclase - - - 0.000000005044 58.0
HFD2_k127_3817630_6 CAAX protease self-immunity - - - 0.00001286 55.0
HFD2_k127_3845281_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006438 584.0
HFD2_k127_3845281_1 Protein of unknown function (DUF1326) - - - 0.000005742 55.0
HFD2_k127_3860527_0 SPFH domain / Band 7 family - - - 7.714e-252 788.0
HFD2_k127_3864413_0 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000001144 229.0
HFD2_k127_3864413_1 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000009157 218.0
HFD2_k127_3864413_2 membrane K07148 - - 0.000000000000000000000000000000000000000002116 173.0
HFD2_k127_3916937_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 439.0
HFD2_k127_3916937_1 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000001453 172.0
HFD2_k127_3916937_2 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000001853 136.0
HFD2_k127_3917231_0 PFAM extracellular solute-binding protein family 1 K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 330.0
HFD2_k127_3917231_1 COG1176 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 320.0
HFD2_k127_3917231_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052,K11072 - 3.6.3.31 0.0000000000000006994 80.0
HFD2_k127_4003056_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1492.0
HFD2_k127_4003056_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 1.676e-239 769.0
HFD2_k127_4003056_10 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 385.0
HFD2_k127_4003056_11 N-4 methylation of cytosine K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 363.0
HFD2_k127_4003056_12 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 358.0
HFD2_k127_4003056_13 Domain of unknown function (DUF1858) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 353.0
HFD2_k127_4003056_14 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 321.0
HFD2_k127_4003056_15 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003093 279.0
HFD2_k127_4003056_16 ABC transporter K01990,K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000007647 249.0
HFD2_k127_4003056_17 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000008291 221.0
HFD2_k127_4003056_18 Enoyl-(Acyl carrier protein) reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.00000000000000000000000000000000000000000000000000000002535 218.0
HFD2_k127_4003056_19 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000000000000001006 205.0
HFD2_k127_4003056_2 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 4.787e-217 694.0
HFD2_k127_4003056_20 - - - - 0.0000000000000000000000000000000000000000000000000000001182 210.0
HFD2_k127_4003056_21 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.000000000000000000000000000000000000000000000000000002911 195.0
HFD2_k127_4003056_22 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000003248 196.0
HFD2_k127_4003056_23 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000007259 175.0
HFD2_k127_4003056_24 Histidine kinase K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000002811 181.0
HFD2_k127_4003056_25 Lamin Tail Domain - - - 0.0000000000000000000000000000000000000002581 173.0
HFD2_k127_4003056_26 HEPN domain - - - 0.000000000000000000000000000000000000297 145.0
HFD2_k127_4003056_27 PFAM Uncharacterised BCR, COG1649 - - - 0.000000000000000000000000000000000006293 161.0
HFD2_k127_4003056_28 Radical SAM - - - 0.00000000000000000000000000000000001786 141.0
HFD2_k127_4003056_29 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.000000000000000000000000000000006037 143.0
HFD2_k127_4003056_3 Beta-eliminating lyase K01667 - 4.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007315 584.0
HFD2_k127_4003056_30 ABC-2 family transporter protein K09696 - - 0.00000000000000000000000000000000891 145.0
HFD2_k127_4003056_31 COG2931 RTX toxins and related Ca2 -binding proteins K01406,K07004 - 3.4.24.40 0.0000000000000000000000000000002814 143.0
HFD2_k127_4003056_32 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000001646 121.0
HFD2_k127_4003056_33 AMP binding - - - 0.000000000000000000000000007401 117.0
HFD2_k127_4003056_34 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000001359 108.0
HFD2_k127_4003056_35 Uncharacterised protein - - - 0.0000000000000002212 96.0
HFD2_k127_4003056_37 Tetratricopeptide repeat - - - 0.000000003588 70.0
HFD2_k127_4003056_38 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.00000001617 70.0
HFD2_k127_4003056_4 response regulator K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 479.0
HFD2_k127_4003056_40 Nucleotidyltransferase domain - - - 0.0000001665 58.0
HFD2_k127_4003056_41 Putative regulatory protein - - - 0.000001627 52.0
HFD2_k127_4003056_42 negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment - - - 0.000003904 62.0
HFD2_k127_4003056_5 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 449.0
HFD2_k127_4003056_6 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004996 434.0
HFD2_k127_4003056_7 S-(hydroxymethyl)glutathione dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 437.0
HFD2_k127_4003056_8 Dihydroorotate dehydrogenase K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 402.0
HFD2_k127_4003056_9 benzoyl-CoA reductase K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007042 418.0
HFD2_k127_4054200_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.925e-232 751.0
HFD2_k127_4054200_1 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 585.0
HFD2_k127_4054200_10 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000001137 229.0
HFD2_k127_4054200_11 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.000000000000000000000000000000000000000000000000001837 191.0
HFD2_k127_4054200_12 TPR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000006975 192.0
HFD2_k127_4054200_13 CotH kinase protein - - - 0.0000000000000000000000000000441 136.0
HFD2_k127_4054200_14 PA14 domain - GO:0005575,GO:0005576 - 0.000000183 65.0
HFD2_k127_4054200_15 - - - - 0.0002775 53.0
HFD2_k127_4054200_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009363 504.0
HFD2_k127_4054200_3 PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 407.0
HFD2_k127_4054200_4 Major intrinsic protein K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 352.0
HFD2_k127_4054200_5 PFAM Integrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000034 297.0
HFD2_k127_4054200_6 chitinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002524 302.0
HFD2_k127_4054200_7 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001027 269.0
HFD2_k127_4054200_8 COG1078 HD superfamily phosphohydrolases K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000006527 278.0
HFD2_k127_4054200_9 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000024 246.0
HFD2_k127_4098476_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1036.0
HFD2_k127_4098476_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 429.0
HFD2_k127_4098476_10 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000003773 221.0
HFD2_k127_4098476_11 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000001527 213.0
HFD2_k127_4098476_12 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000002394 205.0
HFD2_k127_4098476_13 Telomere recombination K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000002591 190.0
HFD2_k127_4098476_14 Rossmann-like domain - - - 0.00000000000000000000000000000000000000001206 174.0
HFD2_k127_4098476_15 RNA 2'-O ribose methyltransferase substrate binding K03437 - - 0.00000000000000000000000000000000000000008722 164.0
HFD2_k127_4098476_16 - - - - 0.0000000000000000000000000000000000000002109 161.0
HFD2_k127_4098476_17 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000001844 166.0
HFD2_k127_4098476_18 Peptidase family M23 K21471 - - 0.0000000000000000000000000000000000002997 158.0
HFD2_k127_4098476_19 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000002224 144.0
HFD2_k127_4098476_2 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 394.0
HFD2_k127_4098476_20 PFAM response regulator receiver K07657 - - 0.0000000000000000000000000005669 117.0
HFD2_k127_4098476_21 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000001557 122.0
HFD2_k127_4098476_22 guanyl-nucleotide exchange factor activity - - - 0.00000000000000000000000001007 126.0
HFD2_k127_4098476_23 zinc ion binding K06204 - - 0.0000000000000000003568 92.0
HFD2_k127_4098476_24 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000003135 94.0
HFD2_k127_4098476_25 histone H2A K63-linked ubiquitination - - - 0.0000000000000225 87.0
HFD2_k127_4098476_26 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000003732 66.0
HFD2_k127_4098476_27 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000006143 66.0
HFD2_k127_4098476_28 Belongs to the 'phage' integrase family - - - 0.000000001218 67.0
HFD2_k127_4098476_29 Outer membrane protein, OMP85 family K07277 - - 0.00000006608 65.0
HFD2_k127_4098476_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 395.0
HFD2_k127_4098476_30 Belongs to the ompA family K03286 - - 0.0000001389 61.0
HFD2_k127_4098476_31 Transcriptional regulatory protein, C terminal K02483 - - 0.00004305 55.0
HFD2_k127_4098476_4 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 339.0
HFD2_k127_4098476_5 PFAM aminotransferase class V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 318.0
HFD2_k127_4098476_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004327 286.0
HFD2_k127_4098476_7 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000143 263.0
HFD2_k127_4098476_8 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000002991 235.0
HFD2_k127_4098476_9 TIGRFAM Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000003244 232.0
HFD2_k127_415571_0 cyclic 2,3-diphosphoglycerate synthetase activity K05716 - - 1.903e-194 617.0
HFD2_k127_415571_1 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 571.0
HFD2_k127_415571_10 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 330.0
HFD2_k127_415571_11 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 325.0
HFD2_k127_415571_12 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 304.0
HFD2_k127_415571_13 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000491 294.0
HFD2_k127_415571_14 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004877 284.0
HFD2_k127_415571_15 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004996 255.0
HFD2_k127_415571_16 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000001816 211.0
HFD2_k127_415571_17 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000008865 212.0
HFD2_k127_415571_18 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000001783 196.0
HFD2_k127_415571_19 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000006179 199.0
HFD2_k127_415571_2 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 495.0
HFD2_k127_415571_20 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000002992 205.0
HFD2_k127_415571_21 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000004019 191.0
HFD2_k127_415571_22 polysaccharide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000001215 207.0
HFD2_k127_415571_23 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000005511 196.0
HFD2_k127_415571_24 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000001434 198.0
HFD2_k127_415571_25 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000002493 182.0
HFD2_k127_415571_26 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000004722 179.0
HFD2_k127_415571_27 - - - - 0.00000000000000000000000000000000000000000004647 173.0
HFD2_k127_415571_28 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000002921 163.0
HFD2_k127_415571_29 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07710 - 2.7.13.3 0.000000000000000000000000000000000000000009379 179.0
HFD2_k127_415571_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 422.0
HFD2_k127_415571_30 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000001559 79.0
HFD2_k127_415571_31 - - - - 0.00000000569 68.0
HFD2_k127_415571_32 Fibronectin type 3 domain - - - 0.00000003386 68.0
HFD2_k127_415571_33 O-Antigen ligase K18814 - - 0.00000004866 66.0
HFD2_k127_415571_34 Tfp pilus assembly protein FimT K08084,K08085 - - 0.00001112 54.0
HFD2_k127_415571_4 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 419.0
HFD2_k127_415571_5 Heparinase II/III-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009627 396.0
HFD2_k127_415571_6 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 367.0
HFD2_k127_415571_7 Flavin containing amine oxidoreductase K00231,K01854 - 1.3.3.15,1.3.3.4,5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 387.0
HFD2_k127_415571_8 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 351.0
HFD2_k127_415571_9 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 316.0
HFD2_k127_4172417_0 Tricorn protease homolog K08676 - - 8.05e-302 963.0
HFD2_k127_4172417_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.402e-284 895.0
HFD2_k127_4172417_10 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002 254.0
HFD2_k127_4172417_11 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000001283 232.0
HFD2_k127_4172417_12 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000003707 225.0
HFD2_k127_4172417_13 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000009195 219.0
HFD2_k127_4172417_14 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000115 230.0
HFD2_k127_4172417_15 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000008134 205.0
HFD2_k127_4172417_16 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000001946 168.0
HFD2_k127_4172417_17 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000002283 147.0
HFD2_k127_4172417_18 Binds the 23S rRNA K02909 - - 0.000000000000000000000000006536 115.0
HFD2_k127_4172417_19 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.00000000000000000005756 104.0
HFD2_k127_4172417_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 6.84e-216 691.0
HFD2_k127_4172417_20 Beta-xylanase K01181 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010383,GO:0010410,GO:0016052,GO:0016787,GO:0016798,GO:0030312,GO:0031176,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0045491,GO:0045493,GO:0071554,GO:0071704,GO:0071944,GO:0097599,GO:1901575 3.2.1.8 0.000000000000000007607 99.0
HFD2_k127_4172417_21 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate - - - 0.000000000000004932 81.0
HFD2_k127_4172417_23 chitinase K01183 - 3.2.1.14 0.000001344 62.0
HFD2_k127_4172417_24 Nacht domain - - - 0.00005955 57.0
HFD2_k127_4172417_25 Glycosyl transferase family 41 - - - 0.0001567 53.0
HFD2_k127_4172417_26 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0002375 53.0
HFD2_k127_4172417_27 Iron-sulfur cluster-binding domain - - - 0.0003852 54.0
HFD2_k127_4172417_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 546.0
HFD2_k127_4172417_4 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 533.0
HFD2_k127_4172417_5 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 525.0
HFD2_k127_4172417_6 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 440.0
HFD2_k127_4172417_7 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 421.0
HFD2_k127_4172417_8 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 292.0
HFD2_k127_4172417_9 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000005829 256.0
HFD2_k127_4184062_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 552.0
HFD2_k127_4184062_1 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 435.0
HFD2_k127_4184062_10 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001676 284.0
HFD2_k127_4184062_11 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001892 269.0
HFD2_k127_4184062_12 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005828 287.0
HFD2_k127_4184062_13 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000006099 265.0
HFD2_k127_4184062_14 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000428 256.0
HFD2_k127_4184062_15 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005794 249.0
HFD2_k127_4184062_16 Domain of unknown function (DUF1730) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000004838 255.0
HFD2_k127_4184062_17 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000002065 223.0
HFD2_k127_4184062_18 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000004631 203.0
HFD2_k127_4184062_19 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000001917 205.0
HFD2_k127_4184062_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 404.0
HFD2_k127_4184062_20 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000002421 140.0
HFD2_k127_4184062_21 PFAM Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000001305 144.0
HFD2_k127_4184062_22 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000007283 113.0
HFD2_k127_4184062_23 Uncharacterized ACR, COG1399 K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000002103 112.0
HFD2_k127_4184062_24 Haloacid dehalogenase domain protein hydrolase K07025 - - 0.00000000000000000000001401 111.0
HFD2_k127_4184062_25 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000001481 94.0
HFD2_k127_4184062_26 Regulatory protein - - - 0.00000000000000000005496 96.0
HFD2_k127_4184062_27 Acylphosphatase K01512 - 3.6.1.7 0.00000000000004882 86.0
HFD2_k127_4184062_28 heat shock protein binding - - - 0.00000000003128 76.0
HFD2_k127_4184062_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 402.0
HFD2_k127_4184062_30 chaperone-mediated protein folding - - - 0.0007381 52.0
HFD2_k127_4184062_4 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 387.0
HFD2_k127_4184062_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621,K21576,K21577 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.21.4.2,1.21.4.3,1.21.4.4,2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 365.0
HFD2_k127_4184062_6 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 317.0
HFD2_k127_4184062_7 Zinc-binding dehydrogenase K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 309.0
HFD2_k127_4184062_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005681 319.0
HFD2_k127_4184062_9 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 294.0
HFD2_k127_4275103_0 Peptidase family M23 K01406 - 3.4.24.40 0.00000000000000000000000000000000000000000000006821 182.0
HFD2_k127_4275103_1 cyclic nucleotide-binding K10914 - - 0.000000000000000000004548 102.0
HFD2_k127_4311955_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 2.307e-317 1000.0
HFD2_k127_4311955_1 glutamate dehydrogenase [NAD(P)+] activity K00262 - 1.4.1.4 2.507e-254 790.0
HFD2_k127_4311955_2 Lysylphosphatidylglycerol synthase TM region K07027,K14205 - 2.3.2.3 2.552e-252 811.0
HFD2_k127_4311955_3 PQQ-like domain K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 432.0
HFD2_k127_4311955_4 DEAD DEAH box helicase domain protein K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 416.0
HFD2_k127_4311955_5 Bacterial virulence protein (VirJ) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007718 296.0
HFD2_k127_4311955_6 - - - - 0.000000000000000000000000000000000000000000000000001105 190.0
HFD2_k127_4311955_7 endonuclease activity K07451 - - 0.000000000000000000000000000000000000000000000000007956 204.0
HFD2_k127_4311955_8 ABC transporter K01989 - - 0.00000000000000293 89.0
HFD2_k127_4311955_9 - - - - 0.000001013 56.0
HFD2_k127_4320140_0 iron-nicotianamine transmembrane transporter activity - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008017 582.0
HFD2_k127_4320140_1 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 539.0
HFD2_k127_4320140_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 383.0
HFD2_k127_4320140_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 357.0
HFD2_k127_4320140_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 305.0
HFD2_k127_4320140_5 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002495 274.0
HFD2_k127_4320140_6 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000003418 197.0
HFD2_k127_4328700_0 PrkA AAA domain K07180 - - 0.0 1090.0
HFD2_k127_4328700_1 Belongs to the ClpA ClpB family K03696 - - 3.087e-289 910.0
HFD2_k127_4328700_10 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000006989 233.0
HFD2_k127_4328700_11 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000004306 223.0
HFD2_k127_4328700_12 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000003981 224.0
HFD2_k127_4328700_13 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000001744 201.0
HFD2_k127_4328700_14 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372,K16363 - 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000000000000002417 193.0
HFD2_k127_4328700_15 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000008128 191.0
HFD2_k127_4328700_16 ggdef domain - - - 0.000000000000000000000000000000000000000000000000001225 202.0
HFD2_k127_4328700_17 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000334 198.0
HFD2_k127_4328700_18 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000001108 141.0
HFD2_k127_4328700_19 AMMECR1 K09141 - - 0.0000000000000000000000000000000005831 143.0
HFD2_k127_4328700_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.52e-247 784.0
HFD2_k127_4328700_20 Tetratricopeptide repeat - - - 0.00000000000000000000000000000008219 145.0
HFD2_k127_4328700_21 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000001333 132.0
HFD2_k127_4328700_22 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000005836 130.0
HFD2_k127_4328700_23 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000006048 128.0
HFD2_k127_4328700_24 - - - - 0.0000000000000000000000000005539 114.0
HFD2_k127_4328700_25 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.0000000000000000000000000041 130.0
HFD2_k127_4328700_26 positive regulation of growth rate - - - 0.000000000000000000000000007358 126.0
HFD2_k127_4328700_27 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000002201 112.0
HFD2_k127_4328700_28 PFAM Peptidase M22, glycoprotease K14742 - - 0.0000000000000000000000008198 114.0
HFD2_k127_4328700_29 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000002112 112.0
HFD2_k127_4328700_3 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 4.878e-224 722.0
HFD2_k127_4328700_30 - - - - 0.00000000000000000000000481 102.0
HFD2_k127_4328700_31 Thrombospondin type 3 repeat - - - 0.00000000000000000000008306 116.0
HFD2_k127_4328700_32 - - - - 0.000000000000000005593 88.0
HFD2_k127_4328700_33 Protein of unknown function (DUF503) K09764 - - 0.00000000000000005041 86.0
HFD2_k127_4328700_34 - - - - 0.00000000003298 64.0
HFD2_k127_4328700_35 unfolded protein binding K06142 - - 0.00000004323 62.0
HFD2_k127_4328700_36 ggdef domain - - - 0.00000007401 64.0
HFD2_k127_4328700_37 TonB C terminal - - - 0.000009931 57.0
HFD2_k127_4328700_4 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 411.0
HFD2_k127_4328700_5 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009685 303.0
HFD2_k127_4328700_6 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006627 297.0
HFD2_k127_4328700_7 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000006521 276.0
HFD2_k127_4328700_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000588 282.0
HFD2_k127_4328700_9 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001111 270.0
HFD2_k127_4333352_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008146 370.0
HFD2_k127_4333352_1 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 358.0
HFD2_k127_4333352_10 Tetratricopeptide repeat - - - 0.000000007055 66.0
HFD2_k127_4333352_11 DNA-binding helix-turn-helix protein - - - 0.00000362 54.0
HFD2_k127_4333352_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 337.0
HFD2_k127_4333352_3 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006228 270.0
HFD2_k127_4333352_4 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000001323 238.0
HFD2_k127_4333352_5 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000152 213.0
HFD2_k127_4333352_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000004067 201.0
HFD2_k127_4333352_7 Rhomboid family - - - 0.00000000000000000000000000000000000000000000003227 178.0
HFD2_k127_4333352_8 MFS_1 like family - - - 0.00000000000000000000000000000000001572 154.0
HFD2_k127_4333352_9 Thioredoxin-like - - - 0.000000000000000000000001369 119.0
HFD2_k127_4340438_0 DEAD DEAH box helicase - - - 0.0 1142.0
HFD2_k127_4340438_1 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 610.0
HFD2_k127_4340438_10 FAD dependent oxidoreductase K09471 - - 0.000000000000000000000000000000000000000000000000000008087 212.0
HFD2_k127_4340438_11 Methyltransferase domain K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000000000001176 199.0
HFD2_k127_4340438_12 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000003716 192.0
HFD2_k127_4340438_13 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000001111 186.0
HFD2_k127_4340438_14 RF-1 domain K15034 - - 0.000000000000000000000000000000000000000001337 163.0
HFD2_k127_4340438_15 - - - - 0.000000000000000001398 100.0
HFD2_k127_4340438_16 Calcium/calmodulin dependent protein kinase II association domain - - - 0.0000000004902 68.0
HFD2_k127_4340438_17 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000001669 66.0
HFD2_k127_4340438_18 Thioredoxin-like - - - 0.0000000118 59.0
HFD2_k127_4340438_19 PilZ domain - - - 0.0000001745 61.0
HFD2_k127_4340438_2 Belongs to the aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 517.0
HFD2_k127_4340438_3 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008516 389.0
HFD2_k127_4340438_4 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 372.0
HFD2_k127_4340438_5 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 354.0
HFD2_k127_4340438_6 amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 293.0
HFD2_k127_4340438_7 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009801 282.0
HFD2_k127_4340438_8 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001654 286.0
HFD2_k127_4340438_9 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000000000001179 246.0
HFD2_k127_4363128_0 Uncharacterized protein family (UPF0051) K09014 - - 7.721e-265 834.0
HFD2_k127_4363128_1 Prolyl oligopeptidase K01322 - 3.4.21.26 6.536e-212 681.0
HFD2_k127_4363128_10 protein conserved in bacteria K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 372.0
HFD2_k127_4363128_11 FeS assembly ATPase SufC K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000855 388.0
HFD2_k127_4363128_12 Ring hydroxylating alpha subunit (catalytic domain) K00479,K00499 - 1.14.15.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 363.0
HFD2_k127_4363128_13 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009787 348.0
HFD2_k127_4363128_14 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 359.0
HFD2_k127_4363128_15 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 338.0
HFD2_k127_4363128_16 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006292 291.0
HFD2_k127_4363128_17 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000002578 197.0
HFD2_k127_4363128_18 galactose-6-phosphate isomerase activity K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000005544 183.0
HFD2_k127_4363128_19 hydrolase of the alpha beta K07018 - - 0.000000000000000000000000000000000000000000001784 173.0
HFD2_k127_4363128_2 Cysteine desulfurase K01766,K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 552.0
HFD2_k127_4363128_20 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000008847 156.0
HFD2_k127_4363128_21 2 iron, 2 sulfur cluster binding - - - 0.000000000000000000000000000000000006878 142.0
HFD2_k127_4363128_22 PaaD-like protein - - - 0.0000000000000000000000000000000005625 136.0
