Overview

ID MAG01645
Name HFD2_bin.33
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Bacteroidota_A
Class UBA10030
Order UBA10030
Family UBA6906
Genus UBA6906
Species
Assembly information
Completeness (%) 100.0
Contamination (%) 0.0
GC content (%) 62.0
N50 (bp) 136,562
Genome size (bp) 4,263,222

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3270

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_1002314_0 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity K01955 - 6.3.5.5 0.0 1337.0
HFD2_k127_1002314_1 nodulation K00612 - - 4.528e-302 935.0
HFD2_k127_1002314_10 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000001532 186.0
HFD2_k127_1002314_11 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000006801 168.0
HFD2_k127_1002314_12 methyltransferase - - - 0.0000000000000000000000000000003342 134.0
HFD2_k127_1002314_13 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000003933 98.0
HFD2_k127_1002314_15 - - - - 0.000000000000001145 78.0
HFD2_k127_1002314_16 PFAM Polysaccharide export protein K01991 - - 0.00000000001092 75.0
HFD2_k127_1002314_17 long-chain fatty acid transport protein - - - 0.00001363 56.0
HFD2_k127_1002314_18 protein involved in exopolysaccharide biosynthesis - - - 0.000286 52.0
HFD2_k127_1002314_2 Belongs to the CarA family K01955,K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 449.0
HFD2_k127_1002314_3 -O-antigen K02847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 343.0
HFD2_k127_1002314_4 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 309.0
HFD2_k127_1002314_5 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002246 293.0
HFD2_k127_1002314_6 Glycosyl transferase, WecB TagA CpsF family K05946 - 2.4.1.187 0.00000000000000000000000000000000000000000000000000000000000000000005598 252.0
HFD2_k127_1002314_7 extracellular polysaccharide biosynthetic process K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000003136 248.0
HFD2_k127_1002314_8 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000004862 213.0
HFD2_k127_1002314_9 Belongs to the glycosyl hydrolase 18 family K01183 - 3.2.1.14 0.000000000000000000000000000000000000000000000000001377 206.0
HFD2_k127_106568_0 Glycosyltransferase family 36 K18675 - 2.4.1.280 0.0 1226.0
HFD2_k127_106568_1 Response regulator, receiver K01007 - 2.7.9.2 0.0 1170.0
HFD2_k127_106568_10 Phage tail sheath C-terminal domain - - - 2.03e-240 759.0
HFD2_k127_106568_100 PFAM T4 bacteriophage base plate protein - - - 0.000000000000000000000000000000000000000000000002355 185.0
HFD2_k127_106568_101 Cytochrome oxidase assembly protein K02259 - - 0.000000000000000000000000000000000000000000000005073 185.0
HFD2_k127_106568_102 Domain of unknown function (DUF4157) - - - 0.00000000000000000000000000000000000000000000002935 184.0
HFD2_k127_106568_103 ABC transporter - - - 0.00000000000000000000000000000000000000000000007616 175.0
HFD2_k127_106568_104 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.00000000000000000000000000000000000000000000008624 174.0
HFD2_k127_106568_105 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000007231 168.0
HFD2_k127_106568_106 ROK family - - - 0.00000000000000000000000000000000000000000000978 179.0
HFD2_k127_106568_107 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000001206 170.0
HFD2_k127_106568_108 ATPase involved in DNA repair K02057 - - 0.00000000000000000000000000000000000000000001353 190.0
HFD2_k127_106568_109 Elongation factor P K02356 - - 0.00000000000000000000000000000000000000000002842 168.0
HFD2_k127_106568_11 FMN binding - - - 3.157e-239 749.0
HFD2_k127_106568_110 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000001064 171.0
HFD2_k127_106568_111 Gene 25-like lysozyme K06903 - - 0.000000000000000000000000000000000000000003421 158.0
HFD2_k127_106568_112 - - - - 0.0000000000000000000000000000000000000001931 171.0
HFD2_k127_106568_113 cellulose binding - - - 0.0000000000000000000000000000000000000004822 165.0
HFD2_k127_106568_114 - - - - 0.000000000000000000000000000000000000009934 155.0
HFD2_k127_106568_115 cell redox homeostasis K02199,K03671 - - 0.000000000000000000000000000000000000313 147.0
HFD2_k127_106568_116 PAAR motif - - - 0.0000000000000000000000000000000000006391 152.0
HFD2_k127_106568_117 Cytochrome c - - - 0.0000000000000000000000000000000000009279 150.0
HFD2_k127_106568_118 LysM domain - - - 0.000000000000000000000000000000000001161 143.0
HFD2_k127_106568_119 acetyltransferase - - - 0.0000000000000000000000000000000001591 147.0
HFD2_k127_106568_12 Baseplate J-like protein - - - 7.162e-233 748.0
HFD2_k127_106568_120 Phage late control gene D protein (GPD) K11904 - - 0.0000000000000000000000000000000002205 151.0
HFD2_k127_106568_121 Putative peptidoglycan binding domain - - - 0.0000000000000000000000000000000004461 139.0
HFD2_k127_106568_122 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000001455 140.0
HFD2_k127_106568_123 spectrin binding K15502,K15503,K16717 GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0070013 - 0.00000000000000000000000000001741 135.0
HFD2_k127_106568_124 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.0000000000000000000000000001969 133.0
HFD2_k127_106568_125 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000002063 117.0
HFD2_k127_106568_126 calcium- and calmodulin-responsive adenylate cyclase activity K01179 - 3.2.1.4 0.0000000000000000000000000002473 134.0
HFD2_k127_106568_127 cell septum assembly K02487,K06596,K08372 - - 0.0000000000000000000000004319 121.0
HFD2_k127_106568_128 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000009925 115.0
HFD2_k127_106568_129 redox-active disulfide protein 2 - - - 0.000000000000000000000006086 103.0
HFD2_k127_106568_13 TonB-dependent receptor - - - 7.962e-226 733.0
HFD2_k127_106568_130 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00000000000000000000009453 109.0
HFD2_k127_106568_131 - - - - 0.0000000000000000000001715 100.0
HFD2_k127_106568_132 cellulase activity K01186,K01197,K05988,K11931,K21449 - 3.2.1.11,3.2.1.18,3.2.1.35 0.000000000000000000001549 112.0
HFD2_k127_106568_134 - - - - 0.0000000000000000000025 100.0
HFD2_k127_106568_135 Family of unknown function (DUF5458) - - - 0.00000000000000000002043 105.0
HFD2_k127_106568_136 Belongs to the glycosyl hydrolase 13 family - - - 0.00000000000000000002069 106.0
HFD2_k127_106568_137 cell septum assembly K02487,K06596,K08372 - - 0.00000000000000000003095 105.0
HFD2_k127_106568_138 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000003422 103.0
HFD2_k127_106568_139 Serine aminopeptidase, S33 - - - 0.0000000000000000001171 100.0
HFD2_k127_106568_14 PFAM ATPase family associated with various cellular activities (AAA) - - - 2.74e-219 698.0
HFD2_k127_106568_140 heavy metal translocating P-type ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000000000005264 89.0
HFD2_k127_106568_141 phosphorelay signal transduction system K03413 - - 0.000000000000000005927 92.0
HFD2_k127_106568_142 cell redox homeostasis - - - 0.00000000000000000846 95.0
HFD2_k127_106568_143 Parallel beta-helix repeat-containing protein - - - 0.00000000000000001344 97.0
HFD2_k127_106568_144 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000007466 91.0
HFD2_k127_106568_145 - - - - 0.0000000000000001897 87.0
HFD2_k127_106568_146 Phospholipid methyltransferase - - - 0.0000000000000002868 91.0
HFD2_k127_106568_147 Hydrolases of the alpha beta superfamily K06889 - - 0.000000000000002716 88.0
HFD2_k127_106568_148 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000003724 87.0
HFD2_k127_106568_149 Protein of unknown function (DUF1501) - - - 0.000000000000004011 89.0
HFD2_k127_106568_15 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0016661,GO:0016662,GO:0016966,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044237,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0097159,GO:0098809,GO:1901363 1.7.2.2 1.858e-211 670.0
HFD2_k127_106568_151 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.0000000000004774 75.0
HFD2_k127_106568_152 Rhomboid family - - - 0.00000000000282 81.0
HFD2_k127_106568_153 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000001471 65.0
HFD2_k127_106568_154 protocatechuate 3,4-dioxygenase activity - - - 0.00000000002027 72.0
HFD2_k127_106568_155 Fibronectin type 3 domain - - - 0.00000000005431 78.0
HFD2_k127_106568_156 Y_Y_Y domain - - - 0.0000000003406 67.0
HFD2_k127_106568_157 - - - - 0.000000007491 67.0
HFD2_k127_106568_158 pyrroloquinoline quinone binding - - - 0.00000002984 67.0
HFD2_k127_106568_159 - - - - 0.0000005113 61.0
HFD2_k127_106568_16 cellulose binding - - - 1.287e-194 638.0
HFD2_k127_106568_160 - - - - 0.0000006707 57.0
HFD2_k127_106568_161 ATPase P K01533 - 3.6.3.4 0.00001221 48.0
HFD2_k127_106568_162 E1-E2 ATPase K01533 - 3.6.3.4 0.00001726 51.0
HFD2_k127_106568_164 type VI secretion protein - - - 0.00005092 55.0
HFD2_k127_106568_165 - - - - 0.0000663 50.0
HFD2_k127_106568_166 PBS lyase HEAT-like repeat - - - 0.00008575 52.0
HFD2_k127_106568_167 Proprotein convertase P-domain - - - 0.0001579 55.0
HFD2_k127_106568_168 Cupin 2, conserved barrel domain protein - - - 0.0003677 49.0
HFD2_k127_106568_169 Putative transmembrane protein (PGPGW) - - - 0.0004795 46.0
HFD2_k127_106568_17 beta-galactosidase activity K01190 - 3.2.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009668 632.0
HFD2_k127_106568_18 Phospholipase B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 595.0
HFD2_k127_106568_19 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 607.0
HFD2_k127_106568_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K15022,K18331 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.12.1.3,1.17.1.10,1.6.5.3 0.0 1158.0
HFD2_k127_106568_20 Major Facilitator Superfamily K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 585.0
HFD2_k127_106568_21 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 597.0
HFD2_k127_106568_22 transmembrane transporter activity K13021 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 572.0
HFD2_k127_106568_23 PFAM Bile acid sodium symporter K03325,K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000779 538.0
HFD2_k127_106568_24 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 527.0
HFD2_k127_106568_25 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 534.0
HFD2_k127_106568_26 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 523.0
HFD2_k127_106568_27 Late control gene D protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 496.0
HFD2_k127_106568_28 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 492.0
HFD2_k127_106568_29 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 479.0
HFD2_k127_106568_3 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0 1016.0
HFD2_k127_106568_30 Anaerobic sulfatase maturase K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 472.0
HFD2_k127_106568_31 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 471.0
HFD2_k127_106568_32 Sulfatase K01133 - 3.1.6.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 469.0
HFD2_k127_106568_33 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007645 447.0
HFD2_k127_106568_34 Glycosyl Hydrolase Family 88 K15532 - 3.2.1.172 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 451.0
HFD2_k127_106568_35 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 455.0
HFD2_k127_106568_36 Psort location CytoplasmicMembrane, score 10.00 K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 422.0
HFD2_k127_106568_37 fimbrial usher porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 410.0
HFD2_k127_106568_38 Alpha-L-fucosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 408.0
HFD2_k127_106568_39 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 388.0
HFD2_k127_106568_4 TonB-dependent receptor - - - 5.354e-300 951.0
HFD2_k127_106568_40 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 396.0
HFD2_k127_106568_41 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 377.0
HFD2_k127_106568_42 purine nucleotide biosynthetic process K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 381.0
HFD2_k127_106568_43 COG1680 Beta-lactamase class C and other penicillin binding proteins K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 386.0
HFD2_k127_106568_44 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 374.0
HFD2_k127_106568_45 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 381.0
HFD2_k127_106568_46 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 375.0
HFD2_k127_106568_47 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 367.0
HFD2_k127_106568_48 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 379.0
HFD2_k127_106568_49 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 356.0
HFD2_k127_106568_5 Glycosyl-hydrolase 97 C-terminal, oligomerisation K01187 - 3.2.1.20 1.122e-294 919.0
HFD2_k127_106568_50 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008973 347.0
HFD2_k127_106568_51 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 334.0
HFD2_k127_106568_52 protein secretion K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 354.0
HFD2_k127_106568_53 dihydrofolate reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 334.0
HFD2_k127_106568_54 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 340.0
HFD2_k127_106568_55 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 350.0
HFD2_k127_106568_56 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 327.0
HFD2_k127_106568_57 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 319.0
HFD2_k127_106568_58 TAP-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 325.0
HFD2_k127_106568_59 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 336.0
HFD2_k127_106568_6 heavy metal translocating P-type ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 1.416e-283 889.0
HFD2_k127_106568_60 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 298.0
HFD2_k127_106568_61 Protein of unknown function (DUF4255) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 309.0
HFD2_k127_106568_62 Aminotransferase class-III K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008951 302.0
HFD2_k127_106568_63 Baseplate assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001681 274.0
HFD2_k127_106568_64 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002834 273.0
HFD2_k127_106568_65 Putative peptidoglycan binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003969 264.0
HFD2_k127_106568_66 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000863 262.0
HFD2_k127_106568_67 PFAM oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000171 266.0
HFD2_k127_106568_68 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009031 259.0
HFD2_k127_106568_7 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 1.546e-265 835.0
HFD2_k127_106568_70 denitrification pathway K15876 GO:0005575,GO:0006807,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0031224,GO:0044425 - 0.000000000000000000000000000000000000000000000000000000000000000000000005731 248.0
HFD2_k127_106568_71 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001121 263.0
HFD2_k127_106568_72 Glyco_18 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001579 266.0
HFD2_k127_106568_73 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001995 259.0
HFD2_k127_106568_74 protein-disulfide reductase activity K04084,K06196 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000003522 238.0
HFD2_k127_106568_75 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000007024 264.0
HFD2_k127_106568_76 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000008795 240.0
HFD2_k127_106568_77 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000006278 239.0
HFD2_k127_106568_78 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001959 252.0
HFD2_k127_106568_79 surface antigen - - - 0.00000000000000000000000000000000000000000000000000000000000000141 233.0
HFD2_k127_106568_8 alpha-L-rhamnosidase - - - 1.001e-263 848.0
HFD2_k127_106568_80 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000003519 224.0
HFD2_k127_106568_81 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000006834 216.0
HFD2_k127_106568_82 alpha-galactosidase K07407 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000007667 238.0
HFD2_k127_106568_84 Heparinase II/III N-terminus - - - 0.000000000000000000000000000000000000000000000000000000000005564 232.0
HFD2_k127_106568_85 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000811 211.0
HFD2_k127_106568_86 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000001018 221.0
HFD2_k127_106568_87 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000002721 211.0
HFD2_k127_106568_88 hydrolases or acyltransferases alpha beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000008202 216.0
HFD2_k127_106568_89 PFAM Methyltransferase type 12 - - - 0.000000000000000000000000000000000000000000000000000000001728 208.0
HFD2_k127_106568_9 Peptidase family M3 K01284,K01414 - 3.4.15.5,3.4.24.70 1.366e-253 803.0
HFD2_k127_106568_90 extracellular matrix structural constituent - - - 0.00000000000000000000000000000000000000000000000000000000264 221.0
HFD2_k127_106568_91 Elongator protein 3, MiaB family, Radical SAM K22318 - - 0.000000000000000000000000000000000000000000000000000000004978 219.0
HFD2_k127_106568_92 PA14 domain - - - 0.000000000000000000000000000000000000000000000000000000027 220.0
HFD2_k127_106568_93 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 0.0000000000000000000000000000000000000000000000000000004836 197.0
HFD2_k127_106568_94 Peptidogalycan biosysnthesis/recognition K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.47 0.0000000000000000000000000000000000000000000000000000005288 205.0
HFD2_k127_106568_95 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000001958 202.0
HFD2_k127_106568_96 Predicted membrane protein (DUF2318) K09005 - - 0.0000000000000000000000000000000000000000000000000003309 192.0
HFD2_k127_106568_97 - - - - 0.0000000000000000000000000000000000000000000000000695 192.0
HFD2_k127_106568_98 PFAM PPIC-type K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000001205 184.0
HFD2_k127_106568_99 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000000001345 181.0
HFD2_k127_1168645_0 Response regulator, receiver K01007 - 2.7.9.2 0.0 1391.0
HFD2_k127_1168645_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 2.943e-308 971.0
HFD2_k127_1168645_10 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 534.0
HFD2_k127_1168645_11 FAD linked oxidases, C-terminal domain K00104,K18930 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 521.0
HFD2_k127_1168645_12 transcription antitermination K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009349 516.0
HFD2_k127_1168645_13 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007244 473.0
HFD2_k127_1168645_14 phosphorelay signal transduction system K02437 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005571 455.0
HFD2_k127_1168645_15 4 iron, 4 sulfur cluster binding K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 449.0
HFD2_k127_1168645_16 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 452.0
HFD2_k127_1168645_17 COGs COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 453.0
HFD2_k127_1168645_18 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007183 416.0
HFD2_k127_1168645_19 IgA Peptidase M64 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 416.0
HFD2_k127_1168645_2 Peptidase, M16 K07263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 5.458e-271 862.0
HFD2_k127_1168645_20 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 403.0
HFD2_k127_1168645_21 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 411.0
HFD2_k127_1168645_22 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 395.0
HFD2_k127_1168645_23 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 396.0
HFD2_k127_1168645_24 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008816 389.0
HFD2_k127_1168645_25 nicotinamide-nucleotide amidase activity K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 371.0
HFD2_k127_1168645_26 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 373.0
HFD2_k127_1168645_27 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 361.0
HFD2_k127_1168645_28 heat shock protein binding - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 310.0
HFD2_k127_1168645_29 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000001216 274.0
HFD2_k127_1168645_3 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 3.722e-258 811.0
HFD2_k127_1168645_30 Cell division ATP-binding protein ftsE K09812 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004905 265.0
HFD2_k127_1168645_31 Belongs to the PdxA family K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000007979 263.0
HFD2_k127_1168645_32 Fumarylacetoacetate (FAA) hydrolase family K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000001095 253.0
HFD2_k127_1168645_33 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000003945 247.0
HFD2_k127_1168645_34 response to copper ion K07156 - - 0.000000000000000000000000000000000000000000000000000000000000000000003176 257.0
HFD2_k127_1168645_35 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000001278 244.0
HFD2_k127_1168645_36 phosphorelay signal transduction system K02437 - - 0.0000000000000000000000000000000000000000000000000000000000000002203 231.0
HFD2_k127_1168645_37 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000005715 223.0
HFD2_k127_1168645_38 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000000000000000000000222 207.0
HFD2_k127_1168645_39 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000009695 207.0
HFD2_k127_1168645_4 glutamate dehydrogenase [NAD(P)+] activity K00262 - 1.4.1.4 2.924e-242 754.0
HFD2_k127_1168645_40 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000001245 211.0
HFD2_k127_1168645_41 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000001712 201.0
HFD2_k127_1168645_42 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000009121 182.0
HFD2_k127_1168645_43 rRNA binding K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000001534 176.0
HFD2_k127_1168645_44 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000002499 178.0
HFD2_k127_1168645_45 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000001073 166.0
HFD2_k127_1168645_46 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000008225 148.0
HFD2_k127_1168645_47 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000009497 147.0
HFD2_k127_1168645_48 - - - - 0.0000000000000000000000000000000000009765 145.0
HFD2_k127_1168645_49 biotin transmembrane transporter activity K03523 - - 0.0000000000000000000000000000000001603 141.0
HFD2_k127_1168645_5 Histidine kinase K02482 - 2.7.13.3 5.851e-227 718.0
HFD2_k127_1168645_50 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000002368 123.0
HFD2_k127_1168645_51 DNA recombination K03546,K03631 - - 0.00000000000000000000000000002948 132.0
HFD2_k127_1168645_52 Binds the 23S rRNA K02909 GO:0008150,GO:0040007 - 0.00000000000000000000000000007504 116.0
HFD2_k127_1168645_53 PFAM phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000000000000004542 120.0
HFD2_k127_1168645_54 - - - - 0.000000000000000000000000002386 118.0
HFD2_k127_1168645_55 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000004436 111.0
HFD2_k127_1168645_56 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001902 104.0
HFD2_k127_1168645_59 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000008836 93.0
HFD2_k127_1168645_6 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 2.924e-214 673.0
HFD2_k127_1168645_60 Modulates RecA activity K03565 - - 0.00000000000000000008307 100.0
HFD2_k127_1168645_61 - - - - 0.000000000000000174 86.0
HFD2_k127_1168645_62 NifU-like domain - - - 0.0000000000000004805 82.0
HFD2_k127_1168645_63 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.000000000001163 69.0
HFD2_k127_1168645_64 His Kinase A (phosphoacceptor) domain - - - 0.00000002371 60.0
HFD2_k127_1168645_65 - - - - 0.0000001254 61.0
HFD2_k127_1168645_66 Belongs to the ComB family K05979 - 3.1.3.71 0.0000003494 61.0
HFD2_k127_1168645_7 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 1.048e-194 616.0
HFD2_k127_1168645_8 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 546.0
HFD2_k127_1168645_9 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639,K00652 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009007 536.0
HFD2_k127_1476931_0 carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 3.69e-257 800.0
HFD2_k127_1476931_1 - - - - 3.508e-252 819.0
HFD2_k127_1476931_10 LysM domain K08307,K12204 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 489.0
HFD2_k127_1476931_11 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K16950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 436.0
HFD2_k127_1476931_12 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 387.0
HFD2_k127_1476931_13 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 388.0
HFD2_k127_1476931_14 coenzyme F420 hydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006272 351.0
HFD2_k127_1476931_15 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 341.0
HFD2_k127_1476931_16 Fungal trichothecene efflux pump (TRI12) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005252 332.0
HFD2_k127_1476931_17 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 316.0
HFD2_k127_1476931_18 gtp cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000002422 267.0
HFD2_k127_1476931_19 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001704 265.0
HFD2_k127_1476931_2 DNA-templated transcription, termination K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 1.525e-226 706.0
HFD2_k127_1476931_20 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000004 257.0
HFD2_k127_1476931_21 Metal dependent phosphohydrolases with conserved 'HD' motif. K06951 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009858 243.0
HFD2_k127_1476931_22 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000001108 255.0
HFD2_k127_1476931_23 PFAM oxidoreductase FAD NAD(P)-binding domain protein K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006367 245.0
HFD2_k127_1476931_24 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000002801 244.0
HFD2_k127_1476931_25 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004457 247.0
HFD2_k127_1476931_26 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000313 225.0
HFD2_k127_1476931_27 peroxiredoxin activity K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000002391 205.0
HFD2_k127_1476931_28 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000001746 197.0
HFD2_k127_1476931_29 cell envelope organization K05807,K06381 - - 0.000000000000000000000000000000000000000000000000006387 206.0
HFD2_k127_1476931_3 helicase K03657 - 3.6.4.12 4.534e-207 667.0
HFD2_k127_1476931_30 KR domain - - - 0.00000000000000000000000000000000000000000000000006517 195.0
HFD2_k127_1476931_31 AhpC/TSA family K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000006248 177.0
HFD2_k127_1476931_32 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000001895 179.0
HFD2_k127_1476931_33 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000124 171.0
HFD2_k127_1476931_34 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K13531 - 2.1.1.63 0.000000000000000000000000000000000000000000003611 169.0
HFD2_k127_1476931_35 Endonuclease I - - - 0.000000000000000000000000000000000000000000009834 190.0
HFD2_k127_1476931_36 - - - - 0.00000000000000000000000000000000000000000005532 179.0
HFD2_k127_1476931_37 Ferredoxin - - - 0.000000000000000000000000000000000000006697 148.0
HFD2_k127_1476931_38 Belongs to the peptidase S8 family K12287 - - 0.00000000000000000000000000000000000001182 170.0
HFD2_k127_1476931_39 Hydrogenase maturation protease - - - 0.0000000000000000000000000002045 119.0
HFD2_k127_1476931_4 DNA polymerase K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 614.0
HFD2_k127_1476931_41 Protein of unknown function (DUF1207) - - - 0.000000000000000000000000006517 127.0
HFD2_k127_1476931_42 polysaccharide catabolic process K01179 - 3.2.1.4 0.000000000000000000000003213 108.0
HFD2_k127_1476931_43 Predicted periplasmic lipoprotein (DUF2279) - - - 0.000000000000000000003435 105.0
HFD2_k127_1476931_44 Cell wall-active antibiotics response 4TMS YvqF K11622 - - 0.00000000000006813 79.0
HFD2_k127_1476931_45 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000002126 73.0
HFD2_k127_1476931_46 Protein of unknown function (DUF1207) - - - 0.0000000001906 74.0
HFD2_k127_1476931_47 Outer membrane protein beta-barrel domain - - - 0.0000000006619 70.0
HFD2_k127_1476931_48 Bacterial Ig-like domain (group 1) - - - 0.00000006561 68.0
HFD2_k127_1476931_49 ATP-independent chaperone mediated protein folding K06006,K07803 - - 0.00001441 58.0
HFD2_k127_1476931_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 565.0
HFD2_k127_1476931_50 Outer membrane protein beta-barrel domain - - - 0.0000351 54.0
HFD2_k127_1476931_51 PAS domain - - - 0.00004892 54.0
HFD2_k127_1476931_6 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 554.0
HFD2_k127_1476931_7 acyl-CoA dehydrogenase activity K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 524.0
HFD2_k127_1476931_8 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 506.0
HFD2_k127_1476931_9 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 487.0
HFD2_k127_160904_0 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 590.0
HFD2_k127_160904_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 578.0
HFD2_k127_160904_10 - - - - 0.00000000000000000000000000000002044 130.0
HFD2_k127_160904_11 - - - - 0.0000000000000000000000000000006585 130.0
HFD2_k127_160904_12 Exodeoxyribonuclease III - - - 0.0000000000000000000004378 112.0
HFD2_k127_160904_13 Belongs to the glycosyl hydrolase 13 family - - - 0.0000000000000000000145 108.0
HFD2_k127_160904_2 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009043 407.0
HFD2_k127_160904_3 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 330.0
HFD2_k127_160904_4 antibiotic catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000001757 247.0
HFD2_k127_160904_5 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000001116 191.0
HFD2_k127_160904_6 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000004331 184.0
HFD2_k127_160904_7 hydrolase, family 25 - - - 0.000000000000000000000000000000000000000003538 180.0
HFD2_k127_160904_8 exo-alpha-(2->6)-sialidase activity K01186 - 3.2.1.18 0.000000000000000000000000000000000000008013 169.0
HFD2_k127_160904_9 3-demethylubiquinone-9 3-O-methyltransferase activity K03428 - 2.1.1.11 0.00000000000000000000000000000000418 137.0
HFD2_k127_1775266_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 2.192e-200 633.0
HFD2_k127_1775266_1 amino acid activation for nonribosomal peptide biosynthetic process K03651 - 3.1.4.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 582.0
HFD2_k127_1775266_10 Psort location Cytoplasmic, score - - - 0.0007228 51.0
HFD2_k127_1775266_2 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 537.0
HFD2_k127_1775266_3 Stage II sporulation protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 506.0
HFD2_k127_1775266_4 Belongs to the glycosyl hydrolase 5 (cellulase A) family K19355 - 3.2.1.78 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 496.0
HFD2_k127_1775266_5 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000177 223.0
HFD2_k127_1775266_6 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.0000000000000000000000000000000000000000000000000000000000003227 216.0
HFD2_k127_1775266_7 cytokinin biosynthetic process K06966 - 3.2.2.10 0.0000000000000000000000000000000000000002233 154.0
HFD2_k127_1775266_8 Belongs to the GcvT family K00605,K06980 - 2.1.2.10 0.000000000000000000000000000000000000003531 161.0
HFD2_k127_1775266_9 membrane transporter protein K07090 - - 0.000002769 57.0
HFD2_k127_1848562_0 hydrolase, family 65, central catalytic - - - 9.003e-275 865.0
HFD2_k127_1848562_1 Domain of unknown function (DUF4976) - - - 3.504e-250 782.0
HFD2_k127_1848562_10 purine nucleotide biosynthetic process K02529,K05499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 402.0
HFD2_k127_1848562_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 386.0
HFD2_k127_1848562_12 cellulase activity K01179,K01361,K13277,K21449 - 3.2.1.4,3.4.21.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 401.0
HFD2_k127_1848562_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009073 374.0
HFD2_k127_1848562_14 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 342.0
HFD2_k127_1848562_15 O-methyltransferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 325.0
HFD2_k127_1848562_16 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 318.0
HFD2_k127_1848562_17 purine nucleotide biosynthetic process K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006806 316.0
HFD2_k127_1848562_18 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006707 306.0
HFD2_k127_1848562_19 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008539 297.0
HFD2_k127_1848562_2 TonB dependent receptor - - - 7.969e-230 748.0
HFD2_k127_1848562_20 SusD family K21572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001705 273.0
HFD2_k127_1848562_21 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000004505 254.0
HFD2_k127_1848562_22 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000002464 232.0
HFD2_k127_1848562_23 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000003622 231.0
HFD2_k127_1848562_24 chitin binding - - - 0.0000000000000000000000000000000000000000000000000000000000001248 230.0
HFD2_k127_1848562_25 deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000002431 215.0
HFD2_k127_1848562_26 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000003526 207.0
HFD2_k127_1848562_27 peptidase activity K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000006174 191.0
HFD2_k127_1848562_28 Domain of unknown function (DUF5110) K01811 - 3.2.1.177 0.000000000000000000000000000000000000000000000003315 176.0
HFD2_k127_1848562_29 - - - - 0.000000000000000000000000000000000000000000004354 168.0
HFD2_k127_1848562_3 symporter activity K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 579.0
HFD2_k127_1848562_30 phospholipase Carboxylesterase - - - 0.00000000000000000000000000000000000000000001403 186.0
HFD2_k127_1848562_32 Transglycosylase associated protein - - - 0.000000000000000000000000000002184 121.0
HFD2_k127_1848562_33 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000003241 122.0
HFD2_k127_1848562_34 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000001956 116.0
HFD2_k127_1848562_36 cellulose binding - - - 0.00000000000000000000006411 115.0
HFD2_k127_1848562_37 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000006706 103.0
HFD2_k127_1848562_38 Belongs to the peptidase S8 family K01361,K20276 - 3.4.21.96 0.0000000000000000000002216 115.0
HFD2_k127_1848562_39 Domain of unknown function (DU1801) - - - 0.000000000000000000001502 99.0
HFD2_k127_1848562_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 561.0
HFD2_k127_1848562_40 histone H2A K63-linked ubiquitination K08884 - 2.7.11.1 0.000000000000000000112 89.0
HFD2_k127_1848562_41 cellulose binding - - - 0.000000000000000003334 100.0
HFD2_k127_1848562_42 xylanase chitin deacetylase - - - 0.000000000000000009192 96.0
HFD2_k127_1848562_43 protein secretion K09800 - - 0.0000000000003854 78.0
HFD2_k127_1848562_44 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000004622 69.0
HFD2_k127_1848562_45 amine dehydrogenase activity - - - 0.000000000007848 70.0
HFD2_k127_1848562_46 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000004147 63.0
HFD2_k127_1848562_47 - - - - 0.000000004609 66.0
HFD2_k127_1848562_49 - - - - 0.00003749 51.0
HFD2_k127_1848562_5 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 477.0
HFD2_k127_1848562_6 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 493.0
HFD2_k127_1848562_7 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 475.0
HFD2_k127_1848562_8 cAMP biosynthetic process K00870,K12132 - 2.7.1.37,2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 464.0
HFD2_k127_1848562_9 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 435.0
HFD2_k127_1873215_0 Amylo-alpha-1,6-glucosidase - - - 0.0 1147.0
HFD2_k127_1873215_1 Trehalase K03931 - - 0.0 1023.0
HFD2_k127_1873215_10 Alpha mannosidase, middle domain K01191 - 3.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 455.0
HFD2_k127_1873215_11 Trehalase K03931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 428.0
HFD2_k127_1873215_12 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 392.0
HFD2_k127_1873215_13 aminopeptidase N - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 344.0
HFD2_k127_1873215_14 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 331.0
HFD2_k127_1873215_15 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 316.0
HFD2_k127_1873215_16 symporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000113 300.0
HFD2_k127_1873215_17 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005795 260.0
HFD2_k127_1873215_18 cellulose binding K00505 - 1.14.18.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000763 276.0
HFD2_k127_1873215_19 - - - - 0.00000000000000000000000000000000000000000000000000000000008932 229.0
HFD2_k127_1873215_2 beta-galactosidase activity - - - 1.753e-259 841.0
HFD2_k127_1873215_20 COG2801 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000006053 190.0
HFD2_k127_1873215_21 Group II intron, maturase-specific domain - - - 0.000000000000000000000000000002824 123.0
HFD2_k127_1873215_22 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.000000000000000000000000000005572 133.0
HFD2_k127_1873215_23 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000009144 118.0
HFD2_k127_1873215_24 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000006114 99.0
HFD2_k127_1873215_26 Membrane-bound dehydrogenase domain - - - 0.00000000006475 76.0
HFD2_k127_1873215_27 Y_Y_Y domain K11527 - 2.7.13.3 0.00000000008938 66.0
HFD2_k127_1873215_29 Belongs to the 'phage' integrase family - - - 0.000006353 50.0
HFD2_k127_1873215_3 Sulfatase-modifying factor enzyme 1 - - - 3.554e-254 815.0
HFD2_k127_1873215_30 Belongs to the 'phage' integrase family - - - 0.00002388 49.0
HFD2_k127_1873215_4 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 7.333e-223 722.0
HFD2_k127_1873215_5 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 584.0
HFD2_k127_1873215_6 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 560.0
HFD2_k127_1873215_8 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 490.0
HFD2_k127_1873215_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 458.0
HFD2_k127_188227_0 Alpha-2-Macroglobulin K06894 - - 0.0 1122.0
HFD2_k127_188227_1 beta-galactosidase activity K01190 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.23 0.0 1074.0
HFD2_k127_188227_10 alginic acid biosynthetic process - - - 5.215e-202 652.0
HFD2_k127_188227_11 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family K02100,K03444,K08138 - - 1.572e-199 634.0
HFD2_k127_188227_12 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 576.0
HFD2_k127_188227_13 penicillin-binding protein 1C K05367 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 588.0
HFD2_k127_188227_14 argininosuccinate synthase activity K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 574.0
HFD2_k127_188227_15 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 539.0
HFD2_k127_188227_16 TROVE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 521.0
HFD2_k127_188227_17 GTP binding K06942 GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 504.0
HFD2_k127_188227_18 phosphorelay signal transduction system K07713,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 476.0
HFD2_k127_188227_19 peptidase activity, acting on L-amino acid peptides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007915 481.0
HFD2_k127_188227_2 symporter activity K03307 - - 3.127e-309 954.0
HFD2_k127_188227_20 argininosuccinate lyase activity K01755,K14681 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008229 473.0
HFD2_k127_188227_21 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 451.0
HFD2_k127_188227_22 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006489 431.0
HFD2_k127_188227_23 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620,K00930 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35,2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 433.0
HFD2_k127_188227_24 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 424.0
HFD2_k127_188227_25 membrane protein, TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 403.0
HFD2_k127_188227_26 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008122 404.0
HFD2_k127_188227_27 TIGRFAM polyphosphate nucleotide phosphotransferase, PPK2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 394.0
HFD2_k127_188227_28 PFAM amino acid permease-associated region K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 403.0
HFD2_k127_188227_29 alpha,alpha-trehalase activity K01194,K03931 GO:0003674,GO:0003824,GO:0004553,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015926,GO:0016787,GO:0016798,GO:0033554,GO:0050896,GO:0051716 3.2.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 402.0
HFD2_k127_188227_3 ATP-dependent helicase K03579 - 3.6.4.13 2.169e-252 804.0
HFD2_k127_188227_30 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 370.0
HFD2_k127_188227_31 Aminotransferase class-III K00819,K00821 - 2.6.1.11,2.6.1.13,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 366.0
