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Overview

ID MAG01646
Name HFD2_bin.34
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Anaerolineae
Order Aggregatilineales
Family UBA2796
Genus JAJPHV01
Species
Assembly information
Completeness (%) 90.77
Contamination (%) 5.81
GC content (%) 59.0
N50 (bp) 7,034
Genome size (bp) 8,027,813

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes6678

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_1014515_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 9.443e-204 645.0
HFD2_k127_1014515_1 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001346 268.0
HFD2_k127_1018213_0 transposase activity - - - 0.000000000000000000000000000000000000000000000000000000000000004339 233.0
HFD2_k127_1018308_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000622 584.0
HFD2_k127_1023066_0 Glucose dehydrogenase C-terminus K00008,K00060 - 1.1.1.103,1.1.1.14 1.949e-201 630.0
HFD2_k127_1023066_1 PFAM Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002954 278.0
HFD2_k127_1023066_2 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003989 271.0
HFD2_k127_1023066_3 TIGRFAM LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000006841 231.0
HFD2_k127_1023066_4 Cobalamin B12-binding K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000005286 201.0
HFD2_k127_1023066_5 Mazg nucleotide pyrophosphohydrolase - - - 0.000000000000000000000000000002826 122.0
HFD2_k127_1023066_6 TIGRFAM LAO AO transport system ATPase K07588 - - 0.000000000000000000000007084 107.0
HFD2_k127_1023066_7 Protein of unknown function (DUF402) K07586 - - 0.000000000000000000006305 98.0
HFD2_k127_1023066_8 LysM domain K12204 - - 0.00000223 53.0
HFD2_k127_1028012_0 Peptidase M3A and M3B thimet oligopeptidase F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 456.0
HFD2_k127_1028012_1 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 357.0
HFD2_k127_1028012_2 Amidohydrolase family - - - 0.000002453 53.0
HFD2_k127_1030103_0 Alpha amylase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000008835 224.0
HFD2_k127_1030103_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000002843 201.0
HFD2_k127_1030103_2 - - - - 0.000000000000000001461 95.0
HFD2_k127_1031681_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 286.0
HFD2_k127_1031681_1 regulation of circadian rhythm K08482 - - 0.00000000000000000000000000000000000000000000000000002004 198.0
HFD2_k127_104136_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 451.0
HFD2_k127_104136_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 381.0
HFD2_k127_104136_2 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 321.0
HFD2_k127_104136_3 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001307 264.0
HFD2_k127_104136_4 SMART PAS domain containing protein - - - 0.000000000000000000000000000003886 125.0
HFD2_k127_104136_5 Protein of unknown function (DUF2905) - - - 0.00000003367 59.0
HFD2_k127_1042741_0 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008745 355.0
HFD2_k127_1042741_1 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 317.0
HFD2_k127_1042741_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002725 272.0
HFD2_k127_1042741_3 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000001817 89.0
HFD2_k127_1042741_4 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000002055 63.0
HFD2_k127_1042741_5 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00003881 55.0
HFD2_k127_1043682_0 PFAM binding-protein-dependent transport systems inner membrane component K15772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 395.0
HFD2_k127_1043682_1 PFAM binding-protein-dependent transport systems inner membrane component K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 391.0
HFD2_k127_1048238_0 6-phosphogluconolactonase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 437.0
HFD2_k127_1048238_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000003993 188.0
HFD2_k127_1048238_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000003931 124.0
HFD2_k127_1048238_3 - - - - 0.0000000000000001426 81.0
HFD2_k127_1048238_4 Plasmid stabilization system - - - 0.0000000000000001426 81.0
HFD2_k127_1048238_5 domain protein K01179,K12567,K20276,K21449 - 2.7.11.1,3.2.1.4 0.000000000000001952 92.0
HFD2_k127_1048238_7 - - - - 0.0000000004093 63.0
HFD2_k127_1048238_8 transcription factor binding K15836 - - 0.000003899 48.0
HFD2_k127_1057700_0 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 5.877e-294 917.0
HFD2_k127_1090872_0 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000038 254.0
HFD2_k127_1090872_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000004623 108.0
HFD2_k127_1090872_2 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000001515 94.0
HFD2_k127_1090872_3 AAA domain - - - 0.0000000004321 74.0
HFD2_k127_1097928_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1382.0
HFD2_k127_1097928_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 516.0
HFD2_k127_1097928_10 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000003389 68.0
HFD2_k127_1097928_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000273 67.0
HFD2_k127_1097928_12 Membrane - - - 0.0003287 53.0
HFD2_k127_1097928_13 Alpha beta hydrolase - - - 0.0008873 51.0
HFD2_k127_1097928_2 PFAM Glycosyl transferase family 2 K10012 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 316.0
HFD2_k127_1097928_3 Binding-protein-dependent transport system inner membrane component K02018,K02046 - - 0.000000000000000000000000000000000000000000000000000000000000003883 226.0
HFD2_k127_1097928_4 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000001518 167.0
HFD2_k127_1097928_5 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.000000000000000000000000000000000000000003055 162.0
HFD2_k127_1097928_6 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000002287 149.0
HFD2_k127_1097928_7 Cytochrome c K17222 - - 0.0000000000000000000000000003641 128.0
HFD2_k127_1097928_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000005307 79.0
HFD2_k127_1097928_9 Trehalase - - - 0.00000000005021 74.0
HFD2_k127_1100066_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 2.623e-204 660.0
HFD2_k127_1100066_1 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000001048 220.0
HFD2_k127_1100066_2 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 0.00000000001568 64.0
HFD2_k127_1101210_0 Anion-transporting ATPase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001222 264.0
HFD2_k127_1101210_1 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000001843 211.0
HFD2_k127_1101210_2 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.00000000000002083 78.0
HFD2_k127_1104111_0 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 447.0
HFD2_k127_1104111_1 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 415.0
HFD2_k127_1104111_2 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 377.0
HFD2_k127_1104111_3 Glycosyltransferase WbsX - - - 0.00007283 48.0
HFD2_k127_1109894_0 Transposase (IS116 IS110 IS902 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 356.0
HFD2_k127_1109894_1 Transposase - - - 0.0000000000000231 80.0
HFD2_k127_1109894_2 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791,K13019 - 5.1.3.14,5.1.3.23 0.00000000002939 65.0
HFD2_k127_1109894_3 PFAM Transposase - - - 0.0000000001008 68.0
HFD2_k127_1109894_4 - - - - 0.00000003423 62.0
HFD2_k127_1113753_0 Response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000005645 106.0
HFD2_k127_1113753_1 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K05825 - - 0.0000000002884 63.0
HFD2_k127_1114144_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 565.0
HFD2_k127_1114144_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 530.0
HFD2_k127_1114144_2 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004272 267.0
HFD2_k127_1114144_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000001209 96.0
HFD2_k127_1114144_4 Protein of unknown function, DUF488 - - - 0.000002706 58.0
HFD2_k127_1114144_5 Thrombospondin type 3 repeat - - - 0.000004629 49.0
HFD2_k127_1115345_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 506.0
HFD2_k127_1115345_1 Belongs to the glycosyl hydrolase 18 family K01183 - 3.2.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 488.0
HFD2_k127_1115345_2 Iron-containing alcohol dehydrogenase K00096 - 1.1.1.261 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 461.0
HFD2_k127_1115345_3 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005339 275.0
HFD2_k127_1115345_4 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00002565 55.0
HFD2_k127_1120698_0 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase - - - 0.000000000000000000000000000000000000000000001021 183.0
HFD2_k127_1120698_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000266 124.0
HFD2_k127_1120698_2 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000002383 108.0
HFD2_k127_1127694_0 quinone binding K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 420.0
HFD2_k127_1127694_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 377.0
HFD2_k127_1127694_2 PFAM MCP methyltransferase, CheR-type K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000003323 229.0
HFD2_k127_1127694_3 4Fe-4S binding domain K14091 - - 0.00000000000000000000000000000000000000000000000003645 187.0
HFD2_k127_1127694_4 spore germination K00442,K08315 - 3.4.23.51 0.0000000000000000000000006693 111.0
HFD2_k127_1127694_5 PFAM CheW domain protein K03408 - - 0.000000000000000001864 92.0
HFD2_k127_1134016_0 spore germination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002489 285.0
HFD2_k127_1134016_1 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000002035 125.0
HFD2_k127_1137044_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004641 263.0
HFD2_k127_1137044_1 type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.00000000000000000001239 101.0
HFD2_k127_1137044_2 Transcriptional regulator - - - 0.00005282 56.0
HFD2_k127_1137044_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00008807 55.0
HFD2_k127_1140020_0 adenylate kinase activity K00939,K18532 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000001086 250.0
HFD2_k127_1140020_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000005374 239.0
HFD2_k127_1140020_2 COG1136 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000003891 156.0
HFD2_k127_1149176_0 ABC1 family - - - 0.00000000000000000000000000000000000000000002815 170.0
HFD2_k127_1149176_1 PFAM transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.000000000000000000000000001205 115.0
HFD2_k127_1155278_0 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000001137 223.0
HFD2_k127_1155278_1 abc transporter permease protein K02026 - - 0.00000000000000000000000000000000000000000000004016 182.0
HFD2_k127_1155278_2 PFAM extracellular solute-binding protein family 1 K02027,K10236 - - 0.00000000000000008942 93.0
HFD2_k127_1157479_0 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 537.0
HFD2_k127_1162065_0 Belongs to the glycosyl hydrolase 43 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 451.0
HFD2_k127_1162065_1 ABC transporter K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 331.0
HFD2_k127_1162065_2 ROK family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009196 308.0
HFD2_k127_1162065_3 Sugar ABC transporter permease K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 298.0
HFD2_k127_1162065_4 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000006754 133.0
HFD2_k127_1168589_0 hydrolase, family 65, central catalytic K15923 - 3.2.1.51 6.368e-280 878.0
HFD2_k127_1168589_1 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 411.0
HFD2_k127_1168589_10 alpha-ribazole phosphatase activity K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000002014 177.0
HFD2_k127_1168589_11 ABC-type transport system involved in multi-copper enzyme maturation, permease K01992 - - 0.000000000000000000000000000000000000562 150.0
HFD2_k127_1168589_12 PFAM WD domain, G-beta repeat - - - 0.000000000000000000002242 100.0
HFD2_k127_1168589_13 - - - - 0.0000000000000000001698 91.0
HFD2_k127_1168589_14 WD repeat-containing protein K14963 GO:0000123,GO:0000723,GO:0001085,GO:0001501,GO:0001654,GO:0002682,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005671,GO:0005737,GO:0005815,GO:0005856,GO:0005929,GO:0006109,GO:0006111,GO:0006139,GO:0006259,GO:0006325,GO:0006338,GO:0006342,GO:0006348,GO:0006355,GO:0006357,GO:0006464,GO:0006473,GO:0006475,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0007275,GO:0007399,GO:0007423,GO:0007444,GO:0007482,GO:0007568,GO:0008134,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008340,GO:0008757,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010259,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010564,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0010676,GO:0010906,GO:0010907,GO:0015630,GO:0016043,GO:0016278,GO:0016279,GO:0016458,GO:0016569,GO:0016570,GO:0016571,GO:0016573,GO:0016740,GO:0016741,GO:0018022,GO:0018024,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019222,GO:0019538,GO:0022008,GO:0022607,GO:0030030,GO:0030031,GO:0030154,GO:0030162,GO:0030182,GO:0031175,GO:0031248,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031331,GO:0031974,GO:0031981,GO:0032200,GO:0032259,GO:0032268,GO:0032270,GO:0032434,GO:0032436,GO:0032501,GO:0032502,GO:0032991,GO:0034641,GO:0034708,GO:0034968,GO:0035064,GO:0035097,GO:0035216,GO:0035295,GO:0035947,GO:0035948,GO:0036064,GO:0036211,GO:0040029,GO:0042054,GO:0042176,GO:0042393,GO:0042592,GO:0042995,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043255,GO:0043412,GO:0043414,GO:0043543,GO:0043687,GO:0043966,GO:0043967,GO:0043981,GO:0043982,GO:0043984,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044441,GO:0044446,GO:0044451,GO:0044463,GO:0044464,GO:0044545,GO:0044665,GO:0044666,GO:0044782,GO:0045595,GO:0045637,GO:0045652,GO:0045722,GO:0045732,GO:0045814,GO:0045862,GO:0045892,GO:0045893,GO:0045913,GO:0045934,GO:0045935,GO:0045944,GO:0046483,GO:0048188,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048666,GO:0048699,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0048869,GO:0050789,GO:0050793,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051239,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051445,GO:0051568,GO:0051726,GO:0060249,GO:0060255,GO:0060271,GO:0060290,GO:0060429,GO:0061136,GO:0062012,GO:0062013,GO:0065007,GO:0065008,GO:0070013,GO:0070925,GO:0071339,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0120025,GO:0120031,GO:0120036,GO:0120038,GO:0140030,GO:0140034,GO:0140096,GO:1900402,GO:1901360,GO:1901564,GO:1901800,GO:1902493,GO:1902494,GO:1902562,GO:1902679,GO:1902680,GO:1903050,GO:1903052,GO:1903341,GO:1903362,GO:1903364,GO:1903506,GO:1903507,GO:1903508,GO:1903706,GO:1990234,GO:2000026,GO:2000058,GO:2000060,GO:2000112,GO:2000113,GO:2000241,GO:2001141 - 0.0002182 52.0
HFD2_k127_1168589_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008045 338.0
HFD2_k127_1168589_3 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 308.0
HFD2_k127_1168589_4 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002308 241.0
HFD2_k127_1168589_5 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000009302 234.0
HFD2_k127_1168589_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000004715 218.0
HFD2_k127_1168589_7 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000009004 212.0
HFD2_k127_1168589_8 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000009509 203.0
HFD2_k127_1168589_9 Protein of unknown function (DUF1706) - - - 0.000000000000000000000000000000000000000000000000000992 186.0
HFD2_k127_1173063_0 PFAM Cna B domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005133 389.0
HFD2_k127_1173063_1 metallopeptidase activity - - - 0.0000000000000000000000000001521 135.0
HFD2_k127_1173063_2 30S ribosomal protein S23 - - - 0.000000000000000000003204 97.0
HFD2_k127_1177505_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006987 301.0
HFD2_k127_1177505_1 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000008719 139.0
HFD2_k127_1177505_2 Domain of unknown function (DUF4386) - - - 0.0000000000000002363 83.0
HFD2_k127_1177505_3 transcriptional regulator, LuxR family - - - 0.000003212 54.0
HFD2_k127_1186696_0 Integrase catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 314.0
HFD2_k127_1186696_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002219 271.0
HFD2_k127_1186696_2 transposition, DNA-mediated K02529,K20971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001989 273.0
HFD2_k127_1186696_3 PFAM transposase, IS4 family protein - - - 0.00000000000002145 76.0
HFD2_k127_1186696_4 Alpha-L-fucosidase K01206 - 3.2.1.51 0.0000001544 53.0
HFD2_k127_1187587_0 TAP-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000007806 232.0
HFD2_k127_1187587_1 alpha/beta hydrolase fold K01259 - 3.4.11.5 0.000000000003405 71.0
HFD2_k127_11924_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000002179 238.0
HFD2_k127_11924_1 Peptidoglycan-binding domain 1 protein K01233 - 3.2.1.132 0.000000000000001469 88.0
HFD2_k127_1198180_0 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 301.0
HFD2_k127_1198180_1 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000027 241.0
HFD2_k127_1198180_2 Competence protein K06198 - - 0.0002032 50.0
HFD2_k127_1198180_3 4-vinyl reductase, 4VR - - - 0.0002482 51.0
HFD2_k127_1200155_0 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 572.0
HFD2_k127_1200155_1 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 494.0
HFD2_k127_1200155_2 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 408.0
HFD2_k127_1200155_3 COGs COG2382 Enterochelin esterase K07214 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001171 288.0
HFD2_k127_1200155_4 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000005526 248.0
HFD2_k127_1200155_5 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 - 0.00000000000000000000000000000000000000000000000001084 206.0
HFD2_k127_1200155_6 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.0000000000000000000000000000000001223 145.0
HFD2_k127_1200155_7 YGGT family - - - 0.00000000000000001129 88.0
HFD2_k127_1200155_8 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.0000000000002449 79.0
HFD2_k127_1200155_9 Diguanylate cyclase - - - 0.000000000848 72.0
HFD2_k127_1208621_0 Carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 466.0
HFD2_k127_1208621_1 - - - - 0.00000000000000000000000000000000006679 141.0
HFD2_k127_1222977_0 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 447.0
HFD2_k127_1222977_1 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 405.0
HFD2_k127_1222977_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 313.0
HFD2_k127_1222977_3 Cupredoxin-like domain K02275 - 1.9.3.1 0.0000000000001185 82.0
HFD2_k127_1222977_4 Protein of unknown function (DUF2933) - - - 0.0000000000003594 73.0
HFD2_k127_1222977_5 ABC1 family K03688 - - 0.000000003026 61.0
HFD2_k127_1222977_6 permease K07243 - - 0.000000007237 67.0
HFD2_k127_1222977_7 Protein of unknown function (DUF1573) - - - 0.0003987 44.0
HFD2_k127_1228671_0 PFAM RNA binding S1 domain protein K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 359.0
HFD2_k127_1228671_1 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004327 278.0
HFD2_k127_1228671_2 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004384 263.0
HFD2_k127_1228671_3 Protein of unknown function (DUF952) - - - 0.00000000000000000000008975 104.0
HFD2_k127_1228671_4 Dolichyl-phosphate-mannose-protein mannosyltransferase K14340 - - 0.00000000000006255 85.0
HFD2_k127_1228671_5 PFAM Forkhead-associated protein - - - 0.000000006662 64.0
HFD2_k127_1231757_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 477.0
HFD2_k127_1231757_1 PFAM WD40 repeat, subgroup - - - 0.00000000000000000000000000000000000000000000000000000000000006806 235.0
HFD2_k127_1231757_2 LUD domain K00782 - - 0.000000000002419 68.0
HFD2_k127_1236743_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004785 355.0
HFD2_k127_1236743_2 Protein of unknown function (DUF3352) - - - 0.000141 54.0
HFD2_k127_1242394_0 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 8.151e-254 793.0
HFD2_k127_1242394_1 Cellobiose phosphorylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000276 247.0
HFD2_k127_1242394_2 Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source - - - 0.00000000000000000000000000000000000000000000000000000005121 199.0
HFD2_k127_1242524_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000003516 229.0
HFD2_k127_1242524_1 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.000000000000000000000000000000000001838 147.0
HFD2_k127_1242524_2 PFAM NHL repeat containing protein K13735 - - 0.000000000000000000001203 112.0
HFD2_k127_1259545_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 307.0
HFD2_k127_1259545_1 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001232 266.0
HFD2_k127_1259545_2 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000001791 244.0
HFD2_k127_1259545_3 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000001375 195.0
HFD2_k127_1259545_4 CAAX protease self-immunity K07052 - - 0.0000000000000000000000008135 116.0
HFD2_k127_1262364_0 Belongs to the 'phage' integrase family K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 300.0
HFD2_k127_1262364_1 cell envelope-related transcriptional attenuator - - - 0.0000000000000000000000000000000000000000000000000002066 205.0
HFD2_k127_1262364_2 LysM domain - - - 0.000000000000000001399 92.0
HFD2_k127_1262364_3 Two component regulator propeller - - - 0.00000000000000001044 96.0
HFD2_k127_1267944_0 WD domain, G-beta repeat - - - 4.952e-244 802.0
HFD2_k127_1267944_1 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009653 525.0
HFD2_k127_1267944_10 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000001043 170.0
HFD2_k127_1267944_11 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000000000000000000000000000000004895 188.0
HFD2_k127_1267944_2 helix-turn-helix- domain containing protein AraC type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 466.0
HFD2_k127_1267944_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 382.0
HFD2_k127_1267944_4 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 377.0
HFD2_k127_1267944_5 Caspase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 352.0
HFD2_k127_1267944_6 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 342.0
HFD2_k127_1267944_7 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 282.0
HFD2_k127_1267944_8 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009893 271.0
HFD2_k127_1267944_9 phosphate transport system permease K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002786 272.0
HFD2_k127_1271844_0 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00819,K00821 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.11,2.6.1.13,2.6.1.17 5.267e-214 669.0
HFD2_k127_1271844_1 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 394.0
HFD2_k127_1271844_2 alanine dehydrogenase activity K00259 GO:0000286,GO:0001666,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009628,GO:0009653,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030154,GO:0030312,GO:0030435,GO:0032502,GO:0036293,GO:0043436,GO:0043934,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048646,GO:0048856,GO:0048869,GO:0050896,GO:0055114,GO:0070482,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 331.0
HFD2_k127_1271844_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000006604 200.0
HFD2_k127_1277468_0 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000008771 233.0
HFD2_k127_1277468_1 phosphate transport regulator (Distant homolog of PhoU) K07220 - - 0.0000000000000000000000000000000000000000000286 169.0
HFD2_k127_1277468_2 Cytochrome c K07245,K14166 - - 0.0000000000000000000000006832 105.0
HFD2_k127_127951_0 cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002652 270.0
HFD2_k127_127951_1 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.000000000000000000000000000000000000000000000000000000158 203.0
HFD2_k127_127951_2 PFAM ABC transporter related K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000008682 192.0
HFD2_k127_1283253_0 nucleoside 2-deoxyribosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005354 256.0
HFD2_k127_1283253_1 Polysaccharide deacetylase - - - 0.000000000000000000000000000000002798 134.0
HFD2_k127_1283253_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000004619 129.0
HFD2_k127_1283253_3 Catalyzes the dehydration of D-mannonate K01686 - 4.2.1.8 0.0000000001619 61.0
HFD2_k127_1295630_0 PFAM Binding-protein-dependent transport system inner membrane component K05814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 310.0
HFD2_k127_1295630_1 PFAM Binding-protein-dependent transport system inner membrane component K05815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 295.0
HFD2_k127_1295630_2 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000001808 78.0
HFD2_k127_1298557_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002389 293.0
HFD2_k127_1298557_1 PFAM Integrase - - - 0.000003178 56.0
HFD2_k127_1300985_0 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 585.0
HFD2_k127_1300985_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 454.0
HFD2_k127_1300985_2 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000008059 202.0
HFD2_k127_1300985_3 exodeoxyribonuclease I activity - - - 0.000000000000000000000000000000000004968 154.0
HFD2_k127_1300985_4 Histidine kinase K07652 - 2.7.13.3 0.00000000000001116 76.0
HFD2_k127_1300985_5 - - - - 0.0000000003911 67.0
HFD2_k127_1300985_6 WD domain, G-beta repeat - - - 0.000000002489 69.0
HFD2_k127_1300985_7 Yip1 domain - - - 0.00007821 53.0
HFD2_k127_1304542_0 extracellular solute-binding protein, family 1 K02027 - - 0.00000002577 66.0
HFD2_k127_1304542_1 PFAM extracellular solute-binding protein family 1 K02027 - - 0.0001918 54.0
HFD2_k127_1310753_0 Transposase IS66 family K07484 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005126 261.0
HFD2_k127_1310753_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000001001 240.0
HFD2_k127_1310753_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000000001519 223.0
HFD2_k127_1310753_3 Leucine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000001016 197.0
HFD2_k127_1310753_4 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000001194 193.0
HFD2_k127_1310753_5 Integrase core domain - - - 0.0000000000000000000000000000000001958 137.0
HFD2_k127_1310753_6 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000001232 116.0
HFD2_k127_1310753_7 protein-S-isoprenylcysteine methyltransferase - - - 0.00000000000004389 80.0
HFD2_k127_1312358_0 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 362.0
HFD2_k127_1312358_1 family 4 K01222,K01232 - 3.2.1.122,3.2.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000007999 258.0
HFD2_k127_1312358_2 SIS domain K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000002201 215.0
HFD2_k127_1312358_3 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000002088 209.0
HFD2_k127_1312358_4 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000001698 143.0
HFD2_k127_1312358_5 Transcriptional regulator sugar kinase K00845 - 2.7.1.2 0.00000000000000000000000000000000001239 141.0
HFD2_k127_1312358_6 PFAM Glucose-6-phosphate isomerase K06859 - 5.3.1.9 0.000000000000000000000000002964 121.0
HFD2_k127_1327539_0 Amidohydrolase family K01464,K01466 - 3.5.2.2,3.5.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 363.0
HFD2_k127_1327539_1 TIR domain - - - 0.000000000000000000000000000000000000000000000001996 187.0
HFD2_k127_1327539_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000003307 172.0
HFD2_k127_1327539_3 Transcriptional regulatory protein, C terminal K07658 - - 0.00000000000000000000000000000000008341 136.0
HFD2_k127_1327539_4 peptidase dimerisation domain protein - - - 0.00000000000003519 74.0
HFD2_k127_1327539_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000009986 60.0
HFD2_k127_1330176_0 FGGY family of carbohydrate kinases, N-terminal domain - - - 1.62e-247 772.0
HFD2_k127_1330176_1 Molecular chaperone. Has ATPase activity K04079 - - 3.467e-208 664.0
HFD2_k127_1330176_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 477.0
HFD2_k127_1330176_3 Peptidase dimerisation domain protein K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 368.0
HFD2_k127_1330176_4 polysaccharide catabolic process K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 319.0
HFD2_k127_1330176_5 N-terminal TM domain of oligopeptide transport permease C K15582 - - 0.0000000000000000000000000000000000000000000000000000000005139 213.0
HFD2_k127_1330176_6 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000003915 93.0
HFD2_k127_1333824_0 S-(hydroxymethyl)glutathione dehydrogenase activity K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 432.0
HFD2_k127_1333824_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 318.0
HFD2_k127_1333824_2 pfam nudix K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000003942 166.0
HFD2_k127_1333824_3 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.000000000000000005439 92.0
HFD2_k127_1333824_4 Chitinase class I K03791 - - 0.0000000000000002405 91.0
HFD2_k127_1333824_5 Ureidoglycolate lyase - - - 0.0000228 50.0
HFD2_k127_1337405_0 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.000000000000000000000000000000000000000000000000000000000000004142 244.0
HFD2_k127_1341354_0 ATPases associated with a variety of cellular activities K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000958 443.0
HFD2_k127_1341354_1 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 443.0
HFD2_k127_1341354_2 Shikimate quinate 5-dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007913 373.0
HFD2_k127_1341354_3 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000005656 228.0
HFD2_k127_1341354_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000006148 112.0
HFD2_k127_1341354_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000004761 107.0
HFD2_k127_1343120_0 PFAM Cytochrome C assembly protein K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 488.0
HFD2_k127_1343120_1 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.0000000000000000000000000000000000000191 151.0
HFD2_k127_1343120_2 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000001344 124.0
HFD2_k127_1343120_3 subunit of a heme lyase K02200 - - 0.0000000000000000008773 94.0
HFD2_k127_1343120_4 Cytochrome c - - - 0.000000000008393 78.0
HFD2_k127_1343120_5 Two component transcriptional regulator, LuxR family - - - 0.00000000004904 66.0
HFD2_k127_1344659_0 PFAM Binding-protein-dependent transport system inner membrane component K02050 - - 1.681e-251 788.0
HFD2_k127_1344659_1 ABC nitrate sulfonate bicarbonate family transporter, ATPase subunit K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 580.0
HFD2_k127_1344659_2 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005924 321.0
HFD2_k127_1344659_3 GtrA-like protein - - - 0.0000000000000000000000000000000000006849 146.0
HFD2_k127_1347865_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 497.0
HFD2_k127_1347865_1 histidine kinase, dimerisation and phosphoacceptor region K02480 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000807 460.0
HFD2_k127_1347865_2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 459.0
HFD2_k127_1347865_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00016 - 1.1.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 447.0
HFD2_k127_1347865_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009408 334.0
HFD2_k127_1347865_5 Protein of unknown function DUF116 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 333.0
HFD2_k127_1347865_6 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000527 274.0
HFD2_k127_1347865_7 PFAM regulatory protein TetR - - - 0.0000000000002144 78.0
HFD2_k127_1354702_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000008291 265.0
HFD2_k127_1354702_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000005658 66.0
HFD2_k127_136607_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 451.0
HFD2_k127_136607_1 Nacht domain K06147 - - 0.0000000000000000000000000000001815 137.0
HFD2_k127_136607_2 Beta-lactamase - - - 0.0000000000000000000000000001959 118.0
HFD2_k127_136607_3 translation initiation factor activity - - - 0.000000000000000000000000007175 123.0
HFD2_k127_136607_4 regulation of cell shape K04074,K07484 - - 0.000000000000000994 83.0
HFD2_k127_136607_5 Beta-lactamase - - - 0.00002134 54.0
HFD2_k127_136607_6 TIR domain - - - 0.00007138 47.0
HFD2_k127_136607_7 Inositol monophosphatase K01092 - 3.1.3.25 0.0002994 52.0
HFD2_k127_1377181_0 NAD(P)H-binding K01784,K02473 - 5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 312.0
HFD2_k127_1377181_1 PFAM glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001804 288.0
HFD2_k127_1377181_2 Acyl transferase domain K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008364 282.0
HFD2_k127_1377181_3 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000004385 73.0
HFD2_k127_138974_0 Polysulphide reductase, NrfD K00185 - - 8.441e-194 613.0
HFD2_k127_138974_1 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 327.0
HFD2_k127_138974_2 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000001792 211.0
HFD2_k127_138974_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000003101 211.0
HFD2_k127_1394616_0 phosphatidylinositol kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002674 265.0
HFD2_k127_1394616_1 alpha-ribazole phosphatase activity K02226,K15634,K22305 - 3.1.3.3,3.1.3.73,5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000048 219.0
HFD2_k127_1394616_2 Bacterial membrane protein YfhO - - - 0.00000000000000000000000000000000000000008277 173.0
HFD2_k127_1394616_3 Protein of unknown function (DUF3090) - - - 0.0000000000000000000000000000000000473 139.0
HFD2_k127_1394616_5 Protein of unknown function (DUF3090) - - - 0.000002143 57.0
HFD2_k127_1394616_6 Citrate transporter - - - 0.0001238 49.0
HFD2_k127_1396655_0 - - - - 0.00000000000000000000000000000000000000000000009199 183.0
HFD2_k127_1396655_1 Glycogen synthase K20812 - 2.4.1.242 0.0000004643 63.0
HFD2_k127_1402257_0 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 355.0
HFD2_k127_1402257_1 Neutral zinc metallopeptidase K07054 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 306.0
HFD2_k127_1402257_2 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000002011 151.0
HFD2_k127_1402423_0 WD domain, G-beta repeat - - - 0.0000000000000000000000000000000000004927 162.0
HFD2_k127_1402423_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000009634 122.0
HFD2_k127_1402423_2 Cysteine-rich secretory protein family - - - 0.000000000000000000005385 106.0
HFD2_k127_1402423_3 PFAM extracellular solute-binding protein family 1 K02027 - - 0.0000000000007124 83.0
HFD2_k127_1402423_4 PFAM extracellular solute-binding protein family 1 K02027,K10188 - - 0.0000002335 64.0
HFD2_k127_1402423_5 Integrase catalytic - - - 0.000611 46.0
HFD2_k127_1424249_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 374.0
HFD2_k127_1424249_1 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 344.0
HFD2_k127_1424249_2 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000006541 249.0
HFD2_k127_1424249_3 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000007564 225.0
HFD2_k127_1444003_0 Histidine kinase - - - 0.000000000000000000000000000000000000000001002 179.0
HFD2_k127_145164_0 PFAM alpha-L-arabinofuranosidase domain protein K01209 - 3.2.1.55 3.278e-220 692.0
HFD2_k127_145164_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 441.0
HFD2_k127_145164_2 Glycosyl hydrolases family 43 K06113 - 3.2.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 391.0
HFD2_k127_145164_3 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006954 354.0
HFD2_k127_145164_4 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000217 282.0
HFD2_k127_145164_5 PFAM binding-protein-dependent transport systems inner membrane component K02025,K05814 - - 0.0000000000000000000000000000000000000000000000000000005291 195.0
HFD2_k127_145164_6 translation initiation inhibitor, yjgF family - - - 0.00000000000001208 80.0
HFD2_k127_145164_7 COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases - - - 0.00000006605 54.0
HFD2_k127_1461561_0 Stage II sporulation protein M - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001582 279.0
HFD2_k127_1461561_1 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843,K02849 - - 0.00000000000000000000000000000000000000000000000000000000000001195 226.0
HFD2_k127_1461561_2 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000001906 203.0
HFD2_k127_1461561_3 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000193 199.0
HFD2_k127_1461561_4 oxidoreductases (related to aryl-alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000001644 174.0
HFD2_k127_1461561_5 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000001132 164.0
HFD2_k127_1461561_6 PFAM RDD domain containing protein - - - 0.00000000000000000000000000000000002231 145.0
HFD2_k127_1461561_7 COG3209 Rhs family protein - - - 0.00000000000000000000000000003069 135.0
HFD2_k127_1461561_8 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000007083 117.0
HFD2_k127_1461561_9 Glyco_18 - - - 0.00003192 55.0
HFD2_k127_1465695_0 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 449.0
HFD2_k127_1465695_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000009554 250.0
HFD2_k127_1465695_2 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000001735 111.0
HFD2_k127_1465695_3 cellulose binding - - - 0.000000000000000000003013 111.0
HFD2_k127_1469773_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000004886 94.0
HFD2_k127_1478643_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 383.0
HFD2_k127_1478643_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000003186 222.0
HFD2_k127_1478643_2 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000002156 133.0
HFD2_k127_1478643_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000001149 104.0
HFD2_k127_1478643_4 - - - - 0.00000009396 63.0
HFD2_k127_148449_0 PFAM glycosyl transferase, family 51 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 407.0
HFD2_k127_148449_1 alpha-galactosidase K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000008158 254.0
HFD2_k127_1492452_0 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002894 266.0
HFD2_k127_1492452_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000267 240.0
HFD2_k127_1492452_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000008016 218.0
HFD2_k127_1492452_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000002402 193.0
HFD2_k127_1492452_4 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000001982 162.0
HFD2_k127_1492452_5 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000003729 106.0
HFD2_k127_1492452_6 Psort location Cytoplasmic, score - - - 0.00000196 59.0
HFD2_k127_1492452_7 DNA RNA non-specific endonuclease K01173 - - 0.0007747 43.0
HFD2_k127_1504954_0 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000002924 188.0
HFD2_k127_1504954_1 protein histidine kinase activity K01768,K02484,K07636,K10681,K10819,K18350,K20487 - 2.7.13.3,4.6.1.1 0.00000000000000000000000000000000000000000000000006815 201.0
HFD2_k127_1504954_2 phosphorelay signal transduction system K07667 - - 0.000000000000000000000000000001427 124.0
HFD2_k127_1518043_0 PFAM FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 586.0
HFD2_k127_1518043_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 479.0
HFD2_k127_1518043_2 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000003249 113.0
HFD2_k127_1519915_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000503 583.0
HFD2_k127_1519915_1 response regulator, receiver K11527 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000001844 206.0
HFD2_k127_1519915_3 acetyltransferase - - - 0.00008328 46.0
HFD2_k127_1519915_4 Acetyltransferase (GNAT) domain - - - 0.0009509 49.0
HFD2_k127_1520563_0 PFAM glycosyl transferase, family 51 - - - 6.764e-225 732.0
HFD2_k127_1520563_1 Acyl-CoA dehydrogenase, N-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 400.0
HFD2_k127_1520563_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001087 250.0
HFD2_k127_1520563_3 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000001099 171.0
HFD2_k127_1520563_4 PFAM Forkhead-associated protein - - - 0.0000000000000003635 84.0
HFD2_k127_1520563_5 Histidine kinase - - - 0.00000000000003146 85.0
HFD2_k127_1528827_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 476.0
HFD2_k127_1528827_1 Putative stress-induced transcription regulator - - - 0.00000000000000000000000000000000000000001775 160.0
HFD2_k127_1530869_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 487.0
HFD2_k127_1530869_1 ATP synthesis coupled electron transport K00336 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 465.0
HFD2_k127_1530869_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000001248 224.0
HFD2_k127_1530869_3 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000003853 169.0
HFD2_k127_1530869_4 FR47-like protein - - - 0.000000000004981 74.0
HFD2_k127_1531066_0 Proton-conducting membrane transporter K05568,K12137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002871 300.0
HFD2_k127_1531066_1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.000000000000000000000002543 107.0
HFD2_k127_1531066_2 Domain related to MnhB subunit of Na+/H+ antiporter K05566 - - 0.000000000000000000000003213 108.0
HFD2_k127_1531066_3 Na+/H+ antiporter subunit K05571 - - 0.00000000000000000000006098 102.0
HFD2_k127_1531066_4 COG0531 Amino acid transporters - - - 0.000000000000000000001467 109.0
HFD2_k127_1531066_5 PFAM Na H ion antiporter subunit K05569 - - 0.00000000000000000005956 97.0
HFD2_k127_1531066_6 Domain of unknown function (DUF4040) - - - 0.000000000003277 71.0
HFD2_k127_1531066_7 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.000000000005743 69.0
HFD2_k127_1531066_8 Sodium:sulfate symporter transmembrane region - - - 0.0000000001906 64.0
HFD2_k127_1531066_9 Membrane bound hydrogenase - - - 0.0000003478 55.0
HFD2_k127_1533464_0 COGs COG1131 ABC-type multidrug transport system ATPase component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 348.0
HFD2_k127_1533464_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000002534 150.0
HFD2_k127_1533464_2 AntiSigma factor - - - 0.0000000000000001508 90.0
HFD2_k127_1540675_0 Histidine kinase K07680,K07778,K11617,K14988 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007042 342.0
HFD2_k127_1540675_1 COG3316 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000001752 176.0
HFD2_k127_1540675_3 response regulator - - - 0.0000000000005512 72.0
HFD2_k127_1543390_0 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002093 273.0
HFD2_k127_1543390_1 Domain of unknown function (DUF4062) - - - 0.000000000001594 81.0
HFD2_k127_1544158_0 PFAM VanW family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 444.0
HFD2_k127_1544158_1 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000514 310.0
HFD2_k127_1544158_10 - - - - 0.000000147 58.0
HFD2_k127_1544158_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0006153 52.0
HFD2_k127_1544158_2 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001027 271.0
HFD2_k127_1544158_3 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000009848 221.0
HFD2_k127_1544158_4 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000554 163.0
HFD2_k127_1544158_5 PFAM AAA-4 family protein K03655 - 3.6.4.12 0.00000000000000000000000000000000000002675 147.0
HFD2_k127_1544158_6 Motility response receiver histidine kinase - - - 0.00000000000000000000000000233 125.0
HFD2_k127_1544158_7 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000001799 103.0
HFD2_k127_1544158_8 aspartic-type endopeptidase activity K02236,K02506,K02654 - 3.4.23.43 0.000000000003439 76.0
HFD2_k127_1544158_9 zinc-ribbon domain - - - 0.00000000004511 70.0
HFD2_k127_154505_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.000000000000000000000000000000000000000000000000000000000000009075 226.0
HFD2_k127_154505_1 peptide deformylase activity K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000002021 212.0
HFD2_k127_154505_2 ATP-dependent transcriptional regulator, MalT-like, LuxR family K03556 - - 0.00000000007262 69.0
HFD2_k127_154505_3 ATP-dependent transcriptional regulator, MalT-like, LuxR family K03556 - - 0.00000003408 57.0
HFD2_k127_1553751_0 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000602 426.0
HFD2_k127_1553751_1 intracellular signal transduction - - - 0.000000000000000001668 98.0
HFD2_k127_1553751_2 self proteolysis - - - 0.0000000001399 75.0
HFD2_k127_1553751_3 sh3 domain protein - - - 0.00005989 57.0
HFD2_k127_1556339_0 Protein tyrosine kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000007494 271.0
HFD2_k127_1556339_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000001608 184.0
HFD2_k127_1563201_0 Metallo-beta-lactamase superfamily domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 574.0
HFD2_k127_1563201_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 296.0
HFD2_k127_1563201_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.0000000000000000000000000005648 120.0
HFD2_k127_1572359_0 TAP-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009155 327.0
HFD2_k127_1572359_1 PFAM beta-lactamase - - - 0.000000000000000000000000000865 119.0
HFD2_k127_1575376_0 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 336.0
HFD2_k127_1575376_1 Tetratricopeptide repeat - - - 0.0000000000000167 85.0
HFD2_k127_1575728_0 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 1.756e-208 658.0
HFD2_k127_1575728_1 Major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 492.0
HFD2_k127_1575728_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001444 278.0
HFD2_k127_1575728_3 Methyltransferase domain K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000003436 102.0
HFD2_k127_1584241_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 9.666e-247 773.0
HFD2_k127_1584241_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000000000000000000000000000000000002834 147.0
HFD2_k127_1584241_2 PFAM CHAD domain containing protein - - - 0.0000000000000000000000000000000000002016 160.0
HFD2_k127_1584241_3 peptidase K21471 - - 0.000002067 55.0
HFD2_k127_1584241_4 Transcriptional regulatory protein, C terminal - - - 0.000193 55.0
HFD2_k127_1585605_0 COGs COG0488 ATPase components of ABC transporter with duplicated ATPase domains K06158,K18230 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 526.0
HFD2_k127_1585605_1 VWA domain containing CoxE-like protein K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 340.0
HFD2_k127_1585605_2 Putative stress-induced transcription regulator - - - 0.0000000000000000000000000000000000000000000001224 175.0
HFD2_k127_1585605_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000004583 99.0
HFD2_k127_1585605_4 peptidase C60 sortase A and B - - - 0.00000006996 62.0
HFD2_k127_1585605_5 Protein of unknown function (DUF1706) - - - 0.000006265 54.0
HFD2_k127_1585605_6 peptidase K01303 - 3.4.19.1 0.0001769 53.0
HFD2_k127_1586370_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 506.0
HFD2_k127_1586398_0 WD-40 repeat - - - 1.752e-196 667.0
HFD2_k127_1586398_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000004721 210.0
HFD2_k127_1586398_2 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000002428 179.0
HFD2_k127_1586398_3 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000002922 79.0
HFD2_k127_1586445_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000513 239.0
HFD2_k127_1586445_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000001005 202.0
HFD2_k127_1586445_2 ErfK ybiS ycfS ynhG family protein - - - 0.000000007501 65.0
HFD2_k127_1586445_3 Transcriptional regulatory protein, C terminal - - - 0.0000003744 57.0
HFD2_k127_1590774_0 Belongs to the 5'-nucleotidase family K01081,K11751 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006213,GO:0006259,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007155,GO:0007159,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009164,GO:0009166,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019362,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0022610,GO:0031974,GO:0031981,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046135,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0051186,GO:0055086,GO:0070013,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0072524,GO:0072527,GO:0072529,GO:0090304,GO:0098609,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000004363 205.0
HFD2_k127_1590774_1 PDZ DHR GLGF domain protein K08372 - - 0.00005419 53.0
HFD2_k127_1631368_0 Phosphodiester glycosidase - - - 0.0000000000000000000000000000000000009869 150.0
HFD2_k127_1631368_1 Amino-transferase class IV K00826 - 2.6.1.42 0.0000000000000000000000000001963 125.0
HFD2_k127_1631368_2 Aromatic prenyltransferase Orf2 K14129,K21341 - 2.5.1.124,2.5.1.125 0.000000000000000002329 89.0
HFD2_k127_1631368_3 - - - - 0.00000000006684 71.0
HFD2_k127_1631368_4 Aromatic prenyltransferase Orf2 K14129,K21341 - 2.5.1.124,2.5.1.125 0.00000002264 59.0
HFD2_k127_1631368_5 Aromatic prenyltransferase Orf2 K14129,K21341 - 2.5.1.124,2.5.1.125 0.0000344 48.0
HFD2_k127_1632928_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 462.0
HFD2_k127_1632928_1 Transcriptional regulatory protein, C terminal K02483,K07669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 319.0
HFD2_k127_1632928_2 Cytochrome b/b6/petB K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002098 257.0
HFD2_k127_1632928_3 Heavy metal transport detoxification protein K17686 - 3.6.3.54 0.0002039 48.0
HFD2_k127_1632928_4 Large extracellular alpha-helical protein - - - 0.0003959 49.0
HFD2_k127_163384_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 431.0
HFD2_k127_163384_1 Cadherin-like beta sandwich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 303.0
HFD2_k127_163384_2 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000001047 222.0
HFD2_k127_163384_3 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000364 173.0
HFD2_k127_163384_4 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01179,K01637 - 3.2.1.4,4.1.3.1 0.00000000000000000000000000000001907 130.0
HFD2_k127_163384_5 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000005782 127.0
HFD2_k127_1637752_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 395.0
HFD2_k127_1637752_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008934 398.0
HFD2_k127_1637752_10 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001566 203.0
HFD2_k127_1637752_11 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000002143 198.0
HFD2_k127_1637752_12 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000003022 181.0
HFD2_k127_1637752_13 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000002026 180.0
HFD2_k127_1637752_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000001231 177.0
HFD2_k127_1637752_15 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000003594 166.0
HFD2_k127_1637752_16 Predicted membrane protein (DUF2079) - - - 0.000000000000000000000000000000000000000000622 175.0
HFD2_k127_1637752_17 binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000008238 163.0
HFD2_k127_1637752_18 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000002588 152.0
HFD2_k127_1637752_19 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000286 141.0
HFD2_k127_1637752_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 306.0
HFD2_k127_1637752_20 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000006349 127.0
HFD2_k127_1637752_21 Phosphotransferase enzyme family - - - 0.000000000000000000000000001828 123.0
HFD2_k127_1637752_22 EcsC protein family - - - 0.000000000000000000001167 105.0
HFD2_k127_1637752_23 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000008221 93.0
HFD2_k127_1637752_24 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000002297 83.0
HFD2_k127_1637752_25 O-antigen polymerase K18814 - - 0.000000000001318 81.0
HFD2_k127_1637752_26 Peptidase family M23 - - - 0.0000000000248 77.0
HFD2_k127_1637752_27 Polysaccharide deacetylase K22278 - 3.5.1.104 0.00000003609 62.0
HFD2_k127_1637752_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003522 271.0
HFD2_k127_1637752_4 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007478 276.0
HFD2_k127_1637752_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000003351 258.0
HFD2_k127_1637752_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000707 244.0
HFD2_k127_1637752_7 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000001121 234.0
HFD2_k127_1637752_8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000007075 210.0
HFD2_k127_1637752_9 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000002504 210.0
HFD2_k127_1640325_0 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001487 269.0
HFD2_k127_1640325_1 Cupin - - - 0.000000000000000000000000000000000000000000000000000001033 194.0
HFD2_k127_1644093_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 571.0
HFD2_k127_1644093_1 glyoxalase III activity - - - 0.000000000000000005125 93.0
HFD2_k127_1652157_0 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 485.0
HFD2_k127_1652157_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 394.0
HFD2_k127_1652157_2 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 312.0
HFD2_k127_1652157_3 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000003405 203.0
HFD2_k127_1652157_4 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000006048 205.0
HFD2_k127_1652157_5 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568 2.7.7.68 0.00000000000000000000000000000000000000000009673 167.0
HFD2_k127_1652157_6 Thioesterase superfamily protein - - - 0.00000000000000000000000000001438 126.0
HFD2_k127_1657917_0 Glutamate synthase central domain K00265 - 1.4.1.13,1.4.1.14 0.0 1483.0
HFD2_k127_1663649_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 511.0
HFD2_k127_1663649_1 NADH-quinone oxidoreductase, chain M K00342 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 436.0
HFD2_k127_1663649_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007704 391.0
HFD2_k127_1663649_3 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000001152 111.0
HFD2_k127_1664312_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 556.0
HFD2_k127_1664312_1 regulation of response to stimulus - - - 0.000000000000000000000000000000000000000000000000000000005308 209.0
HFD2_k127_1669826_0 dehydrogenases and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 422.0
HFD2_k127_1669826_1 alpha-L-arabinofuranosidase - - - 0.000000000000000000000000000000000000000000000000001148 194.0
HFD2_k127_1669826_2 Beta-galactosidase - - - 0.000000000000000003878 89.0
HFD2_k127_1669826_3 Glycosyl hydrolases family 35 - - - 0.000009527 51.0
HFD2_k127_1669826_4 amine dehydrogenase activity - - - 0.0003718 44.0
HFD2_k127_167300_0 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007019 280.0
HFD2_k127_167300_1 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000004758 149.0
HFD2_k127_167300_2 - - - - 0.0000000002832 65.0
HFD2_k127_1677585_0 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005231 258.0
HFD2_k127_1677585_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000004746 212.0
HFD2_k127_1677585_2 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000624 184.0
HFD2_k127_1677585_3 cheY-homologous receiver domain - - - 0.0002938 48.0
HFD2_k127_1681040_0 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 329.0
HFD2_k127_1681040_1 PFAM ABC transporter K02003,K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000006608 244.0
HFD2_k127_1681040_2 PFAM glycosyl transferase family 39 - - - 0.00000002241 67.0
HFD2_k127_1681040_3 MacB-like periplasmic core domain K02004 - - 0.000004534 58.0
HFD2_k127_1690074_0 Protein of unknown function (DUF455) - - - 0.00000000000000000000000000000000000000000000000002547 196.0
HFD2_k127_1690074_1 Protein of unknown function (DUF455) - - - 0.00000000000000000000000000000000002278 148.0
HFD2_k127_1690074_2 Oxidoreductase NAD-binding domain protein K00523 - 1.17.1.1 0.000000000000005747 79.0
HFD2_k127_1690074_3 Xylose isomerase domain protein TIM barrel - - - 0.0003676 45.0
HFD2_k127_1691713_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 371.0
HFD2_k127_1691713_1 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 328.0
HFD2_k127_1691713_2 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 296.0
HFD2_k127_1691713_3 Oxidoreductase molybdopterin binding domain K00387,K07147 - 1.8.3.1 0.000000000000000000000000000000000000000000000000000000000000004277 231.0
HFD2_k127_1691713_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.0000000000000000000000000000000000000000000000000001041 193.0
HFD2_k127_1691713_5 PFAM Thioredoxin - GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000466 61.0
HFD2_k127_1691713_6 transcriptional regulator - - - 0.000000008847 63.0
HFD2_k127_169371_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0 1092.0
HFD2_k127_169371_1 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002176 287.0
HFD2_k127_169371_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003771 266.0
HFD2_k127_169371_3 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000009803 235.0
HFD2_k127_169371_4 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000001278 142.0
HFD2_k127_169371_5 Belongs to the Fur family K03711 - - 0.000000000000000000000000000006406 124.0
HFD2_k127_169371_6 MGS-like domain K01734 - 4.2.3.3 0.0000000000000000000000009235 109.0
HFD2_k127_169371_7 Chitinase class I K03791 - - 0.00000000000000000002033 104.0
HFD2_k127_169371_8 PspC domain - - - 0.000000009947 58.0
HFD2_k127_169371_9 Histidine kinase - - - 0.0005501 53.0
HFD2_k127_1699187_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000748 273.0
HFD2_k127_1699187_1 oxidoreductases (related to aryl-alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000003621 156.0
HFD2_k127_1699187_2 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000008888 108.0
HFD2_k127_1699713_0 Protein of unknown function (DUF512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 365.0
HFD2_k127_1699713_1 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000001146 230.0
HFD2_k127_1699713_2 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000007831 104.0
HFD2_k127_1699713_3 Putative cell wall binding repeat 2 K01448 - 3.5.1.28 0.00000009066 61.0
HFD2_k127_1699713_4 GGDEF domain - - - 0.000001057 59.0
HFD2_k127_1702912_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 587.0
HFD2_k127_1702912_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 316.0
HFD2_k127_1702912_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000007327 149.0
HFD2_k127_1702912_3 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.00000000000000000000001729 109.0
HFD2_k127_1702912_4 Anti-sigma-K factor rskA - - - 0.00000000000000004678 91.0
HFD2_k127_1702912_5 - - - - 0.000004121 55.0
HFD2_k127_1721633_0 PFAM IstB domain protein ATP-binding protein K02315 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 349.0
HFD2_k127_1721633_1 TIGRFAM primosome, DnaD subunit - - - 0.000000000000000000000000000000000000000000000000000003365 198.0
HFD2_k127_1721633_2 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.00000000000000000000000000000000000000000001015 165.0
HFD2_k127_1721633_3 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000007886 122.0
HFD2_k127_1727433_0 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) K00164 - 1.2.4.2 1.016e-216 694.0
HFD2_k127_1727433_1 Alcohol dehydrogenase GroES domain protein K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 308.0
HFD2_k127_1727433_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 289.0
HFD2_k127_1727433_3 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000004465 203.0
HFD2_k127_1727433_4 TrkA-N domain - - - 0.0000000000000000000000000000000858 138.0
HFD2_k127_1727433_5 cheY-homologous receiver domain K02657 - - 0.0000000000000000000000001181 111.0
HFD2_k127_1737474_0 transcriptional regulator, LuxR family - - - 7.18e-279 879.0
HFD2_k127_1737474_1 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000009239 175.0
HFD2_k127_1737474_2 Integrase catalytic - - - 0.000000000000000000000000000000000000000002055 163.0
HFD2_k127_1737474_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000003143 124.0
HFD2_k127_1737474_4 HAD-hyrolase-like - - - 0.0000000000000267 77.0
HFD2_k127_1737474_5 - - - - 0.0000000000006826 80.0
HFD2_k127_1737474_6 Family of unknown function (DUF5372) - - - 0.00000000001872 67.0
HFD2_k127_1737474_7 Transposase - - - 0.00000001937 55.0
HFD2_k127_174939_0 Aminotransferase K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 524.0
HFD2_k127_174939_1 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 0.000000000000000000000000000000000000000000000000000000000001337 214.0
HFD2_k127_174939_2 Inverse autotransporter, beta-domain K13735 - - 0.0000002626 64.0
HFD2_k127_1755410_0 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 535.0
HFD2_k127_1755410_1 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000000000001234 197.0
HFD2_k127_1755410_2 Transposase IS66 family K07484 - - 0.00000000000000000007996 94.0
HFD2_k127_1755410_3 ubiE/COQ5 methyltransferase family - - - 0.0000000000000001033 90.0
HFD2_k127_1765503_0 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 351.0
HFD2_k127_1765503_1 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000007932 111.0
HFD2_k127_1765503_2 Transcription regulator MerR DNA binding K13639 - - 0.000000000000000000000002109 114.0
HFD2_k127_1765503_3 4-amino-4-deoxy-L-arabinose transferase activity K13687 - - 0.0000000000000000000002923 111.0
HFD2_k127_1791453_0 Sugar transferase, PEP-CTERM EpsH1 system associated - - - 0.000000000000000000000000000000000000000000000002357 190.0
HFD2_k127_1791453_1 PFAM peptidase S1 and S6, chymotrypsin Hap K08070 - 1.3.1.74 0.00000003294 65.0