HFD2_k127_4363128_23 Putative DNA-binding domain - - - 0.000000000000000000000000000000002647 145.0
HFD2_k127_4363128_24 PFAM flavin reductase domain protein FMN-binding K21185 - - 0.00000000000000000000000007439 123.0
HFD2_k127_4363128_25 Belongs to the peptidase S8 family - - - 0.000000000000000000003404 108.0
HFD2_k127_4363128_26 Domain of unknown function (DUF4198) - - - 0.00000000000000003327 93.0
HFD2_k127_4363128_27 TonB-dependent receptor plug domain protein K02014 - - 0.0000000000000009239 92.0
HFD2_k127_4363128_28 - - - - 0.0000000000005553 73.0
HFD2_k127_4363128_29 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 0.000000004214 63.0
HFD2_k127_4363128_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 529.0
HFD2_k127_4363128_30 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000003045 59.0
HFD2_k127_4363128_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K01719,K13542 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,4.1.1.37,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 428.0
HFD2_k127_4363128_5 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 428.0
HFD2_k127_4363128_6 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 417.0
HFD2_k127_4363128_7 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 405.0
HFD2_k127_4363128_8 protoporphyrinogen oxidase activity K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 410.0
HFD2_k127_4363128_9 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007714 380.0
HFD2_k127_4399562_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0 1396.0
HFD2_k127_4399562_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 396.0
HFD2_k127_4399562_10 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000003823 241.0
HFD2_k127_4399562_11 Tetratricopeptide repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002946 247.0
HFD2_k127_4399562_12 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000006644 229.0
HFD2_k127_4399562_14 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000000000000005152 193.0
HFD2_k127_4399562_15 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000005293 167.0
HFD2_k127_4399562_16 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000001286 168.0
HFD2_k127_4399562_17 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000002031 153.0
HFD2_k127_4399562_18 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000001775 128.0
HFD2_k127_4399562_19 methyltransferase activity - - - 0.0000000000000000000000000001579 123.0
HFD2_k127_4399562_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 389.0
HFD2_k127_4399562_20 Ferric uptake regulator family K09825 - - 0.0000000000000000000007732 102.0
HFD2_k127_4399562_21 Outer membrane efflux protein - - - 0.000000000000000000001079 110.0
HFD2_k127_4399562_22 Membrane - - - 0.0000000000000001358 87.0
HFD2_k127_4399562_23 bacterioferritin comigratory protein K03564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.11.1.15 0.000000000001206 71.0
HFD2_k127_4399562_24 Cupin domain - - - 0.00000000002237 69.0
HFD2_k127_4399562_26 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000007725 64.0
HFD2_k127_4399562_27 - - - - 0.0000000001308 72.0
HFD2_k127_4399562_28 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000002372 63.0
HFD2_k127_4399562_29 - - - - 0.0000000988 61.0
HFD2_k127_4399562_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 351.0
HFD2_k127_4399562_4 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 310.0
HFD2_k127_4399562_5 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 302.0
HFD2_k127_4399562_6 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000427 287.0
HFD2_k127_4399562_7 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006508 271.0
HFD2_k127_4399562_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001921 246.0
HFD2_k127_4399562_9 Iron-containing redox enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000002935 239.0
HFD2_k127_4419251_0 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 0.0 1109.0
HFD2_k127_4419251_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 1.097e-263 838.0
HFD2_k127_4419251_10 Metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000175 285.0
HFD2_k127_4419251_11 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002996 306.0
HFD2_k127_4419251_12 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000002192 249.0
HFD2_k127_4419251_13 AntiSigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000003064 224.0
HFD2_k127_4419251_14 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000002351 209.0
HFD2_k127_4419251_15 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000003078 184.0
HFD2_k127_4419251_16 OmpA family K02557 - - 0.0000000000000000000000000000000003642 141.0
HFD2_k127_4419251_18 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000009604 97.0
HFD2_k127_4419251_19 - - - - 0.000000000000007149 81.0
HFD2_k127_4419251_2 WD40 domain protein beta Propeller K12132 - 2.7.11.1 3.819e-209 680.0
HFD2_k127_4419251_20 CotH kinase protein - - - 0.0000106 58.0
HFD2_k127_4419251_3 TIGRFAM amino acid carrier protein K03310 - - 1.176e-195 624.0
HFD2_k127_4419251_4 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 611.0
HFD2_k127_4419251_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006383 407.0
HFD2_k127_4419251_6 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 359.0
HFD2_k127_4419251_7 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 324.0
HFD2_k127_4419251_8 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 323.0
HFD2_k127_4419251_9 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 312.0
HFD2_k127_4428926_0 aminopeptidase K01262 - 3.4.11.9 0.0000000000000000000003521 107.0
HFD2_k127_4432291_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 574.0
HFD2_k127_4432291_1 PFAM MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 517.0
HFD2_k127_4432291_10 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001776 267.0
HFD2_k127_4432291_11 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000004545 226.0
HFD2_k127_4432291_12 Protein kinase domain K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000001004 228.0
HFD2_k127_4432291_13 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000000000000000000000000000000000001066 220.0
HFD2_k127_4432291_14 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000253 207.0
HFD2_k127_4432291_15 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000001022 183.0
HFD2_k127_4432291_16 reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.0000000000000000000000000000000000000000000000002621 198.0
HFD2_k127_4432291_17 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000001848 181.0
HFD2_k127_4432291_18 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000002254 139.0
HFD2_k127_4432291_19 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000003094 129.0
HFD2_k127_4432291_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 496.0
HFD2_k127_4432291_20 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.000000000000000000000000004128 125.0
HFD2_k127_4432291_21 Pas domain - - - 0.0000000000000000000000000179 117.0
HFD2_k127_4432291_22 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.00000000000000000000000005764 124.0
HFD2_k127_4432291_23 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000006507 111.0
HFD2_k127_4432291_24 Phosphopantetheine attachment site K02078 - - 0.000000000000000000003403 96.0
HFD2_k127_4432291_25 bacterial OsmY and nodulation domain K04065 - - 0.000000000000000000005151 100.0
HFD2_k127_4432291_26 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.00000000000000007214 91.0
HFD2_k127_4432291_27 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000006169 83.0
HFD2_k127_4432291_28 Protein of unknown function (DUF1579) - - - 0.000000000001472 82.0
HFD2_k127_4432291_29 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000005775 67.0
HFD2_k127_4432291_3 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 499.0
HFD2_k127_4432291_30 Protein of unknown function (DUF1579) - - - 0.000000001912 72.0
HFD2_k127_4432291_31 Protein of unknown function (DUF2662) - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.00000001261 68.0
HFD2_k127_4432291_32 FabA-like domain - - - 0.0000004602 63.0
HFD2_k127_4432291_33 response regulator - - - 0.0000009386 59.0
HFD2_k127_4432291_34 dehydratase - - - 0.0001173 55.0
HFD2_k127_4432291_4 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 434.0
HFD2_k127_4432291_5 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 397.0
HFD2_k127_4432291_6 Di-haem cytochrome c peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 320.0
HFD2_k127_4432291_7 Cytochrome b(N-terminal)/b6/petB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009439 292.0
HFD2_k127_4432291_8 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001791 277.0
HFD2_k127_4432291_9 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000008621 267.0
HFD2_k127_4438883_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 6.033e-209 656.0
HFD2_k127_4438883_1 catalyzes the conversion of acetate and CoA to acetyl-CoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 565.0
HFD2_k127_4438883_10 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000004418 222.0
HFD2_k127_4438883_11 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000207 171.0
HFD2_k127_4438883_12 Glutathione S-transferase, C-terminal domain - - - 0.0000000000000000000000000000000000002065 153.0
HFD2_k127_4438883_13 Exonuclease - - - 0.00000000000000000000000000001895 130.0
HFD2_k127_4438883_14 COG0694 Thioredoxin-like proteins and domains - - - 0.000000000000000000000000003485 116.0
HFD2_k127_4438883_15 - - - - 0.0000000000000000000001949 111.0
HFD2_k127_4438883_16 guanyl-nucleotide exchange factor activity - - - 0.0000000000000000000005016 113.0
HFD2_k127_4438883_17 Dodecin K09165 - - 0.000000000000000000001157 106.0
HFD2_k127_4438883_18 Acid phosphatase homologues - - - 0.000000000000000000001649 106.0
HFD2_k127_4438883_19 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000006158 98.0
HFD2_k127_4438883_2 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 529.0
HFD2_k127_4438883_20 - - - - 0.00000000000000000006811 105.0
HFD2_k127_4438883_21 MATE efflux family protein - - - 0.0000000000000004054 91.0
HFD2_k127_4438883_22 alginic acid biosynthetic process K01729,K17713 - 4.2.2.3 0.0000000006054 74.0
HFD2_k127_4438883_23 Putative metal-binding motif - - - 0.000000004083 68.0
HFD2_k127_4438883_24 ABC transporter K06158 - - 0.000002425 55.0
HFD2_k127_4438883_25 peptidylprolyl isomerase K03769 - 5.2.1.8 0.00001018 55.0
HFD2_k127_4438883_26 Phosphopantetheine attachment site - - - 0.0002036 47.0
HFD2_k127_4438883_3 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 478.0
HFD2_k127_4438883_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000667 469.0
HFD2_k127_4438883_5 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007801 408.0
HFD2_k127_4438883_6 Response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 378.0
HFD2_k127_4438883_7 belongs to the iron- containing alcohol dehydrogenase family K04072 - 1.1.1.1,1.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006767 376.0
HFD2_k127_4438883_8 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002106 258.0
HFD2_k127_4438883_9 Prephenate dehydrogenase chorismate mutase K00210 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000001192 234.0
HFD2_k127_444865_0 Acyl transferase domain - - - 0.0 1763.0
HFD2_k127_444865_1 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 290.0
HFD2_k127_444865_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000007204 199.0
HFD2_k127_444865_3 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000597 110.0
HFD2_k127_444865_4 Transposase - - - 0.000000000000000000000002068 109.0
HFD2_k127_444865_5 Amidinotransferase K01478 - 3.5.3.6 0.00000000000000000000003015 115.0
HFD2_k127_444865_6 DDE superfamily endonuclease - - - 0.000004227 56.0
HFD2_k127_4487280_0 C-terminus of AA_permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 467.0
HFD2_k127_4487280_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 323.0
HFD2_k127_4491565_0 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 497.0
HFD2_k127_4491565_1 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000001172 240.0
HFD2_k127_4491565_2 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000006727 177.0
HFD2_k127_4491565_3 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.00000000000000000000000000000000000000009378 167.0
HFD2_k127_4531842_0 ABC transporter - - - 4.947e-255 797.0
HFD2_k127_4531842_1 helicase activity - - - 1.516e-249 793.0
HFD2_k127_4531842_2 X-Pro dipeptidyl-peptidase (S15 family) - - - 1.861e-213 685.0
HFD2_k127_4531842_3 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 496.0
HFD2_k127_4531842_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 413.0
HFD2_k127_4531842_5 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 373.0
HFD2_k127_4531842_6 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008596 316.0
HFD2_k127_4531842_7 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001248 222.0
HFD2_k127_4531842_8 cellulase activity K20276 - - 0.000000009326 70.0
HFD2_k127_4560839_0 CAAX protease self-immunity K07052 - - 0.00000000000000000000001918 110.0
HFD2_k127_4560839_1 Peptidase family M23 K01406 - 3.4.24.40 0.0000000000003958 80.0
HFD2_k127_4574676_0 AcrB/AcrD/AcrF family - - - 7.092e-252 812.0
HFD2_k127_4574676_1 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 2.149e-235 755.0
HFD2_k127_4574676_10 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 354.0
HFD2_k127_4574676_11 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate K03856,K13853 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 359.0
HFD2_k127_4574676_12 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 369.0
HFD2_k127_4574676_13 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 368.0
HFD2_k127_4574676_14 Transcriptional regulatory protein, C terminal K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 331.0
HFD2_k127_4574676_15 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001771 280.0
HFD2_k127_4574676_16 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007364 280.0
HFD2_k127_4574676_17 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005406 252.0
HFD2_k127_4574676_18 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000003048 215.0
HFD2_k127_4574676_19 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000000000007584 184.0
HFD2_k127_4574676_2 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 622.0
HFD2_k127_4574676_20 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.00000000000000000000000000000000000000000001638 171.0
HFD2_k127_4574676_21 deoxyhypusine monooxygenase activity K01256 - 3.4.11.2 0.000000000000000000000000000000000000000002756 169.0
HFD2_k127_4574676_22 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000003994 125.0
HFD2_k127_4574676_23 oxidation-reduction process - - - 0.0000000000000000000000006027 124.0
HFD2_k127_4574676_24 Outer membrane efflux protein K15725 - - 0.00000000000000000000003025 114.0
HFD2_k127_4574676_25 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0000988,GO:0000990,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000001104 99.0
HFD2_k127_4574676_26 - - - - 0.0000000000000000001645 102.0
HFD2_k127_4574676_27 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000001016 85.0
HFD2_k127_4574676_28 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.5.1.16 0.0000000000001125 86.0
HFD2_k127_4574676_29 - - - - 0.00004094 54.0
HFD2_k127_4574676_3 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000958 443.0
HFD2_k127_4574676_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 450.0
HFD2_k127_4574676_5 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 451.0
HFD2_k127_4574676_6 Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 434.0
HFD2_k127_4574676_7 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005782 411.0
HFD2_k127_4574676_8 Cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007776 374.0
HFD2_k127_4574676_9 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 345.0
HFD2_k127_4576372_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0 1052.0
HFD2_k127_4576372_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006272 616.0
HFD2_k127_4576372_10 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 418.0
HFD2_k127_4576372_11 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 389.0
HFD2_k127_4576372_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 402.0
HFD2_k127_4576372_13 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 369.0
HFD2_k127_4576372_14 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 326.0
HFD2_k127_4576372_15 ApbE family K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 316.0
HFD2_k127_4576372_16 PFAM peptidase M16 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 312.0
HFD2_k127_4576372_17 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 291.0
HFD2_k127_4576372_18 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003872 276.0
HFD2_k127_4576372_19 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008806 282.0
HFD2_k127_4576372_2 Aminotransferase class-III K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007359 559.0
HFD2_k127_4576372_20 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001258 275.0
HFD2_k127_4576372_21 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001671 282.0
HFD2_k127_4576372_22 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000003454 284.0
HFD2_k127_4576372_23 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000308 269.0
HFD2_k127_4576372_24 deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000000002208 228.0
HFD2_k127_4576372_25 PD-(D/E)XK nuclease superfamily K03657,K07465 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000003702 234.0
HFD2_k127_4576372_26 Protein of unknown function (DUF3570) - - - 0.0000000000000000000000000000000000000000000000000000000000007209 231.0
HFD2_k127_4576372_27 helix_turn_helix, Lux Regulon K11618 - - 0.000000000000000000000000000000000000000000000000000000000006368 217.0
HFD2_k127_4576372_28 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005576 - 0.000000000000000000000000000000000000000009163 161.0
HFD2_k127_4576372_29 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.0000000000000000000000000000000000000001354 156.0
HFD2_k127_4576372_3 Belongs to the aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 556.0
HFD2_k127_4576372_30 Redoxin - - - 0.000000000000000000000000000000000000001881 154.0
HFD2_k127_4576372_31 EamA-like transporter family - - - 0.00000000000000000000000000000000003577 156.0
HFD2_k127_4576372_33 EVE domain - - - 0.00000000000000000000000000000000006604 137.0
HFD2_k127_4576372_34 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02658 - - 0.000000000000000000000000000003623 137.0
HFD2_k127_4576372_35 ATP synthesis coupled proton transport K02109 - - 0.000000000000000000000000000006176 125.0
HFD2_k127_4576372_36 Zincin-like metallopeptidase - - - 0.000000000000000000000000000006548 123.0
HFD2_k127_4576372_37 - K01992,K19341 - - 0.00000000000000000000000000003767 134.0
HFD2_k127_4576372_38 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000002183 134.0
HFD2_k127_4576372_39 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K01838 - 5.4.2.6 0.0000000000000000000000001197 115.0
HFD2_k127_4576372_4 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00821,K05830,K09251 - 2.6.1.11,2.6.1.17,2.6.1.82 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 551.0
HFD2_k127_4576372_40 Cold shock K03704 - - 0.00000000000000000000007127 111.0
HFD2_k127_4576372_41 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000001115 100.0
HFD2_k127_4576372_42 5'-nucleotidase - - - 0.00000000000000000003209 106.0
HFD2_k127_4576372_43 Protein of unknown function DUF86 - - - 0.00000000000000000004094 94.0
HFD2_k127_4576372_44 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000001345 91.0
HFD2_k127_4576372_45 - - - - 0.000000000000000067 85.0
HFD2_k127_4576372_46 Tetratricopeptide repeat - - - 0.0000000000000001311 93.0
HFD2_k127_4576372_47 Domain of unknown function (DUF4266) - - - 0.0000000000000003269 88.0
HFD2_k127_4576372_48 Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c - - - 0.00000000000001126 88.0
HFD2_k127_4576372_49 Belongs to the peptidase S8 family - - - 0.0000000000000237 88.0
HFD2_k127_4576372_5 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 478.0
HFD2_k127_4576372_51 bacterial OsmY and nodulation domain K04065 - - 0.0000000002719 71.0
HFD2_k127_4576372_52 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000006639 59.0
HFD2_k127_4576372_53 Tetratricopeptide repeat - - - 0.000002907 54.0
HFD2_k127_4576372_54 deoxyhypusine monooxygenase activity - - - 0.000002954 62.0
HFD2_k127_4576372_55 DnaJ molecular chaperone homology domain - - - 0.00003634 54.0
HFD2_k127_4576372_56 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.0000418 49.0
HFD2_k127_4576372_57 amine dehydrogenase activity - - - 0.00008883 57.0
HFD2_k127_4576372_58 Belongs to the peptidase S8 family - - - 0.00011 53.0
HFD2_k127_4576372_6 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 462.0
HFD2_k127_4576372_7 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 453.0
HFD2_k127_4576372_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 473.0
HFD2_k127_4576372_9 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K09251 - 2.6.1.82 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 434.0
HFD2_k127_4585812_0 Cytochrome C assembly protein - - - 1.865e-243 778.0
HFD2_k127_4585812_1 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 593.0
HFD2_k127_4585812_10 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 377.0
HFD2_k127_4585812_11 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 372.0
HFD2_k127_4585812_12 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 346.0
HFD2_k127_4585812_13 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 354.0
HFD2_k127_4585812_14 Lipid A Biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 324.0
HFD2_k127_4585812_15 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000003235 291.0
HFD2_k127_4585812_16 collagen metabolic process K08677 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006258 282.0
HFD2_k127_4585812_17 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000001465 252.0
HFD2_k127_4585812_18 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000005464 218.0
HFD2_k127_4585812_19 Thiazolinyl imide reductase K04785 - - 0.00000000000000000000000000000000000003036 156.0
HFD2_k127_4585812_2 Catalyzes the interconversion of ornithine to glutamate semialdehyde K00819 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 574.0
HFD2_k127_4585812_20 N-formylglutamate amidohydrolase - - - 0.0000000000000000000000000000000003294 148.0
HFD2_k127_4585812_21 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000445 136.0
HFD2_k127_4585812_22 phosphorelay signal transduction system K02437 - - 0.0000000000000000006917 94.0
HFD2_k127_4585812_23 PFAM thioesterase superfamily K02614 - - 0.000000000000000001073 91.0
HFD2_k127_4585812_24 - - - - 0.00000000000007494 74.0
HFD2_k127_4585812_25 heme-binding sites - - - 0.0000000004026 67.0
HFD2_k127_4585812_3 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 558.0
HFD2_k127_4585812_4 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005665 522.0
HFD2_k127_4585812_5 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 495.0
HFD2_k127_4585812_6 phosphorelay signal transduction system K02437 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 469.0
HFD2_k127_4585812_7 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005875 447.0
HFD2_k127_4585812_8 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000857 441.0
HFD2_k127_4585812_9 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006042 426.0
HFD2_k127_4595171_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 5.95e-200 659.0
HFD2_k127_4595171_1 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 508.0
HFD2_k127_4595171_10 PFAM OmpA MotB domain protein K02557 - - 0.00000000000000000000000000000000005404 145.0
HFD2_k127_4595171_11 nUDIX hydrolase K01515,K03574,K03801,K08310 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008828,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017144,GO:0018130,GO:0019177,GO:0019438,GO:0019752,GO:0034641,GO:0042364,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0046872,GO:0047429,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.181,3.6.1.13,3.6.1.55,3.6.1.67 0.000000000000000000000001277 120.0
HFD2_k127_4595171_12 - - - - 0.000000000000000000000004597 105.0
HFD2_k127_4595171_13 Thioredoxin-like K02199 - - 0.0000000000000000000002248 112.0
HFD2_k127_4595171_15 Thrombospondin type 3 repeat - - - 0.00000000000000000001085 108.0
HFD2_k127_4595171_16 Metallo-peptidase family M12B Reprolysin-like - - - 0.000000000000000008315 99.0
HFD2_k127_4595171_17 - - - - 0.000000000000004185 79.0
HFD2_k127_4595171_19 - - - - 0.0000000003122 70.0
HFD2_k127_4595171_2 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 378.0
HFD2_k127_4595171_20 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000002513 68.0
HFD2_k127_4595171_21 - - - - 0.0000003441 63.0
HFD2_k127_4595171_22 Heavy-metal resistance - - - 0.00002482 55.0
HFD2_k127_4595171_23 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00003893 56.0
HFD2_k127_4595171_24 Heavy-metal-associated domain K17686 - 3.6.3.54 0.0001822 52.0
HFD2_k127_4595171_25 Transglutaminase-like superfamily - - - 0.0002249 55.0
HFD2_k127_4595171_3 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 367.0
HFD2_k127_4595171_4 Iron/manganese superoxide dismutases, alpha-hairpin domain K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000005713 252.0
HFD2_k127_4595171_5 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000006083 231.0
HFD2_k127_4595171_6 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000009848 221.0
HFD2_k127_4595171_7 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000105 203.0
HFD2_k127_4595171_8 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.000000000000000000000000000000000000000002195 172.0
HFD2_k127_4595171_9 YceI-like domain - - - 0.000000000000000000000000000000000000000002759 175.0
HFD2_k127_4611375_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1035.0
HFD2_k127_4611375_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.048e-254 794.0
HFD2_k127_4611375_10 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 394.0
HFD2_k127_4611375_11 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 338.0
HFD2_k127_4611375_12 Belongs to the KdsA family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 342.0
HFD2_k127_4611375_13 Evidence 4 Homologs of previously reported genes of K09927 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 353.0
HFD2_k127_4611375_14 Response receiver-modulated cyclic diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 336.0
HFD2_k127_4611375_15 Belongs to the SIS family. GutQ KpsF subfamily K01627,K03281,K06041 - 2.5.1.55,5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 339.0
HFD2_k127_4611375_16 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006155 304.0
HFD2_k127_4611375_17 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369,K13890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006493 287.0
HFD2_k127_4611375_18 PFAM dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005054 286.0