HFD2_k127_188227_32 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 372.0
HFD2_k127_188227_33 PFAM Alpha beta hydrolase K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 351.0
HFD2_k127_188227_34 PFAM Aminotransferase, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007657 348.0
HFD2_k127_188227_35 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 340.0
HFD2_k127_188227_36 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 333.0
HFD2_k127_188227_37 Domain of unknown function (DUF4153) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 337.0
HFD2_k127_188227_38 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 325.0
HFD2_k127_188227_39 amine dehydrogenase activity K01224 - 3.2.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009366 325.0
HFD2_k127_188227_4 Glycosyl-hydrolase 97 C-terminal, oligomerisation K01187 - 3.2.1.20 2.264e-247 780.0
HFD2_k127_188227_40 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 302.0
HFD2_k127_188227_41 PFAM Class II Aldolase and Adducin N-terminal domain K03077 - 5.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 286.0
HFD2_k127_188227_42 SMART PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002816 314.0
HFD2_k127_188227_43 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007488 267.0
HFD2_k127_188227_44 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000318 262.0
HFD2_k127_188227_45 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000007194 263.0
HFD2_k127_188227_46 Phosphoribulokinase / Uridine kinase family K00855,K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.19,2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000004779 247.0
HFD2_k127_188227_47 Asparaginase, N-terminal K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000348 241.0
HFD2_k127_188227_48 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000003367 209.0
HFD2_k127_188227_49 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000813 203.0
HFD2_k127_188227_5 PFAM Glycosyl hydrolase family 3 C terminal domain K05349 - 3.2.1.21 4.883e-245 787.0
HFD2_k127_188227_50 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000009758 216.0
HFD2_k127_188227_51 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000004503 171.0
HFD2_k127_188227_52 - - - - 0.00000000000000000000000000000000000000000001114 174.0
HFD2_k127_188227_53 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000001026 170.0
HFD2_k127_188227_54 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000000000000000002753 139.0
HFD2_k127_188227_55 2 iron, 2 sulfur cluster binding - - - 0.00000000000000000000000000000002846 130.0
HFD2_k127_188227_56 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000001806 127.0
HFD2_k127_188227_57 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000001171 132.0
HFD2_k127_188227_58 PFAM ATP-binding region ATPase domain protein K10819 - 2.7.13.3 0.0000000000000000000000000007078 123.0
HFD2_k127_188227_6 Belongs to the ribulokinase family K00853 - 2.7.1.16 1.381e-240 758.0
HFD2_k127_188227_60 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000000001229 117.0
HFD2_k127_188227_61 Subtilase family - - - 0.00000000000000000000004744 115.0
HFD2_k127_188227_62 amine dehydrogenase activity - - - 0.0000000000000005796 89.0
HFD2_k127_188227_64 positive regulation of macromolecule biosynthetic process K03973 - - 0.0000004717 55.0
HFD2_k127_188227_65 Small Multidrug Resistance protein - - - 0.0002938 48.0
HFD2_k127_188227_7 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 2.927e-234 739.0
HFD2_k127_188227_8 Glycoside hydrolase family 38 central region K01191 - 3.2.1.24 6.823e-230 751.0
HFD2_k127_188227_9 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 2.899e-225 707.0
HFD2_k127_1892829_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K11907 - - 5.955e-284 899.0
HFD2_k127_1892829_1 Type VI secretion protein, EvpB VC_A0108 family K11900 - - 2.166e-209 662.0
HFD2_k127_1892829_10 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001636 294.0
HFD2_k127_1892829_11 Type VI secretion system effector, Hcp - - - 0.0000000000000000000000000000000000000000000000000000000000000002952 224.0
HFD2_k127_1892829_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000001092 241.0
HFD2_k127_1892829_13 type VI secretion protein K11900 - - 0.0000000000000000000000000000000000000000000001132 188.0
HFD2_k127_1892829_14 type VI secretion-associated protein, VC_A0119 family K11910 - - 0.000000000000000000000000000000000000000000000979 187.0
HFD2_k127_1892829_15 Type VI secretion, TssG - - - 0.000000000000000000000000000000000000000004561 170.0
HFD2_k127_1892829_16 response regulator, receiver - - - 0.00000000000000000000000000000000000000001895 155.0
HFD2_k127_1892829_17 PAAR repeat-containing protein - - - 0.0000000000000000000000000000000000000009425 162.0
HFD2_k127_1892829_18 Radical SAM superfamily - - - 0.000000000000000000000000000000000000001277 165.0
HFD2_k127_1892829_19 type VI secretion protein K11901 - - 0.00000000000000000000000000000000000005194 148.0
HFD2_k127_1892829_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 604.0
HFD2_k127_1892829_20 - - - - 0.0000000000000000000000000000000003036 151.0
HFD2_k127_1892829_21 Type VI secretion system protein DotU K11892 - - 0.0000000000000000000000000261 124.0
HFD2_k127_1892829_22 Type VI secretion K11905 - - 0.0000000000000000000003795 101.0
HFD2_k127_1892829_23 cellulase activity K01186,K01197,K05988,K11931,K21449 - 3.2.1.11,3.2.1.18,3.2.1.35 0.000000000000000000002382 110.0
HFD2_k127_1892829_24 Uncharacterized protein conserved in bacteria (DUF2094) K11890 - - 0.00000000000000000007624 104.0
HFD2_k127_1892829_25 Outer membrane protein beta-barrel domain - - - 0.00000000000002378 83.0
HFD2_k127_1892829_26 Collagen triple helix repeat (20 copies) - - - 0.000000000001545 79.0
HFD2_k127_1892829_27 Involved in the tonB-independent uptake of proteins K08676 - - 0.000000000007335 77.0
HFD2_k127_1892829_28 histone H2A K63-linked ubiquitination - GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000169 73.0
HFD2_k127_1892829_29 Outer membrane protein beta-barrel domain - - - 0.0000001198 62.0
HFD2_k127_1892829_3 ImcF-related N-terminal domain K11891 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 539.0
HFD2_k127_1892829_30 Phage late control gene D protein (GPD) K11904 - - 0.0000005273 61.0
HFD2_k127_1892829_31 long-chain fatty acid transport protein - - - 0.000005264 58.0
HFD2_k127_1892829_32 TonB-dependent Receptor Plug Domain K02014 - - 0.00004523 53.0
HFD2_k127_1892829_34 Tricorn protease homolog K08676 - - 0.0001325 55.0
HFD2_k127_1892829_35 - - - - 0.000587 51.0
HFD2_k127_1892829_36 - - - - 0.000959 47.0
HFD2_k127_1892829_4 Type VI secretion system, TssF K11896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 481.0
HFD2_k127_1892829_5 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 421.0
HFD2_k127_1892829_6 Phage late control gene D protein (GPD) K11904 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008708 406.0
HFD2_k127_1892829_7 PFAM Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 387.0
HFD2_k127_1892829_8 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 325.0
HFD2_k127_1892829_9 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 299.0
HFD2_k127_1900207_0 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0 1512.0
HFD2_k127_1900207_10 Domain of unknown function (DUF4964) - - - 4.4e-242 769.0
HFD2_k127_1900207_11 Glycosyl hydrolases family 35 K12308 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 596.0
HFD2_k127_1900207_12 TIGRFAM cysteine desulfurase family protein, VC1184 subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 573.0
HFD2_k127_1900207_13 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 557.0
HFD2_k127_1900207_14 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009581 535.0
HFD2_k127_1900207_15 Putative glucoamylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 532.0
HFD2_k127_1900207_16 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 448.0
HFD2_k127_1900207_17 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005313 429.0
HFD2_k127_1900207_18 SIS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007797 420.0
HFD2_k127_1900207_19 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 446.0
HFD2_k127_1900207_2 TonB-dependent receptor - - - 0.0 1048.0
HFD2_k127_1900207_20 Phosphoglycerate mutase family K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 414.0
HFD2_k127_1900207_21 transmembrane transport K02025,K15771 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 410.0
HFD2_k127_1900207_22 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10562 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 420.0
HFD2_k127_1900207_23 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 395.0
HFD2_k127_1900207_24 ABC transporter substrate-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 392.0
HFD2_k127_1900207_25 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 382.0
HFD2_k127_1900207_26 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 393.0
HFD2_k127_1900207_27 glycerophosphodiester transmembrane transport K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 361.0
HFD2_k127_1900207_28 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006846 348.0
HFD2_k127_1900207_29 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 336.0
HFD2_k127_1900207_3 Sodium:solute symporter family - - - 4.831e-306 949.0
HFD2_k127_1900207_30 Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 334.0
HFD2_k127_1900207_31 Psort location Cytoplasmic, score K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006337 332.0
HFD2_k127_1900207_32 cellulose binding K00505 - 1.14.18.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 325.0
HFD2_k127_1900207_33 LacI family K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 299.0
HFD2_k127_1900207_34 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 296.0
HFD2_k127_1900207_35 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 297.0
HFD2_k127_1900207_36 Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001277 258.0
HFD2_k127_1900207_37 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002288 255.0
HFD2_k127_1900207_38 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000167 261.0
HFD2_k127_1900207_39 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000003719 249.0
HFD2_k127_1900207_4 Cellobiose phosphorylase K00702 - 2.4.1.20 5.009e-291 917.0
HFD2_k127_1900207_40 Psort location Cytoplasmic, score 8.96 - - - 0.00000000000000000000000000000000000000000000000000000000001533 219.0
HFD2_k127_1900207_41 - K07283 - - 0.00000000000000000000000000000000000000000000000000000000001857 220.0
HFD2_k127_1900207_42 peptidyl-prolyl cis-trans isomerase activity K01802,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000002259 201.0
HFD2_k127_1900207_43 - - - - 0.00000000000000000000000000000000000000000000000008797 184.0
HFD2_k127_1900207_44 water channel activity K02440,K06188 - - 0.00000000000000000000000000000000000000004243 161.0
HFD2_k127_1900207_45 stage II sporulation K07315 - 3.1.3.3 0.00000000000000000000000000000000000005858 156.0
HFD2_k127_1900207_46 YCII-related domain - - - 0.000000000000000000000000008408 112.0
HFD2_k127_1900207_47 - - - - 0.000000000000000000000000598 108.0
HFD2_k127_1900207_48 CDP-alcohol phosphatidyltransferase - - - 0.00000000000000000000005573 109.0
HFD2_k127_1900207_49 amino acid activation for nonribosomal peptide biosynthetic process K05996 - 3.4.17.18 0.000000000000000000001361 111.0
HFD2_k127_1900207_5 TonB-dependent receptor - - - 4.295e-290 916.0
HFD2_k127_1900207_50 cellulose binding K00505 - 1.14.18.1 0.00000000000000000004277 104.0
HFD2_k127_1900207_51 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000002993 83.0
HFD2_k127_1900207_52 Carbohydrate family 9 binding domain-like - - - 0.0000000000001311 79.0
HFD2_k127_1900207_6 glucan 1,4-alpha-glucosidase activity K01178 - 3.2.1.3 9.041e-281 895.0
HFD2_k127_1900207_7 - - - - 1.601e-279 895.0
HFD2_k127_1900207_8 peptidase K01278 - 3.4.14.5 3.018e-260 824.0
HFD2_k127_1900207_9 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 2.884e-246 783.0
HFD2_k127_1997943_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0016625,GO:0016903,GO:0043873,GO:0050896,GO:0055114 1.2.7.1 0.0 1681.0
HFD2_k127_1997943_1 isoleucyl-tRNA aminoacylation K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1291.0
HFD2_k127_1997943_10 ABC transporter - - - 1.685e-273 852.0
HFD2_k127_1997943_100 Belongs to the RtcB family K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 456.0
HFD2_k127_1997943_101 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 473.0
HFD2_k127_1997943_102 membrane insertase activity K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 465.0
HFD2_k127_1997943_103 phosphoglucomutase phosphomannomutase alpha beta alpha domain I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 471.0
HFD2_k127_1997943_104 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 454.0
HFD2_k127_1997943_105 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006589 450.0
HFD2_k127_1997943_106 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 456.0
HFD2_k127_1997943_107 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 467.0
HFD2_k127_1997943_108 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 450.0
HFD2_k127_1997943_109 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 458.0
HFD2_k127_1997943_11 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 4.296e-272 870.0
HFD2_k127_1997943_110 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 451.0
HFD2_k127_1997943_111 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 443.0
HFD2_k127_1997943_112 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005466 437.0
HFD2_k127_1997943_113 Peptidase, M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 448.0
HFD2_k127_1997943_114 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 437.0
HFD2_k127_1997943_115 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009705 436.0
HFD2_k127_1997943_116 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008347 428.0
HFD2_k127_1997943_117 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 426.0
HFD2_k127_1997943_118 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 443.0
HFD2_k127_1997943_119 PFAM penicillin-binding protein transpeptidase K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 441.0
HFD2_k127_1997943_12 Prolyl oligopeptidase family - - - 5.893e-268 848.0
HFD2_k127_1997943_120 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 427.0
HFD2_k127_1997943_121 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 431.0
HFD2_k127_1997943_122 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009686 418.0
HFD2_k127_1997943_123 import. Responsible for energy coupling to the transport system K02056,K10441,K10545,K10548,K10562,K17204 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 425.0
HFD2_k127_1997943_124 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 413.0
HFD2_k127_1997943_125 Transferase K02527,K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33,2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 413.0
HFD2_k127_1997943_126 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 407.0
HFD2_k127_1997943_127 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 410.0
HFD2_k127_1997943_128 major pilin protein fima - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 405.0
HFD2_k127_1997943_129 oxidative phosphorylation K00426 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 404.0
HFD2_k127_1997943_13 metallocarboxypeptidase activity K14054 - - 5.718e-260 829.0
HFD2_k127_1997943_130 purine-nucleoside phosphorylase activity K03783 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 397.0
HFD2_k127_1997943_131 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 424.0
HFD2_k127_1997943_132 PFAM peptidase T2 asparaginase 2 K01444,K13051 - 3.4.19.5,3.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 399.0
HFD2_k127_1997943_133 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 401.0
HFD2_k127_1997943_134 peptidyl-prolyl cis-trans isomerase activity K01802,K03769,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 415.0
HFD2_k127_1997943_135 Flavoprotein K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 397.0
HFD2_k127_1997943_136 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 395.0
HFD2_k127_1997943_137 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006006 388.0
HFD2_k127_1997943_138 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 391.0
HFD2_k127_1997943_139 phosphate acetyltransferase K00029,K00625,K13788 - 1.1.1.40,2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 383.0
HFD2_k127_1997943_14 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 7.267e-253 788.0
HFD2_k127_1997943_140 diaminopimelate decarboxylase activity K01586,K05366 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.1.129,3.4.16.4,4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 393.0
HFD2_k127_1997943_141 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 383.0
HFD2_k127_1997943_142 metalloendopeptidase activity K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 380.0
HFD2_k127_1997943_143 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 377.0
HFD2_k127_1997943_144 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 383.0
HFD2_k127_1997943_145 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 377.0
HFD2_k127_1997943_146 Histidine kinase K11383 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008442 387.0
HFD2_k127_1997943_147 ATP-dependent DNA helicase activity K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009717 375.0
HFD2_k127_1997943_148 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 376.0
HFD2_k127_1997943_149 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 381.0
HFD2_k127_1997943_15 Prokaryotic cytochrome b561 - - - 4.715e-251 790.0
HFD2_k127_1997943_150 proline dipeptidase activity K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 385.0
HFD2_k127_1997943_151 Deoxyribodipyrimidine photo-lyase K06876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 379.0
HFD2_k127_1997943_152 Sigma-54 interaction domain K03413,K13589 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 373.0
HFD2_k127_1997943_153 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 373.0
HFD2_k127_1997943_154 Histidine kinase K07709,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 378.0
HFD2_k127_1997943_155 Belongs to the DegT DnrJ EryC1 family K02805 - 2.6.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 369.0
HFD2_k127_1997943_156 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 383.0
HFD2_k127_1997943_157 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 370.0
HFD2_k127_1997943_158 ABC-2 family transporter protein K09696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004548 370.0
HFD2_k127_1997943_159 peptidyl-prolyl cis-trans isomerase activity K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 371.0
HFD2_k127_1997943_16 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 8.294e-249 795.0
HFD2_k127_1997943_160 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 367.0
HFD2_k127_1997943_161 Glycogen debranching enzyme, glucanotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009832 374.0
HFD2_k127_1997943_162 Glycosyl transferase family 21 K19003 - 2.4.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 366.0
HFD2_k127_1997943_163 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 359.0
HFD2_k127_1997943_164 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 361.0
HFD2_k127_1997943_165 PFAM Integral membrane protein TerC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 351.0
HFD2_k127_1997943_166 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 362.0
HFD2_k127_1997943_167 N-Acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006572 361.0
HFD2_k127_1997943_168 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 353.0
HFD2_k127_1997943_169 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 364.0
HFD2_k127_1997943_17 (ABC) transporter K06147,K18890 - - 3.025e-247 776.0
HFD2_k127_1997943_170 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007641 346.0
HFD2_k127_1997943_171 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 343.0
HFD2_k127_1997943_172 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 351.0
HFD2_k127_1997943_173 PFAM Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 341.0
HFD2_k127_1997943_174 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 342.0
HFD2_k127_1997943_175 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 336.0
HFD2_k127_1997943_176 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 339.0
HFD2_k127_1997943_177 Belongs to the short-chain dehydrogenases reductases (SDR) family K05886 - 1.1.1.276 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 330.0
HFD2_k127_1997943_178 ATPases associated with a variety of cellular activities K09697 - 3.6.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 326.0
HFD2_k127_1997943_179 peptidoglycan glycosyltransferase activity K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 333.0
HFD2_k127_1997943_18 GTP-binding protein TypA K06207 - - 1.064e-246 777.0
HFD2_k127_1997943_180 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 336.0
HFD2_k127_1997943_181 Belongs to the 'phage' integrase family K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 324.0
HFD2_k127_1997943_182 Belongs to the glycosyl hydrolase family 6 K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 321.0
HFD2_k127_1997943_183 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008546 329.0
HFD2_k127_1997943_184 ADP-L-glycero-beta-D-manno-heptose biosynthetic process K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 325.0
HFD2_k127_1997943_185 4 iron, 4 sulfur cluster binding K04014,K08353,K08358,K16293 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044464,GO:0055114,GO:0098809 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 325.0
HFD2_k127_1997943_186 Bacterial membrane protein, YfhO - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007114 341.0
HFD2_k127_1997943_187 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009937 319.0
HFD2_k127_1997943_188 denitrification pathway - GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0019645,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007068 328.0
HFD2_k127_1997943_189 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008857 327.0
HFD2_k127_1997943_19 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 4.086e-242 768.0
HFD2_k127_1997943_190 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 327.0
HFD2_k127_1997943_191 PPIC-type PPIASE domain K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 333.0
HFD2_k127_1997943_192 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 330.0
HFD2_k127_1997943_193 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 313.0
HFD2_k127_1997943_194 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 323.0
HFD2_k127_1997943_195 metalloendopeptidase activity K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 315.0
HFD2_k127_1997943_196 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 308.0
HFD2_k127_1997943_197 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008689 339.0
HFD2_k127_1997943_198 PFAM asparagine synthase K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008836 306.0
HFD2_k127_1997943_199 PhoQ Sensor K01768,K04769,K10914 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009249 320.0
HFD2_k127_1997943_2 DNA topoisomerase II activity K02469 - 5.99.1.3 0.0 1176.0
HFD2_k127_1997943_20 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 6.813e-242 773.0
HFD2_k127_1997943_200 Responsible for synthesis of pseudouridine from uracil K06177,K06180 GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009868 312.0
HFD2_k127_1997943_201 SMART PAS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 327.0
HFD2_k127_1997943_202 carboxypeptidase activity K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 307.0
HFD2_k127_1997943_203 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 299.0
HFD2_k127_1997943_204 Periplasmic binding proteins and sugar binding domain of LacI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 306.0
HFD2_k127_1997943_205 Bacterial extracellular solute-binding protein, family 7 K11688,K21395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 318.0
HFD2_k127_1997943_206 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 322.0
HFD2_k127_1997943_207 transferase activity, transferring glycosyl groups K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 308.0
HFD2_k127_1997943_208 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K05827,K05844 - 6.3.2.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 299.0
HFD2_k127_1997943_209 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007254 295.0
HFD2_k127_1997943_21 amine dehydrogenase activity - - - 1.883e-240 777.0
HFD2_k127_1997943_210 rRNA (adenine-C2-)-methyltransferase activity K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 302.0
HFD2_k127_1997943_211 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K06898,K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 320.0
HFD2_k127_1997943_212 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 300.0
HFD2_k127_1997943_213 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 297.0
HFD2_k127_1997943_214 electron transfer activity K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 299.0
HFD2_k127_1997943_215 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 304.0
HFD2_k127_1997943_216 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004501 298.0
HFD2_k127_1997943_217 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009584 293.0
HFD2_k127_1997943_218 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 297.0
HFD2_k127_1997943_219 Cytochrome c554 and c-prime K03620 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 306.0
HFD2_k127_1997943_22 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 1.353e-237 759.0
HFD2_k127_1997943_220 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006956 285.0
HFD2_k127_1997943_221 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002645 290.0
HFD2_k127_1997943_222 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001997 281.0
HFD2_k127_1997943_223 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004596 280.0
HFD2_k127_1997943_224 ergosterol biosynthetic process K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004983 285.0
HFD2_k127_1997943_225 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006715 286.0
HFD2_k127_1997943_226 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004287 297.0
HFD2_k127_1997943_227 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000451 289.0
HFD2_k127_1997943_228 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001121 273.0
HFD2_k127_1997943_229 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002941 276.0
HFD2_k127_1997943_23 CTP synthase activity K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 2.346e-234 736.0
HFD2_k127_1997943_230 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000301 272.0
HFD2_k127_1997943_231 - K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004349 264.0
HFD2_k127_1997943_232 Squalene/phytoene synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007996 270.0
HFD2_k127_1997943_233 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001192 274.0
HFD2_k127_1997943_234 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000001655 274.0
HFD2_k127_1997943_235 - K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005436 267.0
HFD2_k127_1997943_236 PFAM Uncharacterised BCR, COG1649 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000567 280.0
HFD2_k127_1997943_237 DNA-templated transcription, initiation K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001011 262.0
HFD2_k127_1997943_238 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000212 270.0
HFD2_k127_1997943_239 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000122 262.0
HFD2_k127_1997943_24 formate dehydrogenase - - - 1.142e-230 740.0
HFD2_k127_1997943_240 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001358 264.0
HFD2_k127_1997943_241 deaminated base DNA N-glycosylase activity K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000004054 262.0
HFD2_k127_1997943_242 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009309 279.0
HFD2_k127_1997943_243 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000001144 266.0
HFD2_k127_1997943_244 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001315 261.0
HFD2_k127_1997943_245 ATP binding cassette transporter ABC protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001366 261.0
HFD2_k127_1997943_246 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K00406,K01011,K07112 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000002544 259.0
HFD2_k127_1997943_247 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002826 266.0
HFD2_k127_1997943_248 Uncharacterized protein conserved in bacteria (DUF2334) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006765 281.0
HFD2_k127_1997943_249 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000008749 264.0
HFD2_k127_1997943_25 H( )-stimulated, divalent metal cation uptake system K03322 - - 1.631e-229 727.0
HFD2_k127_1997943_250 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000191 263.0
HFD2_k127_1997943_251 tRNA pseudouridine synthase activity K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000003715 254.0
HFD2_k127_1997943_252 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003893 261.0
HFD2_k127_1997943_253 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000001933 253.0
HFD2_k127_1997943_254 PFAM YicC domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002067 258.0
HFD2_k127_1997943_255 Glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003899 250.0
HFD2_k127_1997943_256 phosphatidate phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000504 256.0
HFD2_k127_1997943_257 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000007089 249.0
HFD2_k127_1997943_258 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000009307 244.0
HFD2_k127_1997943_259 PFAM Appr-1-p processing - - - 0.00000000000000000000000000000000000000000000000000000000000000000002161 237.0
HFD2_k127_1997943_26 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 7.805e-227 729.0
HFD2_k127_1997943_260 deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002314 254.0
HFD2_k127_1997943_261 FES K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000005413 242.0
HFD2_k127_1997943_262 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760,K00939,K15780 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,2.7.4.3,6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000001029 235.0
HFD2_k127_1997943_263 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000001325 243.0
HFD2_k127_1997943_264 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000000000000000000000000000000000000000000000001325 231.0
HFD2_k127_1997943_265 PFAM Uncharacterised BCR, COG1649 - - - 0.000000000000000000000000000000000000000000000000000000000000000002601 243.0
HFD2_k127_1997943_266 peptidyl-prolyl cis-trans isomerase activity K03545 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000004315 247.0
HFD2_k127_1997943_267 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000007781 233.0
HFD2_k127_1997943_268 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000003387 232.0
HFD2_k127_1997943_269 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000004969 233.0
HFD2_k127_1997943_27 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 8.06e-224 705.0
HFD2_k127_1997943_270 COG1121 ABC-type Mn Zn transport systems ATPase component K11607,K11710 - - 0.00000000000000000000000000000000000000000000000000000000000000005859 231.0
HFD2_k127_1997943_271 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000006542 227.0
HFD2_k127_1997943_272 Zinc-uptake complex component A periplasmic K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000008725 242.0
HFD2_k127_1997943_273 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000925 227.0
HFD2_k127_1997943_274 isomerase activity K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000001677 228.0
HFD2_k127_1997943_275 - - - - 0.00000000000000000000000000000000000000000000000000000000000000214 229.0
HFD2_k127_1997943_277 - K01992,K19341 - - 0.000000000000000000000000000000000000000000000000000000000000004671 229.0
HFD2_k127_1997943_278 Bacterial membrane protein YfhO - - - 0.00000000000000000000000000000000000000000000000000000000000005731 239.0
HFD2_k127_1997943_279 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000006237 228.0
HFD2_k127_1997943_28 transferase activity, transferring glycosyl groups K00694,K00786 - 2.4.1.12 1.303e-219 691.0
HFD2_k127_1997943_280 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000001692 219.0
HFD2_k127_1997943_281 RNA pseudouridylate synthase K06181 - 5.4.99.20 0.0000000000000000000000000000000000000000000000000000000000005994 217.0
HFD2_k127_1997943_282 - - - - 0.000000000000000000000000000000000000000000000000000000000004594 231.0
HFD2_k127_1997943_283 dolichyl monophosphate biosynthetic process K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000747 215.0
HFD2_k127_1997943_284 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.000000000000000000000000000000000000000000000000000000000008156 222.0
HFD2_k127_1997943_285 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000000001123 212.0
HFD2_k127_1997943_286 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000005893 219.0
HFD2_k127_1997943_287 Glycosyl transferase, family 9 K02843 - - 0.00000000000000000000000000000000000000000000000000000000009238 217.0
HFD2_k127_1997943_288 acetylesterase activity - - - 0.0000000000000000000000000000000000000000000000000000000007279 213.0
HFD2_k127_1997943_289 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000001258 218.0
HFD2_k127_1997943_29 Fumarase C C-terminus K01744 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008797,GO:0009058,GO:0009066,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0019222,GO:0019752,GO:0030162,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1903317,GO:1903319 4.3.1.1 4.057e-219 689.0
HFD2_k127_1997943_290 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000005869 221.0
HFD2_k127_1997943_291 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000000000000000000001244 212.0
HFD2_k127_1997943_292 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000002251 210.0
HFD2_k127_1997943_293 FAD dependent oxidoreductase K00514 - 1.3.5.6 0.00000000000000000000000000000000000000000000000000000002819 219.0
HFD2_k127_1997943_294 Dihydrouridine synthase (Dus) K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000004337 205.0
HFD2_k127_1997943_295 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000002388 211.0
HFD2_k127_1997943_296 PFAM UvrB UvrC protein K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000005665 199.0
HFD2_k127_1997943_297 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000968 201.0
HFD2_k127_1997943_298 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000003827 195.0
HFD2_k127_1997943_299 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000006691 192.0
HFD2_k127_1997943_3 molybdopterin cofactor binding K08352 - 1.8.5.5 0.0 1140.0
HFD2_k127_1997943_30 aerobic electron transport chain K00425 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 2.458e-217 683.0
HFD2_k127_1997943_300 Membrane - - - 0.0000000000000000000000000000000000000000000000000007016 200.0
HFD2_k127_1997943_301 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000008187 188.0
HFD2_k127_1997943_302 Peptidase family M28 K05994 - 3.4.11.10 0.000000000000000000000000000000000000000000000000001191 201.0
HFD2_k127_1997943_303 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000121 191.0
HFD2_k127_1997943_304 Protein of unknown function (DUF2851) - - - 0.00000000000000000000000000000000000000000000000009998 195.0
HFD2_k127_1997943_305 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family - - - 0.0000000000000000000000000000000000000000000000001319 193.0
HFD2_k127_1997943_306 Glycosyl transferase, family 9 K02841,K02843,K02847,K02849,K21003 - - 0.0000000000000000000000000000000000000000000000001491 190.0
HFD2_k127_1997943_307 MraZ protein, putative antitoxin-like K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000000000000000000000000001618 180.0
HFD2_k127_1997943_308 guanylate kinase activity K00942,K01591 GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8,4.1.1.23 0.0000000000000000000000000000000000000000000000003136 189.0
HFD2_k127_1997943_309 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000002006 191.0
HFD2_k127_1997943_31 homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 1.95e-214 682.0
HFD2_k127_1997943_310 HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.000000000000000000000000000000000000000000000007542 179.0
HFD2_k127_1997943_311 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000007854 181.0
HFD2_k127_1997943_312 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000003638 177.0
HFD2_k127_1997943_315 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000935 180.0
HFD2_k127_1997943_316 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000000000000000000000000000136 176.0
HFD2_k127_1997943_317 Acyl-transferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000005881 177.0
HFD2_k127_1997943_318 Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000000001581 171.0
HFD2_k127_1997943_319 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.00000000000000000000000000000000000000000001602 167.0
HFD2_k127_1997943_32 lipopolysaccharide transport - - - 5.312e-214 694.0
HFD2_k127_1997943_320 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000001959 166.0
HFD2_k127_1997943_321 nucleotide phosphatase activity, acting on free nucleotides K00943,K02013,K02017,K03574,K03752,K06928 - 2.7.4.9,2.7.7.77,3.6.1.15,3.6.1.55,3.6.3.29,3.6.3.34 0.00000000000000000000000000000000000000000007399 180.0
HFD2_k127_1997943_322 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000000000000000000002431 172.0
HFD2_k127_1997943_323 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000004769 175.0
HFD2_k127_1997943_324 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000002963 164.0
HFD2_k127_1997943_325 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000007201 162.0
HFD2_k127_1997943_326 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000001048 156.0
HFD2_k127_1997943_327 phospholipase K06999 - - 0.00000000000000000000000000000000000000001662 162.0
HFD2_k127_1997943_328 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000002274 164.0
HFD2_k127_1997943_329 Acetyltransferase (GNAT) domain K02348 - - 0.00000000000000000000000000000000000000006712 159.0
HFD2_k127_1997943_33 L-asparaginase K01424 - 3.5.1.1 6.983e-214 686.0
HFD2_k127_1997943_330 Putative zincin peptidase - - - 0.00000000000000000000000000000000000000009182 158.0
HFD2_k127_1997943_331 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.00000000000000000000000000000000000000009771 159.0
HFD2_k127_1997943_332 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000004215 169.0
HFD2_k127_1997943_333 ABC-type Mn2 Zn2 transport systems permease components K02075,K09816 - - 0.000000000000000000000000000000000000000534 160.0
HFD2_k127_1997943_334 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K19591,K22491 - - 0.0000000000000000000000000000000000000008693 152.0
HFD2_k127_1997943_335 DNA-templated transcription, initiation K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.000000000000000000000000000000000000004332 153.0
HFD2_k127_1997943_336 NUDIX domain - - - 0.000000000000000000000000000000000000004799 157.0
HFD2_k127_1997943_338 Outer membrane transport energization protein ExbD - - - 0.00000000000000000000000000000000000001009 149.0
HFD2_k127_1997943_339 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000001303 151.0
HFD2_k127_1997943_34 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972,K10754 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 9.377e-214 695.0
HFD2_k127_1997943_340 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000002232 157.0
HFD2_k127_1997943_341 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000002394 151.0
HFD2_k127_1997943_342 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K13640 - - 0.0000000000000000000000000000000000002506 145.0
HFD2_k127_1997943_343 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000026 152.0
HFD2_k127_1997943_344 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000001337 145.0
HFD2_k127_1997943_345 - - - - 0.000000000000000000000000000000000001772 154.0
HFD2_k127_1997943_346 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.00000000000000000000000000000000000495 142.0
HFD2_k127_1997943_347 HAD-superfamily hydrolase, subfamily IA, variant 1 K07025 - - 0.000000000000000000000000000000000009006 148.0
HFD2_k127_1997943_349 PFAM Rhomboid family - - - 0.00000000000000000000000000000000001757 146.0
HFD2_k127_1997943_35 Phosphofructokinase K21071 - 2.7.1.11,2.7.1.90 2.219e-213 667.0
HFD2_k127_1997943_350 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.00000000000000000000000000000000002008 141.0
HFD2_k127_1997943_351 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000002389 143.0