HFD2_k127_1798345_0 ABC transporter K09697 - 3.6.3.7 0.00000000000000000000000000000000000000000000000000000000000000004205 229.0
HFD2_k127_1798345_1 COG1668 ABC-type Na efflux pump, permease component K09696 - - 0.00000000000000001647 95.0
HFD2_k127_1803525_0 PFAM amine oxidase K02293 - 1.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006929 284.0
HFD2_k127_1803525_1 cheY-homologous receiver domain K11443 - - 0.0000000000000000000000000000000000003679 144.0
HFD2_k127_1803525_2 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.0000000000000000000000001947 122.0
HFD2_k127_1803525_3 COG2771 DNA-binding HTH domain-containing proteins - - - 0.00000000002975 76.0
HFD2_k127_1803525_4 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.0000104 57.0
HFD2_k127_1804264_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 512.0
HFD2_k127_1804264_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.00000000000000000000000000000000000000000000000000000000000186 215.0
HFD2_k127_1804264_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000006699 106.0
HFD2_k127_1804694_0 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 606.0
HFD2_k127_1804694_1 PFAM alpha beta hydrolase fold - - - 0.00005384 48.0
HFD2_k127_1806794_0 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000001179 167.0
HFD2_k127_1806794_1 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.00000000000000000000000000000000000002703 157.0
HFD2_k127_1806794_2 Thioredoxin-like - - - 0.00000000000000000000000000008168 123.0
HFD2_k127_1806794_3 ErfK ybiS ycfS ynhG family protein - - - 0.000000009949 66.0
HFD2_k127_1807118_0 PFAM glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 320.0
HFD2_k127_1807118_1 Deacylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006912 306.0
HFD2_k127_1807118_2 cellular response to dsDNA K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001087 237.0
HFD2_k127_1808162_0 Domain of unknown function (DUF4417) - - - 0.00000000000000000000000000000000000000002192 162.0
HFD2_k127_1822579_0 transposition K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 284.0
HFD2_k127_1822579_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000005945 189.0
HFD2_k127_1822579_2 - - - - 0.00000000000004433 77.0
HFD2_k127_1829609_0 Bacterial protein of unknown function (DUF899) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 320.0
HFD2_k127_1829609_1 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000000000000000000000001461 220.0
HFD2_k127_1829609_2 - - - - 0.00000000000000000000000000000000000000000004469 164.0
HFD2_k127_1829609_3 Helix-turn-helix XRE-family like proteins K07729 - - 0.00000000000000000000000000007992 119.0
HFD2_k127_1829609_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000001047 115.0
HFD2_k127_1829609_5 Activator of Hsp90 ATPase - - - 0.0000000000000000000000004 111.0
HFD2_k127_1829609_6 Protein conserved in bacteria - - - 0.00000000000000001191 85.0
HFD2_k127_1829609_7 - - - - 0.000000134 60.0
HFD2_k127_1829609_8 Zinc-binding dehydrogenase - - - 0.000002725 49.0
HFD2_k127_18316_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 603.0
HFD2_k127_18316_1 Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000001444 213.0
HFD2_k127_1832235_0 PFAM FGGY family of carbohydrate kinases, N-terminal domain K00853 - 2.7.1.16 7.934e-249 779.0
HFD2_k127_1832235_1 L-fucose isomerase, C-terminal domain - - - 5.466e-221 694.0
HFD2_k127_1832235_2 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.00000000000000000000000000000000000000000000000000000000000000002895 240.0
HFD2_k127_1832235_3 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000001274 188.0
HFD2_k127_1832235_4 membrane - - - 0.000000000000000000000000000004493 130.0
HFD2_k127_1832235_5 Transcriptional regulator K07775 - - 0.000000000000001885 81.0
HFD2_k127_1832235_6 - - - - 0.00001297 59.0
HFD2_k127_1832235_7 protein with a bacterial SH3 domain - - - 0.00005727 54.0
HFD2_k127_1832235_8 Evidence 4 Homologs of previously reported genes of - - - 0.0004732 49.0
HFD2_k127_1835056_0 InterPro IPR009342 IPR010383 IPR010403 K18675 - 2.4.1.280 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 473.0
HFD2_k127_1835056_1 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 336.0
HFD2_k127_1835056_2 Binding-protein-dependent transport system inner membrane component K02026,K05815,K10119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 316.0
HFD2_k127_1835056_3 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 310.0
HFD2_k127_1835056_4 periplasmic binding protein LacI transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 298.0
HFD2_k127_1835056_5 Binding-protein-dependent transport system inner membrane component K10118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007449 283.0
HFD2_k127_1835056_6 lactoylglutathione lyase activity K08234 - - 0.000000000000000000000000000000003048 140.0
HFD2_k127_1835056_7 Glycosyl hydrolase 36 superfamily, catalytic domain K00702 - 2.4.1.20 0.00000000000001293 77.0
HFD2_k127_1835553_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 321.0
HFD2_k127_1835553_1 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002564 248.0
HFD2_k127_1839238_0 PFAM glycoside hydrolase, family 1 K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 541.0
HFD2_k127_1839238_1 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000000002068 202.0
HFD2_k127_1839238_2 PFAM TadE family protein K12287 - - 0.0000000000000000000000000000000000000000000000000000001138 220.0
HFD2_k127_1847980_0 metalloendopeptidase activity K08602 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 489.0
HFD2_k127_1847980_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001555 282.0
HFD2_k127_1847980_2 Domain of unknown function (DUF348) - - - 0.0000000000000000000000000000000000000000000000000000000000000000008119 246.0
HFD2_k127_1847980_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000008433 235.0
HFD2_k127_1847980_4 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000001595 112.0
HFD2_k127_185051_0 PFAM gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 547.0
HFD2_k127_185051_1 Ntpase (Nacht family) K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004728 484.0
HFD2_k127_185051_2 cheY-homologous receiver domain - - - 0.0000000000000003492 83.0
HFD2_k127_185051_3 Chitinase class I K03791 - - 0.00000000003218 74.0
HFD2_k127_1863437_0 Bacterial extracellular solute-binding protein K02027 - - 0.0000001381 64.0
HFD2_k127_1863589_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 1.63e-222 718.0
HFD2_k127_1863589_1 Natural resistance-associated macrophage protein - - - 0.0000000000000001664 80.0
HFD2_k127_1867350_0 Subtilase family - - - 0.0 1149.0
HFD2_k127_1867350_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 441.0
HFD2_k127_1876355_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.621e-296 924.0
HFD2_k127_1876355_1 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 597.0
HFD2_k127_1876355_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000002291 169.0
HFD2_k127_1876355_3 PFAM response regulator receiver K03413 - - 0.0000000000000004619 82.0
HFD2_k127_1883881_0 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007648 560.0
HFD2_k127_1883881_1 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 514.0
HFD2_k127_1883881_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 437.0
HFD2_k127_1883881_3 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005521 278.0
HFD2_k127_1883881_4 ATPase-coupled phosphate ion transmembrane transporter activity K02036,K06857 - 3.6.3.27,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000001087 250.0
HFD2_k127_1883881_5 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000001912 235.0
HFD2_k127_1883881_6 TOBE domain K02019 - - 0.000000000000000000002627 95.0
HFD2_k127_188600_0 PFAM NADH flavin oxidoreductase NADH oxidase - - - 1.163e-222 698.0
HFD2_k127_188600_1 inositol 2-dehydrogenase activity - - - 2.316e-217 681.0
HFD2_k127_188600_10 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000107 208.0
HFD2_k127_188600_11 - - - - 0.00000000000000000000001827 102.0
HFD2_k127_188600_12 - - - - 0.000000000000002799 84.0
HFD2_k127_188600_13 Protein of unknown function, DUF624 - - - 0.00004794 53.0
HFD2_k127_188600_2 carbohydrate transport K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 460.0
HFD2_k127_188600_3 PFAM Glycosyl Hydrolase Family 88 K18581 - 3.2.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 450.0
HFD2_k127_188600_4 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 421.0
HFD2_k127_188600_5 glycerophosphodiester transmembrane transport K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 414.0
HFD2_k127_188600_6 PFAM binding-protein-dependent transport systems inner membrane component K02025,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 389.0
HFD2_k127_188600_7 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001338 285.0
HFD2_k127_188600_8 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000791 244.0
HFD2_k127_188600_9 Shikimate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000009382 226.0
HFD2_k127_1890716_0 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 1.274e-209 662.0
HFD2_k127_1890716_1 alcohol dehydrogenase K00008,K00060 - 1.1.1.103,1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 471.0
HFD2_k127_1890716_2 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 419.0
HFD2_k127_1890716_3 Branched-chain amino acid transport system / permease component K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 332.0
HFD2_k127_1890716_4 Branched-chain amino acid transport system / permease component K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 329.0
HFD2_k127_1890716_5 with different specificities (related to short-chain alcohol - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 316.0
HFD2_k127_1890716_6 Xylose isomerase-like TIM barrel K01805 - 5.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000009833 268.0
HFD2_k127_1890716_7 UTRA K03710 - - 0.0000000000000887 73.0
HFD2_k127_1895726_0 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 496.0
HFD2_k127_1895726_1 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 0.00000001942 56.0
HFD2_k127_1895726_2 Cytochrome c554 and c-prime - - - 0.00001083 51.0
HFD2_k127_1899557_0 synthase K00705,K06044 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576 2.4.1.25,5.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 522.0
HFD2_k127_1899557_1 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000007352 203.0
HFD2_k127_1899557_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000005907 167.0
HFD2_k127_1899557_3 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000000001356 151.0
HFD2_k127_1899557_4 - - - - 0.0000000000000000000000000297 115.0
HFD2_k127_1901067_0 Aldehyde oxidase and xanthine dehydrogenase a b hammerhead K03520,K11177 - 1.17.1.4,1.2.5.3 0.0 1237.0
HFD2_k127_1901067_1 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 338.0
HFD2_k127_1901067_2 metallochaperone-like domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000087 266.0
HFD2_k127_1901067_3 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001313 254.0
HFD2_k127_1901994_0 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 502.0
HFD2_k127_1901994_1 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 291.0
HFD2_k127_1901994_2 COG0631 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.00000000002061 69.0
HFD2_k127_1909594_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007419 313.0
HFD2_k127_1923644_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 7.979e-246 768.0
HFD2_k127_1923644_1 Belongs to the phosphoglycerate mutase family - - - 0.000000000000000000000000000000000001209 146.0
HFD2_k127_1923644_2 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K02548,K03179,K17105 - 2.5.1.39,2.5.1.42,2.5.1.74 0.000000000000000000000000000000000774 136.0
HFD2_k127_1923644_3 Calcineurin-like phosphoesterase - - - 0.0000716 54.0
HFD2_k127_19281_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 603.0
HFD2_k127_19281_1 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 318.0
HFD2_k127_19281_2 self proteolysis - - - 0.000000000000000000000000000000000000000000503 171.0
HFD2_k127_19281_3 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.000000000000000000000000000000000000000003728 158.0
HFD2_k127_19281_4 homoserine transmembrane transporter activity K06600,K06895 - - 0.0000000000000000000000000000000000000004165 158.0
HFD2_k127_19281_5 FCD - - - 0.0000000000000000008343 94.0
HFD2_k127_19281_6 Transglycosylase-like domain K21687 - - 0.00000000002168 76.0
HFD2_k127_1938452_0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term - - - 0.0 1066.0
HFD2_k127_1938452_1 Bacterial extracellular solute-binding protein K10227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 392.0
HFD2_k127_1938452_2 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 310.0
HFD2_k127_1938452_3 PhoQ Sensor K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000001961 198.0
HFD2_k127_1938452_4 MOSC domain - - - 0.000000000000000000000000000000000001094 141.0
HFD2_k127_1938452_5 WD40-like Beta Propeller Repeat - - - 0.000000973 61.0
HFD2_k127_1939617_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 359.0
HFD2_k127_1939617_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01218 - 3.2.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 329.0
HFD2_k127_1939617_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008859 304.0
HFD2_k127_1939617_3 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 308.0
HFD2_k127_1939617_4 membrane - - - 0.000394 51.0
HFD2_k127_1942862_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004755 282.0
HFD2_k127_1942862_1 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000008457 247.0
HFD2_k127_1942862_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000004524 184.0
HFD2_k127_1942862_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000005288 165.0
HFD2_k127_1942862_4 Acyl-transferase K00655,K00945 - 2.3.1.51,2.7.4.25 0.00000000000000000000000006191 117.0
HFD2_k127_1942862_5 antibiotic catabolic process - - - 0.0000000003851 73.0
HFD2_k127_1942862_6 - - - - 0.0000906 49.0
HFD2_k127_1957036_0 PFAM FGGY family of carbohydrate kinases, N-terminal domain K00853 - 2.7.1.16 6.423e-212 668.0
HFD2_k127_1957036_1 PFAM Bacterial regulatory proteins, lacI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 343.0
HFD2_k127_1966332_0 Glutamine synthetase, catalytic domain - - - 9.867e-200 630.0
HFD2_k127_1966332_1 N-formylglutamate amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 312.0
HFD2_k127_1966332_2 Isochorismatase family - - - 0.0000000000002814 71.0
HFD2_k127_1966332_3 Receptor family ligand binding region K01999 - - 0.0000007985 54.0
HFD2_k127_1979867_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 3.539e-204 666.0
HFD2_k127_1979867_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 560.0
HFD2_k127_1979867_10 Cell Wall K01448 - 3.5.1.28 0.0008567 50.0
HFD2_k127_1979867_2 PFAM Glycosyl transferase family 2 K10012 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 400.0
HFD2_k127_1979867_3 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D K01424 GO:0003674,GO:0003824,GO:0004067,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006530,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032787,GO:0033345,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:0072329,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 389.0
HFD2_k127_1979867_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 312.0
HFD2_k127_1979867_5 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000006534 167.0
HFD2_k127_1979867_6 Nodulation protein S (NodS) - - - 0.000000000000000000000000000000000001425 149.0
HFD2_k127_1979867_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000005321 79.0
HFD2_k127_1979867_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000381 60.0
HFD2_k127_1979867_9 Methionine biosynthesis protein MetW K07755 - 2.1.1.137 0.00001089 55.0
HFD2_k127_1983842_0 CoA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 343.0
HFD2_k127_1983842_1 4-vinyl reductase, 4VR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 299.0
HFD2_k127_1983842_2 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 292.0
HFD2_k127_1983842_3 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000003923 228.0
HFD2_k127_1983842_4 PFAM Stage II sporulation E family protein K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000001221 200.0
HFD2_k127_1983842_5 PFAM Roadblock LC7 family protein K07131 - - 0.00000000000000000000000000000000000000000000003781 172.0
HFD2_k127_1983842_6 Heavy-metal-associated domain K17686 - 3.6.3.54 0.0000000000000000000000000000007475 127.0
HFD2_k127_1983842_7 Membrane - - - 0.0000000000000000000000000000009184 138.0
HFD2_k127_1983842_8 O-Antigen ligase K18814 - - 0.00000000000003832 87.0
HFD2_k127_1983842_9 PFAM Bacterial regulatory protein, arsR family - - - 0.00000002161 57.0
HFD2_k127_1990707_0 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 299.0
HFD2_k127_1990707_1 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008164 260.0
HFD2_k127_1990707_2 PFAM response regulator receiver K07658 - - 0.0000000000000000000000000000000000000000000000000000006399 198.0
HFD2_k127_1990848_0 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 335.0
HFD2_k127_1990848_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000001045 197.0
HFD2_k127_1990848_2 Periplasmic copper-binding protein (NosD) - - - 0.0000002005 59.0
HFD2_k127_1990848_3 - - - - 0.0000003772 53.0
HFD2_k127_1993532_0 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 564.0
HFD2_k127_1993532_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005412 545.0
HFD2_k127_1993532_2 Fe-S oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 523.0
HFD2_k127_199911_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 3.227e-224 724.0
HFD2_k127_199911_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000002116 192.0
HFD2_k127_199911_2 protein secretion by the type VII secretion system K21104 - 3.1.1.101 0.000000512 61.0
HFD2_k127_199911_3 Protein tyrosine kinase - - - 0.000001696 50.0
HFD2_k127_2008411_0 - - - - 0.00000000000000000000000465 108.0
HFD2_k127_2008411_1 PFAM deoxynucleoside kinase - - - 0.0000000000000000001353 91.0
HFD2_k127_2008411_2 Acetyltransferase (GNAT) domain - - - 0.000000000965 70.0
HFD2_k127_2008530_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 0.0 1262.0
HFD2_k127_2008530_1 Cupredoxin-like domain - - - 0.00000000000000000000000000000000000000000000000000006084 194.0
HFD2_k127_2009037_0 Transcriptional regulator, contains sigma factor-related N-terminal domain K11531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001436 268.0
HFD2_k127_2009037_1 FGGY family of carbohydrate kinases, N-terminal domain K00880 - 2.7.1.53 0.000000000000000000000000000000000000000000000000000000000001967 220.0
HFD2_k127_2009037_2 Band 7 protein K07192 - - 0.0000000000000000000000000000000000000000000000000185 186.0
HFD2_k127_2009037_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000004301 124.0
HFD2_k127_2017212_0 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000652 526.0
HFD2_k127_2017212_1 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000001719 239.0
HFD2_k127_2017212_2 COGs COG1819 Glycosyl transferase related to UDP-glucuronosyltransferase - - - 0.0000000000000000000000000000000000007452 143.0
HFD2_k127_2038413_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008871 302.0
HFD2_k127_2038413_1 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001289 232.0
HFD2_k127_2045484_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008749 268.0
HFD2_k127_2045484_1 Protein of unknown function (DUF3048) C-terminal domain - - - 0.000000000000000000000000000004044 136.0
HFD2_k127_2045484_2 Calcium/calmodulin dependent protein kinase II association domain - - - 0.0000000000000000000000000009153 123.0
HFD2_k127_2048216_0 Amino acid permease - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 2.419e-198 637.0
HFD2_k127_2048216_1 PFAM D-galactarate dehydratase Altronate hydrolase, C terminus K01685 - 4.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 590.0
HFD2_k127_2048216_2 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000309 91.0
HFD2_k127_2048216_3 Histidine kinase K07646 - 2.7.13.3 0.0006472 48.0
HFD2_k127_204996_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 480.0
HFD2_k127_204996_1 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 471.0
HFD2_k127_204996_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000005199 219.0
HFD2_k127_204996_3 PFAM Dynamin family protein - - - 0.000000000000000000000000000000000000000000000000000000001373 222.0
HFD2_k127_204996_4 Dynamin family - - - 0.0000000000000000000000000000000000000000000000000000003137 216.0
HFD2_k127_204996_5 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000001019 141.0
HFD2_k127_2051117_0 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008182 616.0
HFD2_k127_2051117_1 Ribosomal L27 protein K02899 - - 0.00000000000000000000000000002542 119.0
HFD2_k127_2051117_2 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000006349 116.0
HFD2_k127_2052836_0 PFAM ABC transporter related K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 361.0
HFD2_k127_2052836_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009423 365.0
HFD2_k127_2052836_2 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.000000000000000000000000000000000000000000000000008763 198.0
HFD2_k127_2052836_3 Binding-protein-dependent transport system inner membrane component K02029 - - 0.000000000000000000000000000000000000000000008181 182.0
HFD2_k127_2052836_4 Histidine kinase - - - 0.000000002709 63.0
HFD2_k127_2052836_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000028 63.0
HFD2_k127_2069507_0 Glycosyl transferase WecB/TagA/CpsF family K05946 - 2.4.1.187 0.0000000000000000000000000000000000000000000000000000000000000000009573 237.0
HFD2_k127_2069507_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000002326 247.0
HFD2_k127_2069507_2 COGs COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000000000000000000000000000724 149.0
HFD2_k127_2069507_3 Forkhead associated domain - - - 0.00000000000000000439 99.0
HFD2_k127_2069507_4 Belongs to the peptidase S8 family - - - 0.00000000006553 72.0
HFD2_k127_2069507_5 - - - - 0.00000003596 63.0
HFD2_k127_2070905_0 transposition, DNA-mediated K02529,K20971 - - 0.000000000000000000000000000000000000000000000000000000000000002583 232.0
HFD2_k127_2074273_0 cellulose binding K08604,K12132 - 2.7.11.1,3.4.24.25 0.00000000000000000000003122 116.0
HFD2_k127_2074273_2 Transposase IS200 like K07491 - - 0.0001155 49.0
HFD2_k127_2089364_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000002432 192.0
HFD2_k127_2089364_1 Methyltransferase type 11 - - - 0.000000000000000000000000000000000002804 139.0
HFD2_k127_2089364_2 Belongs to the peptidase S8 family - - - 0.000000000000007935 87.0
HFD2_k127_2100972_0 PFAM Helix-turn-helix, type 11 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 338.0
HFD2_k127_2100972_1 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 302.0
HFD2_k127_2100972_2 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003129 265.0
HFD2_k127_2100972_3 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000001216 205.0
HFD2_k127_2100972_4 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.0000000000000000000000000000000000000202 149.0
HFD2_k127_2100972_5 4-vinyl reductase, 4VR - - - 0.00000003136 59.0
HFD2_k127_2101037_0 PFAM purine or other phosphorylase family 1 - - - 0.000000000000000000000000000000000000000000000000000000000000006603 219.0
HFD2_k127_2101037_1 InterPro IPR014922 - - - 0.000000000000000000000000000000000000000000000000000000000003839 213.0
HFD2_k127_2101037_2 transcriptional regulator - - - 0.0000000000000000000001796 106.0
HFD2_k127_2101037_3 transcriptional regulator - - - 0.00000000000000123 86.0
HFD2_k127_2101037_4 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000003389 81.0
HFD2_k127_2101037_5 Sigma-70, region 4 K03088 - - 0.0009153 44.0
HFD2_k127_212449_0 Fibronectin type III-like domain K05349 - 3.2.1.21 2.163e-258 817.0
HFD2_k127_212449_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000884 369.0
HFD2_k127_212449_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 293.0
HFD2_k127_212449_3 WD domain, G-beta repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000002515 250.0
HFD2_k127_212449_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000001424 126.0
HFD2_k127_212449_5 PFAM WD domain, G-beta repeat - - - 0.00000000002676 77.0
HFD2_k127_212449_6 Wd40 repeat-containing protein - - - 0.00000000004655 76.0
HFD2_k127_212449_7 transposition K07497 - - 0.000000002091 60.0
HFD2_k127_212449_8 Fibronectin type III-like domain K05349 - 3.2.1.21 0.0000004058 55.0
HFD2_k127_2129182_0 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K21103,K21460 - 2.1.1.304,2.1.1.327 0.0000000000000000000000000000000000000000000000000000000000000000001201 235.0
HFD2_k127_2134468_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007259 250.0
HFD2_k127_2134468_1 Transposase DDE domain - - - 0.000002069 59.0
HFD2_k127_2135926_0 Molydopterin dinucleotide binding domain K07306,K07812 - 1.7.2.3,1.8.5.3 0.0 1094.0
HFD2_k127_2135926_1 Fe-S-cluster-containing hydrogenase K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005277 268.0
HFD2_k127_2135926_2 molybdopterin cofactor binding K00183 - - 0.0000000000000000000000000000009831 127.0
HFD2_k127_2135926_3 PFAM cytoplasmic chaperone TorD - - - 0.000000000005404 75.0
HFD2_k127_2150859_0 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 419.0
HFD2_k127_2150859_1 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000301 239.0
HFD2_k127_2150859_2 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000001785 133.0
HFD2_k127_2150859_3 HxlR-like helix-turn-helix - GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000002475 121.0
HFD2_k127_2150859_4 translation initiation factor activity - - - 0.000000000000000000003583 108.0
HFD2_k127_2151424_0 Branched-chain amino acid transport system / permease component K10440,K17209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 376.0
HFD2_k127_2151424_1 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 288.0
HFD2_k127_2151424_2 Periplasmic binding proteins and sugar binding domain of LacI family K10439 - - 0.00000000000000000002734 94.0
HFD2_k127_2158740_0 COGs COG3547 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000137 261.0
HFD2_k127_2158740_1 PFAM Formylglycine-generating sulfatase enzyme K20333 - - 0.000000000000000000000000000000000000000000000000000000000000000006695 246.0
HFD2_k127_2158740_2 Transposase IS116/IS110/IS902 family - - - 0.0000001807 55.0
HFD2_k127_2161007_0 ATP-dependent transcriptional regulator, MalT-like, LuxR family K03556 - - 1.331e-223 729.0
HFD2_k127_2161007_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006841 571.0
HFD2_k127_2161007_10 response to heat K03668,K09914 - - 0.0000000000000003054 89.0
HFD2_k127_2161007_11 Domain of unknown function (DUF305) - - - 0.0000000000000003108 87.0
HFD2_k127_2161007_12 Ferric uptake regulator family K03711 - - 0.0000000000000003893 84.0
HFD2_k127_2161007_13 FeoC like transcriptional regulator - - - 0.0000000000006593 71.0
HFD2_k127_2161007_14 iron ion homeostasis K04758 - - 0.00000000000468 70.0
HFD2_k127_2161007_15 Tetrapyrrole (Corrin/Porphyrin) Methylases K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000002895 52.0
HFD2_k127_2161007_17 - - - - 0.0008 48.0
HFD2_k127_2161007_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 457.0
HFD2_k127_2161007_3 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 438.0
HFD2_k127_2161007_4 pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 450.0
HFD2_k127_2161007_5 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000002608 201.0
HFD2_k127_2161007_7 Protein of unknown function (DUF3455) - - - 0.0000000000000000000000001675 113.0
HFD2_k127_2161007_8 PFAM FeoA family protein K04758 - - 0.0000000000000000002098 89.0
HFD2_k127_2161007_9 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000324 94.0
HFD2_k127_2173201_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 299.0
HFD2_k127_2173201_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 291.0
HFD2_k127_2173201_2 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003545 259.0
HFD2_k127_2173201_3 COGs COG3485 Protocatechuate 3 4-dioxygenase beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000001167 239.0
HFD2_k127_2173201_4 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000004175 177.0
HFD2_k127_2181125_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 426.0
HFD2_k127_2181125_1 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000004659 218.0
HFD2_k127_2181125_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000002111 147.0
HFD2_k127_2181125_3 Involved in the TonB-independent uptake of proteins K03641 - - 0.00004089 48.0
HFD2_k127_218433_0 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 362.0
HFD2_k127_218433_1 PFAM 3-carboxy-cis,cis-muconate lactonizing enzyme K01317 - 3.4.21.10 0.000000000000000000000000000000000000000000000000000000000000000000003429 272.0
HFD2_k127_2185189_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 2.136e-202 652.0
HFD2_k127_2190712_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.552e-294 924.0
HFD2_k127_2190712_1 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000005076 271.0
HFD2_k127_2190712_2 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000004546 272.0
HFD2_k127_2190712_3 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000000000000002759 190.0
HFD2_k127_2190712_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000006579 152.0
HFD2_k127_2190712_5 Belongs to the ABC transporter superfamily K10112 - - 0.0000000001607 66.0
HFD2_k127_2203383_0 Glycosyl hydrolase family 65 central catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001379 246.0
HFD2_k127_2203383_1 Cys Met metabolism K01739,K01758,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11 0.000000000000000000000000000000000000000000000000000000000001573 215.0
HFD2_k127_2203383_2 sh3 domain protein K01448 - 3.5.1.28 0.0001568 53.0
HFD2_k127_2203647_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 507.0
HFD2_k127_2203647_1 multi-organism process - - - 0.000000000000000001361 100.0
HFD2_k127_2206947_0 FGGY family of carbohydrate kinases, N-terminal domain K00853 - 2.7.1.16 7.83e-218 687.0
HFD2_k127_2206947_1 C-terminal domain of alpha-glycerophosphate oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 532.0
HFD2_k127_2206947_2 PFAM Haloacid dehalogenase domain protein hydrolase K02566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000705 382.0
HFD2_k127_2206947_3 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000003308 160.0
HFD2_k127_2218892_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008574 412.0
HFD2_k127_2218892_1 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 308.0
HFD2_k127_2218892_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000004932 174.0
HFD2_k127_2221823_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 1.357e-299 968.0
HFD2_k127_2221823_1 FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 482.0
HFD2_k127_2221823_2 PHP domain K04486 - 3.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000158 239.0
HFD2_k127_2221823_3 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000001316 220.0
HFD2_k127_2221823_4 MBOAT, membrane-bound O-acyltransferase family K03739,K19294 - - 0.0000000000000000000000000000000000000000000000000000002947 212.0
HFD2_k127_2221823_5 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0000000000000000000000000000002075 135.0
HFD2_k127_2221823_6 Sigma factor PP2C-like phosphatases K20074 - 3.1.3.16 0.000000000000000000000002194 108.0
HFD2_k127_2221823_7 histone H2A K63-linked ubiquitination K01768 - 4.6.1.1 0.00000000000003591 80.0
HFD2_k127_2221823_8 Histidine kinase - - - 0.00000000001227 70.0
HFD2_k127_2221823_9 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000001004 61.0
HFD2_k127_2229026_0 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 592.0
HFD2_k127_2229026_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K15975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 550.0
HFD2_k127_2229026_2 Catalyzes the release of L-lysine from LysW -gamma-L- lysine K05831 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 380.0
HFD2_k127_2229026_3 PFAM isocitrate isopropylmalate dehydrogenase K05824 - 1.1.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009068 362.0
HFD2_k127_2229026_4 GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 346.0
HFD2_k127_2229026_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K16792 - 4.2.1.114,4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 328.0
HFD2_k127_2229026_6 Phospholipase/Carboxylesterase K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009526 294.0
HFD2_k127_2229026_7 Belongs to the LeuD family K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000006496 237.0
HFD2_k127_2229026_8 positive regulation of transcription, DNA-templated K09684 - - 0.00000000000000000000000000000000000000000000000000000000000001819 235.0
HFD2_k127_2229026_9 - - - - 0.00000000000006786 81.0
HFD2_k127_2229932_0 transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 482.0
HFD2_k127_2229932_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001556 276.0
HFD2_k127_2229932_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000002234 203.0
HFD2_k127_2229932_3 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000001155 188.0
HFD2_k127_2229932_4 Cys-tRNA(Pro) hydrolase activity K03976 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0043907,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000008577 149.0
HFD2_k127_2229932_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000004262 142.0
HFD2_k127_2229932_6 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000000000000586 141.0
HFD2_k127_2229932_7 - - - - 0.00000000000000000000000000000005457 132.0
HFD2_k127_2230634_0 SMART alpha amylase, catalytic sub domain K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 1.747e-197 629.0
HFD2_k127_2230634_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 556.0
HFD2_k127_2230634_2 COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase - - - 0.000000000000000000000000002786 128.0
HFD2_k127_2230634_3 Tfp pilus assembly protein FimV - - - 0.000103 53.0
HFD2_k127_2234505_0 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008188 535.0
HFD2_k127_2234505_1 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 333.0
HFD2_k127_2234505_2 - - - - 0.00000000000004164 79.0
HFD2_k127_2241810_0 PFAM fumarate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 523.0
HFD2_k127_2241810_1 ArgJ family K00620,K00930 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35,2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000002527 262.0
HFD2_k127_2241810_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000001995 104.0
HFD2_k127_224203_0 Pyridine nucleotide-disulphide oxidoreductase K05297 - 1.18.1.1 1.2e-277 881.0
HFD2_k127_224203_1 Transposase IS66 family K07484 - - 0.0000000000000000000000000000000000000000000000000000000000000000007208 235.0
HFD2_k127_224203_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000003764 249.0
HFD2_k127_224203_3 PASTA K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000000000000000000000000000000000000000000000000000006092 210.0
HFD2_k127_224203_4 PFAM Cyclic nucleotide-binding - - - 0.0000000000000000000000000003708 119.0
HFD2_k127_224203_5 PFAM Transposase IS66 family K07484 - - 0.000000000000000000004196 99.0
HFD2_k127_224203_6 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000007252 97.0
HFD2_k127_224203_7 CAAX protease self-immunity K07052 - - 0.000000000301 69.0
HFD2_k127_2243119_0 SMART AAA ATPase K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 363.0
HFD2_k127_2243119_1 PFAM thioesterase superfamily protein - - - 0.0000000000000000000000000000000000000000000006745 171.0
HFD2_k127_2249968_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000002375 135.0
HFD2_k127_2249968_1 Peptidase MA superfamily - - - 0.000000254 63.0
HFD2_k127_2249968_2 Ami_3 K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.0001577 49.0
HFD2_k127_2250172_0 Berberine and berberine like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 603.0
HFD2_k127_2250172_1 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 359.0
HFD2_k127_2250172_2 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 290.0
HFD2_k127_2250172_3 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000005809 213.0
HFD2_k127_2250172_4 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000007406 213.0
HFD2_k127_2250172_5 SnoaL-like domain - - - 0.00000000000000000000000000000000000000005534 156.0
HFD2_k127_2250172_6 Domain of unknown function DUF302 - - - 0.000000007412 60.0
HFD2_k127_2252044_0 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001128 259.0
HFD2_k127_2252044_1 permease - - - 0.0000000000000000000000000000000000000000000000000000000000000001747 236.0
HFD2_k127_2252714_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 608.0
HFD2_k127_2252714_1 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005958 407.0
HFD2_k127_2252714_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 371.0
HFD2_k127_2252714_3 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 301.0
HFD2_k127_2258332_0 ABC-type sugar transport system periplasmic component K10117 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 383.0
HFD2_k127_2258332_1 PFAM ROK family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009848 252.0
HFD2_k127_2261814_0 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 412.0
HFD2_k127_2265179_0 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000001125 254.0
HFD2_k127_2265179_1 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.00002808 57.0
HFD2_k127_226680_0 fructose 1,6-bisphosphate 1-phosphatase activity K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 448.0
HFD2_k127_2269587_0 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 458.0
HFD2_k127_2269587_1 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000002116 227.0
HFD2_k127_2269587_2 PFAM Glycosyl Hydrolase Family 88 K18581 - 3.2.1.180 0.000000000000000000000000000000000000000002002 160.0
HFD2_k127_2280065_0 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 460.0
HFD2_k127_2280065_1 PFAM Cytochrome bd ubiquinol oxidase, subunit I K00425 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 302.0
HFD2_k127_2280065_2 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 299.0
HFD2_k127_2280065_3 Short chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 300.0
HFD2_k127_2280065_4 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006765 282.0
HFD2_k127_2280065_5 MaoC domain protein dehydratase K00634,K17865 - 2.3.1.19,4.2.1.55 0.00000000000000000000000000000000000000000003278 164.0
HFD2_k127_2280065_6 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000001793 136.0
HFD2_k127_2280065_7 phospholipase Carboxylesterase K06999 - - 0.000000000000000008715 92.0
HFD2_k127_2280065_8 Domain of unknown function (DUF4281) - - - 0.00000000004131 70.0
HFD2_k127_2285202_0 Acetyl xylan esterase (AXE1) K01060 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005975,GO:0005976,GO:0006082,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009308,GO:0009987,GO:0010383,GO:0010410,GO:0016787,GO:0016788,GO:0016999,GO:0017144,GO:0019213,GO:0019752,GO:0030653,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043645,GO:0044036,GO:0044106,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0045491,GO:0046483,GO:0046555,GO:0046872,GO:0047739,GO:0052689,GO:0071554,GO:0071704,GO:0072338,GO:1901266,GO:1901360,GO:1901564 3.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 490.0
HFD2_k127_2285202_1 Two component transcriptional regulator, winged helix family K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003551 268.0
HFD2_k127_2285202_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000008109 261.0
HFD2_k127_2285202_3 homoserine kinase type II (protein kinase fold) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004703 265.0
HFD2_k127_2285202_4 -acetyltransferase - - - 0.0000000000000000000000000000000000000000004675 161.0
HFD2_k127_2285202_5 Diguanylate cyclase - - - 0.000004589 56.0
HFD2_k127_2291082_0 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED - - - 4.603e-201 650.0
HFD2_k127_2291082_1 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 548.0
HFD2_k127_2291082_2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K09065 - 2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 533.0
HFD2_k127_2291082_3 helix_turn _helix lactose operon repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007625 317.0
HFD2_k127_2291082_4 PFAM Dual specificity protein phosphatase - - - 0.0000000000002644 76.0
HFD2_k127_2297219_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 561.0
HFD2_k127_2297219_1 Belongs to the skp family K06142 - - 0.000000000000000000000000000000000000000000000000000005515 194.0
HFD2_k127_231210_0 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 2.942e-202 640.0
HFD2_k127_231210_1 Aldo/keto reductase family K00002 - 1.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 536.0
HFD2_k127_231210_10 Trypsin K04771 - 3.4.21.107 0.0002515 52.0
HFD2_k127_231210_2 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 498.0
HFD2_k127_231210_3 Periplasmic binding protein domain K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 462.0
HFD2_k127_231210_4 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 459.0
HFD2_k127_231210_5 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 428.0
HFD2_k127_231210_6 PFAM periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 336.0
HFD2_k127_231210_7 Alcohol dehydrogenase GroES-like domain K00094 - 1.1.1.251 0.000000000000000000000000000000000000000000000000000000000000000000000000000003017 274.0
HFD2_k127_231210_8 phosphinothricin N-acetyltransferase activity K03830 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000145 257.0
HFD2_k127_231210_9 nitric oxide dioxygenase activity K17247 - - 0.000000000000000000000008801 110.0
HFD2_k127_2314867_0 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 5.91e-221 691.0
HFD2_k127_2314867_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 550.0
HFD2_k127_2314867_2 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 505.0
HFD2_k127_2314867_3 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 487.0
HFD2_k127_2314867_4 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 394.0
HFD2_k127_2314867_5 Cytochrome c554 and c-prime - - - 0.00000000000000000009168 104.0
HFD2_k127_2314867_6 TM2 domain - - - 0.0000000000000000001077 93.0
HFD2_k127_2319773_0 cellulase activity K01183 - 3.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 317.0
HFD2_k127_2319773_1 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002865 276.0
HFD2_k127_2319773_2 COG3103 SH3 domain protein K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.0000005327 63.0
HFD2_k127_2328591_0 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000032 198.0
HFD2_k127_2328591_1 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000564 112.0
HFD2_k127_2328591_2 Sulfatase-modifying factor enzyme 1 K18912 - 1.14.99.50 0.0000000003247 72.0
HFD2_k127_233019_0 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms K00958 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 492.0
HFD2_k127_233019_1 Sulfate ABC transporter periplasmic sulfate-binding protein K02048 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 384.0
HFD2_k127_233019_2 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000005238 256.0
HFD2_k127_233019_3 Catalyzes the synthesis of activated sulfate K00860,K00955 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000001066 227.0
HFD2_k127_233019_4 (ABC) transporter K02047 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000008926 51.0
HFD2_k127_2332770_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 469.0
HFD2_k127_2332770_1 amino acid-binding ACT domain protein K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000008783 254.0
HFD2_k127_2332770_2 Major facilitator Superfamily - - - 0.000008651 58.0
HFD2_k127_2336949_0 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000003309 173.0
HFD2_k127_2336949_1 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000001558 166.0
HFD2_k127_2336949_2 NUDIX domain - - - 0.000000000000000000000000000000000000000000369 162.0
HFD2_k127_2336949_3 NUDIX domain - - - 0.00000000000000000000000000000000000000002287 157.0
HFD2_k127_2339288_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 612.0
HFD2_k127_2339288_1 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 308.0
HFD2_k127_2339288_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000001474 247.0
HFD2_k127_2339288_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000001125 226.0
HFD2_k127_2339288_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000007274 220.0
HFD2_k127_2339288_5 SMART GGDEF domain containing protein - - - 0.00000000000000000000000000002792 138.0
HFD2_k127_2339288_6 Periplasmic binding protein K01999 - - 0.0000006897 63.0
HFD2_k127_2339288_7 helix_turn _helix lactose operon repressor K02529 - - 0.0000007778 53.0
HFD2_k127_2339288_8 kDa ribonucleoprotein K11294 - - 0.0007563 44.0
HFD2_k127_2346194_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K18030 - 1.17.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 426.0
HFD2_k127_2346194_1 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 386.0
HFD2_k127_2346194_2 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 314.0
HFD2_k127_2346194_3 [2Fe-2S] binding domain K18029 - 1.17.2.1 0.0000000000000000000000000000000000000000000004018 183.0
HFD2_k127_2346194_4 DNA-binding transcription factor activity - - - 0.000000000000000000000000000001237 126.0
HFD2_k127_2346796_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000009829 192.0
HFD2_k127_2346796_1 - - - - 0.0000000000000000000000000000001434 136.0
HFD2_k127_2346796_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000001642 98.0
HFD2_k127_2347880_0 CHAT domain - - - 2.963e-275 876.0
HFD2_k127_2347880_1 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002139 284.0
HFD2_k127_2348474_0 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000001826 131.0
HFD2_k127_2348474_1 GYD domain - - - 0.000000000000000000000001819 106.0
HFD2_k127_2348474_2 Isochorismatase family K08281 - 3.5.1.19 0.000000005542 65.0
HFD2_k127_2353170_0 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K12528 - - 0.0 1086.0
HFD2_k127_2353170_1 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K01761 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 365.0
HFD2_k127_2353170_2 CHASE3 domain K02484,K07636,K07642,K07768,K11383,K18143 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564 2.7.13.3 0.00000000000000000000000000000000000000005108 170.0
HFD2_k127_2353170_3 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000001518 144.0
HFD2_k127_2364897_0 PFAM glycoside hydrolase family 29 (alpha-L-fucosidase) K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 312.0
HFD2_k127_2364897_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000000000000000000000000002311 150.0
HFD2_k127_236720_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009059 316.0
HFD2_k127_236720_1 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) K08680 - 4.2.99.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 294.0
HFD2_k127_236720_2 lipoprotein transporter activity K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001596 280.0
HFD2_k127_236720_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000972 138.0
HFD2_k127_236720_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000006892 128.0
HFD2_k127_236720_5 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily K01911 - 6.2.1.26 0.0000000000000000000253 93.0
HFD2_k127_236720_6 MacB-like periplasmic core domain K02004 - - 0.000000008913 62.0
HFD2_k127_2374189_0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008443 609.0
HFD2_k127_2374189_1 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008018 371.0
HFD2_k127_2374189_2 Catalyzes the dehydration of D-mannonate K01686 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 353.0
HFD2_k127_2374189_3 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000141 167.0
HFD2_k127_2374189_4 Ferritin-like - - - 0.000000000000000000000000000000000005176 144.0
HFD2_k127_2374189_5 intracellular signal transduction - - - 0.000000000000000000000000000000008153 148.0
HFD2_k127_2401898_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 506.0
HFD2_k127_2401898_1 alpha-L-arabinofuranosidase - - - 0.000000000000000000000000000000000004911 153.0
HFD2_k127_2404050_0 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000007116 220.0
HFD2_k127_2404050_1 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.000000000000000000000000001783 117.0
HFD2_k127_2409098_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K00162,K11381 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 609.0
HFD2_k127_2409098_1 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 599.0
HFD2_k127_2409098_2 PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 550.0
HFD2_k127_2409098_3 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 505.0
HFD2_k127_2409098_4 Enoyl-(Acyl carrier protein) reductase K00059,K00068 - 1.1.1.100,1.1.1.140 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008265 387.0
HFD2_k127_2409978_0 PFAM aminotransferase, class I and II K14155 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 465.0
HFD2_k127_2409978_1 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000002454 233.0
HFD2_k127_2409978_2 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000009479 215.0
HFD2_k127_2416019_0 COG1680 Beta-lactamase class C and other penicillin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001064 256.0
HFD2_k127_2416019_1 WD domain, G-beta repeat K12132 - 2.7.11.1 0.00000000006524 76.0
HFD2_k127_2416019_2 Cell Wall K01448 - 3.5.1.28 0.00001559 57.0
HFD2_k127_2416019_3 Rho guanine nucleotide exchange factor K20710 GO:0003674,GO:0005085,GO:0005088,GO:0005089,GO:0005488,GO:0005515,GO:0007154,GO:0007165,GO:0007264,GO:0008150,GO:0009987,GO:0017016,GO:0017048,GO:0019899,GO:0023052,GO:0031267,GO:0035556,GO:0043085,GO:0043087,GO:0043547,GO:0044093,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051020,GO:0051336,GO:0051345,GO:0051716,GO:0065007,GO:0065009,GO:0098772 - 0.000695 46.0
HFD2_k127_2426567_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000004141 211.0
HFD2_k127_2426567_1 Putative transposase of IS4/5 family (DUF4096) K07492 - - 0.00000000000000000000000000000000000001537 149.0
HFD2_k127_2426567_2 Winged helix-turn helix - - - 0.00000000000000000000000000000000000009644 149.0
HFD2_k127_2426567_3 Winged helix-turn helix - - - 0.0000000000000000001947 88.0
HFD2_k127_2426567_4 Transposase - - - 0.000000000000742 72.0
HFD2_k127_2434939_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000002881 250.0
HFD2_k127_2434939_1 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000002775 178.0
HFD2_k127_2434939_2 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000003418 141.0
HFD2_k127_2434939_3 Transglycosylase SLT domain K08309 - - 0.0000000002794 70.0
HFD2_k127_2434939_4 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.00003284 48.0
HFD2_k127_2438290_0 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000001123 113.0
HFD2_k127_2438290_1 PFAM diacylglycerol kinase K00901 - 2.7.1.107 0.000000000000000000000007154 110.0
HFD2_k127_2438290_2 Polysaccharide biosynthesis protein - - - 0.00000000004388 75.0
HFD2_k127_2439837_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 369.0
HFD2_k127_2439837_1 PFAM Methionine sulfoxide reductase B K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000002245 191.0
HFD2_k127_2439837_2 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000001188 157.0
HFD2_k127_2439837_3 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000003424 136.0
HFD2_k127_2439837_4 Peptidase family M50 - - - 0.00004539 53.0
HFD2_k127_2450488_0 helix_turn_helix, Lux Regulon K03556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008779 478.0
HFD2_k127_2450488_1 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000001307 232.0
HFD2_k127_2450488_2 serine threonine protein kinase K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.000000000000000000000000000000000000000000000000003364 209.0
HFD2_k127_2450488_3 Acyl-transferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000001693 184.0
HFD2_k127_2450488_4 Ferritin-like domain K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000003296 172.0
HFD2_k127_2450488_5 - - - - 0.000000000000003122 78.0
HFD2_k127_2450488_6 Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin K13282 - 3.4.15.6 0.0000000007646 68.0
HFD2_k127_2450488_7 - - - - 0.000000001379 60.0
HFD2_k127_2450488_8 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00004775 55.0
HFD2_k127_2450488_9 PFAM FHA domain - - - 0.0004585 44.0
HFD2_k127_2451267_0 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 446.0
HFD2_k127_2451267_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 348.0
HFD2_k127_2451267_10 Phosphonate ABC transporter K02044 - - 0.000000000007511 76.0
HFD2_k127_2451267_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 313.0
HFD2_k127_2451267_3 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 309.0
HFD2_k127_2451267_4 ABC transporter K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 297.0
HFD2_k127_2451267_5 PFAM LmbE family protein K18455 - 3.5.1.115 0.000000000000000000000000000000000000000000000000000000000000000001139 238.0
HFD2_k127_2451267_6 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000000000000000000000000000000000000000000000008185 225.0
HFD2_k127_2451267_7 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.000000000000000000000000000000000000000000002986 181.0
HFD2_k127_2451267_8 PFAM Endonuclease Exonuclease phosphatase - - - 0.00000000000000000000000000000007296 138.0
HFD2_k127_2451267_9 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000001808 104.0
HFD2_k127_2452857_0 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002371 255.0
HFD2_k127_2452857_1 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000001402 162.0
HFD2_k127_2452857_2 protein serine/threonine phosphatase activity - - - 0.0000000000000000000000000000000004991 146.0
HFD2_k127_245441_0 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000001736 233.0
HFD2_k127_245441_1 chitinase K01183 - 3.2.1.14 0.000000000000000000000000000000003913 140.0
HFD2_k127_2468994_0 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006139,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009108,GO:0009117,GO:0009165,GO:0009308,GO:0009310,GO:0009435,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019441,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0020037,GO:0022607,GO:0034641,GO:0034654,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0046906,GO:0048037,GO:0051186,GO:0051188,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.13.11.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 405.0
HFD2_k127_2468994_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 399.0
HFD2_k127_2468994_2 PFAM Glycosyl hydrolases family 16 - - - 0.00000000000000000000000000000000001254 142.0
HFD2_k127_2468994_3 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000001626 133.0
HFD2_k127_2468994_4 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.000000000000000000000001372 105.0
HFD2_k127_2468994_5 Electron transfer DM13 - - - 0.00000000000008789 79.0
HFD2_k127_2468994_6 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000003074 84.0
HFD2_k127_2468994_7 Bacterial extracellular solute-binding protein K02027 - - 0.000000004848 70.0
HFD2_k127_2469335_0 WD domain, G-beta repeat - - - 9.855e-199 668.0
HFD2_k127_2469335_1 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000407 246.0
HFD2_k127_2469335_2 ATP-dependent transcriptional regulator K03556 - - 0.000000000001633 82.0
HFD2_k127_2475621_0 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 552.0
HFD2_k127_2475621_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 401.0
HFD2_k127_2475621_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000001227 104.0
HFD2_k127_248152_0 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 372.0
HFD2_k127_248152_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000002599 169.0
HFD2_k127_2485791_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 6.84e-278 878.0
HFD2_k127_2485791_1 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 565.0
HFD2_k127_2485791_2 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 300.0
HFD2_k127_2485791_3 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000007063 248.0
HFD2_k127_2485791_4 Amidohydrolase family - - - 0.00000000000000000000000000009454 117.0
HFD2_k127_249295_0 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 378.0
HFD2_k127_249295_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007525 273.0
HFD2_k127_249295_2 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000000000000000000007494 228.0
HFD2_k127_249295_3 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - 0.000000000000000000000000000000000000000000004377 179.0
HFD2_k127_249295_4 Cytidylyltransferase-like - - - 0.0000000000000000000000000000000000000000006132 161.0
HFD2_k127_2495516_0 Aldehyde dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 558.0
HFD2_k127_2495516_1 Type III restriction enzyme res subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001648 275.0
HFD2_k127_2495516_2 Catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000009362 206.0
HFD2_k127_2495516_3 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000001447 103.0
HFD2_k127_2495516_4 - - - - 0.0000004166 57.0
HFD2_k127_2501919_0 Molydopterin dinucleotide binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 577.0
HFD2_k127_2501919_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 494.0
HFD2_k127_2501919_2 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 353.0
HFD2_k127_2501919_3 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000002422 161.0
HFD2_k127_2501919_4 - - - - 0.00002848 49.0
HFD2_k127_2506482_0 Catalyzes the NADPH-dependent reduction of LysW - aminoadipate 6-phosphate to yield LysW -aminoadipate 6- semialdehyde K05829 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 461.0
HFD2_k127_2506482_1 Belongs to the RimK family K05827 - 6.3.2.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 378.0
HFD2_k127_2506482_2 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000003958 107.0
HFD2_k127_2506482_3 - K05826 - - 0.0000000000000000001947 88.0
HFD2_k127_2508990_0 Peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 384.0
HFD2_k127_2508990_1 CHAT domain - - - 0.00000008262 66.0
HFD2_k127_2510486_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 412.0
HFD2_k127_2510486_1 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000004106 201.0
HFD2_k127_2510486_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.0000001089 62.0
HFD2_k127_2510486_3 - - - - 0.0000108 56.0
HFD2_k127_2524310_0 Heavy metal transport detoxification protein K17686 - 3.6.3.54 2.185e-235 753.0
HFD2_k127_2524310_1 ABC transporter substrate-binding protein PnrA-like K02058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 398.0
HFD2_k127_2524310_2 PFAM basic membrane lipoprotein K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007831 385.0
HFD2_k127_2524310_3 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000004348 249.0
HFD2_k127_2524310_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000105 145.0
HFD2_k127_2524310_5 Metal-sensitive transcriptional repressor K21600 - - 0.0000000000000000000000000001977 117.0
HFD2_k127_2524310_6 Heavy-metal-associated domain - - - 0.000000000000000005576 85.0
HFD2_k127_2546873_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000001856 213.0
HFD2_k127_2546873_1 Transcriptional regulatory protein, C terminal K07658 - - 0.000000000000000000000000000000000009123 138.0
HFD2_k127_2564684_0 PFAM cytoplasmic peptidoglycan synthetase domain protein K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000004467 268.0
HFD2_k127_2564684_1 Bacterial SH3 domain homologues - - - 0.0001607 54.0
HFD2_k127_2576460_0 HMGL-like - - - 2.924e-223 699.0
HFD2_k127_2576460_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 483.0
HFD2_k127_2576460_2 Dehydrogenase E1 component K00164,K01616 GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 400.0
HFD2_k127_2576460_3 Helix-turn-helix domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 382.0
HFD2_k127_2576460_4 protein conserved in bacteria containing thioredoxin-like domain - - - 0.0000000000000000000000000000000000000000000000001108 188.0
HFD2_k127_2576460_5 4-vinyl reductase, 4VR - - - 0.00000000000000000000000000000000000000000000009902 177.0
HFD2_k127_2576460_6 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.000000000000000000000000000000000186 152.0
HFD2_k127_2576460_7 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.00000000000659 67.0
HFD2_k127_2577752_0 L-phenylalanine transmembrane transporter activity K01997,K01998 - - 2.097e-273 852.0
HFD2_k127_2577752_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004813 531.0
HFD2_k127_2577752_2 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 378.0
HFD2_k127_2577752_3 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 348.0
HFD2_k127_2577778_0 Putative esterase - - - 0.00000000000000000000000000000000000000000000001149 180.0
HFD2_k127_2594309_0 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000005336 187.0
HFD2_k127_2594309_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000000000000000000000000000007259 182.0