HFD2_k127_4611375_19 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001711 277.0
HFD2_k127_4611375_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.514e-238 788.0
HFD2_k127_4611375_20 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007031 269.0
HFD2_k127_4611375_21 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000001575 241.0
HFD2_k127_4611375_22 PFAM Proprotein convertase P-domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001982 255.0
HFD2_k127_4611375_23 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000642 238.0
HFD2_k127_4611375_24 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000001226 229.0
HFD2_k127_4611375_25 Glycosyltransferase family 28 N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000001336 219.0
HFD2_k127_4611375_26 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000005939 226.0
HFD2_k127_4611375_27 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000002997 220.0
HFD2_k127_4611375_28 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000001856 213.0
HFD2_k127_4611375_29 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000007578 186.0
HFD2_k127_4611375_3 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.517e-218 690.0
HFD2_k127_4611375_30 PFAM glycosyl transferase family 9 K02841 - - 0.000000000000000000000000000000000000000000000002336 187.0
HFD2_k127_4611375_31 Peroxiredoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000003577 174.0
HFD2_k127_4611375_32 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000678 177.0
HFD2_k127_4611375_33 SurA N-terminal domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000227 175.0
HFD2_k127_4611375_34 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K01627,K03270 - 2.5.1.55,3.1.3.45 0.000000000000000000000000000000000000000001191 164.0
HFD2_k127_4611375_35 - - - - 0.0000000000000000000000000000000000002409 151.0
HFD2_k127_4611375_36 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000000001076 148.0
HFD2_k127_4611375_37 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000003097 137.0
HFD2_k127_4611375_38 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.0000000000000000000000000000000002165 137.0
HFD2_k127_4611375_39 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00658 - 2.3.1.61 0.0000000000000000000000000000000005835 138.0
HFD2_k127_4611375_4 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 537.0
HFD2_k127_4611375_40 NifU-like N terminal domain - - - 0.00000000000000000000000000000003381 133.0
HFD2_k127_4611375_41 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.0000000000000000000000000000007727 143.0
HFD2_k127_4611375_42 Belongs to the peptidase S8 family K01173 - - 0.000000000000000000000000001036 132.0
HFD2_k127_4611375_43 Alpha/beta hydrolase family - - - 0.000000000000000000000000384 115.0
HFD2_k127_4611375_45 Domain of unknown function (DUF4388) - - - 0.00000000000000000000002111 109.0
HFD2_k127_4611375_46 COG2146 Ferredoxin subunits of nitrite reductase and K00363 - 1.7.1.15 0.00000000000000001082 94.0
HFD2_k127_4611375_47 NADH ubiquinone oxidoreductase K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 0.00000000000000007036 86.0
HFD2_k127_4611375_48 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.00000000000000007468 89.0
HFD2_k127_4611375_49 Trm112p-like protein K00912,K09791 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.1.130 0.0000000000000004111 79.0
HFD2_k127_4611375_5 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 471.0
HFD2_k127_4611375_50 - - - - 0.000000000000003439 80.0
HFD2_k127_4611375_51 mttA/Hcf106 family K03116 - - 0.000000000004355 72.0
HFD2_k127_4611375_53 Domain of unknown function (DUF4382) - - - 0.000000004807 66.0
HFD2_k127_4611375_54 Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position K11211 - 2.7.1.166 0.00000001896 67.0
HFD2_k127_4611375_55 DNA-templated transcription, initiation - - - 0.00000003855 57.0
HFD2_k127_4611375_56 transcriptional regulator, SARP family - - - 0.000008507 58.0
HFD2_k127_4611375_57 Hep Hag repeat protein - - - 0.0000243 57.0
HFD2_k127_4611375_58 - - - - 0.00005574 56.0
HFD2_k127_4611375_59 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.0005888 47.0
HFD2_k127_4611375_6 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 436.0
HFD2_k127_4611375_7 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 426.0
HFD2_k127_4611375_8 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 388.0
HFD2_k127_4611375_9 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 387.0
HFD2_k127_4612250_0 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006346 403.0
HFD2_k127_4612250_1 endonuclease activity K07451 - - 0.0000000000000000000000000000000000000000000000000000000000004601 237.0
HFD2_k127_4612250_2 cellulose 1,4-beta-cellobiosidase activity K01278,K01727,K03561,K12287,K21449 - 3.4.14.5,4.2.2.1 0.00000000000000000000000000000000000000000215 168.0
HFD2_k127_4612250_3 cellulose 1,4-beta-cellobiosidase activity K01278,K01727,K03561,K12287,K21449 - 3.4.14.5,4.2.2.1 0.000000000000000000000000000000008746 130.0
HFD2_k127_4639882_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 538.0
HFD2_k127_4639882_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03851,K15372 - 2.6.1.55,2.6.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 472.0
HFD2_k127_4639882_10 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 314.0
HFD2_k127_4639882_11 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 306.0
HFD2_k127_4639882_12 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 306.0
HFD2_k127_4639882_13 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006896 312.0
HFD2_k127_4639882_14 conserved protein (COG2071) K09166 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003692 254.0
HFD2_k127_4639882_15 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000001055 250.0
HFD2_k127_4639882_16 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000002523 275.0
HFD2_k127_4639882_17 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000281 254.0
HFD2_k127_4639882_18 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000284 266.0
HFD2_k127_4639882_19 Domain of unknown function (4846) - - - 0.00000000000000000000000000000000000000000000000000000001093 211.0
HFD2_k127_4639882_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009016 441.0
HFD2_k127_4639882_20 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000009102 209.0
HFD2_k127_4639882_21 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000008977 163.0
HFD2_k127_4639882_22 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000001026 149.0
HFD2_k127_4639882_23 Cell division protein FtsQ K03589 - - 0.00000000000000000006855 102.0
HFD2_k127_4639882_24 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000009297 82.0
HFD2_k127_4639882_25 PFAM Integrase catalytic region K07497 - - 0.000000002875 59.0
HFD2_k127_4639882_26 D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.0000008066 51.0
HFD2_k127_4639882_27 Evidence 5 No homology to any previously reported sequences - - - 0.0008686 51.0
HFD2_k127_4639882_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 422.0
HFD2_k127_4639882_4 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 430.0
HFD2_k127_4639882_5 amino acid K03294,K13868 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 411.0
HFD2_k127_4639882_6 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 410.0
HFD2_k127_4639882_7 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 419.0
HFD2_k127_4639882_8 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 385.0
HFD2_k127_4639882_9 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 365.0
HFD2_k127_4640124_0 Prolyl oligopeptidase family K01303 - 3.4.19.1 2.744e-236 754.0
HFD2_k127_4640124_1 PFAM multicopper oxidase type 2 - - - 2.875e-227 728.0
HFD2_k127_4640124_10 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 354.0
HFD2_k127_4640124_11 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 358.0
HFD2_k127_4640124_12 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 321.0
HFD2_k127_4640124_13 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008211 319.0
HFD2_k127_4640124_14 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001131 271.0
HFD2_k127_4640124_15 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000000001484 230.0
HFD2_k127_4640124_16 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000002411 213.0
HFD2_k127_4640124_17 B12 binding domain K14084 - - 0.0000000000000000000000000000000000000000000000000000001097 204.0
HFD2_k127_4640124_18 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000005458 217.0
HFD2_k127_4640124_19 - - - - 0.0000000000000000000000000000000000000000000000000000005765 201.0
HFD2_k127_4640124_2 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 487.0
HFD2_k127_4640124_20 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000003449 177.0
HFD2_k127_4640124_21 Putative transposase - - - 0.000000000000000000000000000000000000000003058 173.0
HFD2_k127_4640124_22 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000001133 145.0
HFD2_k127_4640124_23 methyltransferase activity - - - 0.00000000000000000000000000000009363 133.0
HFD2_k127_4640124_24 oligosaccharyl transferase activity - - - 0.000000000000000000000000005675 128.0
HFD2_k127_4640124_25 Cold shock K03704 - - 0.00000000000000000000000001138 110.0
HFD2_k127_4640124_26 Cytochrome c K02720 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.000000000000000000000000185 114.0
HFD2_k127_4640124_27 RNA recognition motif - - - 0.00000000000000000000003601 105.0
HFD2_k127_4640124_28 Putative Ig domain - - - 0.0000000000000000001522 106.0
HFD2_k127_4640124_29 transcriptional regulator - - - 0.0000000000000000003253 97.0
HFD2_k127_4640124_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738,K17216 - 2.5.1.134,2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 467.0
HFD2_k127_4640124_30 Thrombospondin type 3 repeat - - - 0.000000000000006685 90.0
HFD2_k127_4640124_31 Uncharacterised nucleotidyltransferase - - - 0.0000000000004901 81.0
HFD2_k127_4640124_32 translation initiation factor activity K03699 - - 0.0000000000008451 77.0
HFD2_k127_4640124_33 regulator of chromosome condensation, RCC1 - - - 0.0000000003189 74.0
HFD2_k127_4640124_34 Thrombospondin type 3 repeat - - - 0.00000003668 66.0
HFD2_k127_4640124_35 Transposase - - - 0.0000002078 63.0
HFD2_k127_4640124_36 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01179 - 3.2.1.4 0.0000004037 64.0
HFD2_k127_4640124_37 Elongation factor G, domain IV K02355 - - 0.000001025 56.0
HFD2_k127_4640124_38 Sigma-54 interaction domain K07712 - - 0.0001978 49.0
HFD2_k127_4640124_4 asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 406.0
HFD2_k127_4640124_5 C-terminal domain of 1-Cys peroxiredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009655 396.0
HFD2_k127_4640124_6 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 415.0
HFD2_k127_4640124_7 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 385.0
HFD2_k127_4640124_8 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 386.0
HFD2_k127_4640124_9 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009386 376.0
HFD2_k127_4646629_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 634.0
HFD2_k127_4646629_1 cystathionine gamma-synthase activity K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 554.0
HFD2_k127_4646629_10 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000004673 160.0
HFD2_k127_4646629_11 PFAM ABC transporter K02003 - - 0.0000000000000000000000000000000000000004771 150.0
HFD2_k127_4646629_12 methylated-DNA- protein -cysteine S-methyltransferase K00567 - 2.1.1.63 0.0000000000000000000000004857 120.0
HFD2_k127_4646629_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000000000956 114.0
HFD2_k127_4646629_14 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000004189 97.0
HFD2_k127_4646629_15 Belongs to the peptidase S1C family K04691,K04771,K04772 - 3.4.21.107 0.0000000002015 69.0
HFD2_k127_4646629_16 Trypsin K04771 - 3.4.21.107 0.0000000005568 69.0
HFD2_k127_4646629_2 GMP synthase (glutamine-hydrolyzing) activity K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 448.0
HFD2_k127_4646629_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 408.0
HFD2_k127_4646629_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 396.0
HFD2_k127_4646629_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004821 280.0
HFD2_k127_4646629_6 Oxygenase, catalysing oxidative methylation of damaged DNA K09990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001134 287.0
HFD2_k127_4646629_7 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001555 271.0
HFD2_k127_4646629_8 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005787 269.0
HFD2_k127_4646629_9 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000001035 267.0
HFD2_k127_4663388_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0 1142.0
HFD2_k127_4663388_1 Peptidase family M1 domain - - - 5.94e-254 795.0
HFD2_k127_4663388_10 FR47-like protein - - - 0.0000000000000000000000001865 107.0
HFD2_k127_4663388_11 outer membrane efflux protein K15725 - - 0.0000000001326 74.0
HFD2_k127_4663388_2 Tricorn protease C1 domain K08676 - - 1.648e-204 676.0
HFD2_k127_4663388_3 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007816 512.0
HFD2_k127_4663388_4 fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 397.0
HFD2_k127_4663388_5 Flavin containing amine oxidoreductase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 384.0
HFD2_k127_4663388_6 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 346.0
HFD2_k127_4663388_7 - K12065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006701 264.0
HFD2_k127_4663388_8 Barrel-sandwich domain of CusB or HlyD membrane-fusion K15727 - - 0.0000000000000000000000000000000000000000000138 185.0
HFD2_k127_4663388_9 - - - - 0.000000000000000000000000000000000000001038 166.0
HFD2_k127_4707491_0 ABC transporter - - - 1.198e-290 901.0
HFD2_k127_4707491_1 Beta-lactamase enzyme family K07262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009858 276.0
HFD2_k127_4707491_2 UPF0314 protein - - - 0.00000000000000000000000000000000000000000003938 183.0
HFD2_k127_4707491_3 Protein of unknown function (DUF3617) - - - 0.00000000000000000001424 103.0
HFD2_k127_4707491_4 - - - - 0.00005907 53.0
HFD2_k127_4791813_0 Belongs to the RtcB family K14415 - 6.5.1.3 2.174e-203 649.0
HFD2_k127_4791813_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 556.0
HFD2_k127_4791813_2 Phosphate acyltransferases K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 453.0
HFD2_k127_4791813_3 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002297 294.0
HFD2_k127_4791813_4 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000000000000000003112 91.0
HFD2_k127_4791813_5 Belongs to the 'phage' integrase family - GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0008979,GO:0009009,GO:0009987,GO:0015074,GO:0016032,GO:0019042,GO:0019043,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051704,GO:0071704,GO:0075713,GO:0090304,GO:0140097,GO:1901360 - 0.0000000000000000383 85.0
HFD2_k127_4791813_6 Protein of unknown function (DUF2752) - - - 0.000000001037 65.0
HFD2_k127_4800643_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.169e-266 844.0
HFD2_k127_4800643_1 copper-translocating P-type ATPase K17686 - 3.6.3.54 4.986e-237 760.0
HFD2_k127_4800643_10 tetratricopeptide repeat - - - 0.00000000000003068 84.0
HFD2_k127_4800643_11 glyoxalase III activity - - - 0.00000000008414 74.0
HFD2_k127_4800643_2 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 346.0
HFD2_k127_4800643_3 Belongs to the arginase family K01476,K01480 - 3.5.3.1,3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000054 256.0
HFD2_k127_4800643_4 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000001458 248.0
HFD2_k127_4800643_5 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000001148 198.0
HFD2_k127_4800643_6 Peptidase dimerisation domain K12941 - - 0.0000000000000000000000000000000000000000000008631 170.0
HFD2_k127_4800643_7 exonuclease activity K16899 - 3.6.4.12 0.00000000000000000000000000000000008705 155.0
HFD2_k127_4800643_8 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000001585 137.0
HFD2_k127_4800643_9 - - - - 0.000000000000000004277 99.0
HFD2_k127_4805492_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 535.0
HFD2_k127_4805492_1 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 482.0
HFD2_k127_4805492_10 cell cycle K05589,K12065,K13052 - - 0.0003693 53.0
HFD2_k127_4805492_11 Tetratricopeptide repeats - - - 0.0008114 50.0
HFD2_k127_4805492_2 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 375.0
HFD2_k127_4805492_3 Peptidase M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006315 299.0
HFD2_k127_4805492_4 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000006173 246.0
HFD2_k127_4805492_5 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000002342 106.0
HFD2_k127_4805492_6 - - - - 0.00000000000000000000241 98.0
HFD2_k127_4805492_7 translation initiation factor activity K03699 - - 0.0000000000000166 83.0
HFD2_k127_4805492_8 - - - - 0.0000000007458 59.0
HFD2_k127_484049_0 His Kinase A (phosphoacceptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 639.0
HFD2_k127_484049_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001754 294.0
HFD2_k127_484049_2 helicase K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003335 277.0
HFD2_k127_484049_3 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000001857 155.0
HFD2_k127_484049_4 Domain of unknown function (DUF4154) - - - 0.0000000000000000000000000003025 123.0
HFD2_k127_4846251_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1170.0
HFD2_k127_4846251_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.044e-301 936.0
HFD2_k127_4846251_10 conserved protein UCP033924 - - - 0.00000000000000000000000000000000000000000000000287 177.0
HFD2_k127_4846251_11 Belongs to the peptidase S8 family K13275 - - 0.0000000000000000000000000000000000002291 158.0
HFD2_k127_4846251_12 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000002885 160.0
HFD2_k127_4846251_13 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007,K21787 - 2.7.9.2 0.000000000000000000000000000000003066 151.0
HFD2_k127_4846251_14 Tetratricopeptide repeat - - - 0.000000000000000000000000000000009084 147.0
HFD2_k127_4846251_15 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000001166 141.0
HFD2_k127_4846251_16 NlpC/P60 family - - - 0.00000000000000000000000000003608 121.0
HFD2_k127_4846251_17 Peptidase MA superfamily - - - 0.0000000000000000000005409 113.0
HFD2_k127_4846251_18 Regulatory protein, FmdB - - - 0.00000000000000007276 96.0
HFD2_k127_4846251_2 malic enzyme K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 674.0
HFD2_k127_4846251_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 459.0
HFD2_k127_4846251_4 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 456.0
HFD2_k127_4846251_5 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 491.0
HFD2_k127_4846251_6 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 441.0
HFD2_k127_4846251_7 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 330.0
HFD2_k127_4846251_8 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009451 286.0
HFD2_k127_4846251_9 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000539 243.0
HFD2_k127_4865640_0 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 518.0
HFD2_k127_4865640_1 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 396.0
HFD2_k127_4865640_11 Chain length determinant protein K16554 - - 0.000000000000003238 91.0
HFD2_k127_4865640_12 -O-antigen K03641 - - 0.0000000002912 75.0
HFD2_k127_4865640_13 Acetyltransferase (GNAT) domain - - - 0.00000003581 67.0
HFD2_k127_4865640_14 SMART RNA-processing protein HAT helix repeating-containing protein - - - 0.0000005365 64.0
HFD2_k127_4865640_2 Domain of unknown function (DUF1972) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 308.0
HFD2_k127_4865640_3 Belongs to the peptidase S8 family K17734 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003605 283.0
HFD2_k127_4865640_4 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000003933 192.0
HFD2_k127_4865640_5 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000007241 193.0
HFD2_k127_4865640_6 Glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000001026 181.0
HFD2_k127_4865640_7 PFAM Polysaccharide biosynthesis export protein K01991 - - 0.00000000000000000000000000000000000000000002654 179.0
HFD2_k127_4865640_8 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.0000000000000000000000000000001883 138.0
HFD2_k127_4865640_9 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000004549 117.0
HFD2_k127_4918266_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 416.0
HFD2_k127_4918266_1 Putative restriction endonuclease - - - 0.0000000000000000000000000001631 122.0
HFD2_k127_4918266_2 ABC-type sugar transport system periplasmic component K02058,K10439 - - 0.0000000000000000000005641 106.0
HFD2_k127_4921423_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 612.0
HFD2_k127_4921423_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 548.0
HFD2_k127_4921423_10 tRNA processing K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000001467 242.0
HFD2_k127_4921423_11 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000009143 229.0
HFD2_k127_4921423_12 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000001037 233.0
HFD2_k127_4921423_13 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000005455 218.0
HFD2_k127_4921423_14 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000000784 196.0
HFD2_k127_4921423_15 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000003085 199.0
HFD2_k127_4921423_16 Diguanylate cyclase with GAF sensor - - - 0.0000000000000000000000000000000000000000000001414 182.0
HFD2_k127_4921423_17 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000002555 179.0
HFD2_k127_4921423_18 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000002769 183.0
HFD2_k127_4921423_19 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000001798 169.0
HFD2_k127_4921423_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 428.0
HFD2_k127_4921423_20 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000002473 170.0
HFD2_k127_4921423_21 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000005103 178.0
HFD2_k127_4921423_22 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000003051 153.0
HFD2_k127_4921423_23 FIST C domain - - - 0.00000000000000000000000000000000000000444 162.0
HFD2_k127_4921423_24 Outer membrane receptor - - - 0.000000000000000000000000000000000000008894 169.0
HFD2_k127_4921423_25 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000225 157.0
HFD2_k127_4921423_26 cytochrome oxidase assembly K02259 - - 0.00000000000000000000000000000001261 141.0
HFD2_k127_4921423_27 Thrombospondin type 3 repeat - - - 0.000000000000000000000000000000258 146.0
HFD2_k127_4921423_28 Protein of unknown function (DUF420) K08976 - - 0.000000000000000000000000000001472 136.0
HFD2_k127_4921423_29 Protein conserved in bacteria K09931 - - 0.000000000000000000000000001735 122.0
HFD2_k127_4921423_3 belongs to the thioredoxin family K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 436.0
HFD2_k127_4921423_30 cytochrome c oxidase cbb3-type, subunit II K00405 - - 0.0000000000000000000001304 112.0
HFD2_k127_4921423_31 peptidyl-tyrosine sulfation - - - 0.0000000000000000000008595 108.0
HFD2_k127_4921423_32 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000002921 93.0
HFD2_k127_4921423_33 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000004314 92.0
HFD2_k127_4921423_34 MobA-like NTP transferase domain K03752 - 2.7.7.77 0.0000000000001175 82.0
HFD2_k127_4921423_35 Unextendable partial coding region - - - 0.0000000000001833 76.0
HFD2_k127_4921423_36 Transcriptional regulator K07665 - - 0.000000000003469 80.0
HFD2_k127_4921423_37 EamA-like transporter family - - - 0.000000001504 67.0
HFD2_k127_4921423_39 Tetratricopeptide repeat - - - 0.00000009034 66.0
HFD2_k127_4921423_4 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 417.0
HFD2_k127_4921423_40 OmpW family K07275,K16079 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000001013 61.0
HFD2_k127_4921423_42 Subtilase family - - - 0.000007711 62.0
HFD2_k127_4921423_5 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 326.0
HFD2_k127_4921423_6 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000662 328.0
HFD2_k127_4921423_7 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009408 298.0
HFD2_k127_4921423_8 SpoIVB peptidase S55 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001712 286.0
HFD2_k127_4921423_9 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000003512 262.0
HFD2_k127_4947420_0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00311 - 1.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 592.0
HFD2_k127_4947420_1 Peptidase dimerisation domain K12941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 353.0
HFD2_k127_4947420_2 N-acyl-L-amino acid amidohydrolase K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 304.0
HFD2_k127_4947420_3 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003333 279.0
HFD2_k127_4947420_4 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000000000000000000004083 206.0
HFD2_k127_4947420_5 Peptidase dimerisation domain K01436 - - 0.000000000000000000000004797 105.0
HFD2_k127_4947420_6 Protein tyrosine kinase - - - 0.000007211 52.0
HFD2_k127_4996163_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 613.0
HFD2_k127_4996163_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004552 576.0
HFD2_k127_4996163_10 Cell division ATP-binding protein ftsE K09811,K09812 GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001193 268.0
HFD2_k127_4996163_11 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000005125 231.0
HFD2_k127_4996163_12 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000001553 229.0
HFD2_k127_4996163_13 aminopeptidase - - - 0.00000000000000000000000000000000000000000000000001228 206.0
HFD2_k127_4996163_14 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000006299 179.0
HFD2_k127_4996163_15 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000004165 149.0
HFD2_k127_4996163_16 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000003574 110.0
HFD2_k127_4996163_17 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000006154 89.0
HFD2_k127_4996163_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 569.0
HFD2_k127_4996163_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 492.0
HFD2_k127_4996163_4 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005372 473.0
HFD2_k127_4996163_5 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 485.0
HFD2_k127_4996163_6 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 486.0
HFD2_k127_4996163_7 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 456.0
HFD2_k127_4996163_8 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006923 401.0
HFD2_k127_4996163_9 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 354.0
HFD2_k127_511727_0 Tricorn protease homolog - - - 0.0 1057.0
HFD2_k127_511727_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 7.451e-276 872.0
HFD2_k127_511727_10 PFAM NADP oxidoreductase coenzyme F420-dependent K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 305.0
HFD2_k127_511727_11 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004557 291.0