HFD2_k127_1997943_352 PFAM Biopolymer transport protein ExbD TolR - - - 0.0000000000000000000000000000000000402 139.0
HFD2_k127_1997943_353 YbbR-like protein - GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - 0.0000000000000000000000000000000001559 146.0
HFD2_k127_1997943_354 - - - - 0.0000000000000000000000000000000007647 139.0
HFD2_k127_1997943_355 Protease prsW family - - - 0.000000000000000000000000000000001908 142.0
HFD2_k127_1997943_356 - - - - 0.000000000000000000000000000000001987 135.0
HFD2_k127_1997943_357 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000003094 139.0
HFD2_k127_1997943_358 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K07081,K11782,K11784 - 1.21.98.1,4.2.1.151 0.000000000000000000000000000000006662 139.0
HFD2_k127_1997943_359 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.000000000000000000000000000000007389 141.0
HFD2_k127_1997943_36 lactate metabolic process - - - 6.112e-212 676.0
HFD2_k127_1997943_360 Methionine biosynthesis protein MetW K18827 - 2.1.1.294,2.7.1.181 0.00000000000000000000000000000001209 137.0
HFD2_k127_1997943_361 amine dehydrogenase activity K21449 - - 0.00000000000000000000000000000001559 134.0
HFD2_k127_1997943_362 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000002152 129.0
HFD2_k127_1997943_363 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000003233 135.0
HFD2_k127_1997943_364 pectinesterase activity - - - 0.0000000000000000000000000000000745 134.0
HFD2_k127_1997943_365 Peptidase family M23 - - - 0.0000000000000000000000000000001485 135.0
HFD2_k127_1997943_366 zinc ion binding K06204 - - 0.0000000000000000000000000000001841 130.0
HFD2_k127_1997943_367 Response regulator receiver domain - - - 0.0000000000000000000000000000002574 143.0
HFD2_k127_1997943_368 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K18456 - 3.5.4.28,3.5.4.31,3.5.4.32 0.0000000000000000000000000000002829 140.0
HFD2_k127_1997943_369 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.0000000000000000000000000000004057 130.0
HFD2_k127_1997943_37 Prolyl oligopeptidase family - - - 5.06e-208 668.0
HFD2_k127_1997943_370 Glycosyl transferase 4-like - - - 0.0000000000000000000000000000004744 138.0
HFD2_k127_1997943_371 TIGRFAM TonB family protein K03832 - - 0.0000000000000000000000000000005998 133.0
HFD2_k127_1997943_372 DinB superfamily K07552 - - 0.000000000000000000000000000001977 128.0
HFD2_k127_1997943_373 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000239 125.0
HFD2_k127_1997943_374 DivIVA protein K04074 - - 0.000000000000000000000000000004916 127.0
HFD2_k127_1997943_375 PBP superfamily domain K02040 - - 0.00000000000000000000000000003536 135.0
HFD2_k127_1997943_376 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000003917 132.0
HFD2_k127_1997943_377 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000000000584 119.0
HFD2_k127_1997943_378 regulatory protein, arsR K21903 - - 0.00000000000000000000000000005979 123.0
HFD2_k127_1997943_379 Protein of unknown function (DUF1579) - - - 0.00000000000000000000000000008493 125.0
HFD2_k127_1997943_38 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.553e-207 663.0
HFD2_k127_1997943_380 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000046 121.0
HFD2_k127_1997943_381 phosphate-selective porin O and P - - - 0.0000000000000000000000000006464 128.0
HFD2_k127_1997943_382 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000001461 116.0
HFD2_k127_1997943_383 Protein of unknown function (DUF3298) - - - 0.000000000000000000000000002093 123.0
HFD2_k127_1997943_384 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000004372 119.0
HFD2_k127_1997943_385 regulation of translation K03530 - - 0.00000000000000000000000002271 111.0
HFD2_k127_1997943_386 PAP2 superfamily - - - 0.0000000000000000000000000328 118.0
HFD2_k127_1997943_387 holo-[acyl-carrier-protein] synthase activity K00950,K00997,K01207,K01775,K06133,K06925,K18014 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 2.7.6.3,2.7.8.7,3.2.1.52,4.3.1.14,5.1.1.1 0.00000000000000000000000004322 121.0
HFD2_k127_1997943_388 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000006811 115.0
HFD2_k127_1997943_389 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000144 109.0
HFD2_k127_1997943_39 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.313e-205 662.0
HFD2_k127_1997943_390 sequence-specific DNA binding - - - 0.0000000000000000000000008661 115.0
HFD2_k127_1997943_391 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000009538 111.0
HFD2_k127_1997943_392 peptidoglycan binding K03749,K07114,K08300,K09859 - 3.1.26.12 0.000000000000000000000002187 112.0
HFD2_k127_1997943_393 sigma factor antagonist activity K04757,K06379,K08282 - 2.7.11.1 0.000000000000000000000003938 106.0
HFD2_k127_1997943_395 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.000000000000000000000008585 109.0
HFD2_k127_1997943_396 extracellular matrix structural constituent - - - 0.000000000000000000000045 116.0
HFD2_k127_1997943_397 - - - - 0.0000000000000000000000722 106.0
HFD2_k127_1997943_398 CoA binding domain - - - 0.00000000000000000000007856 107.0
HFD2_k127_1997943_399 Cysteine methyltransferase K07443 - - 0.00000000000000000000009878 102.0
HFD2_k127_1997943_4 membrane organization K03641,K07277 - - 0.0 1030.0
HFD2_k127_1997943_40 UDP-N-acetylmuramate-L-alanine ligase activity K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 9.144e-203 646.0
HFD2_k127_1997943_400 ATP hydrolysis coupled proton transport K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000002508 98.0
HFD2_k127_1997943_401 FecR protein - - - 0.0000000000000000000003669 105.0
HFD2_k127_1997943_402 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000001009 100.0
HFD2_k127_1997943_403 phosphorelay signal transduction system - - - 0.000000000000000000002399 99.0
HFD2_k127_1997943_404 - - - - 0.00000000000000000000538 94.0
HFD2_k127_1997943_405 - - - - 0.000000000000000000009956 107.0
HFD2_k127_1997943_406 Subtilase family - - - 0.00000000000000000001072 107.0
HFD2_k127_1997943_407 - - - - 0.00000000000000000001152 96.0
HFD2_k127_1997943_408 AMP binding - - - 0.0000000000000000001562 96.0
HFD2_k127_1997943_409 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000222 92.0
HFD2_k127_1997943_41 Belongs to the citrate synthase family K01647 - 2.3.3.1 9.561e-203 646.0
HFD2_k127_1997943_410 cellulose binding - - - 0.0000000000000000002876 103.0
HFD2_k127_1997943_411 - - - - 0.0000000000000000009177 96.0
HFD2_k127_1997943_412 - - - - 0.000000000000000002709 95.0
HFD2_k127_1997943_413 Belongs to the UPF0109 family K06960 - - 0.000000000000000005425 85.0
HFD2_k127_1997943_416 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000001761 89.0
HFD2_k127_1997943_417 antisigma factor binding K04749 - - 0.00000000000000002369 87.0
HFD2_k127_1997943_419 - - - - 0.00000000000000008143 91.0
HFD2_k127_1997943_42 phosphopyruvate hydratase activity K01689 GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 7.077e-202 638.0
HFD2_k127_1997943_420 antisigma factor binding K04749,K06378 - - 0.0000000000000002752 83.0
HFD2_k127_1997943_421 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000004062 82.0
HFD2_k127_1997943_422 Predicted membrane protein (DUF2085) - - - 0.0000000000000004438 86.0
HFD2_k127_1997943_423 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000007538 78.0
HFD2_k127_1997943_424 Planctomycete cytochrome C - - - 0.000000000000001005 82.0
HFD2_k127_1997943_425 - - - - 0.000000000000001051 89.0
HFD2_k127_1997943_426 - - - - 0.000000000000001895 88.0
HFD2_k127_1997943_427 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000001957 92.0
HFD2_k127_1997943_428 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00847,K00852,K18478 - 2.7.1.15,2.7.1.184,2.7.1.4 0.000000000000002171 87.0
HFD2_k127_1997943_43 metal-dependent hydrolase with the TIM-barrel fold - - - 7.576e-201 639.0
HFD2_k127_1997943_430 membrane - - - 0.00000000000002371 85.0
HFD2_k127_1997943_431 - - - - 0.00000000000002623 84.0
HFD2_k127_1997943_432 rod shape-determining protein MreD K03571 - - 0.00000000000005671 79.0
HFD2_k127_1997943_433 ABC-2 type transporter K01992 - - 0.00000000000008981 83.0
HFD2_k127_1997943_434 Outer membrane lipoprotein - - - 0.0000000000001053 80.0
HFD2_k127_1997943_435 - - - - 0.0000000000002575 81.0
HFD2_k127_1997943_436 nitrogen fixation - - - 0.0000000000002731 76.0
HFD2_k127_1997943_438 SpoIIE domain protein K07315 - 3.1.3.3 0.000000000001529 73.0
HFD2_k127_1997943_439 - - - - 0.000000000002762 72.0
HFD2_k127_1997943_44 ABC transporter K06158 - - 1.065e-200 646.0
HFD2_k127_1997943_440 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.00000000001718 75.0
HFD2_k127_1997943_442 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000267 75.0
HFD2_k127_1997943_443 mercury ion transmembrane transporter activity K07213 - - 0.00000000002853 67.0
HFD2_k127_1997943_444 Domain of unknown function (DUF4203) - - - 0.00000000003119 73.0
HFD2_k127_1997943_445 Tetratricopeptide repeat - - - 0.000000000032 76.0
HFD2_k127_1997943_446 Tetratricopeptide repeat domain protein - - - 0.00000000007621 76.0
HFD2_k127_1997943_447 - - - - 0.0000000002473 66.0
HFD2_k127_1997943_448 Protein of unknown function (DUF721) - - - 0.0000000002917 69.0
HFD2_k127_1997943_449 - - - - 0.0000000004976 68.0
HFD2_k127_1997943_45 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 5.096e-200 651.0
HFD2_k127_1997943_450 PPIC-type PPIASE domain - - - 0.00000002065 65.0
HFD2_k127_1997943_451 STAS domain - - - 0.00000004278 58.0
HFD2_k127_1997943_452 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0000001336 58.0
HFD2_k127_1997943_455 transferase activity, transferring glycosyl groups - - - 0.0000002904 60.0
HFD2_k127_1997943_456 chaperone-mediated protein folding K20543 - - 0.000001468 58.0
HFD2_k127_1997943_457 cell cycle K05589,K12065,K13052 - - 0.000001735 54.0
HFD2_k127_1997943_458 Outer membrane protein beta-barrel domain - - - 0.000001842 59.0
HFD2_k127_1997943_459 Putative zinc-finger - GO:0005575,GO:0016020 - 0.00001331 56.0
HFD2_k127_1997943_46 (ABC) transporter K06147,K18889 - - 9.062e-197 629.0
HFD2_k127_1997943_460 ribonuclease P activity K03536,K08998 GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.00002156 51.0
HFD2_k127_1997943_461 - - - - 0.0000233 55.0
HFD2_k127_1997943_463 Protein of unknown function (DUF1572) - - - 0.00006484 54.0
HFD2_k127_1997943_465 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K22110 - - 0.000105 50.0
HFD2_k127_1997943_466 Yip1 domain - - - 0.0001208 53.0
HFD2_k127_1997943_469 - - - - 0.0001875 53.0
HFD2_k127_1997943_47 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 2.562e-196 641.0
HFD2_k127_1997943_470 Belongs to the anti-sigma-factor antagonist family K04749 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0002915 49.0
HFD2_k127_1997943_471 Cell division protein FtsQ K03589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - 0.0003947 51.0
HFD2_k127_1997943_473 sister chromatid segregation - - - 0.0007259 45.0
HFD2_k127_1997943_48 Sigma-54 interaction domain K03405 - 6.6.1.1 6.822e-196 625.0
HFD2_k127_1997943_49 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 8.886e-196 629.0
HFD2_k127_1997943_5 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 1.032e-318 992.0
HFD2_k127_1997943_50 - - - - 9.601e-195 616.0
HFD2_k127_1997943_51 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 3.521e-194 617.0
HFD2_k127_1997943_52 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 640.0
HFD2_k127_1997943_53 oligopeptide transport K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 603.0
HFD2_k127_1997943_54 unfolded protein binding K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 587.0
HFD2_k127_1997943_55 Oligopeptidase F K08602 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 592.0
HFD2_k127_1997943_56 Domain of unknown function (DUF4921) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 579.0
HFD2_k127_1997943_57 antibiotic biosynthetic process K01434,K07116 - 3.5.1.11,3.5.1.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 597.0
HFD2_k127_1997943_58 Peptidase family M49 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 583.0
HFD2_k127_1997943_59 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 589.0
HFD2_k127_1997943_6 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 5.257e-297 946.0
HFD2_k127_1997943_60 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 575.0
HFD2_k127_1997943_61 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573,K12585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 588.0
HFD2_k127_1997943_62 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 576.0
HFD2_k127_1997943_63 Heavy metal translocating P-type atpase K01534 - 3.6.3.3,3.6.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 578.0
HFD2_k127_1997943_64 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 559.0
HFD2_k127_1997943_65 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 564.0
HFD2_k127_1997943_66 phosphorelay signal transduction system K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005069 558.0
HFD2_k127_1997943_67 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 547.0
HFD2_k127_1997943_68 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 556.0
HFD2_k127_1997943_69 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 551.0
HFD2_k127_1997943_7 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 7.407e-292 917.0
HFD2_k127_1997943_70 Chase2 domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006902 561.0
HFD2_k127_1997943_71 Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 540.0
HFD2_k127_1997943_72 7TM receptor with intracellular HD hydrolase K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 554.0
HFD2_k127_1997943_73 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 539.0
HFD2_k127_1997943_74 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 531.0
HFD2_k127_1997943_75 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 531.0
HFD2_k127_1997943_76 helicase superfamily c-terminal domain K03732 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 530.0
HFD2_k127_1997943_77 Sigma-54 interaction domain K11384 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 531.0
HFD2_k127_1997943_78 UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity K00790 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 520.0
HFD2_k127_1997943_79 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 521.0
HFD2_k127_1997943_8 DNA topoisomerase II activity K02470 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 3.133e-283 889.0
HFD2_k127_1997943_80 Alpha-amylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 515.0
HFD2_k127_1997943_81 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 509.0
HFD2_k127_1997943_82 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 507.0
HFD2_k127_1997943_83 nucleic acid phosphodiester bond hydrolysis K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006655 505.0
HFD2_k127_1997943_84 GxGYxYP putative glycoside hydrolase C-terminal domain K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 511.0
HFD2_k127_1997943_85 HELICc2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 507.0
HFD2_k127_1997943_86 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 490.0
HFD2_k127_1997943_87 aminopeptidase K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 511.0
HFD2_k127_1997943_88 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 498.0
HFD2_k127_1997943_89 PFAM AAA ATPase central domain protein K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 490.0
HFD2_k127_1997943_9 GxGYxYP putative glycoside hydrolase C-terminal domain K03088 - - 6.505e-281 881.0
HFD2_k127_1997943_90 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 488.0
HFD2_k127_1997943_91 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 482.0
HFD2_k127_1997943_92 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 488.0
HFD2_k127_1997943_93 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 462.0
HFD2_k127_1997943_94 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 468.0
HFD2_k127_1997943_95 oligopeptide transport K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 466.0
HFD2_k127_1997943_96 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 467.0
HFD2_k127_1997943_97 GatB/GatE catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 475.0
HFD2_k127_1997943_98 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 456.0
HFD2_k127_1997943_99 Associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 455.0
HFD2_k127_2008228_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 603.0
HFD2_k127_2008228_1 MFS_1 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 485.0
HFD2_k127_2008228_2 PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007817 426.0
HFD2_k127_2008228_3 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008777 259.0
HFD2_k127_2008228_4 deoxyhypusine monooxygenase activity - - - 0.000000000002248 78.0
HFD2_k127_2008228_5 Cytochrome c - - - 0.00001428 57.0
HFD2_k127_202139_0 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 8.307e-272 849.0
HFD2_k127_202139_1 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 1.547e-222 695.0
HFD2_k127_202139_10 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K09007,K13940,K17488 - 2.7.6.3,3.5.4.16,3.5.4.39,4.1.2.25 0.00000000000000000000000000000000000004365 150.0
HFD2_k127_202139_11 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000004846 131.0
HFD2_k127_202139_12 ATP synthesis coupled electron transport K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000003434 130.0
HFD2_k127_202139_13 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000001344 124.0
HFD2_k127_202139_2 glutamate-tRNA ligase activity K01886 GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 1.184e-211 666.0
HFD2_k127_202139_3 quinolinate synthetase A activity K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 472.0
HFD2_k127_202139_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000807 459.0
HFD2_k127_202139_5 pfam abc K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006601 296.0
HFD2_k127_202139_6 transmembrane transport K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009596 302.0
HFD2_k127_202139_7 Deoxynucleoside kinase K15518 - 2.7.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000006582 267.0
HFD2_k127_202139_8 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02841,K02843,K12982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000186 249.0
HFD2_k127_202139_9 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000002203 216.0
HFD2_k127_2153083_0 - - - - 0.0 1286.0
HFD2_k127_2153083_1 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.0 1163.0
HFD2_k127_2153083_10 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 593.0
HFD2_k127_2153083_11 fibronectin type III domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 602.0
HFD2_k127_2153083_12 Belongs to the glycosyl hydrolase 31 family K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 608.0
HFD2_k127_2153083_13 Major facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 579.0
HFD2_k127_2153083_14 Proline racemase K12658 - 5.1.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 509.0
HFD2_k127_2153083_15 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 508.0
HFD2_k127_2153083_16 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 499.0
HFD2_k127_2153083_17 Mandelate racemase muconate lactonizing enzyme K01776,K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20,5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008602 482.0
HFD2_k127_2153083_18 Proline racemase K01777 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016855,GO:0018112,GO:0019752,GO:0036361,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047661,GO:0050346,GO:0071704,GO:1901564 5.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 478.0
HFD2_k127_2153083_19 Metallopeptidase family M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 477.0
HFD2_k127_2153083_2 transport - - - 0.0 1079.0
HFD2_k127_2153083_20 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 417.0
HFD2_k127_2153083_21 COGs COG4299 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 392.0
HFD2_k127_2153083_22 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 390.0
HFD2_k127_2153083_23 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 385.0
HFD2_k127_2153083_24 metalloendopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009153 366.0
HFD2_k127_2153083_25 Belongs to the DapA family K01714,K21062 - 3.5.4.22,4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 357.0
HFD2_k127_2153083_26 WD domain, G-beta repeat protein K20478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 362.0
HFD2_k127_2153083_27 N-Acetylmuramoyl-L-alanine amidase K01176,K01448,K06385 - 3.2.1.1,3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 361.0
HFD2_k127_2153083_28 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 334.0
HFD2_k127_2153083_29 Serine carboxypeptidase S28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008857 323.0
HFD2_k127_2153083_3 TonB-dependent receptor - - - 0.0 1078.0
HFD2_k127_2153083_30 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 319.0
HFD2_k127_2153083_31 Cell wall-associated hydrolase (invasion-associated protein) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007403 317.0
HFD2_k127_2153083_32 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000091 303.0
HFD2_k127_2153083_33 regulation of single-species biofilm formation - GO:0008150,GO:0043900,GO:0050789,GO:0050794,GO:0065007,GO:1900190 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 292.0
HFD2_k127_2153083_34 UDPglucose--hexose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 291.0
HFD2_k127_2153083_35 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001827 272.0
HFD2_k127_2153083_36 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001246 267.0
HFD2_k127_2153083_37 N-Acetylmuramoyl-L-alanine amidase K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000001041 248.0
HFD2_k127_2153083_38 FCD - - - 0.00000000000000000000000000000000000000000000000000000000008592 211.0
HFD2_k127_2153083_39 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000000000000000000000000000008812 224.0
HFD2_k127_2153083_4 glucosamine-6-phosphate deaminase activity K01057,K02564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.1.1.31,3.5.99.6 2.394e-285 899.0
HFD2_k127_2153083_40 protein secretion - - - 0.00000000000000000000000000000000000000000000000000000001073 222.0
HFD2_k127_2153083_41 beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000004445 214.0
HFD2_k127_2153083_42 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000000000000000000002375 195.0
HFD2_k127_2153083_43 acetyltransferase K22441 - 2.3.1.57 0.00000000000000000000000000000000000000000001271 168.0
HFD2_k127_2153083_44 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.00000000000000000000000000000000000000000002183 173.0
HFD2_k127_2153083_45 - - - - 0.0000000000000000000000000000000000000000001281 165.0
HFD2_k127_2153083_46 IstB domain protein ATP-binding protein - - - 0.000000000000000000000000000000000003668 138.0
HFD2_k127_2153083_47 N-acetylglucosamine kinase activity K00884 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363 2.7.1.59 0.000000000000000000000000000000000003691 150.0
HFD2_k127_2153083_48 - - - - 0.000000000000000000000000000000000005048 152.0
HFD2_k127_2153083_49 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000005812 159.0
HFD2_k127_2153083_5 PFAM Uncharacterised BCR, COG1649 - - - 1.071e-262 831.0
HFD2_k127_2153083_50 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000001317 134.0
HFD2_k127_2153083_51 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000008277 128.0
HFD2_k127_2153083_52 DNA-binding transcription factor activity K02444,K03655 - 3.6.4.12 0.000000000000000000000000001075 124.0
HFD2_k127_2153083_53 DNA-binding transcription factor activity K02444,K03655 - 3.6.4.12 0.000000000000000000000000002056 122.0
HFD2_k127_2153083_54 pectinesterase activity K10297,K15923,K18197,K20276 - 3.2.1.51,4.2.2.23 0.00000000000000000000003027 114.0
HFD2_k127_2153083_55 PFAM Uncharacterised BCR, COG1649 K01186,K01197,K05988,K11931 - 3.2.1.11,3.2.1.18,3.2.1.35 0.000000000000000000002379 98.0
HFD2_k127_2153083_56 exo-alpha-(2->6)-sialidase activity K01186 - 3.2.1.18 0.0000000000000000001538 105.0
HFD2_k127_2153083_57 GxGYxYP putative glycoside hydrolase C-terminal domain K03088 - - 0.000000000000000005041 99.0
HFD2_k127_2153083_58 Sulfatase-modifying factor enzyme 1 K01176,K01206,K01218,K01219,K01224 - 3.2.1.1,3.2.1.51,3.2.1.78,3.2.1.81,3.2.1.89 0.00000000000000001015 98.0
HFD2_k127_2153083_59 - - - - 0.000000000000005819 81.0
HFD2_k127_2153083_6 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 9.103e-241 779.0
HFD2_k127_2153083_60 - - - - 0.0000000000001502 84.0
HFD2_k127_2153083_61 Universal stress protein K06149 - - 0.0000000001291 68.0
HFD2_k127_2153083_62 addiction module antidote protein, CC2985 family - - - 0.00000000636 67.0
HFD2_k127_2153083_63 PFAM conserved - - - 0.00000003844 55.0
HFD2_k127_2153083_7 - - - - 4.694e-229 751.0
HFD2_k127_2153083_8 Aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 6.269e-222 698.0
HFD2_k127_2153083_9 TonB-dependent receptor - - - 8.345e-196 644.0
HFD2_k127_2207995_0 DNA-directed 5'-3' RNA polymerase activity K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1938.0
HFD2_k127_2207995_1 protein targeting K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1314.0
HFD2_k127_2207995_10 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 2.025e-233 736.0
HFD2_k127_2207995_100 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000006149 201.0
HFD2_k127_2207995_101 spore germination K07790 - - 0.00000000000000000000000000000000000000000000000000000003424 208.0
HFD2_k127_2207995_102 glycolate biosynthetic process K01091,K06019 - 3.1.3.18,3.6.1.1 0.00000000000000000000000000000000000000000000000000000005934 204.0
HFD2_k127_2207995_103 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000008118 204.0
HFD2_k127_2207995_104 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000001566 194.0
HFD2_k127_2207995_105 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000004487 195.0
HFD2_k127_2207995_106 cell redox homeostasis - - - 0.00000000000000000000000000000000000000000000000000002001 209.0
HFD2_k127_2207995_107 PFAM Fimbrial assembly family protein K02663 - - 0.000000000000000000000000000000000000000000000000001109 202.0
HFD2_k127_2207995_108 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000001923 191.0
HFD2_k127_2207995_109 HIT domain K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000002806 192.0
HFD2_k127_2207995_11 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 1.121e-228 724.0
HFD2_k127_2207995_110 Belongs to the P(II) protein family K04751,K04752 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006808,GO:0008144,GO:0008150,GO:0009889,GO:0010565,GO:0017076,GO:0019216,GO:0019217,GO:0019222,GO:0030234,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042304,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0046890,GO:0050789,GO:0050790,GO:0050794,GO:0062012,GO:0065007,GO:0065009,GO:0080090,GO:0097159,GO:0097367,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000001172 179.0
HFD2_k127_2207995_111 cellulose binding K07279 - - 0.0000000000000000000000000000000000000000000000002339 194.0
HFD2_k127_2207995_112 Involved in the binding of tRNA to the ribosomes K02946 GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000004274 174.0
HFD2_k127_2207995_113 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000172 172.0
HFD2_k127_2207995_114 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000001804 175.0
HFD2_k127_2207995_115 PFAM sigma-70 region 2 domain protein K03088 - - 0.00000000000000000000000000000000000000000000003274 176.0
HFD2_k127_2207995_116 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000001615 175.0
HFD2_k127_2207995_117 - K07275 - - 0.0000000000000000000000000000000000000000000001671 181.0
HFD2_k127_2207995_118 2 iron, 2 sulfur cluster binding K00334,K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000001991 171.0
HFD2_k127_2207995_119 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000002 170.0
HFD2_k127_2207995_12 ferrous iron transmembrane transporter activity K04759 - - 1.921e-222 709.0
HFD2_k127_2207995_120 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000228 183.0
HFD2_k127_2207995_121 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000001576 166.0
HFD2_k127_2207995_122 Putative heavy-metal-binding - - - 0.0000000000000000000000000000000000000000001625 160.0
HFD2_k127_2207995_123 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000001982 162.0
HFD2_k127_2207995_124 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864,K02935 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000005654 164.0
HFD2_k127_2207995_125 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000003411 158.0
HFD2_k127_2207995_126 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000005481 161.0
HFD2_k127_2207995_127 Highly conserved protein containing a thioredoxin domain K18581 - 3.2.1.180 0.000000000000000000000000000000000000000005705 161.0
HFD2_k127_2207995_128 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000001032 154.0
HFD2_k127_2207995_129 rRNA binding K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.00000000000000000000000000000000000000002878 157.0
HFD2_k127_2207995_13 translation elongation factor activity K02358,K15771 GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0010467,GO:0016020,GO:0019538,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0034641,GO:0034645,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071704,GO:0071944,GO:0090087,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - 1.901e-220 689.0
HFD2_k127_2207995_130 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000004705 166.0
HFD2_k127_2207995_131 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.00000000000000000000000000000000000004215 148.0
HFD2_k127_2207995_132 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000002669 147.0
HFD2_k127_2207995_133 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000297 145.0
HFD2_k127_2207995_134 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000004862 150.0
HFD2_k127_2207995_135 4fe-4S ferredoxin, iron-sulfur binding domain protein K03522,K05337 - - 0.000000000000000000000000000000000001886 141.0
HFD2_k127_2207995_136 mitochondrial genome maintenance K02879,K16193 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000006433 143.0
HFD2_k127_2207995_137 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.00000000000000000000000000000000005987 138.0
HFD2_k127_2207995_138 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000008088 138.0
HFD2_k127_2207995_139 - - - - 0.0000000000000000000000000000000001249 144.0
HFD2_k127_2207995_14 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 3.271e-218 694.0
HFD2_k127_2207995_140 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000000000000265 132.0
HFD2_k127_2207995_141 cellulose binding - - - 0.0000000000000000000000000000000008326 150.0
HFD2_k127_2207995_142 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000004692 134.0
HFD2_k127_2207995_144 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000946 132.0
HFD2_k127_2207995_145 Pfam:DUF59 K02612 - - 0.0000000000000000000000000000001095 126.0
HFD2_k127_2207995_146 regulation of translation K03530,K05788 - - 0.0000000000000000000000000000001959 125.0
HFD2_k127_2207995_147 PFAM transcription elongation factor GreA GreB domain protein K06140 - - 0.0000000000000000000000000000973 121.0
HFD2_k127_2207995_148 - - - - 0.0000000000000000000000000001148 119.0
HFD2_k127_2207995_149 Methyltransferase domain protein - - - 0.0000000000000000000000000001385 125.0
HFD2_k127_2207995_15 Polysaccharide biosynthesis protein K02851 - 2.7.8.33,2.7.8.35 1.522e-215 683.0
HFD2_k127_2207995_150 amine dehydrogenase activity - - - 0.0000000000000000000000000008157 124.0
HFD2_k127_2207995_151 - - - - 0.000000000000000000000000001685 124.0
HFD2_k127_2207995_152 DNA mediated transformation - - - 0.00000000000000000000000001124 123.0
HFD2_k127_2207995_153 rRNA binding K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000006021 111.0
HFD2_k127_2207995_154 gas vesicle protein - - - 0.0000000000000000000000001756 110.0
HFD2_k127_2207995_155 chlorophyll binding K16191,K20276 - - 0.0000000000000000000000002507 116.0
HFD2_k127_2207995_156 Cobalt transport protein K02008 - - 0.0000000000000000000000008588 111.0
HFD2_k127_2207995_157 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000003122 103.0
HFD2_k127_2207995_158 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000002231 111.0
HFD2_k127_2207995_159 rRNA binding K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000001659 97.0
HFD2_k127_2207995_16 protein transport K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 2.537e-210 662.0
HFD2_k127_2207995_160 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000001501 97.0
HFD2_k127_2207995_161 - - - - 0.00000000000000000002445 95.0
HFD2_k127_2207995_162 deoxyhypusine monooxygenase activity - - - 0.00000000000000000008972 104.0
HFD2_k127_2207995_163 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000001234 91.0
HFD2_k127_2207995_164 - - - - 0.000000000000000001357 95.0
HFD2_k127_2207995_165 carboxymethylenebutenolidase activity K01061,K06889 - 3.1.1.45 0.000000000000000001825 99.0
HFD2_k127_2207995_167 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000008231 84.0
HFD2_k127_2207995_168 cytochrome complex assembly K02200,K04018 - - 0.00000000000000001509 93.0
HFD2_k127_2207995_169 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000005126 87.0
HFD2_k127_2207995_17 TonB-dependent receptor - - - 1.66e-209 685.0
HFD2_k127_2207995_170 Methylmuconolactone methyl-isomerase - - - 0.00000000000000006401 85.0
HFD2_k127_2207995_171 Ribosomal protein L33 K02913 - - 0.0000000000000001064 80.0
HFD2_k127_2207995_172 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000002777 80.0
HFD2_k127_2207995_173 Protein of unknown function (DUF2911) - - - 0.0000000000000003092 92.0
HFD2_k127_2207995_175 cellulase activity K06882 - - 0.00000000000004244 83.0
HFD2_k127_2207995_176 histone H1-like protein - - - 0.00000000000006026 75.0
HFD2_k127_2207995_177 His Kinase A (phosphoacceptor) domain - - - 0.0000000000002507 76.0
HFD2_k127_2207995_178 Ribosomal protein L36 K02919 - - 0.000000000003068 68.0
HFD2_k127_2207995_179 Glycosyl transferase family 41 - - - 0.000000000008312 78.0
HFD2_k127_2207995_18 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.865e-205 656.0
HFD2_k127_2207995_181 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000009595 64.0
HFD2_k127_2207995_183 TIGRFAM TonB family protein K03832 - - 0.000000002566 69.0
HFD2_k127_2207995_184 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000002646 64.0
HFD2_k127_2207995_185 snoRNA binding - - - 0.00000001183 61.0
HFD2_k127_2207995_186 GlcNAc-PI de-N-acetylase - - - 0.0000001157 65.0
HFD2_k127_2207995_187 - - - - 0.0000001599 55.0
HFD2_k127_2207995_19 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 593.0
HFD2_k127_2207995_190 - - - - 0.000007112 48.0
HFD2_k127_2207995_192 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0001668 44.0
HFD2_k127_2207995_193 FeoA K04758 - - 0.0002551 49.0
HFD2_k127_2207995_194 PFAM LmbE family protein - - - 0.0002646 54.0
HFD2_k127_2207995_195 Histidine kinase - - - 0.0003457 48.0
HFD2_k127_2207995_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1301.0
HFD2_k127_2207995_20 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007883 598.0
HFD2_k127_2207995_21 acyl-CoA dehydrogenase activity K06446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 582.0
HFD2_k127_2207995_22 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 580.0
HFD2_k127_2207995_23 CTP:tRNA cytidylyltransferase activity K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 571.0
HFD2_k127_2207995_24 NAD binding K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 552.0
HFD2_k127_2207995_25 protein transport across the cell outer membrane K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 539.0
HFD2_k127_2207995_26 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 527.0
HFD2_k127_2207995_27 PFAM aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 501.0
HFD2_k127_2207995_28 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 499.0
HFD2_k127_2207995_29 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 485.0
HFD2_k127_2207995_3 response to heat K03696 - - 0.0 1223.0
HFD2_k127_2207995_30 Belongs to the cysteine synthase cystathionine beta- synthase family K01697,K01738,K12339 - 2.5.1.47,4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 473.0
HFD2_k127_2207995_31 homocysteine catabolic process K01372,K02316 - 3.4.22.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 474.0
HFD2_k127_2207995_32 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 467.0
HFD2_k127_2207995_33 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005795 468.0
HFD2_k127_2207995_34 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000795 458.0
HFD2_k127_2207995_35 ferredoxin-NADP+ reductase activity K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 452.0
HFD2_k127_2207995_36 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 462.0
HFD2_k127_2207995_37 Belongs to the ATCase OTCase family K00608,K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009669 446.0
HFD2_k127_2207995_38 RNA polymerase activity K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 422.0
HFD2_k127_2207995_39 Predicted membrane protein (DUF2339) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 445.0
HFD2_k127_2207995_4 nucleotide-excision repair K03701 - - 0.0 1073.0
HFD2_k127_2207995_40 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000806 445.0
HFD2_k127_2207995_41 ATP-dependent DNA helicase activity K16898 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 449.0
HFD2_k127_2207995_42 rRNA binding K02886 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 406.0
HFD2_k127_2207995_43 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 404.0
HFD2_k127_2207995_44 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 388.0
HFD2_k127_2207995_45 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 385.0
HFD2_k127_2207995_46 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 379.0
HFD2_k127_2207995_47 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 381.0
HFD2_k127_2207995_48 exonuclease activity K16899 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 403.0
HFD2_k127_2207995_49 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 378.0
HFD2_k127_2207995_5 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0 1066.0
HFD2_k127_2207995_50 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 377.0
HFD2_k127_2207995_51 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 403.0
HFD2_k127_2207995_52 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 367.0
HFD2_k127_2207995_53 SMART PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 366.0
HFD2_k127_2207995_54 4-amino-4-deoxy-L-arabinose transferase activity K13687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 378.0
HFD2_k127_2207995_55 inositol 2-dehydrogenase activity K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 361.0
HFD2_k127_2207995_56 nitronate monooxygenase activity K02371 - 1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005091 353.0
HFD2_k127_2207995_57 lipoprotein transporter activity K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 350.0
HFD2_k127_2207995_58 NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 339.0
HFD2_k127_2207995_59 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 328.0
HFD2_k127_2207995_6 DEAD DEAH box helicase K03724 - - 4.158e-318 1026.0
HFD2_k127_2207995_60 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 324.0
HFD2_k127_2207995_61 regulation of translation K02863 GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 319.0
HFD2_k127_2207995_62 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 322.0
HFD2_k127_2207995_63 rRNA binding K02986 GO:0000028,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006446,GO:0006450,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030371,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032269,GO:0032270,GO:0032991,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045727,GO:0045903,GO:0045947,GO:0048027,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990145,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 316.0
HFD2_k127_2207995_64 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 327.0
HFD2_k127_2207995_65 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 312.0
HFD2_k127_2207995_66 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 322.0
HFD2_k127_2207995_67 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 295.0
HFD2_k127_2207995_68 Peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 293.0
HFD2_k127_2207995_69 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 293.0
HFD2_k127_2207995_7 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.556e-287 904.0
HFD2_k127_2207995_70 beta-lactamase activity K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005039 295.0
HFD2_k127_2207995_71 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009136 282.0