HFD2_k127_2594309_2 Belongs to the BI1 family K06890 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000001535 138.0
HFD2_k127_2594309_3 Glyoxalase-like domain - - - 0.0000000000000000000000000000002145 134.0
HFD2_k127_2598899_0 transposase activity K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 347.0
HFD2_k127_2598899_1 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986 - 2.7.7.49 0.000000000000000004974 84.0
HFD2_k127_2600313_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 561.0
HFD2_k127_2600313_1 protein histidine kinase activity K02484,K07636,K07642 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006969 312.0
HFD2_k127_2600313_2 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 300.0
HFD2_k127_2600313_3 Domain of unknown function (DUF4432) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002989 278.0
HFD2_k127_2600313_4 calcium- and calmodulin-responsive adenylate cyclase activity K20276 - - 0.000000000000000000000000000000000000000000000000000000003535 218.0
HFD2_k127_2600313_5 SnoaL-like polyketide cyclase K06893 - - 0.0000000000000000000000001109 113.0
HFD2_k127_2600313_6 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.000000000000000000005453 95.0
HFD2_k127_2604885_0 Transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 436.0
HFD2_k127_2604885_1 reverse transcriptase K00986 - 2.7.7.49 0.00000000000000000008562 90.0
HFD2_k127_2604885_2 transposase IS891 IS1136 IS1341 family K07496 - - 0.0000000000000000136 84.0
HFD2_k127_2604885_3 - - - - 0.0000001093 63.0
HFD2_k127_2604885_4 antibiotic catabolic process - - - 0.000005549 58.0
HFD2_k127_2604885_5 PFAM IS1 transposase K07480 - - 0.00001043 49.0
HFD2_k127_2604885_6 Right handed beta helix region - - - 0.00004552 50.0
HFD2_k127_2604885_7 Lysin motif - - - 0.00005264 55.0
HFD2_k127_2617371_0 - - - - 0.0 1035.0
HFD2_k127_2617371_1 His Kinase A (phospho-acceptor) domain - - - 0.00000000000000000000000000000000000000000000000003664 190.0
HFD2_k127_2617371_2 Subtilase family K17734 - - 0.0000008265 59.0
HFD2_k127_2627355_0 Beta-lactamase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000858 211.0
HFD2_k127_262829_0 transposition, DNA-mediated K02529,K20971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 354.0
HFD2_k127_262829_1 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007968 254.0
HFD2_k127_262829_2 S-acyltransferase activity K00627,K03310,K03578,K12132 - 2.3.1.12,2.7.11.1,3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000133 231.0
HFD2_k127_262829_3 SIS domain - - - 0.0000000000000000000000000000000000000000000000000000000000004071 221.0
HFD2_k127_262829_4 creatininase K01470 - 3.5.2.10 0.000000000000000000000000000002458 123.0
HFD2_k127_2633743_0 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009136 257.0
HFD2_k127_2633743_1 Bacterial membrane protein YfhO - - - 0.00000000000000000000000000000000000000000000003529 194.0
HFD2_k127_2633743_2 - - - - 0.0000006255 53.0
HFD2_k127_2635013_0 Amidohydrolase family K18456 - 3.5.4.32 3.325e-210 662.0
HFD2_k127_2635013_1 cyclic 2,3-diphosphoglycerate synthetase activity - - - 6.308e-209 656.0
HFD2_k127_2635013_10 - - - - 0.000000000000000002619 100.0
HFD2_k127_2635013_11 domain in sensory proteins (DUF2308) - - - 0.0000000002227 70.0
HFD2_k127_2635013_2 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 369.0
HFD2_k127_2635013_3 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000000000000000000000000002486 237.0
HFD2_k127_2635013_4 pyridoxamine 5'-phosphate K07005 - - 0.00000000000000000000000000000000000000000000000000000000000135 216.0
HFD2_k127_2635013_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000007578 186.0
HFD2_k127_2635013_6 - - - - 0.000000000000000000000000000000000000000000000009152 178.0
HFD2_k127_2635013_7 Putative cyclase - - - 0.000000000000000000000000000000000000000001445 164.0
HFD2_k127_2635013_8 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.0000000000000000000000005653 116.0
HFD2_k127_2635013_9 Protein of unknown function (DUF4230) - - - 0.0000000000000000005858 96.0
HFD2_k127_2639070_0 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 316.0
HFD2_k127_2639070_1 Hypothetical methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004293 249.0
HFD2_k127_2639070_2 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.0000000000000000000009899 103.0
HFD2_k127_2639070_5 LysM domain - - - 0.000001221 61.0
HFD2_k127_264184_0 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007759 516.0
HFD2_k127_264184_1 Transposase is116 is110 is902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 349.0
HFD2_k127_264184_2 transposition, DNA-mediated K02529,K20971 - - 0.000000000000000000003563 100.0
HFD2_k127_264184_3 transposition K07497 - - 0.00000000000000000003431 102.0
HFD2_k127_264184_4 YceI-like domain - - - 0.0000000000005539 77.0
HFD2_k127_264184_5 PFAM peptidase U32 K08303 - - 0.00000005186 58.0
HFD2_k127_264237_0 Argininosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009448 499.0
HFD2_k127_264237_1 TIGRFAM acetylornithine and succinylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 412.0
HFD2_k127_264237_2 NUDIX domain K08312 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019144,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872 - 0.00000000000008932 81.0
HFD2_k127_264237_3 ArgJ family K00620,K00930 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35,2.7.2.8 0.00003666 47.0
HFD2_k127_2647326_0 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001791 268.0
HFD2_k127_2647326_1 helix_turn _helix lactose operon repressor K02529 - - 0.0000000000000000000000000000000000001115 156.0
HFD2_k127_2647326_2 Domain of unknown function (DUF1905) - - - 0.000000000000000000000000000000000002585 142.0
HFD2_k127_2647326_3 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000002247 125.0
HFD2_k127_2647326_4 RibD C-terminal domain - - - 0.0000000000001938 73.0
HFD2_k127_264801_0 sh3 domain protein K01448,K04771 - 3.4.21.107,3.5.1.28 0.000000005303 68.0
HFD2_k127_2648778_0 Binding-protein-dependent transport system inner membrane component K10189 - - 0.00000000000000000000000000000000000000000000000000000173 199.0
HFD2_k127_2648778_1 Extracellular solute-binding protein K02027 - - 0.0000000324 64.0
HFD2_k127_2650555_0 Fe-S oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 498.0
HFD2_k127_2650555_1 4Fe-4S dicluster domain K00125,K03646 - 1.17.1.9 0.000000000000000000000000000003238 132.0
HFD2_k127_2650555_2 Rieske 2Fe-2S - - - 0.00000000000000000000009957 103.0
HFD2_k127_2650555_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.00000000002801 67.0
HFD2_k127_2651836_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 490.0
HFD2_k127_2651836_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006847 465.0
HFD2_k127_2651836_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 422.0
HFD2_k127_2651836_3 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 411.0
HFD2_k127_2651836_4 AsnC-type helix-turn-helix domain K05710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006901 340.0
HFD2_k127_2651836_5 Uroporphyrinogen-III synthase HemD K01719,K13542 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000003238 221.0
HFD2_k127_2652097_0 sigma factor antagonist activity K04757 - 2.7.11.1 0.00000000000000000000000000000239 125.0
HFD2_k127_2652097_1 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000001658 116.0
HFD2_k127_2652097_2 Sigma-70 region 2 - - - 0.000000000002096 78.0
HFD2_k127_2652097_3 STAS domain K06378 - - 0.000000001831 66.0
HFD2_k127_2652261_0 Hydrogenase expression formation protein (HypE) K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 316.0
HFD2_k127_2652261_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 299.0
HFD2_k127_2652261_2 ABC transporter, transmembrane region K06147,K18890 - - 0.000000000000000000000000000000000000000000000000000003083 193.0
HFD2_k127_2652261_3 Polysaccharide deacetylase - - - 0.000000000000001853 86.0
HFD2_k127_2659767_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 550.0
HFD2_k127_2659767_1 WD40 repeat, subgroup - - - 0.00000000000000000000000000000000000000000000000000000000002093 232.0
HFD2_k127_2659767_2 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000002366 170.0
HFD2_k127_2659767_3 Major Facilitator Superfamily - - - 0.000000000002113 72.0
HFD2_k127_2663917_0 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 446.0
HFD2_k127_2663917_1 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 0.00000000000000000000000000000000000000000000000000000000000000008369 228.0
HFD2_k127_2664626_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 315.0
HFD2_k127_2664626_1 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006671 247.0
HFD2_k127_2667897_0 DEAD H associated K03724 - - 0.00000000000000000000000000000000000000000000000000000000000001388 239.0
HFD2_k127_2667897_1 Zinc finger, SWIM domain protein - - - 0.000000000000000000000000000000000000000000000000000000001958 221.0
HFD2_k127_2667897_2 helicase superfamily c-terminal domain K03654 - 3.6.4.12 0.0000000000002219 72.0
HFD2_k127_2673156_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 4.086e-257 803.0
HFD2_k127_2673156_1 Selenocysteine-specific translation elongation factor K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 574.0
HFD2_k127_2673156_2 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002687 260.0
HFD2_k127_2673156_3 Glycosyl transferases group 1 - - - 0.0001691 51.0
HFD2_k127_2675718_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 289.0
HFD2_k127_2675718_1 energy transducer activity K03531,K03832 - - 0.00000000000000000000000000000000000009681 162.0
HFD2_k127_2681787_0 PFAM transposase Tn3 family protein - - - 0.0 1124.0
HFD2_k127_2681787_1 integrase family - - - 0.0000000000000000000000000000003496 129.0
HFD2_k127_2685515_0 ATP hydrolysis coupled proton transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 357.0
HFD2_k127_2685515_3 Acetyltransferase (GNAT) family - - - 0.000000001428 59.0
HFD2_k127_2687608_0 PFAM Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 445.0
HFD2_k127_2687608_1 PFAM Insertion element protein - - - 0.00000000000000000000000002169 111.0
HFD2_k127_2699132_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000003834 260.0
HFD2_k127_2699132_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000002844 224.0
HFD2_k127_2699132_2 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000004063 176.0
HFD2_k127_2699132_3 UPF0060 membrane protein K09771 - - 0.0000000000000000000000000000000004247 134.0
HFD2_k127_2706345_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 4.37e-321 997.0
HFD2_k127_2706345_1 PFAM ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 520.0
HFD2_k127_2706345_2 NAD synthase K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 348.0
HFD2_k127_2706345_3 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 314.0
HFD2_k127_2706345_4 transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003375 264.0
HFD2_k127_2706345_5 PFAM GCN5-related N-acetyltransferase K03825 - - 0.00000000000000000000000000000000000000000000000000396 186.0
HFD2_k127_2706345_6 response to heat K07090 - - 0.000000000000000000000000000004627 129.0
HFD2_k127_2706345_7 Transcriptional regulator - - - 0.000005466 49.0
HFD2_k127_2709978_0 DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 1.336e-227 715.0
HFD2_k127_2709978_1 alpha-glucuronidase activity K01235 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010383,GO:0010410,GO:0010413,GO:0016052,GO:0016787,GO:0016798,GO:0033939,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044260,GO:0045491,GO:0045493,GO:0071554,GO:0071704,GO:1901575,GO:2000886 3.2.1.139 9.564e-221 692.0
HFD2_k127_2709978_2 Aldo/keto reductase family K19265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 515.0
HFD2_k127_2709978_3 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 430.0
HFD2_k127_2709978_4 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000009818 232.0
HFD2_k127_2709978_5 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000005778 222.0
HFD2_k127_2709978_6 - K11477 - - 0.0000000000000000116 84.0
HFD2_k127_2709978_7 Acetamidase/Formamidase family - - - 0.0000000002719 68.0
HFD2_k127_2709978_8 WD40-like Beta Propeller Repeat K03641 - - 0.000009931 57.0
HFD2_k127_2716184_0 PFAM Bacterial regulatory proteins, lacI family K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 293.0
HFD2_k127_2716184_1 ABC transporter, substratebinding protein K10232 - - 0.000000000000000000000000000000000000000000000000000000000000000000122 247.0
HFD2_k127_2716184_2 von Willebrand factor type A domain K07114 - - 0.00000000000000000000000002618 126.0
HFD2_k127_2716184_3 Trehalose utilisation - - - 0.000000000000001885 76.0
HFD2_k127_2717403_0 bifunctional purine biosynthetic protein K11788 GO:0003674,GO:0003824,GO:0004637,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009112,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564 6.3.3.1,6.3.4.13 1.639e-213 687.0
HFD2_k127_2717403_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 500.0
HFD2_k127_2717403_2 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 362.0
HFD2_k127_2717403_3 Protein of unknown function (DUF2568) - - - 0.00000000000000000000000000005805 121.0
HFD2_k127_2720434_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005947 364.0
HFD2_k127_2720434_1 ROK family K00886 - 2.7.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 308.0
HFD2_k127_2720434_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001082 283.0
HFD2_k127_2720434_3 Response regulator, receiver K11443 - - 0.000000000000003859 80.0
HFD2_k127_2720434_4 Histidine kinase - - - 0.0000000000001704 74.0
HFD2_k127_272239_0 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001882 266.0
HFD2_k127_272239_1 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000002856 162.0
HFD2_k127_272239_2 PFAM CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000009693 163.0
HFD2_k127_272239_3 Chitinase class I K03791 - - 0.000000000000000000000007733 116.0
HFD2_k127_272239_4 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000007021 96.0
HFD2_k127_272239_5 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.00000000005044 64.0
HFD2_k127_2730856_0 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 533.0
HFD2_k127_2730856_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 440.0
HFD2_k127_2730856_2 SMART AAA ATPase K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 405.0
HFD2_k127_2730856_3 Zinc finger domain - - - 0.00000000000000000000000000000000000000000000000009519 195.0
HFD2_k127_2730856_4 Isochorismatase family - - - 0.00000000000000000000000000000000000000003026 162.0
HFD2_k127_2730856_5 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000004909 100.0
HFD2_k127_2730856_6 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000271 89.0
HFD2_k127_2730856_7 POTRA domain, FtsQ-type K01921,K03589 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.00000000001299 76.0
HFD2_k127_2730856_8 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms K07027 - - 0.000000001268 64.0
HFD2_k127_2741362_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 311.0
HFD2_k127_2741362_1 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000004072 236.0
HFD2_k127_2741362_2 Branched-chain amino acid transport K01996 GO:0000166,GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005488,GO:0005524,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008144,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0097159,GO:0097367,GO:0098655,GO:0098656,GO:1901265,GO:1901363,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000008524 202.0
HFD2_k127_2741362_3 PFAM inner-membrane translocator K01997 - - 0.000000000000000000000000000000000000003584 158.0
HFD2_k127_2741362_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000005524 149.0
HFD2_k127_2741362_5 PFAM inner-membrane translocator K01998 - - 0.0000000000000000000000004739 109.0
HFD2_k127_2741362_6 PFAM inner-membrane translocator K01998 - - 0.000000000000000001601 93.0
HFD2_k127_2741362_7 Periplasmic binding protein domain K01999 - - 0.0000133 54.0
HFD2_k127_2774624_0 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 516.0
HFD2_k127_2774624_1 transposase activity - - - 0.0000000000000000003199 90.0
HFD2_k127_2774624_2 transposase activity - - - 0.00000000000001519 80.0
HFD2_k127_2774624_3 zinc-finger binding domain of transposase IS66 K07484 - - 0.000000000005943 71.0
HFD2_k127_2774624_4 transposase activity - - - 0.00002609 49.0
HFD2_k127_2786784_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 597.0
HFD2_k127_2786784_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000001039 154.0
HFD2_k127_2809470_0 permease - - - 0.00000000000000000000000000000000000000000000000000000000000000001345 237.0
HFD2_k127_2809470_1 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000007308 239.0
HFD2_k127_2809470_2 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000005009 139.0
HFD2_k127_2809470_3 PFAM Transglycosylase-associated protein - - - 0.000000000006638 69.0
HFD2_k127_2809470_4 sh3 domain protein K01448,K04771 - 3.4.21.107,3.5.1.28 0.000001019 62.0
HFD2_k127_2810364_0 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006199 600.0
HFD2_k127_2810364_1 PFAM Translin K07477 - - 0.000000000000000000000000000000000000000000000000000000000002377 218.0
HFD2_k127_2810364_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000002482 137.0
HFD2_k127_2814929_0 Cytidylyltransferase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 476.0
HFD2_k127_2814929_1 - - - - 0.0000000000003006 76.0
HFD2_k127_2814929_3 glyoxalase III activity - - - 0.00007272 55.0
HFD2_k127_2815300_0 Thiamine pyrophosphate enzyme, central domain K00158,K01576,K01652 - 1.2.3.3,2.2.1.6,4.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 546.0
HFD2_k127_2815300_1 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 295.0
HFD2_k127_2815300_2 PFAM Creatininase K01470 - 3.5.2.10 0.00000000003266 66.0
HFD2_k127_2831773_0 - K07138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 504.0
HFD2_k127_2831773_1 Iron-containing alcohol dehydrogenase K00001,K01714,K13954 - 1.1.1.1,4.3.3.7 0.000000000000000000000000000000000000000000000000417 181.0
HFD2_k127_2831773_2 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000002419 113.0
HFD2_k127_2839893_0 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 325.0
HFD2_k127_2839893_1 COG1335 Amidases related to nicotinamidase - - - 0.00000000000000000000000000000000000000000000000000000000000001235 220.0
HFD2_k127_2839893_2 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000002352 104.0
HFD2_k127_2839893_3 Cell wall-associated hydrolase (invasion-associated protein) - - - 0.00000000000000541 85.0
HFD2_k127_2839893_4 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000001597 68.0
HFD2_k127_2839893_5 - - - - 0.00000002555 59.0
HFD2_k127_2840052_0 cell adhesion involved in biofilm formation K20276 - - 0.0000000000000000000000000000000000005025 150.0
HFD2_k127_2840052_1 domain, Protein - - - 0.0003143 54.0
HFD2_k127_2842359_0 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 524.0
HFD2_k127_2842359_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 447.0
HFD2_k127_2842359_10 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000002248 153.0
HFD2_k127_2842359_11 Histidine kinase K19694 - - 0.000000000000000000006394 100.0
HFD2_k127_2842359_12 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000001205 104.0
HFD2_k127_2842359_14 Transcriptional regulator - - - 0.000002022 59.0
HFD2_k127_2842359_15 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000003917 58.0
HFD2_k127_2842359_2 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 349.0
HFD2_k127_2842359_3 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 334.0
HFD2_k127_2842359_4 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000008888 252.0
HFD2_k127_2842359_5 UbiA prenyltransferase family K02548 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046428,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000001355 230.0
HFD2_k127_2842359_6 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000003862 222.0
HFD2_k127_2842359_7 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000001631 208.0
HFD2_k127_2842359_8 4-amino-4-deoxy-L-arabinose transferase activity K16648 - - 0.000000000000000000000000000000000000000000000138 188.0
HFD2_k127_2842359_9 PFAM Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000003312 147.0
HFD2_k127_2848969_0 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 346.0
HFD2_k127_2848969_1 PFAM O-antigen polymerase - - - 0.000000000000000000000000000000000000000000000000000000000001159 224.0
HFD2_k127_2848969_2 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000000000000000000000000002176 195.0
HFD2_k127_2848969_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000004635 65.0
HFD2_k127_2848969_4 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.00002901 56.0
HFD2_k127_2862519_0 virulence plasmid 65kDa B protein - - - 0.0 1127.0
HFD2_k127_2872352_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 469.0
HFD2_k127_2872352_1 Adenosine/AMP deaminase K01488,K18286,K21053 GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.4.2,3.5.4.4,3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 379.0
HFD2_k127_2872352_2 Periplasmic binding protein domain K02058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 325.0
HFD2_k127_2872352_3 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 304.0
HFD2_k127_2872352_4 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 309.0
HFD2_k127_2877888_0 carbohydrate transport K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 469.0
HFD2_k127_2877888_1 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 365.0
HFD2_k127_2877888_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 334.0
HFD2_k127_2877888_3 Transcriptional regulator K05784,K21727 - - 0.0000000000000000000000000000000000000000000000008034 181.0
HFD2_k127_2877888_4 ABC-type sugar transport system periplasmic component K10439 - - 0.0000000000000000005264 89.0
HFD2_k127_2886422_0 OmpA family - - - 0.0 2533.0
HFD2_k127_2886422_1 Domain of unknown function DUF11 - - - 1.371e-276 922.0
HFD2_k127_2886422_2 - - - - 0.00000000000000000000000000000000000000000000000000000000003608 209.0
HFD2_k127_2889609_0 Alpha galactosidase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007131 480.0
HFD2_k127_2889609_1 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000001476 269.0
HFD2_k127_2889609_2 Bacterial extracellular solute-binding protein K05813 - - 0.000000000000287 75.0
HFD2_k127_289322_0 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 1.803e-285 884.0
HFD2_k127_289322_1 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 539.0
HFD2_k127_289322_2 PFAM LmbE family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 344.0
HFD2_k127_289322_3 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000004838 203.0
HFD2_k127_289322_4 Carbamoyl-phosphate synthetase large chain domain protein K01968 - 6.4.1.4 0.0000000000000000000008495 96.0
HFD2_k127_289909_0 transposition - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 490.0
HFD2_k127_289909_1 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 378.0
HFD2_k127_289909_2 response to heat K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 310.0
HFD2_k127_289909_3 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000005372 169.0
HFD2_k127_289909_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000001667 130.0
HFD2_k127_289909_5 COG0607 Rhodanese-related sulfurtransferase - - - 0.0000000000000000000006194 97.0
HFD2_k127_289909_6 Regulatory protein, FmdB family - - - 0.000000004419 62.0
HFD2_k127_2903507_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002437 271.0
HFD2_k127_2903507_1 Protein of unknown function (DUF3048) C-terminal domain - - - 0.000000000000000000000000000000000000000002987 169.0
HFD2_k127_2903507_2 Lysin motif - - - 0.0000000000000000005855 100.0
HFD2_k127_2903507_3 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000002402 95.0
HFD2_k127_2903507_4 Male sterility protein K00091,K19997 - 1.1.1.219,5.1.3.26 0.00003852 47.0
HFD2_k127_2918479_0 Protein of unknown function (DUF3604) - - - 2.07e-279 869.0
HFD2_k127_2918479_1 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 340.0
HFD2_k127_2918479_2 PPIC-type PPIASE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001404 237.0
HFD2_k127_2918479_3 HupE / UreJ protein K03192 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000001223 231.0
HFD2_k127_2918479_4 HupE / UreJ protein - - - 0.000000000000000000000000000000000001471 149.0
HFD2_k127_2922841_0 PFAM peptidase M4 thermolysin K08603 - 3.4.24.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 469.0
HFD2_k127_2922841_1 - - - - 0.0000000000000000000002196 99.0
HFD2_k127_2922841_2 Pyrophosphatase K06019 - 3.6.1.1 0.0000000000000001829 83.0
HFD2_k127_2922841_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000002581 81.0
HFD2_k127_2922841_4 import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.000006978 48.0
HFD2_k127_292431_0 Elongator protein 3, MiaB family, Radical SAM - - - 3.089e-258 811.0
HFD2_k127_292431_1 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000554 166.0
HFD2_k127_2935182_0 helix_turn_helix, Lux Regulon K03556 - - 4.145e-257 816.0
HFD2_k127_2935182_1 transposition K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 394.0
HFD2_k127_2935182_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007589 244.0
HFD2_k127_2935182_3 - - - - 0.0000000000000000000477 95.0
HFD2_k127_2937179_0 zinc-finger binding domain of transposase IS66 K07484 - - 0.0000000000000000000000000000000000000000000000000000000002037 216.0
HFD2_k127_2937179_1 Glycogen debranching enzyme - - - 0.0000000000000000000000000000000000000002387 167.0
HFD2_k127_2937179_2 Transposase IS66 family K07484 - - 0.0000000000000000000000004706 110.0
HFD2_k127_2937547_0 chitin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 361.0
HFD2_k127_2937547_1 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 337.0
HFD2_k127_2937547_2 aldo keto reductase - - - 0.0000000000000000000000000000000000000000002954 164.0
HFD2_k127_2937633_0 Mannosyl oligosaccharide glucosidase - - - 0.0 1230.0
HFD2_k127_2937633_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000275 269.0
HFD2_k127_2937633_2 Transmembrane secretion effector - - - 0.00000001374 62.0
HFD2_k127_2940160_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 475.0
HFD2_k127_2940160_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 387.0
HFD2_k127_2940160_2 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000005126 203.0
HFD2_k127_2940160_3 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000005856 114.0
HFD2_k127_2940160_4 intracellular signal transduction - - - 0.00000003395 66.0
HFD2_k127_2940160_5 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.00002144 51.0
HFD2_k127_2941012_0 Serine carboxypeptidase - - - 4.804e-205 648.0
HFD2_k127_2941012_1 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.0000000000000000000000000000000000000000000001844 194.0
HFD2_k127_2941012_2 Ig-like domain from next to BRCA1 gene - - - 0.00000000000000000000000000000000000000003553 177.0
HFD2_k127_2949338_0 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 297.0
HFD2_k127_2949338_1 Methyltransferase type 11 K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004917 280.0
HFD2_k127_2949338_2 Methyltransferase type 11 - - - 0.00000000000000000000000000000008818 129.0
HFD2_k127_2953671_0 Peptidase C39 family K06147 - - 1.944e-258 824.0
HFD2_k127_2953671_1 ABC transporter, ATP-binding protein K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 359.0
HFD2_k127_2956853_0 carbohydrate transport K02027 - - 0.0000000000000000000000000000000000000000000000000000000000002053 226.0
HFD2_k127_2956853_1 PFAM Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000008972 173.0
HFD2_k127_2956853_2 PFAM transferase hexapeptide repeat containing protein K16881 - 2.7.7.13,5.4.2.8 0.000000006584 59.0
HFD2_k127_2960794_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352,K21307 - 1.8.5.5,1.8.5.6 2.088e-244 774.0
HFD2_k127_2960794_1 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 334.0
HFD2_k127_2960794_2 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000001117 156.0
HFD2_k127_2960794_3 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000000001449 153.0
HFD2_k127_2960794_4 Sulphur transport K07112 - - 0.000000000000000000000000000000000008426 145.0
HFD2_k127_2960794_5 - - - - 0.000000000000000000000003524 113.0
HFD2_k127_2961442_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 1.236e-227 715.0
HFD2_k127_2961442_1 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000006979 175.0
HFD2_k127_2974113_0 Belongs to the SEDS family - - - 1.271e-209 679.0
HFD2_k127_2974113_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 402.0
HFD2_k127_2974113_2 Iron/manganese superoxide dismutases, alpha-hairpin domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000001269 226.0
HFD2_k127_2974113_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000001081 187.0
HFD2_k127_2974113_4 FHA domain - - - 0.0003881 44.0
HFD2_k127_2980262_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 1.698e-254 811.0
HFD2_k127_2980262_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 433.0
HFD2_k127_2980262_2 PFAM Aminotransferase class I and II K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 388.0
HFD2_k127_2994833_0 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 363.0
HFD2_k127_2995587_0 PFAM transcriptional regulator TrmB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005522 269.0
HFD2_k127_2995587_1 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000241 254.0
HFD2_k127_2995587_2 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000001096 230.0
HFD2_k127_2995587_3 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000001418 183.0
HFD2_k127_2995587_4 methyltransferase activity - - - 0.00000000000000000000000000000004862 133.0
HFD2_k127_2997310_0 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000004194 106.0
HFD2_k127_2997310_1 GAF domain - - - 0.000000000000000001611 99.0
HFD2_k127_3000651_0 ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 293.0
HFD2_k127_3000651_1 Two component transcriptional regulator, winged helix family K07658 - - 0.000000000000000000000000000000000000000000000000000000000000001448 226.0
HFD2_k127_3000651_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000006328 181.0
HFD2_k127_3005014_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.22e-213 676.0
HFD2_k127_3005014_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 6.007e-199 633.0
HFD2_k127_3005014_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.86 0.0000000000000000000000000000000000000000000000001932 179.0
HFD2_k127_3005014_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000001881 66.0
HFD2_k127_3007329_0 COGs COG3533 conserved K09955 - - 6.717e-203 651.0
HFD2_k127_3007329_1 carbohydrate transport K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 467.0
HFD2_k127_3007329_10 - - - - 0.00000002131 61.0
HFD2_k127_3007329_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 390.0
HFD2_k127_3007329_3 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 361.0
HFD2_k127_3007329_4 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 353.0
HFD2_k127_3007329_5 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000005429 221.0
HFD2_k127_3007329_6 ATP-binding - - - 0.0000000000000000000000000000000000000000000000000000000681 201.0
HFD2_k127_3007329_7 Protein of unknown function (DUF1706) - - - 0.00000000000000000000000000000000004925 139.0
HFD2_k127_3007329_8 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000003999 118.0
HFD2_k127_3007329_9 transposase K07492 - - 0.0000000000000000000000004238 108.0
HFD2_k127_3020755_0 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 522.0
HFD2_k127_3020755_1 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005349 280.0
HFD2_k127_3020755_2 - - - - 0.0000000000000000000000000000000000000000000005397 183.0
HFD2_k127_3020755_3 PFAM regulatory protein, MerR - - - 0.00000000000000000000000000000000006926 141.0
HFD2_k127_3020755_4 Putative restriction endonuclease - - - 0.000000000000000000000000000002429 126.0
HFD2_k127_3021917_0 Peptidase S9, prolyl oligopeptidase active site domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 347.0
HFD2_k127_3021917_1 COG0006 Xaa-Pro aminopeptidase K01262 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9 0.00000000000000000000000000000000000000000000000000000001167 215.0
HFD2_k127_3021917_2 PFAM FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000831 78.0
HFD2_k127_3021917_3 PFAM NB-ARC domain K16247 - - 0.00000000001717 67.0
HFD2_k127_3026988_0 electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 301.0
HFD2_k127_3026988_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000005896 229.0
HFD2_k127_3026988_2 electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000001795 175.0
HFD2_k127_3026988_3 Transcriptional regulatory protein, C terminal K07669,K07672 - - 0.00000000000000000000000000000000000000004116 157.0
HFD2_k127_3026988_4 cheY-homologous receiver domain - - - 0.0000000000000000000000000001473 119.0
HFD2_k127_3026988_6 Transglycosylase associated protein - - - 0.0000197 50.0
HFD2_k127_3026988_7 YbbR-like protein - - - 0.00006513 55.0
HFD2_k127_3035273_0 KaiC K08482 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 535.0
HFD2_k127_3035273_1 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701 - 0.0003404 52.0
HFD2_k127_3049254_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 588.0
HFD2_k127_3049254_1 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000000000000000000000000000001462 171.0
HFD2_k127_3056782_0 Molybdopterin oxidoreductase - - - 0.0 1631.0
HFD2_k127_3056782_1 nitrate reductase beta subunit K00371,K16965,K17048,K17051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.5.1 1.178e-238 741.0
HFD2_k127_3056782_2 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000002003 222.0
HFD2_k127_3056782_3 protein complex oligomerization - - - 0.0000000000000000000000000000000000000000000000000000000007653 210.0
HFD2_k127_3056782_4 histidine kinase, dimerisation and phosphoacceptor region K07673 - 2.7.13.3 0.000000000000000000000000000000000000000000003781 185.0
HFD2_k127_3056782_5 Domain of unknown function (DUF4062) - - - 0.00000000000000001402 93.0
HFD2_k127_3056782_6 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.000000000000003999 82.0
HFD2_k127_3064393_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 554.0
HFD2_k127_3064393_1 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 357.0
HFD2_k127_3064393_2 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 302.0
HFD2_k127_3064393_3 inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000002155 214.0
HFD2_k127_3064393_4 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000002288 205.0
HFD2_k127_3064726_0 Glycosylase K18785 - 2.4.1.319,2.4.1.320 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 379.0
HFD2_k127_3064726_1 Glycosyl Hydrolase Family 88 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 376.0
HFD2_k127_3064726_2 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006777 289.0
HFD2_k127_3064726_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000001148 156.0
HFD2_k127_3064726_4 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000007956 143.0
HFD2_k127_3064726_5 Phosphoesterase family - - - 0.00000113 52.0
HFD2_k127_306518_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 363.0
HFD2_k127_306518_1 SNARE associated Golgi protein K19302 - 3.6.1.27 0.000000000000000000000000000000000000005012 154.0
HFD2_k127_306518_2 PFAM diacylglycerol kinase catalytic region - - - 0.000000000000000000000000000152 127.0
HFD2_k127_306518_3 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000005108 79.0
HFD2_k127_307910_0 formate C-acetyltransferase activity K00656 - 2.3.1.54 0.0 1205.0
HFD2_k127_307910_1 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 364.0
HFD2_k127_307910_2 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003875 285.0
HFD2_k127_307910_3 Helicase conserved C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002207 244.0
HFD2_k127_307910_4 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000008107 237.0
HFD2_k127_307910_5 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000138 159.0
HFD2_k127_307910_6 2'-5' RNA ligase superfamily - - - 0.000005196 57.0
HFD2_k127_3079487_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000008621 261.0
HFD2_k127_3079487_1 carboxylic acid catabolic process - - - 0.000000000000000000000000000000000000000000000000003994 192.0
HFD2_k127_3079487_2 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000001164 168.0
HFD2_k127_3079487_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000002031 91.0
HFD2_k127_3085006_0 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000009286 83.0
HFD2_k127_3085006_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000007701 61.0
HFD2_k127_3089756_0 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 347.0
HFD2_k127_3089756_1 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002193 262.0
HFD2_k127_3089756_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000002 200.0
HFD2_k127_3106533_0 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 308.0
HFD2_k127_3106533_1 ATPase associated with various cellular K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002597 254.0
HFD2_k127_3106533_2 ATPase associated with various cellular K03924 - - 0.000000000000000000000000000000000000000000000000000000008643 200.0
HFD2_k127_3106533_3 Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000000000001741 167.0
HFD2_k127_3106533_4 Domain of unknown function (DUF4129) - - - 0.0000000000000000000000000000677 132.0
HFD2_k127_311117_0 pyrroloquinoline quinone binding - - - 1.668e-194 636.0
HFD2_k127_311117_1 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009919 313.0
HFD2_k127_311117_2 CHAT domain - - - 0.00000000006298 76.0
HFD2_k127_311117_3 NB-ARC domain - - - 0.000001707 62.0
HFD2_k127_311117_4 Glycogen debranching enzyme - - - 0.0006343 43.0
HFD2_k127_311117_5 Parallel beta-helix repeats - - - 0.0009893 51.0
HFD2_k127_3113697_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000002414 209.0
HFD2_k127_3113697_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000001348 139.0
HFD2_k127_3113697_2 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000001593 109.0
HFD2_k127_3113910_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 2.751e-234 751.0
HFD2_k127_3113910_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775,K01929 - 5.1.1.1,6.3.2.10 2.551e-208 676.0
HFD2_k127_3113910_2 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 323.0
HFD2_k127_3113910_3 PFAM Bacterial regulatory proteins, lacI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 313.0
HFD2_k127_3113910_4 ABC-type sugar transport system periplasmic component K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001983 266.0
HFD2_k127_3113910_5 - - - - 0.00000000000000000000000000001204 128.0
HFD2_k127_3113910_6 3-demethylubiquinone-9 3-O-methyltransferase activity K05946 - 2.4.1.187 0.000000000000000002097 89.0
HFD2_k127_3113910_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000001012 56.0
HFD2_k127_3113910_8 Rdx family K07401 - - 0.000000313 55.0
HFD2_k127_311662_0 Enoyl-(Acyl carrier protein) reductase K10780 - 1.3.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 307.0
HFD2_k127_311662_1 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007347 256.0
HFD2_k127_311662_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000007118 231.0
HFD2_k127_311662_3 response regulator, receiver K09763 - - 0.0000000000000000000000000000008962 131.0
HFD2_k127_311662_4 RibD C-terminal domain - - - 0.000000000000000000000006778 102.0
HFD2_k127_311662_5 - - - - 0.00000000000000000003294 93.0
HFD2_k127_3117874_0 cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008635 451.0
HFD2_k127_3117874_1 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 403.0
HFD2_k127_3117874_2 NAD+ diphosphatase activity K03426,K20449 - 1.3.7.1,3.6.1.22 0.000000000000000000000000000000000000000000000000000000000201 212.0
HFD2_k127_3117874_3 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000006203 150.0
HFD2_k127_3117874_4 Alpha/beta hydrolase family - - - 0.000000000000000466 85.0
HFD2_k127_3117874_5 Heat induced stress protein YflT - - - 0.000000001274 68.0
HFD2_k127_3117874_6 2TM domain - - - 0.0004414 48.0
HFD2_k127_3120012_0 Pyruvate phosphate dikinase, PEP pyruvate binding K01006,K01007 - 2.7.9.1,2.7.9.2 5.169e-219 704.0
HFD2_k127_3120012_1 Serine threonine protein kinase K12132 - 2.7.11.1 4.588e-208 662.0
HFD2_k127_3120012_10 PFAM Forkhead-associated protein - - - 0.00000000000000000007288 95.0
HFD2_k127_3120012_11 - - - - 0.000000000000000006258 85.0
HFD2_k127_3120012_12 Branched-chain amino acid transport system / permease component K10440 - - 0.0000000001063 68.0
HFD2_k127_3120012_13 Calcineurin-like phosphoesterase K01081 - 3.1.3.5 0.0008502 49.0
HFD2_k127_3120012_2 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 494.0
HFD2_k127_3120012_3 Two component transcriptional regulator, winged helix family K07667,K07668 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 350.0
HFD2_k127_3120012_4 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 322.0
HFD2_k127_3120012_5 PFAM von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008326 329.0
HFD2_k127_3120012_6 Catalyzes the conversion of L-arabinose to L-ribulose K01804 - 5.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 284.0
HFD2_k127_3120012_7 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000003664 209.0
HFD2_k127_3120012_8 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000001251 182.0
HFD2_k127_3120012_9 NIF3 (NGG1p interacting factor 3) - - - 0.0000000000000000000000000000006686 134.0
HFD2_k127_3132809_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 336.0
HFD2_k127_3132809_1 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 327.0
HFD2_k127_3132809_2 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000009439 108.0
HFD2_k127_3132809_3 Belongs to the 5'-nucleotidase family - - - 0.00001262 59.0
HFD2_k127_3132809_4 IS1 transposase K07480 - - 0.0002061 44.0
HFD2_k127_3134946_0 CRISPR-associated endoribonuclease Cas6 K19091 - - 0.00000000000000000000000000000000000000676 157.0
HFD2_k127_3134946_1 TIGRFAM CRISPR-associated RAMP protein, SSO1426 family - - - 0.000000000000000000000000000000000002076 149.0
HFD2_k127_3134946_2 RAMP superfamily - - - 0.0000000000000009148 89.0
HFD2_k127_3134946_3 TIGRFAM CRISPR-associated RAMP protein, Csx10 family K19134 - - 0.0000000001497 73.0
HFD2_k127_3134946_4 Patatin-like phospholipase K06900 - - 0.0000000001997 73.0
HFD2_k127_3142804_0 peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009864 572.0
HFD2_k127_3142804_1 ABC transporter, ATP-binding protein K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 349.0
HFD2_k127_3142804_10 membrane - - - 0.00000002314 63.0
HFD2_k127_3142804_11 3-demethylubiquinone-9 3-methyltransferase - - - 0.0002294 44.0
HFD2_k127_3142804_2 Protein of unknown function (DUF1214) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 318.0
HFD2_k127_3142804_3 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008513 261.0
HFD2_k127_3142804_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000008405 159.0
HFD2_k127_3142804_5 nitrite reductase [NAD(P)H] activity - - - 0.0000000000000000000000000000000000007646 142.0
HFD2_k127_3142804_6 Protein of unknown function (DUF1254) - - - 0.000000000000000000000000000000000001034 139.0
HFD2_k127_3142804_8 Protein of unknown function (DUF1254) - - - 0.0000000000000000000000000001875 118.0
HFD2_k127_3142804_9 Cell division protein FtsX K02004 - - 0.000000000000000000000005039 109.0
HFD2_k127_3143583_0 dipeptide transport K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 380.0
HFD2_k127_3143583_1 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 306.0
HFD2_k127_3143583_2 cheY-homologous receiver domain - - - 0.00000000000000009452 85.0
HFD2_k127_3143583_3 cheY-homologous receiver domain - - - 0.00000000000001111 79.0
HFD2_k127_315401_0 Glycosyl hydrolases family 2 K01190 - 3.2.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 560.0
HFD2_k127_3160308_0 transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007722 524.0
HFD2_k127_3160308_1 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 400.0
HFD2_k127_3160308_2 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 366.0
HFD2_k127_3163268_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K11959 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 330.0
HFD2_k127_3163268_1 Winged helix-turn helix - - - 0.00000000000000000000000000000000002902 149.0
HFD2_k127_3163268_2 GGDEF domain K02488 - 2.7.7.65 0.000000000000000000000000000101 121.0
HFD2_k127_3163268_3 PAS fold - - - 0.000000000000000000000001207 109.0
HFD2_k127_3163268_4 response regulator - - - 0.0000000000002243 74.0
HFD2_k127_3163268_5 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.0000000001513 63.0
HFD2_k127_3163268_6 PFAM response regulator receiver K02483,K07658,K07668 - - 0.0001847 45.0
HFD2_k127_3164068_0 PFAM Bile acid sodium symporter K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 534.0
HFD2_k127_3164068_1 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000005292 204.0
HFD2_k127_3164068_10 Bacterial extracellular solute-binding protein K02027 - - 0.000008591 59.0
HFD2_k127_3164068_11 - - - - 0.000134 47.0
HFD2_k127_3164068_2 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.0000000000000000000000000000000000002261 143.0
HFD2_k127_3164068_3 TIGRFAM redox-active disulfide protein 2 - - - 0.0000000000000000000000000001126 117.0
HFD2_k127_3164068_4 extracellular solute-binding protein, family 1 K02027 - - 0.000000000000001669 91.0
HFD2_k127_3164068_5 PFAM permease K07089 - - 0.0000000000003568 70.0
HFD2_k127_3164068_6 PFAM Forkhead-associated protein - - - 0.00000000003291 71.0
HFD2_k127_3164068_7 helix_turn_helix, mercury resistance - - - 0.0000000001046 63.0
HFD2_k127_3164068_8 Dsba oxidoreductase - - - 0.00000002576 66.0
HFD2_k127_3164068_9 DNA-binding transcription factor activity K03892 - - 0.000008518 54.0
HFD2_k127_3177306_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 9.6e-309 969.0
HFD2_k127_3177306_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008173 284.0
HFD2_k127_3177306_2 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003348 296.0
HFD2_k127_3177306_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000001225 223.0
HFD2_k127_3177306_4 PFAM low molecular weight phosphotyrosine protein phosphatase K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000001446 181.0
HFD2_k127_3177306_5 Acetyltransferase (GNAT) domain K03830 - - 0.0000000000000000000000000000000000000000000554 166.0
HFD2_k127_3177306_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000004636 149.0
HFD2_k127_3177306_7 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000004505 113.0
HFD2_k127_3177306_8 COG0456 Acetyltransferases K03789 - 2.3.1.128 0.00000004137 61.0
HFD2_k127_3177306_9 ubiE/COQ5 methyltransferase family - - - 0.00000005349 65.0
HFD2_k127_317778_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000000000000000000000000000000000000000000000000000000000001312 242.0
HFD2_k127_317778_1 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 GO:0001505,GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0017144,GO:0019464,GO:0019752,GO:0031405,GO:0031406,GO:0033293,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901681 - 0.000000000000000000000000000000000000001511 150.0
HFD2_k127_317778_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000003695 119.0
HFD2_k127_317778_3 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase K01185,K02395,K19223 - 3.2.1.17 0.00000000000001429 87.0
HFD2_k127_317778_5 Bacterial extracellular solute-binding protein K02027 - - 0.0006659 52.0
HFD2_k127_3180435_0 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008236 423.0
HFD2_k127_3180435_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 414.0
HFD2_k127_3180435_2 Platelet-activating factor acetylhydrolase, isoform II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 370.0
HFD2_k127_3180435_3 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 324.0
HFD2_k127_3180435_4 Pfam Activator of Hsp90 ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001287 241.0
HFD2_k127_3180435_5 Platelet-activating factor acetylhydrolase, isoform II - - - 0.00000000000000000000000000000000000000000000000000000000000000005995 227.0
HFD2_k127_3180435_6 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000001195 124.0
HFD2_k127_3180435_7 PFAM TRAG family protein K03205 - - 0.00000001324 66.0
HFD2_k127_3181320_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 522.0
HFD2_k127_3181320_1 Squalene--hopene cyclase K17811 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009267,GO:0009605,GO:0009607,GO:0009975,GO:0009987,GO:0009991,GO:0010350,GO:0016101,GO:0016102,GO:0016114,GO:0016853,GO:0016872,GO:0019637,GO:0031667,GO:0031668,GO:0031669,GO:0033385,GO:0033554,GO:0035439,GO:0035440,GO:0042594,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071496,GO:0071704,GO:0075136,GO:1901576 5.5.1.16 0.000000000000000000000000000000000000000000000001469 188.0
HFD2_k127_3181320_2 cheY-homologous receiver domain K11443 - - 0.00000000000000000000001684 106.0
HFD2_k127_3181320_3 GHKL domain - - - 0.000000000000000067 85.0
HFD2_k127_3181320_4 cheY-homologous receiver domain - - - 0.0000000007154 66.0
HFD2_k127_3182049_0 PFAM Band 7 protein - - - 3.811e-225 710.0
HFD2_k127_3182049_1 Galactose oxidase, central domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006429 274.0
HFD2_k127_3187755_0 PFAM glycoside hydrolase family 39 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 387.0
HFD2_k127_3187755_1 Aldo/keto reductase family K16950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 328.0
HFD2_k127_3187755_2 PFAM extracellular solute-binding protein, family 3 K02030 - - 0.000000000000000000000000000003404 131.0
HFD2_k127_3187755_3 Bacterial regulatory proteins, tetR family - - - 0.0001622 51.0
HFD2_k127_3190872_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 462.0
HFD2_k127_3190872_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 321.0
HFD2_k127_3190872_2 Sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002841 292.0
HFD2_k127_3190872_3 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000006658 186.0
HFD2_k127_3190872_4 Belongs to the P(II) protein family - - - 0.0000000000000000000000000002931 117.0
HFD2_k127_3198778_0 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 514.0
HFD2_k127_3198778_1 Transcriptional regulator K02529,K07506 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 517.0
HFD2_k127_3198778_2 PFAM Glycoside hydrolase family 42 domain protein K12308 - 3.2.1.23 0.0000000000000000000000000000000000003241 146.0
HFD2_k127_3198778_3 helix_turn_helix, Lux Regulon - - - 0.0003133 43.0
HFD2_k127_3205390_0 AMP-binding enzyme K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000735 426.0
HFD2_k127_3205390_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 324.0
HFD2_k127_3208117_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 611.0
HFD2_k127_3208117_1 PHP domain protein K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000554 555.0
HFD2_k127_3208117_2 - - - - 0.000000191 62.0
HFD2_k127_3214924_0 isochorismatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001292 267.0
HFD2_k127_3214924_1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000000000000000000000000001267 210.0
HFD2_k127_3214924_2 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000004277 128.0
HFD2_k127_3214924_3 protein kinase activity - - - 0.0000000000000000000000000006285 126.0
HFD2_k127_3214924_4 ABC transporter K02003 - - 0.0000000000000000000002871 101.0
HFD2_k127_3214924_5 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K00573 - 2.1.1.77 0.0000000000000002072 87.0
HFD2_k127_3226319_0 PFAM NADH flavin oxidoreductase NADH oxidase K00219,K09461 - 1.14.13.40,1.3.1.34 2.03e-322 1002.0
HFD2_k127_3226319_1 PFAM glycoside hydrolase, family 3 domain protein K05349 - 3.2.1.21 5.953e-196 627.0
HFD2_k127_3226319_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 305.0
HFD2_k127_3226319_3 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000001625 199.0
HFD2_k127_3226319_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000001761 160.0
HFD2_k127_3226319_5 Glycosyl hydrolase family 3 N terminal domain K01188,K05349 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008422,GO:0009056,GO:0009057,GO:0009251,GO:0015926,GO:0016020,GO:0016052,GO:0016787,GO:0016798,GO:0042597,GO:0043170,GO:0044042,GO:0044238,GO:0044464,GO:0071704,GO:0071944,GO:1901575 3.2.1.21 0.0000000000004063 70.0
HFD2_k127_3226319_6 Periplasmic component of amino acid ABC-type transporter signal transduction system K02030 - - 0.0002943 51.0
HFD2_k127_3231911_0 PNKP adenylyltransferase domain, ligase domain - - - 0.0 1222.0
HFD2_k127_3231911_1 transposition K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006998 405.0
HFD2_k127_3231911_2 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000005401 237.0
HFD2_k127_3231911_3 lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000376 210.0
HFD2_k127_3231911_4 - - - - 0.000000000000000000000000000005946 125.0
HFD2_k127_3231911_5 RelE toxin of RelE / RelB toxin-antitoxin system - - - 0.00000000000000000000000008996 110.0
HFD2_k127_3231911_6 Transposase - - - 0.0000000000007309 70.0
HFD2_k127_3233763_0 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K12369 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004835 415.0
HFD2_k127_3233763_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 357.0
HFD2_k127_3259110_0 Saccharopine dehydrogenase NADP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004443 285.0
HFD2_k127_3259110_1 COGs COG1175 ABC-type sugar transport systems permease components K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002598 263.0
HFD2_k127_3259110_2 Psort location Cytoplasmic, score 9.97 K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000006729 179.0
HFD2_k127_3259110_3 SPTR D1CI93 Phophonate C-P lyase system transcriptional regulator PhnF, GntR family K03710 - - 0.00000000000000000000000000000000000000001758 166.0
HFD2_k127_3259110_4 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000293 117.0
HFD2_k127_3259110_5 COG0395 ABC-type sugar transport system, permease component K02026 - - 0.0000000000006678 78.0
HFD2_k127_3259566_0 ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 506.0
HFD2_k127_3259566_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000002894 219.0
HFD2_k127_3259566_2 Histidine kinase - - - 0.000000000000000000000000000000000000000006188 169.0
HFD2_k127_3265105_0 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.0 1245.0
HFD2_k127_3265105_1 TIGRFAM glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000136 287.0
HFD2_k127_3277718_0 PFAM metal-dependent phosphohydrolase, HD sub domain K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 489.0
HFD2_k127_3282852_0 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 368.0
HFD2_k127_3282852_1 Evidence 5 No homology to any previously reported sequences K07156,K07245,K14166 - - 0.00000000000000000000000000000000000000000000000000003601 216.0
HFD2_k127_3282852_2 PFAM Nucleotidyl transferase - - - 0.00000000000000000000000000000000000000282 153.0
HFD2_k127_3282852_3 - - - - 0.000000000000000000001333 102.0
HFD2_k127_3284188_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 379.0
HFD2_k127_3284188_1 histidine kinase HAMP region domain protein K11527 - 2.7.13.3 0.000000000000000000000000000000000000000000002101 182.0
HFD2_k127_3284188_2 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000002031 145.0
HFD2_k127_3284188_3 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000002448 132.0
HFD2_k127_3284188_4 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000378 108.0
HFD2_k127_3284188_5 - - - - 0.00000000000000002659 88.0
HFD2_k127_329353_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009092 373.0
HFD2_k127_329353_1 serine threonine protein kinase K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000004355 226.0
HFD2_k127_329353_2 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000000000000000000000006868 188.0
HFD2_k127_329353_3 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000003017 168.0
HFD2_k127_329353_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00009331 47.0
HFD2_k127_3304420_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 1.027e-231 723.0
HFD2_k127_3306554_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352,K21307 - 1.8.5.5,1.8.5.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 420.0
HFD2_k127_3306554_1 Fe-S-cluster-containing hydrogenase K08358 - - 0.000000000000000000000000000000000000001015 154.0
HFD2_k127_3306554_2 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000001763 109.0
HFD2_k127_3306554_3 gamma-carboxymuconolactone decarboxylase subunit - - - 0.000000000000000000000008128 105.0
HFD2_k127_3311160_0 Domain of unknown function (DUF1929) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 375.0
HFD2_k127_3311160_1 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.00000000000000000000000000000000000000001146 157.0
HFD2_k127_3311160_2 Phage integrase family - - - 0.0000002518 54.0
HFD2_k127_3313574_0 Pfam Anion-transporting ATPase K01551 - 3.6.3.16 7.863e-198 636.0
HFD2_k127_3313574_1 transposition, DNA-mediated K02529,K20971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000797 276.0
HFD2_k127_3313574_2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000129 187.0
HFD2_k127_3313574_3 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000002164 162.0
HFD2_k127_3313574_5 Sigma-70, region 4 K03088 - - 0.0000000000000000000000003482 112.0
HFD2_k127_3313574_6 Arsenical resistance operon trans-acting repressor ArsD - - - 0.00000000000000000000006806 102.0
HFD2_k127_3313574_7 PFAM regulatory protein, ArsR K03892 - - 0.00000000000000002297 83.0
HFD2_k127_3313574_9 Control of competence regulator ComK, YlbF/YmcA - - - 0.0000000054 63.0
HFD2_k127_3324621_0 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 342.0
HFD2_k127_3324621_1 protein histidine kinase activity K05962 - 2.7.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 354.0
HFD2_k127_3324621_2 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002652 270.0
HFD2_k127_3324621_3 TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000002805 178.0
HFD2_k127_3325920_0 PFAM fumarate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 406.0
HFD2_k127_3325920_1 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003733 278.0
HFD2_k127_3325920_2 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.000000000000000000000000000001906 128.0
HFD2_k127_3325920_3 Alpha-Mannosidase K01191,K15524 GO:0003674,GO:0003824,GO:0004553,GO:0004559,GO:0005975,GO:0005996,GO:0006013,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015923,GO:0016787,GO:0016798,GO:0019318,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0071704,GO:1901135,GO:1901564 3.2.1.170,3.2.1.24 0.0000000000000000000009341 108.0
HFD2_k127_3328000_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 2.763e-301 930.0
HFD2_k127_3328000_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 362.0
HFD2_k127_3328000_10 Membrane - - - 0.0000000000000000000000006983 122.0
HFD2_k127_3328000_11 ADP-glyceromanno-heptose 6-epimerase activity K01784,K02473 - 5.1.3.2,5.1.3.7 0.00000000001328 65.0
HFD2_k127_3328000_12 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 0.00000002172 59.0
HFD2_k127_3328000_2 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 324.0
HFD2_k127_3328000_3 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000691 239.0
HFD2_k127_3328000_4 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000001416 231.0
HFD2_k127_3328000_5 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000006694 233.0
HFD2_k127_3328000_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000004906 158.0
HFD2_k127_3328000_7 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000001378 151.0
HFD2_k127_3328000_8 - - - - 0.0000000000000000000000000002249 116.0
HFD2_k127_3328000_9 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.000000000000000000000000006666 112.0
HFD2_k127_3330156_0 Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005861 295.0
HFD2_k127_3330156_1 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001115 277.0
HFD2_k127_3330156_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000004864 232.0
HFD2_k127_3330156_3 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000008086 213.0
HFD2_k127_3330156_4 response to heat - - - 0.000000000000000000000001344 116.0
HFD2_k127_3330156_5 sh3 domain protein - - - 0.00002434 56.0
HFD2_k127_3332958_0 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 555.0
HFD2_k127_3332958_1 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000002829 125.0
HFD2_k127_3332958_2 PFAM Peptidase M23 - - - 0.0000000000000000000000000002603 130.0
HFD2_k127_3332958_3 - - - - 0.0000000000000635 79.0
HFD2_k127_3332958_4 Dienelactone hydrolase family - - - 0.0000007763 58.0
HFD2_k127_33585_0 Feruloyl esterase K21105 - 3.1.1.102 1.213e-201 645.0
HFD2_k127_33585_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 546.0
HFD2_k127_33585_2 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 315.0
HFD2_k127_33585_3 transposition, DNA-mediated K02529,K20971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 309.0
HFD2_k127_33585_4 Psort location Cytoplasmic, score K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000002242 269.0
HFD2_k127_33585_5 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000000005483 181.0