HFD2_k127_511727_12 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006039 288.0
HFD2_k127_511727_13 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000001466 278.0
HFD2_k127_511727_14 response regulator, receiver K13069,K18967 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000046 271.0
HFD2_k127_511727_15 dolichyl monophosphate biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000001563 258.0
HFD2_k127_511727_16 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000003412 231.0
HFD2_k127_511727_17 Involved in the tonB-independent uptake of proteins K03641,K10117 - - 0.000000000000000000000000000000000000000000000000000000001313 233.0
HFD2_k127_511727_18 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000112 221.0
HFD2_k127_511727_19 SMART Integrin alpha beta-propellor repeat protein K01127 - 3.1.4.50 0.0000000000000000000000000000000000000000000000000000007226 224.0
HFD2_k127_511727_2 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 547.0
HFD2_k127_511727_20 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000000000000508 181.0
HFD2_k127_511727_21 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000009548 164.0
HFD2_k127_511727_22 Aspartyl protease - - - 0.000000000000000000000000000000000000003771 163.0
HFD2_k127_511727_23 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000007297 162.0
HFD2_k127_511727_24 Thrombospondin C-terminal region K04659 GO:0000902,GO:0001501,GO:0001503,GO:0001932,GO:0001934,GO:0001936,GO:0001938,GO:0001968,GO:0002020,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0002688,GO:0002690,GO:0003416,GO:0003417,GO:0003674,GO:0005102,GO:0005178,GO:0005198,GO:0005201,GO:0005488,GO:0005496,GO:0005499,GO:0005509,GO:0005515,GO:0005518,GO:0005539,GO:0005575,GO:0005576,GO:0005604,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005912,GO:0005924,GO:0005927,GO:0006928,GO:0006950,GO:0007155,GO:0007160,GO:0007275,GO:0007399,GO:0007517,GO:0007610,GO:0008150,GO:0008201,GO:0008284,GO:0008289,GO:0009653,GO:0009790,GO:0009887,GO:0009888,GO:0009893,GO:0009987,GO:0010562,GO:0010604,GO:0010941,GO:0012505,GO:0014812,GO:0016043,GO:0016203,GO:0016477,GO:0016525,GO:0016528,GO:0016529,GO:0019220,GO:0019222,GO:0019842,GO:0019899,GO:0021700,GO:0022008,GO:0022603,GO:0022607,GO:0022610,GO:0030030,GO:0030054,GO:0030055,GO:0030154,GO:0030182,GO:0030198,GO:0030334,GO:0030335,GO:0030855,GO:0031012,GO:0031175,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0031589,GO:0031594,GO:0032101,GO:0032103,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032879,GO:0032989,GO:0032990,GO:0032991,GO:0033554,GO:0033555,GO:0033627,GO:0034103,GO:0034976,GO:0035265,GO:0035989,GO:0036094,GO:0040007,GO:0040011,GO:0040012,GO:0040017,GO:0042127,GO:0042325,GO:0042327,GO:0042981,GO:0043062,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043236,GO:0043237,GO:0043394,GO:0043395,GO:0043931,GO:0043933,GO:0044085,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045202,GO:0045765,GO:0045937,GO:0046872,GO:0048265,GO:0048266,GO:0048468,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048589,GO:0048646,GO:0048666,GO:0048699,GO:0048705,GO:0048731,GO:0048736,GO:0048799,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050678,GO:0050679,GO:0050730,GO:0050731,GO:0050789,GO:0050793,GO:0050794,GO:0050839,GO:0050840,GO:0050896,GO:0050920,GO:0050921,GO:0051093,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051216,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0051270,GO:0051272,GO:0051451,GO:0051674,GO:0051716,GO:0060173,GO:0060231,GO:0060255,GO:0060343,GO:0060346,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060429,GO:0060538,GO:0060548,GO:0061053,GO:0061061,GO:0061383,GO:0061430,GO:0061448,GO:0062023,GO:0065003,GO:0065007,GO:0070161,GO:0070977,GO:0071603,GO:0071622,GO:0071624,GO:0071695,GO:0071840,GO:0080090,GO:0090022,GO:0090023,GO:0090136,GO:0097159,GO:0097367,GO:0098609,GO:0098868,GO:0120036,GO:0120039,GO:1901342,GO:1901343,GO:1901681,GO:1902622,GO:1902624,GO:2000026,GO:2000145,GO:2000147,GO:2000181 - 0.00000000000000000000000000000000000003261 162.0
HFD2_k127_511727_25 - - - - 0.00000000000000000000000000000000000004792 165.0
HFD2_k127_511727_26 PFAM Fibronectin, type III domain K01179,K06882 - 3.2.1.4 0.0000000000000000000000005576 124.0
HFD2_k127_511727_27 Two component transcriptional regulator, winged helix family K02483 - - 0.00000000000000000000006332 111.0
HFD2_k127_511727_29 Thrombospondin type 3 repeat - - - 0.0000000000003534 86.0
HFD2_k127_511727_3 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 536.0
HFD2_k127_511727_30 Thrombospondin type 3 repeat - - - 0.000000000003799 79.0
HFD2_k127_511727_31 Calcineurin-like phosphoesterase - - - 0.0000000004708 74.0
HFD2_k127_511727_32 Tetratricopeptide repeat - - - 0.000005214 60.0
HFD2_k127_511727_33 Putative MetA-pathway of phenol degradation - - - 0.00001851 55.0
HFD2_k127_511727_4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 550.0
HFD2_k127_511727_5 PFAM Glycosyl transferase family 2 K11936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 494.0
HFD2_k127_511727_6 Transporter, major facilitator family protein K08369 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 445.0
HFD2_k127_511727_7 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005334 405.0
HFD2_k127_511727_8 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 373.0
HFD2_k127_511727_9 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 361.0
HFD2_k127_5131602_0 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000919 444.0
HFD2_k127_5131602_1 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000001913 267.0
HFD2_k127_5131602_2 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000205 267.0
HFD2_k127_5131602_3 copG family - - - 0.0000000000000000000000000000000000000006874 153.0
HFD2_k127_5131602_4 methionine synthase - - - 0.00000000000000000001359 108.0
HFD2_k127_5131602_5 spore germination - - - 0.000000000008116 70.0
HFD2_k127_5186558_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 421.0
HFD2_k127_5186558_1 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 333.0
HFD2_k127_5186558_2 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000005235 227.0
HFD2_k127_5186558_3 PFAM nucleoside H symporter K05820 - - 0.00000000000000000000000000000000000000000000000000000004546 211.0
HFD2_k127_5186558_4 HELICc2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000006184 174.0
HFD2_k127_5186558_5 PFAM glycine cleavage T protein (aminomethyl transferase) K00605 - 2.1.2.10 0.00000000000000000000000000000000000001728 160.0
HFD2_k127_5186558_6 CbiX - - - 0.00000000000000000003288 105.0
HFD2_k127_5186558_7 Preprotein translocase SecG subunit K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000000000000004961 96.0
HFD2_k127_524574_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 8.427e-273 897.0
HFD2_k127_524574_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 2.233e-268 836.0
HFD2_k127_524574_2 cellulose binding - - - 2.919e-264 852.0
HFD2_k127_524574_3 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 625.0
HFD2_k127_524574_4 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003537 305.0
HFD2_k127_524574_5 SdpI/YhfL protein family - - - 0.000000000000000000000000000000000000000000000000000000000003782 218.0
HFD2_k127_524574_6 regulatory protein, arsR - - - 0.00000000000000000000000006134 110.0
HFD2_k127_5316015_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1320.0
HFD2_k127_5316015_1 Aromatic amino acid lyase K01745 - 4.3.1.3 4.502e-249 812.0
HFD2_k127_5316015_10 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 391.0
HFD2_k127_5316015_11 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 370.0
HFD2_k127_5316015_12 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 351.0
HFD2_k127_5316015_13 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568 318.0
HFD2_k127_5316015_14 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 317.0
HFD2_k127_5316015_15 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002517 278.0
HFD2_k127_5316015_16 Glutathione S-transferase, C-terminal domain K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005169 255.0
HFD2_k127_5316015_17 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000002132 255.0
HFD2_k127_5316015_18 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000005442 248.0
HFD2_k127_5316015_19 Protein of unknown function (DUF1348) K09958 - - 0.000000000000000000000000000000000000000000000000000000000000006885 219.0
HFD2_k127_5316015_2 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 1.275e-241 777.0
HFD2_k127_5316015_20 Uncharacterized protein conserved in bacteria (DUF2219) - - - 0.00000000000000000000000000000000000000000000000000001614 203.0
HFD2_k127_5316015_22 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000002231 190.0
HFD2_k127_5316015_23 - - - - 0.000000000000000000000000000000000000000003054 179.0
HFD2_k127_5316015_24 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.00000000000000000000000000000000000006012 154.0
HFD2_k127_5316015_25 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000001151 158.0
HFD2_k127_5316015_26 Transcriptional regulator - - - 0.000000000000000000000000000002201 125.0
HFD2_k127_5316015_27 hydrolase, family 25 - - - 0.00000000000000000000000003171 127.0
HFD2_k127_5316015_28 Domain of unknown function (DUF1956) - - - 0.00000000000000000002443 100.0
HFD2_k127_5316015_29 - - - - 0.00000000000000004319 95.0
HFD2_k127_5316015_3 Involved in the tonB-independent uptake of proteins - - - 4.812e-215 697.0
HFD2_k127_5316015_4 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009548 577.0
HFD2_k127_5316015_5 aldo keto reductase K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 544.0
HFD2_k127_5316015_6 Alcohol dehydrogenase GroES-like domain K13979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 492.0
HFD2_k127_5316015_7 COG2939 Carboxypeptidase C (cathepsin A) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 491.0
HFD2_k127_5316015_8 methyltransferase K20421 - 2.1.1.303 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 488.0
HFD2_k127_5316015_9 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 445.0
HFD2_k127_5321106_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006536 577.0
HFD2_k127_5321106_1 MatE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 482.0
HFD2_k127_5321106_2 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 411.0
HFD2_k127_5321106_3 Voltage gated chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 381.0
HFD2_k127_5321106_4 Domain of unknown function (DUF1731) K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 327.0
HFD2_k127_5321106_5 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.00000000000000000000000000000000000000008322 164.0
HFD2_k127_5321106_6 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000000000000000000000000000000001938 166.0
HFD2_k127_5321106_7 CoA binding domain K06929 - - 0.0000000000000000000000000000000000006548 143.0
HFD2_k127_5321106_8 Domain of unknown function (DUF4118) - - - 0.00002518 55.0
HFD2_k127_5329603_0 SMART Integrin alpha beta-propellor repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 342.0
HFD2_k127_5329603_1 ABC transporter K01990,K09697 - 3.6.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000006606 261.0
HFD2_k127_5329603_2 COG1668 ABC-type Na efflux pump, permease component K01992,K09696 - - 0.00000000000000000000000000000000000000000002112 186.0
HFD2_k127_5329603_3 Domain of unknown function DUF11 - - - 0.0000000000000000005071 102.0
HFD2_k127_5329603_4 ABC-2 family transporter protein K09696 - - 0.00007765 49.0
HFD2_k127_5362070_0 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000144 272.0
HFD2_k127_5362070_1 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000007396 203.0
HFD2_k127_5362070_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000366 159.0
HFD2_k127_5362070_3 PA14 domain - GO:0005575,GO:0005576 - 0.0000000000000000000000000000002192 143.0
HFD2_k127_5362070_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000008739 124.0
HFD2_k127_5362070_5 Biotin-requiring enzyme - - - 0.0000000000004076 77.0
HFD2_k127_5362070_6 oxidoreductase activity - - - 0.00000000002628 78.0
HFD2_k127_5397942_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 497.0
HFD2_k127_5397942_1 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 436.0
HFD2_k127_5397942_10 mannose-ethanolamine phosphotransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000007144 233.0
HFD2_k127_5397942_11 Amidinotransferase - - - 0.00000000000000000000000000000000000000000000000000002791 208.0
HFD2_k127_5397942_12 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000233 211.0
HFD2_k127_5397942_13 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000002672 185.0
HFD2_k127_5397942_14 PFAM glycosyl transferase family 39 K07264 - 2.4.2.43 0.00000000000000000000000000000000000000000000002382 192.0
HFD2_k127_5397942_15 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000007441 173.0
HFD2_k127_5397942_16 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000009008 154.0
HFD2_k127_5397942_17 Peptidase M56 - - - 0.000000000000000000000000000000000000003276 165.0
HFD2_k127_5397942_18 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000002863 139.0
HFD2_k127_5397942_2 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007947 400.0
HFD2_k127_5397942_20 PFAM Sporulation and spore germination - - - 0.0000000000001505 83.0
HFD2_k127_5397942_21 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000009745 81.0
HFD2_k127_5397942_3 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001413 286.0
HFD2_k127_5397942_4 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004989 287.0
HFD2_k127_5397942_5 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006598 273.0
HFD2_k127_5397942_6 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000007068 272.0
HFD2_k127_5397942_7 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000008251 259.0
HFD2_k127_5397942_8 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000007339 236.0
HFD2_k127_5397942_9 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000278 242.0
HFD2_k127_5500747_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1108.0
HFD2_k127_5500747_1 PFAM HhH-GPD superfamily base excision DNA repair protein K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000001462 192.0
HFD2_k127_5500747_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000001479 149.0
HFD2_k127_5500747_3 - - - - 0.0006536 51.0
HFD2_k127_5546935_0 Valyl tRNA synthetase tRNA binding arm K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 2.561e-310 975.0
HFD2_k127_5546935_1 Heat shock 70 kDa protein K04043 - - 2.414e-236 741.0
HFD2_k127_5546935_10 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005054 312.0
HFD2_k127_5546935_11 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007844 289.0
HFD2_k127_5546935_12 GTP binding K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000901 265.0
HFD2_k127_5546935_13 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000001721 248.0
HFD2_k127_5546935_14 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000001025 245.0
HFD2_k127_5546935_15 Competence protein ComEC K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000007366 252.0
HFD2_k127_5546935_16 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000001272 214.0
HFD2_k127_5546935_17 IstB-like ATP binding protein K02315 - - 0.0000000000000000000000000000000000000000000000000000006331 202.0
HFD2_k127_5546935_18 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000119 204.0
HFD2_k127_5546935_19 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000002582 199.0
HFD2_k127_5546935_2 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 6.197e-216 702.0
HFD2_k127_5546935_20 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000004401 167.0
HFD2_k127_5546935_21 helix_turn_helix, mercury resistance K13640 - - 0.00000000000000000000000000000000006146 139.0
HFD2_k127_5546935_22 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000002356 116.0
HFD2_k127_5546935_23 Hsp20/alpha crystallin family - - - 0.0000000000000000000000006507 111.0
HFD2_k127_5546935_24 outer membrane autotransporter barrel domain protein - - - 0.000000000000000002818 98.0
HFD2_k127_5546935_25 regulation of translation K05808,K05809 GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006446,GO:0006448,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000001204 90.0
HFD2_k127_5546935_26 lipopolysaccharide transport K09774 - - 0.0000000000000005093 92.0
HFD2_k127_5546935_27 Lipopolysaccharide-assembly, LptC-related - - - 0.000001005 62.0
HFD2_k127_5546935_3 PFAM Acyl-CoA dehydrogenase K00248,K22430 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 1.3.1.108,1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 449.0
HFD2_k127_5546935_4 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 411.0
HFD2_k127_5546935_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 402.0
HFD2_k127_5546935_6 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 347.0
HFD2_k127_5546935_7 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 356.0
HFD2_k127_5546935_8 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 329.0
HFD2_k127_5546935_9 PFAM ABC transporter related K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 316.0
HFD2_k127_5556825_0 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 412.0
HFD2_k127_5684397_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1335.0
HFD2_k127_5684397_1 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1039.0
HFD2_k127_5684397_10 - K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007939 251.0
HFD2_k127_5684397_11 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000003176 209.0
HFD2_k127_5684397_12 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000001454 159.0
HFD2_k127_5684397_13 lipopolysaccharide metabolic process K19804 - - 0.0000000000000000000000000000000000000001796 169.0
HFD2_k127_5684397_14 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000001639 133.0
HFD2_k127_5684397_15 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000001191 137.0
HFD2_k127_5684397_16 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000001634 131.0
HFD2_k127_5684397_17 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000000009166 115.0
HFD2_k127_5684397_18 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000002921 120.0
HFD2_k127_5684397_19 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - 0.000000000000000000000002026 117.0
HFD2_k127_5684397_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 531.0
HFD2_k127_5684397_20 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.000000000000000000000004297 114.0
HFD2_k127_5684397_21 Tetratricopeptide repeat - - - 0.000000000000000001661 100.0
HFD2_k127_5684397_22 Transcription factor zinc-finger K09981 - - 0.00000001172 63.0
HFD2_k127_5684397_23 Protein of unknown function, DUF481 K07283 - - 0.0000106 57.0
HFD2_k127_5684397_3 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 488.0
HFD2_k127_5684397_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 409.0
HFD2_k127_5684397_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 412.0
HFD2_k127_5684397_6 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008337 397.0
HFD2_k127_5684397_7 HlyD family secretion protein K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006684 328.0
HFD2_k127_5684397_8 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002517 286.0
HFD2_k127_5684397_9 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000819 276.0
HFD2_k127_5704839_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 603.0
HFD2_k127_571588_0 Dienelactone hydrolase family - - - 0.0 1145.0
HFD2_k127_571588_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006198 576.0
HFD2_k127_571588_10 Adenylylsulphate kinase K00860 - 2.7.1.25 0.000000000000000000000000000000000000000000000000000000000005269 216.0
HFD2_k127_571588_11 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000005552 197.0
HFD2_k127_571588_12 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0000000000000000000000000000000000000000000000003228 198.0
HFD2_k127_571588_13 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000000000001016 146.0
HFD2_k127_571588_14 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000003976 151.0
HFD2_k127_571588_15 capsule polysaccharide biosynthetic process - - - 0.0000000000000000000000000000001574 145.0
HFD2_k127_571588_16 Transglutaminase-like superfamily - - - 0.000000000000000000000000000004964 140.0
HFD2_k127_571588_17 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.00000000000000000000000000001509 137.0
HFD2_k127_571588_18 Metallo-peptidase family M12B Reprolysin-like - - - 0.000000000000000000000001334 118.0
HFD2_k127_571588_19 - - - - 0.000000000000000000001862 104.0
HFD2_k127_571588_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 541.0
HFD2_k127_571588_3 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 539.0
HFD2_k127_571588_4 Catalyzes the reversible hydration of fumarate to (S)- malate K01676,K03780 - 4.2.1.2,4.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 517.0
HFD2_k127_571588_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 516.0
HFD2_k127_571588_6 sulfate adenylyltransferase K00958 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 425.0
HFD2_k127_571588_7 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004339 273.0
HFD2_k127_571588_8 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000008726 235.0
HFD2_k127_571588_9 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000002169 224.0
HFD2_k127_5734391_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 1222.0
HFD2_k127_5734391_1 elongation factor Tu domain 2 protein K02355 - - 7.017e-245 775.0
HFD2_k127_5734391_10 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 411.0
HFD2_k127_5734391_11 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 421.0
HFD2_k127_5734391_12 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 411.0
HFD2_k127_5734391_13 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 404.0
HFD2_k127_5734391_14 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 396.0
HFD2_k127_5734391_15 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009267 404.0
HFD2_k127_5734391_16 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 412.0
HFD2_k127_5734391_17 ABC-type multidrug transport system ATPase and permease K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009356 390.0
HFD2_k127_5734391_18 Male sterility protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 367.0
HFD2_k127_5734391_19 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 367.0
HFD2_k127_5734391_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 550.0
HFD2_k127_5734391_20 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 345.0
HFD2_k127_5734391_21 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 338.0
HFD2_k127_5734391_22 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 344.0
HFD2_k127_5734391_23 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 339.0
HFD2_k127_5734391_24 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 319.0
HFD2_k127_5734391_25 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005672 330.0
HFD2_k127_5734391_26 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 306.0
HFD2_k127_5734391_27 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 285.0
HFD2_k127_5734391_28 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004017 272.0
HFD2_k127_5734391_29 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K04068,K10026 - 1.97.1.4,4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000002884 269.0
HFD2_k127_5734391_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 550.0
HFD2_k127_5734391_30 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004561 250.0
HFD2_k127_5734391_31 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002576 246.0
HFD2_k127_5734391_32 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000057 241.0
HFD2_k127_5734391_33 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000002127 257.0
HFD2_k127_5734391_34 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000006036 246.0
HFD2_k127_5734391_35 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000004005 243.0
HFD2_k127_5734391_36 TIGRFAM Mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000722 237.0
HFD2_k127_5734391_37 oxidoreductase K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000000000000000000000000000000000000000000000001079 247.0
HFD2_k127_5734391_38 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000001018 234.0
HFD2_k127_5734391_39 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000002146 222.0
HFD2_k127_5734391_4 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004891 556.0
HFD2_k127_5734391_40 Aminotransferase K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000001798 226.0
HFD2_k127_5734391_41 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000004796 226.0
HFD2_k127_5734391_42 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000007894 201.0
HFD2_k127_5734391_43 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000014 202.0
HFD2_k127_5734391_45 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000001389 194.0
HFD2_k127_5734391_46 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000247 189.0
HFD2_k127_5734391_47 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000006116 190.0
HFD2_k127_5734391_48 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000001272 188.0
HFD2_k127_5734391_49 3-demethylubiquinone-9 3-O-methyltransferase activity K15257 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000001901 193.0
HFD2_k127_5734391_5 ABC transporter transmembrane region K06147,K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 544.0
HFD2_k127_5734391_50 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000002943 183.0
HFD2_k127_5734391_51 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000007284 186.0
HFD2_k127_5734391_52 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000000000000000000000000000000000000000008171 181.0
HFD2_k127_5734391_53 'dna polymerase iii K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000001615 176.0
HFD2_k127_5734391_54 - - - - 0.0000000000000000000000000000000000000000001195 173.0
HFD2_k127_5734391_55 Group 1 family - - - 0.00000000000000000000000000000000000000000121 176.0
HFD2_k127_5734391_56 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.000000000000000000000000000000000000000001422 177.0
HFD2_k127_5734391_57 O-Antigen ligase - - - 0.0000000000000000000000000000000000000009818 170.0
HFD2_k127_5734391_58 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity K12583 GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000003081 154.0
HFD2_k127_5734391_59 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.0000000000000000000000000000000000259 149.0
HFD2_k127_5734391_6 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007268 494.0
HFD2_k127_5734391_60 Polysaccharide deacetylase - - - 0.0000000000000000000000000000004129 132.0
HFD2_k127_5734391_61 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000005888 126.0
HFD2_k127_5734391_62 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000009971 123.0
HFD2_k127_5734391_63 Polysaccharide deacetylase - - - 0.0000000000000000000000002458 123.0
HFD2_k127_5734391_64 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000237 116.0