HFD2_k127_2207995_72 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001939 298.0
HFD2_k127_2207995_73 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000302 287.0
HFD2_k127_2207995_74 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007588 265.0
HFD2_k127_2207995_75 cellulase activity K06882 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001001 266.0
HFD2_k127_2207995_76 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001566 259.0
HFD2_k127_2207995_77 Bacterial type II and III secretion system protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002914 269.0
HFD2_k127_2207995_78 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001803 261.0
HFD2_k127_2207995_79 tRNA binding K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001984 256.0
HFD2_k127_2207995_8 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 5.008e-252 791.0
HFD2_k127_2207995_80 Part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003771 259.0
HFD2_k127_2207995_81 rRNA binding K02988 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002098 253.0
HFD2_k127_2207995_82 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000004458 244.0
HFD2_k127_2207995_83 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000723 235.0
HFD2_k127_2207995_84 Forms part of the polypeptide exit tunnel K02926,K16193 GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000001431 238.0
HFD2_k127_2207995_85 uracil phosphoribosyltransferase activity K02825 GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000001078 236.0
HFD2_k127_2207995_86 tRNA binding K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000004635 231.0
HFD2_k127_2207995_87 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000001971 237.0
HFD2_k127_2207995_88 rRNA binding K02933 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000009257 224.0
HFD2_k127_2207995_89 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000001948 224.0
HFD2_k127_2207995_9 - - - - 5.463e-250 809.0
HFD2_k127_2207995_90 PDGLE domain K02007 - - 0.00000000000000000000000000000000000000000000000000000000000001205 227.0
HFD2_k127_2207995_91 leucyltransferase activity K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000005045 218.0
HFD2_k127_2207995_92 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000001225 212.0
HFD2_k127_2207995_93 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000973 208.0
HFD2_k127_2207995_94 nUDIX hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000002071 211.0
HFD2_k127_2207995_95 rRNA binding K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000251 206.0
HFD2_k127_2207995_96 SMART Tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000002798 226.0
HFD2_k127_2207995_97 efflux transmembrane transporter activity K12340 - - 0.0000000000000000000000000000000000000000000000000000000003198 220.0
HFD2_k127_2207995_98 rRNA processing K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000001861 214.0
HFD2_k127_2207995_99 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.000000000000000000000000000000000000000000000000000000003882 209.0
HFD2_k127_2354801_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K18307 - - 0.0 1414.0
HFD2_k127_2354801_1 GXGXG motif - - - 7.059e-281 890.0
HFD2_k127_2354801_10 Two component regulator propeller K00936 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 622.0
HFD2_k127_2354801_11 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 570.0
HFD2_k127_2354801_12 glutamate decarboxylase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 569.0
HFD2_k127_2354801_13 Pirin C-terminal cupin domain K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 556.0
HFD2_k127_2354801_14 acetate kinase activity K00925,K19697 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1,2.7.2.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 546.0
HFD2_k127_2354801_15 Glutamate synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009856 538.0
HFD2_k127_2354801_16 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 539.0
HFD2_k127_2354801_17 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 503.0
HFD2_k127_2354801_18 Aldo/keto reductase family K05882 - 1.1.1.91 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007183 485.0
HFD2_k127_2354801_19 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 493.0
HFD2_k127_2354801_2 Beta-L-arabinofuranosidase, GH127 - - - 2.118e-239 767.0
HFD2_k127_2354801_20 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 457.0
HFD2_k127_2354801_21 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 427.0
HFD2_k127_2354801_22 Class ii aldolase K01628,K03077,K11216 - 2.7.1.189,4.1.2.17,5.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 389.0
HFD2_k127_2354801_23 Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 384.0
HFD2_k127_2354801_24 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 366.0
HFD2_k127_2354801_25 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008495 360.0
HFD2_k127_2354801_26 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 364.0
HFD2_k127_2354801_27 Aldo Keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009925 358.0
HFD2_k127_2354801_28 Thermolysin metallopeptidase, catalytic domain K01400,K01401,K19351 GO:0005575,GO:0005576 3.4.24.28,3.4.24.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008007 368.0
HFD2_k127_2354801_29 COG2211 Na melibiose symporter and related transporters K03292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 349.0
HFD2_k127_2354801_3 acetyltransferase K11206 - - 2.583e-234 735.0
HFD2_k127_2354801_30 PFAM General secretory system II protein E domain protein K11740 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007346 349.0
HFD2_k127_2354801_31 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 327.0
HFD2_k127_2354801_32 Major facilitator Superfamily K08162,K08226,K16211 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 323.0
HFD2_k127_2354801_33 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 307.0
HFD2_k127_2354801_34 propanediol catabolic process K15024 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 290.0
HFD2_k127_2354801_35 glutamate synthase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001032 282.0
HFD2_k127_2354801_36 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003336 269.0
HFD2_k127_2354801_37 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009068 269.0
HFD2_k127_2354801_38 dihydrofolate reductase activity K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000005042 243.0
HFD2_k127_2354801_39 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000003679 265.0
HFD2_k127_2354801_4 belongs to the aldehyde dehydrogenase family K04021,K13922 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.87 1.791e-233 729.0
HFD2_k127_2354801_40 PFAM Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004826 233.0
HFD2_k127_2354801_41 PFAM Conserved TM helix - - - 0.000000000000000000000000000000000000000000000000000000005633 209.0
HFD2_k127_2354801_42 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000003055 203.0
HFD2_k127_2354801_43 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000007608 203.0
HFD2_k127_2354801_44 LysM domain - - - 0.000000000000000000000000000000000000000000000000000001173 203.0
HFD2_k127_2354801_45 COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) K05770 - - 0.00000000000000000000000000000000000000000000000000002501 193.0
HFD2_k127_2354801_46 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000007399 189.0
HFD2_k127_2354801_47 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000001069 190.0
HFD2_k127_2354801_48 Domain of unknown function (DUF4382) - - - 0.00000000000000000000000000000000000000000000000006039 191.0
HFD2_k127_2354801_49 Domain of unknown function (DUF4382) - - - 0.0000000000000000000000000000000000000000000000006045 186.0
HFD2_k127_2354801_5 Beta-lactamase class C - - - 1.433e-217 690.0
HFD2_k127_2354801_50 thioesterase K01075 - - - 0.0000000000000000000000000000000000000000000000372 180.0
HFD2_k127_2354801_51 Helix-hairpin-helix domain - - - 0.0000000000000000000000000000000000000000000005881 176.0
HFD2_k127_2354801_52 CotH kinase protein K06330 - - 0.000000000000000000000000000000000000000000003802 188.0
HFD2_k127_2354801_53 Domain of unknown function (DUF4382) - - - 0.000000000000000000000000000000000000000000007063 174.0
HFD2_k127_2354801_54 ethanolamine catabolic process K04027,K08696,K08700 - - 0.00000000000000000000000000000000000000009924 151.0
HFD2_k127_2354801_55 BMC - - - 0.000000000000000000000000000000000000001089 159.0
HFD2_k127_2354801_56 ethanolamine catabolic process K04027 - - 0.000000000000000000000000000000000000001175 149.0
HFD2_k127_2354801_57 cellulose binding - - - 0.000000000000000000000000000000000000002563 169.0
HFD2_k127_2354801_58 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.0000000000000000000000000000000000001366 145.0
HFD2_k127_2354801_59 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase - - - 0.0000000000000000000000000000000000004904 145.0
HFD2_k127_2354801_6 FAD dependent oxidoreductase - - - 3.941e-209 663.0
HFD2_k127_2354801_60 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000000000000000002427 142.0
HFD2_k127_2354801_61 Protein of unknown function (DUF1697) - - - 0.0000000000000000000000000000000002553 139.0
HFD2_k127_2354801_62 PFAM Bacterial regulatory protein, arsR family - - - 0.0000000000000000000000000000000003372 134.0
HFD2_k127_2354801_63 DeoR C terminal sensor domain - GO:0005975,GO:0006066,GO:0006071,GO:0006355,GO:0008150,GO:0008152,GO:0009056,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016052,GO:0019219,GO:0019222,GO:0019400,GO:0019405,GO:0019563,GO:0019751,GO:0031323,GO:0031326,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901575,GO:1901615,GO:1901616,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000006842 137.0
HFD2_k127_2354801_64 ethanolamine catabolic process - - - 0.00000000000000000000000000000001639 133.0
HFD2_k127_2354801_65 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.0000000000000000000000000000006041 124.0
HFD2_k127_2354801_66 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.000000000000000000000000000003086 123.0
HFD2_k127_2354801_67 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.000000000000000000000000000006359 121.0
HFD2_k127_2354801_68 - - - - 0.000000000000000000000000001273 124.0
HFD2_k127_2354801_69 metallopeptidase activity K01179,K01181 - 3.2.1.4,3.2.1.8 0.000000000000000000000002969 117.0
HFD2_k127_2354801_7 Serine threonine protein kinase K12132 - 2.7.11.1 4.776e-203 655.0
HFD2_k127_2354801_70 Histidine kinase K07777 - 2.7.13.3 0.0000000000000000000004412 113.0
HFD2_k127_2354801_71 Tetratricopeptide repeat - - - 0.000000000000000000001417 108.0
HFD2_k127_2354801_72 Zinc metalloprotease (Elastase) K20274 - - 0.000000000000000000007325 109.0
HFD2_k127_2354801_73 PFAM regulatory protein LuxR - - - 0.00000000000000000003905 95.0
HFD2_k127_2354801_74 Protein of unknown function (DUF2630) - - - 0.000000000000000136 81.0
HFD2_k127_2354801_75 Flavin containing amine oxidoreductase - - - 0.00000000000006255 74.0
HFD2_k127_2354801_76 methyltransferase K02169 - 2.1.1.197 0.0000000000001519 77.0
HFD2_k127_2354801_77 - - - - 0.00000000001037 68.0
HFD2_k127_2354801_78 Signal transduction histidine kinase regulating citrate malate metabolism K02476,K07701,K11614 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016020,GO:0016021,GO:0016043,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0031323,GO:0031326,GO:0035556,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051259,GO:0051260,GO:0051716,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0140096,GO:1901564,GO:1903506,GO:2000112,GO:2001141 2.7.13.3 0.00000000001129 79.0
HFD2_k127_2354801_79 cob(I)yrinic acid a,c-diamide adenosyltransferase activity K04032 - 2.5.1.17 0.0000000001836 68.0
HFD2_k127_2354801_8 amino acid carrier protein K03310 - - 2.164e-196 622.0
HFD2_k127_2354801_80 - - - - 0.0000000001954 71.0
HFD2_k127_2354801_82 efflux transmembrane transporter activity K12340 - - 0.000000000897 71.0
HFD2_k127_2354801_83 - - - - 0.00000002964 65.0
HFD2_k127_2354801_84 Domain of unknown function (DUF4149) - - - 0.0000003356 60.0
HFD2_k127_2354801_85 Belongs to the peptidase S8 family K13275 - - 0.000007772 53.0
HFD2_k127_2354801_86 Belongs to the 'phage' integrase family - - - 0.0006963 48.0
HFD2_k127_2354801_87 His Kinase A (phosphoacceptor) domain - - - 0.0007259 45.0
HFD2_k127_2354801_88 Phosphoadenosine phosphosulfate reductase family K05907 GO:0000103,GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009973,GO:0009987,GO:0016491,GO:0016667,GO:0016671,GO:0019379,GO:0019419,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0055114 1.8.4.9 0.0007678 48.0
HFD2_k127_2354801_9 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 622.0
HFD2_k127_2708170_0 FeoA - - - 3.674e-212 668.0
HFD2_k127_2708170_1 Trehalase K01194 - 3.2.1.28 7.215e-201 647.0
HFD2_k127_2708170_10 Bacterial regulatory proteins, luxR family - - - 0.0000000000000000000000000000000004865 140.0
HFD2_k127_2708170_11 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000003577 134.0
HFD2_k127_2708170_12 polysaccharide deacetylase - - - 0.00000000000000000000002141 119.0
HFD2_k127_2708170_13 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000001764 97.0
HFD2_k127_2708170_15 NHL repeat containing protein - - - 0.000000003845 63.0
HFD2_k127_2708170_2 Serine threonine protein kinase K12132 - 2.7.11.1 5.447e-196 640.0
HFD2_k127_2708170_3 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008507 571.0
HFD2_k127_2708170_4 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 479.0
HFD2_k127_2708170_5 ferrous iron transmembrane transporter activity K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 350.0
HFD2_k127_2708170_6 iron ion homeostasis K03322,K03709,K04758 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 304.0
HFD2_k127_2708170_7 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 289.0
HFD2_k127_2708170_8 FeoA K03709 - - 0.000000000000000000000000000000000000000000000000001468 190.0
HFD2_k127_2708170_9 hydrolase, family 25 - - - 0.00000000000000000000000000000000000000000000002688 198.0
HFD2_k127_2785233_0 4 iron, 4 sulfur cluster binding K00184 - - 0.0 1116.0
HFD2_k127_2785233_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 5.566e-286 904.0
HFD2_k127_2785233_10 TIGRFAM Ammonium transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008606 491.0
HFD2_k127_2785233_11 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 463.0
HFD2_k127_2785233_12 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 469.0
HFD2_k127_2785233_13 Periplasmic component of the Tol biopolymer transport system K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006521 437.0
HFD2_k127_2785233_14 zinc ion transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 431.0
HFD2_k127_2785233_15 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH K22136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 406.0
HFD2_k127_2785233_16 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 400.0
HFD2_k127_2785233_17 L-allo-threonine aldolase activity K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 379.0
HFD2_k127_2785233_18 aminopeptidase activity K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 349.0
HFD2_k127_2785233_19 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 347.0
HFD2_k127_2785233_2 polyribonucleotide nucleotidyltransferase activity K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.73e-255 806.0
HFD2_k127_2785233_20 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 307.0
HFD2_k127_2785233_21 Cytochrome c K02720 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001143 276.0
HFD2_k127_2785233_22 thymidine kinase activity K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000001848 267.0
HFD2_k127_2785233_23 Ribulose-phosphate 3 epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000004944 267.0
HFD2_k127_2785233_24 riboflavin kinase activity K07011,K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000009976 274.0
HFD2_k127_2785233_25 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000007186 260.0
HFD2_k127_2785233_26 Belongs to the enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000002363 248.0
HFD2_k127_2785233_27 purine ribonucleoside salvage K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000003788 239.0
HFD2_k127_2785233_28 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000227 239.0
HFD2_k127_2785233_29 Phosphorylase superfamily K00772,K03783 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000007439 239.0
HFD2_k127_2785233_3 heme-copper terminal oxidase activity K02274 - 1.9.3.1 4.384e-254 795.0
HFD2_k127_2785233_30 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000007655 240.0
HFD2_k127_2785233_31 signal sequence binding K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000001903 237.0
HFD2_k127_2785233_32 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000004806 228.0
HFD2_k127_2785233_33 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000676 205.0
HFD2_k127_2785233_34 Cytochrome c K07243 - - 0.000000000000000000000000000000000000000000000000000000002067 211.0
HFD2_k127_2785233_35 Cytochrome c, class I K08738 - - 0.0000000000000000000000000000000000000000000000000000006256 210.0
HFD2_k127_2785233_36 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000001421 202.0
HFD2_k127_2785233_37 FtsZ-dependent cytokinesis - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000007941 196.0
HFD2_k127_2785233_38 PFAM regulatory protein AsnC Lrp family K03719 - - 0.0000000000000000000000000000000000000000000000002891 180.0
HFD2_k127_2785233_39 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000001343 183.0
HFD2_k127_2785233_4 glutamine synthetase K01915 - 6.3.1.2 4.033e-252 784.0
HFD2_k127_2785233_40 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000000000000000000000000000000004178 185.0
HFD2_k127_2785233_41 phosphatidate phosphatase activity K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.0000000000000000000000000000000000000002637 158.0
HFD2_k127_2785233_42 KR domain - - - 0.000000000000000000000000000000000000006752 156.0
HFD2_k127_2785233_43 carbon-nitrogen ligase activity, with glutamine as amido-N-donor K09117 - - 0.000000000000000000000000000000000000013 149.0
HFD2_k127_2785233_44 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000000000000000008749 147.0
HFD2_k127_2785233_45 rRNA binding K02956 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000001735 130.0
HFD2_k127_2785233_46 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000002803 126.0
HFD2_k127_2785233_47 Protein of unknown function (DUF971) - - - 0.00000000000000000000000001731 111.0
HFD2_k127_2785233_48 rRNA processing K02834 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000004903 106.0
HFD2_k127_2785233_49 ribosomal small subunit biogenesis K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000001622 106.0
HFD2_k127_2785233_5 Methylmalonyl-CoA mutase K01848,K11942 - 5.4.99.13,5.4.99.2 1.749e-243 764.0
HFD2_k127_2785233_50 Zincin-like metallopeptidase - - - 0.00000000000000000000008388 105.0
HFD2_k127_2785233_52 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000000000003048 89.0
HFD2_k127_2785233_55 Hemerythrin HHE cation binding domain - - - 0.0000004479 58.0
HFD2_k127_2785233_56 ArgK protein K07588 - - 0.000004869 49.0
HFD2_k127_2785233_6 Polysulphide reductase, NrfD K00185 - - 7.616e-231 736.0
HFD2_k127_2785233_7 tryptophanase activity K01667 - 4.1.99.1 4.057e-219 689.0
HFD2_k127_2785233_8 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 564.0
HFD2_k127_2785233_9 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 507.0
HFD2_k127_2843079_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 344.0
HFD2_k127_2915969_0 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 306.0
HFD2_k127_2915969_1 FG-GAP repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002637 269.0
HFD2_k127_2915969_2 TIGRFAM PAS sensor protein - - - 0.0000000000000000000000000000000000000000000000003194 203.0
HFD2_k127_2915969_3 KaiB K08481 - - 0.0000000000000000000000000000001731 130.0
HFD2_k127_2915969_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000003366 94.0
HFD2_k127_2915969_5 PFAM KaiB domain K08481 - - 0.0000001454 55.0
HFD2_k127_2915969_6 His Kinase A (phosphoacceptor) domain K10125 - 2.7.13.3 0.0000005478 64.0
HFD2_k127_3559432_0 Belongs to the peptidase S8 family - - - 4.688e-294 939.0
HFD2_k127_3559432_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.877e-281 899.0
HFD2_k127_3559432_10 Thioredoxin reductase K07222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 385.0
HFD2_k127_3559432_11 Binding-protein-dependent transport system inner membrane component K02025,K17322 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 375.0
HFD2_k127_3559432_12 Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 402.0
HFD2_k127_3559432_13 binding-protein-dependent transport systems inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 367.0
HFD2_k127_3559432_14 beta-glucosidase activity K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 358.0
HFD2_k127_3559432_15 Highly conserved protein containing a thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006662 340.0
HFD2_k127_3559432_16 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 325.0
HFD2_k127_3559432_17 Alcohol dehydrogenase GroES domain protein K00004 - 1.1.1.303,1.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 309.0
HFD2_k127_3559432_18 PFAM binding-protein-dependent transport systems inner membrane component K02025,K17242 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 299.0
HFD2_k127_3559432_19 Glucose dehydrogenase C-terminus K00008,K00060 - 1.1.1.103,1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009374 296.0
HFD2_k127_3559432_2 Concanavalin A-like lectin/glucanases superfamily - - - 3.096e-269 862.0
HFD2_k127_3559432_20 transferase activity, transferring glycosyl groups K20885 - 2.4.1.339,2.4.1.340 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000371 287.0
HFD2_k127_3559432_21 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000009282 266.0
HFD2_k127_3559432_22 succinyl-diaminopimelate desuccinylase activity K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000006449 259.0
HFD2_k127_3559432_23 COGs COG0395 ABC-type sugar transport system permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004389 248.0
HFD2_k127_3559432_24 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000009067 239.0
HFD2_k127_3559432_25 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000004035 220.0
HFD2_k127_3559432_26 nucleotide catabolic process K05996 - 3.4.17.18 0.0000000000000000000000000000000000000000000003774 187.0
HFD2_k127_3559432_27 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000008889 178.0
HFD2_k127_3559432_28 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000006741 166.0
HFD2_k127_3559432_29 cellulose binding - - - 0.00000000000000000000000000000000000000008256 161.0
HFD2_k127_3559432_3 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 5.319e-243 780.0
HFD2_k127_3559432_30 Extracellular solute-binding protein - - - 0.000000000000000000000000000000000000002524 165.0
HFD2_k127_3559432_31 DinB superfamily - - - 0.000000000000000000000000000000000000008316 151.0
HFD2_k127_3559432_32 - - - - 0.0000000000000000000000000000000000002683 151.0
HFD2_k127_3559432_33 protein secretion K09800 - - 0.00000000000000000000000000000000004014 143.0
HFD2_k127_3559432_34 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000001677 147.0
HFD2_k127_3559432_35 protein conserved in bacteria - - - 0.0000000000000000000000000000000005606 143.0
HFD2_k127_3559432_36 cyclic nucleotide binding K07058,K14266 - 1.14.19.9 0.000000000000000000000000000007289 124.0
HFD2_k127_3559432_37 PFAM oxidoreductase - - - 0.00000000000000000000000000003368 129.0
HFD2_k127_3559432_38 SatD family (SatD) - - - 0.0000000000000000000000000004671 127.0
HFD2_k127_3559432_39 - - - - 0.000000000000000000000000006247 129.0
HFD2_k127_3559432_4 Periplasmic component of the Tol biopolymer transport system - - - 7.295e-209 663.0
HFD2_k127_3559432_40 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000008232 121.0
HFD2_k127_3559432_41 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00000000000000000000000009797 110.0
HFD2_k127_3559432_42 cellulose binding - - - 0.0000000000000000000000001799 118.0
HFD2_k127_3559432_43 Protein of unknown function (DUF3307) - - - 0.00000000000000009145 90.0
HFD2_k127_3559432_44 TIGRFAM type I secretion outer membrane protein, TolC family K12340 GO:0002790,GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0008104,GO:0008150,GO:0009279,GO:0009306,GO:0009987,GO:0010033,GO:0014070,GO:0015031,GO:0015075,GO:0015267,GO:0015288,GO:0015318,GO:0015562,GO:0015688,GO:0015711,GO:0015833,GO:0015850,GO:0015891,GO:0015893,GO:0016020,GO:0016021,GO:0019867,GO:0022803,GO:0022829,GO:0022838,GO:0022857,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032940,GO:0032991,GO:0033036,GO:0034220,GO:0042221,GO:0042493,GO:0042802,GO:0042886,GO:0042930,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0046618,GO:0046903,GO:0047485,GO:0050896,GO:0051179,GO:0051181,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098796,GO:1901678,GO:1902495,GO:1990195,GO:1990196,GO:1990281,GO:1990351 - 0.000000000000002388 89.0
HFD2_k127_3559432_45 Planctomycete cytochrome C - - - 0.000000000000008522 78.0
HFD2_k127_3559432_46 PPIC-type PPIASE domain - - - 0.0000000009266 71.0
HFD2_k127_3559432_47 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K06378 - - 0.0000002437 56.0
HFD2_k127_3559432_48 Glycosyl hydrolase 36 superfamily, catalytic domain K00702 - 2.4.1.20 0.0001398 56.0
HFD2_k127_3559432_5 beta-galactosidase activity K01192 - 3.2.1.25 5.082e-197 643.0
HFD2_k127_3559432_6 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 580.0
HFD2_k127_3559432_7 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family K02100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 495.0
HFD2_k127_3559432_8 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 465.0
HFD2_k127_3559432_9 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009418 411.0
HFD2_k127_3739139_0 protein histidine kinase activity K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000005641 279.0
HFD2_k127_3739139_1 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000001186 171.0
HFD2_k127_3739139_2 23S rRNA-intervening sequence protein - - - 0.000000000000000000000002513 109.0
HFD2_k127_3739139_3 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000000000003173 86.0
HFD2_k127_3739139_4 fibronectin type III domain protein - - - 0.000003394 49.0
HFD2_k127_3739139_5 SnoaL-like domain - - - 0.00001605 55.0
HFD2_k127_3739140_0 1-deoxy-D-xylulose-5-phosphate synthase activity K01662 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 5.883e-270 845.0
HFD2_k127_3739140_1 aspartate-tRNA(Asn) ligase activity K01876 GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.12 8.48e-243 763.0
HFD2_k127_3739140_10 cytochrome complex assembly K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 297.0
HFD2_k127_3739140_11 phosphorelay signal transduction system K07658 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002574 282.0
HFD2_k127_3739140_12 serine-type endopeptidase activity K09973 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000621 293.0
HFD2_k127_3739140_13 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001842 267.0
HFD2_k127_3739140_14 N-acetylglucosaminylinositol deacetylase activity K01463 - - 0.000000000000000000000000000000000000000000000000000000000000000000007313 241.0
HFD2_k127_3739140_15 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.000000000000000000000000000000000000000000000000000000000000000002399 251.0
HFD2_k127_3739140_16 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000003287 237.0
HFD2_k127_3739140_17 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02193,K02194 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000321 219.0
HFD2_k127_3739140_18 cell envelope organization K05807,K08309 - - 0.0000000000000000000000000000000000000000000000000000000005771 211.0
HFD2_k127_3739140_19 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000006216 209.0
HFD2_k127_3739140_2 4-Hydroxyphenylpyruvate dioxygenase - - - 5.544e-203 646.0
HFD2_k127_3739140_20 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000008523 213.0
HFD2_k127_3739140_21 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000002753 202.0
HFD2_k127_3739140_22 acyl-coa hydrolase K01073 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 3.1.2.20 0.00000000000000000000000000000000000000000000000000006899 192.0
HFD2_k127_3739140_23 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000788 201.0
HFD2_k127_3739140_24 acetyltransferase - - - 0.00000000000000000000000000000000000000001007 170.0
HFD2_k127_3739140_25 PFAM ABC transporter related K02193 - 3.6.3.41 0.000000000000000000000000000000000000001892 155.0
HFD2_k127_3739140_26 - - - - 0.000000000000000000000000000000000000004262 149.0
HFD2_k127_3739140_27 PFAM Acetyltransferase (GNAT) family K03790 - 2.3.1.128 0.0000000000000000000000000000000000001984 149.0
HFD2_k127_3739140_28 Cupin domain K11312 - - 0.000000000000000000000000000005995 124.0
HFD2_k127_3739140_29 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000005193 128.0
HFD2_k127_3739140_3 Cytochrome C-type biogenesis protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 550.0
HFD2_k127_3739140_30 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000001128 101.0
HFD2_k127_3739140_31 Predicted membrane protein (DUF2231) - - - 0.00000000000000003751 89.0
HFD2_k127_3739140_32 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000001995 68.0
HFD2_k127_3739140_34 - - - - 0.0001912 50.0
HFD2_k127_3739140_4 translation release factor activity K02836 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 472.0
HFD2_k127_3739140_5 exodeoxyribonuclease VII activity K03601,K03797 - 3.1.11.6,3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 378.0
HFD2_k127_3739140_6 Tryptophanyl-tRNA synthetase K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 369.0
HFD2_k127_3739140_7 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 328.0
HFD2_k127_3739140_8 lipoprotein localization to outer membrane K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 319.0
HFD2_k127_3739140_9 lipoprotein localization to outer membrane K09808,K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 329.0
HFD2_k127_4067469_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002289 252.0
HFD2_k127_4067469_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000001328 231.0
HFD2_k127_4067469_2 ApbE family - - - 0.0000000000000000000000000000000000000000000000000001091 197.0
HFD2_k127_4067469_3 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000003159 158.0
HFD2_k127_4067469_4 Pfam Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000002229 61.0
HFD2_k127_409149_0 deoxyhypusine monooxygenase activity - - - 5.927e-227 737.0
HFD2_k127_409149_1 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 471.0
HFD2_k127_409149_2 formate dehydrogenase K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 325.0
HFD2_k127_42192_0 PFAM Prolyl oligopeptidase family - - - 7.173e-259 813.0
HFD2_k127_42192_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 537.0
HFD2_k127_42192_2 Zinc metalloprotease (Elastase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 410.0
HFD2_k127_42192_3 cellulose binding - - - 0.0000000000000000000000000004348 132.0
HFD2_k127_42192_4 amino acid activation for nonribosomal peptide biosynthetic process K05996 - 3.4.17.18 0.0000000000000000000005233 113.0
HFD2_k127_42192_5 alpha/beta hydrolase fold - - - 0.0000002886 62.0
HFD2_k127_42192_6 peptidyl-tyrosine sulfation - - - 0.0001495 54.0
HFD2_k127_42223_0 Lamin Tail Domain - - - 0.0000000000000000000000000000000000006604 146.0
HFD2_k127_42223_1 cellulose binding - - - 0.00000000000000000000000000001996 133.0
HFD2_k127_4396771_0 nucleotide-excision repair K03701 - - 0.0 1280.0
HFD2_k127_4396771_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03694,K03695 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030312,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0040007,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.0 1094.0
HFD2_k127_4396771_10 Glutamine amidotransferase domain K00764 - 2.4.2.14 9.212e-219 688.0
HFD2_k127_4396771_11 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342 - 1.6.5.3 4.198e-211 669.0
HFD2_k127_4396771_12 single-stranded DNA 5'-3' exodeoxyribonuclease activity K07462 - - 5.659e-199 639.0
HFD2_k127_4396771_13 acyl-CoA dehydrogenase activity K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 606.0
HFD2_k127_4396771_14 NAD binding K00333,K13378 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005584 560.0
HFD2_k127_4396771_15 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 548.0
HFD2_k127_4396771_16 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 541.0
HFD2_k127_4396771_17 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family K02100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 511.0
HFD2_k127_4396771_18 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 503.0
HFD2_k127_4396771_19 acyl-CoA dehydrogenase activity K00248,K11410,K18244 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 469.0
HFD2_k127_4396771_2 unfolded protein binding K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 5.685e-305 946.0
HFD2_k127_4396771_20 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 471.0
HFD2_k127_4396771_21 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 465.0
HFD2_k127_4396771_22 ATP synthesis coupled electron transport K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 464.0
HFD2_k127_4396771_23 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 457.0
HFD2_k127_4396771_24 phosphorelay signal transduction system K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 437.0
HFD2_k127_4396771_25 quinone binding K00337,K05572 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 414.0
HFD2_k127_4396771_26 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 404.0
HFD2_k127_4396771_27 mannose-1-phosphate guanylyltransferase activity K00971,K01840,K16011 - 2.7.7.13,5.3.1.8,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 394.0
HFD2_k127_4396771_28 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 387.0
HFD2_k127_4396771_29 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 384.0
HFD2_k127_4396771_3 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 1.995e-284 901.0
HFD2_k127_4396771_30 e3 binding domain K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 377.0
HFD2_k127_4396771_31 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007347 351.0
HFD2_k127_4396771_32 isobutyryl-CoA mutase activity K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008246 352.0
HFD2_k127_4396771_33 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007045 357.0
HFD2_k127_4396771_34 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007838 334.0
HFD2_k127_4396771_35 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 327.0
HFD2_k127_4396771_36 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 332.0
HFD2_k127_4396771_37 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006757 319.0
HFD2_k127_4396771_38 Belongs to the PdaD family K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 307.0
HFD2_k127_4396771_39 PFAM peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 311.0
HFD2_k127_4396771_4 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 1.324e-255 805.0
HFD2_k127_4396771_40 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 306.0
HFD2_k127_4396771_41 Belongs to the GTP cyclohydrolase I type 2 NIF3 family K07164,K22391 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 303.0
HFD2_k127_4396771_42 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006601 296.0
HFD2_k127_4396771_43 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 300.0
HFD2_k127_4396771_44 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 287.0
HFD2_k127_4396771_45 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 281.0
HFD2_k127_4396771_46 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007539 293.0
HFD2_k127_4396771_47 Multidrug transporter K08161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003438 279.0
HFD2_k127_4396771_48 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000001345 253.0
HFD2_k127_4396771_49 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03615,K05580 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000002088 244.0
HFD2_k127_4396771_5 proton-transporting ATP synthase activity, rotational mechanism K02112 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 3.092e-243 758.0
HFD2_k127_4396771_50 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000001832 238.0
HFD2_k127_4396771_51 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000008942 217.0
HFD2_k127_4396771_52 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000002542 219.0
HFD2_k127_4396771_53 cytoplasmic translational termination K02838 GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000008403 215.0
HFD2_k127_4396771_54 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000002524 211.0
HFD2_k127_4396771_55 lipoprotein biosynthetic process K13292 - - 0.00000000000000000000000000000000000000000000000000000000001426 216.0
HFD2_k127_4396771_56 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000002056 206.0
HFD2_k127_4396771_57 - K07164,K22391 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000009214 198.0
HFD2_k127_4396771_58 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000001498 192.0
HFD2_k127_4396771_59 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.0000000000000000000000000000000000000000000000000001638 195.0
HFD2_k127_4396771_6 CoA carboxylase activity K01966 - 2.1.3.15,6.4.1.3 3.169e-241 756.0
HFD2_k127_4396771_60 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000000002661 183.0
HFD2_k127_4396771_61 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000007954 179.0
HFD2_k127_4396771_62 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000001239 179.0
HFD2_k127_4396771_63 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000004247 177.0
HFD2_k127_4396771_64 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000006203 186.0
HFD2_k127_4396771_65 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000003233 177.0
HFD2_k127_4396771_66 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000005266 165.0
HFD2_k127_4396771_67 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000008457 162.0
HFD2_k127_4396771_68 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000004393 157.0
HFD2_k127_4396771_7 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 3.39e-236 748.0
HFD2_k127_4396771_70 carbon-oxygen lyase activity, acting on polysaccharides K18691 - - 0.00000000000000000000000000000000001212 147.0
HFD2_k127_4396771_71 PspC domain - - - 0.00000000000000000000000000000000004368 144.0
HFD2_k127_4396771_72 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000004746 149.0
HFD2_k127_4396771_73 ATP synthesis coupled electron transport K00340,K05576 - 1.6.5.3 0.0000000000000000000000000000001939 131.0
HFD2_k127_4396771_74 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000003194 123.0
HFD2_k127_4396771_75 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000002448 122.0
HFD2_k127_4396771_76 PFAM ribonuclease H K03469,K06864 - 3.1.26.4 0.0000000000000000000000000001231 123.0
HFD2_k127_4396771_77 phosphorelay signal transduction system - - - 0.0000000000000000000000000003091 117.0
HFD2_k127_4396771_8 cellulose binding - - - 3.85e-230 743.0
HFD2_k127_4396771_80 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000001868 99.0
HFD2_k127_4396771_81 Histidine kinase - - - 0.0000000000000001871 93.0
HFD2_k127_4396771_82 protein trimerization K01999,K08309 - - 0.00000000005935 70.0
HFD2_k127_4396771_84 Protein of unknown function VcgC/VcgE (DUF2780) - - - 0.0000000851 61.0
HFD2_k127_4396771_85 PBCV-specific basic adaptor domain K03646 - - 0.000002769 57.0
HFD2_k127_4396771_87 Pectate lyase K01728 - 4.2.2.2 0.0001514 48.0
HFD2_k127_4396771_9 IMP dehydrogenase activity K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 2.144e-219 691.0
HFD2_k127_4451435_0 Belongs to the transketolase family K00615 - 2.2.1.1 0.0 1212.0
HFD2_k127_4451435_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K11389 - 1.2.7.6 0.0 1092.0
HFD2_k127_4451435_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 1.949e-273 851.0
HFD2_k127_4451435_3 TIGRFAM YidE YbjL duplication K07085 - - 1.501e-252 791.0
HFD2_k127_4451435_4 Ion transport 2 domain protein - - - 0.0000000000000000000000003769 114.0
HFD2_k127_4451435_5 cyclic nucleotide binding K10914 - - 0.000000000000000004053 92.0
HFD2_k127_4451435_6 AI-2E family transporter - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000215 85.0
HFD2_k127_4485519_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1314.0
HFD2_k127_4485519_1 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 445.0
HFD2_k127_4485519_10 exo-alpha-(2->6)-sialidase activity K01186 - 3.2.1.18 0.000000000000000000001072 108.0
HFD2_k127_4485519_11 Belongs to the 5'-nucleotidase family - - - 0.00000000000000000001525 108.0
HFD2_k127_4485519_12 Protein conserved in bacteria - - - 0.000000000000007388 88.0