HFD2_k127_33585_6 Glycosyl hydrolases family 2, sugar binding domain - - - 0.00000000000000000000000001301 119.0
HFD2_k127_33585_7 PFAM ABC transporter K01995,K01998 - - 0.000000002566 59.0
HFD2_k127_33585_8 Belongs to the glycosyl hydrolase 43 family - - - 0.000000005761 66.0
HFD2_k127_33585_9 PFAM IS1 transposase K07480 - - 0.000127 51.0
HFD2_k127_3367036_0 PhoQ Sensor - - - 1.696e-226 746.0
HFD2_k127_3367036_1 Dipeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 589.0
HFD2_k127_3367036_10 PFAM WD domain, G-beta repeat - - - 0.00000000000000000000000000000000001158 156.0
HFD2_k127_3367036_11 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000009021 104.0
HFD2_k127_3367036_12 - - - - 0.00000000000002811 83.0
HFD2_k127_3367036_13 Parallel beta-helix repeats - - - 0.000000002291 70.0
HFD2_k127_3367036_14 HD domain K18967 - 2.7.7.65 0.00000002495 66.0
HFD2_k127_3367036_2 helix_turn_helix, Lux Regulon K03556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 603.0
HFD2_k127_3367036_3 Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose K16212 - 2.4.1.281 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005886 541.0
HFD2_k127_3367036_4 solute-binding protein K10117 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006149 441.0
HFD2_k127_3367036_5 transcriptional regulator domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 327.0
HFD2_k127_3367036_6 PFAM Serine threonine protein kinase-related K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000005085 269.0
HFD2_k127_3367036_7 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000145 205.0
HFD2_k127_3367036_8 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000107 194.0
HFD2_k127_3367036_9 Flavodoxin domain K00230 - 1.3.5.3 0.00000000000000000000000000000000000000000008055 166.0
HFD2_k127_3373944_0 xylulokinase activity K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 557.0
HFD2_k127_3373944_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 391.0
HFD2_k127_3373944_2 Glucose-6-phosphate isomerase (GPI) K06859 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003684 282.0
HFD2_k127_3373944_3 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000001755 263.0
HFD2_k127_3377425_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 352.0
HFD2_k127_3377425_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001524 284.0
HFD2_k127_3377425_2 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004261 256.0
HFD2_k127_3381329_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 1.373e-271 843.0
HFD2_k127_3381329_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00334,K00335 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 6.288e-248 776.0
HFD2_k127_3381329_10 - - - - 0.00000000000000000000000000000000000000000000000000002945 191.0
HFD2_k127_3381329_11 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000004814 173.0
HFD2_k127_3381329_12 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000001867 177.0
HFD2_k127_3381329_13 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000005833 145.0
HFD2_k127_3381329_14 AraC-like ligand binding domain - - - 0.00001043 49.0
HFD2_k127_3381329_2 DEAD DEAH box helicase K03724 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000724 538.0
HFD2_k127_3381329_3 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 510.0
HFD2_k127_3381329_4 tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 433.0
HFD2_k127_3381329_5 Formate/nitrite transporter K06212 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 366.0
HFD2_k127_3381329_6 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 343.0
HFD2_k127_3381329_7 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 307.0
HFD2_k127_3381329_8 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002819 258.0
HFD2_k127_3381329_9 dihydrofolate reductase activity - - - 0.0000000000000000000000000000000000000000000000000000003681 200.0
HFD2_k127_3382303_0 TIGRFAM dihydroxyacetone kinase, DhaK subunit K05878 - 2.7.1.121 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 591.0
HFD2_k127_3382303_1 TIGRFAM dihydroxyacetone kinase, L subunit K05879 - 2.7.1.121 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002803 279.0
HFD2_k127_3382303_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000001013 247.0
HFD2_k127_3382303_3 Belongs to the MIP aquaporin (TC 1.A.8) family K02440 - - 0.00000000000000002782 83.0
HFD2_k127_3383368_0 helix_turn_helix, Lux Regulon K03556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007521 602.0
HFD2_k127_3383368_1 Putative transposase of IS4/5 family (DUF4096) - - - 0.000000000000000000000000000000000000000004695 163.0
HFD2_k127_3383368_2 similarity to GB CAD86359.1 - - - 0.00000000000000000000000000000002469 129.0
HFD2_k127_3383368_3 PFAM transposase IS66 K07484 - - 0.00000000000000000000000000000003401 135.0
HFD2_k127_3383368_4 PFAM YGGT family - - - 0.00000000000000000000002277 104.0
HFD2_k127_3383368_5 Belongs to the UPF0337 (CsbD) family - - - 0.000000000000000000001678 96.0
HFD2_k127_3383368_6 Transglycosylase associated protein - - - 0.000000000000000000009335 94.0
HFD2_k127_3383368_7 Transglycosylase associated protein - - - 0.00000000000003127 76.0
HFD2_k127_3383368_9 YtxH-like protein - - - 0.000134 47.0
HFD2_k127_3388511_0 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000001418 156.0
HFD2_k127_3404477_0 Integrase catalytic K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003608 288.0
HFD2_k127_3404477_1 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002777 279.0
HFD2_k127_3404477_2 PFAM helix-turn-helix domain protein - - - 0.000000000000000000000000000000000000000000000001636 185.0
HFD2_k127_3404477_3 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000001744 175.0
HFD2_k127_3404477_4 PFAM transposase IS66 K07484 - - 0.0000000000000000000000000000007414 128.0
HFD2_k127_3422147_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007744 276.0
HFD2_k127_3422147_1 Squalene--hopene cyclase K17811 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009267,GO:0009605,GO:0009607,GO:0009975,GO:0009987,GO:0009991,GO:0010350,GO:0016101,GO:0016102,GO:0016114,GO:0016853,GO:0016872,GO:0019637,GO:0031667,GO:0031668,GO:0031669,GO:0033385,GO:0033554,GO:0035439,GO:0035440,GO:0042594,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071496,GO:0071704,GO:0075136,GO:1901576 5.5.1.16 0.0000000000000000000000000000000000000000009661 174.0
HFD2_k127_3422147_2 Peptidogalycan biosysnthesis/recognition - - - 0.00000000001258 76.0
HFD2_k127_3422147_3 Bacterial extracellular solute-binding protein K02027 - - 0.00000007581 66.0
HFD2_k127_3422147_4 Acetyltransferase (GNAT) domain - - - 0.0000002098 62.0
HFD2_k127_3427269_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 615.0
HFD2_k127_3427269_1 PFAM ABC transporter related K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009119 445.0
HFD2_k127_3427269_2 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis K03816 - 2.4.2.22 0.00000000000000000000000000000000000000000000000000000000000002092 220.0
HFD2_k127_3427269_3 Xylose isomerase-like TIM barrel - - - 0.00000000000000001749 86.0
HFD2_k127_3429510_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K12952 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 534.0
HFD2_k127_3429510_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001892 269.0
HFD2_k127_3429510_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000721 271.0
HFD2_k127_3429510_3 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004882 263.0
HFD2_k127_3429978_0 Serine aminopeptidase, S33 K01048 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000002407 240.0
HFD2_k127_3429978_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000001203 82.0
HFD2_k127_3429978_2 Acetyltransferase (GNAT) domain - - - 0.000000000000002812 83.0
HFD2_k127_3429978_3 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.0002294 44.0
HFD2_k127_3431749_0 PFAM Transglutaminase-like superfamily K22452 - 2.3.2.13 0.000000000000000003883 97.0
HFD2_k127_3431749_1 Bacterial transcriptional activator domain - - - 0.0001143 55.0
HFD2_k127_3444583_0 Glucodextranase, domain N K01178 - 3.2.1.3 0.0 1018.0
HFD2_k127_3444583_1 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003683 271.0
HFD2_k127_3444583_2 DDE domain K18320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008205 268.0
HFD2_k127_3444583_3 SnoaL-like polyketide cyclase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000246 195.0
HFD2_k127_3444583_4 PFAM IS66 Orf2 family protein K07484 - - 0.00000000000003502 72.0
HFD2_k127_3450535_0 Aminotransferase class I and II K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 574.0
HFD2_k127_3450535_1 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 331.0
HFD2_k127_3450535_10 Tetratricopeptide TPR_2 repeat protein - - - 0.00000006234 64.0
HFD2_k127_3450535_2 ATP:ADP antiporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 309.0
HFD2_k127_3450535_3 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002138 286.0
HFD2_k127_3450535_4 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004736 259.0
HFD2_k127_3450535_5 Glycosyl Transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000006198 249.0
HFD2_k127_3450535_6 - - - - 0.0000000000000000000000000000000000000000000000000000000004974 212.0
HFD2_k127_3450535_7 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000002059 195.0
HFD2_k127_3450535_8 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000001135 196.0
HFD2_k127_3450535_9 - - - - 0.000000000000000000000000000004389 133.0
HFD2_k127_3457178_0 TIGRFAM MazG family protein K02499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 477.0
HFD2_k127_3457178_1 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000003031 144.0
HFD2_k127_3457178_2 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000002292 72.0
HFD2_k127_3457178_3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07662 - - 0.00000000003476 69.0
HFD2_k127_3457178_4 sh3 domain protein - - - 0.0000004028 63.0
HFD2_k127_3464355_0 polysaccharide catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 563.0
HFD2_k127_3464355_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 404.0
HFD2_k127_3464355_10 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000000002918 136.0
HFD2_k127_3464355_11 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000001376 145.0
HFD2_k127_3464355_12 - - - - 0.0000000000000000000000000000007483 130.0
HFD2_k127_3464355_13 Extracellular solute-binding protein K02027,K15770 - - 0.00000000000000000123 99.0
HFD2_k127_3464355_14 HNH endonuclease K07451 - - 0.000000000000000002593 88.0
HFD2_k127_3464355_15 HNH endonuclease K07451 - - 0.00000000000000000758 87.0
HFD2_k127_3464355_16 AntiSigma factor - - - 0.00000000000193 77.0
HFD2_k127_3464355_17 helix_turn_helix, Lux Regulon - - - 0.000000000004915 79.0
HFD2_k127_3464355_2 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 407.0
HFD2_k127_3464355_3 COGs COG1131 ABC-type multidrug transport system ATPase component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 328.0
HFD2_k127_3464355_4 Periplasmic binding protein-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002057 256.0
HFD2_k127_3464355_5 Binding-protein-dependent transport system inner membrane component K02025,K10189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002523 252.0
HFD2_k127_3464355_6 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000007349 243.0
HFD2_k127_3464355_7 Binding-protein-dependent transport system inner membrane component K17236 - - 0.000000000000000000000000000000000000000000000000000000000000853 220.0
HFD2_k127_3464355_8 Cache domain - - - 0.00000000000000000000000000000000000000000000000000003885 211.0
HFD2_k127_3464355_9 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000003489 166.0
HFD2_k127_3473038_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 578.0
HFD2_k127_3473038_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 485.0
HFD2_k127_3473038_2 ATPase family associated with various cellular activities (AAA) K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 469.0
HFD2_k127_3473038_3 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 385.0
HFD2_k127_3473038_4 Predicted membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 352.0
HFD2_k127_3473038_5 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 325.0
HFD2_k127_3473038_6 Peptidase M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001084 271.0
HFD2_k127_3476551_0 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004565 275.0
HFD2_k127_3476551_1 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000001005 233.0
HFD2_k127_3476551_2 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000005153 181.0
HFD2_k127_3476551_3 - - - - 0.000000000000000000003211 106.0
HFD2_k127_3477166_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044464,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600 3.6.3.14,3.6.3.15 2.454e-231 730.0
HFD2_k127_3477166_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 598.0
HFD2_k127_3477166_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000001634 172.0
HFD2_k127_3477166_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000000000000000000000000000000001868 154.0
HFD2_k127_3477166_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000007401 68.0
HFD2_k127_348681_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006781 605.0
HFD2_k127_348681_1 PFAM Methicillin resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008396 325.0
HFD2_k127_348681_10 domain, Protein - - - 0.0000000000000000002508 100.0
HFD2_k127_348681_11 - - - - 0.00000000000000005941 86.0
HFD2_k127_348681_12 extracellular matrix structural constituent - - - 0.0000001257 63.0
HFD2_k127_348681_13 COG3103 SH3 domain protein K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.000003042 59.0
HFD2_k127_348681_14 domain protein associated with RNAses G and E K07586 - - 0.000008726 53.0
HFD2_k127_348681_15 PFAM RNA binding S1 domain protein K02945 - - 0.00004522 49.0
HFD2_k127_348681_2 DNA alkylation repair - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 323.0
HFD2_k127_348681_3 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002171 291.0
HFD2_k127_348681_4 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 GO:0002252,GO:0002376,GO:0003674,GO:0003824,GO:0006464,GO:0006476,GO:0006807,GO:0006935,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018205,GO:0019213,GO:0019538,GO:0033558,GO:0034979,GO:0034983,GO:0035601,GO:0036048,GO:0036049,GO:0036055,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051607,GO:0051704,GO:0051707,GO:0071704,GO:0098542,GO:0098732,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000001776 249.0
HFD2_k127_348681_5 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000003099 246.0
HFD2_k127_348681_6 Protein of unknown function (DUF1706) - - - 0.0000000000000000000000000000000000000000007591 163.0
HFD2_k127_348681_7 PFAM response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000000000002931 119.0
HFD2_k127_348681_8 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000437 117.0
HFD2_k127_348681_9 stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000007573 98.0
HFD2_k127_34869_0 metal ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 610.0
HFD2_k127_34869_1 - - - - 0.00000000000000000000000000000000000018 143.0
HFD2_k127_3487722_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 543.0
HFD2_k127_3487722_1 tRNA-splicing ligase RtcB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 468.0
HFD2_k127_3487722_2 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 336.0
HFD2_k127_3490278_0 Bacterial alpha-L-rhamnosidase C-terminal domain K05989 - 3.2.1.40 0.0 1266.0
HFD2_k127_3490278_1 Type II/IV secretion system protein K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009455 582.0
HFD2_k127_3490278_2 Binding-protein-dependent transport systems inner membrane component K10119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003454 266.0
HFD2_k127_3490278_3 Integrase catalytic - - - 0.000000000000000000000000000000000000000000001678 173.0
HFD2_k127_3490278_4 Protein kinase domain - - - 0.00000000000000000000000000000000000001775 166.0
HFD2_k127_3490278_5 PFAM Integrase catalytic - - - 0.0000000000000001141 81.0
HFD2_k127_3490278_6 COG5595 Zn-ribbon-containing, possibly nucleic-acid-binding protein - - - 0.000000000000001092 81.0
HFD2_k127_3490278_7 - - - - 0.000009169 55.0
HFD2_k127_3508953_0 protein import - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 310.0
HFD2_k127_3508953_1 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000006466 235.0
HFD2_k127_3508953_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000000001378 154.0
HFD2_k127_3521091_0 ABC transporter K06147 - - 2.543e-279 866.0
HFD2_k127_3521091_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 374.0
HFD2_k127_3521091_10 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.000000000000000000000005041 111.0
HFD2_k127_3521091_11 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000008701 85.0
HFD2_k127_3521091_12 CGMP-dependent protein kinase. Source PGD - - - 0.000002985 60.0
HFD2_k127_3521091_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 313.0
HFD2_k127_3521091_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002948 276.0
HFD2_k127_3521091_4 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206,K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003622 279.0
HFD2_k127_3521091_5 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000001483 264.0
HFD2_k127_3521091_6 PFAM peptidase M1, membrane alanine aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000029 242.0
HFD2_k127_3521091_7 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000000000000000000001293 223.0
HFD2_k127_3521091_8 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000002226 148.0
HFD2_k127_3521091_9 Bacterial PH domain K08981 - - 0.0000000000000000000000000007229 130.0
HFD2_k127_3527244_0 Major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 302.0
HFD2_k127_3527244_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000007774 235.0
HFD2_k127_3527244_2 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000004963 156.0
HFD2_k127_3527244_3 PFAM Forkhead-associated protein - - - 0.0000000000000000000000000001777 124.0
HFD2_k127_3527244_4 PFAM peptidase S16 lon domain protein K07157 - - 0.00000000000000007997 82.0
HFD2_k127_3531448_0 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 299.0
HFD2_k127_3531448_1 ABC-type dipeptide transport system periplasmic component K02035 - - 0.00000000000000000000000000000000000000000000000000000000003157 217.0
HFD2_k127_3531448_2 PFAM glycoside hydrolase, family 10 - - - 0.0000000000000000000000000000000001053 142.0
HFD2_k127_3531448_3 chitin deacetylase K22278 - 3.5.1.104 0.0000000000000000000000001359 115.0
HFD2_k127_3531448_4 - - - - 0.0000000000000000000000004888 110.0
HFD2_k127_3548933_0 ABC transporter transmembrane region K06147 - - 2.71e-225 716.0
HFD2_k127_3548933_1 NTF2-like N-terminal transpeptidase domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001819 275.0
HFD2_k127_3548933_2 Cytidylyltransferase-like - - - 0.000000000000000000000000000000000000000003847 162.0
HFD2_k127_3548933_3 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000218 95.0
HFD2_k127_3565940_0 AAA domain K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008853 295.0
HFD2_k127_3565940_1 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.0000000000000000000000000000000000000000000000003388 181.0
HFD2_k127_3565940_2 Cupin domain - - - 0.0000000000000000000000000000000000008314 143.0
HFD2_k127_3565940_3 metal cluster binding K06940 - - 0.000000000000000000000000000000008644 136.0
HFD2_k127_3570028_0 FtsX-like permease family K02004 - - 0.0000000000002477 84.0
HFD2_k127_3578298_0 Glycosyl transferase K00702 - 2.4.1.20 0.0 1247.0
HFD2_k127_3578298_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 432.0
HFD2_k127_3578298_2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 365.0
HFD2_k127_3578298_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 321.0
HFD2_k127_3578298_4 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000001191 174.0
HFD2_k127_3578298_5 Thioredoxin - - - 0.00000000000000000000000000000000000000003692 162.0
HFD2_k127_3619349_0 PFAM Mo-co oxidoreductase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 350.0
HFD2_k127_3619349_1 aminoglycoside K00662 - 2.3.1.81 0.00000000000000000000000000000000003169 136.0
HFD2_k127_3619349_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K04088 - - 0.0000000000000000000000000004236 114.0
HFD2_k127_3627355_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.559e-204 650.0
HFD2_k127_3627355_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 467.0
HFD2_k127_3627355_10 O-Antigen ligase - - - 0.0000000000000000000000000000000000007032 162.0
HFD2_k127_3627355_11 Putative regulatory protein - - - 0.000000000000000000000000000001577 126.0
HFD2_k127_3627355_13 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000009692 76.0
HFD2_k127_3627355_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 395.0
HFD2_k127_3627355_3 Sugar kinase of the NBD HSP70 family, may containing an N-terminal HTH domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 306.0
HFD2_k127_3627355_4 pathogenesis K21471,K21687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006842 277.0
HFD2_k127_3627355_5 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000689 282.0
HFD2_k127_3627355_6 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000001145 229.0
HFD2_k127_3627355_7 PFAM Appr-1-p processing domain protein - - - 0.00000000000000000000000000000000000000000000000001757 185.0
HFD2_k127_3627355_8 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000005262 171.0
HFD2_k127_3627355_9 PFAM Rhomboid family protein K19225 - 3.4.21.105 0.0000000000000000000000000000000000001191 152.0
HFD2_k127_3628814_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 422.0
HFD2_k127_3628814_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005652 361.0
HFD2_k127_3628814_2 Copper resistance protein D K14166 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000002967 132.0
HFD2_k127_3628814_3 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.000000001915 61.0
HFD2_k127_3633213_0 COGs COG3547 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003873 247.0
HFD2_k127_3633213_1 Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000001694 220.0
HFD2_k127_3633213_10 Belongs to the glycosyl hydrolase 13 family - - - 0.0000004548 59.0
HFD2_k127_3633213_11 PFAM glycosyl transferase, family 51 - - - 0.0002221 56.0
HFD2_k127_3633213_2 Anaphase-promoting complex subunit 4 WD40 domain - - - 0.0000000000000000000000000000000000000000000000009247 188.0
HFD2_k127_3633213_3 trisaccharide binding K03556 - - 0.000000000000000000000000000000000000004054 166.0
HFD2_k127_3633213_4 Phage integrase family - - - 0.000000000000000003866 85.0
HFD2_k127_3633213_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K20444 - - 0.000000000000000118 97.0
HFD2_k127_3633213_6 Heavy-metal-associated domain K17686 GO:0000041,GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0016020,GO:0030001,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0071944 3.6.3.54 0.0000000000000009663 79.0
HFD2_k127_3633213_7 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000002855 89.0
HFD2_k127_3633213_9 PFAM TPR repeat-containing protein - - - 0.00000000006248 76.0
HFD2_k127_3635973_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K02574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001103 282.0
HFD2_k127_3635973_1 4 iron, 4 sulfur cluster binding K00528,K02574,K07098 - 1.18.1.2,1.19.1.1 0.000000000000000001653 93.0
HFD2_k127_3635973_2 - - - - 0.000000001686 65.0
HFD2_k127_3636082_0 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 460.0
HFD2_k127_3641601_0 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 348.0
HFD2_k127_3641601_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 302.0
HFD2_k127_3641601_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000603 260.0
HFD2_k127_3641601_3 Predicted membrane protein (DUF2085) - - - 0.000000000000000000000000000000000000000000005008 175.0
HFD2_k127_3641601_4 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase - - - 0.0000000000000000000000000000002126 129.0
HFD2_k127_3641601_5 lyase activity - - - 0.000007818 56.0
HFD2_k127_3641601_6 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.0001803 53.0
HFD2_k127_3642198_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 9.599e-207 668.0
HFD2_k127_3642198_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 548.0
HFD2_k127_3642198_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009226 370.0
HFD2_k127_3642198_3 Polysaccharide biosynthesis protein K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000001015 281.0
HFD2_k127_3642198_4 Glycosyl hydrolase 36 superfamily, catalytic domain K00702 - 2.4.1.20 0.0000000000000000000000000000000000000000000000000000000000001408 215.0
HFD2_k127_3642198_5 domain, Protein - - - 0.0000000002112 72.0
HFD2_k127_3642295_0 PFAM Tetratricopeptide repeat - - - 0.0 1107.0
HFD2_k127_3642295_1 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005301 287.0
HFD2_k127_3642295_2 - - - - 0.0000000000000003728 88.0
HFD2_k127_3646421_0 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 440.0
HFD2_k127_3646421_1 domain, Protein - - - 0.000000000000000000000000000000000000000000000009338 199.0
HFD2_k127_3646421_2 RTX toxins and related Ca2 binding proteins - - - 0.000000000000000000002367 112.0
HFD2_k127_3649458_0 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 586.0
HFD2_k127_3649458_1 PFAM Bacterial extracellular solute-binding protein K15770 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007015 274.0
HFD2_k127_3649458_2 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003868 266.0
HFD2_k127_3649458_3 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000001321 240.0
HFD2_k127_3649458_4 helix_turn _helix lactose operon repressor - - - 0.000000000000000000000000000000000000000000000000000004333 203.0
HFD2_k127_3649458_5 spore germination - - - 0.0000000000000000000000000000000000000000000000000001836 198.0
HFD2_k127_3652013_0 glycosyl transferase family 8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003144 278.0
HFD2_k127_3652013_1 Nudix hydrolase - - - 0.00000000000000000000000000000000001289 146.0
HFD2_k127_3652013_2 Putative zincin peptidase - - - 0.0000000000009301 78.0
HFD2_k127_3652013_3 - - - - 0.0002336 46.0
HFD2_k127_3661327_0 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 610.0
HFD2_k127_3661327_1 NAD-dependent epimerase dehydratase K01784,K12454 - 5.1.3.10,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004067 422.0
HFD2_k127_3661327_2 PFAM Alpha beta hydrolase fold-3 domain protein K14731 - 3.1.1.83 0.00000000000000000000000000001081 122.0
HFD2_k127_3661327_3 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.000000000000000000000001171 108.0
HFD2_k127_3661327_4 helix_turn_helix, Lux Regulon - - - 0.000000000000001446 78.0
HFD2_k127_3663207_0 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 310.0
HFD2_k127_3663207_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001048 261.0
HFD2_k127_3663207_2 nucleotidyl transferase K15669 - 2.7.7.71 0.000000008634 58.0
HFD2_k127_3663207_3 - - - - 0.00004461 47.0
HFD2_k127_3674091_0 Tex-like protein N-terminal domain K06959 - - 1.022e-296 926.0
HFD2_k127_3674091_1 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 9.501e-247 775.0
HFD2_k127_3674091_2 inorganic diphosphatase activity K15986 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001443 291.0
HFD2_k127_3674091_3 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000008253 231.0
HFD2_k127_3674091_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000002853 67.0
HFD2_k127_3676631_0 PFAM ABC transporter related K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 316.0
HFD2_k127_3676631_1 LysM domain K21449,K22278 - 3.5.1.104 0.000000000000000000001548 109.0
HFD2_k127_3676631_2 PFAM VanW family protein - - - 0.0000000002899 73.0
HFD2_k127_3676631_3 Protein of unknown function (DUF1236) - - - 0.0002436 54.0
HFD2_k127_3678089_0 Deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 512.0
HFD2_k127_3678089_1 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007026 278.0
HFD2_k127_3678089_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000009327 205.0
HFD2_k127_3678089_3 - - - - 0.00000000000000000000007678 100.0
HFD2_k127_3678139_0 efflux transmembrane transporter activity K02004 - - 7.961e-227 726.0
HFD2_k127_3678139_1 COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003 - - 0.00000000000000005013 81.0
HFD2_k127_3682837_0 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 353.0
HFD2_k127_3682837_1 XdhC Rossmann domain K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001492 268.0
HFD2_k127_3682837_2 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000000000000000000000000000001829 260.0
HFD2_k127_3682837_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000002195 251.0
HFD2_k127_3682837_4 response regulator K02479,K07695 GO:0001666,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009405,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0016020,GO:0018995,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0022611,GO:0030312,GO:0030430,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032502,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0036293,GO:0043656,GO:0043657,GO:0044174,GO:0044215,GO:0044216,GO:0044217,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070482,GO:0071944,GO:0072493,GO:0080090,GO:0080134,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1902882,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000005546 159.0
HFD2_k127_3682837_5 - - - - 0.0000000000000000000000000004107 123.0
HFD2_k127_3682837_6 Diguanylate cyclase - - - 0.000000000002406 75.0
HFD2_k127_3689113_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 4.867e-314 971.0
HFD2_k127_3689113_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 292.0
HFD2_k127_3689113_2 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002989 273.0
HFD2_k127_3689113_3 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000001053 263.0
HFD2_k127_3689113_4 self proteolysis - - - 0.000000000000000000000000000000000000000007771 168.0
HFD2_k127_3689113_5 - - - - 0.00000000000000001067 97.0
HFD2_k127_3689113_6 Cytochrome c K08738 - - 0.000000000000002596 84.0
HFD2_k127_3689113_7 HEAT repeat - - - 0.0000194 56.0
HFD2_k127_3689113_8 - - - - 0.0007236 47.0
HFD2_k127_3692670_0 PFAM glycoside hydrolase, family 3 domain protein K05349 - 3.2.1.21 0.0 1033.0
HFD2_k127_3692670_1 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 5.424e-235 745.0
HFD2_k127_3692670_2 ABC transporter (Permease K10118 - - 0.00000000000000000000000000000000000000000000000000000000000000000008236 242.0
HFD2_k127_3692670_3 Binding-protein-dependent transport system inner membrane component K10119,K10202 - - 0.0000000000000000000000000000000000000000000000000000000001515 213.0
HFD2_k127_3692670_4 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000001811 91.0
HFD2_k127_3694222_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000001319 183.0
HFD2_k127_3694222_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000001703 98.0
HFD2_k127_3694222_2 Sigma-70, region 4 K03088 - - 0.00000000000000009118 91.0
HFD2_k127_3694222_3 Domain present in PSD-95, Dlg, and ZO-1/2. K08372 - - 0.000000008913 67.0
HFD2_k127_3694222_4 sequence-specific DNA binding - - - 0.0000002003 59.0
HFD2_k127_3695011_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 499.0
HFD2_k127_3695011_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 470.0
HFD2_k127_3695011_2 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 372.0
HFD2_k127_3695011_3 Haem-binding domain - - - 0.00000000000000000000000000000000000000000003407 165.0
HFD2_k127_3695011_4 - - - - 0.000000000000000000000000000000002363 138.0
HFD2_k127_3695011_5 integral membrane protein - - - 0.00000000000000000000000000000006267 139.0
HFD2_k127_3695011_6 self proteolysis - - - 0.0000000000003696 79.0
HFD2_k127_3696044_0 transposase activity K07495 - - 0.0000000000000000000000000000000000000000002113 165.0
HFD2_k127_3696044_1 DinB family - - - 0.0000000000000000000000000000000000000000003884 164.0
HFD2_k127_3696044_2 LUD domain - - - 0.00000000000000000000000000000000000002139 151.0
HFD2_k127_3696044_3 Iron dependent repressor, N-terminal DNA binding domain - - - 0.0000000000000004801 84.0
HFD2_k127_3696044_4 Integrase catalytic - - - 0.000000000000001666 79.0
HFD2_k127_3696044_5 - - - - 0.0000000002408 67.0
HFD2_k127_3702349_0 COG0520 Selenocysteine lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 560.0
HFD2_k127_3702349_1 udp-glucose 4-epimerase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 520.0
HFD2_k127_3702349_10 His Kinase A (phosphoacceptor) domain - - - 0.0000000008049 71.0
HFD2_k127_3702349_11 DJ-1/PfpI family K18199 - 4.2.1.103 0.00000001085 64.0
HFD2_k127_3702349_12 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.00000002188 61.0
HFD2_k127_3702349_13 DDE superfamily endonuclease - - - 0.0000007219 55.0
HFD2_k127_3702349_14 PFAM binding-protein-dependent transport systems inner membrane component - - - 0.000002304 49.0
HFD2_k127_3702349_15 polysaccharide catabolic process - - - 0.00001415 57.0
HFD2_k127_3702349_16 Integrase catalytic - - - 0.0002544 44.0
HFD2_k127_3702349_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 441.0
HFD2_k127_3702349_3 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 389.0
HFD2_k127_3702349_4 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 376.0
HFD2_k127_3702349_5 NB-ARC domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000744 372.0
HFD2_k127_3702349_6 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 338.0
HFD2_k127_3702349_7 PFAM isochorismatase hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 287.0
HFD2_k127_3702349_8 Serine/Threonine protein kinases, catalytic domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000003294 243.0
HFD2_k127_3702349_9 Serine aminopeptidase, S33 - - - 0.000000000000000000002782 109.0
HFD2_k127_3709997_0 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.000000000000000000000000000000000000000000000000000000000000001856 237.0
HFD2_k127_3709997_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000001258 120.0
HFD2_k127_3709997_2 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000001631 115.0
HFD2_k127_3709997_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000843 88.0
HFD2_k127_3709997_4 Serine threonine protein kinase K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.0001835 54.0
HFD2_k127_371151_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000631 298.0
HFD2_k127_371151_1 PFAM NMT1 THI5 like domain protein K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004773 274.0
HFD2_k127_371151_2 Histidine kinase-, DNA gyrase B-, and HSP90-like - - - 0.000000000000000000000000000000000000000000000001266 186.0
HFD2_k127_371151_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000001403 179.0
HFD2_k127_371151_4 LuxR family transcriptional regulator K07694,K11618 - - 0.00000000000000000000000000000000000000000000008924 177.0
HFD2_k127_371151_5 4-vinyl reductase, 4VR - - - 0.000000000000000000000000000000000000000002489 162.0
HFD2_k127_371151_6 PFAM response regulator receiver K11443 - - 0.000000000000001101 82.0
HFD2_k127_371151_7 cheY-homologous receiver domain - - - 0.0000000000008929 75.0
HFD2_k127_3712119_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 577.0
HFD2_k127_3712119_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 544.0
HFD2_k127_3712119_10 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000001625 61.0
HFD2_k127_3712119_2 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 534.0
HFD2_k127_3712119_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006641 385.0
HFD2_k127_3712119_4 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 323.0
HFD2_k127_3712119_5 PFAM thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000004549 265.0
HFD2_k127_3712119_7 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000006138 179.0
HFD2_k127_3712119_8 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000003536 151.0
HFD2_k127_3712119_9 PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.00000000000000000000000001171 113.0
HFD2_k127_3717113_0 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 310.0
HFD2_k127_3717113_1 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000002867 233.0
HFD2_k127_3725613_0 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000198 207.0
HFD2_k127_3725613_1 Belongs to the glycosyl hydrolase 32 family - - - 0.00000000000000000000000000000004817 145.0
HFD2_k127_3725613_3 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000002498 93.0
HFD2_k127_3725613_4 PFAM NAD-dependent epimerase dehydratase K00067 - 1.1.1.133 0.00000001457 59.0
HFD2_k127_3731868_0 CO dehydrogenase flavoprotein C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 518.0
HFD2_k127_3731868_1 DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005795 275.0
HFD2_k127_3731868_2 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000007631 196.0
HFD2_k127_3731868_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000001622 126.0
HFD2_k127_3731868_4 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.000000001428 59.0
HFD2_k127_3732925_0 PFAM Dak phosphatase K07030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 464.0
HFD2_k127_3732925_1 PFAM metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001736 272.0
HFD2_k127_3732925_2 PFAM Methylated-DNA- protein -cysteine S-methyltransferase, DNA binding K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000001187 177.0
HFD2_k127_3732925_3 Protein conserved in bacteria - - - 0.00000000000000000000000001242 113.0
HFD2_k127_3733314_0 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 364.0
HFD2_k127_3733314_1 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000006006 250.0
HFD2_k127_3733314_2 chromosome segregation K03497 - - 0.0000000000000000000000000000000008075 141.0
HFD2_k127_3733314_3 Belongs to the UPF0312 family - - - 0.000000001379 60.0
HFD2_k127_3741655_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 364.0
HFD2_k127_3741655_1 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005099 281.0
HFD2_k127_3741935_0 WD domain, G-beta repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 517.0
HFD2_k127_3741935_1 Involved in initiation control of chromosome replication - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006785 416.0
HFD2_k127_3741935_2 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000221 284.0
HFD2_k127_3741935_3 Protein tyrosine kinase K11912 - 2.7.11.1 0.000000000000000000000000000000000000000000000002897 201.0
HFD2_k127_3741935_4 - - - - 0.000000002709 64.0
HFD2_k127_3741935_5 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000003857 61.0
HFD2_k127_3741935_6 PFAM Integrase, catalytic - - - 0.0000004119 54.0
HFD2_k127_3741935_7 PFAM IS1 transposase K07480 - - 0.000001265 51.0
HFD2_k127_3741935_8 nucleotidyltransferase activity - - - 0.000001833 53.0
HFD2_k127_374269_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1263.0
HFD2_k127_374269_1 isoprenoid biosynthetic process K13787,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000005293 225.0
HFD2_k127_374269_2 peptidase - - - 0.000000000000000000000000000000141 139.0
HFD2_k127_374269_3 Esterase-like activity of phytase - - - 0.0000000000000000393 87.0
HFD2_k127_374269_4 Putative regulatory protein - - - 0.00000000000001724 74.0
HFD2_k127_376108_0 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 370.0
HFD2_k127_376108_1 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000004793 156.0
HFD2_k127_376775_0 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 366.0
HFD2_k127_376775_1 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000001888 187.0
HFD2_k127_376775_2 cheY-homologous receiver domain - - - 0.000000000000000000000000002088 117.0
HFD2_k127_376775_3 Cellulose biosynthesis protein BcsQ K03496 - - 0.00001887 55.0
HFD2_k127_3778603_0 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007565 331.0
HFD2_k127_3778603_1 PFAM short-chain dehydrogenase reductase SDR K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000000000002599 194.0
HFD2_k127_3778603_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000002311 92.0
HFD2_k127_3778603_3 DinB superfamily - - - 0.000006483 55.0
HFD2_k127_3779266_0 Protein of unknown function (DUF2723) - - - 0.000000000000000000000002761 113.0
HFD2_k127_3781940_0 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007514 331.0
HFD2_k127_3781940_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 298.0
HFD2_k127_3781940_2 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002792 271.0
HFD2_k127_3781940_3 PFAM aminotransferase, class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000003555 234.0
HFD2_k127_378309_0 Glutamine synthetase N-terminal domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 539.0
HFD2_k127_378309_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 408.0
HFD2_k127_378884_0 acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000000000166 208.0
HFD2_k127_378884_1 phosphinothricin N-acetyltransferase activity K00604,K03825 GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 2.1.2.9 0.000000000000000000000000000000000000002085 158.0
HFD2_k127_378884_2 Protein of unknown function (DUF1706) - - - 0.0000168 47.0
HFD2_k127_378884_3 DinB superfamily - - - 0.0003034 52.0
HFD2_k127_378884_4 hydrolase activity, acting on ester bonds - - - 0.0003851 45.0
HFD2_k127_379506_0 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000766 371.0
HFD2_k127_379506_1 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000001009 239.0
HFD2_k127_3802491_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 474.0
HFD2_k127_3805246_0 Lanthionine synthetase C-like protein - - - 1.845e-260 837.0
HFD2_k127_3805246_1 NHLM bacteriocin system ABC transporter, ATP-binding protein K06148 - - 3.586e-227 723.0
HFD2_k127_3813826_0 Integrase catalytic - - - 0.00000000000000000000000002524 115.0
HFD2_k127_3813826_1 Recombinase - - - 0.00001285 58.0
HFD2_k127_3820431_0 Converts the aldose L-fucose into the corresponding ketose L-fuculose K01804 - 5.3.1.4 3.201e-204 645.0
HFD2_k127_3820431_1 transposition K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 414.0
HFD2_k127_3820431_10 Required for chromosome condensation and partitioning K03529 - - 0.0001677 48.0
HFD2_k127_3820431_2 import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006528 398.0
HFD2_k127_3820431_3 Branched-chain amino acid transport system / permease component K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002282 271.0
HFD2_k127_3820431_4 Branched-chain amino acid transport system / permease component K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000166 229.0
HFD2_k127_3820431_5 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000034 222.0
HFD2_k127_3820431_6 IclR helix-turn-helix domain K10439 - - 0.000000000000000000000000000000000000000000000000000009566 209.0
HFD2_k127_3820431_7 Pfam:DUF718 K03534 - 5.1.3.32 0.000000000000000000000000000000000000009912 147.0
HFD2_k127_3820431_8 transcriptional K22103 - - 0.000000000000000000000000007946 126.0
HFD2_k127_3820431_9 ABC transporter, ATP-binding protein K02003 - - 0.00000000000006611 76.0
HFD2_k127_3821679_0 aminotransferase class I and II K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 388.0
HFD2_k127_3821679_1 Sigma-70 region 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000003597 228.0
HFD2_k127_3821679_2 Putative zinc-finger - - - 0.0000000000000000002438 90.0
HFD2_k127_3825412_0 Glycyl-tRNA synthetase alpha subunit K14164 - 6.1.1.14 0.0 1074.0
HFD2_k127_3825412_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 4.546e-271 843.0
HFD2_k127_3825412_10 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000001187 187.0
HFD2_k127_3825412_11 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000007517 146.0
HFD2_k127_3825412_12 - - - - 0.0000000000000000000000000000000002859 139.0
HFD2_k127_3825412_13 Penicillinase repressor - - - 0.0000000000000000000000000000002377 127.0
HFD2_k127_3825412_14 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000412 118.0
HFD2_k127_3825412_15 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000003752 90.0
HFD2_k127_3825412_16 Extracellular solute-binding protein K02027 - - 0.0000003086 64.0
HFD2_k127_3825412_2 2-aminobenzoate-CoA ligase K08295 - 6.2.1.32 5.611e-221 698.0
HFD2_k127_3825412_3 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006769 534.0
HFD2_k127_3825412_4 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 508.0
HFD2_k127_3825412_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 404.0
HFD2_k127_3825412_6 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001298 232.0
HFD2_k127_3825412_7 2-keto-3-deoxy-L-rhamnonate aldolase activity K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000175 231.0
HFD2_k127_3825412_8 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000001467 218.0
HFD2_k127_3825412_9 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000000443 196.0
HFD2_k127_3825501_0 trisaccharide binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 417.0
HFD2_k127_3825501_1 COGs COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 325.0
HFD2_k127_3825501_2 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000003898 230.0
HFD2_k127_3825501_3 hydroperoxide reductase activity - - - 0.000000000000000000000000000000000000000000000000000000003344 204.0
HFD2_k127_3825501_4 - - - - 0.00000000000000000005793 91.0
HFD2_k127_3825501_5 Luciferase-like monooxygenase - - - 0.0000000000000003578 88.0
HFD2_k127_3837320_0 Carboxyl transferase domain - - - 1.597e-287 888.0
HFD2_k127_3837320_1 Pfam:CPSase_L_chain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009227 511.0
HFD2_k127_3837320_11 photosynthesis K02656 - - 0.000000000000003517 90.0
HFD2_k127_3837320_12 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000001155 77.0
HFD2_k127_3837320_13 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000001396 70.0
HFD2_k127_3837320_14 - - - - 0.0000002061 59.0
HFD2_k127_3837320_15 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.000008596 49.0
HFD2_k127_3837320_2 heat shock protein 70 K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 456.0
HFD2_k127_3837320_3 Belongs to the HpcH HpaI aldolase family K01644,K08691 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0009987,GO:0015977,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0043167,GO:0043169,GO:0043427,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046872,GO:0047777,GO:0050083,GO:0071704 4.1.3.24,4.1.3.25,4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008357 299.0
HFD2_k127_3837320_4 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004387 270.0
HFD2_k127_3837320_5 PFAM MaoC domain protein dehydratase K14449 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.0000000000000000000000000000000000000000000000000000000000000004421 224.0
HFD2_k127_3837320_6 PFAM biotin lipoyl attachment domain-containing protein - - - 0.00000000000000000000000000000000000000000000000001813 184.0
HFD2_k127_3837320_7 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000001144 169.0
HFD2_k127_3837320_8 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000004721 159.0
HFD2_k127_3837320_9 heat shock protein binding K03686,K05516 - - 0.000000000000000002454 89.0
HFD2_k127_384161_0 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008293 381.0
HFD2_k127_384161_1 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000001092 180.0
HFD2_k127_384161_2 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000004858 166.0
HFD2_k127_384161_3 Lysyl oxidase - - - 0.00000000000000000000000006361 124.0
HFD2_k127_384161_4 Transposase - - - 0.00000000000000001425 84.0
HFD2_k127_384161_5 - - - - 0.000000000008777 75.0
HFD2_k127_384161_6 Transposase IS66 family - - - 0.000006107 49.0
HFD2_k127_3843877_0 acetyltransferase - - - 0.0000000000000000000000000000000000000002851 162.0
HFD2_k127_3843877_1 acetyltransferase - - - 0.000000000000000000000000000000000003497 150.0
HFD2_k127_3843877_2 PFAM Nitroreductase - - - 0.0000000000000000000006756 101.0
HFD2_k127_3843877_3 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.00000000002268 68.0
HFD2_k127_3845549_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 427.0
HFD2_k127_3845549_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000007869 225.0
HFD2_k127_3845549_2 PFAM regulatory protein, MarR - - - 0.0000000000000000000000000009478 117.0
HFD2_k127_3849288_0 MacB-like periplasmic core domain K02004 - - 9.749e-218 706.0
HFD2_k127_3849288_1 hydrolase family 20, catalytic K12373 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 381.0
HFD2_k127_3849288_2 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001353 273.0
HFD2_k127_3849288_3 Histidine kinase K00936,K13924,K20962 - 2.1.1.80,2.7.13.3,3.1.1.61,3.1.4.52 0.0000008019 51.0
HFD2_k127_3858130_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 2.161e-200 638.0
HFD2_k127_386242_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006256 291.0
HFD2_k127_386242_1 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001127 254.0
HFD2_k127_386242_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000009767 216.0
HFD2_k127_386242_3 universal stress protein - - - 0.0000000000000000000000000000000000005849 152.0
HFD2_k127_386242_4 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000003117 109.0
HFD2_k127_386242_5 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000009648 94.0
HFD2_k127_386242_6 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352,K21307 - 1.8.5.5,1.8.5.6 0.000000000001977 67.0
HFD2_k127_386242_7 - - - - 0.0004444 48.0
HFD2_k127_386242_8 Psort location Cytoplasmic, score - - - 0.0005322 49.0
HFD2_k127_3862754_0 Spermine/spermidine synthase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 470.0
HFD2_k127_3862754_1 SMART Nucleotide binding protein, PINc - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 380.0
HFD2_k127_3862754_2 threonine efflux transmembrane transporter activity K11939 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 370.0
HFD2_k127_3862754_3 PFAM Transcription regulator, AsnC-type-like K03718 - - 0.00000000000000000000000000000000000000000000000000000000000000000001021 237.0
HFD2_k127_3862754_4 TIGRFAM integral membrane protein TIGR01906 - - - 0.000000000000000000000000000000000000000004695 163.0
HFD2_k127_3862754_5 PQQ enzyme repeat - - - 0.00000000000000000000000000000000000002857 150.0
HFD2_k127_3862754_6 PFAM peptidase - - - 0.0000000000000000000000000000002969 131.0
HFD2_k127_3862754_7 PFAM HD domain - - - 0.00000000000001696 81.0
HFD2_k127_3862754_8 prephenate dehydrogenase K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12 0.00000000003769 72.0
HFD2_k127_3863130_0 SPTR A9B8L4 Integrase catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 374.0
HFD2_k127_3863130_1 Integrase catalytic K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003916 267.0
HFD2_k127_3863130_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate - - - 0.0000000000000000000000000000000000000006794 154.0
HFD2_k127_3868947_0 Zn-dependent protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 322.0
HFD2_k127_3868947_1 PFAM Alpha beta hydrolase fold-3 domain protein K14731 - 3.1.1.83 0.00000000000000000000000000000005996 139.0
HFD2_k127_3870812_0 Beta-lactamase class C and other penicillin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 323.0
HFD2_k127_3870812_1 Fructosamine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001912 286.0
HFD2_k127_3870812_2 PFAM regulatory protein, MerR K22491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002044 284.0
HFD2_k127_3870812_3 Phosphoribosyl transferase domain K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000005104 253.0
HFD2_k127_3870812_4 PFAM LmbE family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001535 252.0
HFD2_k127_3881039_0 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 343.0
HFD2_k127_3881039_1 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 342.0
HFD2_k127_3881039_2 self proteolysis - - - 0.0000000000000000000000000000000000000009231 164.0
HFD2_k127_3881039_3 PFAM Transglutaminase-like superfamily K22452 - 2.3.2.13 0.00000000000000000000000000000001308 144.0
HFD2_k127_3881039_4 protein some members contain a von Willebrand factor type A vWA domain - - - 0.0000000000000000000000000005626 127.0
HFD2_k127_3890367_0 Helix-turn-helix domain of transposase family ISL3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 435.0
HFD2_k127_3890367_1 PFAM transposase IS204 IS1001 IS1096 IS1165 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000361 289.0
HFD2_k127_3890367_2 Transposase IS66 family K07484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 291.0
HFD2_k127_3890367_3 Phytoene dehydrogenase K15745 - 1.3.99.30 0.00000000000000000000000002141 112.0
HFD2_k127_3890367_4 zinc-finger binding domain of transposase IS66 K07484 - - 0.00000000000003236 77.0
HFD2_k127_3890367_5 Putative ATPase subunit of terminase (gpP-like) - - - 0.0000000000002065 76.0
HFD2_k127_3890367_6 PFAM Major Facilitator Superfamily - - - 0.000000001042 69.0
HFD2_k127_3890367_7 phytoene synthase K21678 - 2.5.1.103 0.000002541 59.0
HFD2_k127_3897765_0 Domain of unknown function (DUF5054) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 621.0
HFD2_k127_3897765_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005886 541.0
HFD2_k127_3897765_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 511.0
HFD2_k127_3897765_3 MBOAT, membrane-bound O-acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000001305 216.0
HFD2_k127_3897765_4 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000004049 143.0
HFD2_k127_3897765_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000001303 71.0
HFD2_k127_3898660_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 515.0
HFD2_k127_3898660_1 ATP hydrolysis coupled proton transport K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 327.0
HFD2_k127_3898660_2 ATP synthase subunit C K02124 - - 0.0000000000000004283 85.0
HFD2_k127_3898660_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000001003 84.0
HFD2_k127_3898660_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.00000000000001498 77.0
HFD2_k127_3898660_5 subunit (C K02119 - - 0.0003634 47.0
HFD2_k127_3900494_0 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 398.0
HFD2_k127_3900494_1 Putative metallopeptidase domain - - - 0.00000000000000000000000000005597 117.0
HFD2_k127_3900494_2 Protein of unknown function (DUF433) - - - 0.000000000000000004397 86.0
HFD2_k127_3900494_3 PBS lyase HEAT-like repeat - - - 0.0003805 54.0
HFD2_k127_3902021_0 PFAM ComEC Rec2-related protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 392.0
HFD2_k127_3902021_1 isomerase activity K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003633 275.0
HFD2_k127_3902021_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000004725 235.0
HFD2_k127_3902021_3 Glycosyl hydrolase family 20, domain 2 K12373 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000008747 225.0
HFD2_k127_3902021_4 PFAM OsmC family protein K06889,K07397 - - 0.000000000000000000000002281 108.0
HFD2_k127_3920630_0 ATP-dependent transcriptional regulator K03556 - - 2.67e-293 927.0
HFD2_k127_3920630_1 helix_turn_helix, Lux Regulon K03556 - - 8.9e-231 734.0
HFD2_k127_3920630_10 - - - - 0.00000000000000001622 87.0
HFD2_k127_3920630_11 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000003397 75.0
HFD2_k127_3920630_2 SMP-30 gluconolaconase LRE-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008099 383.0
HFD2_k127_3920630_3 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 366.0
HFD2_k127_3920630_4 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 343.0
HFD2_k127_3920630_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002767 273.0
HFD2_k127_3920630_6 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000004772 198.0
HFD2_k127_3920630_7 UTRA K03710,K11922 - - 0.000000000000000000000000000000000000000000000000004924 190.0
HFD2_k127_3920630_8 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000000000000000000000000008 186.0
HFD2_k127_3920630_9 transposition, DNA-mediated K02529,K20971 - - 0.0000000000000000000000001577 111.0
HFD2_k127_393548_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 315.0
HFD2_k127_393548_1 Mur ligase family, glutamate ligase domain K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 302.0
HFD2_k127_393548_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006004 254.0
HFD2_k127_393548_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000132 128.0
HFD2_k127_393548_4 Belongs to the UPF0109 family K06960 - - 0.000000000000000000007461 95.0
HFD2_k127_393548_5 Acetyltransferase (GNAT) domain K03817 - - 0.00000000000000003698 91.0
HFD2_k127_3936266_0 DNA/RNA non-specific endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 521.0
HFD2_k127_3936266_1 mandelate racemase muconate lactonizing K08323 - 4.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000078 449.0
HFD2_k127_3936266_2 glycerophosphodiester transmembrane transport K02026,K10119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 330.0
HFD2_k127_3936266_3 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000006799 212.0
HFD2_k127_3938981_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 345.0
HFD2_k127_3938981_1 PFAM Resolvase - - - 0.000000000000000000000000000000000000000000000000000000000000173 214.0
HFD2_k127_3945782_0 PFAM extracellular solute-binding protein family 1 K10117,K17315 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 530.0
HFD2_k127_3945782_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007939 361.0
HFD2_k127_3945782_2 Glyco_18 K06306 - - 0.000000000006937 77.0
HFD2_k127_3945782_3 Cysteine-rich secretory protein family - - - 0.0003775 52.0
HFD2_k127_3947877_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000001546 271.0
HFD2_k127_3947877_1 PFAM glycosyl transferase family 39 - - - 0.00000002252 66.0
HFD2_k127_3950192_0 modification enzyme, MiaB family K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 407.0
HFD2_k127_3950192_1 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000002435 238.0
HFD2_k127_3950192_2 Glycosyltransferases, probably involved in cell wall biogenesis K00694 - 2.4.1.12 0.000000000000000000000000000000000000000000000000000000000005739 234.0
HFD2_k127_3950192_3 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000001198 147.0
HFD2_k127_3950192_4 Glycoprotease family K14742 - - 0.000000000000000000000000000000000000774 148.0
HFD2_k127_3950192_5 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000006894 139.0
HFD2_k127_3957292_0 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000007235 270.0
HFD2_k127_3958725_0 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 507.0
HFD2_k127_3974161_0 ABC transporter K06147 - - 2.697e-256 810.0
HFD2_k127_3974161_1 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 579.0
HFD2_k127_3974161_2 PFAM regulatory protein TetR - - - 0.0000000000000000000002094 104.0
HFD2_k127_3974161_3 ABC transporter K06147 - - 0.0000000002832 65.0
HFD2_k127_3975068_0 Thermophilic metalloprotease (M29) K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 480.0
HFD2_k127_3975068_1 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000002759 196.0
HFD2_k127_3975068_2 Domain of unknown function (DUF4276) - - - 0.00000000000003989 79.0
HFD2_k127_3986437_0 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 529.0
HFD2_k127_3986437_1 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 469.0
HFD2_k127_3986437_2 Belongs to the arylamine N-acetyltransferase family - - - 0.00000000000000000000000000000000000000000000000004022 191.0
HFD2_k127_3986437_3 PFAM Chorismate mutase of the AroH class K06208 - 5.4.99.5 0.000000000000000000000000000000000000000000000004435 177.0
HFD2_k127_3986437_4 PFAM cyclic nucleotide-binding - - - 0.000000000000000000005206 99.0
HFD2_k127_3986437_5 - - - - 0.0000005461 53.0
HFD2_k127_3999624_0 response to antibiotic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006782 604.0
HFD2_k127_3999624_1 Capsule synthesis protein K07282 - - 0.0000000000000000000000000000000000000000000919 176.0
HFD2_k127_3999624_2 Phospholipid methyltransferase - - - 0.000000000002955 76.0
HFD2_k127_3999624_3 DUF35 OB-fold domain, acyl-CoA-associated K07068,K07549 - - 0.0000000408 59.0
HFD2_k127_3999624_4 antibiotic catabolic process - - - 0.0000001534 65.0
HFD2_k127_4000902_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006438 465.0
HFD2_k127_4000902_1 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 430.0
HFD2_k127_4000902_2 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 390.0
HFD2_k127_4000902_3 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006324 271.0
HFD2_k127_4007021_0 Aminotransferase class-V K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 352.0
HFD2_k127_4007021_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000001366 146.0
HFD2_k127_401701_0 ABC transporter permease K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 417.0
HFD2_k127_401701_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 357.0
HFD2_k127_401701_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 326.0
HFD2_k127_401701_3 ATPase activity K02052,K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 333.0
HFD2_k127_401701_4 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000001035 140.0
HFD2_k127_401701_5 B12 binding domain - - - 0.00002997 47.0
HFD2_k127_4018729_0 TIGRFAM dihydroxyacetone kinase, DhaK subunit K05878 - 2.7.1.121 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 545.0
HFD2_k127_4018729_1 TIGRFAM dihydroxyacetone kinase, L subunit K05879 - 2.7.1.121 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001438 276.0