HFD2_k127_5734391_65 enzyme binding K00567,K07443 - 2.1.1.63 0.000000000000000000000006132 108.0
HFD2_k127_5734391_66 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000001531 107.0
HFD2_k127_5734391_67 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000002181 113.0
HFD2_k127_5734391_68 Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway K16148 - 2.4.1.342 0.0000000000000000001523 102.0
HFD2_k127_5734391_69 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000005028 93.0
HFD2_k127_5734391_7 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 471.0
HFD2_k127_5734391_70 Acetyltransferase (GNAT) domain - - - 0.000000000000003018 89.0
HFD2_k127_5734391_71 methyltransferase K15471 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016741,GO:0022607,GO:0032259,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071770,GO:0071840,GO:0071944 - 0.000000000000006234 85.0
HFD2_k127_5734391_72 O-Antigen ligase K18814 - - 0.00000000003847 76.0
HFD2_k127_5734391_73 40-residue YVTN family beta-propeller repeat - - - 0.00000000009571 76.0
HFD2_k127_5734391_74 polysaccharide deacetylase - - - 0.0000000005107 72.0
HFD2_k127_5734391_75 Peptidase M48 - - - 0.000000003652 69.0
HFD2_k127_5734391_76 protein conserved in bacteria K09778 - - 0.0000001109 62.0
HFD2_k127_5734391_78 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.00002735 50.0
HFD2_k127_5734391_79 Aldehyde dehydrogenase K14519 - 1.2.1.4 0.0002345 49.0
HFD2_k127_5734391_8 PFAM Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 471.0
HFD2_k127_5734391_9 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 468.0
HFD2_k127_5780122_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 7.874e-245 785.0
HFD2_k127_5780122_1 Peptidase family S58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 480.0
HFD2_k127_5780122_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 447.0
HFD2_k127_5780122_3 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 306.0
HFD2_k127_5780122_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000001367 200.0
HFD2_k127_5800760_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 396.0
HFD2_k127_5800760_1 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000009272 211.0
HFD2_k127_5800760_2 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000002969 189.0
HFD2_k127_5800760_3 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000002586 196.0
HFD2_k127_5800760_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000005483 174.0
HFD2_k127_5800760_5 Short-chain dehydrogenase reductase SDR K03793 - 1.5.1.33 0.00000000000000000000000000000000000006829 160.0
HFD2_k127_5800760_6 amine dehydrogenase activity - - - 0.000000000000000000000000000003467 137.0
HFD2_k127_5814958_0 Peptidase family M1 domain - - - 0.0 1089.0
HFD2_k127_5814958_1 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 449.0
HFD2_k127_5814958_2 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 396.0
HFD2_k127_5814958_3 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 332.0
HFD2_k127_5814958_4 proline dipeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000001467 234.0
HFD2_k127_5814958_5 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.00000000000000000000000000000000000000000000001664 193.0
HFD2_k127_5814958_6 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.0000000000000000000000000000000000000007548 152.0
HFD2_k127_5814958_7 Amidohydrolase family - - - 0.000000000000000000000001545 119.0
HFD2_k127_5814958_8 TonB C terminal K03832 - - 0.00000000000000000001222 106.0
HFD2_k127_5814958_9 Patatin-like phospholipase - - - 0.00000000000000000001557 97.0
HFD2_k127_5840485_0 DEAD/H associated K03724 - - 0.0 1343.0
HFD2_k127_5840485_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 319.0
HFD2_k127_5840485_2 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000303 251.0
HFD2_k127_5840485_3 Allophanate hydrolase subunit 1 K06351 - - 0.0000000000000000000000000000000000000000000000000000000000005162 223.0
HFD2_k127_5840485_4 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000001709 194.0
HFD2_k127_5840485_5 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.000000000000000000000000005796 112.0
HFD2_k127_5840485_6 Allophanate hydrolase subunit 2 - - - 0.00000000000001148 86.0
HFD2_k127_5840485_7 - - - - 0.00006457 55.0
HFD2_k127_5842782_0 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 554.0
HFD2_k127_5842782_1 ABC-2 family transporter protein K01992,K07052,K09696 - - 0.000000000000000000000000000000000000000000003478 182.0
HFD2_k127_5842782_2 - - - - 0.000000000000000000183 102.0
HFD2_k127_5844224_0 Phosphoglucose isomerase K01810 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.3.1.9 1.629e-275 855.0
HFD2_k127_5844224_1 Amylo-alpha-1,6-glucosidase - - - 8.407e-233 741.0
HFD2_k127_5844224_10 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 365.0
HFD2_k127_5844224_11 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 377.0
HFD2_k127_5844224_12 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 368.0
HFD2_k127_5844224_13 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 321.0
HFD2_k127_5844224_14 fructose 1,6-bisphosphate 1-phosphatase activity K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000005912 284.0
HFD2_k127_5844224_15 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000007163 231.0
HFD2_k127_5844224_16 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000002899 214.0
HFD2_k127_5844224_17 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000198 203.0
HFD2_k127_5844224_18 - - - - 0.00002517 58.0
HFD2_k127_5844224_2 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 1.209e-210 679.0
HFD2_k127_5844224_3 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 588.0
HFD2_k127_5844224_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 567.0
HFD2_k127_5844224_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 521.0
HFD2_k127_5844224_6 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 485.0
HFD2_k127_5844224_7 lyase activity K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 486.0
HFD2_k127_5844224_8 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 452.0
HFD2_k127_5844224_9 Glycosyl hydrolase family 57 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 407.0
HFD2_k127_5852740_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.582e-249 784.0
HFD2_k127_5852740_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 4.962e-209 676.0
HFD2_k127_5852740_10 acetyltransferases and hydrolases with the alpha beta hydrolase fold K07002 - - 0.00000000000000000000000000000000000000000000000000000007744 211.0
HFD2_k127_5852740_11 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000002059 201.0
HFD2_k127_5852740_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02022,K16922,K20345 - - 0.000000000000000000000000000000000000000000000000000002468 218.0
HFD2_k127_5852740_13 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000003549 202.0
HFD2_k127_5852740_14 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000003814 209.0
HFD2_k127_5852740_15 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000002525 192.0
HFD2_k127_5852740_16 methyltransferase - - - 0.000000000000000000000000000000000000000000003675 185.0
HFD2_k127_5852740_17 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000001873 180.0
HFD2_k127_5852740_18 glycosyl transferase family 2 K20444 - - 0.00000000000000000000000000003965 135.0
HFD2_k127_5852740_19 lyase activity - - - 0.0000000000000000001167 98.0
HFD2_k127_5852740_2 Acyl transferase domain - - - 3.738e-201 666.0
HFD2_k127_5852740_20 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.00000000000000009474 96.0
HFD2_k127_5852740_21 Putative metal-binding motif - - - 0.00000000000001121 90.0
HFD2_k127_5852740_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 463.0
HFD2_k127_5852740_4 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 412.0
HFD2_k127_5852740_6 Esterase PHB depolymerase K03932 - - 0.000000000000000000000000000000000000000000000000000000000001456 222.0
HFD2_k127_5852740_7 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000001625 220.0
HFD2_k127_5852740_8 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000003321 208.0
HFD2_k127_5852740_9 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000003912 225.0
HFD2_k127_5865909_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1134.0
HFD2_k127_5865909_1 TIGRFAM leucyl-tRNA synthetase K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 5.832e-281 888.0
HFD2_k127_5865909_10 NUBPL iron-transfer P-loop NTPase K16554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 358.0
HFD2_k127_5865909_11 Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 334.0
HFD2_k127_5865909_12 Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006027 282.0
HFD2_k127_5865909_13 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003678 286.0
HFD2_k127_5865909_14 O-Antigen ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006939 280.0
HFD2_k127_5865909_15 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000002146 254.0
HFD2_k127_5865909_16 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000003998 251.0
HFD2_k127_5865909_17 LmbE homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000004277 240.0
HFD2_k127_5865909_18 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000006082 212.0
HFD2_k127_5865909_19 Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55) K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000001149 213.0
HFD2_k127_5865909_2 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 3.374e-217 692.0
HFD2_k127_5865909_20 WbqC-like protein family - - - 0.0000000000000000000000000000000000000000000000000002406 197.0
HFD2_k127_5865909_21 Glycosyl transferases group 1 K13668 GO:0000009,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0033164,GO:0040007,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.346 0.0000000000000000000000000000000000000000000000006548 199.0
HFD2_k127_5865909_22 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000214 171.0
HFD2_k127_5865909_23 Protein conserved in bacteria K06320 - - 0.000000000000000000000000000000000000000000003067 185.0
HFD2_k127_5865909_24 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000002358 181.0
HFD2_k127_5865909_25 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000009825 180.0
HFD2_k127_5865909_26 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000649 175.0
HFD2_k127_5865909_27 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000002192 162.0
HFD2_k127_5865909_28 COG0859 ADP-heptose LPS heptosyltransferase K02841,K02849 - - 0.00000000000000000000000000000000000004208 164.0
HFD2_k127_5865909_29 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000004274 151.0
HFD2_k127_5865909_3 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.283e-200 644.0
HFD2_k127_5865909_30 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.0000000000000000000000000000000004391 140.0
HFD2_k127_5865909_31 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000002397 138.0
HFD2_k127_5865909_32 glycogen (starch) synthase activity - - - 0.0000000000000000000000000000005053 136.0
HFD2_k127_5865909_33 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000001343 133.0
HFD2_k127_5865909_34 - - - - 0.000000000000000000000000002336 124.0
HFD2_k127_5865909_35 Lipopolysaccharide-assembly - - - 0.0000000000000000000000008886 111.0
HFD2_k127_5865909_36 phosphorelay signal transduction system - - - 0.0000000000000000000008313 110.0
HFD2_k127_5865909_37 regulator, PATAN and FRGAF domain-containing - - - 0.000000000000000000006202 101.0
HFD2_k127_5865909_38 Polysaccharide biosynthesis/export protein - - - 0.0000000000000000001621 104.0
HFD2_k127_5865909_39 Polysaccharide biosynthesis C-terminal domain - - - 0.0000000000000001277 95.0
HFD2_k127_5865909_4 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 604.0
HFD2_k127_5865909_40 Uncharacterised nucleotidyltransferase - - - 0.00000000001128 77.0
HFD2_k127_5865909_41 DNA-directed DNA polymerase activity K02340 - 2.7.7.7 0.00000000004099 74.0
HFD2_k127_5865909_42 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.0000000003502 74.0
HFD2_k127_5865909_43 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000005258 60.0
HFD2_k127_5865909_45 E-Z type HEAT repeats - - - 0.000384 52.0
HFD2_k127_5865909_5 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 538.0
HFD2_k127_5865909_6 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 424.0
HFD2_k127_5865909_7 COG0367 Asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 403.0
HFD2_k127_5865909_8 Uncharacterized protein family UPF0004 K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 397.0
HFD2_k127_5865909_9 Permease YjgP YjgQ family protein K07091,K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 387.0
HFD2_k127_5866467_0 DNA topological change - - - 4.087e-218 709.0
HFD2_k127_5866467_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 504.0
HFD2_k127_5866467_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000827 281.0
HFD2_k127_5866467_3 - - - - 0.0000000000000000000000000000000006266 149.0
HFD2_k127_5866467_4 Protein of unknown function (DUF1569) - - - 0.000000000000000000000000000000002336 134.0
HFD2_k127_5866467_5 PKD domain containing protein - - - 0.00000000000000000000000004165 124.0
HFD2_k127_5866467_6 PA domain - - - 0.0000000000009605 81.0
HFD2_k127_5866467_7 YjbR - - - 0.000000000002663 79.0
HFD2_k127_5866467_8 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00004342 47.0
HFD2_k127_5876033_0 Malic enzyme, NAD binding domain K00027,K00029,K00625,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 7.912e-309 967.0
HFD2_k127_5876033_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 2.378e-266 836.0
HFD2_k127_5876033_10 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000002192 179.0
HFD2_k127_5876033_11 COG1136 ABC-type antimicrobial peptide transport system, ATPase component K02003,K09810 - - 0.0000000000000000000000000000000000000001533 158.0
HFD2_k127_5876033_12 YCII-related domain K09780 - - 0.0000000000000000000000000000000004826 140.0
HFD2_k127_5876033_13 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.0000000000000000000000882 103.0
HFD2_k127_5876033_14 - - - - 0.00000000000000000001553 100.0
HFD2_k127_5876033_15 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000001019 79.0
HFD2_k127_5876033_16 Regulatory protein, FmdB family - - - 0.000000000003761 74.0
HFD2_k127_5876033_17 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. - - - 0.00000768 53.0
HFD2_k127_5876033_2 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 564.0
HFD2_k127_5876033_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175,K00177,K00187 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 513.0
HFD2_k127_5876033_4 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008045 449.0
HFD2_k127_5876033_5 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008585 448.0
HFD2_k127_5876033_6 alanine dehydrogenase activity K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 338.0
HFD2_k127_5876033_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 323.0
HFD2_k127_5876033_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006896 321.0
HFD2_k127_5876033_9 Glutamine amidotransferase class-I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 295.0
HFD2_k127_5935823_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001068 265.0
HFD2_k127_5935823_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000001722 239.0
HFD2_k127_5935823_2 PFAM Single-stranded nucleic acid binding R3H K06346 - - 0.000000000000000000007085 99.0
HFD2_k127_5935823_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000416 97.0
HFD2_k127_5935823_4 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000001828 80.0
HFD2_k127_5935823_5 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000009319 66.0
HFD2_k127_5936621_0 AcrB/AcrD/AcrF family K07787,K15726 - - 0.0 1315.0
HFD2_k127_5936621_1 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009447 623.0
HFD2_k127_5936621_10 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003499 303.0
HFD2_k127_5936621_11 aspartate racemase K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006619 277.0
HFD2_k127_5936621_12 PFAM Outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000264 290.0
HFD2_k127_5936621_13 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000001728 242.0
HFD2_k127_5936621_14 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000000000000000000000000000000001516 207.0
HFD2_k127_5936621_15 ferredoxin-NADP+ reductase activity - - - 0.00000000000000000000000000000000000009559 156.0
HFD2_k127_5936621_16 - - - - 0.0000000000000000000000004759 121.0
HFD2_k127_5936621_17 Protein of unknown function (DUF454) K09790 - - 0.00000000000000776 87.0
HFD2_k127_5936621_18 Cupin superfamily (DUF985) K09705 - - 0.0000000003688 70.0
HFD2_k127_5936621_19 Belongs to the glycosyl hydrolase 18 family - - - 0.0000008612 61.0
HFD2_k127_5936621_2 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 546.0
HFD2_k127_5936621_3 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 524.0
HFD2_k127_5936621_4 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007574 492.0
HFD2_k127_5936621_5 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007981 438.0
HFD2_k127_5936621_6 beta-lactamase domain protein K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 395.0
HFD2_k127_5936621_7 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 391.0
HFD2_k127_5936621_8 methyltransferase activity K21310 - 2.1.1.334 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 322.0
HFD2_k127_5936621_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 307.0
HFD2_k127_5944112_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 6.766e-221 732.0
HFD2_k127_5944112_1 PFAM isocitrate isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008877 532.0
HFD2_k127_5944112_10 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000247 275.0
HFD2_k127_5944112_11 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003777 287.0
HFD2_k127_5944112_12 Transglycosylase K05366,K21464 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001017 294.0
HFD2_k127_5944112_13 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000006958 278.0
HFD2_k127_5944112_14 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003214 276.0
HFD2_k127_5944112_15 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001792 267.0
HFD2_k127_5944112_16 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003174 263.0
HFD2_k127_5944112_17 transferase activity, transferring glycosyl groups K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000003415 255.0
HFD2_k127_5944112_18 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000001036 237.0
HFD2_k127_5944112_19 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000007964 235.0
HFD2_k127_5944112_2 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009647 535.0
HFD2_k127_5944112_20 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000006481 218.0
HFD2_k127_5944112_21 Lecithin:cholesterol acyltransferase - - - 0.000000000000000000000000000000000000000000000000000005099 209.0
HFD2_k127_5944112_22 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000008725 194.0
HFD2_k127_5944112_23 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000001226 208.0
HFD2_k127_5944112_24 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000006321 187.0
HFD2_k127_5944112_25 Protein involved in cellulose biosynthesis - - - 0.00000000000000000000000000000000000000000000000005958 194.0
HFD2_k127_5944112_26 Protein of unknown function (DUF1698) - - - 0.000000000000000000000000000000000000000000000005596 189.0
HFD2_k127_5944112_27 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000008258 198.0
HFD2_k127_5944112_28 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000002229 172.0
HFD2_k127_5944112_29 B12 binding domain - - - 0.000000000000000000000000000000000000004241 165.0
HFD2_k127_5944112_3 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 509.0
HFD2_k127_5944112_30 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000006205 161.0
HFD2_k127_5944112_31 Lipopolysaccharide biosynthesis protein - - - 0.0000000000000000000000000000002863 139.0
HFD2_k127_5944112_32 Capsular exopolysaccharide family K08252 - 2.7.10.1 0.000000000000000000000000000001971 140.0
HFD2_k127_5944112_33 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000196 131.0
HFD2_k127_5944112_34 OmpA family - - - 0.0000000000000000000000003856 118.0
HFD2_k127_5944112_35 Transcription termination factor nusG K05785 - - 0.000000000000000000002029 102.0
HFD2_k127_5944112_36 Phospholipid methyltransferase - - - 0.00000000000000000003594 97.0
HFD2_k127_5944112_37 - - - - 0.0000000000000000001949 93.0
HFD2_k127_5944112_38 Periplasmic or secreted lipoprotein - - - 0.00000000000000004075 91.0
HFD2_k127_5944112_39 - - - - 0.00000000000003256 73.0
HFD2_k127_5944112_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 476.0
HFD2_k127_5944112_40 Putative beta-barrel porin 2 - - - 0.0000000007108 72.0
HFD2_k127_5944112_41 COG3307 Lipid A core - O-antigen ligase and related enzymes - - - 0.00000003684 67.0
HFD2_k127_5944112_42 Acid phosphatase homologues - - - 0.0000001741 64.0
HFD2_k127_5944112_5 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 479.0
HFD2_k127_5944112_6 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 419.0
HFD2_k127_5944112_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 419.0
HFD2_k127_5944112_8 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 370.0
HFD2_k127_5944112_9 Heparinase II/III N-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008206 335.0
HFD2_k127_6011095_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1155.0
HFD2_k127_6011095_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 629.0
HFD2_k127_6011095_2 NUBPL iron-transfer P-loop NTPase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 306.0
HFD2_k127_6011095_3 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000004007 241.0
HFD2_k127_6011095_4 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000008993 100.0
HFD2_k127_6011095_5 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000001307 101.0
HFD2_k127_6011095_6 Polymer-forming cytoskeletal - - - 0.00000000000000000001377 101.0
HFD2_k127_6011095_7 Ca2 -binding protein (EF-Hand superfamily - - - 0.0002548 53.0
HFD2_k127_601189_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009696 584.0
HFD2_k127_601189_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 560.0
HFD2_k127_601189_10 Dystroglycan-type cadherin-like domains. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 351.0
HFD2_k127_601189_11 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 352.0
HFD2_k127_601189_12 Conserved hypothetical ATP binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 316.0
HFD2_k127_601189_13 3-oxoacid CoA-transferase, B subunit K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004653 271.0
HFD2_k127_601189_14 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000002241 239.0
HFD2_k127_601189_15 Oxygen tolerance - - - 0.0000000000000000000000000000000000000000000000000000000001061 234.0
HFD2_k127_601189_16 O-linked GlcNAc transferase-putative TPR-containing transmembrane protein - - - 0.0000000000000000000000000000000000000000000000000000000004477 229.0
HFD2_k127_601189_17 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000356 203.0
HFD2_k127_601189_18 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000002406 190.0
HFD2_k127_601189_19 arylsulfatase A - - - 0.00000000000000000000000000000000000000000000000008337 199.0
HFD2_k127_601189_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 476.0
HFD2_k127_601189_20 radical SAM domain protein K22227 - - 0.00000000000000000000000000000000000000000000001854 184.0
HFD2_k127_601189_21 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000002355 183.0
HFD2_k127_601189_22 Thrombospondin type 3 repeat - - - 0.0000000000000000000000000000000000000000000133 183.0
HFD2_k127_601189_23 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000003548 183.0
HFD2_k127_601189_24 diguanylate cyclase - - - 0.000000000000000000000000000000000000005473 167.0
HFD2_k127_601189_25 Peptidase family C25 - - - 0.00000000000000000000000000000000000008469 166.0
HFD2_k127_601189_26 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000001229 147.0
HFD2_k127_601189_27 belongs to the thioredoxin family K03671,K03672 - 1.8.1.8 0.0000000000000000000000000000000000002161 143.0
HFD2_k127_601189_28 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000006147 143.0
HFD2_k127_601189_29 subunit of a heme lyase K02198,K02200,K04016,K04017,K04018 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564 - 0.0000000000000000000000001023 123.0
HFD2_k127_601189_3 ATPase associated with various cellular K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 463.0
HFD2_k127_601189_30 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000001091 112.0
HFD2_k127_601189_31 Tetratricopeptide repeat - - - 0.00000000000000000000006359 116.0
HFD2_k127_601189_32 Sigma-70, region 4 K03088 - - 0.00000000000000000007281 101.0
HFD2_k127_601189_33 regulator, PATAN and FRGAF domain-containing - - - 0.000000000000000005285 94.0
HFD2_k127_601189_35 - - - - 0.00000000000908 76.0
HFD2_k127_601189_36 - - - - 0.00000000001004 76.0
HFD2_k127_601189_37 PA14 domain - - - 0.00000000002181 79.0
HFD2_k127_601189_39 Putative zinc-finger - - - 0.0002519 53.0
HFD2_k127_601189_4 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 372.0
HFD2_k127_601189_40 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000683 47.0
HFD2_k127_601189_5 Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008609 365.0
HFD2_k127_601189_6 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 357.0
HFD2_k127_601189_7 3-oxoacid CoA-transferase, a subunit K01027,K01028,K01031,K01034 - 2.8.3.5,2.8.3.6,2.8.3.8,2.8.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 333.0
HFD2_k127_601189_8 PFAM PfkB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 334.0
HFD2_k127_601189_9 von Willebrand factor (vWF) type A domain K07114,K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 353.0
HFD2_k127_603472_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702,K08999 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 1.985e-286 894.0
HFD2_k127_603472_1 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 3.182e-199 633.0
HFD2_k127_603472_10 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000005809 153.0
HFD2_k127_603472_11 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000541 157.0
HFD2_k127_603472_12 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000001648 150.0
HFD2_k127_603472_13 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000006124 79.0
HFD2_k127_603472_14 Belongs to the UPF0109 family K06960 - - 0.00000000000004212 76.0
HFD2_k127_603472_15 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000005593 74.0
HFD2_k127_603472_16 Methyltransferase - - - 0.00000000001459 77.0
HFD2_k127_603472_17 Alpha beta superfamily - - - 0.000000003285 68.0
HFD2_k127_603472_18 - - - - 0.000000005189 67.0
HFD2_k127_603472_2 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 613.0
HFD2_k127_603472_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 541.0
HFD2_k127_603472_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 497.0
HFD2_k127_603472_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 446.0
HFD2_k127_603472_6 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004501 280.0