HFD2_k127_4485519_13 protein secretion K03116,K03117 - - 0.0000000000007206 70.0
HFD2_k127_4485519_14 PFAM Heavy metal transport detoxification protein K08364 - - 0.000000001255 63.0
HFD2_k127_4485519_2 Outer membrane protein beta-barrel family K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 387.0
HFD2_k127_4485519_3 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008993 333.0
HFD2_k127_4485519_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 318.0
HFD2_k127_4485519_6 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000389 229.0
HFD2_k127_4485519_7 cellulose binding - - - 0.0000000000000000000000000000000008771 147.0
HFD2_k127_4485519_8 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000000000002783 133.0
HFD2_k127_4485519_9 Belongs to the peptidase S8 family K01361,K20276 - 3.4.21.96 0.0000000000000000000005522 104.0
HFD2_k127_4523720_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 1.925e-287 899.0
HFD2_k127_4523720_1 polyribonucleotide nucleotidyltransferase activity K02945,K03527,K07571,K12132 GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 1.17.7.4,2.7.11.1 2.414e-252 791.0
HFD2_k127_4523720_10 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004845,GO:0004849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016763,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000001706 256.0
HFD2_k127_4523720_11 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000008334 232.0
HFD2_k127_4523720_12 L-threonylcarbamoyladenylate synthase K07566 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000006855 236.0
HFD2_k127_4523720_13 Belongs to the cytidylate kinase family. Type 1 subfamily K00800,K00945,K03977,K13799 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.19,2.7.4.25,6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000001025 228.0
HFD2_k127_4523720_14 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000001005 214.0
HFD2_k127_4523720_15 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000001019 209.0
HFD2_k127_4523720_16 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K00556,K03218,K03437 - 2.1.1.185,2.1.1.34 0.00000000000000000000000000000000000000000000000000000001322 207.0
HFD2_k127_4523720_17 - - - - 0.000000000000000000000000000000000000000000000000000009305 197.0
HFD2_k127_4523720_18 - - - - 0.0000000000000000000000000000000000001035 151.0
HFD2_k127_4523720_19 response regulator, receiver - - - 0.000000000000000000000000004002 115.0
HFD2_k127_4523720_2 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 4.383e-198 635.0
HFD2_k127_4523720_20 peptidase activity, acting on L-amino acid peptides K03385 - 1.7.2.2 0.00000000000000000000000456 119.0
HFD2_k127_4523720_21 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000017 93.0
HFD2_k127_4523720_22 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000229 60.0
HFD2_k127_4523720_23 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00006446 47.0
HFD2_k127_4523720_3 GTP binding K03977 GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 497.0
HFD2_k127_4523720_4 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 500.0
HFD2_k127_4523720_5 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K18707 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 485.0
HFD2_k127_4523720_6 PFAM Isocitrate isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004835 434.0
HFD2_k127_4523720_7 Protein of unknown function (DUF512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006688 398.0
HFD2_k127_4523720_8 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 312.0
HFD2_k127_4523720_9 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001643 281.0
HFD2_k127_4642797_0 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007923 411.0
HFD2_k127_4642797_1 radical SAM domain protein K22318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 320.0
HFD2_k127_4642797_2 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000002378 166.0
HFD2_k127_4642797_3 Psort location CytoplasmicMembrane, score - - - 0.0000001944 62.0
HFD2_k127_5141484_0 serine-type peptidase activity K08676 - - 0.0 1495.0
HFD2_k127_5141484_1 - - - - 0.0 1223.0
HFD2_k127_5141484_10 Beta-L-arabinofuranosidase, GH127 K09955 - - 2.085e-282 888.0
HFD2_k127_5141484_100 - - - - 0.0000000000000000000000000000000000000000000000000000000000000006505 232.0
HFD2_k127_5141484_101 Belongs to the BI1 family K06890 - - 0.000000000000000000000000000000000000000000000000000000000000001063 226.0
HFD2_k127_5141484_102 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000002184 241.0
HFD2_k127_5141484_103 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000173 220.0
HFD2_k127_5141484_104 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000000000000001983 220.0
HFD2_k127_5141484_105 PFAM 2Fe-2S -binding K03518,K07302,K13483,K20446 - 1.17.1.5,1.2.5.3,1.3.99.16 0.00000000000000000000000000000000000000000000000000000005184 202.0
HFD2_k127_5141484_106 PFAM glycoside hydrolase family 2 sugar binding - - - 0.0000000000000000000000000000000000000000000000000000005277 217.0
HFD2_k127_5141484_107 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079,K21572 - - 0.00000000000000000000000000000000000000000000000000002684 196.0
HFD2_k127_5141484_108 - - - - 0.00000000000000000000000000000000000000000000000000005331 194.0
HFD2_k127_5141484_109 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000006771 203.0
HFD2_k127_5141484_11 PFAM alpha-L-rhamnosidase K05989 - 3.2.1.40 1.347e-259 829.0
HFD2_k127_5141484_110 CO dehydrogenase flavoprotein C-terminal domain K13479 - 1.17.1.4 0.00000000000000000000000000000000000000000000000004206 190.0
HFD2_k127_5141484_111 Negative regulator of - - - 0.000000000000000000000000000000000000000000000001012 201.0
HFD2_k127_5141484_112 - - - - 0.00000000000000000000000000000000000000000000003098 192.0
HFD2_k127_5141484_113 PFAM extracellular solute-binding protein family 1 K02027 - - 0.00000000000000000000000000000000000000000000003975 187.0
HFD2_k127_5141484_114 Acyl-ACP thioesterase K01071 - 3.1.2.21 0.0000000000000000000000000000000000000000000001304 181.0
HFD2_k127_5141484_115 hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000003853 170.0
HFD2_k127_5141484_116 - - - - 0.000000000000000000000000000000000000000001016 164.0
HFD2_k127_5141484_117 polygalacturonase activity - - - 0.000000000000000000000000000000000000000002925 179.0
HFD2_k127_5141484_118 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000000000000000003136 178.0
HFD2_k127_5141484_119 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000000000000000000000000000000000000007415 154.0
HFD2_k127_5141484_12 beta-galactosidase activity K01190,K01195 - 3.2.1.23,3.2.1.31 7.1e-256 810.0
HFD2_k127_5141484_120 metallocarboxypeptidase activity - - - 0.000000000000000000000000000000000000003736 165.0
HFD2_k127_5141484_121 glucan 1,4-alpha-glucosidase activity K05989,K20541 - 3.2.1.40 0.000000000000000000000000000000000003823 158.0
HFD2_k127_5141484_122 cell septum assembly - - - 0.00000000000000000000000000000000135 142.0
HFD2_k127_5141484_123 cellulose binding - - - 0.0000000000000000000000000000008469 141.0
HFD2_k127_5141484_124 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K03574 - 3.6.1.55 0.000000000000000000000000000002722 124.0
HFD2_k127_5141484_125 Sodium:solute symporter family K03307 - - 0.000000000000000000000000004891 126.0
HFD2_k127_5141484_126 cellulase activity K01186,K01197,K05988,K11931,K21449 - 3.2.1.11,3.2.1.18,3.2.1.35 0.00000000000000000000004914 114.0
HFD2_k127_5141484_127 ABC-type sugar transport system, periplasmic component K02027 - - 0.00000000000000000000005854 113.0
HFD2_k127_5141484_128 belongs to the thioredoxin family K03671,K05838 - - 0.000000000000000000006437 103.0
HFD2_k127_5141484_129 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281,K09020 - 3.5.1.110,3.5.1.19 0.00000000000000000003892 100.0
HFD2_k127_5141484_13 GxGYxYP putative glycoside hydrolase C-terminal domain K03088 - - 2.927e-253 798.0
HFD2_k127_5141484_130 PFAM Uncharacterised BCR, COG1649 K01186,K01197,K05988,K11931,K18197 - 3.2.1.11,3.2.1.18,3.2.1.35,4.2.2.23 0.00000000000000000005879 107.0
HFD2_k127_5141484_131 Domain of unknown function (DUF4962) - - - 0.00000000000000000018 104.0
HFD2_k127_5141484_133 PFAM Uncharacterised BCR, COG1649 - - - 0.00000000000000002689 87.0
HFD2_k127_5141484_134 PFAM Uncharacterised BCR, COG1649 K01186,K01197,K05988,K11931,K18197 - 3.2.1.11,3.2.1.18,3.2.1.35,4.2.2.23 0.0000000000000005091 91.0
HFD2_k127_5141484_135 - - - - 0.00000000000000305 85.0
HFD2_k127_5141484_136 peptidyl-prolyl cis-trans isomerase activity K01802,K03769,K07533 - 5.2.1.8 0.000000000000004096 89.0
HFD2_k127_5141484_137 - - - - 0.0000000000000051 78.0
HFD2_k127_5141484_138 - - - - 0.000000000000008827 83.0
HFD2_k127_5141484_139 Acetyltransferase (GNAT) domain - - - 0.00000000000006756 78.0
HFD2_k127_5141484_14 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K13482 - 1.17.1.4 5.779e-249 792.0
HFD2_k127_5141484_140 Cysteine-rich motif following a subset of SET domains K07117 - - 0.0000000000001582 78.0
HFD2_k127_5141484_141 SnoaL-like domain - - - 0.0000000001734 68.0
HFD2_k127_5141484_142 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000006463 58.0
HFD2_k127_5141484_143 BlaR1 peptidase M56 - - - 0.000005703 54.0
HFD2_k127_5141484_144 Protein of unknown function (DUF2752) - - - 0.0001123 54.0
HFD2_k127_5141484_146 Domain of unknown function (DUF5109) - - - 0.0004874 46.0
HFD2_k127_5141484_15 PFAM glycoside hydrolase, family 3 domain protein K05349 - 3.2.1.21 1.721e-247 787.0
HFD2_k127_5141484_16 Aldehyde oxidase and xanthine dehydrogenase - - - 1.481e-246 784.0
HFD2_k127_5141484_17 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 1.38e-239 760.0
HFD2_k127_5141484_18 Histidine kinase - - - 2.81e-225 746.0
HFD2_k127_5141484_19 antibiotic catabolic process - - - 2.318e-224 712.0
HFD2_k127_5141484_2 family 2 sugar binding - - - 0.0 1085.0
HFD2_k127_5141484_20 Belongs to the glycosyl hydrolase 30 family K01201 - 3.2.1.45 2.634e-221 699.0
HFD2_k127_5141484_21 polysaccharide catabolic process K01179 - 3.2.1.4 2.53e-217 693.0
HFD2_k127_5141484_22 Sodium/hydrogen exchanger family K11105 - - 2.829e-203 643.0
HFD2_k127_5141484_23 Fibronectin type III-like domain - - - 3.104e-195 651.0
HFD2_k127_5141484_24 Converts the aldose L-fucose into the corresponding ketose L-fuculose K01804 - 5.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 619.0
HFD2_k127_5141484_25 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 611.0
HFD2_k127_5141484_26 Belongs to the glycosyl hydrolase family 6 K01179,K01183 - 3.2.1.14,3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 618.0
HFD2_k127_5141484_27 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 586.0
HFD2_k127_5141484_28 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 573.0
HFD2_k127_5141484_29 (ABC) transporter K15738,K18231 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 570.0
HFD2_k127_5141484_3 metallopeptidase activity K01183 - 3.2.1.14 0.0 1069.0
HFD2_k127_5141484_30 PFAM Glycoside hydrolase, family 29 K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 563.0
HFD2_k127_5141484_31 Belongs to the purine-cytosine permease (2.A.39) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 571.0
HFD2_k127_5141484_32 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 541.0
HFD2_k127_5141484_33 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 542.0
HFD2_k127_5141484_34 PFAM amidohydrolase K01464 - 3.5.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 532.0
HFD2_k127_5141484_35 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 524.0
HFD2_k127_5141484_36 lactate racemase activity K22373 - 5.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007248 497.0
HFD2_k127_5141484_37 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 498.0
HFD2_k127_5141484_38 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 487.0
HFD2_k127_5141484_39 4 iron, 4 sulfur cluster binding K02572,K02573,K17723 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0006139,GO:0006206,GO:0006208,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016491,GO:0016651,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0048037,GO:0051536,GO:0051540,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007223 478.0
HFD2_k127_5141484_4 TonB-dependent receptor - - - 0.0 1054.0
HFD2_k127_5141484_40 polysaccharide catabolic process K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 475.0
HFD2_k127_5141484_41 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 473.0
HFD2_k127_5141484_42 xyloglucan:xyloglucosyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 477.0
HFD2_k127_5141484_43 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 469.0
HFD2_k127_5141484_44 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 456.0
HFD2_k127_5141484_45 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005713 451.0
HFD2_k127_5141484_46 Glycosyl Hydrolase Family 88 K15532 - 3.2.1.172 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006439 450.0
HFD2_k127_5141484_47 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 464.0
HFD2_k127_5141484_48 Alpha mannosidase, middle domain K01191 - 3.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 455.0
HFD2_k127_5141484_49 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 435.0
HFD2_k127_5141484_5 - - - - 0.0 1038.0
HFD2_k127_5141484_50 protein secretion K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 430.0
HFD2_k127_5141484_51 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 419.0
HFD2_k127_5141484_52 CO dehydrogenase flavoprotein C-terminal domain K13481 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008277 392.0
HFD2_k127_5141484_53 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 - 2.1.3.3,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 392.0
HFD2_k127_5141484_54 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 370.0
HFD2_k127_5141484_55 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 366.0
HFD2_k127_5141484_56 Belongs to the LDH MDH superfamily K00016 - 1.1.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 359.0
HFD2_k127_5141484_57 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 385.0
HFD2_k127_5141484_58 purine nucleotide biosynthetic process K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 372.0
HFD2_k127_5141484_59 Glycosyl Transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 362.0
HFD2_k127_5141484_6 TonB-dependent receptor - - - 5.179e-307 972.0
HFD2_k127_5141484_60 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate K01815 - 5.3.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 353.0
HFD2_k127_5141484_61 carbohydrate transport K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006135 362.0
HFD2_k127_5141484_62 PhoQ Sensor K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 366.0
HFD2_k127_5141484_63 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 351.0
HFD2_k127_5141484_64 Beta-galactosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 367.0
HFD2_k127_5141484_65 Domain of unknown function - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 355.0
HFD2_k127_5141484_66 dihydrofolate reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 337.0
HFD2_k127_5141484_67 Short-chain dehydrogenase reductase SDR K00046,K00065,K18009 - 1.1.1.127,1.1.1.304,1.1.1.69,1.1.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 331.0
HFD2_k127_5141484_68 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 336.0
HFD2_k127_5141484_69 Domain of unknown function (DUF4091) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009263 338.0
HFD2_k127_5141484_7 symporter activity K03307 - - 2.482e-304 939.0
HFD2_k127_5141484_70 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 322.0
HFD2_k127_5141484_71 Glycosyl hydrolases family 16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 320.0
HFD2_k127_5141484_72 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 319.0
HFD2_k127_5141484_73 beta-galactosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 322.0
HFD2_k127_5141484_74 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 315.0
HFD2_k127_5141484_76 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 307.0
HFD2_k127_5141484_77 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005123 336.0
HFD2_k127_5141484_78 'glutamate synthase K00266,K17722 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006208,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016491,GO:0016651,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0048037,GO:0051536,GO:0051540,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.3.1.1,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 304.0
HFD2_k127_5141484_79 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 287.0
HFD2_k127_5141484_8 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 1.042e-287 915.0
HFD2_k127_5141484_80 Amidinotransferase K01482 - 3.5.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002597 280.0
HFD2_k127_5141484_81 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001339 278.0
HFD2_k127_5141484_82 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001748 281.0
HFD2_k127_5141484_83 conserved protein (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001812 278.0
HFD2_k127_5141484_84 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002519 275.0
HFD2_k127_5141484_85 Domain of unknown function (DUF4861) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001303 275.0
HFD2_k127_5141484_86 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002404 262.0
HFD2_k127_5141484_87 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.000000000000000000000000000000000000000000000000000000000000000000000004169 253.0
HFD2_k127_5141484_88 light absorption K07255,K21700 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009058 246.0
HFD2_k127_5141484_89 phosphoesterase, PA-phosphatase related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001915 262.0
HFD2_k127_5141484_9 Belongs to the glycosyl hydrolase 3 family K05349 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0008422,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0015926,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.21 1.158e-287 905.0
HFD2_k127_5141484_90 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005096 251.0
HFD2_k127_5141484_91 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003599 248.0
HFD2_k127_5141484_92 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000227 239.0
HFD2_k127_5141484_93 Phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003424 244.0
HFD2_k127_5141484_94 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003719 237.0
HFD2_k127_5141484_95 PFAM Peptidase C11, clostripain - - - 0.0000000000000000000000000000000000000000000000000000000000000000008587 257.0
HFD2_k127_5141484_96 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.000000000000000000000000000000000000000000000000000000000000000008771 237.0
HFD2_k127_5141484_97 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000004396 248.0
HFD2_k127_5141484_98 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000001219 247.0
HFD2_k127_5141484_99 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000002714 228.0
HFD2_k127_5263145_0 PFAM glycoside hydrolase family 2 sugar binding - - - 0.0 1139.0
HFD2_k127_5263145_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1054.0
HFD2_k127_5263145_10 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 447.0
HFD2_k127_5263145_11 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 420.0
HFD2_k127_5263145_12 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008149 394.0
HFD2_k127_5263145_13 N-acetylglucosaminylinositol deacetylase activity K22136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 387.0
HFD2_k127_5263145_14 Psort location Cytoplasmic, score K01239 - 3.2.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 344.0
HFD2_k127_5263145_15 PFAM Xylose isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 346.0
HFD2_k127_5263145_16 COG3227 Zinc metalloprotease (elastase) K01400 - 3.4.24.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 354.0
HFD2_k127_5263145_17 ADP-ribosylation Crystallin J1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 330.0
HFD2_k127_5263145_18 PFAM Glycoside hydrolase 15-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008945 345.0
HFD2_k127_5263145_19 PFAM TonB-dependent Receptor Plug Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006194 338.0
HFD2_k127_5263145_2 Belongs to the IlvD Edd family K01687 - 4.2.1.9 6.558e-276 857.0
HFD2_k127_5263145_20 Aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 316.0
HFD2_k127_5263145_21 Carboxylesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 311.0
HFD2_k127_5263145_22 PFAM SMP-30 Gluconolaconase LRE-like region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 309.0
HFD2_k127_5263145_23 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 302.0
HFD2_k127_5263145_24 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 302.0
HFD2_k127_5263145_25 dioxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 285.0
HFD2_k127_5263145_26 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001566 282.0
HFD2_k127_5263145_27 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001742 283.0
HFD2_k127_5263145_28 endo-1,4-beta-xylanase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002183 291.0
HFD2_k127_5263145_29 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001775 266.0
HFD2_k127_5263145_3 Belongs to the TPP enzyme family K01652 GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681 2.2.1.6 4.825e-218 692.0
HFD2_k127_5263145_30 Flavodoxin K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000005729 258.0
HFD2_k127_5263145_31 Chalcone and stilbene synthases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002055 261.0
HFD2_k127_5263145_32 endo-1,4-beta-xylanase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005172 259.0
HFD2_k127_5263145_33 endo-1,4-beta-xylanase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001567 260.0
HFD2_k127_5263145_34 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005996 256.0
HFD2_k127_5263145_35 Trehalose utilisation K09992 - - 0.00000000000000000000000000000000000000000000000000000000000000000009121 240.0
HFD2_k127_5263145_36 TIGRFAM acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000001474 201.0
HFD2_k127_5263145_37 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000001092 209.0
HFD2_k127_5263145_38 DoxX - - - 0.0000000000000000000000000000000000000000000001262 172.0
HFD2_k127_5263145_39 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000001936 180.0
HFD2_k127_5263145_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.061e-206 653.0
HFD2_k127_5263145_40 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000002785 183.0
HFD2_k127_5263145_41 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000000000000008372 169.0
HFD2_k127_5263145_42 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000009682 169.0
HFD2_k127_5263145_43 Belongs to the peptidase S8 family K06113,K12685 - 3.2.1.99 0.00000000000000000000000000000000000009328 164.0
HFD2_k127_5263145_44 FAD binding domain - - - 0.000000000000000000000000000000000001561 153.0
HFD2_k127_5263145_45 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose K06726 - 5.4.99.62 0.0000000000000000000000000000000000035 141.0
HFD2_k127_5263145_46 Methyltransferase - - - 0.00000000000000000000000000000000001456 147.0
HFD2_k127_5263145_47 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000005881 143.0
HFD2_k127_5263145_48 Endonuclease I - - - 0.00000000000000000000004888 108.0
HFD2_k127_5263145_49 Flagellar filament outer layer protein Flaa - - - 0.00000000000000000000006524 113.0
HFD2_k127_5263145_5 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 587.0
HFD2_k127_5263145_50 cellulose binding - - - 0.000000000000000000003591 110.0
HFD2_k127_5263145_51 PFAM Uncharacterised BCR, COG1649 - - - 0.00000000000000000001305 108.0
HFD2_k127_5263145_52 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000273 95.0
HFD2_k127_5263145_53 glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.0000000000003006 76.0
HFD2_k127_5263145_54 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000001368 67.0
HFD2_k127_5263145_55 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000001865 70.0
HFD2_k127_5263145_57 Ureidoglycolate lyase - - - 0.00000007498 60.0
HFD2_k127_5263145_58 - - - - 0.00007648 55.0
HFD2_k127_5263145_6 Glycosyl hydrolase family 92 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005876 571.0
HFD2_k127_5263145_7 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 516.0
HFD2_k127_5263145_8 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 507.0
HFD2_k127_5263145_9 Glycosyl hydrolases family 35 K12308 - 3.2.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 485.0
HFD2_k127_5292825_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 9.486e-304 943.0
HFD2_k127_5292825_1 Pfam:CPSase_L_chain K01961,K01965 - 6.3.4.14,6.4.1.2,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 545.0
HFD2_k127_5292825_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000004647 148.0
HFD2_k127_5292825_3 CoA carboxylase activity K01965,K02160 - 6.4.1.3 0.000000000000000000000002936 108.0
HFD2_k127_5295099_0 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 482.0
HFD2_k127_5295099_1 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 430.0
HFD2_k127_5295099_2 polysaccharide export K01991 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000375 262.0
HFD2_k127_5295099_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000002009 273.0
HFD2_k127_5295099_4 Replication initiation and membrane attachment - - - 0.00006627 54.0
HFD2_k127_5305393_0 Phospholipase B - - - 0.0 1057.0
HFD2_k127_5305393_1 Involved in the tonB-independent uptake of proteins K07277 - - 8.463e-309 979.0
HFD2_k127_5305393_10 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 607.0
HFD2_k127_5305393_11 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 612.0
HFD2_k127_5305393_12 8-amino-7-oxononanoate synthase activity K00639,K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 599.0
HFD2_k127_5305393_13 purine nucleobase transmembrane transporter activity K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 556.0
HFD2_k127_5305393_14 PFAM N-acylglucosamine 2-epimerase K01787 - 5.1.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 554.0
HFD2_k127_5305393_15 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008997 563.0
HFD2_k127_5305393_16 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006461 548.0
HFD2_k127_5305393_17 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 531.0
HFD2_k127_5305393_18 Glycosyl hydrolase family 47 K01230,K10085 - 3.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 513.0
HFD2_k127_5305393_19 GMP synthase C terminal domain K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 512.0
HFD2_k127_5305393_2 GxGYxYP putative glycoside hydrolase C-terminal domain K03088 - - 1.513e-279 875.0
HFD2_k127_5305393_20 Sugar (and other) transporter K08138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 504.0
HFD2_k127_5305393_21 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 514.0
HFD2_k127_5305393_22 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 478.0
HFD2_k127_5305393_23 MacB-like periplasmic core domain K02004,K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 452.0
HFD2_k127_5305393_24 FtsX-like permease family K02004,K05685,K09808,K11636 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 452.0
HFD2_k127_5305393_25 lipopolysaccharide-transporting ATPase activity K07091,K11720 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 438.0
HFD2_k127_5305393_26 PFAM Peptidase family M1 K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 441.0
HFD2_k127_5305393_27 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 428.0
HFD2_k127_5305393_28 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 411.0
HFD2_k127_5305393_29 PFAM Alcohol dehydrogenase GroES domain protein K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 402.0
HFD2_k127_5305393_3 peptidase S9 prolyl oligopeptidase active site domain protein - - - 1.694e-270 861.0
HFD2_k127_5305393_30 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018 - 1.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 392.0
HFD2_k127_5305393_31 isoprenoid biosynthetic process K00805,K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.30,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 384.0
HFD2_k127_5305393_32 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009528 382.0
HFD2_k127_5305393_33 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 376.0
HFD2_k127_5305393_34 Periplasmic binding protein LacI transcriptional regulator K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 376.0
HFD2_k127_5305393_35 Periplasmic binding protein LacI transcriptional regulator K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 371.0
HFD2_k127_5305393_36 Belongs to the binding-protein-dependent transport system permease family K10440,K17203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 366.0
HFD2_k127_5305393_37 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 360.0
HFD2_k127_5305393_38 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 341.0
HFD2_k127_5305393_39 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 320.0
HFD2_k127_5305393_4 Sulfatase-modifying factor enzyme 1 - - - 1.006e-264 844.0
HFD2_k127_5305393_40 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 313.0
HFD2_k127_5305393_41 lipopolysaccharide-transporting ATPase activity K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 336.0
HFD2_k127_5305393_42 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 316.0
HFD2_k127_5305393_43 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 302.0
HFD2_k127_5305393_44 protein transport K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 294.0
HFD2_k127_5305393_45 Histidine kinase K07644 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001539 287.0
HFD2_k127_5305393_46 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003106 263.0
HFD2_k127_5305393_47 MucB/RseB N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005193 273.0
HFD2_k127_5305393_48 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07665 GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0042221,GO:0042802,GO:0046688,GO:0048518,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006045 262.0
HFD2_k127_5305393_49 Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000001273 233.0
HFD2_k127_5305393_5 bacterial-type flagellum-dependent cell motility - - - 3.229e-260 853.0
HFD2_k127_5305393_50 - - - - 0.0000000000000000000000000000000000000000000000000000000000001852 218.0
HFD2_k127_5305393_51 Binding-protein-dependent transport systems inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000001408 220.0
HFD2_k127_5305393_52 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000001694 220.0
HFD2_k127_5305393_53 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000000000000000000000001871 216.0
HFD2_k127_5305393_54 - - - - 0.0000000000000000000000000000000000000000000000000000001226 206.0
HFD2_k127_5305393_55 Belongs to the glycosyl hydrolase 13 family - - - 0.00000000000000000000000000000000000000000000000000000723 218.0
HFD2_k127_5305393_56 Polynucleotide kinase 3 phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000001726 195.0
HFD2_k127_5305393_57 Belongs to the glycosyl hydrolase 18 family K01183 - 3.2.1.14 0.00000000000000000000000000000000000000000000001023 198.0
HFD2_k127_5305393_58 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000003077 180.0
HFD2_k127_5305393_59 glucan 1,4-alpha-glucosidase activity - - - 0.00000000000000000000000000000000000000000004026 185.0
HFD2_k127_5305393_6 intracellular protein transport - - - 2.799e-254 812.0
HFD2_k127_5305393_60 AMP binding - - - 0.00000000000000000000000000000000000000002247 159.0
HFD2_k127_5305393_61 carbohydrate transport K02027 - - 0.00000000000000000000000000000000000006324 158.0
HFD2_k127_5305393_62 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000001604 149.0
HFD2_k127_5305393_63 - - - - 0.0000000000000000000000000005494 121.0
HFD2_k127_5305393_64 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.0000000000000000000000006607 117.0
HFD2_k127_5305393_65 Pkd domain containing protein - - - 0.00000000000005108 87.0
HFD2_k127_5305393_67 Disulphide bond corrector protein DsbC K04084,K06888 - 1.8.1.8 0.00000008603 63.0
HFD2_k127_5305393_68 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000006343 58.0
HFD2_k127_5305393_7 Pyruvate formate lyase-like - - - 7.226e-250 792.0
HFD2_k127_5305393_8 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 2.921e-202 651.0
HFD2_k127_5305393_9 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 7.399e-202 635.0
HFD2_k127_5360522_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1085.0
HFD2_k127_5360522_1 TonB-dependent receptor - - - 0.0 1068.0
HFD2_k127_5360522_10 Carboxypeptidase regulatory-like domain - - - 1.108e-237 773.0
HFD2_k127_5360522_100 cellular water homeostasis K05802,K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000003233 248.0
HFD2_k127_5360522_101 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000000000009087 239.0
HFD2_k127_5360522_102 Hydrogenase accessory protein HypB K03189,K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000001635 241.0
HFD2_k127_5360522_103 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000242 237.0
HFD2_k127_5360522_104 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000002978 235.0
HFD2_k127_5360522_105 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000369 237.0
HFD2_k127_5360522_106 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000008748 249.0
HFD2_k127_5360522_107 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000108 241.0
HFD2_k127_5360522_108 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.000000000000000000000000000000000000000000000000000000000000006469 227.0
HFD2_k127_5360522_109 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K00556,K03218,K03437,K15333 GO:0001510,GO:0002128,GO:0002938,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008175,GO:0008757,GO:0009020,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0106050,GO:0140098,GO:0140101,GO:1901360 2.1.1.185,2.1.1.34 0.00000000000000000000000000000000000000000000000000000000000004314 221.0
HFD2_k127_5360522_11 serine-type D-Ala-D-Ala carboxypeptidase activity K05366 - 2.4.1.129,3.4.16.4 1.586e-228 730.0
HFD2_k127_5360522_110 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000009516 220.0
HFD2_k127_5360522_111 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000009982 218.0
HFD2_k127_5360522_112 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000001573 224.0
HFD2_k127_5360522_113 Oxidoreductase molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000002278 221.0
HFD2_k127_5360522_114 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000003338 218.0
HFD2_k127_5360522_115 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000008549 221.0
HFD2_k127_5360522_116 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000004343 208.0
HFD2_k127_5360522_117 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000001007 209.0
HFD2_k127_5360522_119 PFAM biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000006867 206.0
HFD2_k127_5360522_12 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity K02372,K02535,K13599,K16363 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 3.5.1.108,4.2.1.59 1.482e-212 670.0
HFD2_k127_5360522_120 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000101 200.0
HFD2_k127_5360522_121 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000008007 200.0
HFD2_k127_5360522_122 - - - - 0.00000000000000000000000000000000000000000000000000002218 214.0
HFD2_k127_5360522_123 ribonuclease III activity K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000004146 199.0
HFD2_k127_5360522_124 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000009276 190.0
HFD2_k127_5360522_125 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000001312 201.0
HFD2_k127_5360522_126 PFAM Formiminotransferase-cyclodeaminase - - - 0.00000000000000000000000000000000000000000000000001037 187.0
HFD2_k127_5360522_127 retrograde transport, endosome to Golgi K07095 - - 0.00000000000000000000000000000000000000000000000009137 197.0
HFD2_k127_5360522_128 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000002696 186.0
HFD2_k127_5360522_129 DinB family - - - 0.0000000000000000000000000000000000000000000000008931 183.0
HFD2_k127_5360522_13 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005861 606.0
HFD2_k127_5360522_130 - - - - 0.000000000000000000000000000000000000000000000004467 186.0
HFD2_k127_5360522_131 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000002457 179.0
HFD2_k127_5360522_132 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000004845 184.0
HFD2_k127_5360522_133 GGDEF domain K03413 - - 0.0000000000000000000000000000000000000000000003236 184.0
HFD2_k127_5360522_134 nUDIX hydrolase K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000007808 171.0
HFD2_k127_5360522_135 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000105 164.0
HFD2_k127_5360522_136 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000001773 166.0
HFD2_k127_5360522_137 protein trimerization - - - 0.00000000000000000000000000000000000000000006344 175.0
HFD2_k127_5360522_138 unfolded protein binding K06142 - - 0.00000000000000000000000000000000000000000016 170.0
HFD2_k127_5360522_139 metal cluster binding K06940,K18475 - - 0.0000000000000000000000000000000000000000005871 164.0
HFD2_k127_5360522_14 lyase activity K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007811 578.0
HFD2_k127_5360522_140 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000007286 163.0
HFD2_k127_5360522_141 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.000000000000000000000000000000000000000003492 163.0
HFD2_k127_5360522_142 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000005415 162.0
HFD2_k127_5360522_143 peptide deformylase activity K01462 - 3.5.1.88 0.000000000000000000000000000000000000000005748 163.0
HFD2_k127_5360522_144 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000001108 171.0
HFD2_k127_5360522_145 - - - - 0.00000000000000000000000000000000000000004399 159.0
HFD2_k127_5360522_146 cytochrome complex assembly K02198,K02200,K04016,K04017,K04018 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564 - 0.0000000000000000000000000000000000000002412 163.0
HFD2_k127_5360522_147 Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily K09457 - 1.7.1.13 0.0000000000000000000000000000000000000004832 153.0
HFD2_k127_5360522_148 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000000008236 154.0
HFD2_k127_5360522_149 - - - - 0.000000000000000000000000000000000000003759 151.0
HFD2_k127_5360522_15 membrane organization K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 597.0
HFD2_k127_5360522_150 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000004849 160.0
HFD2_k127_5360522_151 - - - - 0.0000000000000000000000000000000000002744 156.0
HFD2_k127_5360522_152 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K13566 - 3.5.1.3 0.000000000000000000000000000000000001883 149.0
HFD2_k127_5360522_153 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000004245 151.0
HFD2_k127_5360522_154 CoA binding domain K06929 - - 0.0000000000000000000000000000000004388 135.0
HFD2_k127_5360522_155 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000001425 142.0
HFD2_k127_5360522_156 YbaB/EbfC DNA-binding family K09747 - - 0.000000000000000000000000000000001884 132.0
HFD2_k127_5360522_157 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.00000000000000000000000000000000368 134.0
HFD2_k127_5360522_158 - - - - 0.00000000000000000000000000000001262 135.0
HFD2_k127_5360522_159 methylamine metabolic process K03885,K15977 - 1.6.99.3 0.00000000000000000000000000000003027 133.0
HFD2_k127_5360522_16 methionine adenosyltransferase activity K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 562.0
HFD2_k127_5360522_160 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000003097 125.0
HFD2_k127_5360522_161 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000000001792 124.0
HFD2_k127_5360522_162 PTS HPr component phosphorylation site K11189 - - 0.00000000000000000000000000007115 117.0
HFD2_k127_5360522_163 metal-binding, possibly nucleic acid-binding protein K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000007197 123.0
HFD2_k127_5360522_164 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K07291 - 2.7.8.34 0.0000000000000000000000000009294 125.0
HFD2_k127_5360522_165 Thioredoxin - - - 0.000000000000000000000000002664 118.0
HFD2_k127_5360522_167 extracellular polysaccharide biosynthetic process K00568,K03561,K07011,K20444 - 2.1.1.222,2.1.1.64 0.00000000000000000000000002542 123.0
HFD2_k127_5360522_168 protein kinase related protein - - - 0.00000000000000000000000003263 122.0
HFD2_k127_5360522_169 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000000756 108.0
HFD2_k127_5360522_17 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 559.0
HFD2_k127_5360522_170 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000292 109.0
HFD2_k127_5360522_171 THIamine pyrophosphokinase K00949 - 2.7.6.2 0.0000000000000000000000003952 113.0