HFD2_k127_40254_0 hydrolase, family 65, central catalytic K05342 - 2.4.1.64 1.123e-268 843.0
HFD2_k127_40254_1 Alpha amylase catalytic K01187,K05343 - 3.2.1.1,3.2.1.20,5.4.99.16 2.261e-213 675.0
HFD2_k127_40254_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 363.0
HFD2_k127_40254_3 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 293.0
HFD2_k127_40254_4 Isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000001119 208.0
HFD2_k127_4027461_0 Belongs to the thiolase family K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 508.0
HFD2_k127_4027461_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006735 486.0
HFD2_k127_4027461_2 3-hydroxyacyl-CoA dehydrogenase domain protein K07516 - 1.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 388.0
HFD2_k127_4027461_3 GyrI-like small molecule binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003236 238.0
HFD2_k127_4027461_4 PFAM extracellular solute-binding protein family 1 K02040 - - 0.00000000000000000000000000000000304 141.0
HFD2_k127_4027461_5 Predicted membrane protein (DUF2079) - - - 0.000000000000000000000000000004894 136.0
HFD2_k127_4027461_6 of ABC transporters with duplicated ATPase K06158 - - 0.0000000000000000004516 91.0
HFD2_k127_403097_0 Pyridoxal-dependent decarboxylase conserved domain - - - 8.435e-199 628.0
HFD2_k127_403097_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 - 6.1.1.16,6.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 433.0
HFD2_k127_403097_2 diacylglycerol kinase, catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000003139 237.0
HFD2_k127_403097_3 PFAM transferase hexapeptide repeat containing protein K04042 - 2.3.1.157,2.7.7.23 0.00000000000000001823 88.0
HFD2_k127_4030985_0 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 433.0
HFD2_k127_4030985_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 344.0
HFD2_k127_4030985_2 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 315.0
HFD2_k127_4030985_3 PEGA domain - - - 0.00003993 55.0
HFD2_k127_4031271_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005546 515.0
HFD2_k127_4031271_1 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000009163 185.0
HFD2_k127_4031271_2 helix_turn_helix, Lux Regulon - - - 0.000000000009657 66.0
HFD2_k127_4031858_0 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006888 376.0
HFD2_k127_4031858_1 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000003681 226.0
HFD2_k127_4031858_2 Rod shape-determining protein K03569 - - 0.0000002278 61.0
HFD2_k127_4037705_0 spore germination K03298 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005171 247.0
HFD2_k127_4037705_1 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0000000000000000000000000000000000000000000000000000002387 219.0
HFD2_k127_4037705_2 P-type ATPase K01537 - 3.6.3.8 0.000000000003812 74.0
HFD2_k127_4037705_3 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.000000000189 70.0
HFD2_k127_4037705_4 PFAM SH3 type 3 domain protein - - - 0.00000006451 66.0
HFD2_k127_4039947_0 proteolysis K07059 - - 0.000000000000000000000000000000000000000000000000000000000007648 214.0
HFD2_k127_4039947_1 PFAM Glycosyl transferase, group 1 K03525 - 2.7.1.33 0.00000000000000000000000373 108.0
HFD2_k127_4043537_0 Membrane - - - 0.000000000000000000000000000000000000000000000000000000006346 203.0
HFD2_k127_4043537_1 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000001932 177.0
HFD2_k127_4043537_2 PFAM response regulator receiver K03413 - - 0.000000000001562 70.0
HFD2_k127_4044605_0 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000561 274.0
HFD2_k127_4044605_1 COG0411 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000005774 239.0
HFD2_k127_4044605_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000001719 209.0
HFD2_k127_4044605_3 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000003391 190.0
HFD2_k127_4049711_0 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000000000000000000838 145.0
HFD2_k127_4049711_1 NUDIX domain - - - 0.000000000000000000000000000000000002094 146.0
HFD2_k127_4049711_2 Virulence activator alpha C-term - - - 0.000000000002406 75.0
HFD2_k127_4050172_0 56kDa selenium binding protein (SBP56) - - - 2.463e-257 800.0
HFD2_k127_4050172_1 transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 563.0
HFD2_k127_4050172_2 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000001151 159.0
HFD2_k127_4054610_0 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K08070 - 1.3.1.74,3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003401 287.0
HFD2_k127_4054610_1 Dihydrodipicolinate reductase, N-terminus K00150 - 1.2.1.59 0.0000000000000000000000000000000000000000002578 162.0
HFD2_k127_4054610_2 monooxygenase activity - - - 0.000000004215 63.0
HFD2_k127_4063824_0 ROK family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001125 239.0
HFD2_k127_4063824_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.000000000002652 79.0
HFD2_k127_4064142_0 protein conserved in bacteria - - - 0.00003669 57.0
HFD2_k127_4064142_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0008146 43.0
HFD2_k127_4064246_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004614 460.0
HFD2_k127_4064246_1 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 347.0
HFD2_k127_4064246_2 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000004611 130.0
HFD2_k127_4064246_3 PFAM ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000255 120.0
HFD2_k127_4064246_4 DNA-binding transcriptional activator of the SARP family - - - 0.00001802 59.0
HFD2_k127_4065719_0 SAF K01654 - 2.5.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 530.0
HFD2_k127_4065719_1 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 472.0
HFD2_k127_4065719_2 transferase activity, transferring hexosyl groups K15897 - 3.6.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005038 354.0
HFD2_k127_4065719_3 Peptidase M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 366.0
HFD2_k127_4065719_4 Formyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 301.0
HFD2_k127_4065719_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000004322 234.0
HFD2_k127_4065719_6 Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase K01845,K07257 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000005506 221.0
HFD2_k127_4065719_7 PFAM acylneuraminate cytidylyltransferase K00983 - 2.7.7.43 0.0000000000000000000000000000000000001519 151.0
HFD2_k127_4065719_8 Updated (2006) note Literature search identified paper linking product function of Cj1296 Cj1297 Cj1298 to antimicrobial efflux pumps K00662 - 2.3.1.81 0.0000000000000000000000001146 124.0
HFD2_k127_4065719_9 Polysaccharide pyruvyl transferase - - - 0.000000000007444 70.0
HFD2_k127_4067539_0 PFAM ADP-ribosylation Crystallin J1 - - - 7.46e-297 925.0
HFD2_k127_4067539_1 carbohydrate transport K10117 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 484.0
HFD2_k127_4067539_2 glycerophosphodiester transmembrane transport K10119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 379.0
HFD2_k127_4067539_3 transmembrane transport K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 369.0
HFD2_k127_4067539_4 purine nucleotide biosynthetic process K02529 - - 0.00000000000000000000000000000000000000000000000000000000002839 211.0
HFD2_k127_4067539_5 Acetyltransferase GNAT family - - - 0.00002336 54.0
HFD2_k127_4076574_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.21e-205 656.0
HFD2_k127_4076574_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00113 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009814 363.0
HFD2_k127_4076574_2 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006479 307.0
HFD2_k127_4076574_3 Thermophilic metalloprotease (M29) K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008819 284.0
HFD2_k127_4076574_4 SCO1/SenC K03619,K07152 GO:0003674,GO:0005048,GO:0005488,GO:0033218,GO:0042277 - 0.000000000000000000000000000000000000000002332 166.0
HFD2_k127_4076574_5 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000005573 146.0
HFD2_k127_4076574_6 Isochorismatase family K08281 - 3.5.1.19 0.0000000003459 68.0
HFD2_k127_4076574_7 Protein of unknown function (DUF1572) - - - 0.0000000005132 65.0
HFD2_k127_4076913_0 Catalyzes the transfer of the amino group of L-glutamate to LysW -aminoadipate 6-semialdehyde, generating LysW -gamma-L- lysine K05830 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 493.0
HFD2_k127_4076913_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649,K02594 - 2.3.3.13,2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 479.0
HFD2_k127_4076913_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K16792 - 4.2.1.114,4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 373.0
HFD2_k127_4078580_0 nUDIX hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000003412 231.0
HFD2_k127_4078580_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 0.000000000000000001086 88.0
HFD2_k127_4079435_0 FAD linked oxidases, C-terminal domain - - - 7.501e-201 646.0
HFD2_k127_4081556_0 SMART AAA ATPase K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 322.0
HFD2_k127_4081556_1 PFAM thioesterase superfamily protein - - - 0.000000000000000000000000000000000000000000005247 168.0
HFD2_k127_4085931_0 alcohol dehydrogenase K00008,K05351 - 1.1.1.14,1.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 569.0
HFD2_k127_4085931_1 transmembrane transport K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17242,K17316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 421.0
HFD2_k127_4085931_2 COG1653 ABC-type sugar transport system, periplasmic component K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 388.0
HFD2_k127_4085931_3 COG0395 ABC-type sugar transport system permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 387.0
HFD2_k127_4085931_4 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 378.0
HFD2_k127_4085931_5 Predicted small integral membrane protein (DUF2160) - - - 0.000000000005079 68.0
HFD2_k127_4087621_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1371.0
HFD2_k127_4087621_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008087 267.0
HFD2_k127_4087621_2 Helix-turn-helix type 11 domain protein - - - 0.0000000000000000000000000000000000000000000001218 172.0
HFD2_k127_4087621_3 DinB family - - - 0.000000000000000000000000000000000000000000001573 169.0
HFD2_k127_4099438_0 SPTR A9B8L4 Integrase catalytic region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004312 265.0
HFD2_k127_4099438_1 Protein of unknown function (DUF1304) K08987 - - 0.000000000000000000000000000000000000006119 148.0
HFD2_k127_4099438_2 transposition K07497 - - 0.00000000000000003609 85.0
HFD2_k127_4099438_3 - - - - 0.0000000000000003083 81.0
HFD2_k127_4099438_4 aldo keto reductase - - - 0.00000004277 57.0
HFD2_k127_4099438_5 aldo keto reductase - - - 0.0000001715 53.0
HFD2_k127_4099438_6 Aldo/keto reductase family - - - 0.0000002234 52.0
HFD2_k127_4099438_7 transposition K07497 - - 0.000002219 50.0
HFD2_k127_4109585_0 DEAD-like helicases superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001884 291.0
HFD2_k127_4109585_1 Phosphoadenosine phosphosulfate reductase family - - - 0.0000000000002929 73.0
HFD2_k127_4109585_2 Domain of unknown function (DUF927) - - - 0.00000009483 63.0
HFD2_k127_4109855_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667,K01668 - 4.1.99.1,4.1.99.2 1.643e-238 744.0
HFD2_k127_4109855_1 ATPase activity K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 366.0
HFD2_k127_4109855_2 ATPase-coupled sulfate transmembrane transporter activity K02046,K02047 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008554 325.0
HFD2_k127_4109855_3 ATPase-coupled sulfate transmembrane transporter activity K02047 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000004292 237.0
HFD2_k127_4109855_4 PFAM short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000002154 184.0
HFD2_k127_4109855_5 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000001919 134.0
HFD2_k127_4109855_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000006385 90.0
HFD2_k127_4109855_7 extracellular solute-binding protein, family 1 K02027 - - 0.0000000001793 72.0
HFD2_k127_4112789_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.19e-285 920.0
HFD2_k127_4112789_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000298 161.0
HFD2_k127_4115457_0 PFAM Glyoxalase bleomycin resistance protein dioxygenase K15975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003499 350.0
HFD2_k127_4115457_1 IMG reference gene - - - 0.00000000165 66.0
HFD2_k127_4115654_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 504.0
HFD2_k127_4115654_1 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 314.0
HFD2_k127_4115654_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000006972 232.0
HFD2_k127_4115654_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000002379 76.0
HFD2_k127_4115654_4 Cell Wall K01448 - 3.5.1.28 0.0000006748 61.0
HFD2_k127_4115654_5 Domain of unknown function (DUF4397) - - - 0.0005347 53.0
HFD2_k127_412381_0 Family 4 glycosyl hydrolase K01222 - 3.2.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 432.0
HFD2_k127_412381_1 pfkB family carbohydrate kinase - - - 0.0000000000000000000537 93.0
HFD2_k127_412381_2 negative regulation of transcription, DNA-templated - - - 0.0000000000000007623 86.0
HFD2_k127_412381_3 heme binding K21472 - - 0.000000001481 60.0
HFD2_k127_4124053_0 Glycoside hydrolase family 16 - - - 1.639e-200 652.0
HFD2_k127_4124053_1 mandelate racemase K18334 - 4.2.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 578.0
HFD2_k127_4124053_2 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001956 254.0
HFD2_k127_4124053_3 Aldo/keto reductase family K06607 - - 0.00000000000000000000000000000000000000000000000000000000000000003774 233.0
HFD2_k127_4124053_4 PFAM Mandelate racemase muconate lactonizing enzyme K01683,K01684,K08323 GO:0000287,GO:0003674,GO:0005488,GO:0043167,GO:0043169,GO:0046872 4.2.1.5,4.2.1.6,4.2.1.8 0.00000000000000000000000000000000000000000000000000000002585 199.0
HFD2_k127_4124053_6 PFAM Methyltransferase type 12 - - - 0.000000000008733 70.0
HFD2_k127_4127495_0 PFAM ABC transporter related K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009682 321.0
HFD2_k127_4127495_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000821 314.0
HFD2_k127_4127495_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002242 267.0
HFD2_k127_4127495_3 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000001671 103.0
HFD2_k127_4127495_4 Von Willebrand factor type A K07114 - - 0.000000000001182 70.0
HFD2_k127_4130689_0 thiolester hydrolase activity K06889 - - 6.286e-197 630.0
HFD2_k127_4130689_1 Heparinase II/III-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 514.0
HFD2_k127_4130689_2 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 487.0
HFD2_k127_4130689_3 Glycosyltransferase family 28 N-terminal domain K05841 - 2.4.1.173 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 361.0
HFD2_k127_4130689_4 Domain of unknown function (DUF3471) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009023 267.0
HFD2_k127_4130689_5 PFAM Alpha beta hydrolase fold-3 domain protein K14731 - 3.1.1.83 0.0000000000000000000000000000000000000000000000000000000000514 217.0
HFD2_k127_4130689_6 Psort location Cytoplasmic, score 8.87 - - - 0.00009548 53.0
HFD2_k127_4133144_0 Putative peptidoglycan binding domain - - - 0.000000001479 68.0
HFD2_k127_4133144_1 Fibronectin type III domain - - - 0.000005777 57.0
HFD2_k127_4133998_0 hydrolase activity, hydrolyzing O-glycosyl compounds K01176,K01187 - 3.2.1.1,3.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 407.0
HFD2_k127_4135262_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 470.0
HFD2_k127_4135262_1 acetamidase formamidase K01455 - 3.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 400.0
HFD2_k127_4135262_2 Amidohydrolase family K01464,K01466 - 3.5.2.2,3.5.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 363.0
HFD2_k127_4135845_0 Peptidase S9, prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007217 308.0
HFD2_k127_4135845_1 Binding-protein-dependent transport system inner membrane component K02033,K13890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 298.0
HFD2_k127_4135845_2 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 295.0
HFD2_k127_4135845_3 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007556 289.0
HFD2_k127_4135845_4 LmbE homologs - - - 0.0000000000000134 76.0
HFD2_k127_414899_0 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.0 3422.0
HFD2_k127_4154150_0 PFAM NAD-dependent epimerase dehydratase K06118 - 3.13.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 580.0
HFD2_k127_4154150_1 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.000000000000000000000000000000000000000002765 169.0
HFD2_k127_4154150_2 MazG-like family - - - 0.0000000000000000000000000000000005787 133.0
HFD2_k127_4154150_3 Protein of unknown function (DUF1706) - - - 0.0000000000000001229 92.0
HFD2_k127_4154150_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000002332 52.0
HFD2_k127_4158578_0 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441,K10562,K17215 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 503.0
HFD2_k127_4158578_1 Immune inhibitor A peptidase M6 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 441.0
HFD2_k127_4158578_2 PFAM periplasmic binding protein LacI transcriptional regulator K02058,K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008045 344.0
HFD2_k127_4158578_3 Immune inhibitor A peptidase M6 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 335.0
HFD2_k127_4158578_4 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000159 216.0
HFD2_k127_4158578_5 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000002254 154.0
HFD2_k127_4158578_6 Branched-chain amino acid transport system / permease component K10440 - - 0.00000000000000000000000000114 120.0
HFD2_k127_4158578_7 Protein of unknown function (DUF1232) - - - 0.0004153 49.0
HFD2_k127_4164124_0 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 370.0
HFD2_k127_4164124_1 Belongs to the D-alanine--D-alanine ligase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 354.0
HFD2_k127_4164124_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000009273 248.0
HFD2_k127_4164124_3 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000007745 126.0
HFD2_k127_4164124_4 Squalene-hopene cyclase C-terminal domain K17811 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009267,GO:0009605,GO:0009607,GO:0009975,GO:0009987,GO:0009991,GO:0010350,GO:0016101,GO:0016102,GO:0016114,GO:0016853,GO:0016872,GO:0019637,GO:0031667,GO:0031668,GO:0031669,GO:0033385,GO:0033554,GO:0035439,GO:0035440,GO:0042594,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071496,GO:0071704,GO:0075136,GO:1901576 5.5.1.16 0.0000000000000000001506 103.0
HFD2_k127_4164124_5 Putative transposase of IS4/5 family (DUF4096) - - - 0.0005491 44.0
HFD2_k127_4164852_0 PFAM von Willebrand factor type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009905 550.0
HFD2_k127_4164852_1 Aerotolerance regulator N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 364.0
HFD2_k127_4164852_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000009382 79.0
HFD2_k127_41697_0 serine-type endopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 359.0
HFD2_k127_41697_1 transposition, DNA-mediated K02529,K20971 - - 0.0000000000000000000000000000000000000000000000002935 189.0
HFD2_k127_41697_2 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000003975 180.0
HFD2_k127_41697_3 Methyltransferase domain - - - 0.000000000000000000000000000000008191 131.0
HFD2_k127_41697_4 transposition, DNA-mediated K02529,K20971 - - 0.000000000000000000106 94.0
HFD2_k127_41697_5 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000143 89.0
HFD2_k127_41697_6 Transposase IS66 family K07484 - - 0.0000000000009162 72.0
HFD2_k127_41697_7 Transposase - - - 0.0000007452 50.0
HFD2_k127_4170333_0 Belongs to the SEDS family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 336.0
HFD2_k127_4170333_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 327.0
HFD2_k127_4170333_2 Cell division protein FtsI penicillin-binding protein K05364 - - 0.0000000000000000000000000000000000000000000000004514 196.0
HFD2_k127_4170333_3 PFAM Forkhead-associated protein - - - 0.000000000000000000000000000000005483 139.0
HFD2_k127_4170333_4 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000007984 113.0
HFD2_k127_4170333_5 PFAM Forkhead-associated protein - - - 0.000000000000000000000002465 107.0
HFD2_k127_4170333_6 XisH protein - - - 0.00000000000000000000001317 104.0
HFD2_k127_4170337_0 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 1.757e-278 886.0
HFD2_k127_4170337_1 carbohydrate transport - - - 0.000000000000000000000000000000000000000000000000000000009787 214.0
HFD2_k127_4174526_0 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 406.0
HFD2_k127_4174526_1 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 322.0
HFD2_k127_4174526_2 ABC transporter K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001643 278.0
HFD2_k127_4182158_0 PFAM NMT1 THI5 like domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 329.0
HFD2_k127_4182158_1 O-methyltransferase K00588 - 2.1.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 319.0
HFD2_k127_4182158_2 histidine biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 304.0
HFD2_k127_4182158_3 PFAM binding-protein-dependent transport systems inner membrane component K02050,K15599 - - 0.0000000000000000000000000000000000000000000000000000000001518 209.0
HFD2_k127_4182158_4 translation initiation factor activity - - - 0.000000000000000000000007471 105.0
HFD2_k127_4182158_5 COGs COG0463 Glycosyltransferase involved in cell wall biogenesis K20534 - - 0.000000000006335 66.0
HFD2_k127_4183453_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 486.0
HFD2_k127_4183453_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 296.0
HFD2_k127_4183754_0 carbohydrate transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 447.0
HFD2_k127_4183754_1 Belongs to the glycosyl hydrolase 32 family K03332 GO:0003674,GO:0003824,GO:0004553,GO:0004564,GO:0005975,GO:0005984,GO:0005985,GO:0005987,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016052,GO:0016787,GO:0016798,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0071704,GO:1901575 3.2.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 446.0
HFD2_k127_4183754_2 transmembrane transport K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 336.0
HFD2_k127_4183754_3 glycerophosphodiester transmembrane transport K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 325.0
HFD2_k127_4183754_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 304.0
HFD2_k127_4183754_5 Belongs to the glycosyl hydrolase 32 family K01193 - 3.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000005549 263.0
HFD2_k127_4183754_6 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000008737 159.0
HFD2_k127_4183754_7 PIN domain K07064 - - 0.0000000000000000000441 94.0
HFD2_k127_4183754_8 HNH endonuclease K07451 - - 0.00000000000000001334 87.0
HFD2_k127_4184070_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007494 454.0
HFD2_k127_4184070_1 ABC-type sugar transport system periplasmic component K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004512 256.0
HFD2_k127_4184070_2 DeoR C terminal sensor domain K02081 - - 0.000000000000000000000183 100.0
HFD2_k127_4184070_3 - - - - 0.000000000000003817 90.0
HFD2_k127_4190452_0 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 374.0
HFD2_k127_4190452_1 Mut7-C ubiquitin K09122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 312.0
HFD2_k127_4190452_10 Domain of unknown function (DUF4115) - - - 0.000000000000000000000002099 117.0
HFD2_k127_4190452_11 Acetyltransferase (GNAT) family - - - 0.00000000000004009 82.0
HFD2_k127_4190452_12 LysM domain K03642,K03791,K22278 - 3.5.1.104 0.0001064 52.0
HFD2_k127_4190452_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 303.0
HFD2_k127_4190452_3 NAD binding K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000963 272.0
HFD2_k127_4190452_4 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000001658 258.0
HFD2_k127_4190452_5 PASTA K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000005777 236.0
HFD2_k127_4190452_6 Protein of unknown function (DUF554) K07150 - - 0.00000000000000000000000000000000000000000000000000000001426 207.0
HFD2_k127_4190452_7 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000011 181.0
HFD2_k127_4190452_8 ribonuclease BN K07058 - - 0.000000000000000000000000000000001697 138.0
HFD2_k127_4190452_9 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000001877 122.0
HFD2_k127_4199758_0 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000002263 228.0
HFD2_k127_4199758_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000001475 145.0
HFD2_k127_4199758_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000006931 81.0
HFD2_k127_4199758_3 sh3 domain protein K01448,K04771,K08884 - 2.7.11.1,3.4.21.107,3.5.1.28 0.0000004329 61.0
HFD2_k127_4215433_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 4.161e-307 1015.0
HFD2_k127_4215433_1 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 545.0
HFD2_k127_4215433_2 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 323.0
HFD2_k127_4215433_3 Domain of unknown function (DUF1980) - - - 0.0000000000000000000000000000000000000000005346 166.0
HFD2_k127_4215433_4 beta-glucosidase - - - 0.00000000000000000000000000003762 130.0
HFD2_k127_4215433_5 Histidine kinase - - - 0.0000000000000000001528 90.0
HFD2_k127_4222872_0 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 463.0
HFD2_k127_4222872_1 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 292.0
HFD2_k127_4222872_2 Oxidoreductase family, NAD-binding Rossmann fold - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009987,GO:0016491,GO:0019362,GO:0019637,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:1901360,GO:1901564 - 0.00000000000000000000000000000000000000000000000000161 196.0
HFD2_k127_4222872_3 PFAM Maf family protein K06287 - - 0.00000000000000000000000000000000000000000003224 168.0
HFD2_k127_4222872_4 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.00000000000000000000000000000000000000007696 159.0
HFD2_k127_4225780_0 Belongs to the 3-oxoacid CoA-transferase family K01027 - 2.8.3.5 5.876e-230 718.0
HFD2_k127_4225780_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 2.782e-203 639.0
HFD2_k127_4225780_2 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 580.0
HFD2_k127_4225780_3 Adenylosuccinate lyase C-terminus K01857 - 5.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 491.0
HFD2_k127_4225780_4 Protocatechuate 3,4-dioxygenase beta subunit N terminal K00449 - 1.13.11.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 342.0
HFD2_k127_4225780_5 alpha beta hydrolase superfamily K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000002091 271.0
HFD2_k127_4225780_6 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001649 269.0
HFD2_k127_4225780_7 Dioxygenase K00448 - 1.13.11.3 0.00000000000000000000000000000000000000000000000000000001176 208.0
HFD2_k127_4225780_8 peroxiredoxin activity K01055,K01607,K14727 - 3.1.1.24,4.1.1.44 0.0000000000000000000000000000000000000000000000008552 178.0
HFD2_k127_4225780_9 TIGRFAM competence protein ComEA helix-hairpin-helix K02237 - - 0.000000000000000000000000000000008756 134.0
HFD2_k127_4226823_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1097.0
HFD2_k127_4226823_2 PFAM FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000008051 109.0
HFD2_k127_4226823_3 transposase activity - - - 0.00000001552 62.0
HFD2_k127_4227239_0 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003566 256.0
HFD2_k127_4227239_1 PFAM extracellular solute-binding protein, family 5 K15580 - - 0.00000000000000000000000000000000000000000000000000000001189 219.0
HFD2_k127_4227239_2 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000001863 154.0
HFD2_k127_4227239_3 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00041 49.0
HFD2_k127_4228528_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004311 266.0
HFD2_k127_4228528_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000004005 149.0
HFD2_k127_4233702_0 pfam abc K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008638 348.0
HFD2_k127_4233702_1 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006229 337.0
HFD2_k127_4233702_10 metal-dependent protease of the PAD1 JAB1 superfamily K20110 - 3.4.19.15 0.00000000000000000001788 96.0
HFD2_k127_4233702_11 Orotidine-5-phosphate decarboxylase orotate phosphoribosyltransferase K01591,K13421 - 2.4.2.10,4.1.1.23 0.000000003203 65.0
HFD2_k127_4233702_12 Belongs to the OMP decarboxylase family. Type 2 subfamily - - - 0.000000009624 66.0
HFD2_k127_4233702_13 Type II secretory pathway, prepilin signal peptidase PulO and related K02654 - 3.4.23.43 0.0000007223 61.0
HFD2_k127_4233702_2 PFAM molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005831 289.0
HFD2_k127_4233702_3 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003648 273.0
HFD2_k127_4233702_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001751 270.0
HFD2_k127_4233702_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.000000000000000000000000000000000000000000000000000000000003956 214.0
HFD2_k127_4233702_6 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000009912 205.0
HFD2_k127_4233702_7 protein histidine kinase activity K03407,K07678 - 2.7.13.3 0.00000000000000000000000000000000000000000607 160.0
HFD2_k127_4233702_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000004526 160.0
HFD2_k127_4233702_9 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997,K18014 - 2.7.8.7,4.3.1.14 0.000000000000000000000000000006624 122.0
HFD2_k127_4245938_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 542.0
HFD2_k127_4245938_1 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000001365 248.0
HFD2_k127_4249768_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008136 266.0
HFD2_k127_4249768_1 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000002484 191.0
HFD2_k127_4249768_2 Bacterial regulatory proteins, tetR family - - - 0.00000000007926 72.0
HFD2_k127_4250761_0 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 1.464e-269 862.0
HFD2_k127_4250761_1 chitin catabolic process K01183,K03933,K13381 GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005623,GO:0008843,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.2.1.14,3.2.1.17 0.0000000000000000000000000000000000000000004765 175.0
HFD2_k127_425837_0 Amino acid permease - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 6.304e-195 627.0
HFD2_k127_4258717_0 SMART AAA ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 542.0
HFD2_k127_4258717_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 526.0
HFD2_k127_4258717_2 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008785 323.0
HFD2_k127_4258717_3 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000001528 186.0
HFD2_k127_4258717_4 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.00000000000000000000000000000000000000000002347 169.0
HFD2_k127_4258717_5 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000001699 167.0
HFD2_k127_4258717_6 THIoesterase K18700 - 3.1.2.29 0.000000000000000000000000000000000006077 140.0
HFD2_k127_4258717_7 Putative small multi-drug export protein - - - 0.00000000000000000001111 97.0
HFD2_k127_4260438_0 PFAM NMT1 THI5 like domain protein K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005233 284.0
HFD2_k127_4260438_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000001093 190.0
HFD2_k127_4260438_2 Bacterial periplasmic substrate-binding proteins - - - 0.0000000000000000000000000000003171 140.0
HFD2_k127_4265534_0 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 379.0
HFD2_k127_4265534_1 PFAM CAAX amino terminal protease family - - - 0.00000000000000000000000000000000000000000000000000000001463 208.0
HFD2_k127_4265534_2 Short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000005087 183.0
HFD2_k127_4265534_3 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000003015 176.0
HFD2_k127_4265534_4 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000019 127.0
HFD2_k127_4265534_5 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0000785,GO:0003674,GO:0003676,GO:0003682,GO:0003723,GO:0003729,GO:0003824,GO:0003938,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030447,GO:0031347,GO:0031349,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0035690,GO:0035821,GO:0036170,GO:0036180,GO:0040007,GO:0042221,GO:0042278,GO:0042451,GO:0042455,GO:0042493,GO:0042594,GO:0043207,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044003,GO:0044182,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044403,GO:0044416,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0048518,GO:0048583,GO:0048584,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052251,GO:0052255,GO:0052509,GO:0052510,GO:0055086,GO:0055114,GO:0065007,GO:0070887,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0075136,GO:0080134,GO:0090407,GO:0097159,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 0.00004502 56.0
HFD2_k127_4265673_0 transposition - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004409 267.0
HFD2_k127_4265673_1 Transposase - - - 0.00000000000000000000002723 102.0
HFD2_k127_4265673_2 Alpha/beta hydrolase family - - - 0.0000000000000000000002068 104.0
HFD2_k127_4265673_3 Sulfatase-modifying factor enzyme 1 - - - 0.0002177 44.0
HFD2_k127_4265727_0 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 512.0
HFD2_k127_4265727_1 PFAM Glycosyl transferase family 2 K16557 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 325.0
HFD2_k127_4265727_2 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000001823 205.0
HFD2_k127_4265727_3 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000002165 181.0
HFD2_k127_4265727_4 Group 1 family - - - 0.0000000000000000000000000000000000000000000003673 181.0
HFD2_k127_4265727_5 Glycosyltransferase like family 2 - - - 0.00000000000002046 82.0
HFD2_k127_4267590_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 480.0
HFD2_k127_4267590_1 PFAM ABC transporter related K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000005785 230.0
HFD2_k127_4267590_2 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.0000000000000000000000000000000000000000000000000007058 190.0
HFD2_k127_4267590_3 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000002796 120.0
HFD2_k127_4267590_4 Cytochrome c - - - 0.00000000000002862 85.0
HFD2_k127_4267590_5 Transcriptional regulator PadR-like family - - - 0.0000000001206 70.0
HFD2_k127_4270965_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.166e-300 935.0
HFD2_k127_4270965_1 GHMP kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009203 469.0
HFD2_k127_4270965_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000002323 185.0
HFD2_k127_4270965_3 GrpB protein - - - 0.00000000000000000000000000000000000000004385 158.0
HFD2_k127_4270965_4 LysM domain - - - 0.000001205 61.0
HFD2_k127_4274359_0 PFAM ABC transporter related K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 484.0
HFD2_k127_4274359_1 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 327.0
HFD2_k127_4274359_2 Pfam:DUF2029 - - - 0.00003043 56.0
HFD2_k127_4275213_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 543.0
HFD2_k127_4275213_1 Transporter associated domain K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003773 283.0
HFD2_k127_4275213_2 LysM domain K06194 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - 0.000006235 58.0
HFD2_k127_4284724_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000919 203.0
HFD2_k127_4284724_1 helix_turn_helix, Lux Regulon - - - 0.00000001037 59.0
HFD2_k127_4289098_0 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000009359 110.0
HFD2_k127_4289098_1 Peptidase family M23 K21471 - - 0.0000000000000000001215 102.0
HFD2_k127_4290857_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 456.0
HFD2_k127_4290857_1 PFAM transposase, IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004917 280.0
HFD2_k127_4290857_2 transposase activity K07495 - - 0.00000000000000000000000000000000000000000000000000000000000135 215.0
HFD2_k127_4290857_3 EamA-like transporter family - - - 0.00000000000000000000000000000000001282 150.0
HFD2_k127_4290857_4 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.000000000000000000000000000001387 132.0
HFD2_k127_4290857_5 Belongs to the phosphoglycerate mutase family - - - 0.00000000000000000001728 99.0
HFD2_k127_4296344_0 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 499.0
HFD2_k127_4296344_1 Methyltransferase domain - - - 0.000000000000000000000000000000005637 132.0
HFD2_k127_43001_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 1.42e-235 760.0
HFD2_k127_43001_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 406.0
HFD2_k127_43001_10 lipolytic protein G-D-S-L family K18650 - 3.2.1.82 0.0001284 54.0
HFD2_k127_43001_11 Psort location CytoplasmicMembrane, score K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.000287 54.0
HFD2_k127_43001_2 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003628 268.0
HFD2_k127_43001_3 sh3 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000214 240.0
HFD2_k127_43001_4 Binding-protein-dependent transport system inner membrane component K02034,K13891 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000004108 208.0
HFD2_k127_43001_5 TAP-like protein - - - 0.00000000000000000000000000004468 128.0
HFD2_k127_43001_6 pyridoxamine 5'-phosphate K07005 - - 0.00000000000001533 76.0
HFD2_k127_43001_7 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000003332 68.0
HFD2_k127_43001_8 amine dehydrogenase activity - - - 0.000000004443 70.0
HFD2_k127_43001_9 Belongs to the glycosyl hydrolase 18 family - - - 0.000000009756 68.0
HFD2_k127_430160_0 ABC transporter transmembrane region K02021,K06147 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - 7.339e-282 879.0
HFD2_k127_430160_1 PFAM ABC transporter transmembrane region K06147 - - 2.581e-248 774.0
HFD2_k127_430160_2 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 516.0
HFD2_k127_430160_3 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 330.0
HFD2_k127_430160_4 heme binding K21472 - - 0.000007471 57.0
HFD2_k127_4301924_0 F5/8 type C domain - - - 0.0 1043.0
HFD2_k127_4301924_1 - - - - 1.211e-264 828.0
HFD2_k127_4301924_2 Beta-1,3-glucanase - - - 0.0000000000000000000000000000000000000000000000000000000000002818 218.0
HFD2_k127_430660_0 glycosyl hydrolase 38 domain protein K01191 - 3.2.1.24 0.0 1138.0
HFD2_k127_430660_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 4.88e-227 717.0
HFD2_k127_430660_10 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004335 295.0
HFD2_k127_430660_2 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 487.0
HFD2_k127_430660_3 COGs COG0601 ABC-type dipeptide oligopeptide nickel transport systems permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 473.0
HFD2_k127_430660_4 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 473.0
HFD2_k127_430660_5 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 393.0
HFD2_k127_430660_6 Periplasmic binding protein LacI transcriptional regulator K02103,K05499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008099 391.0
HFD2_k127_430660_7 Alpha mannosidase, middle domain K01191 - 3.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 408.0
HFD2_k127_430660_8 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 379.0
HFD2_k127_430660_9 dioxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 323.0
HFD2_k127_4310738_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 6.582e-307 948.0
HFD2_k127_4310738_1 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162,K11381 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008382 505.0
HFD2_k127_4310738_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 464.0
HFD2_k127_4310738_3 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 439.0
HFD2_k127_4310738_4 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000000000003326 181.0
HFD2_k127_4310738_5 Phosphopantetheine attachment site - - - 0.000000000000000002889 92.0
HFD2_k127_4343837_0 Xaa-Pro aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009282 531.0
HFD2_k127_4343837_1 PFAM Acetamidase Formamidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 396.0
HFD2_k127_4343837_2 cyclic nucleotide binding K01420,K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007407 283.0
HFD2_k127_4343837_3 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000001056 183.0
HFD2_k127_4343837_4 - - - - 0.000000000000000001403 89.0
HFD2_k127_4343837_5 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000001054 85.0
HFD2_k127_434612_0 ABC-type multidrug transport system ATPase and permease K06147 - - 1.487e-211 673.0
HFD2_k127_434612_1 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000001271 110.0
HFD2_k127_434612_2 Protease prsW family - - - 0.0000004272 63.0
HFD2_k127_434960_0 SMART PAS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000001233 240.0
HFD2_k127_434960_1 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000005619 168.0
HFD2_k127_4350135_0 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009461 419.0
HFD2_k127_4350135_1 Mo-molybdopterin cofactor metabolic process K03638 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000003568 229.0
HFD2_k127_4350135_2 PFAM lipopolysaccharide biosynthesis protein K08253 - 2.7.10.2 0.000000000000000000000000000000000000000000000000000000000000000006448 247.0
HFD2_k127_4350135_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000002019 140.0
HFD2_k127_4350135_4 PFAM Stage V sporulation protein S K06416 - - 0.000000000000000000000000001082 116.0
HFD2_k127_4350135_5 Lipopolysaccharide biosynthesis protein - - - 0.000000000000000000001188 105.0
HFD2_k127_4350135_6 AI-2E family transporter - - - 0.00000000000000000002356 98.0
HFD2_k127_4350135_7 TIGRFAM TIGR03032 family protein - - - 0.0002336 46.0
HFD2_k127_4355856_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 545.0
HFD2_k127_4355856_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 377.0
HFD2_k127_4355856_2 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000001579 255.0
HFD2_k127_4355856_3 Histidine kinase - - - 0.000000000000000000004703 98.0
HFD2_k127_4355856_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000311 78.0
HFD2_k127_4355856_5 CHASE - - - 0.000000000001958 72.0
HFD2_k127_4361667_0 Glycosyl hydrolases family 38 C-terminal domain K01191 - 3.2.1.24 0.0 1330.0
HFD2_k127_4361667_1 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000006462 199.0
HFD2_k127_4363486_0 2-hydroxy-3-oxopropionate reductase K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 322.0
HFD2_k127_4363486_1 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000004648 224.0
HFD2_k127_4363486_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000001029 180.0
HFD2_k127_4363486_3 YGGT family K02221 - - 0.0000000000000474 75.0
HFD2_k127_4363486_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000001373 74.0
HFD2_k127_4363486_5 Belongs to the UPF0235 family K09131 - - 0.0000000000004481 74.0
HFD2_k127_4363486_6 Forkhead associated domain - - - 0.000001061 61.0
HFD2_k127_4363540_0 import. Responsible for energy coupling to the transport system K10441 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034219,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 490.0
HFD2_k127_4363540_2 Belongs to the binding-protein-dependent transport system permease family K10440,K10538 - - 0.000000000000000000000000000000000000000000000000002847 203.0
HFD2_k127_4365845_0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 602.0
HFD2_k127_4365845_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 594.0
HFD2_k127_4365845_2 ABC transporter K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 504.0
HFD2_k127_4365845_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 400.0
HFD2_k127_4365845_4 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 332.0
HFD2_k127_4365845_5 Belongs to the binding-protein-dependent transport system permease family K02057,K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 329.0
HFD2_k127_4365845_6 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000002074 228.0
HFD2_k127_4365845_7 Glucose-6-phosphate dehydrogenase subunit - - - 0.00000000000000000000000000003795 134.0
HFD2_k127_4375274_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000000000000000000000000000000003379 177.0
HFD2_k127_4375274_1 denitrification pathway K15876 - - 0.000000000000000000000000000000000000000000000964 171.0
HFD2_k127_4375274_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000001417 130.0
HFD2_k127_437824_0 histidine kinase A domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000008695 236.0
HFD2_k127_437824_1 Putative heavy-metal chelation K09138 - - 0.000000000000000000000000000000000000000000000000000000000004468 216.0
HFD2_k127_437824_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000001463 159.0
HFD2_k127_437824_3 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000903 117.0
HFD2_k127_437824_4 - - - - 0.0000000000000000000004263 100.0
HFD2_k127_437824_5 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.000000005931 61.0
HFD2_k127_437824_7 acetyltransferase K17840 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008080,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016020,GO:0016137,GO:0016139,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017001,GO:0017144,GO:0030647,GO:0030649,GO:0034069,GO:0044237,GO:0044248,GO:0044464,GO:0047921,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901575,GO:1901657,GO:1901658 2.3.1.59 0.0001203 51.0
HFD2_k127_4383018_0 sequence-specific DNA binding - - - 0.00000000000000000000000000000000000009179 152.0
HFD2_k127_4383018_1 Bacterial transcriptional activator domain - - - 0.0000000007843 67.0
HFD2_k127_4383018_2 serine threonine protein kinase - - - 0.00038 53.0
HFD2_k127_4383055_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 562.0
HFD2_k127_4383055_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 514.0
HFD2_k127_4383055_10 Phospholipase/Carboxylesterase - - - 0.0000007289 60.0
HFD2_k127_4383055_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004727 251.0
HFD2_k127_4383055_3 cyclic nucleotide-binding K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000006872 243.0
HFD2_k127_4383055_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000197 218.0
HFD2_k127_4383055_5 Belongs to the citrate synthase family K01647,K15234 - 2.3.3.1,4.1.3.34 0.00000000000000000000000000000000000000000000001044 186.0
HFD2_k127_4383055_6 Virulence activator alpha C-term - - - 0.0000000000000000000000000000000000000000000001378 176.0
HFD2_k127_4383055_7 MacB-like periplasmic core domain K02004 - - 0.000000000000000001446 99.0
HFD2_k127_4383055_8 Esterase PHB depolymerase - - - 0.000000000000000805 80.0
HFD2_k127_4383055_9 FtsX-like permease family K02004 - - 0.0000000001034 74.0
HFD2_k127_4385898_0 ABC transporter, transmembrane region K06147 - - 5.862e-205 655.0
HFD2_k127_4385898_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 331.0
HFD2_k127_4385898_2 PFAM fumarate lyase K01679 - 4.2.1.2 0.000000000000000000000001606 104.0
HFD2_k127_4385898_3 Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000002142 63.0
HFD2_k127_4386406_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 404.0
HFD2_k127_4386406_1 carbohydrate transport K02027,K10117,K11751 - 3.1.3.5,3.6.1.45 0.000000000000000000000005069 117.0
HFD2_k127_4386860_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 409.0
HFD2_k127_4386860_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000007192 241.0
HFD2_k127_4386860_2 Peptidase family S41 - - - 0.000000000000000000000000000000000000000000000000000000000000000004598 240.0
HFD2_k127_4386860_3 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000001095 185.0
HFD2_k127_4390768_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 3.982e-223 706.0
HFD2_k127_4390768_1 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002426 289.0
HFD2_k127_4390768_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000003716 256.0
HFD2_k127_4390851_0 WD-40 repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 632.0
HFD2_k127_4390851_1 serine threonine protein kinase K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.0000000000000000000000000000000000000000000000000000006158 222.0
HFD2_k127_4390851_2 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.0000009142 56.0
HFD2_k127_4400247_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009765 349.0
HFD2_k127_4400247_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 297.0
HFD2_k127_4400247_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000002337 189.0
HFD2_k127_4400247_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000009035 165.0
HFD2_k127_4400247_4 tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000008738 146.0
HFD2_k127_4408871_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 486.0
HFD2_k127_4408871_1 COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family - - - 0.0000000000000000000000000000000000000000000000002024 183.0
HFD2_k127_441024_0 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 412.0
HFD2_k127_441024_1 Fumarylacetoacetate (FAA) hydrolase family K14259 - 4.2.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 355.0
HFD2_k127_441024_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000001743 98.0
HFD2_k127_4415598_0 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 381.0
HFD2_k127_4415598_1 PFAM AzlC family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 293.0
HFD2_k127_4415598_2 cell redox homeostasis K00322 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 291.0
HFD2_k127_4415598_3 Branched-chain amino acid transport protein (AzlD) - - - 0.000000000000000000000001388 107.0
HFD2_k127_4417464_0 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 317.0
HFD2_k127_4417464_1 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 327.0
HFD2_k127_4417464_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000001443 213.0
HFD2_k127_4417464_3 - - - - 0.0000000000000000000000000000000000000000000000000001003 211.0
HFD2_k127_4417464_5 Putative cyclase - - - 0.00000000000004479 74.0
HFD2_k127_442336_0 PFAM Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 340.0
HFD2_k127_442336_1 Radical_SAM C-terminal domain K07739 - 2.3.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005362 278.0
HFD2_k127_442336_2 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007024 251.0
HFD2_k127_442336_3 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000002743 226.0
HFD2_k127_442336_4 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798,K04076,K17681 - 3.4.21.53 0.00000000000000000000000000000000000002036 160.0
HFD2_k127_4433960_0 PFAM nickel-dependent hydrogenase, large subunit K00436,K14126 - 1.12.1.2,1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006146 433.0
HFD2_k127_4433960_1 PIN domain - - - 0.000000000000000000000000000007313 123.0
HFD2_k127_4433960_2 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000000000000005147 77.0
HFD2_k127_4433960_3 iron ion homeostasis - - - 0.000000001372 65.0
HFD2_k127_4435413_0 PFAM ABC transporter transmembrane region K06147,K18889 - - 0.00000000000000000000000000001912 129.0
HFD2_k127_4435413_1 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000911 120.0
HFD2_k127_4435413_2 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase - - - 0.00000000000000000000000000115 117.0
HFD2_k127_4435413_3 - - - - 0.00000000000000000000169 110.0
HFD2_k127_4435413_4 Thioredoxin - - - 0.000000000000148 79.0
HFD2_k127_4435413_5 Serine threonine protein kinase - - - 0.0000003934 57.0
HFD2_k127_4435413_6 PFAM ADP-ribosylation Crystallin J1 - - - 0.0000005363 57.0
HFD2_k127_4441434_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00520 - 1.16.1.1 1.76e-200 633.0
HFD2_k127_4441434_1 SIS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 412.0
HFD2_k127_4441434_2 ABC-type sugar transport system periplasmic component K02027,K05813 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 318.0
HFD2_k127_4441434_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 302.0
HFD2_k127_4441434_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004135 242.0
HFD2_k127_4441434_5 UTRA K03710 - - 0.000000000000000000000000000000000000006917 156.0
HFD2_k127_4441434_6 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000001643 130.0
HFD2_k127_4441434_7 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000001263 104.0
HFD2_k127_4441434_8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000001195 57.0
HFD2_k127_4450826_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006032 422.0
HFD2_k127_4450826_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 380.0
HFD2_k127_4450826_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 357.0
HFD2_k127_4450826_3 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 345.0
HFD2_k127_4450826_4 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009483 322.0
HFD2_k127_4450826_5 carboxylic acid catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000562 244.0
HFD2_k127_4450826_6 HD domain K07814 - - 0.00000000000000000000485 100.0
HFD2_k127_4450826_7 KaiC K08482 - - 0.00000000000000000002401 94.0
HFD2_k127_4454659_0 Sulfatase-modifying factor enzyme 1 K20333 - - 8.712e-245 792.0
HFD2_k127_4456041_0 PFAM ABC transporter related K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 297.0
HFD2_k127_4456041_1 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000003155 242.0
HFD2_k127_4459754_0 - K02450 - - 0.00000000000000000000000000000000000000000000000001403 190.0
HFD2_k127_4459754_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000001041 171.0
HFD2_k127_4459754_2 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000031 168.0
HFD2_k127_4459754_3 ABC transporter K06158 - - 0.0000000000000000000000000001203 118.0
HFD2_k127_4459754_4 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000004391 111.0
HFD2_k127_4459754_5 Ethyl tert-butyl ether degradation - - - 0.000000000000000000814 91.0
HFD2_k127_4466120_0 PFAM Glycosyl Hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 603.0
HFD2_k127_4466120_1 acetyltransferase K17840 - 2.3.1.59 0.0000000000000000000000000000000000008591 145.0
HFD2_k127_4466120_2 AraC-like ligand binding domain - - - 0.0000000000000000000000007214 108.0
HFD2_k127_4466120_3 Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 0.0000000008171 62.0
HFD2_k127_4483079_0 Cellobiose phosphorylase K00702,K13688,K18675 - 2.4.1.20,2.4.1.280 0.0 1300.0
HFD2_k127_4489158_0 Carbamoyltransferase C-terminus K00612 - - 3.461e-244 767.0
HFD2_k127_4489158_1 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 320.0
HFD2_k127_4489158_2 - - - - 0.000000002027 61.0
HFD2_k127_4489442_0 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000879 552.0
HFD2_k127_4489442_1 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 350.0
HFD2_k127_4489442_2 methyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000104 137.0
HFD2_k127_4502201_0 NHLM bacteriocin system ABC transporter, peptidase ATP-binding protein - - - 1.351e-295 923.0
HFD2_k127_4502201_1 NHLM bacteriocin system ABC transporter, ATP-binding protein K06148 - - 6.419e-243 783.0
HFD2_k127_4502201_2 Belongs to the DEAD box helicase family K05592 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003727,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010468,GO:0010501,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019439,GO:0022607,GO:0022613,GO:0022618,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0032268,GO:0032270,GO:0032574,GO:0032575,GO:0033554,GO:0033592,GO:0034057,GO:0034248,GO:0034250,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0034655,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043170,GO:0043487,GO:0043488,GO:0043489,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045934,GO:0046483,GO:0046700,GO:0048255,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070035,GO:0070417,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097617,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902369,GO:1902373,GO:1903311,GO:1903312,GO:2000112 3.6.4.13 1.923e-195 618.0
HFD2_k127_4502201_3 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000007075 156.0
HFD2_k127_450488_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 339.0
HFD2_k127_450488_1 PFAM SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002525 254.0
HFD2_k127_450488_2 Integrase catalytic - - - 0.0000000000000000116 84.0
HFD2_k127_4511222_0 PFAM Glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005666 248.0
HFD2_k127_4511222_1 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000001234 234.0
HFD2_k127_4511222_2 GTP binding - - - 0.0000000000000000000000000000000000000000001844 174.0
HFD2_k127_4511222_3 competence protein - - - 0.00000000000000000000000000000000000000001388 162.0
HFD2_k127_4511222_4 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000002417 159.0
HFD2_k127_4511222_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000009676 124.0
HFD2_k127_4511222_6 PFAM type II secretion system protein K12511 - - 0.00000000000000000000006548 99.0
HFD2_k127_4511293_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.075e-295 921.0
HFD2_k127_4511293_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003467 301.0
HFD2_k127_4511293_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000002242 221.0
HFD2_k127_4511293_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000001444 198.0
HFD2_k127_4511293_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000004504 125.0
HFD2_k127_4512901_0 Glycosyl hydrolase family 53 K01224 - 3.2.1.89 4.18e-224 710.0
HFD2_k127_4512901_10 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000492 202.0
HFD2_k127_4512901_11 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000004052 187.0
HFD2_k127_4512901_12 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000000000000000000000000297 163.0
HFD2_k127_4512901_13 Serine aminopeptidase, S33 - - - 0.0000000000000000000000002999 115.0
HFD2_k127_4512901_2 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 459.0
HFD2_k127_4512901_3 Peptidase dimerisation domain protein K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 380.0
HFD2_k127_4512901_4 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001057 302.0
HFD2_k127_4512901_5 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004234 288.0
HFD2_k127_4512901_6 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004784 296.0
HFD2_k127_4512901_7 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002721 278.0
HFD2_k127_4512901_8 PFAM Branched-chain amino acid transport system permease component K10440 - - 0.0000000000000000000000000000000000000000000000000000000007611 213.0
HFD2_k127_4512901_9 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000004298 212.0
HFD2_k127_4524333_0 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 1.259e-204 647.0
HFD2_k127_4524333_1 ABC transporter substrate-binding protein K02027,K05813 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 441.0
HFD2_k127_4524333_10 Transglycosylase SLT domain - - - 0.000000000000000000000000000000003302 140.0
HFD2_k127_4524333_11 Protein conserved in bacteria K03886 - - 0.00000000000000002936 91.0
HFD2_k127_4524333_12 - - - - 0.00000000000001168 78.0
HFD2_k127_4524333_13 glucose-6-phosphate isomerase K06859 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.3.1.9 0.000000000003485 72.0
HFD2_k127_4524333_14 Cytochrome c K08738 - - 0.0000000005677 65.0
HFD2_k127_4524333_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 370.0
HFD2_k127_4524333_3 Binding-protein-dependent transport system inner membrane component K02025,K15771 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 299.0
HFD2_k127_4524333_4 helix_turn _helix lactose operon repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002328 290.0
HFD2_k127_4524333_5 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002357 282.0
HFD2_k127_4524333_6 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000002874 240.0
HFD2_k127_4524333_7 glycerophosphodiester transmembrane transport K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000002203 231.0
HFD2_k127_4524333_8 transmembrane transport K02025,K05814,K10118,K10237,K15771,K17235,K17238,K17316 - - 0.0000000000000000000000000000000000000000000000000000000000000006843 231.0
HFD2_k127_4524333_9 glucose-6-phosphate isomerase K06859 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.3.1.9 0.000000000000000000000000000000002257 132.0
HFD2_k127_4528800_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000000003199 202.0
HFD2_k127_4528800_1 superoxide dismutase activity K02674,K04565 - 1.15.1.1 0.000000000000000000000000000000000001548 156.0
HFD2_k127_4528800_2 self proteolysis - - - 0.0000000000000000000000000001124 130.0
HFD2_k127_4528800_3 Dual specificity phosphatase, catalytic domain - - - 0.000000003915 64.0
HFD2_k127_4528800_4 SH3, type 3 domain protein K02415,K07448 - - 0.00009995 54.0
HFD2_k127_4529394_0 WD domain, G-beta repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000001344 260.0
HFD2_k127_4535009_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001952 298.0
HFD2_k127_4535824_0 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 349.0
HFD2_k127_4535824_1 FES K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000009229 159.0
HFD2_k127_4535824_2 PFAM LmbE family protein - - - 0.000000000000000000000000000000002429 136.0
HFD2_k127_4552367_0 Domain of unknown function K03737 - 1.2.7.1 0.0 1762.0
HFD2_k127_4552367_1 Belongs to the carbamoyltransferase HypF family K04656 - - 3.703e-303 950.0
HFD2_k127_4552367_10 Bacterial extracellular solute-binding protein K02027 - - 0.000002193 56.0