HFD2_k127_603472_7 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000000003599 231.0
HFD2_k127_603472_8 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000002206 198.0
HFD2_k127_603472_9 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000004847 201.0
HFD2_k127_6096891_0 Heat shock 70 kDa protein K04043 - - 1.866e-279 872.0
HFD2_k127_6096891_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 408.0
HFD2_k127_6096891_10 Domain of unknown function (DUF1844) - - - 0.000000001998 65.0
HFD2_k127_6096891_11 peptidyl-tyrosine sulfation - - - 0.0001695 55.0
HFD2_k127_6096891_2 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004196 406.0
HFD2_k127_6096891_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007218 377.0
HFD2_k127_6096891_4 Tyrosine recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 304.0
HFD2_k127_6096891_5 MazG nucleotide pyrophosphohydrolase domain K04765 - 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000001106 251.0
HFD2_k127_6096891_6 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000003627 208.0
HFD2_k127_6096891_7 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000001718 166.0
HFD2_k127_6096891_8 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000008776 156.0
HFD2_k127_6096891_9 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000002251 70.0
HFD2_k127_610035_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.822e-283 897.0
HFD2_k127_610035_1 Heat shock 70 kDa protein K04043 - - 5.166e-229 725.0
HFD2_k127_610035_10 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003539 281.0
HFD2_k127_610035_11 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000002554 218.0
HFD2_k127_610035_12 PFAM MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000007042 164.0
HFD2_k127_610035_13 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000003892 170.0
HFD2_k127_610035_14 diguanylate cyclase - - - 0.0000000000000000000000000000000000000004037 167.0
HFD2_k127_610035_15 PFAM OmpA MotB domain protein K03640 - - 0.0000000000000000000000000000000000008297 148.0
HFD2_k127_610035_16 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000001965 128.0
HFD2_k127_610035_17 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.00000000000000000000000000000007862 131.0
HFD2_k127_610035_18 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000004941 125.0
HFD2_k127_610035_19 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000009533 97.0
HFD2_k127_610035_2 Peptidase dimerisation domain - - - 2.599e-200 667.0
HFD2_k127_610035_20 Acid phosphatase homologues - - - 0.000000000000003329 90.0
HFD2_k127_610035_21 Binds directly to 16S ribosomal RNA K02968 - - 0.000000005778 65.0
HFD2_k127_610035_22 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 0.0000001632 64.0
HFD2_k127_610035_23 Sporulation related domain - - - 0.0000008112 62.0
HFD2_k127_610035_24 energy transducer activity K03832 - - 0.00001415 57.0
HFD2_k127_610035_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009467 391.0
HFD2_k127_610035_4 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 339.0
HFD2_k127_610035_5 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 343.0
HFD2_k127_610035_6 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 344.0
HFD2_k127_610035_7 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 334.0
HFD2_k127_610035_8 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 302.0
HFD2_k127_610035_9 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006753 285.0
HFD2_k127_6127647_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.0 1121.0
HFD2_k127_6127647_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 1.923e-226 707.0
HFD2_k127_6127647_10 TIGRFAM amino acid carrier protein K03310 - - 0.00000000000000000000000000000000000307 141.0
HFD2_k127_6127647_11 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000002519 146.0
HFD2_k127_6127647_12 lyase activity - - - 0.000000204 62.0
HFD2_k127_6127647_2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 635.0
HFD2_k127_6127647_3 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 622.0
HFD2_k127_6127647_4 metallophosphoesterase K07096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007689 325.0
HFD2_k127_6127647_5 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 319.0
HFD2_k127_6127647_6 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000003751 222.0
HFD2_k127_6127647_7 collagen metabolic process K08677 - - 0.0000000000000000000000000000000000000000000000000000004676 223.0
HFD2_k127_6127647_8 chitinase - - - 0.000000000000000000000000000000000000000000000000001665 204.0
HFD2_k127_6127647_9 - - - - 0.000000000000000000000000000000000000000000001266 170.0
HFD2_k127_6142900_0 PFAM Glycosyl transferase family 2 - - - 6.783e-314 984.0
HFD2_k127_6142900_1 PFAM Aminotransferase class I and II K00814 - 2.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005406 449.0
HFD2_k127_6142900_2 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 432.0
HFD2_k127_6142900_3 Bacterial virulence protein (VirJ) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004274 235.0
HFD2_k127_6142900_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000006801 231.0
HFD2_k127_6142900_5 ABC transporter K02003 - - 0.00000000000000000000002494 102.0
HFD2_k127_6142900_6 Transglutaminase-like superfamily - - - 0.00000000000000001993 95.0
HFD2_k127_6185680_0 extracellular matrix structural constituent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004197 279.0
HFD2_k127_6185680_1 alpha/beta hydrolase fold - - - 0.0000000004898 73.0
HFD2_k127_6233728_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 581.0
HFD2_k127_6233728_1 Bacterial regulatory protein, Fis family K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 297.0
HFD2_k127_6238241_0 Sortilin, neurotensin receptor 3, - - - 0.0 1191.0
HFD2_k127_6238241_1 Sulfatase K01130 - 3.1.6.1 1.163e-296 919.0
HFD2_k127_6238241_10 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000001782 72.0
HFD2_k127_6238241_11 - - - - 0.0000003305 65.0
HFD2_k127_6238241_12 Sortilin, neurotensin receptor 3, - - - 0.000002263 62.0
HFD2_k127_6238241_2 PFAM Na dependent nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 338.0
HFD2_k127_6238241_3 3-demethylubiquinone-9 3-O-methyltransferase activity K16328 - 2.7.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 301.0
HFD2_k127_6238241_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000004006 211.0
HFD2_k127_6238241_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000001003 149.0
HFD2_k127_6238241_6 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.0000000000000000000000000000000002829 144.0
HFD2_k127_6238241_7 Transmembrane and TPR repeat-containing protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0008150,GO:0012505,GO:0016020,GO:0031984,GO:0042175,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0048878,GO:0050801,GO:0055065,GO:0055074,GO:0055080,GO:0065007,GO:0065008,GO:0072507,GO:0098771,GO:0098827 - 0.000000000000000000053 105.0
HFD2_k127_6238241_8 chlorophyll binding - - - 0.00000000002192 79.0
HFD2_k127_6238241_9 - - - - 0.0000000001456 70.0
HFD2_k127_6265564_0 rRNA (guanine-N2-)-methyltransferase activity K13604,K21460 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0036067,GO:0036069,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.304,2.1.1.333 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 543.0
HFD2_k127_6265564_1 PFAM Iron permease FTR1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 310.0
HFD2_k127_6265564_10 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000002883 58.0
HFD2_k127_6265564_11 MacB-like periplasmic core domain K02004 - - 0.0006424 50.0
HFD2_k127_6265564_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 296.0
HFD2_k127_6265564_3 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000007124 218.0
HFD2_k127_6265564_4 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000005306 188.0
HFD2_k127_6265564_5 Belongs to the Fur family K03711 - - 0.000000000000000000000000000003056 126.0
HFD2_k127_6265564_6 Thioredoxin - - - 0.000000000000000000000000002649 121.0
HFD2_k127_6265564_7 Methyltransferase - - - 0.00000000000000000000000004352 119.0
HFD2_k127_6265564_8 Cupin domain - - - 0.00000000000000000002204 104.0
HFD2_k127_6265564_9 TonB-dependent receptor - - - 0.000000000000005001 89.0
HFD2_k127_6270490_0 Participates in initiation and elongation during chromosome replication K02314,K02316 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000007223 229.0
HFD2_k127_6270490_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.00000000000000000000000000000000001534 139.0
HFD2_k127_6271329_0 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 452.0
HFD2_k127_6271329_1 PFAM Thiamine pyrophosphate enzyme, C-terminal K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 328.0
HFD2_k127_6271329_2 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000677 207.0
HFD2_k127_6271329_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.0000000000000666 77.0
HFD2_k127_6277669_0 Acetyl-coenzyme A transporter 1 K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 606.0
HFD2_k127_6277669_1 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 553.0
HFD2_k127_6277669_10 PFAM Major Facilitator Superfamily - - - 0.000000000000000000002373 109.0
HFD2_k127_6277669_11 PFAM DSBA oxidoreductase - - - 0.0005125 49.0
HFD2_k127_6277669_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008681 472.0
HFD2_k127_6277669_3 signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 452.0
HFD2_k127_6277669_4 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 400.0
HFD2_k127_6277669_5 Electron transfer flavoprotein K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000003578 246.0
HFD2_k127_6277669_6 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000009537 204.0
HFD2_k127_6277669_7 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000002892 211.0
HFD2_k127_6277669_8 Thioredoxin - - - 0.000000000000000000000000000000000000000000628 162.0
HFD2_k127_6277669_9 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000001785 121.0
HFD2_k127_631183_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 454.0
HFD2_k127_631183_1 electron transfer activity K00428 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 404.0
HFD2_k127_631183_2 protoporphyrinogen oxidase activity K01854,K21779 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249,GO:0055114 5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000403 230.0
HFD2_k127_631183_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000008318 126.0
HFD2_k127_631183_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000006403 72.0
HFD2_k127_63644_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 609.0
HFD2_k127_63644_1 Aminotransferase class-V K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 497.0
HFD2_k127_63644_10 Arginase family K01476 - 3.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 345.0
HFD2_k127_63644_11 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 304.0
HFD2_k127_63644_12 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 298.0
HFD2_k127_63644_13 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002562 299.0
HFD2_k127_63644_14 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006097 274.0
HFD2_k127_63644_15 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002776 286.0
HFD2_k127_63644_16 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000005564 259.0
HFD2_k127_63644_17 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002764 256.0
HFD2_k127_63644_18 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003019 256.0
HFD2_k127_63644_19 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000004223 222.0
HFD2_k127_63644_2 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 474.0
HFD2_k127_63644_20 Male sterility protein K15891 - 1.1.1.354 0.00000000000000000000000000000000000000000000000000000000000001848 238.0
HFD2_k127_63644_21 PFAM EAL domain - - - 0.000000000000000000000000000000000000000000000000000000000001721 228.0
HFD2_k127_63644_22 3-hydroxyanthranilic acid dioxygenase K00452 - 1.13.11.6 0.000000000000000000000000000000000000000000000000000000000007623 212.0
HFD2_k127_63644_23 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000007706 216.0
HFD2_k127_63644_24 PSP1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000001806 207.0
HFD2_k127_63644_25 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000008951 199.0
HFD2_k127_63644_26 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000007178 213.0
HFD2_k127_63644_27 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000025 181.0
HFD2_k127_63644_28 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000006443 170.0
HFD2_k127_63644_29 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576 1.1.1.133 0.00000000000000000000000000000000000000000002366 186.0
HFD2_k127_63644_3 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 462.0
HFD2_k127_63644_30 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000526 169.0
HFD2_k127_63644_31 Organic solvent tolerance protein K04744 - - 0.000000000000000000000000000000000000000001963 181.0
HFD2_k127_63644_32 PFAM Integral membrane protein DUF92 - GO:0005575,GO:0016020 - 0.0000000000000000000000000000000008232 147.0
HFD2_k127_63644_33 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000172 138.0
HFD2_k127_63644_34 - - - - 0.000000000000000000000000000000602 140.0
HFD2_k127_63644_35 TPM domain K06872 - - 0.000000000000000000000000000003246 136.0
HFD2_k127_63644_36 Putative metal-binding motif - - - 0.00000000000000000000000004046 127.0
HFD2_k127_63644_37 Tetratricopeptide repeat - - - 0.0000000000000000000000377 117.0
HFD2_k127_63644_38 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00000000000002039 87.0
HFD2_k127_63644_39 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K05970 - 3.1.1.53 0.000000000003887 81.0
HFD2_k127_63644_4 FAD binding domain K00486 - 1.14.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 416.0
HFD2_k127_63644_40 Thiamine biosynthesis K03154 - - 0.000000000006939 76.0
HFD2_k127_63644_41 STAS domain K04749 - - 0.0000000003312 67.0
HFD2_k127_63644_42 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.000000001073 65.0
HFD2_k127_63644_43 Methyltransferase TYW3 - - - 0.000000008587 70.0
HFD2_k127_63644_44 Transposase - - - 0.0000001226 54.0
HFD2_k127_63644_45 Phosphoserine phosphatase - - - 0.000001221 61.0
HFD2_k127_63644_46 PFAM Transposase DDE domain - - - 0.0004293 46.0
HFD2_k127_63644_5 Tryptophan 2,3-dioxygenase K00453 - 1.13.11.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 361.0
HFD2_k127_63644_6 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 365.0
HFD2_k127_63644_7 thiamine diphosphate biosynthetic process K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 353.0
HFD2_k127_63644_8 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007802 343.0
HFD2_k127_63644_9 regulation of canonical Wnt signaling pathway involved in osteoblast differentiation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008094 351.0
HFD2_k127_6372198_0 4Fe-4S dicluster domain K00184 - - 5.942e-300 955.0
HFD2_k127_6372198_1 glutamine synthetase K01915 - 6.3.1.2 4.027e-231 724.0
HFD2_k127_6372198_10 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 352.0
HFD2_k127_6372198_11 Aminotransferase class-V K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009352 328.0
HFD2_k127_6372198_12 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 310.0
HFD2_k127_6372198_13 Cytochrome c7 and related cytochrome c K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 302.0
HFD2_k127_6372198_14 ornithine cyclodeaminase K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001828 280.0
HFD2_k127_6372198_15 lipoprotein localization to outer membrane K02004,K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002033 280.0
HFD2_k127_6372198_16 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001112 277.0
HFD2_k127_6372198_17 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001462 267.0
HFD2_k127_6372198_18 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000003296 239.0
HFD2_k127_6372198_19 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000001393 237.0
HFD2_k127_6372198_2 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 590.0
HFD2_k127_6372198_20 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000003574 243.0
HFD2_k127_6372198_21 Belongs to the beta-ketoacyl-ACP synthases family K05551,K09458 - 2.3.1.179,2.3.1.235,2.3.1.260 0.000000000000000000000000000000000000000000000000000000001255 220.0
HFD2_k127_6372198_22 Roadblock/LC7 domain - - - 0.00000000000000000000000000000000000000000000000000002501 193.0
HFD2_k127_6372198_23 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000000000000000000000000000000000000000000000006326 194.0
HFD2_k127_6372198_24 Cytochrome c - - - 0.0000000000000000000000000000000000000000002796 177.0
HFD2_k127_6372198_25 protein tyrosine kinase activity K03593 - - 0.000000000000000000000000000000000000000008824 167.0
HFD2_k127_6372198_26 Cytochrome c - - - 0.00000000000000000000000000000000000000001529 176.0
HFD2_k127_6372198_27 glycosyl transferase - - - 0.0000000000000000000000000000000000000001562 161.0
HFD2_k127_6372198_28 - - - - 0.0000000000000000000000000000000000000001737 162.0
HFD2_k127_6372198_29 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.00000000000000000000000000000000000007348 156.0
HFD2_k127_6372198_3 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 578.0
HFD2_k127_6372198_30 sigma factor activity K02405 - - 0.0000000000000000000000000000000000007298 151.0
HFD2_k127_6372198_31 Histidine kinase - - - 0.000000000000000000000000000000000009983 154.0
HFD2_k127_6372198_32 Methyltransferase domain - - - 0.00000000000000000000000000001799 133.0
HFD2_k127_6372198_33 CHAT domain - - - 0.00000000000000000000000001963 128.0
HFD2_k127_6372198_34 proteolysis - - - 0.00000000000000000416 98.0
HFD2_k127_6372198_35 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000000001676 82.0
HFD2_k127_6372198_36 Proto-chlorophyllide reductase 57 kd subunit - - - 0.00000000000005178 85.0
HFD2_k127_6372198_37 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000008083 81.0
HFD2_k127_6372198_38 protein SCO1 SenC K07152 - - 0.0000000003318 69.0
HFD2_k127_6372198_39 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000001142 65.0
HFD2_k127_6372198_4 Rubrerythrin K22405 - 1.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007844 501.0
HFD2_k127_6372198_40 - - - - 0.000001799 55.0
HFD2_k127_6372198_41 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000008843 59.0
HFD2_k127_6372198_42 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.00005579 57.0
HFD2_k127_6372198_43 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0008566 51.0
HFD2_k127_6372198_5 Protein of unknown function (DUF692) K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 420.0
HFD2_k127_6372198_6 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007776 381.0
HFD2_k127_6372198_7 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 377.0
HFD2_k127_6372198_8 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 372.0
HFD2_k127_6372198_9 Proto-chlorophyllide reductase 57 kD subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 367.0
HFD2_k127_6394588_0 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000006039 243.0
HFD2_k127_6394588_1 proteolysis K03665 - - 0.000001591 61.0
HFD2_k127_6415262_0 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009677 499.0
HFD2_k127_6415262_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 473.0
HFD2_k127_6511775_0 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000007718 139.0
HFD2_k127_6511775_1 SMART metal-dependent phosphohydrolase, HD K07037 - - 0.0000000005605 72.0
HFD2_k127_6531221_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 428.0
HFD2_k127_6531221_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 320.0
HFD2_k127_6531221_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.00000000000000000000000000000000000000000000000000000001744 211.0
HFD2_k127_6585319_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 5.476e-265 859.0
HFD2_k127_6585319_1 Carbohydrate phosphorylase K00688 - 2.4.1.1 5.322e-238 756.0
HFD2_k127_6585319_10 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001594 277.0
HFD2_k127_6585319_11 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009042 275.0
HFD2_k127_6585319_12 response regulator K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000005334 247.0
HFD2_k127_6585319_13 metal-dependent phosphohydrolase, HD sub domain K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000004764 233.0
HFD2_k127_6585319_14 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000143 224.0
HFD2_k127_6585319_15 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000001476 213.0
HFD2_k127_6585319_16 Hexapeptide repeat of succinyl-transferase K13018 - 2.3.1.201 0.000000000000000000000000000000000000000000000000000006631 206.0
HFD2_k127_6585319_17 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000002441 197.0
HFD2_k127_6585319_18 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000034 151.0
HFD2_k127_6585319_19 Glycosyltransferase family 87 - - - 0.000000000000000000000000000000000006144 160.0
HFD2_k127_6585319_2 Domain of unknown function (DUF3473) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 501.0
HFD2_k127_6585319_20 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.0000000000000000000000000007368 130.0
HFD2_k127_6585319_21 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000000002936 113.0
HFD2_k127_6585319_22 Glycosyltransferase family 87 - - - 0.000000000000000000009551 109.0
HFD2_k127_6585319_23 Glutamate carboxypeptidase 2 K01301 GO:0000003,GO:0003002,GO:0003006,GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005575,GO:0006508,GO:0006807,GO:0007275,GO:0007389,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009314,GO:0009416,GO:0009628,GO:0009639,GO:0009640,GO:0009653,GO:0009790,GO:0009791,GO:0009793,GO:0009888,GO:0009908,GO:0009909,GO:0010015,GO:0010051,GO:0010073,GO:0010074,GO:0010075,GO:0010080,GO:0010081,GO:0010082,GO:0010154,GO:0010305,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0019827,GO:0022414,GO:0022622,GO:0031224,GO:0032501,GO:0032502,GO:0040008,GO:0043170,GO:0044238,GO:0044425,GO:0048316,GO:0048364,GO:0048367,GO:0048507,GO:0048509,GO:0048580,GO:0048608,GO:0048638,GO:0048731,GO:0048831,GO:0048856,GO:0050789,GO:0050793,GO:0050896,GO:0051239,GO:0061458,GO:0065007,GO:0070011,GO:0071704,GO:0080050,GO:0090567,GO:0098727,GO:0099402,GO:0140096,GO:1901564,GO:1905392,GO:2000026,GO:2000034,GO:2000241,GO:2000280 3.4.17.21 0.000000000000000007615 92.0
HFD2_k127_6585319_24 PFAM Methyltransferase type 11 - - - 0.000000000002764 76.0
HFD2_k127_6585319_25 Dolichyl-phosphate-mannose-protein mannosyltransferase K14340 - - 0.00000000003128 76.0
HFD2_k127_6585319_27 CHAD - - - 0.00000001579 65.0
HFD2_k127_6585319_28 Cyclophilin-like K09143 - - 0.000004057 58.0
HFD2_k127_6585319_3 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 472.0
HFD2_k127_6585319_4 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 471.0
HFD2_k127_6585319_5 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 424.0
HFD2_k127_6585319_6 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 357.0
HFD2_k127_6585319_7 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 361.0
HFD2_k127_6585319_8 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 331.0
HFD2_k127_6585319_9 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 329.0
HFD2_k127_6591444_0 DNA polymerase alpha chain like domain K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 473.0
HFD2_k127_6591444_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000001056 205.0
HFD2_k127_6722940_0 aconitate hydratase K01681 - 4.2.1.3 1.2e-317 1009.0
HFD2_k127_6722940_1 Flavin containing amine oxidoreductase - - - 1.541e-274 852.0
HFD2_k127_6722940_10 DNA-templated transcription, initiation K03088,K03091 - - 0.000000000000000000000000003898 121.0
HFD2_k127_6722940_11 oxidoreductase activity - - - 0.00001449 58.0
HFD2_k127_6722940_12 Domain of unknown function (DUF4880) K07165 - - 0.0001757 54.0
HFD2_k127_6722940_2 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00135,K00138,K00146 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.39,1.2.1.79,1.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 587.0
HFD2_k127_6722940_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009023 512.0
HFD2_k127_6722940_4 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006554 485.0
HFD2_k127_6722940_5 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 349.0
HFD2_k127_6722940_6 PFAM Chlorite dismutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001133 297.0
HFD2_k127_6722940_7 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000003906 189.0
HFD2_k127_6722940_8 Polysaccharide lyase family 4, domain II - - - 0.00000000000000000000000000000000000000000002931 174.0
HFD2_k127_6722940_9 DoxX-like family K15977 - - 0.0000000000000000000000000000001223 139.0
HFD2_k127_6796748_0 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 636.0
HFD2_k127_6796748_1 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 633.0
HFD2_k127_6796748_10 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000001781 243.0
HFD2_k127_6796748_11 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000004585 176.0
HFD2_k127_6796748_12 peptidyl-tyrosine sulfation K01277 - 3.4.14.4 0.000000000000000000000002909 118.0
HFD2_k127_6796748_13 transposition, DNA-mediated K02342 - 2.7.7.7 0.000000000000000001167 98.0
HFD2_k127_6796748_14 Putative metal-binding motif - - - 0.0000003625 64.0
HFD2_k127_6796748_15 Protein of unknown function (DUF1579) - - - 0.000001665 54.0
HFD2_k127_6796748_16 oligopeptide transporter, OPT family - - - 0.00006212 48.0
HFD2_k127_6796748_2 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 610.0
HFD2_k127_6796748_3 oligopeptide transporter, OPT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 587.0
HFD2_k127_6796748_4 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 530.0
HFD2_k127_6796748_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 505.0
HFD2_k127_6796748_6 MFP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 465.0
HFD2_k127_6796748_7 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 362.0
HFD2_k127_6796748_8 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 339.0
HFD2_k127_6796748_9 Amino acid permease K20265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006964 331.0
HFD2_k127_6850265_0 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000007335 119.0
HFD2_k127_6850265_1 IMG reference gene - - - 0.00000000000000001875 93.0
HFD2_k127_6864585_0 Berberine and berberine like - - - 9.598e-228 718.0
HFD2_k127_6864585_1 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007552 618.0
HFD2_k127_6864585_10 - - - - 0.0000754 52.0
HFD2_k127_6864585_2 all-trans-retinol 13,14-reductase activity K00316 - 1.5.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008769 496.0
HFD2_k127_6864585_3 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 473.0
HFD2_k127_6864585_4 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003327 269.0
HFD2_k127_6864585_5 Belongs to the peptidase S8 family K01400,K01417,K20274 - 3.4.24.28 0.0000000000000000000000000000000000000000000000006554 202.0
HFD2_k127_6864585_6 - - - - 0.000000000000000000000000000000000000000000003963 175.0