HFD2_k127_5360522_172 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000006347 114.0
HFD2_k127_5360522_173 Protein of unknown function (DUF3276) - - - 0.00000000000000000000003576 102.0
HFD2_k127_5360522_174 Transglycosylase associated protein - - - 0.00000000000000000000009594 99.0
HFD2_k127_5360522_175 Hydrogenase expression formation protein K04653 - - 0.000000000000000000000141 102.0
HFD2_k127_5360522_176 Response regulator receiver domain K07668 - - 0.0000000000000000000001944 102.0
HFD2_k127_5360522_177 Peptidase S24-like - - - 0.0000000000000000000005979 107.0
HFD2_k127_5360522_179 Heavy-metal-associated domain K08364 - - 0.0000000000000000001466 96.0
HFD2_k127_5360522_18 Flavin containing amine oxidoreductase K09835,K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,5.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 563.0
HFD2_k127_5360522_180 Phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000001094 94.0
HFD2_k127_5360522_181 Ribosomal L32p protein family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000001284 86.0
HFD2_k127_5360522_182 CHAD domain - - - 0.00000000000000002434 92.0
HFD2_k127_5360522_183 Adenylate cyclase - - - 0.00000000000000148 91.0
HFD2_k127_5360522_185 phosphohistidine phosphatase, SixA K08296 - - 0.00000000000003785 80.0
HFD2_k127_5360522_187 Glyoxalase-like domain K06996 - - 0.0000000000002137 77.0
HFD2_k127_5360522_188 response regulator - - - 0.0000000000003396 74.0
HFD2_k127_5360522_189 positive regulation of macromolecule biosynthetic process K03973 - - 0.0000000000008015 78.0
HFD2_k127_5360522_19 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 571.0
HFD2_k127_5360522_190 response regulator K07782 - - 0.000000000001221 72.0
HFD2_k127_5360522_191 outer membrane chaperone Skp (OmpH) K06142 - - 0.00000000002953 73.0
HFD2_k127_5360522_192 Domain of unknown function (DUF4340) - - - 0.0000000000359 74.0
HFD2_k127_5360522_194 Glycogen debranching enzyme - - - 0.000000000245 74.0
HFD2_k127_5360522_195 - - - - 0.000000007705 61.0
HFD2_k127_5360522_197 - - - - 0.0000001449 55.0
HFD2_k127_5360522_198 Outer membrane protein, OMP85 family K07277 - - 0.0000005982 62.0
HFD2_k127_5360522_199 Transposase - - - 0.00003994 54.0
HFD2_k127_5360522_2 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1013.0
HFD2_k127_5360522_20 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458,K14660 - 2.3.1.179,2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 553.0
HFD2_k127_5360522_200 - - - - 0.0001802 53.0
HFD2_k127_5360522_201 peptidyl-tyrosine sulfation - - - 0.0003084 50.0
HFD2_k127_5360522_202 peptidyl-tyrosine sulfation - - - 0.0008504 53.0
HFD2_k127_5360522_21 deaminase activity K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 544.0
HFD2_k127_5360522_22 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 530.0
HFD2_k127_5360522_23 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 561.0
HFD2_k127_5360522_24 Associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 512.0
HFD2_k127_5360522_25 Protein of unknown function (DUF1015) K00262 - 1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 508.0
HFD2_k127_5360522_26 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 503.0
HFD2_k127_5360522_27 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K03205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007985 533.0
HFD2_k127_5360522_28 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 509.0
HFD2_k127_5360522_29 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 495.0
HFD2_k127_5360522_3 membrane organization K03641,K07277 - - 1.51e-316 998.0
HFD2_k127_5360522_30 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000708 499.0
HFD2_k127_5360522_31 Pyrimidine nucleoside phosphorylase C-terminal domain K00756,K00758 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009482 479.0
HFD2_k127_5360522_32 Cytidylyltransferase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 474.0
HFD2_k127_5360522_33 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 486.0
HFD2_k127_5360522_34 beta-ketoacyl-acyl-carrier-protein synthase III activity K00648 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 460.0
HFD2_k127_5360522_35 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 457.0
HFD2_k127_5360522_36 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00003,K00970,K00974,K00982,K00990,K06950,K15371 - 1.1.1.3,1.4.1.2,2.7.7.19,2.7.7.42,2.7.7.59,2.7.7.72,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 469.0
HFD2_k127_5360522_37 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 445.0
HFD2_k127_5360522_38 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 444.0
HFD2_k127_5360522_39 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 433.0
HFD2_k127_5360522_4 membrane organization K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 2.701e-274 864.0
HFD2_k127_5360522_40 phosphorelay signal transduction system K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009959 431.0
HFD2_k127_5360522_41 Oligoendopeptidase f K01283,K08602 - 3.4.15.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006976 432.0
HFD2_k127_5360522_42 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 415.0
HFD2_k127_5360522_43 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 403.0
HFD2_k127_5360522_44 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006513 411.0
HFD2_k127_5360522_45 PFAM major facilitator superfamily MFS_1 K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 406.0
HFD2_k127_5360522_46 Aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 406.0
HFD2_k127_5360522_47 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006467 405.0
HFD2_k127_5360522_48 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 410.0
HFD2_k127_5360522_49 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 400.0
HFD2_k127_5360522_5 Belongs to the carbamoyltransferase HypF family K04656 - - 5.87e-273 864.0
HFD2_k127_5360522_50 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009744 396.0
HFD2_k127_5360522_51 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 387.0
HFD2_k127_5360522_52 oxidoreductase activity K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 385.0
HFD2_k127_5360522_53 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 385.0
HFD2_k127_5360522_54 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 378.0
HFD2_k127_5360522_55 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 379.0
HFD2_k127_5360522_56 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009451 368.0
HFD2_k127_5360522_57 symporter activity K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005421 385.0
HFD2_k127_5360522_58 protein (some members contain a von Willebrand factor type A (vWA) domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 363.0
HFD2_k127_5360522_59 Formiminotransferase-cyclodeaminase K00603,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 374.0
HFD2_k127_5360522_6 urocanate hydratase activity K01712 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 1.394e-270 842.0
HFD2_k127_5360522_60 [acyl-carrier-protein] S-malonyltransferase activity K00645,K15327,K15329,K15355,K15469 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 368.0
HFD2_k127_5360522_61 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007767 373.0
HFD2_k127_5360522_62 Acetokinase family K00929 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0044424,GO:0044464,GO:0047761 2.7.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007558 354.0
HFD2_k127_5360522_63 oxidoreductase activity K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 343.0
HFD2_k127_5360522_64 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 350.0
HFD2_k127_5360522_65 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 338.0
HFD2_k127_5360522_66 Outer membrane lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 368.0
HFD2_k127_5360522_67 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 356.0
HFD2_k127_5360522_68 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 341.0
HFD2_k127_5360522_69 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 331.0
HFD2_k127_5360522_7 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 8.496e-266 834.0
HFD2_k127_5360522_70 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 334.0
HFD2_k127_5360522_71 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 331.0
HFD2_k127_5360522_72 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 332.0
HFD2_k127_5360522_73 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000968 334.0
HFD2_k127_5360522_74 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 314.0
HFD2_k127_5360522_75 transferase activity, transferring alkyl or aryl (other than methyl) groups K00806,K14215,K21273 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.86,2.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 314.0
HFD2_k127_5360522_76 Bacterial phospho-glucose isomerase C-terminal SIS domain K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 317.0
HFD2_k127_5360522_77 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 315.0
HFD2_k127_5360522_78 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 310.0
HFD2_k127_5360522_79 fatty acid biosynthetic process K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 313.0
HFD2_k127_5360522_8 Belongs to the GPI family K01810 GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 7.879e-257 803.0
HFD2_k127_5360522_80 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 298.0
HFD2_k127_5360522_81 Putative methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 301.0
HFD2_k127_5360522_82 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 288.0
HFD2_k127_5360522_83 iron ion homeostasis K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 291.0
HFD2_k127_5360522_84 inositol monophosphate 1-phosphatase activity K01082,K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 291.0
HFD2_k127_5360522_85 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001477 305.0
HFD2_k127_5360522_86 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003751 289.0
HFD2_k127_5360522_87 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001772 283.0
HFD2_k127_5360522_88 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009541 297.0
HFD2_k127_5360522_89 cyclic nucleotide binding K01420,K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006871 267.0
HFD2_k127_5360522_9 TonB-dependent receptor K02014 - - 1.545e-248 791.0
HFD2_k127_5360522_90 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000001729 273.0
HFD2_k127_5360522_91 ROK family K00886 - 2.7.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000217 268.0
HFD2_k127_5360522_92 isoprenoid biosynthetic process K13787,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000008092 270.0
HFD2_k127_5360522_93 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000001437 265.0
HFD2_k127_5360522_94 BAAT / Acyl-CoA thioester hydrolase C terminal K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001883 270.0
HFD2_k127_5360522_95 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002281 278.0
HFD2_k127_5360522_96 iron ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001739 251.0
HFD2_k127_5360522_97 PFAM ABC transporter related K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000002723 246.0
HFD2_k127_5360522_98 Phosphate acetyl/butaryl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005351 248.0
HFD2_k127_5360522_99 Peptidase C26 K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000008407 242.0
HFD2_k127_5404805_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 484.0
HFD2_k127_5404805_1 PFAM AP endonuclease family 2 C terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 470.0
HFD2_k127_5404805_10 - K01992,K16919 - - 0.0000000000000000000000000000000004862 149.0
HFD2_k127_5404805_11 - K01992,K16919 - - 0.0000000000000000000000000000006568 139.0
HFD2_k127_5404805_12 - K01992,K16919 - - 0.00000000000000000000000000000362 135.0
HFD2_k127_5404805_13 Domain of unknown function (DUF3526) - - - 0.00000000000000000000000003354 124.0
HFD2_k127_5404805_14 - K01992,K16919 - - 0.0000000000000000001004 103.0
HFD2_k127_5404805_15 Trehalose utilisation - - - 0.000000000000000001469 90.0
HFD2_k127_5404805_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000003156 83.0
HFD2_k127_5404805_17 Protein of unknown function (DUF2723) - - - 0.000000000000003373 89.0
HFD2_k127_5404805_18 - K01992,K19310 - - 0.0000000000002887 84.0
HFD2_k127_5404805_19 mannose-ethanolamine phosphotransferase activity - - - 0.00000001859 66.0
HFD2_k127_5404805_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 425.0
HFD2_k127_5404805_20 Cadherin repeats. - - - 0.00000002362 63.0
HFD2_k127_5404805_3 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 415.0
HFD2_k127_5404805_4 cell adhesion involved in biofilm formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009315 387.0
HFD2_k127_5404805_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 332.0
HFD2_k127_5404805_6 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004916 291.0
HFD2_k127_5404805_7 - - - - 0.0000000000000000000000000000000000000000000000000000001183 204.0
HFD2_k127_5404805_8 Bacterial membrane protein YfhO - - - 0.00000000000000000000000000000000000000000000000000005723 212.0
HFD2_k127_5404805_9 - K01992,K16919 - - 0.0000000000000000000000000000000000000000000001986 184.0
HFD2_k127_5430340_0 Putative zinc binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 609.0
HFD2_k127_5430340_1 Domain of unknown function (DUF4910) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 604.0
HFD2_k127_5430340_2 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 504.0
HFD2_k127_5430340_3 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K00067,K01790 - 1.1.1.133,5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000004966 232.0
HFD2_k127_5430340_4 Nucleotidyl transferase K00978 - 2.7.7.33 0.000000000000000000000000000000000000003621 146.0
HFD2_k127_5430340_5 - - - - 0.0000000000000000000000000000000000003129 149.0
HFD2_k127_5482868_0 GTPase activity K03596 - - 3.276e-296 917.0
HFD2_k127_5482868_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K16881 - 2.7.7.13,5.4.2.8 1.209e-280 886.0
HFD2_k127_5482868_10 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821,K03918,K07250,K13524 - 2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22,2.6.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 550.0
HFD2_k127_5482868_11 TIGRFAM ribonuclease, Rne Rng family K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 523.0
HFD2_k127_5482868_12 porphobilinogen synthase activity K01698 GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 464.0
HFD2_k127_5482868_13 PFAM Alpha amylase, catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 467.0
HFD2_k127_5482868_14 protoporphyrinogen oxidase activity K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 448.0
HFD2_k127_5482868_15 heat shock protein binding K03686 GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005479 437.0
HFD2_k127_5482868_16 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007865 448.0
HFD2_k127_5482868_17 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 418.0
HFD2_k127_5482868_18 serine-type endopeptidase activity K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 415.0
HFD2_k127_5482868_19 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006780,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046394,GO:0046483,GO:0046501,GO:0046502,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000969 412.0
HFD2_k127_5482868_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.128e-269 836.0
HFD2_k127_5482868_20 arabinose-5-phosphate isomerase activity K01627,K03281,K06041 - 2.5.1.55,5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 392.0
HFD2_k127_5482868_21 glutamyl-tRNA reductase activity K02407,K02492 GO:0005575,GO:0005623,GO:0009288,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007673 395.0
HFD2_k127_5482868_22 protein trimerization - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 398.0
HFD2_k127_5482868_23 ATPase activity K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 371.0
HFD2_k127_5482868_24 SMART PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 385.0
HFD2_k127_5482868_25 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 381.0
HFD2_k127_5482868_26 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 364.0
HFD2_k127_5482868_27 ATPase activity K01990,K13926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 358.0
HFD2_k127_5482868_28 3-deoxy-8-phosphooctulonate synthase activity K01627 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0022607,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 343.0
HFD2_k127_5482868_29 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 336.0
HFD2_k127_5482868_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 1.769e-242 779.0
HFD2_k127_5482868_30 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 341.0
HFD2_k127_5482868_31 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 339.0
HFD2_k127_5482868_32 coproporphyrinogen oxidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 340.0
HFD2_k127_5482868_33 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009972 330.0
HFD2_k127_5482868_34 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004605 339.0
HFD2_k127_5482868_35 transport, permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 323.0
HFD2_k127_5482868_36 ferrochelatase activity K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009314,GO:0009416,GO:0009628,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0050896,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009336 312.0
HFD2_k127_5482868_37 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 306.0
HFD2_k127_5482868_38 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001804 288.0
HFD2_k127_5482868_39 Thioredoxin-like domain K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000444 287.0
HFD2_k127_5482868_4 ftsk spoiiie K03466 - - 2.663e-226 738.0
HFD2_k127_5482868_40 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002484 297.0
HFD2_k127_5482868_41 COG1691 NCAIR mutase (PurE)-related K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002485 269.0
HFD2_k127_5482868_42 signal peptide processing K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000008724 267.0
HFD2_k127_5482868_43 cytochrome complex assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002884 261.0
HFD2_k127_5482868_44 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000001536 248.0
HFD2_k127_5482868_45 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000004023 240.0
HFD2_k127_5482868_46 lipopolysaccharide binding K09774 - - 0.00000000000000000000000000000000000000000000000000000000000000003085 239.0
HFD2_k127_5482868_47 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000001536 231.0
HFD2_k127_5482868_48 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000001333 229.0
HFD2_k127_5482868_49 Belongs to the ComB family K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.0000000000000000000000000000000000000000000000000000000009946 212.0
HFD2_k127_5482868_5 Belongs to the aldehyde dehydrogenase family K00140,K22187 - 1.2.1.18,1.2.1.27 1.548e-212 670.0
HFD2_k127_5482868_50 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000009497 194.0
HFD2_k127_5482868_51 Integral membrane protein DUF92 - - - 0.000000000000000000000000000000000000000000000000125 186.0
HFD2_k127_5482868_52 DNA-directed DNA polymerase activity K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000001279 190.0
HFD2_k127_5482868_53 lysyltransferase activity K07027 - - 0.000000000000000000000000000000000000000000000001425 187.0
HFD2_k127_5482868_54 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.00000000000000000000000000000000000000000000001918 174.0
HFD2_k127_5482868_55 - - - - 0.00000000000000000000000000000000000000000000006035 179.0
HFD2_k127_5482868_56 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000002786 174.0
HFD2_k127_5482868_57 DinB family - - - 0.0000000000000000000000000000000000000000000003868 171.0
HFD2_k127_5482868_58 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K02652,K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000002009 160.0
HFD2_k127_5482868_59 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000000000000000000000002429 171.0
HFD2_k127_5482868_6 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 559.0
HFD2_k127_5482868_60 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000006092 152.0
HFD2_k127_5482868_61 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000000000006212 168.0
HFD2_k127_5482868_62 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K12733 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005681,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0032991,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0071014,GO:0071704,GO:0140096,GO:1901564,GO:1990904 5.2.1.8 0.00000000000000000000000000000000000005749 150.0
HFD2_k127_5482868_63 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000003851 143.0
HFD2_k127_5482868_64 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000001066 146.0
HFD2_k127_5482868_65 cytokinin biosynthetic process K06966 - 3.2.2.10 0.000000000000000000000000000000001162 137.0
HFD2_k127_5482868_67 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000000000000000000000000004105 137.0
HFD2_k127_5482868_68 Lipopolysaccharide-assembly, LptC-related K09774,K11719 - - 0.0000000000000000000000000001475 121.0
HFD2_k127_5482868_69 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.0000000000000000000000000001634 123.0
HFD2_k127_5482868_7 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 560.0
HFD2_k127_5482868_70 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000003473 117.0
HFD2_k127_5482868_71 TetR Family - - - 0.00000000000000000000001499 108.0
HFD2_k127_5482868_72 Putative regulatory protein - - - 0.00000000000000000004929 94.0
HFD2_k127_5482868_73 cobalamin-transporting ATPase activity K02014 - - 0.000000000000000008196 98.0
HFD2_k127_5482868_74 Helix-hairpin-helix motif K02237 - - 0.0000000000000002949 84.0
HFD2_k127_5482868_75 cellulase activity K01081,K01179,K06931 - 3.1.3.5,3.2.1.4 0.0000000000001031 85.0
HFD2_k127_5482868_76 peptidase activity, acting on L-amino acid peptides - - - 0.000000000002901 80.0
HFD2_k127_5482868_77 Cysteine-rich CPXCG - - - 0.00000000002985 66.0
HFD2_k127_5482868_78 Phosphoserine phosphatase - - - 0.000000007254 68.0
HFD2_k127_5482868_79 Protein of unknown function with HXXEE motif - - - 0.000002835 58.0
HFD2_k127_5482868_8 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 568.0
HFD2_k127_5482868_80 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.0000271 55.0
HFD2_k127_5482868_82 - - - - 0.0001122 49.0
HFD2_k127_5482868_9 acetyl-CoA hydrolase transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007695 557.0
HFD2_k127_5501437_0 - - - - 0.0 1698.0
HFD2_k127_5501437_1 Tricorn protease PDZ domain - - - 0.0 1208.0
HFD2_k127_5501437_10 beta-galactosidase activity K12308 - 3.2.1.23 1.743e-253 805.0
HFD2_k127_5501437_100 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.00000000000000000000000000000000000000000005548 167.0
HFD2_k127_5501437_101 Cupin domain - - - 0.00000000000000000000000000000000000000000008081 163.0
HFD2_k127_5501437_102 - - - - 0.0000000000000000000000000000000000000000001814 162.0
HFD2_k127_5501437_103 Squalene--hopene cyclase - - - 0.000000000000000000000000000000000000000000302 168.0
HFD2_k127_5501437_104 NADP oxidoreductase coenzyme F420-dependent - - - 0.0000000000000000000000000000000000000000008208 168.0
HFD2_k127_5501437_105 fibronectin type III domain protein - - - 0.0000000000000000000000000000000000000001623 171.0
HFD2_k127_5501437_106 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000003362 156.0
HFD2_k127_5501437_107 - - - - 0.000000000000000000000000000000000001968 160.0
HFD2_k127_5501437_108 s1 p1 nuclease - - - 0.000000000000000000000000000000000002753 154.0
HFD2_k127_5501437_109 Chalcone isomerase-like - - - 0.000000000000000000000000000000000004009 154.0
HFD2_k127_5501437_11 Beta-L-arabinofuranosidase, GH127 K09955 - - 1.13e-251 799.0
HFD2_k127_5501437_110 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000004971 138.0
HFD2_k127_5501437_111 GYD domain - - - 0.0000000000000000000000000000000001493 136.0
HFD2_k127_5501437_112 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000001062 143.0
HFD2_k127_5501437_113 Sigma-70 region 2 - - - 0.000000000000000000000000000000001983 136.0
HFD2_k127_5501437_114 glyoxalase III activity - - - 0.000000000000000000000000000000009167 134.0
HFD2_k127_5501437_115 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07226 - - 0.00000000000000000000000000000001056 132.0
HFD2_k127_5501437_116 Hydrolase, P-loop family K06925 - - 0.00000000000000000000000000000001583 142.0
HFD2_k127_5501437_117 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K11527 - 2.7.13.3 0.00000000000000000000000000000002772 138.0
HFD2_k127_5501437_118 - - - - 0.0000000000000000000000000000002043 129.0
HFD2_k127_5501437_119 positive regulation of growth rate - GO:0003674,GO:0005488,GO:0008150,GO:0010035,GO:0010038,GO:0030955,GO:0031420,GO:0035864,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896 - 0.0000000000000000000000000000003277 128.0
HFD2_k127_5501437_12 Pfam L-fucose isomerase, C-terminal domain - - - 3.175e-246 771.0
HFD2_k127_5501437_120 Phospholipid methyltransferase - - - 0.000000000000000000000000000001842 126.0
HFD2_k127_5501437_121 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000008355 132.0
HFD2_k127_5501437_122 Flagellar Assembly Protein A K09749 - - 0.00000000000000000000000000003613 130.0
HFD2_k127_5501437_123 Glycoprotease family K14742 - - 0.000000000000000000000000000134 124.0
HFD2_k127_5501437_124 LytR cell envelope-related transcriptional attenuator - - - 0.0000000000000000000000000009716 121.0
HFD2_k127_5501437_125 PFAM 4Fe-4S ferredoxin, iron-sulfur binding K00176 - 1.2.7.3 0.000000000000000000000000001004 115.0
HFD2_k127_5501437_126 ligase activity, forming carbon-carbon bonds K00627,K01960,K20140 - 2.3.1.12,6.4.1.1,6.4.1.7 0.0000000000000000000000009877 108.0
HFD2_k127_5501437_127 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000007683 112.0
HFD2_k127_5501437_128 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000001169 106.0
HFD2_k127_5501437_129 Sigma-54 interaction domain K02584 - - 0.00000000000000007471 87.0
HFD2_k127_5501437_13 Glycosyl hydrolases family 38 N-terminal domain - - - 5.764e-244 794.0
HFD2_k127_5501437_130 outer membrane protein protective antigen - - - 0.0000000000000003718 90.0
HFD2_k127_5501437_131 Biotin-requiring enzyme - - - 0.000000000000001707 79.0
HFD2_k127_5501437_132 peptidyl-tyrosine sulfation - - - 0.000000000000004252 89.0
HFD2_k127_5501437_133 Belongs to the peptidase S8 family - - - 0.0000000000001895 83.0
HFD2_k127_5501437_135 - - - - 0.00000000001814 76.0
HFD2_k127_5501437_136 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K11630,K19078 - - 0.00000000003305 73.0
HFD2_k127_5501437_137 peptidylprolyl isomerase K03769 - 5.2.1.8 0.0000001954 64.0
HFD2_k127_5501437_139 Putative zinc-finger - - - 0.0002978 51.0
HFD2_k127_5501437_14 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 8.462e-244 765.0
HFD2_k127_5501437_140 DNA-binding protein - - - 0.0009967 46.0
HFD2_k127_5501437_15 serine-type peptidase activity K06978 - - 1.132e-227 740.0
HFD2_k127_5501437_16 Domain of unknown function (DUF5107) - - - 1.058e-225 735.0
HFD2_k127_5501437_17 tartrate metabolic process K01676,K01678 - 4.2.1.2 7.178e-225 711.0
HFD2_k127_5501437_18 phosphorelay signal transduction system - - - 2.698e-215 680.0
HFD2_k127_5501437_19 arginyl-tRNA aminoacylation K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 1.933e-198 634.0
HFD2_k127_5501437_2 serine-type peptidase activity K08676 - - 0.0 1098.0
HFD2_k127_5501437_20 Protein of unknown function (DUF2961) - - - 1.939e-198 623.0
HFD2_k127_5501437_21 Belongs to the glycosyl hydrolase 31 family - - - 1.034e-194 641.0
HFD2_k127_5501437_22 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 623.0
HFD2_k127_5501437_23 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 618.0
HFD2_k127_5501437_24 Sodium:sulfate symporter transmembrane region K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008517 563.0
HFD2_k127_5501437_25 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 555.0
HFD2_k127_5501437_27 siderophore transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 529.0
HFD2_k127_5501437_28 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 512.0
HFD2_k127_5501437_29 PFAM RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 501.0
HFD2_k127_5501437_3 - - - - 0.0 1027.0
HFD2_k127_5501437_30 PFAM aldo keto reductase K19265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 495.0
HFD2_k127_5501437_31 POT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 494.0
HFD2_k127_5501437_32 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 491.0
HFD2_k127_5501437_33 peptide catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 500.0
HFD2_k127_5501437_34 Na transporting methylmalonyl-CoA oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006477 471.0
HFD2_k127_5501437_35 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 480.0
HFD2_k127_5501437_36 ATPase activity K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000729 470.0
HFD2_k127_5501437_37 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008381 466.0
HFD2_k127_5501437_38 BNR repeat-like domain K01186 - 3.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 456.0
HFD2_k127_5501437_39 TIGRFAM YidE YbjL duplication K07085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 461.0
HFD2_k127_5501437_4 N-Acetylmuramoyl-L-alanine amidase - - - 8.246e-306 970.0
HFD2_k127_5501437_40 Periplasmic binding protein domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 439.0
HFD2_k127_5501437_41 phosphoglucosamine mutase activity K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 454.0
HFD2_k127_5501437_42 GHMP kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005336 439.0
HFD2_k127_5501437_43 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 445.0
HFD2_k127_5501437_44 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 432.0
HFD2_k127_5501437_45 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 426.0
HFD2_k127_5501437_46 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 422.0
HFD2_k127_5501437_47 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 426.0
HFD2_k127_5501437_48 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008153 419.0
HFD2_k127_5501437_49 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 413.0
HFD2_k127_5501437_5 Alpha amylase, C-terminal all-beta domain K00700 - 2.4.1.18 1.609e-285 896.0
HFD2_k127_5501437_50 PFAM TonB-dependent Receptor Plug Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 422.0
HFD2_k127_5501437_51 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 388.0
HFD2_k127_5501437_52 1-aminocyclopropane-1-carboxylate deaminase K01505,K05396 - 3.5.99.7,4.4.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 356.0
HFD2_k127_5501437_53 xylan catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 355.0
HFD2_k127_5501437_54 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 374.0
HFD2_k127_5501437_55 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 339.0
HFD2_k127_5501437_56 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 322.0
HFD2_k127_5501437_57 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 336.0
HFD2_k127_5501437_58 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005876 329.0
HFD2_k127_5501437_59 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 325.0
HFD2_k127_5501437_6 Belongs to the peptidase S8 family - - - 2.102e-281 908.0
HFD2_k127_5501437_60 Enoyl-CoA hydratase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 318.0
HFD2_k127_5501437_61 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 323.0
HFD2_k127_5501437_62 helix_turn _helix lactose operon repressor K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 317.0
HFD2_k127_5501437_63 beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 311.0
HFD2_k127_5501437_64 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 299.0
HFD2_k127_5501437_65 polysaccharide catabolic process K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 298.0
HFD2_k127_5501437_66 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 299.0
HFD2_k127_5501437_67 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008319 294.0
HFD2_k127_5501437_68 dioxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 292.0
HFD2_k127_5501437_69 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001815 284.0
HFD2_k127_5501437_7 TonB-dependent receptor - - - 4.344e-278 883.0
HFD2_k127_5501437_70 Cytidylyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007948 280.0
HFD2_k127_5501437_71 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate K03473 - 1.1.1.290 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001054 283.0
HFD2_k127_5501437_72 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001927 263.0
HFD2_k127_5501437_73 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009545 264.0
HFD2_k127_5501437_74 regulation of microtubule-based process K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003636 265.0
HFD2_k127_5501437_75 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003246 273.0
HFD2_k127_5501437_76 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000006888 256.0
HFD2_k127_5501437_77 Pfam:DUF1498 K09988 - 5.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000003681 240.0
HFD2_k127_5501437_78 Two component transcriptional regulator, winged helix family K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000003322 235.0
HFD2_k127_5501437_79 Pseudouridine synthase K06179,K06180 - 5.4.99.23,5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000005598 231.0
HFD2_k127_5501437_8 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01848 - 5.4.99.2 6.936e-259 807.0
HFD2_k127_5501437_80 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000008381 224.0
HFD2_k127_5501437_81 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000003736 224.0
HFD2_k127_5501437_82 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000000000000000000000000000000000007586 229.0
HFD2_k127_5501437_83 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000002356 223.0
HFD2_k127_5501437_84 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000007056 212.0
HFD2_k127_5501437_85 methylmalonyl-CoA epimerase K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000000000002068 205.0
HFD2_k127_5501437_86 TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000000000000002117 205.0
HFD2_k127_5501437_87 ferric iron binding K02217,K22336 GO:0001666,GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0030312,GO:0033212,GO:0033214,GO:0036293,GO:0042592,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051235,GO:0051238,GO:0051409,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070482,GO:0071944,GO:0097577,GO:0098771 1.16.3.1,1.16.3.2 0.00000000000000000000000000000000000000000000000000000004391 201.0
HFD2_k127_5501437_88 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000001432 205.0
HFD2_k127_5501437_89 ZIP Zinc transporter K07238,K16267 - - 0.0000000000000000000000000000000000000000000000000000005548 201.0
HFD2_k127_5501437_9 Carboxyl transferase domain - - - 1.724e-254 797.0
HFD2_k127_5501437_90 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000000583 196.0
HFD2_k127_5501437_91 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000000001472 190.0
HFD2_k127_5501437_92 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000004581 197.0
HFD2_k127_5501437_93 von Willebrand factor type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000333 199.0
HFD2_k127_5501437_94 Ser-tRNA(Ala) hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000547 185.0
HFD2_k127_5501437_95 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000001619 196.0
HFD2_k127_5501437_96 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000001734 183.0
HFD2_k127_5501437_97 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000001453 184.0
HFD2_k127_5501437_98 arabinogalactan endo-1,4-beta-galactosidase activity - - - 0.00000000000000000000000000000000000000000000006984 195.0
HFD2_k127_5501437_99 AMMECR1 K09141 - - 0.00000000000000000000000000000000000000000001846 171.0
HFD2_k127_5593824_0 carbohydrate binding K00702 - 2.4.1.20 0.0 1279.0
HFD2_k127_5593824_1 Tricorn protease homolog - - - 0.0 1273.0
HFD2_k127_5593824_10 Major facilitator Superfamily K03292,K16248 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 574.0
HFD2_k127_5593824_11 2-epimerase K16213 - 5.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 522.0
HFD2_k127_5593824_12 2-epimerase K16213 - 5.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 515.0
HFD2_k127_5593824_13 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 523.0
HFD2_k127_5593824_14 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 490.0
HFD2_k127_5593824_15 Beta-galactosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008366 502.0
HFD2_k127_5593824_16 major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 467.0
HFD2_k127_5593824_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 439.0
HFD2_k127_5593824_18 Pectate lyase superfamily protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 432.0
HFD2_k127_5593824_19 ribonuclease inhibitor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 398.0
HFD2_k127_5593824_2 carbohydrate binding K00702 - 2.4.1.20 0.0 1186.0
HFD2_k127_5593824_20 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 392.0
HFD2_k127_5593824_21 polysaccharide catabolic process K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 362.0
HFD2_k127_5593824_22 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 307.0
HFD2_k127_5593824_23 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000001139 213.0
HFD2_k127_5593824_24 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000004232 206.0
HFD2_k127_5593824_25 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000001651 132.0
HFD2_k127_5593824_26 - - - - 0.0000000000000000000000000007281 128.0
HFD2_k127_5593824_27 hydrolase activity, hydrolyzing O-glycosyl compounds K01337 - 3.4.21.50 0.0000000000000000000002113 111.0
HFD2_k127_5593824_28 SnoaL-like domain - - - 0.0000000000000009786 87.0
HFD2_k127_5593824_29 methylglyoxal synthase K01734 - 4.2.3.3 0.00000000000009752 75.0
HFD2_k127_5593824_3 TonB-dependent receptor - - - 3.35e-300 951.0
HFD2_k127_5593824_4 symporter activity - - - 5.167e-233 738.0
HFD2_k127_5593824_5 nucleotide catabolic process - - - 1.645e-224 724.0
HFD2_k127_5593824_6 beta-galactosidase activity K05970 - 3.1.1.53 1.873e-224 715.0
HFD2_k127_5593824_7 transferase activity, transferring glycosyl groups K16212 - 2.4.1.281 2.789e-195 617.0
HFD2_k127_5593824_8 transferase activity, transferring glycosyl groups K18785 - 2.4.1.319,2.4.1.320 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 591.0
HFD2_k127_5593824_9 alpha-galactosidase K07407 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004557,GO:0005975,GO:0005976,GO:0006080,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044238,GO:0051069,GO:0051682,GO:0071704,GO:1901575 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 595.0
HFD2_k127_5855823_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1279.0
HFD2_k127_5855823_1 COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and K03182 - 4.1.1.98 1.234e-229 731.0
HFD2_k127_5855823_10 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 396.0
HFD2_k127_5855823_11 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 368.0
HFD2_k127_5855823_12 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 366.0
HFD2_k127_5855823_13 Amino acid kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 345.0
HFD2_k127_5855823_14 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 347.0
HFD2_k127_5855823_15 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 336.0
HFD2_k127_5855823_16 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 332.0
HFD2_k127_5855823_17 TIGRFAM MazG family protein K02428,K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 297.0
HFD2_k127_5855823_18 3-dehydroquinate dehydratase activity K00014,K03785,K13832 GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009712,GO:0009713,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018958,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0042537,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046189,GO:0046278,GO:0046279,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.1.25,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 300.0
HFD2_k127_5855823_19 competence protein COMEC K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004835 302.0
HFD2_k127_5855823_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 2.332e-210 666.0
HFD2_k127_5855823_20 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001006 276.0
HFD2_k127_5855823_21 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002781 272.0
HFD2_k127_5855823_22 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004592 267.0
HFD2_k127_5855823_23 Metalloenzyme superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001024 267.0
HFD2_k127_5855823_24 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000004306 269.0
HFD2_k127_5855823_25 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006305 258.0