HFD2_k127_4552367_2 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 571.0
HFD2_k127_4552367_3 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 473.0
HFD2_k127_4552367_4 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 479.0
HFD2_k127_4552367_5 Transposase (IS116 IS110 IS902 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 423.0
HFD2_k127_4552367_6 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 352.0
HFD2_k127_4552367_7 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000004195 256.0
HFD2_k127_4552367_8 PFAM DegV family protein - - - 0.000000000000000000000000000000000000000000000000000000001655 210.0
HFD2_k127_4552367_9 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000000000000009597 111.0
HFD2_k127_4562062_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 299.0
HFD2_k127_4562062_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000001062 263.0
HFD2_k127_4562062_2 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000001216 165.0
HFD2_k127_4562062_3 dipeptide transport K02035 - - 0.00000000000000000000000000000000003245 143.0
HFD2_k127_4562062_4 Methyltransferase domain - - - 0.000000000000000000000000002994 119.0
HFD2_k127_4562062_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000002988 70.0
HFD2_k127_4565548_0 Ntpase (Nacht family) K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 361.0
HFD2_k127_4588516_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 4.331e-307 969.0
HFD2_k127_4588516_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000005868 182.0
HFD2_k127_4588516_2 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K02548,K03179,K17105 - 2.5.1.39,2.5.1.42,2.5.1.74 0.00000000000000000000007507 102.0
HFD2_k127_4589725_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 607.0
HFD2_k127_4589725_1 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 506.0
HFD2_k127_4589725_2 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 490.0
HFD2_k127_4589725_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 472.0
HFD2_k127_4589725_4 Purine catabolism regulatory protein-like family K09684 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002804 282.0
HFD2_k127_4589725_5 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002478 233.0
HFD2_k127_4589725_6 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000000000000000000000000000000000000008387 167.0
HFD2_k127_4589725_7 Protein of unknown function DUF58 - - - 0.000000000000000001491 86.0
HFD2_k127_4591672_0 PFAM glycosyl transferase family 3 K00756 - 2.4.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 507.0
HFD2_k127_4591672_1 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004368 258.0
HFD2_k127_4591672_2 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000001267 237.0
HFD2_k127_4591672_3 Sulfatase-modifying factor enzyme 1 K18912 - 1.14.99.50 0.0000000000000000000000000000000000001505 150.0
HFD2_k127_4591672_4 COG1651 Protein-disulfide isomerase - - - 0.00000000000000000001067 102.0
HFD2_k127_4591672_5 Glyoxalase-like domain - - - 0.000000000000000006816 88.0
HFD2_k127_4592476_0 PFAM 4Fe-4S K00184,K21308 - - 7.864e-241 767.0
HFD2_k127_4592476_1 Cytochrome c7 and related cytochrome c K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.000000000000000000000000000000000000000000000000000000000000000000006162 240.0
HFD2_k127_4592476_2 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000001352 207.0
HFD2_k127_4592476_3 family 4 K01222 - 3.2.1.86 0.00000000000000000000000000000000000000000003786 166.0
HFD2_k127_4598394_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 3.681e-294 911.0
HFD2_k127_4598394_1 carbohydrate kinase FGGY K00851 - 2.7.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 306.0
HFD2_k127_4598394_2 - - - - 0.000000000000000000000000000000001106 142.0
HFD2_k127_4608947_0 dipeptide transport K02035 - - 9.312e-283 883.0
HFD2_k127_4608947_1 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 3.386e-200 634.0
HFD2_k127_4608947_2 nitrogen compound transport K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 464.0
HFD2_k127_4608947_3 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 390.0
HFD2_k127_4608947_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 389.0
HFD2_k127_4608947_5 ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 302.0
HFD2_k127_4608947_6 ABC transporter permease K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006074 257.0
HFD2_k127_4608947_7 zinc-finger binding domain of transposase IS66 K07484 - - 0.00000000000000000000000000000000000000000000000000000001056 209.0
HFD2_k127_4608947_8 Transposase IS66 family K07484 - - 0.0000000000001701 75.0
HFD2_k127_4608947_9 transposase activity - - - 0.0000000004084 66.0
HFD2_k127_4609114_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01847,K01848 - 5.4.99.2 7.736e-246 770.0
HFD2_k127_4609114_1 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 5.808e-240 750.0
HFD2_k127_4609114_2 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 417.0
HFD2_k127_4609114_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000001339 92.0
HFD2_k127_4617055_0 Fibronectin type III-like domain K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 380.0
HFD2_k127_4620241_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 425.0
HFD2_k127_4620241_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 384.0
HFD2_k127_4620241_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000003535 261.0
HFD2_k127_4620241_3 Protein of unknown function (DUF559) - - - 0.0000000000000000000000007696 106.0
HFD2_k127_4635424_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1107.0
HFD2_k127_4635424_1 L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp K01876,K09759 - 6.1.1.12,6.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009175 432.0
HFD2_k127_4635424_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0000002152 61.0
HFD2_k127_4639449_0 Immune inhibitor A peptidase M6 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 321.0
HFD2_k127_4639449_1 PhoQ Sensor K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000005634 130.0
HFD2_k127_4640169_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000004535 258.0
HFD2_k127_4640169_1 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000003403 259.0
HFD2_k127_4640169_10 PFAM Forkhead-associated protein - - - 0.000000000000000000004677 99.0
HFD2_k127_4640169_11 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000001861 66.0
HFD2_k127_4640169_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000648 233.0
HFD2_k127_4640169_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000003614 220.0
HFD2_k127_4640169_4 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000001807 212.0
HFD2_k127_4640169_5 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - 0.000000000000000000000000000000000000000000000000009 184.0
HFD2_k127_4640169_6 Acyl-transferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000004292 168.0
HFD2_k127_4640169_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000004258 157.0
HFD2_k127_4640169_8 OsmC-like protein K06889,K07397 - - 0.000000000000000000000000000002172 127.0
HFD2_k127_4640169_9 Cytidine and deoxycytidylate deaminase zinc-binding region - - - 0.000000000000000000000000000006302 121.0
HFD2_k127_4648352_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000003392 255.0
HFD2_k127_4648352_1 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000001145 234.0
HFD2_k127_4648352_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000001176 233.0
HFD2_k127_4648352_3 PRC-barrel domain - - - 0.00000000000001796 81.0
HFD2_k127_4650251_0 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007724 531.0
HFD2_k127_4650251_1 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000462 257.0
HFD2_k127_4650251_2 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000002314 176.0
HFD2_k127_4650251_3 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000004301 167.0
HFD2_k127_4650251_4 F420H(2)-dependent quinone reductase - - - 0.000000000000000000003545 98.0
HFD2_k127_4650251_5 amine dehydrogenase activity - - - 0.00000000000000000004659 98.0
HFD2_k127_4650251_6 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03325,K03741 - 1.20.4.1 0.000000000003408 72.0
HFD2_k127_4650251_7 amine dehydrogenase activity - - - 0.0000002464 62.0
HFD2_k127_4652669_0 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 441.0
HFD2_k127_4652669_1 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 333.0
HFD2_k127_4652669_2 transcriptional - - - 0.0000000000000000000000000000003757 130.0
HFD2_k127_4652669_3 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000000005037 72.0
HFD2_k127_4682884_0 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000278 228.0
HFD2_k127_4682884_1 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000000008097 174.0
HFD2_k127_4682884_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000347 58.0
HFD2_k127_4692235_0 helix_turn_helix, Lux Regulon K03556 - - 7.591e-314 985.0
HFD2_k127_4692235_1 - - - - 0.0000000000000000000008498 99.0
HFD2_k127_4696108_0 Domain of unknown function (DUF3471) - - - 0.0000000000000000000000000000000000000000000000000000000000004743 229.0
HFD2_k127_4708649_0 Two component transcriptional regulator, winged helix family K07658 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003875 276.0
HFD2_k127_4708649_1 histidine kinase A domain protein K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001003 287.0
HFD2_k127_4708649_2 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000003523 207.0
HFD2_k127_4708649_3 domain, Protein - - - 0.000000000000000000000000000001029 138.0
HFD2_k127_4709805_0 ABC transporter transmembrane region K06147 - - 1.48e-209 667.0
HFD2_k127_4709805_1 ABC transporter transmembrane region K06147 - - 1.832e-200 641.0
HFD2_k127_4709805_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 555.0
HFD2_k127_4709805_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 410.0
HFD2_k127_4709805_4 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 363.0
HFD2_k127_4709805_5 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005867 312.0
HFD2_k127_4709805_6 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000002465 207.0
HFD2_k127_4709805_7 Iron-containing alcohol dehydrogenase K00001,K01714,K13954 - 1.1.1.1,4.3.3.7 0.00000000000000000000000000000000000000000000000000000005069 201.0
HFD2_k127_4709805_8 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000002688 195.0
HFD2_k127_4713487_0 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 480.0
HFD2_k127_4713487_1 COG3263 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005896 401.0
HFD2_k127_4713487_2 COG3263 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009073 273.0
HFD2_k127_4713487_3 Integrase - - - 0.00000000000000000000000000000000000000000005863 164.0
HFD2_k127_4713487_4 addiction module antidote protein K07746 GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0046983,GO:0051259,GO:0051262,GO:0051290,GO:0051291,GO:0065003,GO:0071840 - 0.00000000000000000000000002279 113.0
HFD2_k127_4713487_5 Transposase and inactivated derivatives IS30 family - - - 0.000000000000007257 78.0
HFD2_k127_47177_0 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 423.0
HFD2_k127_47177_1 Swim zinc finger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007962 425.0
HFD2_k127_47177_2 RNA polymerase II transcriptional preinitiation complex assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001636 294.0
HFD2_k127_47177_3 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000000000000000000006948 166.0
HFD2_k127_47177_4 PFAM ATPase associated with various cellular activities, AAA_5 - - - 0.0000000000000000000000000000000004558 132.0
HFD2_k127_47177_5 Phage shock protein A K03969 - - 0.0000000000000000000000000002662 123.0
HFD2_k127_4720370_0 Putative serine dehydratase domain K20757 - 4.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 403.0
HFD2_k127_4720370_1 PFAM von Willebrand factor type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 325.0
HFD2_k127_4720370_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000001413 91.0
HFD2_k127_4735290_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 392.0
HFD2_k127_4735290_1 PFAM regulatory protein, LysR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 298.0
HFD2_k127_4735290_2 trans-aconitate 2-methyltransferase activity K00598,K02169 - 2.1.1.144,2.1.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001118 276.0
HFD2_k127_4737838_0 PFAM sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 446.0
HFD2_k127_4737838_1 PHP domain protein K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 326.0
HFD2_k127_4737838_2 PFAM PSP1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001353 265.0
HFD2_k127_4737838_3 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006966 246.0
HFD2_k127_4737838_4 PFAM glycosyl transferase family 2 K07011 - - 0.00000000000000000000133 96.0
HFD2_k127_4737838_5 nuclear chromosome segregation - - - 0.00002192 55.0
HFD2_k127_4743175_0 Alanine-glyoxylate amino-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 344.0
HFD2_k127_4743175_1 Family of unknown function (DUF1028) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003751 282.0
HFD2_k127_4743175_2 Haloacid dehalogenase-like hydrolase K01101 - 3.1.3.41 0.000000000000000000000000000000000000000000000000000000000000002952 226.0
HFD2_k127_4743175_3 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000001181 136.0
HFD2_k127_4743175_4 Peptidase MA superfamily - - - 0.0001139 54.0
HFD2_k127_4743175_5 aminopeptidase N - - - 0.0004507 52.0
HFD2_k127_4751305_0 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 491.0
HFD2_k127_4751305_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008952 466.0
HFD2_k127_4751305_10 PFAM Stage V sporulation protein S K06416 - - 0.0000000000000000000000000003887 118.0
HFD2_k127_4751305_11 phosphorelay signal transduction system K02481,K07714 - - 0.000000000000000000000005041 111.0
HFD2_k127_4751305_12 Nucleoside H+ symporter K05820 - - 0.00000000000000000006812 103.0
HFD2_k127_4751305_2 PFAM basic membrane lipoprotein K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 346.0
HFD2_k127_4751305_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008002 313.0
HFD2_k127_4751305_4 Encoded by - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 305.0
HFD2_k127_4751305_5 Domain of unknown function (DUF4118) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 314.0
HFD2_k127_4751305_6 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000414 284.0
HFD2_k127_4751305_7 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000002534 218.0
HFD2_k127_4751305_8 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000003265 142.0
HFD2_k127_4751305_9 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000001493 117.0
HFD2_k127_475640_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 4.74e-293 911.0
HFD2_k127_475640_1 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007974 332.0
HFD2_k127_4765020_0 heavy metal translocating P-type ATPase K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005676 312.0
HFD2_k127_4765020_1 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.0000000000000000000000000000000000000001069 162.0
HFD2_k127_4766876_0 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002471 259.0
HFD2_k127_4766876_1 Glycosyl hydrolases family 39 - - - 0.00000000000000000000000000000000000000002796 169.0
HFD2_k127_4766876_2 PFAM Endonuclease Exonuclease phosphatase - - - 0.000000000000000000002899 102.0
HFD2_k127_4766876_3 oxidation-reduction process - - - 0.00000000000001856 73.0
HFD2_k127_4767625_0 Fibronectin type III-like domain K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 603.0
HFD2_k127_4767625_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 441.0
HFD2_k127_4767625_2 extracellular polysaccharide biosynthetic process K16554 - - 0.000000000000000001183 97.0
HFD2_k127_4767625_3 Glycosyl hydrolases family 25 - - - 0.0000008334 55.0
HFD2_k127_4774660_0 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 469.0
HFD2_k127_4774660_1 homoserine kinase K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000002636 239.0
HFD2_k127_4780356_0 MotA TolQ ExbB proton channel K03561,K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 390.0
HFD2_k127_4780356_1 TIGRFAM TonB K03832 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 338.0
HFD2_k127_4780356_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008294 333.0
HFD2_k127_4780356_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000003444 216.0
HFD2_k127_4780356_4 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000000000000000000000000000000000000000000001878 211.0
HFD2_k127_4780356_5 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000000000000000000000000000000000000000008774 198.0
HFD2_k127_4785685_0 Thiamine pyrophosphate enzyme, central domain K03336 - 3.7.1.22 4.546e-262 820.0
HFD2_k127_4785685_1 helix_turn_helix isocitrate lyase regulation K13641 - - 0.0000000000000000000000000000000000000000000000000006877 194.0
HFD2_k127_4785685_2 Oxidoreductase family, NAD-binding Rossmann fold K00010 - 1.1.1.18,1.1.1.369 0.000000000000000000000000000001275 125.0
HFD2_k127_479495_0 COGs COG3127 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000003426 226.0
HFD2_k127_479495_1 protein kinase activity - - - 0.0004646 47.0
HFD2_k127_4799651_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K14090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 595.0
HFD2_k127_4799651_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001389 291.0
HFD2_k127_4799651_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332,K13378 - 1.6.5.3 0.0000000000000000000000000000004257 127.0
HFD2_k127_4799651_4 quinone binding K00337 - 1.6.5.3 0.0000000000000002523 79.0
HFD2_k127_4804107_0 Glycosyl hydrolases family 2, TIM barrel domain K01190 - 3.2.1.23 4.375e-205 666.0
HFD2_k127_4804107_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009555 505.0
HFD2_k127_4804107_2 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 448.0
HFD2_k127_4804107_3 WD40 repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 472.0
HFD2_k127_4804107_4 Putative auto-transporter adhesin, head GIN domain - - - 0.000000000000000000000000000000000000000001977 163.0
HFD2_k127_4804107_5 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000000459 149.0
HFD2_k127_4804107_6 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000003801 139.0
HFD2_k127_4804107_7 energy transducer activity K03531,K03832 - - 0.000000000000000000000000000002726 135.0
HFD2_k127_4804107_8 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - 0.0000000000000000000000000009391 124.0
HFD2_k127_4804107_9 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000001785 97.0
HFD2_k127_4805334_0 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 318.0
HFD2_k127_4805334_1 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000768 51.0
HFD2_k127_4816162_0 PFAM type II secretion system protein E K02283 - - 4.548e-206 650.0
HFD2_k127_4816162_1 PFAM response regulator receiver K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009011 328.0
HFD2_k127_4816162_2 Flp pilus assembly protein CpaB K02279 - - 0.0000000000002398 76.0
HFD2_k127_482671_0 oxidoreductase activity K11089 - - 7.579e-198 631.0
HFD2_k127_4827980_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 323.0
HFD2_k127_4827980_1 lipoprotein transporter activity K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006588 282.0
HFD2_k127_4827980_2 Efflux ABC transporter permease protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001938 285.0
HFD2_k127_4827980_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000001667 90.0
HFD2_k127_4827980_4 HlyD family secretion protein K02005 - - 0.000000000008929 78.0
HFD2_k127_4853670_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002029 269.0
HFD2_k127_4853670_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009475 249.0
HFD2_k127_4853670_2 - - - - 0.0000000000000000000000025 105.0
HFD2_k127_4854640_0 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 321.0
HFD2_k127_4854640_1 binding-protein-dependent transport systems inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009014 263.0
HFD2_k127_4854640_2 PFAM binding-protein-dependent transport systems inner membrane component K02025,K05814,K10118 - - 0.0000000000000000000000000000000000000000000000000000000006742 208.0
HFD2_k127_4861478_0 Belongs to the acetylglutamate kinase family. LysZ subfamily K05828 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 297.0
HFD2_k127_4861478_1 4Fe-4S binding domain K00184 - - 0.000000000000000000000000000000000000000000000000000004742 199.0
HFD2_k127_4861478_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000001499 205.0
HFD2_k127_4861478_3 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000002033 127.0
HFD2_k127_4861478_4 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000001299 68.0
HFD2_k127_4868072_0 PFAM peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000191 259.0
HFD2_k127_4868072_1 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001262 236.0
HFD2_k127_4868072_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000002628 237.0
HFD2_k127_4868072_3 type I restriction modification DNA specificity domain - - - 0.000000000000000000000000002855 124.0
HFD2_k127_4868072_4 Belongs to the peptidase S8 family - - - 0.000000000000000000009366 104.0
HFD2_k127_4868072_5 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.0000000000000008445 79.0
HFD2_k127_4868072_6 PFAM Transglycosylase SLT domain - - - 0.00000000000005584 83.0
HFD2_k127_4876284_0 Belongs to the glycosyl hydrolase 2 family K01195 GO:0003674,GO:0003824,GO:0004553,GO:0004566,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016043,GO:0016052,GO:0016054,GO:0016137,GO:0016139,GO:0016787,GO:0016798,GO:0019389,GO:0019391,GO:0019752,GO:0022607,GO:0042802,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901136,GO:1901575,GO:1901657,GO:1901658 3.2.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008548 551.0
HFD2_k127_4876284_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 412.0
HFD2_k127_4876284_2 Glycosyl Hydrolase Family 88 K18581 - 3.2.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 320.0
HFD2_k127_4883329_0 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 313.0
HFD2_k127_4888213_0 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 394.0
HFD2_k127_4891019_0 ABC transporter (Permease) K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 375.0
HFD2_k127_4891019_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 341.0
HFD2_k127_4891019_2 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000003277 139.0
HFD2_k127_4891019_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000002811 130.0
HFD2_k127_4891019_4 SnoaL-like polyketide cyclase - - - 0.000000000000000000000007733 106.0
HFD2_k127_4891019_5 COG2909 ATP-dependent transcriptional regulator K03556 - - 0.00000000000000000001033 105.0
HFD2_k127_489703_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 1.225e-317 999.0
HFD2_k127_489703_1 Domain of unknown function (DUF3524) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 388.0
HFD2_k127_489703_2 PFAM PfkB domain protein K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 355.0
HFD2_k127_489703_3 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 296.0
HFD2_k127_489703_4 Glycosyltransferase 28 domain K03715 - 2.4.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000002894 272.0
HFD2_k127_489703_5 CO dehydrogenase flavoprotein C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001623 268.0
HFD2_k127_489703_6 PFAM Formylglycine-generating sulfatase enzyme K20333 - - 0.000000000000000000000000000000000000000000000000000000000000000001683 246.0
HFD2_k127_489703_7 PFAM conserved K07027 - - 0.00000000000000002655 93.0
HFD2_k127_489703_8 Wd40 repeat-containing protein - - - 0.000000000004206 79.0
HFD2_k127_489703_9 Bacterial transcriptional activator domain - - - 0.000000157 63.0
HFD2_k127_4902360_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000001396 159.0
HFD2_k127_4902360_1 Histidine kinase - - - 0.00000000000000000000000000000000000000009675 174.0
HFD2_k127_4905837_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700,K01236 - 2.4.1.18,3.2.1.141 1.046e-230 732.0
HFD2_k127_4905837_1 synthase K00705,K06044 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576 2.4.1.25,5.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 565.0
HFD2_k127_4905837_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 319.0
HFD2_k127_491076_0 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 438.0
HFD2_k127_491076_1 Involved in the tonB-independent uptake of proteins - - - 0.000000001352 70.0
HFD2_k127_491076_2 involved in the tonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701 - 0.000005961 59.0
HFD2_k127_4915475_0 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000372 298.0
HFD2_k127_4918509_0 Belongs to the glycosyl hydrolase 31 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 446.0
HFD2_k127_4918509_1 Glycosyl hydrolases family 15 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 338.0
HFD2_k127_4918509_2 Sugar ABC transporter substrate-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002084 258.0
HFD2_k127_4923188_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 1.876e-255 816.0
HFD2_k127_4923188_1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001185 254.0
HFD2_k127_4923188_2 histidine kinase A domain protein K07646 - 2.7.13.3 0.00000000000000000000000000002817 120.0
HFD2_k127_4923188_3 amino acid - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.00000000000004235 86.0
HFD2_k127_4930110_0 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 331.0
HFD2_k127_4930110_1 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 309.0
HFD2_k127_4930110_2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K03825 GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 - 0.00000000000000000000000000000000000000000000000004152 184.0
HFD2_k127_4930110_3 Tetracyclin repressor, C-terminal all-alpha domain K18476 - - 0.0000000000000000000000000000001813 130.0
HFD2_k127_4930110_4 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00001274 51.0
HFD2_k127_4930110_5 Periplasmic component of the Tol biopolymer transport system - - - 0.00006153 53.0
HFD2_k127_493035_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 373.0
HFD2_k127_493035_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001501 256.0
HFD2_k127_493035_2 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000003414 183.0
HFD2_k127_493035_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000001884 132.0
HFD2_k127_493035_4 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000001144 102.0
HFD2_k127_493035_5 BFD domain protein 2Fe-2S -binding domain protein K00372 - - 0.0000117 50.0
HFD2_k127_4933450_0 COGs COG1132 ABC-type multidrug transport system ATPase and permease components K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003062 267.0
HFD2_k127_4933450_1 (ABC) transporter K06147,K06148 - - 0.00000000000000000000000000000000000000000000000000002234 190.0
HFD2_k127_4933761_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 618.0
HFD2_k127_4940512_0 glycoside hydrolase family 2 sugar binding K01192 - 3.2.1.25 5e-324 1010.0
HFD2_k127_4940512_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 1.829e-209 674.0
HFD2_k127_4940512_2 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 336.0
HFD2_k127_4940512_3 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004027 292.0
HFD2_k127_4940512_4 Histidine ammonia-lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000001799 220.0
HFD2_k127_4940512_5 PFAM YhhN family protein - - - 0.00000000000000000000000000000000000000000000000000000000001101 214.0
HFD2_k127_4941496_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008499 437.0
HFD2_k127_4941496_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02484,K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000003746 244.0
HFD2_k127_4941496_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000003209 230.0
HFD2_k127_4941496_3 pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000004089 80.0
HFD2_k127_4941496_4 ABC transporter - - - 0.000000000000006196 76.0
HFD2_k127_4941496_5 DNA-templated transcription, initiation K03088,K11333 - 1.3.7.14,1.3.7.15 0.000000000005747 72.0
HFD2_k127_4941496_6 - - - - 0.00003115 55.0
HFD2_k127_4954780_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000007735 269.0
HFD2_k127_4954780_1 PFAM Endonuclease Exonuclease phosphatase - - - 0.0000000000000000000000000000000000000002018 165.0
HFD2_k127_4954780_2 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.00000000000000000000000000000004396 136.0
HFD2_k127_4954780_3 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749 - - 0.000000000000000000000003706 105.0
HFD2_k127_4954780_4 Prolyl oligopeptidase family - - - 0.000000000000000324 92.0
HFD2_k127_4958560_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 444.0
HFD2_k127_4958560_1 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 330.0
HFD2_k127_4958560_2 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000002946 160.0
HFD2_k127_4958560_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000493 129.0
HFD2_k127_4961949_0 protein histidine kinase activity - - - 0.0000000000000000000000000000000003291 152.0
HFD2_k127_4961949_1 Response regulator receiver domain - - - 0.0000000000000000000000000000000005634 141.0
HFD2_k127_4961949_2 phosphorelay sensor kinase activity K13924 - 2.1.1.80,3.1.1.61 0.000000000000000591 93.0
HFD2_k127_4973135_0 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 523.0
HFD2_k127_4973135_1 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 413.0
HFD2_k127_4973135_2 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 381.0
HFD2_k127_4973135_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000002128 131.0
HFD2_k127_4973135_4 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000000000000000000000000006561 117.0
HFD2_k127_4973135_5 Glycosyltransferase family 36 - - - 0.00000000000000000002585 92.0
HFD2_k127_4973135_6 inositol 2-dehydrogenase activity - - - 0.00001362 51.0
HFD2_k127_497659_0 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 323.0
HFD2_k127_497659_1 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000001561 218.0
HFD2_k127_497659_2 PFAM ABC-2 type transporter K01992 - - 0.00000000000009882 83.0
HFD2_k127_497659_3 TIR domain - - - 0.0000000002544 73.0
HFD2_k127_4979000_0 MacB-like periplasmic core domain K02004 - - 2.676e-208 675.0
HFD2_k127_4979000_1 ABC transporter K02003 - - 0.00000000000000305 77.0
HFD2_k127_4988676_0 NHLM bacteriocin system ABC transporter, peptidase ATP-binding protein - - - 7.716e-287 901.0
HFD2_k127_4988676_1 protein secretion by the type I secretion system K06147 - - 0.0000000000000000000003146 108.0
HFD2_k127_499108_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000009678 130.0
HFD2_k127_499108_1 Lactonase, 7-bladed beta-propeller - - - 0.0000000000001325 85.0
HFD2_k127_499108_2 domain, Protein - - - 0.00000003887 65.0
HFD2_k127_499108_3 TadE-like protein - - - 0.000001249 62.0
HFD2_k127_499108_4 TadE-like protein - - - 0.000005109 55.0
HFD2_k127_4991499_0 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003849 276.0
HFD2_k127_4991499_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006072 259.0
HFD2_k127_4991499_2 Molybdenum cofactor sulfurase - - - 0.000000000007869 71.0
HFD2_k127_4991499_3 ADP binding - - - 0.000001383 59.0
HFD2_k127_499314_0 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 312.0
HFD2_k127_499314_1 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 308.0
HFD2_k127_499314_2 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 296.0
HFD2_k127_499314_3 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005703 245.0
HFD2_k127_499314_4 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000172 202.0
HFD2_k127_499314_5 Mandelate racemase muconate lactonizing enzyme K01706 - 4.2.1.40 0.000000000000000000000000000000000000000000000000002548 183.0
HFD2_k127_4993349_0 Peptidase family S41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001287 298.0
HFD2_k127_4993349_1 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000004736 103.0
HFD2_k127_4993349_2 Suppressor of fused protein (SUFU) - - - 0.0000000000000003768 87.0
HFD2_k127_4993349_3 PFAM Forkhead-associated protein - - - 0.0000000000203 72.0
HFD2_k127_4996675_0 U4 snRNA binding K11127 - - 0.000000000000000000000000000000000000000000008759 177.0
HFD2_k127_4996675_1 response regulator K07669 - - 0.00000000000000000000000004065 120.0
HFD2_k127_4996675_2 EamA-like transporter family - - - 0.0000000000000001142 83.0
HFD2_k127_4996675_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000086 61.0
HFD2_k127_4996907_0 MOSC domain - - - 0.00000000000000000000000000000000000000000000004299 173.0
HFD2_k127_4996907_1 subunit (C K02119 - - 0.0000000000000000000000000000000000000000000000483 184.0
HFD2_k127_5006019_0 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000003054 154.0
HFD2_k127_5008981_0 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 413.0
HFD2_k127_5008981_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005522 271.0
HFD2_k127_5008981_2 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006771 262.0
HFD2_k127_5008981_3 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000003884 248.0
HFD2_k127_5008981_4 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.00000000000000000000000000000000000000000000000000000000000003306 244.0
HFD2_k127_5008981_5 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000000073 109.0
HFD2_k127_5008981_6 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000008303 83.0
HFD2_k127_5008981_7 domain, Protein - - - 0.000000841 61.0
HFD2_k127_5009722_0 ABC transporter K10441,K10562 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 439.0
HFD2_k127_5009722_1 Branched-chain amino acid transport system / permease component K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 317.0
HFD2_k127_5009722_2 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 316.0
HFD2_k127_5028920_0 Calx-beta domain - - - 0.00000000000000005561 97.0
HFD2_k127_5028920_1 amine dehydrogenase activity K14647,K21449 - - 0.0002504 55.0
HFD2_k127_5036130_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 1.593e-267 850.0
HFD2_k127_5036130_1 PFAM heat shock protein DnaJ domain protein K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 312.0
HFD2_k127_5036130_2 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K08070 - 1.3.1.74,3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 300.0
HFD2_k127_5036130_3 protein histidine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000008699 254.0
HFD2_k127_5036130_4 CHASE - - - 0.00000000000000000000003132 107.0
HFD2_k127_5036130_5 Response regulator, receiver - - - 0.00000000000000009939 84.0
HFD2_k127_5043240_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009672 303.0
HFD2_k127_5043240_1 - - - - 0.0000000000000000000000000000000000000004969 162.0
HFD2_k127_5043240_2 MutL protein K00854 - 2.7.1.17 0.000000000000000000000000000002352 129.0
HFD2_k127_5046938_0 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 6.133e-292 905.0
HFD2_k127_5046938_1 Concanavalin A-like lectin/glucanases superfamily - - - 0.00000000000000000000000009614 109.0
HFD2_k127_5046938_2 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.00000000000000000000021 99.0
HFD2_k127_505736_0 Glucuronate isomerase K01812 - 5.3.1.12 4.7e-219 689.0
HFD2_k127_505736_1 tagaturonate epimerase K21619 - 5.1.2.7 4.495e-199 632.0
HFD2_k127_505736_10 - - - - 0.0000000002486 71.0
HFD2_k127_505736_2 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 486.0
HFD2_k127_505736_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 341.0
HFD2_k127_505736_4 putrescine transport K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 293.0
HFD2_k127_505736_5 DNA import into cell involved in transformation K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 288.0
HFD2_k127_505736_6 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007088 286.0
HFD2_k127_505736_7 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000005215 257.0
HFD2_k127_505736_8 purine nucleotide biosynthetic process K02529 - - 0.000000000000000000000000000000000000000000001749 171.0
HFD2_k127_505736_9 - - - - 0.0000000000000006455 87.0
HFD2_k127_507650_0 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 325.0
HFD2_k127_5080443_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000002165 214.0
HFD2_k127_5087151_0 PFAM Mo-co oxidoreductase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 430.0
HFD2_k127_5087151_1 cellulose binding - - - 0.000000000000000000000000000000000000000000007496 172.0
HFD2_k127_5087151_2 Histidine kinase - - - 0.00000000000008541 77.0
HFD2_k127_5087151_3 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000003965 72.0
HFD2_k127_5087151_4 PFAM TrkA-N domain K03499 - - 0.000000008059 60.0
HFD2_k127_5088559_0 DoxX K16937 - 1.8.5.2 0.0000000000000000000000000000000000000000000000000000000000001736 219.0
HFD2_k127_5088559_1 PFAM response regulator receiver - - - 0.00000000000000000004592 94.0
HFD2_k127_5088559_2 Alternative locus ID - - - 0.00000001689 67.0
HFD2_k127_5099069_0 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 434.0
HFD2_k127_5099069_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 395.0
HFD2_k127_5099069_2 Pfam Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 352.0
HFD2_k127_5099069_3 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 340.0
HFD2_k127_5107626_0 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00819,K00821 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.11,2.6.1.13,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008053 587.0
HFD2_k127_5107626_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000002814 252.0
HFD2_k127_5107626_2 hopanoid biosynthesis associated protein HpnK - - - 0.00000000000000000000000000000000000001072 156.0
HFD2_k127_5107626_3 Mannosyltransferase (PIG-V) - - - 0.000000000000000000000000008291 124.0
HFD2_k127_5113651_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 306.0
HFD2_k127_5113651_1 SPTR NmrA family protein - - - 0.00000000000000000000000000000000000000000000000001699 190.0
HFD2_k127_5113651_2 Virulence activator alpha C-term - - - 0.00000000000000000001114 98.0
HFD2_k127_5121333_0 WYL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 364.0
HFD2_k127_5121333_1 - - - - 0.000000000000000000000000000000000000000000000000006523 185.0
HFD2_k127_5121333_2 NIPSNAP - - - 0.000000000000000000000000000000000002862 146.0
HFD2_k127_5122251_0 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 640.0
HFD2_k127_5122251_1 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 424.0
HFD2_k127_5122251_11 - - - - 0.0000000000000001852 86.0
HFD2_k127_5122251_12 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000002604 71.0
HFD2_k127_5122251_13 transposition, DNA-mediated K02529,K20971 - - 0.0000004239 63.0
HFD2_k127_5122251_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 332.0
HFD2_k127_5122251_3 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000824 299.0
HFD2_k127_5122251_4 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000627 228.0
HFD2_k127_5122251_5 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000001825 231.0
HFD2_k127_5122251_6 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000009546 211.0
HFD2_k127_5122251_7 formate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000001132 209.0
HFD2_k127_5122251_8 Histidine kinase - - - 0.0000000000000000000000000000000000000000003755 171.0
HFD2_k127_5122251_9 SCP-2 sterol transfer family - - - 0.00000000000000000000000000000284 132.0
HFD2_k127_5122467_0 cobalamin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 368.0
HFD2_k127_5122467_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02484,K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 372.0
HFD2_k127_5122467_2 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000000000000000000000000000000000000008691 189.0
HFD2_k127_5126875_0 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 366.0
HFD2_k127_5126875_1 TIGRFAM phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 353.0
HFD2_k127_5126875_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 337.0
HFD2_k127_5126875_3 CHAT domain - - - 0.00000000000000000000000000000000005183 149.0
HFD2_k127_5126875_4 - - - - 0.000000000000000000000008698 107.0
HFD2_k127_5126875_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000003091 73.0
HFD2_k127_5126875_6 abc transporter, ATP-binding protein K01990 - - 0.0000002148 59.0
HFD2_k127_5130860_0 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 365.0
HFD2_k127_5130860_1 Anaphase-promoting complex subunit 4 WD40 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 302.0
HFD2_k127_5130860_2 Histidine kinase - - - 0.0000000000000000000001072 108.0
HFD2_k127_5130860_3 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.00000000000000002775 88.0
HFD2_k127_5130860_4 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000287 78.0
HFD2_k127_5131755_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 402.0
HFD2_k127_5131755_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 382.0
HFD2_k127_5131755_2 - - - - 0.00000000000000000000000000004841 118.0
HFD2_k127_5131755_3 amine dehydrogenase activity K01751,K01754 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008838,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575 4.3.1.15,4.3.1.19 0.0002456 48.0
HFD2_k127_5132616_0 proline dipeptidase activity - - - 9.469e-233 726.0
HFD2_k127_5132616_1 Predicted Zn-dependent protease (DUF2268) - - - 0.0000000000000000000000000000000000000000000000006801 187.0
HFD2_k127_5132616_2 Cupin domain - - - 0.0000000000000000000000000000000008928 141.0
HFD2_k127_5132616_3 Cupin domain - - - 0.0000000000000000000000000002927 120.0
HFD2_k127_5141585_0 elongation factor Tu domain 2 protein K02355 - - 5.876e-214 685.0
HFD2_k127_5141585_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000008697 251.0
HFD2_k127_5141970_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 1.938e-274 851.0
HFD2_k127_5141970_1 Putative carbohydrate binding domain K18675 - 2.4.1.280 4.888e-258 802.0
HFD2_k127_5141970_2 Metallo-beta-lactamase superfamily - - - 1.675e-202 648.0
HFD2_k127_5141970_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 333.0
HFD2_k127_5141970_4 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000001073 135.0
HFD2_k127_5148653_0 mannonate dehydratase activity K01686 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 347.0
HFD2_k127_5148653_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000001734 238.0
HFD2_k127_5148653_2 - - - - 0.000000000000000000000000000000000000000000000004175 199.0
HFD2_k127_5148653_3 Histidine kinase - - - 0.0000000000000000000000000000000000004562 163.0
HFD2_k127_5148653_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000001789 70.0
HFD2_k127_5156138_0 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 304.0
HFD2_k127_5156138_1 PFAM ABC transporter related K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000004195 168.0
HFD2_k127_5156138_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000001164 57.0
HFD2_k127_5161976_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000003392 213.0
HFD2_k127_5161976_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000001531 180.0
HFD2_k127_5161976_2 Histidine kinase K07777 - 2.7.13.3 0.000000000000000000000000000000000000000005584 174.0
HFD2_k127_5161976_3 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000001128 101.0
HFD2_k127_5164298_0 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000004978 268.0
HFD2_k127_5164298_1 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000363 247.0
HFD2_k127_5164298_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000006374 240.0
HFD2_k127_5164298_3 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000001583 59.0
HFD2_k127_5164298_4 virion core protein, lumpy skin disease virus - - - 0.00002984 52.0
HFD2_k127_5176063_0 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 2.59e-229 716.0
HFD2_k127_5176063_1 PFAM Bacterial regulatory proteins, lacI family K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000164 280.0
HFD2_k127_5176063_2 beta-1,4-mannooligosaccharide phosphorylase K20885 - 2.4.1.339,2.4.1.340 0.00000000000000000000005397 101.0
HFD2_k127_5176063_3 Glycosyl transferase K00728 - 2.4.1.109 0.0000000000000000000001929 112.0
HFD2_k127_5176063_4 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000005957 71.0
HFD2_k127_5181442_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 464.0
HFD2_k127_5181442_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 381.0
HFD2_k127_5181442_2 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001092 253.0
HFD2_k127_5181442_3 Protein involved in cellulose biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000009226 218.0
HFD2_k127_5181442_4 Bacterial sugar transferase K16566 - - 0.000000000000000000000000000000000000000000000000000000000531 217.0
HFD2_k127_5181442_5 PFAM lipopolysaccharide biosynthesis protein K08253 - 2.7.10.2 0.000000000000000000000000000000000000000000000000005729 199.0
HFD2_k127_5181442_6 - - - - 0.00000000000000000000000000000000000001588 153.0
HFD2_k127_5192657_0 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 355.0
HFD2_k127_5192657_1 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 323.0
HFD2_k127_5192657_2 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820,K15916 - 2.6.1.16,5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004267 280.0
HFD2_k127_5214159_0 Alcohol dehydrogenase zinc-binding domain protein K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 433.0
HFD2_k127_5214159_1 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 402.0
HFD2_k127_5214159_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 327.0
HFD2_k127_5214159_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 329.0
HFD2_k127_5214159_4 Short-chain dehydrogenase reductase SDR K22185,K22215 - 1.1.1.120,1.1.1.175,1.1.1.48 0.0000000000000000000000000000000000000003685 161.0
HFD2_k127_5214159_5 Belongs to the IlvD Edd family K22186 - 4.2.1.82 0.0000002775 53.0
HFD2_k127_5214159_6 Mandelate racemase muconate lactonizing enzyme K01684 - 4.2.1.6 0.000005543 51.0
HFD2_k127_5214928_0 Nitrite/Sulfite reductase ferredoxin-like half domain K00381,K00392 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006790,GO:0008150,GO:0008152,GO:0009337,GO:0009987,GO:0016002,GO:0016491,GO:0016667,GO:0016673,GO:0019419,GO:0032991,GO:0044237,GO:0044424,GO:0044464,GO:0050311,GO:0055114 1.8.1.2,1.8.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 549.0
HFD2_k127_5214928_1 sirohydrochlorin cobaltochelatase activity K03795 - 4.99.1.3 0.0000000000000000000000000000000000000000000000000001072 196.0
HFD2_k127_5217847_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.255e-276 879.0
HFD2_k127_5217847_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000602 351.0
HFD2_k127_5217847_2 Belongs to the SEDS family K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006273 271.0
HFD2_k127_5217847_3 Protein of unknown function (DUF1385) K09153 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006651 268.0
HFD2_k127_5217847_4 PFAM Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000004683 204.0
HFD2_k127_5217847_5 4-vinyl reductase, 4VR - - - 0.0000000000000000000000000000000000000000001884 166.0
HFD2_k127_5217847_6 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000008313 160.0
HFD2_k127_5217847_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000003197 72.0
HFD2_k127_5217847_8 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.0000002405 54.0
HFD2_k127_521880_0 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 357.0
HFD2_k127_521880_1 Haloacid dehalogenase domain protein hydrolase - - - 0.0000000000000000000000000000000000000000000000000000162 193.0
HFD2_k127_521880_2 Domain of unknown function (DUF389) - - - 0.00000000000000000000000000000000000000000003279 177.0
HFD2_k127_521880_3 Phosphoglucomutase/phosphomannomutase, C-terminal domain - - - 0.00000000000000000000007051 99.0
HFD2_k127_5221947_0 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 476.0
HFD2_k127_5228151_0 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000000000009391 168.0
HFD2_k127_5228151_1 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000007261 165.0
HFD2_k127_5228151_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000004613 135.0
HFD2_k127_5228151_3 Protein of unknown function (DUF2089) - - - 0.0000000000000000000000000000008044 126.0
HFD2_k127_5228151_4 - - - - 0.00000000000000000000000001012 113.0
HFD2_k127_5228151_5 PFAM DinB family protein - - - 0.0000000000000000000000475 105.0
HFD2_k127_5228151_6 - - - - 0.0000000000000001335 92.0
HFD2_k127_5228151_7 - - - - 0.000000002129 64.0
HFD2_k127_5228151_8 Beta-lactamase K01286 - 3.4.16.4 0.00000004154 61.0
HFD2_k127_5238064_0 glycerophosphodiester transmembrane transport K02026,K05815 - - 0.000000000000000000000000000000000000000000000000000000000000006355 240.0
HFD2_k127_5238064_1 PFAM binding-protein-dependent transport systems inner membrane component K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17316 - - 0.000000000000000000000000000000000001255 141.0
HFD2_k127_5238793_0 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 484.0
HFD2_k127_5238793_1 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006149 418.0
HFD2_k127_5238793_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000007462 252.0
HFD2_k127_5238793_3 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0002847 51.0
HFD2_k127_5242173_0 Permease K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 293.0
HFD2_k127_5242173_1 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001191 282.0
HFD2_k127_5242173_2 family 5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002066 253.0
HFD2_k127_5242173_3 -acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000001345 216.0
HFD2_k127_5252463_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 379.0
HFD2_k127_5252463_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 308.0
HFD2_k127_5252463_2 Putative restriction endonuclease - - - 0.0000000000000000000000000000000729 131.0
HFD2_k127_5252463_3 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000006028 114.0
HFD2_k127_5254666_0 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000004312 121.0
HFD2_k127_5254666_1 EamA-like transporter family - - - 0.000000000000000005925 94.0
HFD2_k127_5254666_2 PFAM ABC transporter related K01996 - - 0.000000000000000008685 85.0
HFD2_k127_5259761_0 Rhodanese Homology Domain K01011 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001256 277.0
HFD2_k127_5259761_1 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000006266 181.0
HFD2_k127_5259761_2 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000001104 114.0
HFD2_k127_5259761_3 intracellular signal transduction - - - 0.0000000000000001097 85.0
HFD2_k127_526673_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299,K03281 - 3.4.17.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 583.0
HFD2_k127_526673_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005814 507.0
HFD2_k127_526673_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 GO:0000049,GO:0000166,GO:0000287,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016020,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046983,GO:0070905,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 467.0
HFD2_k127_526673_3 carbohydrate transport K02027,K10117 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 331.0
HFD2_k127_526673_4 purine nucleotide biosynthetic process K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000003346 241.0
HFD2_k127_526673_5 NUDIX domain - - - 0.0000000000000000000000000000000000000000006872 164.0
HFD2_k127_526673_6 PFAM binding-protein-dependent transport systems inner membrane component K02025,K05814 - - 0.0000000000000000000000000000000004295 137.0
HFD2_k127_526673_7 PFAM MgtC K07507 - - 0.00000000000000000000000000002192 123.0
HFD2_k127_526673_8 - - - - 0.000000000000000000000002627 108.0
HFD2_k127_526673_9 - - - - 0.00003434 55.0
HFD2_k127_5267845_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain - - - 9.853e-239 747.0
HFD2_k127_5267845_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 295.0
HFD2_k127_5267845_2 Carbohydrate kinase - - - 0.00000000000000000000000000000000001009 141.0
HFD2_k127_5267845_3 Domain of unknown function (DUF389) - - - 0.00000000000000000000000000000000001915 151.0
HFD2_k127_5274440_0 transferase activity, transferring acyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 336.0
HFD2_k127_5274440_1 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000006356 204.0
HFD2_k127_5277285_0 Spermine/spermidine synthase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004024 273.0
HFD2_k127_5279574_0 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 442.0
HFD2_k127_5279574_1 UTRA K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 290.0
HFD2_k127_5282963_0 Non-specific serine threonine protein kinase K08282 - 2.7.11.1 2.366e-206 673.0
HFD2_k127_5282963_1 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000000000000005495 108.0
HFD2_k127_5287534_0 Binding-protein-dependent transport system inner membrane component K10118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 308.0
HFD2_k127_5287534_1 Bacterial extracellular solute-binding protein K02027,K10117 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003253 258.0
HFD2_k127_5287534_2 Binding-protein-dependent transport system inner membrane component K10119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008549 259.0
HFD2_k127_5287534_3 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000001334 219.0
HFD2_k127_5287534_4 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.00000000000000000000000000000000000000000000133 174.0
HFD2_k127_5287534_5 Protein conserved in bacteria - - - 0.0000000000000000000000000000000001959 136.0
HFD2_k127_5287534_6 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.0000000000000000008304 92.0
HFD2_k127_5291929_0 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 316.0
HFD2_k127_5298788_0 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.000000000000000000000000000000000000000000000000000000000000000004153 237.0
HFD2_k127_5298788_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000001453 114.0
HFD2_k127_5298788_2 integral membrane protein - - - 0.000000001987 64.0
HFD2_k127_5303254_0 ABC-type sugar transport system periplasmic component K17315 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006477 245.0
HFD2_k127_5303254_1 protein histidine kinase activity K03407,K07678 - 2.7.13.3 0.000000000000000000000000000000000000000004688 169.0
HFD2_k127_5303254_2 PhoQ Sensor K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000001524 162.0
HFD2_k127_5304421_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 564.0
HFD2_k127_5304421_1 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002549 247.0
HFD2_k127_5304421_2 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000002727 224.0
HFD2_k127_5304421_3 Von Willebrand factor - - - 0.0000000000000000000000000000000000000000000000000000001243 202.0
HFD2_k127_5304421_4 Stage V sporulation protein S (SpoVS) K06416 - - 0.000000000000000000000000000005042 121.0
HFD2_k127_5304421_5 Protein phosphatase 2C - - - 0.0000000000000308 85.0
HFD2_k127_5304421_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000001319 64.0
HFD2_k127_5304585_0 Resistance to Hg(2 ) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0) K00520 - 1.16.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000937 486.0
HFD2_k127_5304585_1 COG2801 Transposase and inactivated derivatives K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003641 271.0
HFD2_k127_5304585_10 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000004302 63.0
HFD2_k127_5304585_2 COG2755 Lysophospholipase L1 and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007208 253.0
HFD2_k127_5304585_3 - - - - 0.0000000000000000000000000000000000000000000001758 173.0
HFD2_k127_5304585_5 -acetyltransferase - - - 0.00000000000000000000000000000000000009988 153.0
HFD2_k127_5304585_6 CAAX protease self-immunity - - - 0.00000000000000000000000000000008276 137.0
HFD2_k127_5304585_7 Alkylmercury lyase K00221 - 4.99.1.2 0.0000000000000000000000000316 117.0
HFD2_k127_5304585_8 Transcriptional regulator - - - 0.000000000000000000001057 101.0
HFD2_k127_5304585_9 transposase activity K07483 - - 0.000000000000000000107 92.0
HFD2_k127_5310131_0 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 436.0
HFD2_k127_5310131_1 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 359.0
HFD2_k127_5310131_2 Converts the aldose L-fucose into the corresponding ketose L-fuculose K01804 - 5.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 286.0
HFD2_k127_5310131_3 response to antibiotic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000167 272.0
HFD2_k127_5310131_4 rhamnose metabolic process K03534 - 5.1.3.32 0.00000000000000000000000000000000000000876 147.0
HFD2_k127_5310131_5 Domain of unknown function (DUF4129) - - - 0.000000000000000003405 95.0
HFD2_k127_5310131_6 - - - - 0.0000000001907 70.0
HFD2_k127_5324185_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.513e-196 622.0
HFD2_k127_5324185_1 PFAM amine oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 477.0
HFD2_k127_5324185_2 Peptidase M16 domain protein K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 322.0
HFD2_k127_5324185_3 PFAM conserved K07027 - - 0.0000000000000000000003138 98.0
HFD2_k127_5327902_0 trehalohydrolase K01236 - 3.2.1.141 2.657e-218 685.0
HFD2_k127_5327902_1 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000105 219.0
HFD2_k127_5327902_2 trehalohydrolase K01236 - 3.2.1.141 0.00000000000000000000000000000000000000000000000000001308 192.0
HFD2_k127_5327902_4 Ig-like domain from next to BRCA1 gene - - - 0.0000000000000000000006985 105.0
HFD2_k127_5337152_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 590.0
HFD2_k127_5337152_1 Polysaccharide biosynthesis protein K15894 - 4.2.1.115 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 519.0
HFD2_k127_5337152_10 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000005219 91.0
HFD2_k127_5337152_2 CoA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 422.0
HFD2_k127_5337152_3 ABC transporter transmembrane region K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009693 347.0
HFD2_k127_5337152_4 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000005758 222.0
HFD2_k127_5337152_5 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000001781 185.0
HFD2_k127_5337152_6 Participates in transcription elongation, termination and antitermination K02601,K05785 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000002346 151.0
HFD2_k127_5337152_7 PFAM Exonuclease, RNase T and DNA polymerase III K02342,K03722 - 2.7.7.7,3.6.4.12 0.0000000000000000000000000000000000005575 143.0
HFD2_k127_5337152_8 Tetratricopeptide repeat - - - 0.0000000000000000000000000227 123.0
HFD2_k127_5337152_9 Tpr repeat-containing protein - - - 0.00000000000000000000001558 104.0
HFD2_k127_533796_0 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000007485 269.0
HFD2_k127_533796_1 Protein of unknown function DUF89 - - - 0.000000000000000000000000000000000000000000000004731 180.0
HFD2_k127_533796_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000004289 111.0
HFD2_k127_5341667_0 transmembrane transport K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17242,K17312,K17316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 299.0
HFD2_k127_5341667_1 glycerophosphodiester transmembrane transport K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001702 283.0
HFD2_k127_5341667_2 glycoside hydrolase family 37 - - - 0.0000000000000000000000000009516 121.0
HFD2_k127_5350602_0 gluconolactonase activity K14274 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 579.0
HFD2_k127_5350602_1 Protein of unknown function (DUF4127) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 509.0
HFD2_k127_5350602_10 transcriptional K03710 - - 0.000000000000000000000000000000000000000000000000003933 192.0
HFD2_k127_5350602_11 Belongs to the HAD-like hydrolase superfamily K02566 - - 0.0000000000000000000000000000000000000000001095 169.0
HFD2_k127_5350602_12 cheY-homologous receiver domain - - - 0.0000017 50.0
HFD2_k127_5350602_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 445.0
HFD2_k127_5350602_3 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 387.0
HFD2_k127_5350602_4 xylulokinase activity K00851,K00854 - 2.7.1.12,2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 394.0
HFD2_k127_5350602_5 COGs COG0395 ABC-type sugar transport system permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 326.0
HFD2_k127_5350602_6 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008787 251.0
HFD2_k127_5350602_7 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) K01788 - 5.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000001959 234.0
HFD2_k127_5350602_8 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000007976 232.0
HFD2_k127_5350602_9 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000005675 205.0
HFD2_k127_535672_0 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000001162 162.0
HFD2_k127_535672_1 Electron transfer DM13 - - - 0.0000000000004046 78.0
HFD2_k127_535672_2 metal ion binding - - - 0.0002146 51.0
HFD2_k127_5357754_0 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 449.0
HFD2_k127_5357754_1 Beta-xylanase K01181 - 3.2.1.8 0.000000000000000000000000000000000000000000000000002655 188.0
HFD2_k127_5369515_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 496.0
HFD2_k127_5369515_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007837 486.0