HFD2_k127_6864585_7 protein conserved in bacteria K09984 - - 0.00000000000000000000000000000002241 128.0
HFD2_k127_6864585_8 Lanthionine synthetase C family protein - - - 0.000000000000000000000000000001884 130.0
HFD2_k127_6864585_9 Tetratricopeptide repeat - - - 0.0000000005906 72.0
HFD2_k127_6880386_0 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000003814 182.0
HFD2_k127_6880386_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000002942 140.0
HFD2_k127_6880386_2 ABC transporter K01990,K09695 - - 0.0000000000000000001778 88.0
HFD2_k127_6885934_0 Peptidase family M1 domain - - - 0.0 1101.0
HFD2_k127_6885934_1 ABC-type multidrug transport system ATPase component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 406.0
HFD2_k127_6885934_10 PFAM peptidase M24 - - - 0.00000000000000000000000000000000000000000000000000000000001995 222.0
HFD2_k127_6885934_11 protein conserved in bacteria K09797 - - 0.0000000000000000000000000000000000000000000000000000000001034 218.0
HFD2_k127_6885934_12 SdpI/YhfL protein family - - - 0.000000000000000000000000000000000000000000000000000008384 200.0
HFD2_k127_6885934_13 Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000000000000000002617 172.0
HFD2_k127_6885934_14 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000002514 181.0
HFD2_k127_6885934_15 - - - - 0.000000000000000000000000000000000000000001652 160.0
HFD2_k127_6885934_16 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.00000000000000000000000000000000000000004039 157.0
HFD2_k127_6885934_17 PFAM glycosyl transferase family 39 K14340 - - 0.000000000000000000000000000000000000001185 167.0
HFD2_k127_6885934_18 - - - - 0.000000000000000000000000000000000000003843 155.0
HFD2_k127_6885934_19 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000002341 139.0
HFD2_k127_6885934_2 Putative Na+/H+ antiporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 430.0
HFD2_k127_6885934_20 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000000000000002958 141.0
HFD2_k127_6885934_21 Psort location CytoplasmicMembrane, score - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000006098 124.0
HFD2_k127_6885934_22 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000003507 121.0
HFD2_k127_6885934_23 Tetratricopeptide repeat - - - 0.000000000000000000000000000216 130.0
HFD2_k127_6885934_25 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000002434 109.0
HFD2_k127_6885934_26 peptidase M48, Ste24p - - - 0.0000000000000000000002213 112.0
HFD2_k127_6885934_27 TonB C terminal K03832 - - 0.0000000000000000004026 103.0
HFD2_k127_6885934_28 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000001708 94.0
HFD2_k127_6885934_29 - - - - 0.0000000000000004752 91.0
HFD2_k127_6885934_3 Extradiol ring-cleavage dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008528 345.0
HFD2_k127_6885934_30 PFAM Redoxin domain protein - - - 0.000007772 53.0
HFD2_k127_6885934_31 YacP-like NYN domain K06962 - - 0.00008423 55.0
HFD2_k127_6885934_4 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 340.0
HFD2_k127_6885934_5 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.00000000000000000000000000000000000000000000000000000000000000000000000001113 272.0
HFD2_k127_6885934_6 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003852 247.0
HFD2_k127_6885934_7 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000005107 226.0
HFD2_k127_6885934_8 Histidine kinase K02482,K03557 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000007588 234.0
HFD2_k127_6885934_9 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000000000000000001474 213.0
HFD2_k127_6946712_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 3.536e-291 953.0
HFD2_k127_6946712_1 L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 621.0
HFD2_k127_6946712_10 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000001331 188.0
HFD2_k127_6946712_11 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000001615 201.0
HFD2_k127_6946712_12 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000004845 189.0
HFD2_k127_6946712_13 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000001547 151.0
HFD2_k127_6946712_14 repeat-containing protein - - - 0.0000000000000000000000000000000006284 151.0
HFD2_k127_6946712_15 Involved in DNA repair and RecF pathway recombination K03474,K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 0.000000000000000000000000000000002415 139.0
HFD2_k127_6946712_16 Could be involved in septation K06412 - - 0.00000000000000000000000000002832 120.0
HFD2_k127_6946712_17 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000002872 102.0
HFD2_k127_6946712_18 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000007757 108.0
HFD2_k127_6946712_19 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000298 96.0
HFD2_k127_6946712_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 498.0
HFD2_k127_6946712_21 - - - - 0.000000000003185 73.0
HFD2_k127_6946712_22 COG1520 FOG WD40-like repeat K17713 - - 0.00000001456 67.0
HFD2_k127_6946712_23 PFAM glutaredoxin 2 - - - 0.000003085 57.0
HFD2_k127_6946712_3 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 426.0
HFD2_k127_6946712_4 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008661 422.0
HFD2_k127_6946712_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 400.0
HFD2_k127_6946712_6 Dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000773 396.0
HFD2_k127_6946712_7 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 364.0
HFD2_k127_6946712_8 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 302.0
HFD2_k127_6946712_9 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000007564 257.0
HFD2_k127_6984842_0 PFAM Type II secretion system protein E K02454,K02504,K02652 - - 8.494e-254 795.0
HFD2_k127_6984842_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 8.656e-250 792.0
HFD2_k127_6984842_10 phosphorelay signal transduction system K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 475.0
HFD2_k127_6984842_11 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005854 471.0
HFD2_k127_6984842_12 Endoribonuclease that initiates mRNA decay K18682 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008153 447.0
HFD2_k127_6984842_13 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 443.0
HFD2_k127_6984842_14 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 419.0
HFD2_k127_6984842_15 ribonuclease Rne Rng family K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 407.0
HFD2_k127_6984842_16 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 372.0
HFD2_k127_6984842_17 - K12065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 358.0
HFD2_k127_6984842_18 Secretin and TonB N terminus short domain K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 369.0
HFD2_k127_6984842_19 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 370.0
HFD2_k127_6984842_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.572e-206 662.0
HFD2_k127_6984842_20 pilus assembly protein K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009863 341.0
HFD2_k127_6984842_21 chorismate binding enzyme K01657,K01665 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 336.0
HFD2_k127_6984842_22 histidine kinase A domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 340.0
HFD2_k127_6984842_23 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 319.0
HFD2_k127_6984842_24 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 313.0
HFD2_k127_6984842_25 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 294.0
HFD2_k127_6984842_26 reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001174 284.0
HFD2_k127_6984842_27 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000004271 270.0
HFD2_k127_6984842_28 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003464 271.0
HFD2_k127_6984842_29 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000002523 253.0
HFD2_k127_6984842_3 TIGRFAM glycerol-3-phosphate dehydrogenase, anaerobic, C subunit K00113 - 1.1.5.3 4.406e-201 668.0
HFD2_k127_6984842_30 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000002818 234.0
HFD2_k127_6984842_31 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000002182 244.0
HFD2_k127_6984842_32 (Rhomboid) family K07059 - - 0.000000000000000000000000000000000000000000000000000000000005212 218.0
HFD2_k127_6984842_33 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000007496 216.0
HFD2_k127_6984842_34 GHMP kinases N terminal domain K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000009114 219.0
HFD2_k127_6984842_35 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000006821 221.0
HFD2_k127_6984842_36 DHH family K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000001459 217.0
HFD2_k127_6984842_37 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000000002037 211.0
HFD2_k127_6984842_38 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000002389 206.0
HFD2_k127_6984842_39 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000318 207.0
HFD2_k127_6984842_4 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 612.0
HFD2_k127_6984842_40 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000002653 201.0
HFD2_k127_6984842_41 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000008009 180.0
HFD2_k127_6984842_42 Homocysteine S-methyltransferase - - - 0.0000000000000000000000000000000000000000000001048 179.0
HFD2_k127_6984842_43 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.000000000000000000000000000000000000000001971 175.0
HFD2_k127_6984842_44 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000005817 160.0
HFD2_k127_6984842_45 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000001158 165.0
HFD2_k127_6984842_46 dephospho-CoA kinase activity - - - 0.00000000000000000000000000000000001417 147.0
HFD2_k127_6984842_47 Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate - - - 0.00000000000000000000000000000000001681 143.0
HFD2_k127_6984842_48 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000000002142 153.0
HFD2_k127_6984842_49 MoaE protein K21142 - 2.8.1.12 0.0000000000000000000000000000000002918 136.0
HFD2_k127_6984842_5 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 572.0
HFD2_k127_6984842_50 integral membrane protein - - - 0.000000000000000000000000000000000569 148.0
HFD2_k127_6984842_51 Cell shape-determining protein MreC K03570 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963 - 0.0000000000000000000000000000000006671 142.0
HFD2_k127_6984842_52 methylenetetrahydrofolate reductase (NAD(P)H) activity K00297 - 1.5.1.20 0.00000000000000000000000000000002536 138.0
HFD2_k127_6984842_53 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000004345 134.0
HFD2_k127_6984842_54 Thioesterase superfamily - - - 0.00000000000000000000000000000007122 144.0
HFD2_k127_6984842_55 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000001041 137.0
HFD2_k127_6984842_56 FMN_bind - - - 0.0000000000000000000000000004402 130.0
HFD2_k127_6984842_57 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000001545 119.0
HFD2_k127_6984842_58 FecR protein - - - 0.00000000000000000000001337 115.0
HFD2_k127_6984842_59 Sigma-70, region 4 K03088 - - 0.0000000000000000000003629 113.0
HFD2_k127_6984842_6 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 532.0
HFD2_k127_6984842_60 oligosaccharyl transferase activity - - - 0.0000000000000000000008568 111.0
HFD2_k127_6984842_61 - - - - 0.00000000000000000001239 101.0
HFD2_k127_6984842_62 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.00000000000000000002468 94.0
HFD2_k127_6984842_63 Pilus assembly protein, PilO K02664 - - 0.0000000000000000004091 94.0
HFD2_k127_6984842_64 Ribosomal L28 family K02902 - - 0.000000000000000002124 87.0
HFD2_k127_6984842_65 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.00000000000000003167 97.0
HFD2_k127_6984842_66 Polymer-forming cytoskeletal - - - 0.000000000001197 74.0
HFD2_k127_6984842_68 chlorophyll binding - - - 0.000000000005917 80.0
HFD2_k127_6984842_69 membrane K11622 - - 0.00000000001332 75.0
HFD2_k127_6984842_7 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009985 494.0
HFD2_k127_6984842_70 PFAM Fimbrial assembly family protein K02663 - - 0.0000000005008 70.0
HFD2_k127_6984842_71 Tetratricopeptide repeat - - - 0.000000006541 66.0
HFD2_k127_6984842_72 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K21142 - 2.8.1.12 0.00000003757 65.0
HFD2_k127_6984842_73 - - - - 0.00000007897 64.0
HFD2_k127_6984842_74 Transmembrane and TPR repeat-containing protein 4 - - - 0.0000001211 64.0
HFD2_k127_6984842_75 - - - - 0.0000002097 65.0
HFD2_k127_6984842_76 peptidyl-tyrosine sulfation - - - 0.00000138 62.0
HFD2_k127_6984842_78 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity K03429 - 2.4.1.315 0.000004586 58.0
HFD2_k127_6984842_8 MreB/Mbl protein K03569 GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005886,GO:0007049,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0032505,GO:0042802,GO:0043093,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051782,GO:0051983,GO:0065007,GO:0065008,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 478.0
HFD2_k127_6984842_80 Tetratricopeptide repeat - - - 0.0007393 51.0
HFD2_k127_6984842_9 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006441 464.0
HFD2_k127_7049896_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 550.0
HFD2_k127_7049896_1 Protein of unknown function (DUF1016) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 491.0
HFD2_k127_7049896_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 307.0
HFD2_k127_7049896_3 PFAM glycosyl transferase group 1 K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005006 288.0
HFD2_k127_7049896_4 PFAM GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000002148 124.0
HFD2_k127_7049896_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000001439 64.0
HFD2_k127_7074402_0 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000001631 124.0
HFD2_k127_7074402_1 Polysaccharide biosynthesis protein - - - 0.000000000000000000003901 109.0
HFD2_k127_7074402_2 Glycosyl transferases group 1 - - - 0.0000000000000000008381 102.0
HFD2_k127_7074402_3 Methyltransferase domain - - - 0.00001037 59.0
HFD2_k127_7125063_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02474,K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009304 515.0
HFD2_k127_7125063_1 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 499.0
HFD2_k127_7125063_2 Domain of unknown function (DUF4143) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 418.0
HFD2_k127_7125063_3 Pfam:DUF2029 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 415.0
HFD2_k127_7125063_4 Pyridoxal-phosphate dependent enzyme K01751 - 4.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000002818 276.0
HFD2_k127_7125063_5 -acetyltransferase - - - 0.00000000000000000000000000000000000000000000000885 185.0
HFD2_k127_7125063_6 Bacterial membrane protein YfhO - - - 0.000000000000000000000000001021 132.0
HFD2_k127_7168766_0 Cys/Met metabolism PLP-dependent enzyme K01739,K01761 - 2.5.1.48,4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 520.0
HFD2_k127_7168766_1 ASPIC and UnbV - - - 0.00000000000000000408 94.0
HFD2_k127_7191622_0 Surface antigen K07277,K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008138 368.0
HFD2_k127_7191622_1 calcium, potassium:sodium antiporter activity K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 329.0
HFD2_k127_7191622_2 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000004526 169.0
HFD2_k127_7191622_3 PDZ domain (Also known as DHR or GLGF) K03797 - 3.4.21.102 0.000000000000000001508 100.0
HFD2_k127_7209725_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 374.0
HFD2_k127_7209725_1 serine-type endopeptidase activity K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 309.0
HFD2_k127_7209725_10 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000008629 98.0
HFD2_k127_7209725_11 Periplasmic or secreted lipoprotein - - - 0.00000000000003331 80.0
HFD2_k127_7209725_2 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 296.0
HFD2_k127_7209725_3 Protein export membrane protein K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001211 299.0
HFD2_k127_7209725_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002187 269.0
HFD2_k127_7209725_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006961 276.0
HFD2_k127_7209725_6 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000103 175.0
HFD2_k127_7209725_7 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000002598 127.0
HFD2_k127_7209725_8 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.000000000000000000000001164 111.0
HFD2_k127_7209725_9 cell redox homeostasis K02199,K03671 - - 0.0000000000000000000002375 108.0
HFD2_k127_7266803_0 Domain of unknown function (DUF1998) K02336,K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.7.7.7 3.365e-292 944.0
HFD2_k127_7266803_1 Sulfate permease family - - - 3.944e-275 859.0
HFD2_k127_7266803_10 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008623 464.0
HFD2_k127_7266803_11 COG NOG10142 non supervised orthologous group - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 465.0
HFD2_k127_7266803_12 Belongs to the glutaminase family K01425 - 3.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 449.0
HFD2_k127_7266803_13 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 471.0
HFD2_k127_7266803_14 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 452.0
HFD2_k127_7266803_15 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 424.0
HFD2_k127_7266803_16 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 400.0
HFD2_k127_7266803_17 Belongs to the asparaginase 1 family K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 387.0
HFD2_k127_7266803_18 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 352.0
HFD2_k127_7266803_19 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006757 319.0
HFD2_k127_7266803_2 Predicted Permease Membrane Region - - - 2.721e-207 658.0
HFD2_k127_7266803_20 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 312.0
HFD2_k127_7266803_21 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 306.0
HFD2_k127_7266803_22 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000075 252.0
HFD2_k127_7266803_23 Deoxynucleoside kinase K15518 - 2.7.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000005001 254.0
HFD2_k127_7266803_24 PFAM regulatory protein LuxR K13041 - - 0.00000000000000000000000000000000000000000000000000000000001555 216.0
HFD2_k127_7266803_25 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane K09476 - - 0.00000000000000000000000000000000000000000003264 181.0
HFD2_k127_7266803_26 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000001431 158.0
HFD2_k127_7266803_27 CoaE-domain-containing protein K00859 GO:0000166,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005739,GO:0005783,GO:0005811,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0012505,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990143 2.7.1.24 0.000000000000000000000000000000002092 147.0
HFD2_k127_7266803_28 Pfam Response regulator receiver - - - 0.0000000000000000000000002799 109.0
HFD2_k127_7266803_29 Belongs to the bacterial histone-like protein family K03530 - - 0.00000000000000000000007509 104.0
HFD2_k127_7266803_3 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 3.806e-207 664.0
HFD2_k127_7266803_30 Virulence factor BrkB K07058 - - 0.0000000000000000001982 98.0
HFD2_k127_7266803_31 Tetratricopeptide repeat - - - 0.0000000000001741 79.0
HFD2_k127_7266803_32 Protein of unknown function (DUF3011) - - - 0.000000001935 71.0
HFD2_k127_7266803_33 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000175 63.0
HFD2_k127_7266803_4 Fumarase C C-terminus K01744 - 4.3.1.1 2.1e-201 655.0
HFD2_k127_7266803_5 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 521.0
HFD2_k127_7266803_6 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009014 511.0
HFD2_k127_7266803_7 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009709 505.0
HFD2_k127_7266803_8 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 481.0
HFD2_k127_7266803_9 Inorganic ion transport and metabolism K03319 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 484.0
HFD2_k127_7294666_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 2.918e-198 629.0
HFD2_k127_7294666_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 371.0
HFD2_k127_7294666_10 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000001472 246.0
HFD2_k127_7294666_11 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000000003536 225.0
HFD2_k127_7294666_12 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000009747 243.0
HFD2_k127_7294666_13 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000008383 223.0
HFD2_k127_7294666_14 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000001028 228.0
HFD2_k127_7294666_15 FES K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000007908 205.0
HFD2_k127_7294666_16 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000473 201.0
HFD2_k127_7294666_17 Hydantoinase/oxoprolinase K07072 - 2.5.1.131 0.00000000000000000000000000000000000000000000000000000006881 209.0
HFD2_k127_7294666_18 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000001235 182.0
HFD2_k127_7294666_19 CarD-like/TRCF domain K07736 - - 0.00000000000000000000000000000000000004214 149.0
HFD2_k127_7294666_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 333.0
HFD2_k127_7294666_20 Domain of unknown function (DUF814) - - - 0.00000000000000000000000000000000000009421 160.0
HFD2_k127_7294666_21 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000002738 163.0
HFD2_k127_7294666_22 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000000000002699 154.0
HFD2_k127_7294666_23 acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.000000000000000000000000000644 128.0
HFD2_k127_7294666_24 FecR protein - - - 0.000000000000000000000000004683 127.0
HFD2_k127_7294666_25 Lipid A Biosynthesis N-terminal domain - - - 0.00000000000000000000000003736 110.0
HFD2_k127_7294666_26 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.000000000000000000000006925 113.0
HFD2_k127_7294666_27 Pfam ATP-grasp domain K06914 - 6.3.4.24 0.00000000000000000000001437 113.0
HFD2_k127_7294666_28 - - - - 0.00000000000000000000003975 111.0
HFD2_k127_7294666_29 Histidine biosynthesis protein K01814 - 5.3.1.16 0.000000000000000000005242 108.0
HFD2_k127_7294666_3 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000001015 273.0
HFD2_k127_7294666_30 PASTA domain K12132 - 2.7.11.1 0.0000000000000000005753 96.0
HFD2_k127_7294666_31 serine threonine protein kinase - - - 0.00000000000000000495 100.0
HFD2_k127_7294666_32 serine threonine protein kinase - - - 0.0000000000000002718 92.0
HFD2_k127_7294666_33 - K01633,K07144 - 1.13.11.81,2.7.4.31,4.1.2.25,5.1.99.8 0.0000000000000007576 91.0
HFD2_k127_7294666_34 methyltransferase - - - 0.0000002019 62.0
HFD2_k127_7294666_35 Protein involved in outer membrane biogenesis K07290 - - 0.0001224 55.0
HFD2_k127_7294666_4 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000264 263.0
HFD2_k127_7294666_5 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001681 279.0
HFD2_k127_7294666_6 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001747 267.0
HFD2_k127_7294666_7 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000004464 251.0
HFD2_k127_7294666_8 Formyl transferase, C-terminal domain K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000004023 251.0
HFD2_k127_7294666_9 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000001263 249.0
HFD2_k127_7313880_0 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000001828 259.0
HFD2_k127_7313880_1 Glycosyl transferase 4-like domain K21011 - - 0.00000000000000000000000000000004046 140.0
HFD2_k127_7313880_2 D-glucuronyl C5-epimerase C-terminus - - - 0.000000000000000000000000007271 124.0
HFD2_k127_7313880_4 Virulence factor - - - 0.00000000004552 66.0
HFD2_k127_7313880_6 FG-GAP repeat - - - 0.000008349 55.0
HFD2_k127_7326967_0 Pfam:CPSase_L_chain K01961,K01965 - 6.3.4.14,6.4.1.2,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 459.0
HFD2_k127_7326967_1 DinB superfamily K07552 - - 0.000000000000000000000000008988 127.0
HFD2_k127_7326967_2 Biotin-lipoyl like - - - 0.0000000000000000001353 91.0
HFD2_k127_7326967_3 DinB family - - - 0.000007089 57.0
HFD2_k127_739020_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 365.0
HFD2_k127_739020_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 319.0
HFD2_k127_739020_10 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000005023 83.0
HFD2_k127_739020_11 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000001693 57.0
HFD2_k127_739020_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000002912 239.0
HFD2_k127_739020_3 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000002449 220.0
HFD2_k127_739020_4 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000005934 204.0
HFD2_k127_739020_5 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000001925 174.0
HFD2_k127_739020_6 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000009098 141.0
HFD2_k127_739020_7 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000248 118.0
HFD2_k127_739020_8 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000004019 110.0
HFD2_k127_739020_9 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000002879 98.0
HFD2_k127_7464305_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 4.294e-233 754.0
HFD2_k127_7464305_1 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 527.0
HFD2_k127_7464305_10 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000001396 153.0
HFD2_k127_7464305_11 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000001517 151.0
HFD2_k127_7464305_12 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000002006 149.0
HFD2_k127_7464305_13 PFAM Lytic transglycosylase catalytic K08309 - - 0.0000000000000000000000000000000003812 153.0
HFD2_k127_7464305_14 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000008333 138.0
HFD2_k127_7464305_15 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000004485 136.0
HFD2_k127_7464305_16 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000004997 131.0
HFD2_k127_7464305_17 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000004819 128.0
HFD2_k127_7464305_18 Tetratricopeptide repeat - - - 0.0000000000000000000000002449 114.0
HFD2_k127_7464305_19 Phage integrase family - - - 0.00000000000000000000001692 113.0
HFD2_k127_7464305_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 432.0
HFD2_k127_7464305_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 408.0
HFD2_k127_7464305_4 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 313.0
HFD2_k127_7464305_5 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001582 299.0
HFD2_k127_7464305_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001509 282.0
HFD2_k127_7464305_7 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000009401 220.0
HFD2_k127_7464305_8 adenosine deaminase K01488,K21053 - 3.5.4.2,3.5.4.4 0.000000000000000000000000000000000000000000000000000000000003673 231.0
HFD2_k127_7464305_9 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000003565 201.0
HFD2_k127_7505061_0 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 0.0 1302.0
HFD2_k127_7505061_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 4.346e-243 762.0
HFD2_k127_7505061_10 Thrombospondin type 3 repeat - - - 0.00000000000000008594 97.0
HFD2_k127_7505061_12 Domain of unknown function (DUF1850) - - - 0.00003604 57.0