HFD2_k127_5855823_26 Putative RNA methylase family UPF0020 K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000007864 257.0
HFD2_k127_5855823_27 amino acid-binding ACT domain protein K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000273 238.0
HFD2_k127_5855823_28 PFAM HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000001383 231.0
HFD2_k127_5855823_29 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000001054 216.0
HFD2_k127_5855823_3 cyclic 2,3-diphosphoglycerate synthetase activity K05716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 598.0
HFD2_k127_5855823_30 4-hydroxybenzoate polyprenyltransferase K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000001043 207.0
HFD2_k127_5855823_31 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000006782 180.0
HFD2_k127_5855823_32 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000005934 191.0
HFD2_k127_5855823_33 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000005922 177.0
HFD2_k127_5855823_34 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000001526 168.0
HFD2_k127_5855823_35 Prephenate dehydrogenase K00210 - 1.3.1.12 0.000000000000000000000000000000000000000009321 164.0
HFD2_k127_5855823_36 Putative ATP-binding cassette K01992 - - 0.000000000000000000000000000000003154 147.0
HFD2_k127_5855823_37 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K01612,K03182,K16874 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 4.1.1.61,4.1.1.98 0.000000000000000000000000000000004698 138.0
HFD2_k127_5855823_38 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000002866 127.0
HFD2_k127_5855823_39 positive regulation of growth rate - - - 0.0000000000000000000000000002168 126.0
HFD2_k127_5855823_4 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 496.0
HFD2_k127_5855823_40 Tryptophanyl-tRNA synthetase K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.000000000000000000000000006593 111.0
HFD2_k127_5855823_41 nUDIX hydrolase K01515,K08310 - 3.6.1.13,3.6.1.67 0.0000000000000000000005592 101.0
HFD2_k127_5855823_42 ABC-type branched-chain amino acid transport K07121 - - 0.00000000000006272 85.0
HFD2_k127_5855823_44 Tetratricopeptide repeat - - - 0.0000004683 60.0
HFD2_k127_5855823_5 phosphate starvation-inducible protein PhoH K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 439.0
HFD2_k127_5855823_6 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 435.0
HFD2_k127_5855823_7 serine-type endopeptidase activity K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 427.0
HFD2_k127_5855823_8 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007327 417.0
HFD2_k127_5855823_9 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007437 391.0
HFD2_k127_5887886_0 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 7.066e-318 993.0
HFD2_k127_5887886_1 peptidase S9 prolyl oligopeptidase active site K01278 - 3.4.14.5 6.804e-266 835.0
HFD2_k127_5887886_10 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 496.0
HFD2_k127_5887886_11 malonyl-CoA biosynthetic process K01962,K01963 GO:0001676,GO:0003674,GO:0003824,GO:0003989,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0042759,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494,GO:1990234 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 485.0
HFD2_k127_5887886_12 translation release factor activity K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 469.0
HFD2_k127_5887886_13 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 435.0
HFD2_k127_5887886_14 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 439.0
HFD2_k127_5887886_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 437.0
HFD2_k127_5887886_16 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 424.0
HFD2_k127_5887886_17 NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 421.0
HFD2_k127_5887886_18 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 423.0
HFD2_k127_5887886_19 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 432.0
HFD2_k127_5887886_2 - - - - 4.103e-233 744.0
HFD2_k127_5887886_20 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009664 410.0
HFD2_k127_5887886_21 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 387.0
HFD2_k127_5887886_22 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005644 393.0
HFD2_k127_5887886_23 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 381.0
HFD2_k127_5887886_24 extracellular polysaccharide biosynthetic process K07011,K16554,K20998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 381.0
HFD2_k127_5887886_25 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007327 380.0
HFD2_k127_5887886_26 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 352.0
HFD2_k127_5887886_27 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 344.0
HFD2_k127_5887886_28 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 336.0
HFD2_k127_5887886_29 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008314 322.0
HFD2_k127_5887886_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 2.794e-214 680.0
HFD2_k127_5887886_30 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 325.0
HFD2_k127_5887886_31 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 315.0
HFD2_k127_5887886_32 Domain of unknown function (DUF4432) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 323.0
HFD2_k127_5887886_33 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 307.0
HFD2_k127_5887886_34 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 301.0
HFD2_k127_5887886_35 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 301.0
HFD2_k127_5887886_36 quinolinate catabolic process K00278,K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 1.4.3.16,2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 290.0
HFD2_k127_5887886_37 Protein of unknown function (DUF1385) K09153 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 290.0
HFD2_k127_5887886_38 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000028 284.0
HFD2_k127_5887886_39 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001242 278.0
HFD2_k127_5887886_4 Heparinase II/III-like protein - - - 2.996e-211 675.0
HFD2_k127_5887886_40 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001524 283.0
HFD2_k127_5887886_41 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001344 285.0
HFD2_k127_5887886_42 Transcriptional regulator sugar kinase K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001087 274.0
HFD2_k127_5887886_43 polysaccharide export K01991 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001464 277.0
HFD2_k127_5887886_44 transferase activity, transferring glycosyl groups K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001399 259.0
HFD2_k127_5887886_45 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000042 250.0
HFD2_k127_5887886_46 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001163 259.0
HFD2_k127_5887886_47 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000004974 250.0
HFD2_k127_5887886_48 methionine synthase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000001272 245.0
HFD2_k127_5887886_49 RmlD substrate binding domain K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000003169 241.0
HFD2_k127_5887886_5 Glycosyl Hydrolase Family 88 - - - 7.011e-210 663.0
HFD2_k127_5887886_50 Fumarylacetoacetate (FAA) hydrolase K01826 - 5.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000002948 234.0
HFD2_k127_5887886_51 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000003651 236.0
HFD2_k127_5887886_52 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000003018 230.0
HFD2_k127_5887886_53 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000005696 219.0
HFD2_k127_5887886_54 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000001257 211.0
HFD2_k127_5887886_55 TIGRFAM dihydroorotate dehydrogenase family protein K00226,K17723 - 1.3.1.1,1.3.98.1 0.0000000000000000000000000000000000000000000000000000000001309 216.0
HFD2_k127_5887886_56 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K11991 GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.1,3.5.4.33 0.00000000000000000000000000000000000000000000000000000000056 214.0
HFD2_k127_5887886_57 Glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000002434 209.0
HFD2_k127_5887886_58 Trehalase K01194 - 3.2.1.28 0.00000000000000000000000000000000000000000000000000000008353 214.0
HFD2_k127_5887886_59 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.0000000000000000000000000000000000000000000000000000417 192.0
HFD2_k127_5887886_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007446 612.0
HFD2_k127_5887886_60 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000003413 188.0
HFD2_k127_5887886_61 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.0000000000000000000000000000000000000000000000008114 187.0
HFD2_k127_5887886_62 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000000000000000000001367 188.0
HFD2_k127_5887886_63 PFAM glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000002858 187.0
HFD2_k127_5887886_64 cellulose binding - - - 0.0000000000000000000000000000000000000000004874 171.0
HFD2_k127_5887886_65 Belongs to the carbohydrate kinase PfkB family K00882,K00917,K16370 - 2.7.1.11,2.7.1.144,2.7.1.56 0.00000000000000000000000000000000000000000156 169.0
HFD2_k127_5887886_66 ApaG domain K06195 - - 0.0000000000000000000000000000000000000009613 151.0
HFD2_k127_5887886_67 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000008126 151.0
HFD2_k127_5887886_68 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000128 147.0
HFD2_k127_5887886_69 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000001448 145.0
HFD2_k127_5887886_7 Alpha mannosidase, middle domain K01191,K15524,K16869 GO:0003674,GO:0003824,GO:0004553,GO:0004559,GO:0005975,GO:0005996,GO:0006013,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015923,GO:0016787,GO:0016798,GO:0019318,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0071704,GO:1901135,GO:1901564 2.3.1.204,3.2.1.170,3.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007376 593.0
HFD2_k127_5887886_70 helix_turn_helix isocitrate lyase regulation K13641 - - 0.000000000000000000000000000000001185 140.0
HFD2_k127_5887886_71 - - - - 0.000000000000000000000000000000002117 141.0
HFD2_k127_5887886_72 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000002337 135.0
HFD2_k127_5887886_73 Thioesterase K07107 - - 0.00000000000000000000000000002335 128.0
HFD2_k127_5887886_74 Putative cyclase - - - 0.0000000000000000000000000002596 123.0
HFD2_k127_5887886_75 Carbon-nitrogen hydrolase - - - 0.0000000000000000000004862 111.0
HFD2_k127_5887886_76 - - - - 0.000000000000000004147 95.0
HFD2_k127_5887886_77 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.00000000000000009679 86.0
HFD2_k127_5887886_78 amidohydrolase K07045 - - 0.000000000000228 84.0
HFD2_k127_5887886_79 Glycosyl transferases group 1 - - - 0.0000000000002371 82.0
HFD2_k127_5887886_8 undecaprenyl-phosphate glucose phosphotransferase activity K05946,K21303 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016780,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046402,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.187,2.7.8.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 516.0
HFD2_k127_5887886_80 Belongs to the UPF0434 family K09791 - - 0.0000000000004556 71.0
HFD2_k127_5887886_81 4Fe-4S binding domain - - - 0.00000000001183 70.0
HFD2_k127_5887886_82 COG3387 Glucoamylase and related glycosyl hydrolases - - - 0.0000000001552 74.0
HFD2_k127_5887886_9 undecaprenyl-phosphate glucose phosphotransferase activity K03606,K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 524.0
HFD2_k127_6158299_0 homoserine kinase activity K02204 - 2.7.1.39 0.0 1265.0
HFD2_k127_6158299_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000001463 128.0
HFD2_k127_6158299_2 - - - - 0.000000000000000000000003812 118.0
HFD2_k127_6158299_3 Curli production assembly/transport component CsgG - - - 0.00001912 56.0
HFD2_k127_6199367_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.664e-285 891.0
HFD2_k127_6199367_1 Protein kinase domain K12132 - 2.7.11.1 2.505e-260 833.0
HFD2_k127_6199367_2 Metalloenzyme superfamily - - - 0.00000000000000000000000000000000000000000000000005306 196.0
HFD2_k127_6199367_4 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000001141 133.0
HFD2_k127_6199367_5 pectinesterase activity - - - 0.00000000000000000000008169 116.0
HFD2_k127_6199367_6 peptidase activity, acting on L-amino acid peptides K20276,K21449 - - 0.000000000000000001071 100.0
HFD2_k127_6199367_7 Protein of unknown function (DUF3788) - - - 0.00000000000000005732 86.0
HFD2_k127_6199367_8 amine dehydrogenase activity - - - 0.00000000000007666 86.0
HFD2_k127_6199367_9 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.0000002278 55.0
HFD2_k127_6258117_0 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 3.49e-233 759.0
HFD2_k127_6258117_1 COGs COG4299 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 322.0
HFD2_k127_6258117_2 Permease K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 293.0
HFD2_k127_6258117_3 Sugar ABC transporter permease K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 300.0
HFD2_k127_6258117_4 helix_turn _helix lactose operon repressor K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001988 280.0
HFD2_k127_6258117_5 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001041 262.0
HFD2_k127_6258117_6 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000000000000000000000000000000000000000001904 238.0
HFD2_k127_6283835_0 Glycosyl-hydrolase 97 C-terminal, oligomerisation - - - 9e-251 789.0
HFD2_k127_6283835_1 PFAM Glycosyl Hydrolase Family 88 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009028 547.0
HFD2_k127_6283835_2 Heparinase II/III-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 505.0
HFD2_k127_6283835_3 regulation of single-species biofilm formation - GO:0008150,GO:0043900,GO:0050789,GO:0050794,GO:0065007,GO:1900190 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003184 277.0
HFD2_k127_6283835_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001016 241.0
HFD2_k127_6283835_5 PFAM Uncharacterised BCR, COG1649 K01186,K01197,K05988,K11931,K18197 - 3.2.1.11,3.2.1.18,3.2.1.35,4.2.2.23 0.000000000000000000000000000004001 137.0
HFD2_k127_6283835_6 RNA polymerase sigma-70 factor K03088 - - 0.0000000001746 64.0
HFD2_k127_6283835_7 - - - - 0.000000015 60.0
HFD2_k127_6283835_8 Domain of unknown function (DUF932) - - - 0.0001577 53.0
HFD2_k127_6283835_9 hydrolase, family 65, central catalytic - - - 0.0006343 43.0
HFD2_k127_6426010_0 Carboxypeptidase regulatory-like domain - - - 0.0 1076.0
HFD2_k127_6426010_1 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 482.0
HFD2_k127_6426010_2 - - - - 0.00000000000000000000000000007636 121.0
HFD2_k127_6428335_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1406.0
HFD2_k127_6428335_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0 1360.0
HFD2_k127_6428335_10 Oligopeptide transporter OPT - - - 1.381e-235 750.0
HFD2_k127_6428335_100 L-methionine salvage from methylthioadenosine K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000005417 186.0
HFD2_k127_6428335_101 PFAM Glycosyl transferase, group 1 K12996 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.00000000000000000000000000000000000000000000000006234 191.0
HFD2_k127_6428335_102 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000004078 191.0
HFD2_k127_6428335_103 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000004926 180.0
HFD2_k127_6428335_104 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000003359 179.0
HFD2_k127_6428335_105 Endoribonuclease L-PSP K09021,K09022 GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019740,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.99.10 0.0000000000000000000000000000000000000000002788 164.0
HFD2_k127_6428335_106 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000002728 173.0
HFD2_k127_6428335_107 COG494 NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair General function prediction only K01515 - 3.6.1.13 0.000000000000000000000000000000000000000003143 161.0
HFD2_k127_6428335_108 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000006123 163.0
HFD2_k127_6428335_109 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000396 157.0
HFD2_k127_6428335_11 Trehalose-phosphatase K16055 - 2.4.1.15,3.1.3.12 3.295e-222 714.0
HFD2_k127_6428335_110 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000004226 150.0
HFD2_k127_6428335_111 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000004731 152.0
HFD2_k127_6428335_112 - - - - 0.00000000000000000000000000000000002917 146.0
HFD2_k127_6428335_113 cellulose binding - - - 0.0000000000000000000000000000000000641 147.0
HFD2_k127_6428335_114 ComF family K00764 - 2.4.2.14 0.000000000000000000000000000000004796 137.0
HFD2_k127_6428335_115 cysteine-type peptidase activity K13694,K13695 GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0006022,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009254,GO:0016787,GO:0019538,GO:0030203,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901564 3.4.17.13 0.000000000000000000000000000000007538 137.0
HFD2_k127_6428335_116 Transposase IS200 like - - - 0.00000000000000000000000000000007938 132.0
HFD2_k127_6428335_117 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000271 128.0
HFD2_k127_6428335_119 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000002728 98.0
HFD2_k127_6428335_12 Carbon starvation protein K06200 - - 9e-222 704.0
HFD2_k127_6428335_120 SMART PAS domain containing protein - - - 0.000000000000000000000375 105.0
HFD2_k127_6428335_121 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000001141 98.0
HFD2_k127_6428335_122 nuclease activity K07460 - - 0.000000000000000000009067 98.0
HFD2_k127_6428335_123 Belongs to the peptidase S8 family - - - 0.000000000000000000009176 102.0
HFD2_k127_6428335_124 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.000000000000000004429 89.0
HFD2_k127_6428335_126 - - - - 0.0000000000000002705 81.0
HFD2_k127_6428335_127 protein secretion K03116,K03117 - - 0.0000000000000005648 79.0
HFD2_k127_6428335_128 Polysaccharide biosynthesis protein - - - 0.000000000000148 83.0
HFD2_k127_6428335_129 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000002665 68.0
HFD2_k127_6428335_13 Amino acid permease - - - 1.795e-214 682.0
HFD2_k127_6428335_130 - - - - 0.000000000002724 74.0
HFD2_k127_6428335_131 Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000001867 77.0
HFD2_k127_6428335_132 Predicted membrane protein (DUF2339) - - - 0.00000000009835 74.0
HFD2_k127_6428335_134 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K11991 GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.1,3.5.4.33 0.0001026 48.0
HFD2_k127_6428335_14 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 1.247e-208 677.0
HFD2_k127_6428335_15 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 617.0
HFD2_k127_6428335_16 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 626.0
HFD2_k127_6428335_17 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 604.0
HFD2_k127_6428335_18 TIGRFAM aminoacyl-histidine dipeptidase K01270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 583.0
HFD2_k127_6428335_19 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K01876,K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 580.0
HFD2_k127_6428335_2 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K18930 - - 0.0 1127.0
HFD2_k127_6428335_20 succinyl-diaminopimelate desuccinylase activity K01436,K01438,K01439 - 3.5.1.16,3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 574.0
HFD2_k127_6428335_21 PFAM glycosyl transferase group 1 K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 557.0
HFD2_k127_6428335_22 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 533.0
HFD2_k127_6428335_23 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 533.0
HFD2_k127_6428335_24 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 530.0
HFD2_k127_6428335_25 phosphoglycerate kinase activity K00927,K01803 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 526.0
HFD2_k127_6428335_26 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 522.0
HFD2_k127_6428335_27 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009481 529.0
HFD2_k127_6428335_28 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K14441 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 517.0
HFD2_k127_6428335_29 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 512.0
HFD2_k127_6428335_3 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 5.707e-306 953.0
HFD2_k127_6428335_30 galactose-1-phosphate K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 473.0
HFD2_k127_6428335_31 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009967 458.0
HFD2_k127_6428335_32 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 449.0
HFD2_k127_6428335_33 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 443.0
HFD2_k127_6428335_34 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion K01057,K02564 GO:0003674,GO:0003824,GO:0004342,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0006044,GO:0006046,GO:0006047,GO:0006048,GO:0006054,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016054,GO:0016787,GO:0016853,GO:0016860,GO:0016861,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0019239,GO:0019262,GO:0019438,GO:0019752,GO:0034641,GO:0034654,GO:0042737,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046348,GO:0046349,GO:0046395,GO:0046483,GO:0055086,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901362,GO:1901575,GO:1901576 3.1.1.31,3.5.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008184 436.0
HFD2_k127_6428335_35 phosphopentomutase activity K01839 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008973,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 5.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 442.0
HFD2_k127_6428335_36 phosphate ion binding K02040 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009314,GO:0009628,GO:0009987,GO:0010921,GO:0015698,GO:0019220,GO:0019222,GO:0030288,GO:0030313,GO:0031323,GO:0031975,GO:0033554,GO:0035303,GO:0042301,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0065007,GO:0065009 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 437.0
HFD2_k127_6428335_37 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000853 424.0
HFD2_k127_6428335_38 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009461 427.0
HFD2_k127_6428335_39 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 406.0
HFD2_k127_6428335_4 nucleotide-excision repair K03702,K08999 GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 1.242e-287 897.0
HFD2_k127_6428335_40 inorganic phosphate transmembrane transporter activity K02037,K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 393.0
HFD2_k127_6428335_41 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000708 397.0
HFD2_k127_6428335_42 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 387.0
HFD2_k127_6428335_43 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 377.0
HFD2_k127_6428335_44 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity K00057 GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 375.0
HFD2_k127_6428335_45 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007156 387.0
HFD2_k127_6428335_46 inorganic phosphate transmembrane transporter activity K02037,K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 372.0
HFD2_k127_6428335_47 Aldo/keto reductase family K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 370.0
HFD2_k127_6428335_48 ATPase-coupled phosphate ion transmembrane transporter activity K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 357.0
HFD2_k127_6428335_49 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 357.0
HFD2_k127_6428335_5 Carbamoyltransferase C-terminus K00612 - - 3.412e-284 883.0
HFD2_k127_6428335_50 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 349.0
HFD2_k127_6428335_51 membrane organization K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 362.0
HFD2_k127_6428335_52 tRNA synthetase class II K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 358.0
HFD2_k127_6428335_53 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 351.0
HFD2_k127_6428335_54 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 349.0
HFD2_k127_6428335_55 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 344.0
HFD2_k127_6428335_56 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 338.0
HFD2_k127_6428335_57 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 347.0
HFD2_k127_6428335_58 PFAM Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009238 331.0
HFD2_k127_6428335_59 regulation of microtubule-based process K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 336.0
HFD2_k127_6428335_6 synthetase (ADP forming), alpha K01905,K22224 - 6.2.1.13 2.321e-281 885.0
HFD2_k127_6428335_60 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 328.0
HFD2_k127_6428335_61 methenyltetrahydrofolate cyclohydrolase activity K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 323.0
HFD2_k127_6428335_62 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 310.0
HFD2_k127_6428335_63 triose-phosphate isomerase activity K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 304.0
HFD2_k127_6428335_64 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 301.0
HFD2_k127_6428335_65 Belongs to the glycosyl hydrolase 2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 318.0
HFD2_k127_6428335_66 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 291.0
HFD2_k127_6428335_67 proline dehydrogenase activity K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 302.0
HFD2_k127_6428335_68 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity K02029,K02030,K09769 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009552 289.0
HFD2_k127_6428335_69 Nucleoside recognition K06373,K06374 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001364 291.0
HFD2_k127_6428335_7 ammonia-lyase activity K01745 - 4.3.1.3 8.723e-267 829.0
HFD2_k127_6428335_70 translation initiation factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000254 289.0
HFD2_k127_6428335_71 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002713 286.0
HFD2_k127_6428335_72 Alpha/beta hydrolase family K01175 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0016790,GO:0044424,GO:0044444,GO:0044464,GO:0052689 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001215 276.0
HFD2_k127_6428335_73 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001383 274.0
HFD2_k127_6428335_74 dioxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001241 268.0
HFD2_k127_6428335_75 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007785 271.0
HFD2_k127_6428335_76 proteolysis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000507 254.0
HFD2_k127_6428335_77 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000003995 242.0
HFD2_k127_6428335_78 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000001503 244.0
HFD2_k127_6428335_79 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000001476 231.0
HFD2_k127_6428335_8 hydrolase, family 65, central catalytic K15923 - 3.2.1.51 1.141e-256 814.0
HFD2_k127_6428335_80 Nucleoside recognition K06373,K06374 - - 0.0000000000000000000000000000000000000000000000000000000000000000211 230.0
HFD2_k127_6428335_81 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000003144 229.0
HFD2_k127_6428335_82 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000002312 218.0
HFD2_k127_6428335_83 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000009725 209.0
HFD2_k127_6428335_84 phosphatidylcholine synthase activity K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000002429 214.0
HFD2_k127_6428335_85 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000389 214.0
HFD2_k127_6428335_86 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000105 218.0
HFD2_k127_6428335_87 phosphatidate cytidylyltransferase activity K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000001292 215.0
HFD2_k127_6428335_88 - - - - 0.0000000000000000000000000000000000000000000000000000000001778 214.0
HFD2_k127_6428335_89 InterPro IPR014922 - - - 0.0000000000000000000000000000000000000000000000000000000001981 207.0
HFD2_k127_6428335_9 nuclear chromosome segregation K03529,K19171 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 4.708e-238 784.0
HFD2_k127_6428335_90 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000001358 212.0
HFD2_k127_6428335_91 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000004158 211.0
HFD2_k127_6428335_92 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000006413 207.0
HFD2_k127_6428335_93 GGDEF domain K02478 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000006533 218.0
HFD2_k127_6428335_94 TIGRFAM methionine-R-sulfoxide reductase K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000009264 202.0
HFD2_k127_6428335_95 - - - - 0.000000000000000000000000000000000000000000000000000001224 210.0
HFD2_k127_6428335_96 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000004856 213.0
HFD2_k127_6428335_97 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000001015 203.0
HFD2_k127_6428335_98 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000004833 196.0
HFD2_k127_6428335_99 PAP2 superfamily C-terminal - - - 0.00000000000000000000000000000000000000000000000001794 186.0
HFD2_k127_6548110_0 alpha-galactosidase K07407 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 470.0
HFD2_k127_6548110_1 Hep Hag repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001346 278.0
HFD2_k127_6548110_2 D-aminopeptidase K16203 - - 0.0000000000000000000000000000000000000000000000000000000004612 213.0
HFD2_k127_6548110_3 cellulose binding K01179,K21449 - 3.2.1.4 0.0000000000000000000000000005866 119.0
HFD2_k127_6548110_4 Subtilase family - - - 0.0000117 50.0
HFD2_k127_6567604_0 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 377.0
HFD2_k127_6567604_1 alpha/beta hydrolase fold K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 361.0
HFD2_k127_6567604_10 DinB family - - - 0.0000000000000001465 93.0
HFD2_k127_6567604_11 - - - - 0.00000001525 57.0
HFD2_k127_6567604_2 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002787 241.0
HFD2_k127_6567604_3 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000003942 179.0
HFD2_k127_6567604_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000003812 175.0
HFD2_k127_6567604_5 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000008729 171.0
HFD2_k127_6567604_7 Protein of unknown function (DUF1295) - - - 0.000000000000000000000000000000000000005388 154.0
HFD2_k127_6567604_8 - - - - 0.0000000000000000000000000000003719 141.0
HFD2_k127_6567604_9 zeta toxin - - - 0.0000000000000000000000000000597 121.0
HFD2_k127_6704237_0 Aminotransferase K21572 - - 0.0 1778.0
HFD2_k127_6704237_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1245.0
HFD2_k127_6704237_10 Belongs to the glycosyl hydrolase 43 family K01198,K01209 - 3.2.1.37,3.2.1.55 1.078e-229 750.0
HFD2_k127_6704237_100 Bacteriophage N adsorption protein A C-term - - - 0.0001109 55.0
HFD2_k127_6704237_101 helix_turn_helix multiple antibiotic resistance protein - - - 0.0003671 48.0
HFD2_k127_6704237_11 secondary active sulfate transmembrane transporter activity K06901 - - 1.124e-223 705.0
HFD2_k127_6704237_12 Glycosyl hydrolase family 115 - - - 4.269e-209 689.0
HFD2_k127_6704237_13 Glycosyl hydrolase family 20, catalytic domain K12373 - 3.2.1.52 3.394e-205 664.0
HFD2_k127_6704237_14 Peptidase, M28 - - - 2.712e-196 625.0
HFD2_k127_6704237_15 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 3.407e-194 646.0
HFD2_k127_6704237_16 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 579.0
HFD2_k127_6704237_17 Alpha-L-fucosidase K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 583.0
HFD2_k127_6704237_18 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 561.0
HFD2_k127_6704237_19 L-rhamnose isomerase activity K00848,K01813 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008270,GO:0008740,GO:0009056,GO:0009987,GO:0016043,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0022607,GO:0030145,GO:0030246,GO:0032991,GO:0033296,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0046872,GO:0046914,GO:0048029,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901575 2.7.1.5,5.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009623 545.0
HFD2_k127_6704237_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.34e-307 970.0
HFD2_k127_6704237_20 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 548.0
HFD2_k127_6704237_21 Right handed beta helix region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 533.0
HFD2_k127_6704237_22 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 533.0
HFD2_k127_6704237_23 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 501.0
HFD2_k127_6704237_24 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 499.0
HFD2_k127_6704237_25 PFAM Acetyl xylan esterase K01060 - 3.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006651 492.0
HFD2_k127_6704237_26 Psort location Cytoplasmic, score K00848,K00879 - 2.7.1.5,2.7.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 498.0
HFD2_k127_6704237_27 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 486.0
HFD2_k127_6704237_28 cobalamin-transporting ATPase activity K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000391 477.0
HFD2_k127_6704237_29 Histidine kinase HAMP K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007878 473.0
HFD2_k127_6704237_3 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 1.345e-297 928.0
HFD2_k127_6704237_30 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 449.0
HFD2_k127_6704237_31 Sodium:dicarboxylate symporter family K11102 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 451.0
HFD2_k127_6704237_32 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 441.0
HFD2_k127_6704237_33 unsaturated fatty acid biosynthetic process K04712 - 1.14.18.5,1.14.19.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006507 429.0
HFD2_k127_6704237_34 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 420.0
HFD2_k127_6704237_35 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 423.0
HFD2_k127_6704237_36 M42 glutamyl aminopeptidase K01258 - 3.4.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007248 398.0
HFD2_k127_6704237_37 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 384.0
HFD2_k127_6704237_38 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 382.0
HFD2_k127_6704237_39 enterobactin catabolic process K07214 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 372.0
HFD2_k127_6704237_4 iron-nicotianamine transmembrane transporter activity - - - 4.136e-276 863.0
HFD2_k127_6704237_40 Catalyzes the sodium-dependent transport of glutamate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 357.0
HFD2_k127_6704237_41 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 350.0
HFD2_k127_6704237_42 Fe-S cluster domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 356.0
HFD2_k127_6704237_43 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 343.0
HFD2_k127_6704237_44 Zinc metalloprotease (Elastase) K20274 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 346.0
HFD2_k127_6704237_45 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007642 317.0
HFD2_k127_6704237_46 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 327.0
HFD2_k127_6704237_47 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 310.0
HFD2_k127_6704237_48 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 312.0
HFD2_k127_6704237_49 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002811 292.0
HFD2_k127_6704237_5 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.527e-260 839.0
HFD2_k127_6704237_50 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007871 283.0
HFD2_k127_6704237_51 spore germination K03298 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004449 267.0
HFD2_k127_6704237_52 GDP-mannose mannosyl hydrolase activity K01515,K03574 - 3.6.1.13,3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000006408 259.0
HFD2_k127_6704237_53 Phosphodiester glycosidase K05996 - 3.4.17.18 0.00000000000000000000000000000000000000000000000000000000000000000007561 263.0
HFD2_k127_6704237_54 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001497 252.0
HFD2_k127_6704237_55 polygalacturonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000005696 247.0
HFD2_k127_6704237_56 PFAM 2Fe-2S -binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000005066 226.0
HFD2_k127_6704237_57 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000000000000000000000001606 209.0
HFD2_k127_6704237_58 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000002219 217.0
HFD2_k127_6704237_59 4Fe-4S dicluster domain K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000002247 203.0
HFD2_k127_6704237_6 NADH dehydrogenase K00335,K18331 - 1.12.1.3,1.6.5.3 1.975e-247 777.0
HFD2_k127_6704237_60 PFAM Major Facilitator Superfamily K08151 - - 0.0000000000000000000000000000000000000000000000000000003338 211.0
HFD2_k127_6704237_61 Methyl-viologen-reducing hydrogenase, delta subunit K14127,K14128 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000002966 208.0
HFD2_k127_6704237_62 Lamin Tail Domain K07004 - - 0.000000000000000000000000000000000000000000000000000009311 204.0
HFD2_k127_6704237_63 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000002104 201.0
HFD2_k127_6704237_64 PHP-associated K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000006039 198.0
HFD2_k127_6704237_65 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000002755 189.0
HFD2_k127_6704237_66 Belongs to the 5'-nucleotidase family K01081,K11751 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006213,GO:0006259,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007155,GO:0007159,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009164,GO:0009166,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019362,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0022610,GO:0031974,GO:0031981,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046135,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0051186,GO:0055086,GO:0070013,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0072524,GO:0072527,GO:0072529,GO:0090304,GO:0098609,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000008614 195.0
HFD2_k127_6704237_67 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000009383 178.0
HFD2_k127_6704237_68 SMART ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000001961 184.0
HFD2_k127_6704237_69 Metalloenzyme superfamily - - - 0.00000000000000000000000000000000000000000000006422 185.0
HFD2_k127_6704237_7 C-terminus of AA_permease K03294 - - 5.746e-238 743.0
HFD2_k127_6704237_70 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000003428 168.0
HFD2_k127_6704237_71 PFAM DGPFAETKE family protein - - - 0.00000000000000000000000000000000000000000000928 168.0
HFD2_k127_6704237_72 YCII-related domain - - - 0.00000000000000000000000000000000000000000001499 168.0
HFD2_k127_6704237_73 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000000000000000000000000000001966 182.0
HFD2_k127_6704237_74 TPR repeat - - - 0.0000000000000000000000000000000000000000000249 171.0
HFD2_k127_6704237_75 COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.0000000000000000000000000000000000000000001976 169.0
HFD2_k127_6704237_76 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000002177 159.0
HFD2_k127_6704237_77 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000659 146.0
HFD2_k127_6704237_78 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000009468 154.0
HFD2_k127_6704237_79 Ferredoxin K17992 - 1.12.1.3 0.000000000000000000000000000000001141 133.0
HFD2_k127_6704237_8 Nickel-dependent hydrogenase K14126 - 1.8.98.5 2.914e-237 741.0
HFD2_k127_6704237_80 L-rhamnose mutarotase K03534 - 5.1.3.32 0.000000000000000000000000000000004216 139.0
HFD2_k127_6704237_81 sigma factor antagonist activity K04757,K07315 - 2.7.11.1,3.1.3.3 0.0000000000000000000000000000002689 128.0
HFD2_k127_6704237_82 antisigma factor binding K04749 - - 0.0000000000000000000000000000002704 126.0
HFD2_k127_6704237_83 DRTGG domain - - - 0.00000000000000000000000000006685 119.0
HFD2_k127_6704237_84 cellulose binding - - - 0.0000000000000000000000000001978 136.0
HFD2_k127_6704237_85 DRTGG domain - - - 0.00000000000000000000000001124 117.0
HFD2_k127_6704237_86 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000001278 115.0
HFD2_k127_6704237_87 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000201 124.0
HFD2_k127_6704237_88 protein secretion K15125 - - 0.00000000000000000000003512 118.0
HFD2_k127_6704237_89 Cadherin repeats. - - - 0.00000000000000000003371 108.0
HFD2_k127_6704237_9 Right handed beta helix region - - - 3.977e-231 738.0
HFD2_k127_6704237_90 Hydrogenase maturation protease K03605 - - 0.00000000000000001378 89.0
HFD2_k127_6704237_91 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.0000000000000007707 90.0
HFD2_k127_6704237_92 PFAM Tetratricopeptide repeat - - - 0.000000000001636 79.0
HFD2_k127_6704237_93 Hexapeptide repeat of succinyl-transferase - - - 0.0000000004664 69.0
HFD2_k127_6704237_94 - K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000002478 65.0
HFD2_k127_6704237_95 polysaccharide catabolic process K01179 - 3.2.1.4 0.000000008357 67.0
HFD2_k127_6704237_96 - - - - 0.00000001503 63.0
HFD2_k127_6704237_97 Matrixin - - - 0.00000003739 68.0