HFD2_k127_5369515_2 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005271 401.0
HFD2_k127_5369841_0 xanthine dehydrogenase, a b hammerhead - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 555.0
HFD2_k127_5369841_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 325.0
HFD2_k127_5369841_10 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000001156 159.0
HFD2_k127_5369841_11 - - - - 0.000000000000000000000000000000000000009012 149.0
HFD2_k127_5369841_12 family transcriptional regulator - - - 0.0000000000000000000000000000001818 129.0
HFD2_k127_5369841_13 REDY-like protein HapK - - - 0.000002366 57.0
HFD2_k127_5369841_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 318.0
HFD2_k127_5369841_3 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 308.0
HFD2_k127_5369841_4 N-terminal TM domain of oligopeptide transport permease C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 287.0
HFD2_k127_5369841_5 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001347 295.0
HFD2_k127_5369841_6 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000006677 227.0
HFD2_k127_5369841_7 Protein of unknown function (DUF917) K09703 - - 0.0000000000000000000000000000000000000000000000000000000000192 220.0
HFD2_k127_5369841_8 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000006022 217.0
HFD2_k127_5369841_9 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.0000000000000000000000000000000000000000000000002081 183.0
HFD2_k127_5374843_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000004076 233.0
HFD2_k127_5374843_1 Transcriptional regulatory protein, C terminal K02483,K13584 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000004289 81.0
HFD2_k127_5375192_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.053e-260 820.0
HFD2_k127_5375192_1 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000009639 150.0
HFD2_k127_5375192_2 Bacterial regulatory proteins, crp family - - - 0.00000000000000000000004192 102.0
HFD2_k127_5380552_0 hydrolase activity, hydrolyzing O-glycosyl compounds K00689 GO:0005575,GO:0005576 2.4.1.5 2.139e-235 739.0
HFD2_k127_5380552_1 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 497.0
HFD2_k127_5380552_2 helix_turn _helix lactose operon repressor K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 465.0
HFD2_k127_5380552_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 293.0
HFD2_k127_5380552_4 - - - - 0.00000000000000000000000000000000000000000000000002466 197.0
HFD2_k127_5380552_5 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000021 178.0
HFD2_k127_5380552_6 enterobactin catabolic process K07214 - - 0.000000000000000000000000000000008318 138.0
HFD2_k127_5429819_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.215e-225 714.0
HFD2_k127_5429819_1 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000009277 267.0
HFD2_k127_5429819_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000003715 227.0
HFD2_k127_5429819_3 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000009965 222.0
HFD2_k127_5429819_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000001072 98.0
HFD2_k127_5429819_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000001986 78.0
HFD2_k127_5442899_0 ATPase domain of DNA mismatch repair MUTS family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007393 454.0
HFD2_k127_5442899_1 Aldo Keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 420.0
HFD2_k127_5442899_2 B-1 B cell differentiation K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 361.0
HFD2_k127_5442899_3 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000002501 193.0
HFD2_k127_5442899_4 - - - - 0.0000000000000000000000000000000000000000001422 171.0
HFD2_k127_5442899_5 translation initiation factor activity - - - 0.00000000000000000000000000000002833 139.0
HFD2_k127_5442899_6 Pkd domain containing protein - - - 0.000000000000000000000000000001658 141.0
HFD2_k127_5442899_8 protein).. Source PGD - - - 0.0000000003096 72.0
HFD2_k127_5442899_9 Transposase and inactivated derivatives - - - 0.00000001307 60.0
HFD2_k127_5451088_0 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 488.0
HFD2_k127_5451088_1 transposition K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 374.0
HFD2_k127_5451088_2 protein containing SIS (Sugar ISomerase) phosphosugar binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000276 251.0
HFD2_k127_5451088_3 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000003212 199.0
HFD2_k127_5451088_4 transcriptional K03710 - - 0.0000000000000000000000000000000000000000003329 169.0
HFD2_k127_5451088_5 - - - - 0.000000000000000337 83.0
HFD2_k127_5452356_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000008944 166.0
HFD2_k127_5454483_0 arsenite transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 612.0
HFD2_k127_5454483_1 Integrase, catalytic region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 391.0
HFD2_k127_5459310_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 412.0
HFD2_k127_5459310_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002891 273.0
HFD2_k127_5459310_10 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000125 64.0
HFD2_k127_5459310_2 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000003283 206.0
HFD2_k127_5459310_3 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000004121 205.0
HFD2_k127_5459310_4 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000007209 191.0
HFD2_k127_5459310_5 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000001667 163.0
HFD2_k127_5459310_6 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000002316 120.0
HFD2_k127_5459310_7 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000001731 109.0
HFD2_k127_5459310_8 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000001536 96.0
HFD2_k127_5459310_9 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000002902 61.0
HFD2_k127_5468175_0 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000002813 159.0
HFD2_k127_5468175_1 Phosphoesterase family - - - 0.000000000000000000000000000000001007 134.0
HFD2_k127_5468175_2 Transcription factor zinc-finger K09981 - - 0.00000000000006245 77.0
HFD2_k127_5474639_0 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol K01740 - 2.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 582.0
HFD2_k127_5474639_1 Nitrite and sulphite reductase 4Fe-4S K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009558 497.0
HFD2_k127_5474639_2 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000003337 255.0
HFD2_k127_5474639_3 Siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000007091 147.0
HFD2_k127_5474639_4 Pfam:Pyridox_oxidase - - - 0.0000000001231 67.0
HFD2_k127_547860_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000997 332.0
HFD2_k127_547860_1 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 293.0
HFD2_k127_547860_2 glycoside hydrolase family 2, TIM barrel K01192 - 3.2.1.25 0.00000000000000000000000000000000000000000000000000000000000000001184 247.0
HFD2_k127_547860_3 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000271 57.0
HFD2_k127_5485015_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K09181 - - 0.0 1358.0
HFD2_k127_5485015_1 Nickel-dependent hydrogenase - - - 1.155e-208 661.0
HFD2_k127_5485015_2 coenzyme F420 hydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 390.0
HFD2_k127_5485015_3 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 376.0
HFD2_k127_5485015_4 cyclic nucleotide binding K10914 - - 0.000000000000000000000000000000000000000000000000000000000002017 212.0
HFD2_k127_5485015_5 Aldo/keto reductase family K16950 - - 0.00000000000000000000000000000000000000000000000000000000002585 206.0
HFD2_k127_5485015_6 Hydrogenase maturation protease - - - 0.000000000000000000000000000000000000004082 151.0
HFD2_k127_5496302_0 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009308 295.0
HFD2_k127_5496302_1 TIGRFAM small GTP-binding protein K06945 - - 0.0000000000000000000000000000000000000000000000000000000005029 202.0
HFD2_k127_5496302_2 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000000000002669 166.0
HFD2_k127_5496302_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000004982 106.0
HFD2_k127_5525431_0 transferase activity, transferring glycosyl groups K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007397 270.0
HFD2_k127_5525431_1 - - - - 0.0000000000000000000000000000000000000000000000000000000008949 209.0
HFD2_k127_5525431_2 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000001296 154.0
HFD2_k127_5525431_3 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000001249 119.0
HFD2_k127_5540250_0 LysM domain K03046,K03641,K08642 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 361.0
HFD2_k127_5540250_1 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009222 305.0
HFD2_k127_5540250_2 PFAM Glycoside hydrolase, family 13 - - - 0.0000000000000000000000000006349 116.0
HFD2_k127_5546294_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 475.0
HFD2_k127_5546294_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 308.0
HFD2_k127_5546294_2 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 295.0
HFD2_k127_5546294_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001182 258.0
HFD2_k127_5546294_4 Iron-containing alcohol dehydrogenase K00217 - 1.3.1.32 0.00000000000000000000000000000000000000000000000000000000000002894 229.0
HFD2_k127_5546294_5 PFAM lipopolysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000006932 220.0
HFD2_k127_5546294_6 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000824 167.0
HFD2_k127_5546294_7 helix_turn_helix multiple antibiotic resistance protein K15973 - - 0.000000000000000000000000000000000000000001048 160.0
HFD2_k127_5546294_8 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000002085 118.0
HFD2_k127_5546294_9 - - - - 0.00000000000000000001779 101.0
HFD2_k127_5546420_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 1.37e-234 754.0
HFD2_k127_5546420_1 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 541.0
HFD2_k127_5546420_2 COG0477 Permeases of the major facilitator superfamily K08153 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 304.0
HFD2_k127_5546420_3 DMSO reductase anchor subunit (DmsC) K07308 - - 0.00000000000000000000000000000000000000000000000000003348 197.0
HFD2_k127_5546420_4 Nitrate reductase delta subunit - - - 0.0000000000000000000000000000000000003734 149.0
HFD2_k127_5546420_5 4Fe-4S binding domain - - - 0.0000000000000001747 92.0
HFD2_k127_5546420_6 - - - - 0.000000000001458 71.0
HFD2_k127_5559810_0 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002856 279.0
HFD2_k127_5559810_1 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001598 251.0
HFD2_k127_5559810_2 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.000000000000000000000000000000000000000000000000001275 194.0
HFD2_k127_5559810_3 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000002221 184.0
HFD2_k127_5559810_4 protein kinase activity - - - 0.000000000006116 76.0
HFD2_k127_5559810_5 Carbohydrate family 9 binding domain-like - - - 0.0000002606 61.0
HFD2_k127_5561455_0 ABC transporter, transmembrane region K06147,K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 492.0
HFD2_k127_5561455_1 PFAM ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008858 421.0
HFD2_k127_5561455_2 Hydrogenase expression formation protein (HypE) K04655 - - 0.000001235 51.0
HFD2_k127_5569786_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 478.0
HFD2_k127_5569786_1 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 396.0
HFD2_k127_5569786_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.00000000000000000000007129 104.0
HFD2_k127_5574107_0 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 418.0
HFD2_k127_5574107_1 Di-haem oxidoreductase, putative peroxidase K01201 - 3.2.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 371.0
HFD2_k127_5574107_2 Di-haem oxidoreductase, putative peroxidase - - - 0.00000000006003 71.0
HFD2_k127_557493_0 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000848 293.0
HFD2_k127_557493_1 ABC-type dipeptide transport system periplasmic component K02035,K15580 - - 0.0000001356 58.0
HFD2_k127_5579621_0 PFAM glycoside hydrolase clan GH-D K07407 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 592.0
HFD2_k127_5579621_1 S-adenosylhomocysteine deaminase activity K01487 - 3.5.4.3 0.000000000000000000000000000000000000000000000000000000000000001107 227.0
HFD2_k127_5579621_2 cog cog0265 K08372 - - 0.0002773 52.0
HFD2_k127_5580354_0 Phage portal protein - - - 0.000000000000000000000000000000000000000000005649 179.0
HFD2_k127_5580354_1 - - - - 0.0000000000002736 74.0
HFD2_k127_5580354_2 - - - - 0.00001519 55.0
HFD2_k127_5580354_3 Mu-like prophage FluMu protein gp28 - - - 0.00008035 51.0
HFD2_k127_5580966_0 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 425.0
HFD2_k127_5580966_1 WD40 domain protein beta Propeller K03641 - - 0.000000000000000000000000002502 123.0
HFD2_k127_5584983_0 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 484.0
HFD2_k127_5584983_1 Cna B domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 474.0
HFD2_k127_5584983_2 Phosphotriesterase family K07048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 410.0
HFD2_k127_5584983_3 carbohydrate transport K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006924 387.0
HFD2_k127_5584983_4 transmembrane transport K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17242,K17316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 332.0
HFD2_k127_5584983_5 periplasmic binding protein LacI transcriptional regulator K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007429 256.0
HFD2_k127_5584983_6 cheY-homologous receiver domain - - - 0.0000000002792 69.0
HFD2_k127_5584983_7 Histidine kinase - - - 0.00004227 56.0
HFD2_k127_5590268_0 COG0277 FAD FMN-containing dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 541.0
HFD2_k127_5590268_1 phosphatidate phosphatase activity K09474 - 3.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 476.0
HFD2_k127_5590268_2 dihydrofolate reductase activity K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 326.0
HFD2_k127_5590268_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 313.0
HFD2_k127_5590268_4 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000108 267.0
HFD2_k127_5590268_5 Serine threonine protein kinase - - - 0.00000000001197 68.0
HFD2_k127_5598607_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1197.0
HFD2_k127_5598607_1 Glycosyl transferases group 1 - - - 0.0000000000194 70.0
HFD2_k127_5598607_2 transposition - - - 0.0002177 44.0
HFD2_k127_5599362_0 VWA domain containing CoxE-like protein K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005153 545.0
HFD2_k127_5599362_1 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 399.0
HFD2_k127_5599362_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000004367 130.0
HFD2_k127_5599362_11 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000956 118.0
HFD2_k127_5599362_12 Cyclic-di-AMP receptor - - - 0.000000000000000000000001326 106.0
HFD2_k127_5599362_13 Cyclic-di-AMP receptor - - - 0.000000000001865 70.0
HFD2_k127_5599362_2 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009449 406.0
HFD2_k127_5599362_3 PFAM Myo-inositol catabolism IolB domain protein K03337 - 5.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005856 360.0
HFD2_k127_5599362_4 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 304.0
HFD2_k127_5599362_5 Histidine kinase K02484,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 325.0
HFD2_k127_5599362_6 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 295.0
HFD2_k127_5599362_7 Arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000005601 220.0
HFD2_k127_5599362_8 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000357 199.0
HFD2_k127_5599362_9 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000005296 170.0
HFD2_k127_5603400_0 Dak1 domain K05878 - 2.7.1.121 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 481.0
HFD2_k127_5603400_1 xylulokinase activity K00848,K00851,K00854,K00862 - 2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 473.0
HFD2_k127_5603400_2 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 357.0
HFD2_k127_5603400_3 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000006678 233.0
HFD2_k127_5603400_4 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001244 219.0
HFD2_k127_5603400_5 Dak1 domain K05878 - 2.7.1.121 0.000000000000000000000000000000000000000000000000000000003168 206.0
HFD2_k127_5603400_6 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000001007 170.0
HFD2_k127_5603400_7 Iron dependent repressor, N-terminal DNA binding domain - - - 0.00000000000000000000000000000284 124.0
HFD2_k127_5603400_8 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.00000000000000005256 84.0
HFD2_k127_560845_0 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 429.0
HFD2_k127_560845_1 Belongs to the LDH2 MDH2 oxidoreductase family K08092 - 1.1.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 374.0
HFD2_k127_560845_2 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate K01815 - 5.3.1.17 0.00000000000000000000000000000000000000000000000000000000003505 211.0
HFD2_k127_5611215_0 beta-galactosidase activity K01192 - 3.2.1.25 7.707e-261 828.0
HFD2_k127_5611215_1 Binding-protein-dependent transport system inner membrane component K15581 - - 0.000000000000000000000000000000000000000000000000000000001431 216.0
HFD2_k127_5611215_2 ATPase involved in DNA repair K02057,K03546 - - 0.0000000000000000001586 98.0
HFD2_k127_5611215_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000001426 52.0
HFD2_k127_5611215_4 - - - - 0.0001581 52.0
HFD2_k127_5618853_0 Berberine and berberine like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 584.0
HFD2_k127_5618853_1 COG2801 Transposase and inactivated derivatives K07497 - - 0.000000000000000000000000000000000000000007061 159.0
HFD2_k127_5618853_2 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000147 147.0
HFD2_k127_5618853_3 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000002071 114.0
HFD2_k127_5618853_4 PFAM Integrase, catalytic core K07497 - - 0.000000000000000000000004776 106.0
HFD2_k127_5618853_5 Transposase K07483 - - 0.000000000000000005738 87.0
HFD2_k127_5618853_6 Transcriptional regulator - - - 0.00000000000000112 80.0
HFD2_k127_5618853_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000002525 55.0
HFD2_k127_5618853_8 Integrase core domain - - - 0.00000003429 63.0
HFD2_k127_5618853_9 Zinc-binding dehydrogenase - - - 0.0000893 47.0
HFD2_k127_561989_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 2.935e-219 709.0
HFD2_k127_561989_1 Phosphoesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 531.0
HFD2_k127_561989_10 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000008034 104.0
HFD2_k127_561989_11 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.00000008929 53.0
HFD2_k127_561989_2 AntiSigma factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001374 279.0
HFD2_k127_561989_3 Uracil DNA glycosylase superfamily K03649 - 3.2.2.28 0.00000000000000000000000000000000000000000000000000000000000000000001016 238.0
HFD2_k127_561989_4 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000000315 213.0
HFD2_k127_561989_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000006926 191.0
HFD2_k127_561989_6 PFAM DegV family protein - - - 0.000000000000000000000000000000000000000000000000319 186.0
HFD2_k127_561989_7 lipid binding - - - 0.00000000000000000000000000000000000000000000007679 180.0
HFD2_k127_561989_8 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.0000000000000000000000000000000000000001086 157.0
HFD2_k127_561989_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000005764 156.0
HFD2_k127_5625346_0 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 355.0
HFD2_k127_5625346_1 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 336.0
HFD2_k127_5625346_2 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 319.0
HFD2_k127_5625346_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006113 283.0
HFD2_k127_5625346_4 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000006987 239.0
HFD2_k127_5625346_5 ferrous iron binding K06990,K09141 - - 0.00000000000000000000000000000000000000000001789 169.0
HFD2_k127_5625346_6 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000001164 147.0
HFD2_k127_5625346_7 to be involved in DNA repair (RAMP superfamily) - - - 0.00000000000000000002244 97.0
HFD2_k127_5625346_8 Type IV pilus biogenesis stability protein PilW - - - 0.000000005429 67.0
HFD2_k127_5625346_9 crispr-associated protein - - - 0.00007223 55.0
HFD2_k127_5667893_0 PFAM Integrase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 436.0
HFD2_k127_5667893_1 PFAM IstB domain protein ATP-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 326.0
HFD2_k127_5667893_3 - - - - 0.00000000002333 70.0
HFD2_k127_5667893_4 - - - - 0.000004739 52.0
HFD2_k127_5677398_0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000001771 170.0
HFD2_k127_5677398_1 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.000000000000000000000000000000000000000000008169 170.0
HFD2_k127_5693963_0 protein histidine kinase activity K10819 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 347.0
HFD2_k127_5693963_1 NTF2-like N-terminal transpeptidase domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 344.0
HFD2_k127_5693963_10 Short C-terminal domain - - - 0.000002709 52.0
HFD2_k127_5693963_2 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005012 259.0
HFD2_k127_5693963_3 SPTR Q2LSA8 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001659 258.0
HFD2_k127_5693963_4 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000000000000000000000000001323 168.0
HFD2_k127_5693963_5 SPTR B0JN73 Transposase - - - 0.00000000000000000000000000000000000000008415 156.0
HFD2_k127_5693963_6 PFAM Peptidase family M23 - - - 0.00000000000000000000000000000000001729 147.0
HFD2_k127_5693963_7 protein conserved in bacteria - - - 0.0000000000000000000000000000005702 135.0
HFD2_k127_5693963_8 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000000003504 108.0
HFD2_k127_5693963_9 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000005913 104.0
HFD2_k127_5696161_0 membrane K13277,K15125,K15539 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 599.0
HFD2_k127_5728184_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 421.0
HFD2_k127_5728184_1 Penicillin-binding Protein dimerisation domain K03587,K08384 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 372.0
HFD2_k127_5728184_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 312.0
HFD2_k127_5728184_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000105 280.0
HFD2_k127_5735386_0 PFAM Amidohydrolase 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 453.0
HFD2_k127_5735386_1 ATPases associated with a variety of cellular activities K01990,K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 399.0
HFD2_k127_5735386_2 COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 354.0
HFD2_k127_5735386_3 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000002766 231.0
HFD2_k127_5735386_4 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA - - - 0.0000000000000000000000000000000000000000000000004897 186.0
HFD2_k127_5735386_5 PFAM Forkhead-associated protein - - - 0.00005216 52.0
HFD2_k127_5735526_0 NTF2-like N-terminal transpeptidase domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 367.0
HFD2_k127_5735526_1 Encoded by - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007955 261.0
HFD2_k127_5735926_0 heme-copper terminal oxidase activity K02274 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 517.0
HFD2_k127_5735926_1 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000939 412.0
HFD2_k127_5735926_2 Transglycosylase associated protein - - - 0.0000000000000000000000000000003483 124.0
HFD2_k127_5736416_0 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 565.0
HFD2_k127_5736416_1 N-terminal domain of oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 306.0
HFD2_k127_5736416_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000008153 191.0
HFD2_k127_5736416_3 phosphorelay signal transduction system - - - 0.00000000000000000000000005924 126.0
HFD2_k127_5759282_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 1.561e-254 798.0
HFD2_k127_5759282_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 489.0
HFD2_k127_5759282_2 FCD domain - - - 0.0000000000000000000000000000000000000000000000000000000000003585 218.0
HFD2_k127_5759282_3 Lysin motif - - - 0.000000000000000000000000000000000002494 149.0
HFD2_k127_576831_0 heat shock protein 70 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005855 357.0
HFD2_k127_576831_1 E-Z type HEAT repeats K00239 - 1.3.5.1,1.3.5.4 0.0006154 51.0
HFD2_k127_5769598_0 Two component transcriptional regulator, winged helix family K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001924 269.0
HFD2_k127_5769598_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000002896 209.0
HFD2_k127_5769598_2 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000008204 154.0
HFD2_k127_5769598_3 Peptidase family S58 - - - 0.0000000000000000000000000000000000001424 147.0
HFD2_k127_5774013_0 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 296.0
HFD2_k127_5774013_1 HWE histidine kinase - - - 0.0000000000000000000000000000000000000000001753 164.0
HFD2_k127_5774013_2 membrane - - - 0.0000000000000000000000000000000000000002973 153.0
HFD2_k127_5789427_0 spore coat K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000005898 180.0
HFD2_k127_5789427_1 Transposase - - - 0.0000000000000000169 94.0
HFD2_k127_5789427_2 PFAM Haloacid dehalogenase domain protein hydrolase K05306 - 3.11.1.1 0.000000000000002689 76.0
HFD2_k127_5789427_3 Transposase - - - 0.0000000002919 64.0
HFD2_k127_5791784_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 299.0
HFD2_k127_5791784_1 MFS_1 like family K08151,K08153 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004952 260.0
HFD2_k127_5791784_2 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.000000000000000000000000000000000000000000000000000000001791 211.0
HFD2_k127_5791784_3 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000001247 156.0
HFD2_k127_5791784_4 response to abiotic stimulus K01971,K03086,K06867,K06886 GO:0003674,GO:0003779,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006996,GO:0007010,GO:0007015,GO:0008092,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030029,GO:0030036,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044877,GO:0046983,GO:0051015,GO:0051259,GO:0065003,GO:0071840,GO:0097435 6.5.1.1 0.000000000000000000000000000000000000132 148.0
HFD2_k127_5791784_5 RNA recognition motif - - - 0.000000000000000000000000004455 115.0
HFD2_k127_5791784_6 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000006042 115.0
HFD2_k127_5791784_7 2'-5' RNA ligase superfamily - - - 0.0000000000000000002341 95.0
HFD2_k127_5791784_8 - - - - 0.00000000002364 71.0
HFD2_k127_5798677_0 peptidase dimerisation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007896 388.0
HFD2_k127_5798677_1 Protein of unknown function (DUF2723) - - - 0.000000000000006605 89.0
HFD2_k127_5798677_2 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0002207 45.0
HFD2_k127_5799483_0 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000002973 216.0
HFD2_k127_580937_0 ABC transporter K10562 - 3.6.3.17 3.852e-205 649.0
HFD2_k127_580937_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 507.0
HFD2_k127_580937_10 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 336.0
HFD2_k127_580937_11 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 293.0
HFD2_k127_580937_12 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001133 272.0
HFD2_k127_580937_13 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004274 290.0
HFD2_k127_580937_14 PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006679 269.0
HFD2_k127_580937_15 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000003349 198.0
HFD2_k127_580937_16 Domain of unknown function (DUF1905) - - - 0.0000000000000000000000000000000000000000000000000001358 190.0
HFD2_k127_580937_17 Periplasmic binding protein LacI transcriptional regulator K02103,K05499 - - 0.00000000000000000000000000000000000000000003183 176.0
HFD2_k127_580937_18 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000004396 183.0
HFD2_k127_580937_19 (FHA) domain - - - 0.00003297 55.0
HFD2_k127_580937_2 carbohydrate transport K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 493.0
HFD2_k127_580937_3 Monooxygenase fad-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 443.0
HFD2_k127_580937_4 Periplasmic binding protein domain K10559 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 370.0
HFD2_k127_580937_5 TOBE domain K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 353.0
HFD2_k127_580937_6 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008866 346.0
HFD2_k127_580937_7 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 346.0
HFD2_k127_580937_8 Belongs to the binding-protein-dependent transport system permease family K10560 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 343.0
HFD2_k127_580937_9 Belongs to the binding-protein-dependent transport system permease family K10561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 343.0
HFD2_k127_5813540_0 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000000000000000000000000009072 166.0
HFD2_k127_5813540_1 Thioredoxin - - - 0.00000000000000000000000000000000000000002828 160.0
HFD2_k127_5813540_2 Thioredoxin-like - - - 0.00000000000000000000000000000000002811 143.0
HFD2_k127_5822116_0 TIGRFAM capsular exopolysaccharide family K08253 - 2.7.10.2 0.0000000000000000000000000000000000000000000000000000000000000000001698 236.0
HFD2_k127_5822116_1 - - - - 0.000000000000000000000000000000000007997 139.0
HFD2_k127_5822116_2 PFAM lipopolysaccharide biosynthesis protein - - - 0.000000000000000000000000005774 118.0
HFD2_k127_5822116_3 PFAM HD domain K06950 - - 0.0000000000000001622 89.0
HFD2_k127_5843734_0 HIT domain - - - 0.00000000000000000000000000000000000000000000000000003656 192.0
HFD2_k127_5843734_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000002458 183.0
HFD2_k127_5843734_2 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000000000000000000000009964 145.0
HFD2_k127_5843734_3 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000001435 132.0
HFD2_k127_5843734_4 translation initiation factor activity - - - 0.0000000000000000001539 92.0
HFD2_k127_5843734_5 PFAM Major Facilitator Superfamily - - - 0.0000001172 58.0
HFD2_k127_5857047_0 L-glutamate biosynthetic process K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 6.411e-242 767.0
HFD2_k127_5865956_0 MBOAT, membrane-bound O-acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000008057 210.0
HFD2_k127_5876875_0 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 594.0
HFD2_k127_5876875_1 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 321.0
HFD2_k127_5876875_2 Voltage gated chloride channel - - - 0.000000000000000000000000000000000000000000000000000000000001602 215.0
HFD2_k127_5876875_3 amino acid-binding ACT domain protein K04767 - - 0.000000000000000000000000000000000000000000000007 179.0
HFD2_k127_5876875_5 PFAM DSBA oxidoreductase - - - 0.000000001632 68.0
HFD2_k127_5886160_0 Stage II sporulation K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 430.0
HFD2_k127_5886160_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006674 381.0
HFD2_k127_5886160_10 - - - - 0.00000000000000001039 87.0
HFD2_k127_5886160_11 COG3764 Sortase (surface protein transpeptidase) K07284 - 3.4.22.70 0.000000008349 65.0
HFD2_k127_5886160_12 4-amino-4-deoxy-L-arabinose transferase activity K13687 - - 0.00000009861 63.0
HFD2_k127_5886160_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000233 243.0
HFD2_k127_5886160_3 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000004734 220.0
HFD2_k127_5886160_4 Putative threonine/serine exporter - - - 0.00000000000000000000000000000000000000000000000001593 190.0
HFD2_k127_5886160_5 PHP-associated - - - 0.0000000000000000000000000000000000000000000000004971 185.0
HFD2_k127_5886160_6 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000000000000000007747 175.0
HFD2_k127_5886160_7 response to peptide - - - 0.0000000000000000000000000000000000000001148 154.0
HFD2_k127_5886160_8 Histidine kinase - - - 0.0000000000000000000000008372 108.0
HFD2_k127_5886160_9 Regulatory protein, FmdB family - - - 0.000000000000000000001072 98.0
HFD2_k127_5902941_0 Asparagine synthase K01953 - 6.3.5.4 2.294e-269 845.0
HFD2_k127_5902941_1 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 519.0
HFD2_k127_5902941_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 436.0
HFD2_k127_5902941_3 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000002724 230.0
HFD2_k127_5902941_4 O-acyltransferase activity - - - 0.00000000000000000000000000000000000000000000000001129 185.0
HFD2_k127_5902941_5 methyltransferase - - - 0.00000000000000000000000000002037 128.0
HFD2_k127_5902941_6 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.0000000000000000000000000002268 129.0
HFD2_k127_5902941_7 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000793 93.0
HFD2_k127_5902941_8 PFAM Forkhead-associated protein - - - 0.00000000000002572 81.0
HFD2_k127_5902941_9 - - - - 0.0000000007393 73.0
HFD2_k127_5905949_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000593 216.0
HFD2_k127_5905949_1 4Fe-4S binding domain K00184 - - 0.0000000000000000000000000000000000000000000000000001254 198.0
HFD2_k127_5905949_2 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000000000000000008552 189.0
HFD2_k127_5914690_0 Thiamin pyrophosphokinase, vitamin B1 binding domain K00949 - 2.7.6.2 0.00000000000000000000000000000000000000000006937 172.0
HFD2_k127_5914690_1 Thiamine-binding protein - - - 0.0000000000000007306 80.0
HFD2_k127_5914690_2 Binding-protein-dependent transport system inner membrane component - - - 0.0004003 48.0
HFD2_k127_5917480_0 transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 475.0
HFD2_k127_5917480_1 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000002543 101.0
HFD2_k127_5918621_0 Alpha amylase, catalytic domain protein K01208,K11991 - 3.2.1.133,3.2.1.135,3.2.1.54,3.5.4.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000702 593.0
HFD2_k127_5918621_1 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000002951 254.0
HFD2_k127_5918621_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000008046 215.0
HFD2_k127_5918621_3 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000008958 210.0
HFD2_k127_5918621_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257,K02259 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000002362 141.0
HFD2_k127_5918621_5 self proteolysis - - - 0.0000000000000000000000000000004925 134.0
HFD2_k127_5919404_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 1.518e-252 794.0
HFD2_k127_5919404_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006477 238.0
HFD2_k127_5919404_2 YwiC-like protein - - - 0.00000000000000000000000000000000000000000000000004889 187.0
HFD2_k127_5919404_3 Cyclic nucleotide-monophosphate binding domain K21564 - - 0.0000000000000000000000000000000000000000002165 167.0
HFD2_k127_5919404_4 positive regulation of transcription, DNA-templated K09684 - - 0.000000000000000000000000000002324 130.0
HFD2_k127_5919404_5 HNH endonuclease K07451 - - 0.000000000000000000006134 96.0
HFD2_k127_5919404_6 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000009067 98.0
HFD2_k127_5919404_9 - - - - 0.00003167 49.0
HFD2_k127_592242_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 486.0
HFD2_k127_592242_1 S-acyltransferase activity K00627,K00658 - 2.3.1.12,2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005054 481.0
HFD2_k127_592242_10 Protein of unknown function, DUF624 - - - 0.0000002046 61.0
HFD2_k127_592242_2 Metallopeptidase family M24 K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 353.0
HFD2_k127_592242_3 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 304.0
HFD2_k127_592242_4 DeoR C terminal sensor domain K02081 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 290.0
HFD2_k127_592242_5 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K00162,K11381 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000002933 223.0
HFD2_k127_592242_6 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000227 211.0
HFD2_k127_592242_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000006408 196.0
HFD2_k127_592242_9 Cell Wall K01448 - 3.5.1.28 0.00000000000008981 83.0
HFD2_k127_5926547_0 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000001476 211.0
HFD2_k127_5926547_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000001033 167.0
HFD2_k127_5926547_2 methyltransferase activity K00563,K13307,K13330,K15256 - 2.1.1.187,2.1.1.235,2.1.1.324 0.00000000000000000000000000000000000000004507 160.0
HFD2_k127_5926547_3 Transcription factor zinc-finger - - - 0.0000003937 58.0
HFD2_k127_5940473_0 Lycopene cyclase protein K06443 - 5.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 408.0
HFD2_k127_5940473_1 beta-glucosidase activity K05350,K21000 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 387.0
HFD2_k127_5940473_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 346.0
HFD2_k127_5940473_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 330.0
HFD2_k127_5940473_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000001462 251.0
HFD2_k127_5940473_5 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000303 252.0
HFD2_k127_5940473_6 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798,K04076,K17681 - 3.4.21.53 0.000000000000000000000000000000001708 144.0
HFD2_k127_5946062_0 TIR domain - - - 0.0000003636 63.0
HFD2_k127_5946062_1 WD domain, G-beta repeat K12132 - 2.7.11.1 0.0002234 53.0
HFD2_k127_5947099_0 PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - 1.176e-220 698.0
HFD2_k127_5947099_1 ABC transporter, ATP-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 489.0
HFD2_k127_5947099_2 PFAM Phosphomethylpyrimidine kinase type-1 K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000005333 198.0
HFD2_k127_5947099_3 GUN4-like - - - 0.00000000000000000000003578 111.0
HFD2_k127_595717_0 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 411.0
HFD2_k127_595717_1 transcriptional regulator - - - 0.0000002157 54.0
HFD2_k127_595717_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000703 58.0
HFD2_k127_5957492_0 helix_turn_helix, Lux Regulon K03556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 519.0
HFD2_k127_5957492_1 EamA-like transporter family K11939 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 301.0
HFD2_k127_5957492_2 - - - - 0.00000000000000000000000000000000000001143 148.0
HFD2_k127_5957492_3 Sodium:sulfate symporter transmembrane region - - - 0.00000000000000000000000000000000018 135.0
HFD2_k127_5961889_0 dead DEAH box helicase K17675 - 3.6.4.13 1.213e-206 676.0
HFD2_k127_5961889_1 cell wall glycoprotein biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009861 520.0
HFD2_k127_5961889_2 aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 438.0
HFD2_k127_5961889_3 COG COG1082 Sugar phosphate isomerases epimerases K18910 - 5.1.3.30,5.1.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007804 391.0
HFD2_k127_5961889_4 Periplasmic binding proteins and sugar binding domain of LacI family K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001127 257.0
HFD2_k127_5961889_5 fucose binding K02431 - 5.1.3.29 0.00000000000000000000000000000000000000000000000009673 182.0
HFD2_k127_5961889_6 phosphorelay signal transduction system - - - 0.0000000000005588 74.0
HFD2_k127_5967216_0 Penicillin amidase K01434 - 3.5.1.11 1.882e-203 661.0
HFD2_k127_5967216_1 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 515.0
HFD2_k127_5967216_10 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000000002134 162.0
HFD2_k127_5967216_11 phosphoprotein phosphatase activity - - - 0.000000000000000000000000000000000000000008112 164.0
HFD2_k127_5967216_12 GAF domain - - - 0.000000000000000000000000000000000002184 150.0
HFD2_k127_5967216_13 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000002122 60.0
HFD2_k127_5967216_14 Forkhead associated domain - - - 0.000004236 60.0
HFD2_k127_5967216_15 - - - - 0.0001181 52.0
HFD2_k127_5967216_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 496.0
HFD2_k127_5967216_3 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 493.0
HFD2_k127_5967216_4 PHP domain protein K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 463.0
HFD2_k127_5967216_5 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 406.0
HFD2_k127_5967216_6 Calcineurin-like phosphoesterase K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 332.0
HFD2_k127_5967216_7 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002895 270.0
HFD2_k127_5967216_8 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000000000000008882 175.0
HFD2_k127_5967216_9 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000002406 174.0
HFD2_k127_596747_0 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 399.0
HFD2_k127_596747_1 ABC-type dipeptide transport system periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001784 265.0
HFD2_k127_596747_2 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.000000000001698 79.0
HFD2_k127_596747_3 - - - - 0.0003547 53.0
HFD2_k127_5969793_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001166 293.0
HFD2_k127_5969793_1 Peptidase_C39 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000399 245.0
HFD2_k127_5969793_2 Peptidase_C39 like family - - - 0.0000000000000000000000000000000000000000000000000000000000002321 230.0
HFD2_k127_5969793_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000413 53.0
HFD2_k127_5970916_0 Aldehyde dehydrogenase family K13877 - 1.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005735 479.0
HFD2_k127_5970916_1 ATPases associated with a variety of cellular activities K02028,K02030,K09972 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000636 389.0
HFD2_k127_5970916_2 Peptidase family U32 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 381.0
HFD2_k127_5970916_3 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001689 262.0
HFD2_k127_5970916_4 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K09971 - - 0.000000000000000000000000000000000000000000000000000001366 199.0
HFD2_k127_5970916_5 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000000000000000449 151.0
HFD2_k127_5985694_0 Polysaccharide biosynthesis protein - - - 4.775e-275 895.0
HFD2_k127_5985694_1 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007396 534.0
HFD2_k127_5985694_2 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 308.0
HFD2_k127_5985694_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000002043 87.0
HFD2_k127_5985694_4 amine dehydrogenase activity K08884 - 2.7.11.1 0.00000008818 64.0
HFD2_k127_5993053_0 Carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000001862 218.0
HFD2_k127_5993053_1 - - - - 0.000000000000000000000000000001353 134.0
HFD2_k127_5993053_2 pseudouridine synthase activity K06178,K06181,K06183 - 5.4.99.19,5.4.99.20,5.4.99.22 0.00000000000002778 87.0
HFD2_k127_599403_0 PhoQ Sensor - - - 0.0000000000003258 82.0
HFD2_k127_5995357_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000594 383.0
HFD2_k127_5995357_1 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001069 273.0
HFD2_k127_5995357_2 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004104 280.0
HFD2_k127_5995357_3 Glycosyl transferase family group 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001733 267.0
HFD2_k127_5995357_4 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004223 272.0
HFD2_k127_5995357_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000001075 218.0
HFD2_k127_5995357_6 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000006947 210.0
HFD2_k127_5995357_7 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000002199 211.0
HFD2_k127_5995357_8 Pfam Response regulator receiver K02488 - 2.7.7.65 0.000000000000000001253 90.0
HFD2_k127_5995357_9 GUN4-like - - - 0.0000000000000001715 93.0
HFD2_k127_6004342_0 Domain of unknown function (DUF1929) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009856 377.0
HFD2_k127_6004342_1 Transposase and inactivated derivatives K07486 - - 0.00000000000000000000000000000000000001344 152.0
HFD2_k127_6004342_2 Transposase DDE domain group 1 - - - 0.0000000000000000000000000001699 116.0
HFD2_k127_6004342_3 PFAM transposase, IS4 family protein - - - 0.000000000000000072 84.0
HFD2_k127_6004342_4 Transposase DDE domain - - - 0.000000000004497 70.0
HFD2_k127_6004342_5 Transposase - - - 0.00003714 49.0
HFD2_k127_6004342_6 - K18320 - - 0.00005972 45.0
HFD2_k127_600545_0 PFAM Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 385.0
HFD2_k127_600545_1 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000002877 151.0
HFD2_k127_600545_2 Abhydrolase family - - - 0.0000000000000000000000000000007724 135.0
HFD2_k127_6018252_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02484,K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000007721 249.0
HFD2_k127_6018252_1 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000003485 153.0
HFD2_k127_6022319_0 SIS domain K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 346.0
HFD2_k127_6022319_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000238 201.0
HFD2_k127_6022319_2 WD domain, G-beta repeat K12132 - 2.7.11.1 0.00000829 58.0
HFD2_k127_6022319_3 Competence protein CoiA-like family K06198 - - 0.0005305 48.0
HFD2_k127_6027847_0 Heavy-metal-associated domain K17686 - 3.6.3.54 1.245e-296 924.0
HFD2_k127_6027847_1 carbohydrate transport K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006093 315.0
HFD2_k127_6027847_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000003132 164.0
HFD2_k127_6027847_3 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000001395 170.0
HFD2_k127_6027847_4 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000003569 115.0
HFD2_k127_6027847_5 YceI-like domain - - - 0.000000000000000000001119 97.0
HFD2_k127_6031753_0 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 324.0
HFD2_k127_6031753_1 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000003889 211.0
HFD2_k127_6031753_2 COGs COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog K03088 - - 0.000000000000000000000000003666 114.0
HFD2_k127_6031753_3 WD40-like Beta Propeller Repeat - - - 0.000224 54.0
HFD2_k127_6048905_0 Aldose 1-epimerase K01785 - 5.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008744 469.0
HFD2_k127_6048905_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 397.0
HFD2_k127_6048905_2 Hydrogenase accessory protein HypB K03189,K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 287.0
HFD2_k127_6048905_3 Fructose-1,6-bisphosphate aldolase, class II K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000192 239.0
HFD2_k127_6048905_4 Belongs to the carbohydrate kinase PfkB family. LacC subfamily K00917 - 2.7.1.144 0.0000000000000000000000000000000000000000000000000000000002374 218.0
HFD2_k127_6048905_5 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000000000000000003646 139.0
HFD2_k127_6048905_6 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657,K07658,K18941 - - 0.000000000000000005816 90.0
HFD2_k127_6048905_7 O-linked N-acetylglucosamine transferase - - - 0.00004077 56.0
HFD2_k127_6048905_8 ATPase family associated with various cellular activities (AAA) - - - 0.0002007 52.0
HFD2_k127_6072615_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 368.0
HFD2_k127_6072615_1 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000001593 146.0
HFD2_k127_6072615_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000002168 68.0
HFD2_k127_6076262_0 Belongs to the ClpA ClpB family K03696 - - 3.231e-194 631.0
HFD2_k127_6076262_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001665 284.0
HFD2_k127_6081275_0 metal-dependent phosphohydrolase, HD sub domain K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 424.0
HFD2_k127_608213_0 Bacterial membrane protein YfhO - - - 0.00000000000000000000000000000000000000000000000000000000000000002083 250.0
HFD2_k127_608213_1 COGs COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - 0.000000000000000000000000000000000000000000000002429 178.0
HFD2_k127_608213_2 Psort location Cytoplasmic, score K09707 - - 0.0000000000000000000000000000000000000000001158 163.0
HFD2_k127_608213_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00004022 57.0
HFD2_k127_6086866_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.685e-238 750.0
HFD2_k127_6086866_1 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002615 281.0
HFD2_k127_6086866_2 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000004897 254.0
HFD2_k127_6086866_3 Putative ATPase subunit of terminase (gpP-like) - - - 0.0000000000000000000000000000000000000000000000000000000000000000006567 236.0
HFD2_k127_6086866_4 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633,K07589 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564 1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8 0.000000000000000000000000000000000000000001107 159.0
HFD2_k127_6086866_5 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000002955 137.0
HFD2_k127_6086866_6 PFAM GGDEF domain containing protein - - - 0.0000000000000000001091 93.0
HFD2_k127_6086866_7 Tetratricopeptide repeat - - - 0.00000000008027 74.0
HFD2_k127_6086866_8 peptidase K21471 - - 0.0000000001384 74.0
HFD2_k127_6088806_0 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 332.0
HFD2_k127_6099765_0 hydrolase, family 65, central catalytic K00691 - 2.4.1.8 9.102e-301 939.0
HFD2_k127_6099765_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.058e-264 874.0
HFD2_k127_6099765_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000003187 132.0
HFD2_k127_6099765_11 - - - - 0.0000006176 57.0
HFD2_k127_6099765_12 PFAM VanZ like - - - 0.00000134 55.0
HFD2_k127_6099765_2 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 433.0
HFD2_k127_6099765_3 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 394.0
HFD2_k127_6099765_4 Flavin-binding monooxygenase-like K07222,K18277 - 1.14.13.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 347.0
HFD2_k127_6099765_5 Transport permease protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001099 293.0
HFD2_k127_6099765_7 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000004431 200.0
HFD2_k127_6099765_8 transferase activity, transferring acyl groups K15520 - 2.3.1.189 0.000000000000000000000000000000000000006257 153.0
HFD2_k127_6099765_9 Sulfatase-modifying factor enzyme 1 K18912 - 1.14.99.50 0.000000000000000000000000000000000004233 151.0
HFD2_k127_6102650_0 ATP-dependent peptidase activity K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 427.0
HFD2_k127_6102650_1 PFAM AAA-4 family protein K03655 - 3.6.4.12 0.000000000000000000000000000000000002141 146.0
HFD2_k127_6112287_0 myo-inosose-2 dehydratase activity K21909 - 5.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 354.0
HFD2_k127_6112287_1 MFS_1 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007965 285.0
HFD2_k127_6112287_2 Serine/Threonine protein kinases, catalytic domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000001671 258.0
HFD2_k127_6112287_3 Hypothetical glycosyl hydrolase 6 - - - 0.000000000000000000000000000000000000000000000000000000000000000193 235.0
HFD2_k127_6112287_4 PFAM Exonuclease, RNase T and DNA polymerase III K02342,K03722 - 2.7.7.7,3.6.4.12 0.0000000000000000000000000000000004082 136.0
HFD2_k127_6112287_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000001611 132.0
HFD2_k127_6116580_0 Psort location CytoplasmicMembrane, score K02003 - - 0.0000000000000000000000000000000000000000000000000000000001815 207.0
HFD2_k127_6116580_1 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000000000003013 204.0
HFD2_k127_6116580_3 Major facilitator Superfamily - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015562,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0042891,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0001615 51.0
HFD2_k127_6125557_0 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 510.0
HFD2_k127_6125557_1 Branched-chain amino acid ATP-binding cassette transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 426.0
HFD2_k127_6125557_2 Amino acid amide ABC transporter ATP-binding protein 2, HAAT family K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 385.0
HFD2_k127_6125557_3 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 338.0
HFD2_k127_6125557_4 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.0000000000000000000000000000000000000008877 148.0
HFD2_k127_6146978_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.0 1019.0
HFD2_k127_6146978_1 Orotidine-5-phosphate decarboxylase orotate phosphoribosyltransferase K01591,K13421 - 2.4.2.10,4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 475.0
HFD2_k127_6146978_10 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000001237 205.0
HFD2_k127_6146978_11 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000008336 111.0
HFD2_k127_6146978_12 Protein of unknown function (DUF4012) - - - 0.000000000000000006738 98.0
HFD2_k127_6146978_2 Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase K11540 GO:0000050,GO:0000052,GO:0000166,GO:0001882,GO:0001884,GO:0002119,GO:0002134,GO:0002164,GO:0003674,GO:0003824,GO:0004070,GO:0004087,GO:0004088,GO:0004151,GO:0004672,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006213,GO:0006220,GO:0006221,GO:0006228,GO:0006464,GO:0006468,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007275,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009605,GO:0009653,GO:0009719,GO:0009725,GO:0009791,GO:0009887,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0016053,GO:0016301,GO:0016310,GO:0016363,GO:0016597,GO:0016740,GO:0016741,GO:0016743,GO:0016772,GO:0016773,GO:0016787,GO:0016810,GO:0016812,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0017144,GO:0018107,GO:0018130,GO:0018193,GO:0018210,GO:0019103,GO:0019240,GO:0019438,GO:0019538,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0019899,GO:0022612,GO:0030424,GO:0030554,GO:0031406,GO:0031667,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0032868,GO:0032991,GO:0033267,GO:0034399,GO:0034404,GO:0034641,GO:0034654,GO:0035295,GO:0035639,GO:0036094,GO:0036211,GO:0036477,GO:0042221,GO:0042455,GO:0042594,GO:0042802,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043195,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043434,GO:0043436,GO:0043603,GO:0043604,GO:0043679,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044297,GO:0044306,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044456,GO:0044463,GO:0044464,GO:0045202,GO:0046051,GO:0046112,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046394,GO:0046483,GO:0046777,GO:0046872,GO:0046914,GO:0048513,GO:0048565,GO:0048731,GO:0048732,GO:0048856,GO:0050896,GO:0055086,GO:0055123,GO:0060465,GO:0070013,GO:0070335,GO:0070406,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:0097458,GO:0098793,GO:0120025,GO:0120038,GO:0140096,GO:0150034,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901652,GO:1901657,GO:1901659,GO:1901698,GO:1901700,GO:1905905 2.1.3.2,3.5.2.3,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 409.0
HFD2_k127_6146978_3 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000944 405.0
HFD2_k127_6146978_4 Catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008645 358.0
HFD2_k127_6146978_5 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 334.0
HFD2_k127_6146978_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 327.0
HFD2_k127_6146978_7 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00226,K00254 - 1.3.5.2,1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 319.0
HFD2_k127_6146978_8 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 295.0
HFD2_k127_6146978_9 PFAM lipopolysaccharide biosynthesis protein K08253 - 2.7.10.2 0.000000000000000000000000000000000000000000000000000000000000000229 239.0
HFD2_k127_6153165_0 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688 - 2.4.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 626.0
HFD2_k127_6153165_1 PFAM Bacterial regulatory proteins, lacI family K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 299.0
HFD2_k127_6153165_2 Two component transcriptional regulator, winged helix family K07667,K07668 - - 0.00000000000000000000000000000000000000000000000000000000008997 215.0
HFD2_k127_6153165_3 PFAM extracellular solute-binding protein family 1 K10117 - - 0.00000000000000000000000000000000000000000000000000004409 196.0
HFD2_k127_6153165_4 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000004645 165.0
HFD2_k127_6153165_5 universal stress protein - - - 0.000000000000000000000000000000000004504 149.0
HFD2_k127_6153165_6 Methyltransferase domain - - - 0.0000000000000000000000000000002291 128.0
HFD2_k127_6153165_7 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000005223 67.0
HFD2_k127_6154971_0 Permease K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002531 271.0
HFD2_k127_6154971_1 Psort location CytoplasmicMembrane, score 10.00 K02033,K15581 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000105 253.0
HFD2_k127_6154971_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00001395 55.0
HFD2_k127_6155038_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 396.0
HFD2_k127_6155038_1 glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000000000000008753 159.0
HFD2_k127_6155038_2 SMART tyrosine protein kinase K18912 - 1.14.99.50 0.000000000000000000000000000000000000001057 158.0
HFD2_k127_6155038_3 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000005671 79.0
HFD2_k127_6155038_4 antibiotic catabolic process - - - 0.000000000001466 80.0
HFD2_k127_6155038_5 Calcineurin-like phosphoesterase - - - 0.0001565 52.0
HFD2_k127_6156203_0 WD-40 repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005681 476.0
HFD2_k127_6156203_1 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009701 385.0
HFD2_k127_6156203_2 PFAM conserved K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 311.0
HFD2_k127_6156203_3 PFAM zinc finger, SWIM domain protein - - - 0.00000000000000000000000000001498 121.0
HFD2_k127_6157429_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 1.073e-222 702.0
HFD2_k127_6157429_1 - K09932 - - 0.0000000000000000001077 93.0
HFD2_k127_6162168_0 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008123 390.0
HFD2_k127_6162168_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000001177 211.0
HFD2_k127_6162168_2 cytochrome C - - - 0.000000000000000000000000000000000000000000005443 173.0
HFD2_k127_6162168_3 Histidine kinase K07777 - 2.7.13.3 0.0000000000000000000000000000000000002974 159.0
HFD2_k127_6162168_5 heavy metal translocating P-type ATPase K01533 - 3.6.3.4 0.00000005937 54.0
HFD2_k127_6167642_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 3.119e-271 847.0
HFD2_k127_6167642_1 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000000000131 225.0
HFD2_k127_6167642_2 - - - - 0.0000000000000000000000000000000005318 143.0
HFD2_k127_6167642_3 FecR protein - - - 0.000000000000009035 78.0
HFD2_k127_6187995_0 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 539.0
HFD2_k127_6187995_1 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 495.0
HFD2_k127_6187995_2 SIS domain K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008796 391.0
HFD2_k127_6187995_3 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 378.0
HFD2_k127_6187995_4 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 355.0
HFD2_k127_6187995_5 DeoR C terminal sensor domain K02081 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 301.0
HFD2_k127_6187995_6 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000063 185.0
HFD2_k127_6193922_0 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 554.0
HFD2_k127_6193922_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004458 274.0
HFD2_k127_6193922_2 Mo-molybdopterin cofactor metabolic process K03636 - - 0.000000000000000000000000000000000000000001518 159.0
HFD2_k127_6193922_3 Mo-molybdopterin cofactor metabolic process - - - 0.000000000000000004429 89.0
HFD2_k127_6197641_0 Peptidase family S51 K13282 - 3.4.15.6 0.0000001055 62.0
HFD2_k127_6197641_1 FR47-like protein - - - 0.000002662 57.0
HFD2_k127_6210873_0 COG0515 Serine threonine protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001086 276.0
HFD2_k127_6210873_1 - - - - 0.000000000000000000000000000000000000000000000000000002761 209.0
HFD2_k127_6210873_2 Glyoxalase-like domain - - - 0.00000000000000000000000000000000001124 141.0
HFD2_k127_6214161_0 Family 4 glycosyl hydrolase K01222,K07406 - 3.2.1.22,3.2.1.86 2.235e-218 683.0
HFD2_k127_6214161_1 N-acetylglucosamine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 363.0
HFD2_k127_6214161_2 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion K01057,K02564 - 3.1.1.31,3.5.99.6 0.000000000000000000000000000000000000000000000000000000005038 205.0
HFD2_k127_6215612_0 Polysaccharide pyruvyl transferase K16710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001375 284.0
HFD2_k127_6215612_1 transferase activity, transferring glycosyl groups K07011 - - 0.00000000000000000000000000000000000000000000000000000000001052 221.0
HFD2_k127_6215612_2 UDP-N-acetylglucosamine 2-epimerase activity - - - 0.0000000000000000000000000000000005855 148.0
HFD2_k127_6215612_3 Glycosyltransferase like family 2 - - - 0.0004631 45.0
HFD2_k127_6216066_0 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 463.0
HFD2_k127_6216066_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 349.0
HFD2_k127_6216066_2 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 321.0
HFD2_k127_6216066_3 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 301.0
HFD2_k127_6216066_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000002194 93.0