HFD2_k127_7505061_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000448 54.0
HFD2_k127_7505061_2 Seven times multi-haem cytochrome CxxCH K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 1.859e-198 631.0
HFD2_k127_7505061_3 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 486.0
HFD2_k127_7505061_4 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 419.0
HFD2_k127_7505061_5 Dystroglycan-type cadherin-like domains. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 402.0
HFD2_k127_7505061_6 Domain of unknown function (DUF4143) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 325.0
HFD2_k127_7505061_7 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000001739 236.0
HFD2_k127_7505061_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000006656 177.0
HFD2_k127_7505061_9 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000000000001571 149.0
HFD2_k127_7540879_0 ABC transporter transmembrane region K06147 - - 3.714e-282 883.0
HFD2_k127_7540879_1 cellulose binding - - - 4.247e-242 778.0
HFD2_k127_7540879_12 Heavy-metal resistance - - - 0.0004649 49.0
HFD2_k127_7540879_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 451.0
HFD2_k127_7540879_3 PDZ domain (Also known as DHR or GLGF) K08372 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 353.0
HFD2_k127_7540879_4 Protein of unknown function (DUF2914) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 307.0
HFD2_k127_7540879_5 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000000000000000000000153 209.0
HFD2_k127_7540879_6 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000000000000000000000000000000000000004463 220.0
HFD2_k127_7540879_7 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0006807,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0020037,GO:0042279,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046906,GO:0048037,GO:0055114,GO:0097159,GO:0097164,GO:0098809,GO:1901363 - 0.00000000000000000000000000000000000000001117 175.0
HFD2_k127_7540879_8 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000004318 142.0
HFD2_k127_7540879_9 Cupin domain - - - 0.0000000000005754 80.0
HFD2_k127_7551908_0 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 1.466e-222 706.0
HFD2_k127_7551908_1 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 492.0
HFD2_k127_7551908_2 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009118 444.0
HFD2_k127_7551908_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000001464 211.0
HFD2_k127_7551908_4 Histidine kinase - - - 0.0000000000000000000000000000000000345 154.0
HFD2_k127_7551908_5 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000194 46.0
HFD2_k127_7572556_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.404e-297 925.0
HFD2_k127_7572556_1 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 3.769e-232 745.0
HFD2_k127_7572556_10 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 297.0
HFD2_k127_7572556_11 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002237 272.0
HFD2_k127_7572556_12 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000002853 258.0
HFD2_k127_7572556_13 Squalene/phytoene synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001012 244.0
HFD2_k127_7572556_14 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000002754 243.0
HFD2_k127_7572556_15 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891,K15546 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000001004 217.0
HFD2_k127_7572556_16 TIGRFAM squalene-associated FAD-dependent desaturase - - - 0.000000000000000000000000000000000000000000000000000000003534 216.0
HFD2_k127_7572556_17 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000005152 123.0
HFD2_k127_7572556_18 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.0000000000000000000000000005327 130.0
HFD2_k127_7572556_19 guanyl-nucleotide exchange factor activity - - - 0.00000000000000000000026 114.0
HFD2_k127_7572556_2 benzoyl-CoA oxygenase K15512 - 1.14.13.208 8.757e-225 704.0
HFD2_k127_7572556_20 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000002842 108.0
HFD2_k127_7572556_21 Ferredoxin - - - 0.00000000000000000005985 103.0
HFD2_k127_7572556_22 Type ii and iii secretion system protein - - - 0.000000004259 69.0
HFD2_k127_7572556_23 Pkd domain containing protein - - - 0.00000001512 69.0
HFD2_k127_7572556_24 - - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009507,GO:0009509,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009575,GO:0009579,GO:0009611,GO:0009628,GO:0009642,GO:0009644,GO:0009765,GO:0009941,GO:0009987,GO:0010206,GO:0010207,GO:0015979,GO:0016020,GO:0016043,GO:0019538,GO:0019684,GO:0019898,GO:0022607,GO:0030091,GO:0031090,GO:0031967,GO:0031969,GO:0031975,GO:0031976,GO:0031984,GO:0034357,GO:0034622,GO:0035448,GO:0042170,GO:0042651,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0055035,GO:0065003,GO:0071704,GO:0071840,GO:1901564 - 0.00001222 58.0
HFD2_k127_7572556_3 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 7.997e-220 694.0
HFD2_k127_7572556_4 Aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000587 482.0
HFD2_k127_7572556_5 NAD dependent epimerase/dehydratase family K05281 - 1.3.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 437.0
HFD2_k127_7572556_6 Ribonuclease E/G family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 445.0
HFD2_k127_7572556_7 ATP ADP translocase K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 387.0
HFD2_k127_7572556_8 proline dipeptidase activity K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 371.0
HFD2_k127_7572556_9 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 303.0
HFD2_k127_7585508_0 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.0 1318.0
HFD2_k127_7585508_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 532.0
HFD2_k127_7585508_10 Cell wall-associated hydrolase (invasion-associated protein) - - - 0.0003577 53.0
HFD2_k127_7585508_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 426.0
HFD2_k127_7585508_3 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009616 377.0
HFD2_k127_7585508_4 PFAM RNA binding S1 domain protein K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 376.0
HFD2_k127_7585508_5 Conserved hypothetical protein 698 - - - 0.00000000000000000000000000000000000000000000000000000000000000000007557 255.0
HFD2_k127_7585508_6 Cysteine dioxygenase type I K00456 - 1.13.11.20 0.0000000000000000000000000000002252 130.0
HFD2_k127_7585508_7 peptidase m48, ste24p - - - 0.0000000000000000000000000000009036 138.0
HFD2_k127_7585508_8 endonuclease activity K07451 - - 0.00000000000000000000002912 116.0
HFD2_k127_7585508_9 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00009549 48.0
HFD2_k127_7666218_0 Diguanylate cyclase, GGDEF domain - - - 0.0000000000000000000000000000000000000006034 150.0
HFD2_k127_7666218_1 - - - - 0.000000000000000000000000000000005817 141.0
HFD2_k127_7682105_0 serine-type peptidase activity K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 606.0
HFD2_k127_7682105_1 Short chain fatty acid transporter K02106 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 501.0
HFD2_k127_7682105_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 342.0
HFD2_k127_7682105_3 Putative metal-binding motif - - - 0.0000000000000000000000000000000000000000000000201 195.0
HFD2_k127_7682105_4 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.0000000000000000000000000000000000000000000001739 188.0
HFD2_k127_7682105_5 PFAM Smr protein MutS2 - - - 0.000000000000000000000000000000001081 139.0
HFD2_k127_7682105_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000001511 134.0
HFD2_k127_7682105_7 Thrombospondin type 3 repeat - - - 0.0000000000000000000000000008124 134.0
HFD2_k127_7682105_8 Subtilase family - - - 0.00000000000000001417 100.0
HFD2_k127_7682105_9 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.0000001373 60.0
HFD2_k127_7790298_0 EVE domain - - - 0.00000000000000000000000000000000000000002696 158.0
HFD2_k127_7790298_1 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000000000000000000000151 133.0
HFD2_k127_7854276_0 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 617.0
HFD2_k127_7854276_1 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 539.0
HFD2_k127_7854276_2 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 539.0
HFD2_k127_8114489_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 507.0
HFD2_k127_8114489_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 496.0
HFD2_k127_8114489_10 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 0.0000001669 55.0
HFD2_k127_8114489_2 formate dehydrogenase (NAD+) activity K00336,K18006 - 1.12.1.2,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 406.0
HFD2_k127_8114489_3 quinone binding K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 390.0
HFD2_k127_8114489_4 NADH-quinone oxidoreductase K00334 - 1.6.5.3 0.000000000000000000000000000000000000009415 164.0
HFD2_k127_8114489_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000008135 139.0
HFD2_k127_8114489_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.0000000000000000000000000000001689 127.0
HFD2_k127_8114489_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000002246 115.0
HFD2_k127_8114489_8 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000003284 93.0
HFD2_k127_8114489_9 Putative metal-binding motif - - - 0.00000000000000002303 96.0
HFD2_k127_8146879_0 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 477.0
HFD2_k127_8146879_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 471.0
HFD2_k127_8146879_10 protein possibly involved in utilization of glycolate and propanediol - - - 0.00000000000000000000000000000000000000001158 160.0
HFD2_k127_8146879_11 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000004827 130.0
HFD2_k127_8146879_12 COG0500 SAM-dependent methyltransferases - - - 0.0000000000000000000000000002295 124.0
HFD2_k127_8146879_13 Transcriptional regulator - - - 0.0000000000000000000000000002584 119.0
HFD2_k127_8146879_14 PFAM thioesterase superfamily K07107 - - 0.0000000000000000000000003732 117.0
HFD2_k127_8146879_2 e3 binding domain K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 327.0
HFD2_k127_8146879_3 LacY proton/sugar symporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 323.0
HFD2_k127_8146879_4 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 312.0
HFD2_k127_8146879_5 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000002115 258.0
HFD2_k127_8146879_6 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000001568 216.0
HFD2_k127_8146879_7 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000003497 225.0
HFD2_k127_8146879_8 Nudix N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000004491 218.0
HFD2_k127_8146879_9 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.00000000000000000000000000000000000000000000000001158 192.0
HFD2_k127_8212524_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02474,K13015 - 1.1.1.136 5.086e-240 750.0
HFD2_k127_8212524_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 580.0
HFD2_k127_8212524_10 Stigma-specific protein, Stig1 - - - 0.0000003613 64.0
HFD2_k127_8212524_11 TIGRFAM conserved repeat domain - - - 0.00000745 60.0
HFD2_k127_8212524_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009966 371.0
HFD2_k127_8212524_3 (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001479 272.0
HFD2_k127_8212524_6 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000002253 91.0
HFD2_k127_8212524_7 serine-type endopeptidase activity K20276 - - 0.0000000000000001274 94.0
HFD2_k127_8212524_8 FG-GAP repeat - - - 0.00000000000003211 88.0
HFD2_k127_8212524_9 Belongs to the peptidase S8 family - - - 0.00000000000004228 87.0
HFD2_k127_8234187_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 1.298e-199 653.0
HFD2_k127_8234187_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009364 569.0
HFD2_k127_8234187_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 537.0
HFD2_k127_8234187_3 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000001391 145.0
HFD2_k127_8234187_4 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000001532 119.0
HFD2_k127_8234187_5 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000005111 106.0
HFD2_k127_8234187_6 Forkhead associated domain K03466 - - 0.00000000002112 71.0
HFD2_k127_8382209_0 Von Willebrand factor type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 430.0
HFD2_k127_8382209_1 Sigma-70 region 2 K03088 - - 0.000000000000000000000003853 111.0
HFD2_k127_8382209_2 Putative zinc-finger - - - 0.00004934 54.0
HFD2_k127_8425459_0 Putative Ig domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002129 245.0
HFD2_k127_8459568_0 COG1062 Zn-dependent alcohol dehydrogenases, class III K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 349.0
HFD2_k127_8459568_1 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.000000000000000000000000000000000000000000000000000000000004865 216.0
HFD2_k127_8482059_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 2.672e-257 820.0
HFD2_k127_8482059_1 DNA polymerase III alpha subunit K02337,K14162 - 2.7.7.7 2.952e-245 798.0
HFD2_k127_8482059_10 Catalyzes the conversion of dihydroorotate to orotate K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 354.0
HFD2_k127_8482059_11 Lytic transglycosylase catalytic K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 325.0
HFD2_k127_8482059_12 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 312.0
HFD2_k127_8482059_13 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 288.0
HFD2_k127_8482059_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000759 298.0
HFD2_k127_8482059_15 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000007473 271.0
HFD2_k127_8482059_16 impB/mucB/samB family K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000009216 267.0
HFD2_k127_8482059_17 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000001402 259.0
HFD2_k127_8482059_18 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000007951 251.0
HFD2_k127_8482059_19 Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000001148 229.0
HFD2_k127_8482059_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 502.0
HFD2_k127_8482059_20 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000002266 231.0
HFD2_k127_8482059_21 PFAM Patatin - - - 0.00000000000000000000000000000000000000000000000000000000002377 230.0
HFD2_k127_8482059_22 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.00000000000000000000000000000000000000000000000000000000014 214.0
HFD2_k127_8482059_23 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356,K03503 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000001213 207.0
HFD2_k127_8482059_24 Efflux ABC transporter permease protein K02004 - - 0.000000000000000000000000000000000000000000000000000003736 214.0
HFD2_k127_8482059_25 COG3119 Arylsulfatase A and related enzymes - - - 0.00000000000000000000000000000000000000000000000005839 205.0
HFD2_k127_8482059_26 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000003763 176.0
HFD2_k127_8482059_27 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000004452 165.0
HFD2_k127_8482059_28 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000001333 169.0
HFD2_k127_8482059_29 Cupin domain - - - 0.00000000000000000000000000000000000000001354 162.0
HFD2_k127_8482059_3 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 487.0
HFD2_k127_8482059_30 PFAM Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000000000000000000000000003082 154.0
HFD2_k127_8482059_31 - - - - 0.0000000000000000000000000000000000006336 143.0
HFD2_k127_8482059_32 PFAM Rhomboid family K19225 - 3.4.21.105 0.000000000000000000000000000000001319 144.0
HFD2_k127_8482059_34 PFAM Helix-turn-helix - - - 0.000000000000000000000000000001645 123.0
HFD2_k127_8482059_35 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000001773 128.0
HFD2_k127_8482059_36 Putative zinc ribbon domain - - - 0.00000000000000000000000000004807 120.0
HFD2_k127_8482059_37 - - - - 0.0000000000000000000000000001014 130.0
HFD2_k127_8482059_38 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000000000000000008384 115.0
HFD2_k127_8482059_39 SNARE associated Golgi protein - - - 0.0000000000000000000004066 106.0
HFD2_k127_8482059_4 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 476.0
HFD2_k127_8482059_40 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000621 99.0
HFD2_k127_8482059_41 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000002358 99.0
HFD2_k127_8482059_42 HD domain - - - 0.0000000000000000005488 89.0
HFD2_k127_8482059_44 Tetratricopeptide repeat - - - 0.0000000000000000009374 99.0
HFD2_k127_8482059_45 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000114 84.0
HFD2_k127_8482059_46 PFAM glycosyl transferase family 39 - - - 0.00000000001387 78.0
HFD2_k127_8482059_47 protein-disulfide reductase activity - - - 0.00000000007299 71.0
HFD2_k127_8482059_48 FecR protein - - - 0.0000000002822 72.0
HFD2_k127_8482059_49 response to antibiotic - - - 0.00001301 54.0
HFD2_k127_8482059_5 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 478.0
HFD2_k127_8482059_50 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0007658 47.0
HFD2_k127_8482059_6 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 435.0
HFD2_k127_8482059_7 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 449.0
HFD2_k127_8482059_8 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029,K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 411.0
HFD2_k127_8482059_9 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 391.0
HFD2_k127_8509579_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 8.913e-283 898.0
HFD2_k127_8509579_1 Dipeptidyl peptidase IV (DPP IV) K01278 - 3.4.14.5 1.653e-195 634.0
HFD2_k127_8509579_10 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 375.0
HFD2_k127_8509579_11 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042,K17468 - 2.9.1.1,4.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 388.0
HFD2_k127_8509579_12 Family 5 K02035,K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 370.0
HFD2_k127_8509579_13 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 345.0
HFD2_k127_8509579_14 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 306.0
HFD2_k127_8509579_15 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 299.0
HFD2_k127_8509579_16 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 310.0
HFD2_k127_8509579_17 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009654 309.0
HFD2_k127_8509579_18 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008768 282.0
HFD2_k127_8509579_19 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000419 248.0
HFD2_k127_8509579_2 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 611.0
HFD2_k127_8509579_20 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006814 265.0
HFD2_k127_8509579_21 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000009038 225.0
HFD2_k127_8509579_22 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000002838 225.0
HFD2_k127_8509579_23 6-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000001036 236.0
HFD2_k127_8509579_24 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000008315 175.0
HFD2_k127_8509579_25 histidine kinase HAMP region domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000003439 157.0
HFD2_k127_8509579_26 Serine phosphatase RsbU, regulator of sigma subunit K07315 - 3.1.3.3 0.000000000000000000000000000000000146 154.0
HFD2_k127_8509579_27 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.00000000000000000000000000002452 130.0
HFD2_k127_8509579_28 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000002001 127.0
HFD2_k127_8509579_29 SatD family (SatD) - - - 0.0000000000000000000000000005137 123.0
HFD2_k127_8509579_3 dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004848 592.0
HFD2_k127_8509579_30 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000006435 126.0
HFD2_k127_8509579_31 Ribonuclease B OB domain K03704 - - 0.000000000000000000000000001144 112.0
HFD2_k127_8509579_32 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000001718 120.0
HFD2_k127_8509579_33 denitrification pathway - - - 0.000000000000000000000000002679 119.0
HFD2_k127_8509579_34 'Cold-shock' DNA-binding domain K03704 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000003176 103.0
HFD2_k127_8509579_35 - - - - 0.000000000000000000003617 109.0
HFD2_k127_8509579_36 PFAM PKD domain containing protein - - - 0.000000000000000004876 100.0
HFD2_k127_8509579_37 Redoxin - - - 0.00000000000000001048 93.0
HFD2_k127_8509579_38 - - - - 0.0000000000000001221 96.0
HFD2_k127_8509579_39 - - - - 0.0000000000000004244 90.0
HFD2_k127_8509579_4 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 538.0
HFD2_k127_8509579_40 - - - - 0.00000000000002961 74.0
HFD2_k127_8509579_41 - - - - 0.00000000000009301 73.0
HFD2_k127_8509579_42 peptidyl-tyrosine sulfation - - - 0.0000000000002708 79.0
HFD2_k127_8509579_43 - - - - 0.000000000000742 72.0
HFD2_k127_8509579_44 SMART Tetratricopeptide - - - 0.000000000008733 74.0
HFD2_k127_8509579_45 Glutaredoxin K03676 - - 0.00000000002354 65.0
HFD2_k127_8509579_46 Protein of unknown function (DUF3187) - - - 0.000000001143 71.0
HFD2_k127_8509579_48 - - - - 0.0000001937 58.0
HFD2_k127_8509579_5 AAA ATPase K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006542 500.0
HFD2_k127_8509579_50 carboxymethylenebutenolidase activity K01061,K06889 - 3.1.1.45 0.0003447 52.0
HFD2_k127_8509579_51 thiolester hydrolase activity - - - 0.0003556 55.0
HFD2_k127_8509579_6 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 432.0
HFD2_k127_8509579_7 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 416.0
HFD2_k127_8509579_8 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 396.0
HFD2_k127_8509579_9 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 396.0
HFD2_k127_8518007_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1259.0
HFD2_k127_8518007_1 Involved in the tonB-independent uptake of proteins - - - 9.937e-216 699.0
HFD2_k127_8518007_2 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006134 425.0
HFD2_k127_8518007_3 Phosphomethylpyrimidine kinase K00868,K00941,K03147,K21219 GO:0008150,GO:0040007 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7,4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000573 274.0
HFD2_k127_8518007_4 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004209 265.0
HFD2_k127_8518007_5 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000008632 227.0
HFD2_k127_8518007_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K21025 - - 0.00000000000000000000000000000000000000000000000000000000000005554 244.0
HFD2_k127_8518007_7 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000003782 204.0
HFD2_k127_8518007_8 arsenate reductase (glutaredoxin) activity K00537 - 1.20.4.1 0.0000000000001373 74.0
HFD2_k127_8574517_0 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001853 281.0
HFD2_k127_8574517_1 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000000000000000000000000000004534 199.0
HFD2_k127_8574517_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000001471 108.0
HFD2_k127_8631307_0 Bacterial protein of unknown function (DUF885) K01322 - 3.4.21.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 568.0
HFD2_k127_8631307_1 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008136 500.0
HFD2_k127_8631307_10 Beta-ketoacyl synthase, C-terminal domain K09458,K14660 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.0000000000000000000000000000000000000007236 159.0
HFD2_k127_8631307_11 methylamine metabolic process K15977 - - 0.0000000000000000000000000000001419 131.0
HFD2_k127_8631307_12 (twin-arginine translocation) pathway signal - - - 0.000000000000000000000000000001236 132.0
HFD2_k127_8631307_13 - - - - 0.00000000000712 75.0
HFD2_k127_8631307_14 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000004778 62.0
HFD2_k127_8631307_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000007538 59.0
HFD2_k127_8631307_2 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 417.0
HFD2_k127_8631307_3 COG0491 Zn-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008197 368.0
HFD2_k127_8631307_4 Permease family K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 343.0
HFD2_k127_8631307_5 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002571 239.0
HFD2_k127_8631307_6 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000001434 245.0
HFD2_k127_8631307_7 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000007377 204.0
HFD2_k127_8631307_8 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000002118 182.0
HFD2_k127_8631307_9 Clostripain family - - - 0.0000000000000000000000000000000000000002974 166.0
HFD2_k127_8678534_0 antibiotic biosynthetic process K01434 - 3.5.1.11 1.533e-232 765.0
HFD2_k127_8678534_1 Belongs to the aldehyde dehydrogenase family K00128,K00130,K10217 - 1.2.1.3,1.2.1.32,1.2.1.8,1.2.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 611.0
HFD2_k127_8678534_10 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008757,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0010340,GO:0016053,GO:0016740,GO:0016741,GO:0016787,GO:0016788,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032259,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197 0.000007172 58.0
HFD2_k127_8678534_11 Carboxypeptidase regulatory-like domain - - - 0.0006485 52.0
HFD2_k127_8678534_2 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 430.0
HFD2_k127_8678534_3 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 320.0
HFD2_k127_8678534_4 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000003605 214.0
HFD2_k127_8678534_5 Translation initiation inhibitor, yjgF family K15067 - 3.5.99.5 0.000000000000000000000000000000000000000000000000007533 184.0
HFD2_k127_8678534_6 Putative cyclase K07130 - 3.5.1.9 0.000000000000000000000000000000000000000000002419 172.0
HFD2_k127_8678534_7 Plasmid stabilization system - - - 0.0000000000000000000000000000003534 126.0
HFD2_k127_8678534_8 toxin-antitoxin pair type II binding - - - 0.0000000000000000000000000000005532 125.0
HFD2_k127_8678534_9 - - - - 0.00000000000003877 74.0
HFD2_k127_942083_0 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 632.0
HFD2_k127_942083_1 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 446.0
HFD2_k127_942083_2 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 349.0
HFD2_k127_942083_3 Protease prsW family - - - 0.00000000000000000000000000000000000000000000000000000000009156 226.0
HFD2_k127_942083_4 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000007632 168.0
HFD2_k127_942083_5 domain protein K20276 - - 0.000000000000000000007423 109.0
HFD2_k127_942270_0 Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 416.0
HFD2_k127_942270_1 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004927 280.0
HFD2_k127_942270_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000007063 224.0
HFD2_k127_942719_0 Glycosyl transferase family 2 K10012,K20534 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 294.0
HFD2_k127_942719_1 TIGRFAM YD repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 325.0
HFD2_k127_942719_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.000000000000000000000000000000000000000000004631 188.0
HFD2_k127_942719_3 glycosyl transferase, family 39 - - - 0.0000000000000000000000000000000000000000007163 177.0
HFD2_k127_942719_4 Parallel beta-helix repeat-containing protein - - - 0.000000000802 72.0
HFD2_k127_942719_5 PKD domain - - - 0.0005853 54.0