HFD2_k127_6788438_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 9.81e-282 880.0
HFD2_k127_6788438_1 mRNA catabolic process K18682 - - 4.292e-214 676.0
HFD2_k127_6788438_10 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000000000000007425 164.0
HFD2_k127_6788438_11 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000001382 153.0
HFD2_k127_6788438_12 protein transport K03210 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000002067 147.0
HFD2_k127_6788438_13 CYTH domain - - - 0.00000000000000000000000000000003354 131.0
HFD2_k127_6788438_14 - - - - 0.00000000000001988 84.0
HFD2_k127_6788438_15 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000007826 74.0
HFD2_k127_6788438_16 - - - - 0.0000001105 55.0
HFD2_k127_6788438_18 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0001034 49.0
HFD2_k127_6788438_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 627.0
HFD2_k127_6788438_3 Queuine tRNA-ribosyltransferase K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007593 474.0
HFD2_k127_6788438_4 phenylalanine-tRNA ligase activity K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 430.0
HFD2_k127_6788438_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 414.0
HFD2_k127_6788438_6 Fumarate reductase flavoprotein C-term K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 349.0
HFD2_k127_6788438_7 Proton-conducting membrane transporter K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 323.0
HFD2_k127_6788438_8 translation initiation factor activity K02520 GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 - 0.0000000000000000000000000000000000000000000000000000000355 203.0
HFD2_k127_6788438_9 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus K03624 - - 0.000000000000000000000000000000000000000000000000004391 186.0
HFD2_k127_7151483_0 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 584.0
HFD2_k127_7151483_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 497.0
HFD2_k127_7151483_10 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002786 272.0
HFD2_k127_7151483_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000006537 237.0
HFD2_k127_7151483_12 - - - - 0.0000000000000000000000000000000000000000000000000000000003943 228.0
HFD2_k127_7151483_13 cellulose binding - - - 0.000000000000000000000000000000000000000000000000003636 201.0
HFD2_k127_7151483_14 nucleotide catabolic process K05996 - 3.4.17.18 0.000000000000000000000000000000000000000000001171 185.0
HFD2_k127_7151483_15 UPF0056 inner membrane protein - - - 0.000000000000000000000000000000000000000001145 163.0
HFD2_k127_7151483_16 FG-GAP repeat protein - - - 0.00000000000000000000005717 110.0
HFD2_k127_7151483_17 translation initiation factor activity K03699 - - 0.0000000000006313 75.0
HFD2_k127_7151483_2 Glycosyl hydrolase family 20, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 517.0
HFD2_k127_7151483_3 Glycosyl hydrolases family 2, TIM barrel domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008459 460.0
HFD2_k127_7151483_4 Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009602 451.0
HFD2_k127_7151483_5 Pectate lyase superfamily protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 384.0
HFD2_k127_7151483_6 purine nucleotide biosynthetic process K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 340.0
HFD2_k127_7151483_7 Glycosyl Hydrolase Family 88 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 342.0
HFD2_k127_7151483_8 symporter activity K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009529 320.0
HFD2_k127_7151483_9 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003126 283.0
HFD2_k127_7184289_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.344e-212 676.0
HFD2_k127_7184289_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 586.0
HFD2_k127_7184289_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K00558,K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 2.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 561.0
HFD2_k127_7184289_3 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 396.0
HFD2_k127_7184289_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 360.0
HFD2_k127_7184289_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 321.0
HFD2_k127_7184289_6 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002749 274.0
HFD2_k127_7184289_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000638 101.0
HFD2_k127_7351133_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1064.0
HFD2_k127_7351133_1 PFAM ABC transporter transmembrane K06147 - - 2.482e-269 842.0
HFD2_k127_7351133_10 drug transmembrane transporter activity K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 443.0
HFD2_k127_7351133_11 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009719 433.0
HFD2_k127_7351133_12 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 418.0
HFD2_k127_7351133_13 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 403.0
HFD2_k127_7351133_14 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 392.0
HFD2_k127_7351133_15 Glycosyl hydrolase family 57 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009209 415.0
HFD2_k127_7351133_16 maltose binding K15770,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 362.0
HFD2_k127_7351133_17 Sugar ABC transporter permease K10109,K15770,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 355.0
HFD2_k127_7351133_18 iron ion homeostasis K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 354.0
HFD2_k127_7351133_19 Binding-protein-dependent transport system inner membrane component K15772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007839 329.0
HFD2_k127_7351133_2 TonB-dependent receptor - - - 5.563e-263 834.0
HFD2_k127_7351133_20 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 351.0
HFD2_k127_7351133_21 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 325.0
HFD2_k127_7351133_22 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 344.0
HFD2_k127_7351133_23 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 296.0
HFD2_k127_7351133_24 Belongs to the 'phage' integrase family K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008341 271.0
HFD2_k127_7351133_25 Glycosyl transferase, family 2 K12984 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005954 256.0
HFD2_k127_7351133_26 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000006088 264.0
HFD2_k127_7351133_27 lipolytic protein G-D-S-L family K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009398 270.0
HFD2_k127_7351133_28 Heptosyltransferase II K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001372 256.0
HFD2_k127_7351133_29 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007739 242.0
HFD2_k127_7351133_3 hydrolase activity, hydrolyzing O-glycosyl compounds K01337 - 3.4.21.50 5.551e-249 804.0
HFD2_k127_7351133_30 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000005491 235.0
HFD2_k127_7351133_31 imidazoleglycerol-phosphate dehydratase K01089,K01693 - 3.1.3.15,4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000181 229.0
HFD2_k127_7351133_32 - - - - 0.0000000000000000000000000000000000000000000000000000000000001005 231.0
HFD2_k127_7351133_33 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000004048 222.0
HFD2_k127_7351133_34 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000329 219.0
HFD2_k127_7351133_35 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000005941 205.0
HFD2_k127_7351133_36 COGs COG1392 Phosphate transport regulator (distant homolog of PhoU) K07220 - - 0.00000000000000000000000000000000000000000000000000000008431 203.0
HFD2_k127_7351133_37 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000009119 204.0
HFD2_k127_7351133_38 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000001153 201.0
HFD2_k127_7351133_39 Kdo2-lipid A biosynthetic process K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000002774 202.0
HFD2_k127_7351133_4 (ABC) transporter K02021,K06147,K06148,K11085 - - 7.205e-223 711.0
HFD2_k127_7351133_40 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000001556 188.0
HFD2_k127_7351133_41 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000006114 164.0
HFD2_k127_7351133_42 antisigma factor binding K04749,K06378 - - 0.0000000000000000000000000000000000000001007 153.0
HFD2_k127_7351133_43 sigma factor antagonist activity K04757 - 2.7.11.1 0.00000000000000000000000000000000003216 139.0
HFD2_k127_7351133_44 protein trimerization - - - 0.0000000000000000000000000000002019 135.0
HFD2_k127_7351133_45 Cold shock K03704 - - 0.00000000000000000000000007925 108.0
HFD2_k127_7351133_46 chain release factor K15034 - - 0.0000000000000000000000006841 110.0
HFD2_k127_7351133_47 HNH nucleases - - - 0.0000000000000000002228 90.0
HFD2_k127_7351133_48 Protein of unknown function (DUF4013) - - - 0.00000000000000000208 95.0
HFD2_k127_7351133_49 Domain of unknown function (DUF1844) - - - 0.000000000000000002399 94.0
HFD2_k127_7351133_5 Protein of unknown function, DUF255 K06888 - - 5.258e-215 692.0
HFD2_k127_7351133_50 Tetratricopeptide repeat - - - 0.000000000000000003616 95.0
HFD2_k127_7351133_51 Cytochrome c - - - 0.000000000000001575 88.0
HFD2_k127_7351133_52 - - - - 0.0000000000000025 87.0
HFD2_k127_7351133_53 hemerythrin HHE cation binding domain - - - 0.000000000000004629 86.0
HFD2_k127_7351133_54 O-antigen polymerase - - - 0.000000000005208 78.0
HFD2_k127_7351133_55 Transcriptional regulatory protein, C terminal - - - 0.00000000001315 75.0
HFD2_k127_7351133_56 1,4-alpha-glucan branching enzyme activity K00700 - 2.4.1.18 0.00000004028 67.0
HFD2_k127_7351133_57 - - - - 0.00006125 48.0
HFD2_k127_7351133_58 - - - - 0.00006785 48.0
HFD2_k127_7351133_59 Starch binding domain-containing protein K00516 - 1.14.99.55 0.00009033 56.0
HFD2_k127_7351133_6 oligopeptide transport K03305 - - 7.439e-211 666.0
HFD2_k127_7351133_60 Tetratricopeptide TPR_2 - - - 0.0001436 51.0
HFD2_k127_7351133_7 PFAM alpha amylase, catalytic region - - - 3.923e-208 665.0
HFD2_k127_7351133_8 Major facilitator superfamily K16211 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 577.0
HFD2_k127_7351133_9 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007826 466.0
HFD2_k127_7434796_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 492.0
HFD2_k127_7434796_1 N-terminus of Esterase_SGNH_hydro-type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007975 413.0
HFD2_k127_7434796_2 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 334.0
HFD2_k127_7434796_3 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002197 259.0
HFD2_k127_7434796_4 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000003289 166.0
HFD2_k127_7434796_5 lactoylglutathione lyase activity - - - 0.00000000000000000000000000116 116.0
HFD2_k127_752780_0 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 347.0
HFD2_k127_752780_1 membrane-bound metal-dependent K07038 - - 0.0000000000000000000000000000000000002043 160.0
HFD2_k127_752780_2 Propionate catabolism activator - - - 0.000000000000000000003329 104.0
HFD2_k127_752780_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000004283 85.0
HFD2_k127_752780_4 Replication initiation and membrane attachment - - - 0.000000005094 67.0
HFD2_k127_752780_5 Phage integrase family - - - 0.0000003811 61.0
HFD2_k127_752780_6 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00001358 57.0
HFD2_k127_752780_7 PFAM glycoside hydrolase, family 13 domain protein - - - 0.0007833 48.0
HFD2_k127_7909003_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 2.136e-299 936.0
HFD2_k127_7909003_1 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 1.503e-254 812.0
HFD2_k127_7909003_10 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005065 436.0
HFD2_k127_7909003_11 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 397.0
HFD2_k127_7909003_12 pectate lyase K01728 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 368.0
HFD2_k127_7909003_13 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 308.0
HFD2_k127_7909003_14 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001356 280.0
HFD2_k127_7909003_15 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002667 256.0
HFD2_k127_7909003_16 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000002953 231.0
HFD2_k127_7909003_17 - - - - 0.000000000000000000000000000000000000000000000000001888 187.0
HFD2_k127_7909003_18 transcription factor binding - - - 0.0000000000000000000000000000000000002951 143.0
HFD2_k127_7909003_19 DinB family - - - 0.0000000000000000000000000000000000006447 145.0
HFD2_k127_7909003_2 FAD linked oxidase domain protein - - - 1.211e-232 729.0
HFD2_k127_7909003_20 NHL repeat containing protein - - - 0.0000000000000000000000000000005813 134.0
HFD2_k127_7909003_22 hydrolase activity, hydrolyzing O-glycosyl compounds K01337 - 3.4.21.50 0.00000000000000000000004594 115.0
HFD2_k127_7909003_23 hydrolase activity, hydrolyzing O-glycosyl compounds K01337 - 3.4.21.50 0.00000000000000000000006681 109.0
HFD2_k127_7909003_24 PEGA domain - - - 0.000000000000000000009749 98.0
HFD2_k127_7909003_25 - - - - 0.00000004913 61.0
HFD2_k127_7909003_27 Outer membrane protein beta-barrel domain - - - 0.00001954 56.0
HFD2_k127_7909003_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 4.29e-232 734.0
HFD2_k127_7909003_4 FAD linked oxidase domain protein - - - 3.511e-223 702.0
HFD2_k127_7909003_5 enterotoxin - - - 1.789e-199 654.0
HFD2_k127_7909003_6 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 576.0
HFD2_k127_7909003_7 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 560.0
HFD2_k127_7909003_8 Cache domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 490.0
HFD2_k127_7909003_9 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 496.0
HFD2_k127_7909467_0 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 1.066e-227 713.0
HFD2_k127_7909467_1 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 605.0
HFD2_k127_7909467_10 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 469.0
HFD2_k127_7909467_11 X-Pro dipeptidyl-peptidase (S15 family) K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006137 473.0
HFD2_k127_7909467_12 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 409.0
HFD2_k127_7909467_13 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175,K00187 - 1.2.7.11,1.2.7.3,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 399.0
HFD2_k127_7909467_14 Tat pathway signal sequence domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009218 371.0
HFD2_k127_7909467_15 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 353.0
HFD2_k127_7909467_16 COG1538 Outer membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 344.0
HFD2_k127_7909467_17 epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 294.0
HFD2_k127_7909467_18 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001889 296.0
HFD2_k127_7909467_19 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00177,K00187 - 1.2.7.3,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000003347 244.0
HFD2_k127_7909467_2 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 578.0
HFD2_k127_7909467_20 peptide methionine sulfoxide reductase K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000215 228.0
HFD2_k127_7909467_21 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000003493 224.0
HFD2_k127_7909467_22 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000001525 197.0
HFD2_k127_7909467_23 Protein conserved in bacteria K07192 - - 0.00000000000000000000000000000000000000000000000006331 200.0
HFD2_k127_7909467_24 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.0000000000000000000000000000000000000000000000001304 190.0
HFD2_k127_7909467_25 Haem-binding domain - - - 0.000000000000000000000000000000000003024 143.0
HFD2_k127_7909467_26 Pyridoxal-phosphate dependent enzyme - - - 0.00000000000000000000000000000004028 127.0
HFD2_k127_7909467_27 response to oxidative stress - - - 0.000000000000000000000000000008173 126.0
HFD2_k127_7909467_28 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.00000000000000000000000000161 124.0
HFD2_k127_7909467_29 PFAM blue (type 1) copper domain protein - - - 0.000000000000000004304 91.0
HFD2_k127_7909467_3 coproporphyrinogen oxidase activity K02495 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 565.0
HFD2_k127_7909467_30 - - - - 0.000000000000002827 79.0
HFD2_k127_7909467_32 Pectinesterase - - - 0.00000000000001876 87.0
HFD2_k127_7909467_33 PFAM Planctomycete cytochrome C - - - 0.0000000000008904 74.0
HFD2_k127_7909467_34 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.00000000002074 72.0
HFD2_k127_7909467_35 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.00000000002894 77.0
HFD2_k127_7909467_37 methyltransferase activity - - - 0.0000000004712 67.0
HFD2_k127_7909467_38 Copper resistance protein D - - - 0.000001954 56.0
HFD2_k127_7909467_4 Alpha-glucosidase K01187 - 3.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 551.0
HFD2_k127_7909467_5 cystathionine gamma-synthase activity K01758,K01760,K01761 - 4.4.1.1,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 507.0
HFD2_k127_7909467_6 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000829 510.0
HFD2_k127_7909467_7 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 480.0
HFD2_k127_7909467_8 Cytochrome C-type biogenesis protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 493.0
HFD2_k127_7909467_9 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 474.0
HFD2_k127_7927799_0 helix_turn_helix, Lux Regulon K11618 - - 0.0000000000000000000000000000000000000000000000000000000002106 218.0
HFD2_k127_7927799_1 Histidine kinase - - - 0.00000000000000000000000000000000000000001932 175.0
HFD2_k127_7927799_2 nuclear chromosome segregation K12472 - - 0.000000000000000000000000189 117.0
HFD2_k127_7927799_3 - - - - 0.000003143 56.0
HFD2_k127_8044290_0 Polysaccharide biosynthesis C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009941 322.0
HFD2_k127_8044290_1 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002409 265.0
HFD2_k127_8044290_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000001532 222.0
HFD2_k127_8044290_3 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000004078 225.0
HFD2_k127_8058850_0 PFAM glycoside hydrolase, family 29 K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005643 610.0
HFD2_k127_8058850_1 Pectate lyase superfamily protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007709 480.0
HFD2_k127_8058850_2 Domain of unknown function (DUF4861) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 394.0
HFD2_k127_8137993_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009415 484.0
HFD2_k127_8137993_1 Glycosyl transferase, family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 450.0
HFD2_k127_8137993_10 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000004451 145.0
HFD2_k127_8137993_11 Pkd domain containing protein - - - 0.0000000000000000000002778 114.0
HFD2_k127_8137993_12 cellulose binding - - - 0.000000000000000000001458 111.0
HFD2_k127_8137993_13 cellulose binding - - - 0.00000000000000000001734 107.0
HFD2_k127_8137993_14 Histidine kinase - - - 0.0000000000000002886 87.0
HFD2_k127_8137993_15 SusE outer membrane protein K01216,K12287 - 3.2.1.73 0.000000000000007848 87.0
HFD2_k127_8137993_2 glucose sorbosone K00117 - 1.1.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 434.0
HFD2_k127_8137993_3 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 304.0
HFD2_k127_8137993_4 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000002891 270.0
HFD2_k127_8137993_5 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001745 256.0
HFD2_k127_8137993_6 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002248 274.0
HFD2_k127_8137993_7 Glyco_18 - - - 0.00000000000000000000000000000000000000000000000001548 206.0
HFD2_k127_8137993_8 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000008572 187.0
HFD2_k127_8137993_9 chitin binding K01183 - 3.2.1.14 0.00000000000000000000000000000000000000000001221 185.0
HFD2_k127_843700_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 302.0
HFD2_k127_8684268_0 PFAM Uncharacterised BCR, COG1649 - - - 0.0000000000000000000004323 113.0
HFD2_k127_8684268_1 Rhomboid family - - - 0.00000000000000000008173 106.0
HFD2_k127_8684268_2 PFAM Alcohol dehydrogenase, zinc-binding K00344 - 1.6.5.5 0.000000000000000496 78.0
HFD2_k127_885058_0 PFAM TonB-dependent Receptor Plug Domain - - - 0.0 1283.0
HFD2_k127_885058_1 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 6.183e-299 927.0
HFD2_k127_885058_10 Parallel beta-helix repeat K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 308.0
HFD2_k127_885058_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 301.0
HFD2_k127_885058_12 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000001738 223.0
HFD2_k127_885058_13 lipoprotein involved in nitrous oxide reduction - - - 0.00000000000000000000000000000000000000000000000000000000001257 218.0
HFD2_k127_885058_14 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000001883 227.0
HFD2_k127_885058_15 ABC transporter K01990,K19340 - - 0.00000000000000000000000000000000000000000000000000000000007766 216.0
HFD2_k127_885058_16 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000000129 193.0
HFD2_k127_885058_17 ABC-2 family transporter protein K19341 - - 0.0000000000000000000000000000000000000000000000000002107 196.0
HFD2_k127_885058_18 - - - - 0.0000000000000000000000000000000000000000000001448 184.0
HFD2_k127_885058_19 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000000000000000000001211 166.0
HFD2_k127_885058_2 fibronectin type III domain protein - - - 2.304e-268 844.0
HFD2_k127_885058_20 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.0000000000000000000000000000000000000000006527 173.0
HFD2_k127_885058_21 cellulose binding - - - 0.00000000000000000000000000000000000000009772 169.0
HFD2_k127_885058_22 - - - - 0.0000000000000000000000000000000000001361 153.0
HFD2_k127_885058_23 Belongs to the peptidase S8 family - - - 0.00000000000000000001698 106.0
HFD2_k127_885058_24 NosL K19342 - - 0.00000000000000001485 89.0
HFD2_k127_885058_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 7.725e-240 756.0
HFD2_k127_885058_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 545.0
HFD2_k127_885058_5 Alpha-L-rhamnosidase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 512.0
HFD2_k127_885058_6 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 468.0
HFD2_k127_885058_7 Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 368.0
HFD2_k127_885058_8 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 344.0
HFD2_k127_885058_9 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007976 328.0
HFD2_k127_920171_0 DNA-directed DNA polymerase activity K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1192.0
HFD2_k127_920171_1 TonB-dependent receptor - - - 8.674e-279 889.0
HFD2_k127_920171_10 Bacterial protein of unknown function (DUF853) - - - 2.303e-208 658.0
HFD2_k127_920171_100 membrane - - - 0.000000000000000000000000000000000000000001239 163.0
HFD2_k127_920171_101 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.000000000000000000000000000000000000000004939 164.0
HFD2_k127_920171_102 Thioredoxin K03671 - - 0.00000000000000000000000000000000000000006243 156.0
HFD2_k127_920171_103 - - - - 0.000000000000000000000000000000000000001409 155.0
HFD2_k127_920171_104 - - - - 0.000000000000000000000000000000000000009025 151.0
HFD2_k127_920171_105 Psort location Cytoplasmic, score 8.96 - - - 0.00000000000000000000000000000000005248 136.0
HFD2_k127_920171_106 Outer membrane protein protective antigen OMA87 - - - 0.0000000000000000000000000000000001513 153.0
HFD2_k127_920171_107 Pfam:DUF59 K02612 - - 0.000000000000000000000000000000001355 139.0
HFD2_k127_920171_108 - - - - 0.00000000000000000000000000000002351 129.0
HFD2_k127_920171_109 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.000000000000000000000000000001468 137.0
HFD2_k127_920171_11 glucuronate isomerase activity K01812 GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019585,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0042839,GO:0042840,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0071704,GO:0072329,GO:1901575 5.3.1.12 9.464e-196 623.0
HFD2_k127_920171_110 transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000004913 124.0
HFD2_k127_920171_111 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000001679 124.0
HFD2_k127_920171_112 COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog K03088 - - 0.00000000000000000000000000003847 123.0
HFD2_k127_920171_113 intermediate-associated protein 30 - - - 0.0000000000000000000000000001985 123.0
HFD2_k127_920171_114 Domain of unknown function (DUF4974) - - - 0.0000000000000000000000000004964 126.0
HFD2_k127_920171_115 Signal peptidase (SPase) II K03101 - 3.4.23.36 0.0000000000000000000000000006322 119.0
HFD2_k127_920171_116 - - - - 0.00000000000000000000000001506 126.0
HFD2_k127_920171_118 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000001405 114.0
HFD2_k127_920171_119 Transcriptional regulator - - - 0.0000000000000000000000002632 117.0
HFD2_k127_920171_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007306 629.0
HFD2_k127_920171_121 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA - - - 0.0000000000000000000000101 108.0
HFD2_k127_920171_122 Domain of unknown function (DUF4974) - - - 0.00000000000000000009304 100.0
HFD2_k127_920171_123 Uncharacterized protein conserved in bacteria (DUF2064) K09931,K20742 - 3.4.14.13 0.00000000000000001382 94.0
HFD2_k127_920171_125 Transglutaminase-like superfamily - - - 0.0000000000000001559 93.0
HFD2_k127_920171_126 regulation of translation K03733,K05808,K05809 - - 0.0000000000000003216 82.0
HFD2_k127_920171_127 photosystem II stabilization - - - 0.0000000000000003564 89.0
HFD2_k127_920171_128 Belongs to the Smg family K03747 - - 0.0000000000000007282 83.0
HFD2_k127_920171_129 - - - - 0.0000000000000009176 82.0
HFD2_k127_920171_13 PFAM Glycosyl hydrolase family 1 K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 605.0
HFD2_k127_920171_130 PFAM Radical SAM - - - 0.00000000000001455 86.0
HFD2_k127_920171_131 Protein of unknown function DUF116 - - - 0.0000000000002882 80.0
HFD2_k127_920171_133 Belongs to the N(4) N(6)-methyltransferase family - - - 0.000000000006424 79.0
HFD2_k127_920171_134 Iron-containing redox enzyme K06137 - 1.3.3.11 0.00000000002251 72.0
HFD2_k127_920171_135 Caspase domain - - - 0.00000000002656 76.0
HFD2_k127_920171_136 - - - - 0.00000000003217 71.0
HFD2_k127_920171_137 AraC-like ligand binding domain - - - 0.0000000001676 74.0
HFD2_k127_920171_138 - - - - 0.000000001739 68.0
HFD2_k127_920171_139 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000005398 60.0
HFD2_k127_920171_14 Belongs to the glycosyl hydrolase 43 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 607.0
HFD2_k127_920171_140 Psort location OuterMembrane, score - - - 0.00000001137 68.0
HFD2_k127_920171_142 Outer membrane protein beta-barrel domain K07275 - - 0.00002869 54.0
HFD2_k127_920171_143 Iron-sulphur cluster assembly - - - 0.0003354 48.0
HFD2_k127_920171_15 PfkB domain protein K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 599.0
HFD2_k127_920171_16 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 593.0
HFD2_k127_920171_17 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 587.0
HFD2_k127_920171_18 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 578.0
HFD2_k127_920171_19 acetate kinase activity K00925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 575.0
HFD2_k127_920171_2 methionyl-tRNA aminoacylation K01874,K01890,K06878 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20 1.388e-275 863.0
HFD2_k127_920171_20 PFAM Major Facilitator Superfamily K08191 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 555.0
HFD2_k127_920171_21 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 552.0
HFD2_k127_920171_22 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 543.0
HFD2_k127_920171_23 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009888 540.0
HFD2_k127_920171_24 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007299 531.0
HFD2_k127_920171_25 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 520.0
HFD2_k127_920171_26 Aminotransferase K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 510.0
HFD2_k127_920171_27 tagaturonate epimerase K21619 - 5.1.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 507.0
HFD2_k127_920171_28 transferase activity, transferring glycosyl groups K00754 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 503.0
HFD2_k127_920171_29 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 518.0
HFD2_k127_920171_3 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 4.896e-269 849.0
HFD2_k127_920171_30 pectinesterase activity K01218,K01224 - 3.2.1.78,3.2.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 507.0
HFD2_k127_920171_31 COG COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007711 503.0
HFD2_k127_920171_32 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 501.0
HFD2_k127_920171_33 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005385 492.0
HFD2_k127_920171_34 Peptidase, M16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 482.0
HFD2_k127_920171_35 Alanine-glyoxylate amino-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007122 484.0
HFD2_k127_920171_36 Peptidase m28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 474.0
HFD2_k127_920171_37 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 464.0
HFD2_k127_920171_38 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 445.0
HFD2_k127_920171_39 Belongs to the glycosyl hydrolase 28 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 451.0
HFD2_k127_920171_4 FeS assembly protein SufB K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 4.524e-264 820.0
HFD2_k127_920171_40 Belongs to the glycosyl hydrolase 28 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 452.0
HFD2_k127_920171_41 Methanol-cobalamin methyltransferase B subunit K04480 - 2.1.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 444.0
HFD2_k127_920171_42 radical SAM domain protein K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 448.0
HFD2_k127_920171_43 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 433.0
HFD2_k127_920171_44 BNR repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 431.0
HFD2_k127_920171_45 Xylose isomerase-like TIM barrel K18910 - 5.1.3.30,5.1.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 412.0
HFD2_k127_920171_46 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 413.0
HFD2_k127_920171_47 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 409.0
HFD2_k127_920171_48 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 400.0
HFD2_k127_920171_49 ATPase activity K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 396.0
HFD2_k127_920171_5 Phosphoesterase family - - - 4.828e-252 806.0
HFD2_k127_920171_50 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 406.0
HFD2_k127_920171_51 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 398.0
HFD2_k127_920171_52 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007161 421.0
HFD2_k127_920171_53 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 385.0
HFD2_k127_920171_54 Pyridine nucleotide-disulphide oxidoreductase K00384,K21567 - 1.18.1.2,1.19.1.1,1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 394.0
HFD2_k127_920171_55 Putative glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 372.0
HFD2_k127_920171_56 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 370.0
HFD2_k127_920171_57 Pectinesterase K01051 - 3.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 368.0
HFD2_k127_920171_58 FeS assembly protein SufD K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 369.0
HFD2_k127_920171_59 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006334 353.0
HFD2_k127_920171_6 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 3.413e-245 781.0
HFD2_k127_920171_60 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 355.0
HFD2_k127_920171_61 Domain of unknown function (DUF4857) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 334.0
HFD2_k127_920171_62 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 334.0
HFD2_k127_920171_63 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 317.0
HFD2_k127_920171_64 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 307.0
HFD2_k127_920171_65 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 298.0
HFD2_k127_920171_66 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 316.0
HFD2_k127_920171_67 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 303.0
HFD2_k127_920171_68 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 289.0
HFD2_k127_920171_69 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003791 287.0
HFD2_k127_920171_7 prolyl-tRNA aminoacylation K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 2.107e-232 732.0
HFD2_k127_920171_70 cAMP biosynthetic process K18672 GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001487 284.0
HFD2_k127_920171_71 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000222 287.0
HFD2_k127_920171_72 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005788 278.0
HFD2_k127_920171_73 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002057 282.0
HFD2_k127_920171_74 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005965 302.0
HFD2_k127_920171_75 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008454 279.0
HFD2_k127_920171_76 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006819 258.0
HFD2_k127_920171_77 Phage integrase, N-terminal SAM-like domain K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000002585 250.0
HFD2_k127_920171_78 PA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000214 252.0
HFD2_k127_920171_79 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000001647 242.0
HFD2_k127_920171_8 glutamine synthetase K01915 - 6.3.1.2 8.831e-229 718.0
HFD2_k127_920171_80 ferredoxin-NADP+ reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000002217 230.0
HFD2_k127_920171_81 PFAM TonB-dependent Receptor Plug - - - 0.0000000000000000000000000000000000000000000000000000000000000008673 246.0
HFD2_k127_920171_82 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000003585 224.0
HFD2_k127_920171_83 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000004713 218.0
HFD2_k127_920171_84 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000003673 217.0
HFD2_k127_920171_85 heme binding K21471 - - 0.000000000000000000000000000000000000000000000000000000009965 212.0
HFD2_k127_920171_86 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004784,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010269,GO:0010447,GO:0016020,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0020012,GO:0030145,GO:0030682,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052059,GO:0052173,GO:0052200,GO:0052385,GO:0052550,GO:0052564,GO:0052567,GO:0052572,GO:0055114,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071291,GO:0071450,GO:0071451,GO:0071944,GO:0072593,GO:0075136,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.00000000000000000000000000000000000000000000000000000002706 205.0
HFD2_k127_920171_87 Protein of unknown function (DUF4876) - - - 0.00000000000000000000000000000000000000000000000000000009695 209.0
HFD2_k127_920171_88 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000001492 197.0
HFD2_k127_920171_89 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.000000000000000000000000000000000000000000000006438 180.0
HFD2_k127_920171_9 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 4.064e-210 667.0
HFD2_k127_920171_90 TIGRFAM SUF system FeS K04488 - - 0.00000000000000000000000000000000000000000000001805 187.0
HFD2_k127_920171_91 Pfam:TPM K08988 - - 0.0000000000000000000000000000000000000000000000539 177.0
HFD2_k127_920171_92 Domain of unknown function (DUF1949) - - - 0.00000000000000000000000000000000000000000000006035 179.0
HFD2_k127_920171_93 protein maturation K13628 - - 0.0000000000000000000000000000000000000000000001339 171.0
HFD2_k127_920171_94 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000001133 170.0
HFD2_k127_920171_95 Domain of unknown function (DUF4835) - - - 0.000000000000000000000000000000000000000000001703 177.0
HFD2_k127_920171_96 cellulose binding - - - 0.00000000000000000000000000000000000000000006068 183.0
HFD2_k127_920171_97 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000001409 169.0
HFD2_k127_920171_98 pfam abc K01990 - - 0.0000000000000000000000000000000000000000001845 178.0
HFD2_k127_920171_99 Pilus assembly protein PilX K02673 - - 0.0000000000000000000000000000000000000000002459 175.0
HFD2_k127_926279_0 aconitate hydratase activity K01681 - 4.2.1.3 0.0 1091.0
HFD2_k127_926279_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 6.066e-305 959.0
HFD2_k127_926279_10 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 359.0
HFD2_k127_926279_11 Glycosyl transferase family group 2 K11740 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 356.0
HFD2_k127_926279_12 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 354.0
HFD2_k127_926279_13 DNA mediated transformation K02342,K03168,K03703,K04096 - 2.7.7.7,5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 342.0
HFD2_k127_926279_14 Bacterial sugar transferase K03606 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 333.0
HFD2_k127_926279_15 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000522 347.0
HFD2_k127_926279_16 PFAM glycoside hydrolase, family 3 domain protein K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 320.0
HFD2_k127_926279_17 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007827 287.0
HFD2_k127_926279_18 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004962 275.0
HFD2_k127_926279_19 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006921 266.0
HFD2_k127_926279_2 Peptidase S46 - - - 5.832e-250 792.0
HFD2_k127_926279_20 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006662 263.0
HFD2_k127_926279_21 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001508 254.0
HFD2_k127_926279_22 Belongs to the 5'-nucleotidase family K01081,K11751,K17224 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000005242 262.0
HFD2_k127_926279_23 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000001586 250.0
HFD2_k127_926279_24 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000002631 236.0
HFD2_k127_926279_25 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000001324 245.0
HFD2_k127_926279_26 PFAM Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002639 236.0
HFD2_k127_926279_27 long-chain fatty acid transporting porin activity K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000002832 241.0
HFD2_k127_926279_28 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000008965 240.0
HFD2_k127_926279_29 bacteriocin transport K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000003265 230.0
HFD2_k127_926279_3 isocitrate dehydrogenase activity K00031 GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 5.747e-206 649.0
HFD2_k127_926279_30 D-glycero-D-manno-heptose 7-phosphate metabolic process K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000001323 227.0
HFD2_k127_926279_31 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000006487 204.0
HFD2_k127_926279_33 Base excision DNA repair protein, HhH-GPD family K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000103 201.0
HFD2_k127_926279_34 Belongs to the UPF0403 family - - - 0.0000000000000000000000000000000000000000000004522 171.0
HFD2_k127_926279_35 Protein of unknown function (DUF3109) - - - 0.000000000000000000000000000000000000000000002208 171.0
HFD2_k127_926279_36 response regulator, receiver - - - 0.00000000000000000000000000000000000000000001048 184.0
HFD2_k127_926279_38 Histidine kinase K01768,K12132 - 2.7.11.1,4.6.1.1 0.000000000000000000000000000000000002637 143.0
HFD2_k127_926279_39 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000002559 141.0
HFD2_k127_926279_4 Major Facilitator Superfamily K02445 - - 2.524e-199 631.0
HFD2_k127_926279_40 cellulose binding - - - 0.000000000000000000000002907 121.0
HFD2_k127_926279_41 response regulator K07658 - - 0.000000000000000000000003352 106.0
HFD2_k127_926279_42 PFAM ATP-dependent Clp protease adaptor protein ClpS - - - 0.00000000000000000000002404 104.0
HFD2_k127_926279_43 Protein conserved in bacteria - - - 0.000000000000000000000103 113.0
HFD2_k127_926279_44 - - - - 0.0000000000000000000002722 103.0
HFD2_k127_926279_45 DinB superfamily - - - 0.00000000000000000002846 106.0
HFD2_k127_926279_47 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000001107 95.0
HFD2_k127_926279_48 - - - - 0.00000000000000000746 95.0
HFD2_k127_926279_49 - - - - 0.00000000000000004616 83.0
HFD2_k127_926279_5 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 601.0
HFD2_k127_926279_52 - - - - 0.0000000000393 74.0
HFD2_k127_926279_54 Sporulation related domain - - - 0.00002646 56.0
HFD2_k127_926279_55 Domain of unknown function (DUF4412) - - - 0.0001041 53.0
HFD2_k127_926279_56 energy transducer activity K03832,K08086 - - 0.0002764 51.0
HFD2_k127_926279_57 regulation of translation K03530 - - 0.0006253 47.0
HFD2_k127_926279_58 Sigma-70, region 4 K03088 - - 0.0006326 49.0
HFD2_k127_926279_6 Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 475.0
HFD2_k127_926279_7 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 464.0
HFD2_k127_926279_8 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 443.0
HFD2_k127_926279_9 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007741 443.0