HFD2_k127_6229933_0 Aldolase K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000000000000000000000000000000004506 239.0
HFD2_k127_6229933_1 Acetyltransferase GNAT family - - - 0.00000000000000000000000000000000000000000000000000000000005268 210.0
HFD2_k127_6229933_2 TIGRFAM small GTP-binding protein K06945 - - 0.00000000000000000000000000000000000000000000005656 175.0
HFD2_k127_6229933_3 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0000000000000000000000000000000000000217 158.0
HFD2_k127_6229933_4 methyltransferase K05928 - 2.1.1.95 0.000000000000000000000000000000009566 139.0
HFD2_k127_6229933_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000001202 102.0
HFD2_k127_6229933_6 YacP-like NYN domain K06962 - - 0.00000000000000007163 88.0
HFD2_k127_6231822_0 Tex-like protein N-terminal domain K06959 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 440.0
HFD2_k127_6231822_1 helix_turn _helix lactose operon repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001555 282.0
HFD2_k127_6235735_0 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 558.0
HFD2_k127_6235735_1 nitrite transmembrane transporter activity K02532 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000098 458.0
HFD2_k127_6235735_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.000000000000000000000000003256 113.0
HFD2_k127_6235735_11 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000007426 111.0
HFD2_k127_6235735_12 PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein K00341 - 1.6.5.3 0.000002317 53.0
HFD2_k127_6235735_2 Phosphotriesterase family K07048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 387.0
HFD2_k127_6235735_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 392.0
HFD2_k127_6235735_4 nitrogen compound transport K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 363.0
HFD2_k127_6235735_5 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 342.0
HFD2_k127_6235735_6 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 317.0
HFD2_k127_6235735_7 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007741 308.0
HFD2_k127_6235735_8 dipeptide transport K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003623 248.0
HFD2_k127_6235735_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.000000000000000000000000000000000000000006398 156.0
HFD2_k127_6255924_0 NUDIX domain K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009277 424.0
HFD2_k127_6255924_1 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002135 276.0
HFD2_k127_6255924_2 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000002477 227.0
HFD2_k127_6255924_3 aminoglycoside K00662 - 2.3.1.81 0.00000000000000000000000000000000000000000000000000000000003593 214.0
HFD2_k127_6255924_4 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000000000006265 157.0
HFD2_k127_6255924_5 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000000000000002188 102.0
HFD2_k127_6256692_0 PFAM Aldehyde dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 599.0
HFD2_k127_6256692_1 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.0000000000000000000000000000000000000000000000000000001449 202.0
HFD2_k127_6256692_2 branched-chain amino acid transport system, permease component K01998 - - 0.0000000000000000000000000000000000000000001144 169.0
HFD2_k127_6256692_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000001346 131.0
HFD2_k127_6256692_4 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000007379 119.0
HFD2_k127_6256692_5 Tfp pilus assembly protein FimV - - - 0.00003099 57.0
HFD2_k127_6256692_6 Fibronectin type III domain K12567 - 2.7.11.1 0.00006401 56.0
HFD2_k127_6260053_0 Tetratricopeptide repeat - - - 0.0000000000002807 85.0
HFD2_k127_6266000_0 PFAM ABC transporter transmembrane region - - - 5.882e-208 662.0
HFD2_k127_6266000_1 ADP-ribosylglycohydrolase - - - 0.00000000000000000000000001206 111.0
HFD2_k127_6266000_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000007712 106.0
HFD2_k127_626764_0 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000008748 199.0
HFD2_k127_626764_1 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000007896 161.0
HFD2_k127_626764_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000001001 130.0
HFD2_k127_626764_3 Protein conserved in bacteria - - - 0.0000000000001139 76.0
HFD2_k127_626764_4 PFAM sec-independent translocation protein mttA Hcf106 K03117 - - 0.00001655 49.0
HFD2_k127_6278662_0 mevalonate kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 338.0
HFD2_k127_6278662_1 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 319.0
HFD2_k127_6278662_2 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007733 254.0
HFD2_k127_6278662_3 - - - - 0.0000000000000000000000009709 110.0
HFD2_k127_6281746_0 PFAM type II secretion system protein E K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 481.0
HFD2_k127_6281746_1 - - - - 0.0000000000003335 81.0
HFD2_k127_6283311_0 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 351.0
HFD2_k127_6283311_1 N-terminal 7TM region of histidine kinase - - - 0.000000000000001517 79.0
HFD2_k127_6283311_2 cheY-homologous receiver domain - - - 0.0000000003503 66.0
HFD2_k127_6285983_0 - - - - 1.686e-315 985.0
HFD2_k127_6285983_1 carbohydrate transport K02027,K10117 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 451.0
HFD2_k127_6285983_10 PFAM deoxynucleoside kinase - - - 0.0000000000000003039 87.0
HFD2_k127_6285983_11 PFAM Peptidoglycan-binding lysin domain - - - 0.00000001336 67.0
HFD2_k127_6285983_12 Domain of unknown function DUF11 - - - 0.00000001669 68.0
HFD2_k127_6285983_2 Conserved hypothetical protein 698 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009816 430.0
HFD2_k127_6285983_3 glycerophosphodiester transmembrane transport K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 377.0
HFD2_k127_6285983_4 PFAM aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 335.0
HFD2_k127_6285983_5 PFAM binding-protein-dependent transport systems inner membrane component K02025,K10118,K17316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 334.0
HFD2_k127_6285983_6 purine nucleotide biosynthetic process K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002215 266.0
HFD2_k127_6285983_7 BtpA family K06971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008269 251.0
HFD2_k127_6285983_8 PFAM Forkhead-associated protein - - - 0.00000000000000000823 91.0
HFD2_k127_6285983_9 DNA N-6-adenine-methyltransferase (Dam) - - - 0.00000000000000009652 91.0
HFD2_k127_6295478_0 Glycosyl hydrolases family 2 K01190 - 3.2.1.23 7.036e-207 671.0
HFD2_k127_6295478_1 Cupin domain - - - 0.00000000000000396 81.0
HFD2_k127_6303564_0 response to antibiotic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001884 296.0
HFD2_k127_6303564_1 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001476 239.0
HFD2_k127_6303564_2 Endonuclease V - - - 0.00000000000000000002348 95.0
HFD2_k127_6303564_3 Bacterial SH3 domain - - - 0.0003366 53.0
HFD2_k127_6307922_0 Peptidase, M28 - - - 0.000000000000000000000000000000003624 145.0
HFD2_k127_6307922_1 ATP hydrolysis coupled proton transport - - - 0.0000000000000000000000000000001274 130.0
HFD2_k127_6307922_2 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000001677 85.0
HFD2_k127_6312211_0 G8 - - - 0.000000000000000000000000000000000000000000000000000000000006478 218.0
HFD2_k127_6312211_1 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000238 208.0
HFD2_k127_6315573_0 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 379.0
HFD2_k127_6315573_1 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000000000000000001647 232.0
HFD2_k127_6315573_2 Belongs to the peptidase S8 family - - - 0.0000000000000002644 89.0
HFD2_k127_6315573_3 Heat shock protein DnaJ domain protein - - - 0.0000003092 61.0
HFD2_k127_6315573_4 Glycosyl hydrolases family 25 - - - 0.0002232 52.0
HFD2_k127_6319578_0 melibiose metabolic process K01222,K07406 - 3.2.1.22,3.2.1.86 7.163e-205 646.0
HFD2_k127_6319578_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00822,K00833 - 2.6.1.18,2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 394.0
HFD2_k127_6319578_2 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000003378 225.0
HFD2_k127_6319578_3 transcriptional regulator - - - 0.000000000000000000000000000000004061 139.0
HFD2_k127_6319834_0 Protein of unknown function DUF89 - - - 0.0000000000000000000000000000000000000006793 162.0
HFD2_k127_6319834_1 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000005978 126.0
HFD2_k127_6319834_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000006527 76.0
HFD2_k127_6331432_0 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 610.0
HFD2_k127_6331432_1 Transcriptional regulator, Crp Fnr family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009434 301.0
HFD2_k127_6331432_2 - - - - 0.000000000000000000000000000000000000000000000000000000000001071 214.0
HFD2_k127_6331432_3 helix_turn _helix lactose operon repressor K02529 - - 0.0000000000000000000000000000000000000000000000000000007572 201.0
HFD2_k127_6331432_4 carbohydrate transport K02027 - - 0.000000000000000000000000000000000001285 143.0
HFD2_k127_6331432_5 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000002272 108.0
HFD2_k127_6331432_6 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K04088,K06897 - 2.5.1.105 0.0000000000001854 73.0
HFD2_k127_6331432_7 lacI family - - - 0.00000000001817 71.0
HFD2_k127_6331432_8 WD domain, G-beta repeat K12132 - 2.7.11.1 0.000006165 53.0
HFD2_k127_6331432_9 Two component transcriptional regulator, winged helix family K02483,K07660,K07667 - - 0.00005104 51.0
HFD2_k127_6334135_0 TIGRFAM diguanylate cyclase K02488 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.7.7.65 0.000000000021 77.0
HFD2_k127_6334998_0 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 429.0
HFD2_k127_6334998_1 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 414.0
HFD2_k127_6334998_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000008543 143.0
HFD2_k127_6335634_0 PFAM oxidoreductase domain protein - - - 6.061e-195 615.0
HFD2_k127_6335634_1 family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008141 609.0
HFD2_k127_6335634_10 transposase activity - - - 0.000000000000000000000000000000000000001505 154.0
HFD2_k127_6335634_11 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000001788 132.0
HFD2_k127_6335634_12 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000001541 125.0
HFD2_k127_6335634_13 COG3293 Transposase and inactivated derivatives - - - 0.0000000000000000000000001043 111.0
HFD2_k127_6335634_14 Protein of unknown function (DUF3341) - - - 0.000000000000000000003819 100.0
HFD2_k127_6335634_15 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000007198 104.0
HFD2_k127_6335634_16 PFAM Cytochrome C - - - 0.000000006159 67.0
HFD2_k127_6335634_17 ATPases associated with a variety of cellular activities K10112 - - 0.00000004304 55.0
HFD2_k127_6335634_18 lactoylglutathione lyase activity K05606 - 5.1.99.1 0.0001283 47.0
HFD2_k127_6335634_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004826 580.0
HFD2_k127_6335634_3 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 508.0
HFD2_k127_6335634_4 ATPases associated with a variety of cellular activities K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 451.0
HFD2_k127_6335634_5 myo-inosose-2 dehydratase activity K18910 - 5.1.3.30,5.1.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 355.0
HFD2_k127_6335634_6 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 327.0
HFD2_k127_6335634_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002129 282.0
HFD2_k127_6335634_8 PFAM transposase IS116 IS110 IS902 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005887 268.0
HFD2_k127_6335634_9 this gene contains a nucleotide ambiguity which may be the result of a sequencing error - - - 0.000000000000000000000000000000000000000000000000000000000000291 214.0
HFD2_k127_6335715_0 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 355.0
HFD2_k127_6335715_1 Aldo/keto reductase family K05882 - 1.1.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 315.0
HFD2_k127_6336731_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 484.0
HFD2_k127_6336731_1 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 419.0
HFD2_k127_6336731_10 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000002274 164.0
HFD2_k127_6336731_11 PFAM Archaeal ATPase - - - 0.000000000000000000000000000000000001127 163.0
HFD2_k127_6336731_12 - K06921 - - 0.00000000000000000007197 104.0
HFD2_k127_6336731_13 Two component regulator propeller - - - 0.0000000000000008559 94.0
HFD2_k127_6336731_14 Transcriptional regulatory protein, C terminal - - - 0.0000000005472 72.0
HFD2_k127_6336731_2 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 362.0
HFD2_k127_6336731_3 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 345.0
HFD2_k127_6336731_4 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 307.0
HFD2_k127_6336731_5 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001166 261.0
HFD2_k127_6336731_6 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000004752 200.0
HFD2_k127_6336731_7 Beta-galactosidase - - - 0.000000000000000000000000000000000000000000002769 184.0
HFD2_k127_6336731_8 Putative glycolipid-binding K09957 - - 0.00000000000000000000000000000000000000000006783 168.0
HFD2_k127_6336731_9 N-terminal TM domain of oligopeptide transport permease C K15582 - - 0.0000000000000000000000000000000000000000005382 164.0
HFD2_k127_6356503_0 PFAM NMT1 THI5 like domain protein K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 306.0
HFD2_k127_6356503_1 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009151 262.0
HFD2_k127_6356503_2 PFAM binding-protein-dependent transport systems inner membrane component K02050 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000001674 205.0
HFD2_k127_6356503_3 response to stress - - - 0.000000000000000000000000000000000000000000000000001089 196.0
HFD2_k127_6356503_4 phosphorelay signal transduction system K07658 - - 0.00000000000000000000621 99.0
HFD2_k127_6356503_5 - - - - 0.0007687 49.0
HFD2_k127_6364134_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01476,K01480 - 3.5.3.1,3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000003496 221.0
HFD2_k127_6364134_1 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000105 205.0
HFD2_k127_6364134_2 MacB-like periplasmic core domain - - - 0.00000000000002258 87.0
HFD2_k127_6364134_3 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000003305 66.0
HFD2_k127_6372495_0 Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 3.696e-221 714.0
HFD2_k127_6372495_1 3-isopropylmalate dehydrogenase activity K00030,K00052 - 1.1.1.41,1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 522.0
HFD2_k127_6372495_2 DNA methylase K00571,K13581 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008507 452.0
HFD2_k127_6372495_3 acetyltransferase K17840 - 2.3.1.59 0.0000000000004801 72.0
HFD2_k127_6377485_0 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 384.0
HFD2_k127_6377485_1 Belongs to the 5'-nucleotidase family K01081,K11751 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006213,GO:0006259,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007155,GO:0007159,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009164,GO:0009166,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019362,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0022610,GO:0031974,GO:0031981,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046135,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0051186,GO:0055086,GO:0070013,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0072524,GO:0072527,GO:0072529,GO:0090304,GO:0098609,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000006707 250.0
HFD2_k127_637895_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008147 584.0
HFD2_k127_637895_1 COGs COG3485 Protocatechuate 3 4-dioxygenase beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002098 248.0
HFD2_k127_637895_2 Dioxygenase K00449 - 1.13.11.3 0.000000000000001522 79.0
HFD2_k127_6380118_0 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 436.0
HFD2_k127_6380118_1 ATPase activity K02052,K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 435.0
HFD2_k127_6380118_2 PFAM binding-protein-dependent transport systems inner membrane component K02054,K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 339.0
HFD2_k127_6387612_0 diaminopimelate decarboxylase activity K01585,K01586 - 4.1.1.19,4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000002057 238.0
HFD2_k127_6387612_1 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000003198 183.0
HFD2_k127_6387612_2 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.0000000008599 68.0
HFD2_k127_6390501_0 Glycosyl hydrolases family 31 K01811 - 3.2.1.177 2.549e-238 754.0
HFD2_k127_6390501_1 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 381.0
HFD2_k127_6390501_2 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 336.0
HFD2_k127_6390501_3 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001608 273.0
HFD2_k127_6390501_4 helix_turn _helix lactose operon repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000001042 249.0
HFD2_k127_6390501_5 WD40 repeat-like protein - - - 0.000000000000000000000000000000003851 145.0
HFD2_k127_6390501_6 phosphoprotein phosphatase activity - - - 0.00000000000000000000000000000001172 131.0
HFD2_k127_6390501_7 response to heat K03668,K09914 - - 0.00000000000000000000003485 109.0
HFD2_k127_6390501_8 phosphoprotein phosphatase activity - - - 0.0000000000000000000005676 98.0
HFD2_k127_6390501_9 ECF sigma factor K03088 - - 0.000003205 51.0
HFD2_k127_6392144_0 WD domain, G-beta repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 564.0
HFD2_k127_6392144_1 WD-40 repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006977 503.0
HFD2_k127_6392144_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007552 246.0
HFD2_k127_6392144_3 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000146 215.0
HFD2_k127_6392144_4 Domain of unknown function (DUF3337) K15361 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030428,GO:0032182,GO:0032991,GO:0036211,GO:0043130,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051286,GO:0070647,GO:0071704,GO:1901564 - 0.000000000001042 83.0
HFD2_k127_6392144_5 trisaccharide binding - - - 0.00000000002136 79.0
HFD2_k127_6394662_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 576.0
HFD2_k127_6408107_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000001943 91.0
HFD2_k127_6408107_1 PFAM sigma-70 region 2 domain protein K03088 - - 0.0000003779 53.0
HFD2_k127_6408107_2 Polymer-forming cytoskeletal - - - 0.0003975 52.0
HFD2_k127_6421389_0 Psort location Cytoplasmic, score 8.87 K21417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 366.0
HFD2_k127_6421389_1 Phage integrase family - - - 0.00000000000000002524 94.0
HFD2_k127_6421971_0 Oxidoreductase family, C-terminal alpha beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 479.0
HFD2_k127_6421971_1 PFAM Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 393.0
HFD2_k127_6421971_10 Modulator K15837 GO:0000132,GO:0000226,GO:0000278,GO:0000922,GO:0001709,GO:0001965,GO:0003674,GO:0005092,GO:0005096,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005813,GO:0005815,GO:0005819,GO:0005829,GO:0005856,GO:0005938,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007052,GO:0007154,GO:0007163,GO:0007165,GO:0007186,GO:0007264,GO:0007265,GO:0007275,GO:0007346,GO:0007399,GO:0007400,GO:0007405,GO:0008022,GO:0008047,GO:0008104,GO:0008150,GO:0008283,GO:0008356,GO:0009987,GO:0010564,GO:0010638,GO:0014016,GO:0014017,GO:0015630,GO:0016020,GO:0016043,GO:0017145,GO:0019904,GO:0022008,GO:0022402,GO:0023052,GO:0030010,GO:0030154,GO:0030234,GO:0030695,GO:0031291,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032886,GO:0032991,GO:0033036,GO:0033043,GO:0035556,GO:0036445,GO:0040001,GO:0042802,GO:0043085,GO:0043087,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043547,GO:0043621,GO:0044087,GO:0044089,GO:0044093,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044464,GO:0044877,GO:0045165,GO:0045167,GO:0045175,GO:0045177,GO:0045179,GO:0045185,GO:0045787,GO:0048103,GO:0048518,GO:0048522,GO:0048699,GO:0048731,GO:0048856,GO:0048863,GO:0048865,GO:0048867,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050795,GO:0050896,GO:0051128,GO:0051130,GO:0051179,GO:0051234,GO:0051235,GO:0051293,GO:0051294,GO:0051301,GO:0051336,GO:0051345,GO:0051493,GO:0051495,GO:0051640,GO:0051641,GO:0051642,GO:0051649,GO:0051651,GO:0051653,GO:0051656,GO:0051657,GO:0051661,GO:0051716,GO:0051726,GO:0055057,GO:0055059,GO:0060236,GO:0060259,GO:0060341,GO:0060589,GO:0061351,GO:0061842,GO:0065007,GO:0065008,GO:0065009,GO:0070507,GO:0070840,GO:0071840,GO:0071944,GO:0072089,GO:0072686,GO:0090068,GO:0090169,GO:0090224,GO:0097431,GO:0097574,GO:0097575,GO:0098722,GO:0098772,GO:0099568,GO:0099738,GO:1902115,GO:1902117,GO:1902850,GO:1903047,GO:1903827,GO:1903829,GO:1904375,GO:1904377,GO:1904776,GO:1904778,GO:1905832 - 0.000000006366 69.0
HFD2_k127_6421971_11 peptidyl-tyrosine sulfation - - - 0.0000009273 62.0
HFD2_k127_6421971_12 Mechanosensitive ion channel K22044 GO:0003674,GO:0005215,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 - 0.000003124 57.0
HFD2_k127_6421971_2 XdhC Rossmann domain K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 304.0
HFD2_k127_6421971_3 TIR domain - - - 0.00000000000000000000000000000000000000000000000001002 193.0
HFD2_k127_6421971_4 PFAM RNA binding S1 domain protein - - - 0.0000000000000000000000000000000000000000000007243 175.0
HFD2_k127_6421971_5 ATPase AAA-2 domain protein K03696 - - 0.000000000000000000000000000000000000000005309 166.0
HFD2_k127_6421971_6 ATPase AAA-2 domain protein K03696 - - 0.000000000000000000000000000000000000009558 164.0
HFD2_k127_6421971_7 ROK family - - - 0.00000000000000000000000000000000000002402 159.0
HFD2_k127_6421971_8 Methyltransferase domain - - - 0.0000000000000000000000000005464 123.0
HFD2_k127_6421971_9 helix_turn _helix lactose operon repressor K02529 - - 0.0000000000000006703 89.0
HFD2_k127_6432231_0 Peptidoglycan-binding domain 1 protein - - - 0.0 1785.0
HFD2_k127_6432231_1 transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 566.0
HFD2_k127_6432231_10 PFAM CheW domain protein K03408 - - 0.00000000000000003058 89.0
HFD2_k127_6432231_11 COG0835 Chemotaxis signal transduction protein K03408 - - 0.00000000000001025 81.0
HFD2_k127_6432231_12 Chitinase class I K03791 - - 0.0001721 57.0
HFD2_k127_6432231_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 503.0
HFD2_k127_6432231_3 ATP-binding region, ATPase domain protein K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 424.0
HFD2_k127_6432231_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003997 286.0
HFD2_k127_6432231_5 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000007464 272.0
HFD2_k127_6432231_6 PFAM histidine kinase, HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002394 246.0
HFD2_k127_6432231_7 His Kinase A (phosphoacceptor) domain K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000001028 146.0
HFD2_k127_6432231_8 TIGRFAM YD repeat protein - - - 0.000000000000000001379 98.0
HFD2_k127_6432231_9 - - - - 0.000000000000000002282 93.0
HFD2_k127_6455758_0 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404,K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 503.0
HFD2_k127_6455758_1 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 380.0
HFD2_k127_6455758_2 Belongs to the peptidase S8 family - - - 0.0000000000009013 79.0
HFD2_k127_6458133_0 glycoside hydrolase family 2 sugar binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 567.0
HFD2_k127_6458133_1 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000833 334.0
HFD2_k127_6458133_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 294.0
HFD2_k127_6458133_4 FecR protein - - - 0.00000000000001901 83.0
HFD2_k127_6458133_5 coenzyme F420 binding - - - 0.0000002124 53.0
HFD2_k127_6458133_6 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00005287 50.0
HFD2_k127_6461019_0 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002891 270.0
HFD2_k127_6461019_1 - - - - 0.00000000000000000000000000000000000000000000001681 173.0
HFD2_k127_6461019_2 SCO1/SenC K03619,K07152 GO:0003674,GO:0005048,GO:0005488,GO:0033218,GO:0042277 - 0.0000000000000000000000000000000000000000000004097 176.0
HFD2_k127_6461019_3 - - - - 0.000000000000000002981 92.0
HFD2_k127_6461019_4 Cytochrome c K02305 - - 0.0000003416 60.0
HFD2_k127_6473828_0 Phosphoribulokinase / Uridine kinase family K00876 - 2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008973 433.0
HFD2_k127_6473828_1 enterobactin catabolic process K07214 - - 0.00000000000000000000000000000000000001404 156.0
HFD2_k127_6480917_0 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 550.0
HFD2_k127_6480917_1 response regulator, receiver K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 291.0
HFD2_k127_6480917_2 Histidine kinase K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000001582 203.0
HFD2_k127_6491952_0 Protein of unknown function (DUF2961) - - - 6.648e-210 657.0
HFD2_k127_6491952_1 Alpha-L-fucosidase K01190,K01205,K01206,K01224,K05349 - 3.2.1.21,3.2.1.23,3.2.1.50,3.2.1.51,3.2.1.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 358.0
HFD2_k127_6491952_2 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 334.0
HFD2_k127_6493225_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006238 265.0
HFD2_k127_6493225_1 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000005845 177.0
HFD2_k127_649435_0 ABC-type dipeptide transport system periplasmic component K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 512.0
HFD2_k127_649435_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004128 266.0
HFD2_k127_649435_2 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000003304 230.0
HFD2_k127_649435_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000003725 186.0
HFD2_k127_649435_4 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000001958 130.0
HFD2_k127_6504599_0 Di-haem oxidoreductase, putative peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 303.0
HFD2_k127_6504599_1 Hep Hag repeat protein - - - 0.0000000000000000000000000000000000000000000000002035 196.0
HFD2_k127_6504599_2 electron transfer activity - - - 0.00000000003635 64.0
HFD2_k127_6504928_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.226e-267 848.0
HFD2_k127_6504928_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein - - - 5.186e-235 743.0
HFD2_k127_6504928_2 ATP synthesis coupled electron transport K00342,K00343,K05568 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 490.0
HFD2_k127_6504928_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K14088 - - 0.000000000000000000000000000000000000000000000000000000000000000003311 228.0
HFD2_k127_6504928_4 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000001655 125.0
HFD2_k127_6504928_5 Multisubunit Na H antiporter MnhC subunit K00340,K05567 - 1.6.5.3 0.0000000000000000000000004881 108.0
HFD2_k127_6506622_0 NADPH:quinone reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 397.0
HFD2_k127_6506622_1 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 341.0
HFD2_k127_6506622_10 Cupin domain - - - 0.000000000000000000000000000000000000000007773 162.0
HFD2_k127_6506622_11 PFAM Rhodanese domain protein - - - 0.00000000000000000000000000000000001649 142.0
HFD2_k127_6506622_12 YjbR - - - 0.0000000000000000000000000000000003493 138.0
HFD2_k127_6506622_13 nitrogen fixation - - - 0.000000000000000000000000000008882 124.0
HFD2_k127_6506622_14 transposition K07497 - - 0.0000000000000000000000004881 108.0
HFD2_k127_6506622_15 - - - - 0.000000000000000000000005419 107.0
HFD2_k127_6506622_16 activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation - - - 0.00000000005215 77.0
HFD2_k127_6506622_17 - - - - 0.00000000006939 69.0
HFD2_k127_6506622_2 transposition K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003922 288.0
HFD2_k127_6506622_3 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009105 271.0
HFD2_k127_6506622_4 NADPH:quinone reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003316 266.0
HFD2_k127_6506622_5 PFAM Vitamin K epoxide reductase - - - 0.000000000000000000000000000000000000000000000000000000000000008821 232.0
HFD2_k127_6506622_6 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000003426 205.0
HFD2_k127_6506622_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000008768 206.0
HFD2_k127_6506622_8 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000000000000000003513 188.0
HFD2_k127_6506622_9 cellulose binding - - - 0.000000000000000000000000000000000000000000002439 178.0
HFD2_k127_6513375_0 Nacht domain K13730 - - 0.000000000000000000000000000000000000000000000000000000000003211 236.0
HFD2_k127_6513375_1 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.00000000000000000000000000001152 127.0
HFD2_k127_6514308_0 PFAM glycoside hydrolase, family 1 K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 419.0
HFD2_k127_6514308_1 RelA SpoT domain protein - - - 0.00000000000000000000000000000000000000000000000000000000002707 219.0
HFD2_k127_6514308_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000009419 204.0
HFD2_k127_6514308_3 N-Acetylmuramoyl-L-alanine amidase - - - 0.0000000000000000000001754 107.0
HFD2_k127_6514308_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000501 102.0
HFD2_k127_6514308_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000002413 89.0
HFD2_k127_6515510_0 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008997 312.0
HFD2_k127_6515510_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000008983 234.0
HFD2_k127_6515510_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000005294 108.0
HFD2_k127_6515510_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031668,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.0000000000000001216 89.0
HFD2_k127_6515510_4 Diphthamide synthase - - - 0.0000000000000006218 78.0
HFD2_k127_6515510_5 Cysteine-rich secretory protein family - - - 0.0000000000001836 80.0
HFD2_k127_6515679_0 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 310.0
HFD2_k127_6515679_1 Bacterial extracellular solute-binding protein K02027,K10117 - - 0.000000000000000000000000000000000000000000003853 170.0
HFD2_k127_6544517_0 Belongs to the glycosyl hydrolase 13 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005778 518.0
HFD2_k127_6544517_1 PFAM Binding-protein-dependent transport system inner membrane component K15772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006461 321.0
HFD2_k127_6544517_2 PFAM Binding-protein-dependent transport system inner membrane component K02025,K15771 - - 0.0000000000000000000000000000000000000000000000000000000002662 226.0
HFD2_k127_6551295_0 ANTAR K22010 - - 0.000000000000000002895 91.0
HFD2_k127_6551295_1 DUF218 domain - - - 0.0000000000000004129 87.0
HFD2_k127_6551295_2 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 0.00000000000004104 72.0
HFD2_k127_6551295_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0005693 43.0
HFD2_k127_655313_0 Iron-containing alcohol dehydrogenase K00096 - 1.1.1.261 0.00000000000000000000000000000000000000000000000000000003999 210.0
HFD2_k127_655313_1 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K04517 - 1.3.1.12 0.0000000000000001197 83.0
HFD2_k127_6553235_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.303e-214 689.0
HFD2_k127_6553235_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 323.0
HFD2_k127_6553235_2 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000000006401 246.0
HFD2_k127_6553235_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000001326 227.0
HFD2_k127_6553235_4 Two component transcriptional regulator, winged helix family - - - 0.000000000000000000000000000000000000000000000000000000001794 213.0
HFD2_k127_6554013_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00112 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000003336 236.0
HFD2_k127_6554013_1 BFD domain protein 2Fe-2S -binding domain protein K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000006472 209.0
HFD2_k127_6554013_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00113 - 1.1.5.3 0.000000000000000000001083 96.0
HFD2_k127_6554283_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000002549 252.0
HFD2_k127_6554283_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000001513 247.0
HFD2_k127_6554283_2 Fibronectin-binding A domain protein - - - 0.000000000000000000000000000000001814 134.0
HFD2_k127_6554283_3 PFAM Formylglycine-generating sulfatase enzyme K20333 - - 0.00000000000000002773 94.0
HFD2_k127_6554283_4 Tetratricopeptide repeat - - - 0.0000000000000003858 90.0
HFD2_k127_6557459_0 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0 1463.0
HFD2_k127_655755_0 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441,K10545,K10548 - 3.6.3.17 5.513e-250 781.0
HFD2_k127_655755_1 tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 516.0
HFD2_k127_655755_2 Belongs to the binding-protein-dependent transport system permease family K10544,K10547 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 450.0
HFD2_k127_655755_3 DinB family - - - 0.00000000000000000000000000000000000000000000000000000002701 202.0
HFD2_k127_655755_4 Peptidase family S41 - - - 0.000000000000000000000000000000000000000000000000000001014 203.0
HFD2_k127_655755_5 asparaginyl-tRNA synthetase K01893 - 6.1.1.22 0.000000000000000000002876 93.0
HFD2_k127_655755_6 Periplasmic binding protein domain K10543,K10546 - - 0.000000000001478 69.0
HFD2_k127_655755_7 Transglycosylase associated protein - - - 0.0000000958 58.0
HFD2_k127_655755_8 FR47-like protein - - - 0.00001059 56.0
HFD2_k127_6566931_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000156 247.0
HFD2_k127_6566931_1 blue (type 1) copper K00368 - 1.7.2.1 0.0000000000000000209 96.0
HFD2_k127_6566931_2 PFAM blue (type 1) copper domain protein K00368,K02638,K05772 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1 0.000000000001187 81.0
HFD2_k127_6566931_3 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.00000000002145 78.0
HFD2_k127_6566931_4 Copper binding proteins, plastocyanin/azurin family - - - 0.00000002845 67.0
HFD2_k127_657022_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.537e-211 681.0
HFD2_k127_657022_1 DNA helicase - - - 0.0000000000000000000000000000000000000000000000000000000000000006507 227.0
HFD2_k127_657022_2 EamA-like transporter family - - - 0.0000000000000000000000000001813 126.0
HFD2_k127_657022_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000001093 61.0
HFD2_k127_6574214_0 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006978 405.0
HFD2_k127_6574214_1 PFAM MerR family regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 372.0
HFD2_k127_6574214_2 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008647 350.0
HFD2_k127_6574214_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000248 269.0
HFD2_k127_6574214_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006569 266.0
HFD2_k127_6574214_5 PFAM Bacterial regulatory proteins, lacI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008573 257.0
HFD2_k127_6574214_6 - K13652 - - 0.000000000000000000000000000000000000000000000000000021 195.0
HFD2_k127_6574214_7 YCII-related domain - - - 0.000000000000000000000000000000001884 132.0
HFD2_k127_6574214_8 methyltransferase activity - - - 0.000000005257 60.0
HFD2_k127_6575106_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 598.0
HFD2_k127_6575106_1 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 490.0
HFD2_k127_6575106_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 471.0
HFD2_k127_6575106_3 Periplasmic binding protein domain K02058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 432.0
HFD2_k127_6575106_4 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 383.0
HFD2_k127_6575106_5 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 331.0
HFD2_k127_657649_0 glycerophosphodiester transmembrane transport K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 351.0
HFD2_k127_657649_1 transmembrane transport K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17242,K17316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000636 283.0
HFD2_k127_657649_2 PFAM extracellular solute-binding protein family 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006353 269.0
HFD2_k127_6580816_0 Alpha mannosidase, middle domain K01191,K15524,K16869 GO:0003674,GO:0003824,GO:0004553,GO:0004559,GO:0005975,GO:0005996,GO:0006013,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015923,GO:0016787,GO:0016798,GO:0019318,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0071704,GO:1901135,GO:1901564 2.3.1.204,3.2.1.170,3.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 580.0
HFD2_k127_6580816_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 536.0
HFD2_k127_6580816_2 helix_turn _helix lactose operon repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 312.0
HFD2_k127_6580816_3 PFAM binding-protein-dependent transport systems inner membrane component K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17316 - - 0.0000000000000000000000000000000000000000000000009273 180.0
HFD2_k127_6580816_4 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000000000000000000000001348 192.0
HFD2_k127_6580816_5 Bacterial extracellular solute-binding protein K02027,K10120 - - 0.000000000000000000000000000000000000000000000006748 190.0
HFD2_k127_6580816_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000004944 158.0
HFD2_k127_6580816_7 - - - - 0.00000000005509 71.0
HFD2_k127_6584756_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007426 478.0
HFD2_k127_6584756_1 TIGRFAM conserved K09935 - - 0.000000000000000000000000000000000000000000000000000000000000000000002939 237.0
HFD2_k127_6584756_2 MBOAT, membrane-bound O-acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000001317 202.0
HFD2_k127_6584756_3 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000005921 101.0
HFD2_k127_6584756_4 PFAM PIN domain - - - 0.000000000009969 71.0
HFD2_k127_6584756_5 - - - - 0.0000008837 62.0
HFD2_k127_6584756_6 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.0007621 52.0
HFD2_k127_6584963_0 Domain of unknown function (DUF4872) - - - 0.0000000000000000000000000000000000000000002027 172.0
HFD2_k127_6584963_1 transcription factor binding K07315,K17763 - 3.1.3.3 0.0000000000000000000000000000004054 141.0
HFD2_k127_6590751_0 Thermophilic metalloprotease (M29) K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 374.0
HFD2_k127_6590751_1 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000001387 196.0
HFD2_k127_6590751_2 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.000000000000000000000000000000000008651 144.0
HFD2_k127_6590751_3 subunit of a heme lyase K02200 - - 0.000000000000000000004677 99.0
HFD2_k127_6600094_0 Baseplate J-like protein - - - 5.964e-269 855.0
HFD2_k127_6600094_1 Phage late control gene D protein (GPD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 514.0
HFD2_k127_6600094_10 - - - - 0.00000000000000000000008042 102.0
HFD2_k127_6600094_11 Major Facilitator Superfamily - - - 0.00000000000000000001076 105.0
HFD2_k127_6600094_12 - - - - 0.00000000000000005028 90.0
HFD2_k127_6600094_13 amine dehydrogenase activity - - - 0.00000000000000007033 94.0
HFD2_k127_6600094_14 - - - - 0.000000000002393 77.0
HFD2_k127_6600094_15 - - - - 0.0000000000778 72.0
HFD2_k127_6600094_2 Phage tail sheath protein K06907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 506.0
HFD2_k127_6600094_3 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000008575 218.0
HFD2_k127_6600094_4 - - - - 0.0000000000000000000000000000000000000000000000000000000002183 211.0
HFD2_k127_6600094_5 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000000000000000000027 194.0
HFD2_k127_6600094_6 Phage tail protein (Tail_P2_I) - - - 0.0000000000000000000000000000000000000000006324 162.0
HFD2_k127_6600094_7 - K06903 - - 0.00000000000000000000000000000000000000006407 156.0
HFD2_k127_6600094_8 Bacterial-like globin K06886 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000001653 150.0
HFD2_k127_6600094_9 - - - - 0.00000000000000000000000000000000001252 138.0
HFD2_k127_6605345_0 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 512.0
HFD2_k127_6605345_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 291.0
HFD2_k127_6605345_2 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000001301 159.0
HFD2_k127_6605345_3 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000002412 96.0
HFD2_k127_6605345_4 Baseplate J-like protein K01218 - 3.2.1.78 0.0000000000000000001511 97.0
HFD2_k127_6607862_0 PFAM Cytochrome C assembly protein K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 480.0
HFD2_k127_6607862_1 PFAM ABC transporter related K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000001174 238.0
HFD2_k127_6607862_2 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.000000000000000000000000000000000000002141 154.0
HFD2_k127_6607862_3 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000001764 135.0
HFD2_k127_6607862_4 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.00000000000000000000001151 104.0
HFD2_k127_6607862_5 subunit of a heme lyase K02200 - - 0.000000000000000000009408 100.0
HFD2_k127_6607862_6 Cytochrome c - - - 0.0000000000183 76.0
HFD2_k127_6611023_0 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000000000000000000000000000000000002417 190.0
HFD2_k127_6611023_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07710 - 2.7.13.3 0.000000000000000000000000000001375 123.0
HFD2_k127_6611023_3 helix_turn_helix, arabinose operon control protein K07720 - - 0.000000000000003241 81.0
HFD2_k127_6612146_0 Belongs to the peptidase S8 family - - - 0.000000000000001717 86.0
HFD2_k127_6612146_1 Domain of unknown function (DUF4397) - - - 0.0000000005894 70.0
HFD2_k127_6612146_2 WD40-like Beta Propeller Repeat K03641 - - 0.0003485 46.0
HFD2_k127_6616793_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 0.0 1162.0
HFD2_k127_6616793_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000006151 196.0
HFD2_k127_6616793_2 transposition K07497 - - 0.00000000000000000000000000000002231 130.0
HFD2_k127_6616793_3 transposition K07497 - - 0.00000000002129 67.0
HFD2_k127_6616793_4 - - - - 0.000005036 56.0
HFD2_k127_662888_0 ABC transporter K02056,K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 587.0
HFD2_k127_662888_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 496.0
HFD2_k127_662888_2 ABC-type sugar transport system periplasmic component K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 436.0
HFD2_k127_662888_3 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000001114 217.0
HFD2_k127_6634505_0 methyltransferase K15471 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016741,GO:0022607,GO:0032259,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071770,GO:0071840,GO:0071944 - 0.000000000000000000000000000000000000000000001211 174.0
HFD2_k127_6634505_1 O-Antigen ligase - - - 0.00000000000002349 87.0
HFD2_k127_6641245_0 phosphohistidine phosphatase, SixA - - - 0.0000000000000000000008859 99.0
HFD2_k127_6641245_1 - - - - 0.000000000000000006597 91.0
HFD2_k127_6641245_2 PFAM NB-ARC domain K16247 - - 0.0004367 49.0
HFD2_k127_664127_0 intracellular signal transduction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 554.0
HFD2_k127_664127_1 Glycosyl hydrolase family 53 K01224 - 3.2.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000888 270.0
HFD2_k127_6667879_0 Periplasmic binding protein domain K02058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 346.0
HFD2_k127_6667879_1 PFAM Xylose isomerase domain protein TIM barrel K06606 - 5.3.99.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 322.0
HFD2_k127_6667879_2 Major Facilitator Superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008413 288.0
HFD2_k127_6667879_3 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000002178 239.0
HFD2_k127_6667879_4 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000829 146.0
HFD2_k127_6667879_5 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000003131 147.0
HFD2_k127_6667879_6 Transposase IS66 family K07484 - - 0.0000005113 57.0
HFD2_k127_6667879_7 PFAM transposase, IS4 family protein - - - 0.000002823 52.0
HFD2_k127_6672413_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 533.0
HFD2_k127_6672413_1 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000002709 213.0
HFD2_k127_6672413_2 PFAM von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000001219 159.0
HFD2_k127_6672413_3 Bacterial extracellular solute-binding protein - - - 0.0000000000001846 80.0
HFD2_k127_6672413_4 Ceramidase - - - 0.0000003392 62.0
HFD2_k127_6672413_5 MFS transporter - - - 0.0003054 47.0
HFD2_k127_6684942_0 Domain of unknown function (DUF4432) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002599 258.0
HFD2_k127_6684942_1 mandelate racemase muconate lactonizing K01706 - 4.2.1.40 0.000000000000000000000000000000000000000000000000003232 183.0
HFD2_k127_6684942_2 mannose metabolic process K01191 - 3.2.1.24 0.00000000000000005839 87.0
HFD2_k127_6695491_0 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000001026 191.0
HFD2_k127_6695491_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000001759 98.0
HFD2_k127_670816_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 383.0
HFD2_k127_670816_1 serine threonine protein kinase K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.00000000000000000000000000000000001141 143.0
HFD2_k127_6719239_0 Belongs to the glycosyl hydrolase 13 family - - - 0.0 1904.0
HFD2_k127_6719239_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.0000000000000000000000000000000000000000009087 158.0
HFD2_k127_6719239_2 - - - - 0.000000000006789 70.0
HFD2_k127_672709_0 PFAM histidine kinase, HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007118 355.0
HFD2_k127_672709_1 Periplasmic binding protein domain - - - 0.000000000000000000000000000000000000000000001714 181.0
HFD2_k127_6728985_0 PFAM regulatory protein LuxR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 402.0
HFD2_k127_6728985_1 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000005511 191.0
HFD2_k127_6736554_0 PFAM Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 526.0
HFD2_k127_674220_0 TIGRFAM carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 471.0
HFD2_k127_674220_1 Vault protein inter-alpha-trypsin domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 323.0
HFD2_k127_674220_2 Carbamoyl-phosphate synthetase large chain domain protein K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000001365 166.0
HFD2_k127_674220_3 - - - - 0.00000000000000000000000000000000000000000004864 172.0
HFD2_k127_674220_4 PFAM transposase, IS4 family protein - - - 0.000000000000000000000144 110.0
HFD2_k127_674220_5 peptidase C60 sortase A and B K07284 - 3.4.22.70 0.0000000002227 70.0
HFD2_k127_674220_6 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.000000005415 68.0
HFD2_k127_6743011_0 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001143 283.0
HFD2_k127_6743011_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001131 244.0
HFD2_k127_6743011_2 Rab subfamily of small GTPases K07876 GO:0000166,GO:0000278,GO:0000281,GO:0000910,GO:0001882,GO:0001883,GO:0002376,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005543,GO:0005546,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005769,GO:0005829,GO:0005886,GO:0005905,GO:0006810,GO:0006887,GO:0007049,GO:0007154,GO:0007165,GO:0007264,GO:0007265,GO:0007275,GO:0007399,GO:0008021,GO:0008104,GO:0008150,GO:0008289,GO:0009719,GO:0009987,GO:0010008,GO:0010033,GO:0012505,GO:0012506,GO:0016020,GO:0016043,GO:0016192,GO:0016197,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019882,GO:0019904,GO:0022008,GO:0022402,GO:0023052,GO:0030030,GO:0030133,GO:0030135,GO:0030136,GO:0030139,GO:0030154,GO:0030182,GO:0030658,GO:0030659,GO:0030662,GO:0030665,GO:0030672,GO:0031090,GO:0031175,GO:0031224,GO:0031225,GO:0031253,GO:0031300,GO:0031410,GO:0031982,GO:0032456,GO:0032482,GO:0032501,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0032940,GO:0033036,GO:0033365,GO:0034613,GO:0035091,GO:0035556,GO:0035639,GO:0036010,GO:0036094,GO:0042221,GO:0042995,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0044085,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044440,GO:0044444,GO:0044446,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0045171,GO:0045202,GO:0045334,GO:0046903,GO:0046907,GO:0048227,GO:0048468,GO:0048666,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051301,GO:0051641,GO:0051649,GO:0051716,GO:0055037,GO:0055038,GO:0061640,GO:0065007,GO:0070382,GO:0070727,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071495,GO:0071532,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:0097458,GO:0097708,GO:0097734,GO:0098563,GO:0098588,GO:0098590,GO:0098793,GO:0098805,GO:0098993,GO:0099501,GO:0099503,GO:0120025,GO:0120036,GO:0120038,GO:0140112,GO:1901265,GO:1901363,GO:1901981,GO:1902936,GO:1903047,GO:1990089,GO:1990090,GO:1990182 - 0.000000000000000000000000000000000001016 145.0
HFD2_k127_6743011_3 SnoaL-like polyketide cyclase - - - 0.000005631 55.0
HFD2_k127_6743255_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 320.0
HFD2_k127_6743255_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 301.0
HFD2_k127_6743255_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000000000000000000000006517 213.0
HFD2_k127_6743255_3 Aminoacyl-tRNA editing domain - - - 0.00000000000000000000000000000000000000000000000000000001057 201.0
HFD2_k127_6743255_4 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000742 203.0
HFD2_k127_6743255_5 PFAM regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000000000002209 185.0
HFD2_k127_6743255_6 Rossmann-like domain - - - 0.000000000000000000000000000000000000000000008727 176.0
HFD2_k127_6743255_7 Beta-galactosidase - - - 0.00000000000009133 83.0
HFD2_k127_6743255_8 2TM domain - - - 0.000005504 54.0
HFD2_k127_6743255_9 - - - - 0.0003164 47.0
HFD2_k127_6749314_0 PFAM binding-protein-dependent transport systems inner membrane component K15581 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 297.0
HFD2_k127_6749314_1 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006883 281.0
HFD2_k127_6749314_2 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006857,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0015833,GO:0030288,GO:0030313,GO:0031975,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750 - 0.00000000000000000000000000000000000000000000000000000000000000001233 245.0
HFD2_k127_6749314_3 Peptidase S9, prolyl oligopeptidase active site domain protein - - - 0.00000000000000000000000000007355 124.0
HFD2_k127_6755591_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 479.0
HFD2_k127_6755591_1 PFAM periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000003804 228.0
HFD2_k127_6755591_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000002812 191.0
HFD2_k127_6755591_3 - - - - 0.0003975 53.0
HFD2_k127_6761275_0 AAA ATPase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 403.0
HFD2_k127_6761275_1 Transposase is116 is110 is902 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001762 247.0
HFD2_k127_6761275_2 AAA domain - - - 0.000000000000000000000000000000000000000000000000003399 188.0
HFD2_k127_6761275_3 NACHT domain - - - 0.00000000000000000000000000000000002652 149.0
HFD2_k127_6761275_4 Platelet-activating factor acetylhydrolase, isoform II - - - 0.0000000000000000000000000002094 128.0
HFD2_k127_6761275_5 Carbon-nitrogen hydrolase - - - 0.0000000165 59.0
HFD2_k127_6761275_6 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00003926 48.0
HFD2_k127_6761766_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 577.0
HFD2_k127_6761766_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 407.0
HFD2_k127_6761766_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000001809 271.0
HFD2_k127_6761766_3 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000001762 233.0
HFD2_k127_6761766_4 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000006757 202.0
HFD2_k127_6761766_5 self proteolysis - - - 0.000000000000000000000000000000000005094 148.0
HFD2_k127_6765943_0 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 318.0
HFD2_k127_6765943_1 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 301.0
HFD2_k127_6765943_2 COG2133 Glucose sorbosone dehydrogenases - - - 0.000000000000000000000000000000000002444 141.0
HFD2_k127_6765943_3 pfkB family carbohydrate kinase - - - 0.000000000000000000000000001985 119.0
HFD2_k127_6765943_4 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000005345 109.0
HFD2_k127_6765943_5 Wd40 repeat-containing protein - - - 0.00000000000005094 86.0
HFD2_k127_6765943_6 COG3103 SH3 domain protein K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.00005921 54.0
HFD2_k127_6765943_7 sh3 domain protein K01448,K04771 - 3.4.21.107,3.5.1.28 0.00007584 55.0
HFD2_k127_6765943_8 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - 0.000287 53.0
HFD2_k127_6776130_0 PFAM Stage V sporulation protein S K06416 - - 0.000000000000000000000002727 105.0
HFD2_k127_6776130_1 TerB N-terminal domain - - - 0.000000000000000002779 99.0
HFD2_k127_6776130_2 Response regulator receiver domain K03413 - - 0.0000000000000000676 88.0
HFD2_k127_6778961_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 417.0
HFD2_k127_6778961_1 Peptidase family S58 - - - 0.00000000000000000000000000000000000000000000000000000001244 203.0
HFD2_k127_6782479_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000000000000000000000000000443 139.0
HFD2_k127_6782479_1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07669,K07672 - - 0.0000000000000000000000000002838 117.0
HFD2_k127_6782479_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000008812 59.0
HFD2_k127_6782479_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00005647 50.0
HFD2_k127_6782590_0 NB-ARC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 398.0
HFD2_k127_6782590_1 Transcriptional regulatory protein, C terminal K07668,K07775 - - 0.00000000000000000000000000000000000000000000000000000000000000164 227.0
HFD2_k127_6782590_2 histidine kinase HAMP region domain protein K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000001302 196.0
HFD2_k127_6782590_3 cellular response to heat K09807 - - 0.000000000000000000000000001864 125.0
HFD2_k127_6782963_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001718 298.0
HFD2_k127_6782963_1 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000004549 206.0
HFD2_k127_6782963_2 domain, Protein - - - 0.0000000000000000000000000000000000000000000000001124 205.0
HFD2_k127_6782963_3 histidine kinase A domain protein - - - 0.000000000000000000000000000008718 139.0
HFD2_k127_6782963_4 Histidine kinase - - - 0.0000000000000005045 94.0
HFD2_k127_6782963_5 cellulase activity - - - 0.0000005532 64.0
HFD2_k127_6788681_0 PFAM amino acid permease-associated region K20265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 542.0
HFD2_k127_6788681_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000003408 152.0
HFD2_k127_6788681_2 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000003802 106.0
HFD2_k127_6790301_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756,K01857 - 4.3.2.2,5.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 556.0
HFD2_k127_6790301_1 SMART PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002589 255.0
HFD2_k127_6796022_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000001974 240.0
HFD2_k127_6804687_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829,K19969,K21342 - 2.7.1.71,4.2.3.152,4.2.3.154,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 584.0
HFD2_k127_6804687_1 Alpha beta hydrolase - - - 0.0001147 45.0
HFD2_k127_6805872_0 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000008748 231.0
HFD2_k127_6810579_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.302e-281 878.0
HFD2_k127_6810579_1 - - - - 0.00000000000000000000000000002696 120.0
HFD2_k127_6810579_2 Polysaccharide deacetylase - - - 0.00000004982 63.0
HFD2_k127_6819399_0 Abhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 305.0
HFD2_k127_6819399_1 sh3 domain protein K07282 - - 0.0000000000000000000000000000000000000000000000000000001308 209.0
HFD2_k127_6819399_2 5'-nucleotidase K01081,K01119 - 3.1.3.5,3.1.3.6,3.1.4.16 0.000001808 60.0
HFD2_k127_6839678_0 Glycosyl hydrolase family 9 - - - 7.746e-204 648.0
HFD2_k127_6839678_1 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 357.0
HFD2_k127_6839678_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000455 235.0
HFD2_k127_6839678_3 SMART PDZ DHR GLGF domain protein K11749 - - 0.00000000000000000000000000000000000000000000000000000000000006614 231.0
HFD2_k127_6839678_4 PFAM Phosphatidic acid phosphatase type 2 haloperoxidase K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000007884 181.0
HFD2_k127_6839678_5 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000000000000000009429 173.0
HFD2_k127_6839678_6 VKc - - - 0.0000000000000006731 84.0
HFD2_k127_6843934_0 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 389.0
HFD2_k127_6843934_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000001405 68.0
HFD2_k127_684987_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 287.0
HFD2_k127_684987_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000001774 231.0
HFD2_k127_684987_2 - - - - 0.0000000000000000000000000000000000006719 145.0
HFD2_k127_684987_3 serine threonine protein kinase K14949 GO:0001898,GO:0001899,GO:0002682,GO:0002684,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006468,GO:0006520,GO:0006536,GO:0006538,GO:0006541,GO:0006543,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0019752,GO:0030100,GO:0031341,GO:0031342,GO:0031347,GO:0031349,GO:0032879,GO:0035821,GO:0036211,GO:0040007,GO:0042268,GO:0042802,GO:0043170,GO:0043207,GO:0043412,GO:0043436,GO:0043648,GO:0043649,GO:0043900,GO:0043901,GO:0043903,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044403,GO:0044413,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044501,GO:0045918,GO:0046395,GO:0046777,GO:0048518,GO:0048519,GO:0048523,GO:0048583,GO:0048584,GO:0050764,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0051709,GO:0051710,GO:0051711,GO:0051713,GO:0051802,GO:0051803,GO:0051817,GO:0051832,GO:0052027,GO:0052031,GO:0052164,GO:0052173,GO:0052190,GO:0052200,GO:0052231,GO:0052250,GO:0052255,GO:0052303,GO:0052348,GO:0052369,GO:0052509,GO:0052510,GO:0052550,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052567,GO:0052572,GO:0060627,GO:0065007,GO:0071704,GO:0071944,GO:0075136,GO:0080134,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.11.1 0.000000000000000000000000000000001137 150.0
HFD2_k127_684987_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000008135 115.0
HFD2_k127_684987_5 von Willebrand factor type A domain - - - 0.00000000000000000005058 102.0
HFD2_k127_684987_6 FHA domain K07315 - 3.1.3.3 0.000000009692 64.0
HFD2_k127_685799_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 559.0
HFD2_k127_685799_1 FtsX-like permease family K02004 - - 0.00000001788 62.0
HFD2_k127_685799_2 cheY-homologous receiver domain K02490 - - 0.0004856 53.0
HFD2_k127_6869541_0 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 348.0
HFD2_k127_6869541_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 306.0
HFD2_k127_6869541_2 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000004253 145.0
HFD2_k127_6869541_3 translation initiation inhibitor, yjgF family K04782 - 4.2.99.21 0.000000000000000000000000000000000003666 143.0
HFD2_k127_6870432_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 9.965e-255 805.0
HFD2_k127_6870432_1 diacylglycerol kinase, catalytic - - - 0.000000000000000000000000000000000000000000000000000000000003926 220.0
HFD2_k127_6870432_2 Cation transport regulator - - - 0.00000000000000000000000000000000000003372 155.0
HFD2_k127_6870432_3 - - - - 0.0000000000000000000000000002532 127.0
HFD2_k127_6870432_4 Belongs to the Nudix hydrolase family K01515,K03574 - 3.6.1.13,3.6.1.55 0.00000000001101 72.0
HFD2_k127_6870432_5 Bacterial membrane protein, YfhO - - - 0.00000000004054 76.0
HFD2_k127_687051_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 451.0
HFD2_k127_687051_1 COGs COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000009488 240.0
HFD2_k127_687051_2 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000001284 183.0
HFD2_k127_687051_3 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000009221 162.0
HFD2_k127_687051_4 similarity to GB CAD86359.1 - - - 0.000000000000000000000000000000000508 134.0
HFD2_k127_687051_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000005179 67.0
HFD2_k127_6870852_0 Ribulose-phosphate 3 epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000004662 250.0
HFD2_k127_6870852_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000009467 246.0
HFD2_k127_6870852_2 protein homooligomerization - - - 0.000000000000000000000000000000000000000000000000000000000001976 216.0
HFD2_k127_6870852_3 domain, Protein - - - 0.000000000000000000000000000005357 139.0
HFD2_k127_6870852_4 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000002212 114.0
HFD2_k127_6870852_5 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000006493 106.0
HFD2_k127_6870852_6 HNH endonuclease - - - 0.00000000000000000004086 93.0
HFD2_k127_6870852_7 Ribosomal L28 family K02902 - - 0.000000000002538 68.0
HFD2_k127_6874917_0 transport system K01992 - - 2.807e-199 646.0
HFD2_k127_6874917_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 361.0
HFD2_k127_6874917_2 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003095 283.0
HFD2_k127_6874917_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000002446 177.0
HFD2_k127_6874917_4 - K01992 - - 0.0000000000000000000000000008806 121.0
HFD2_k127_6877377_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 619.0
HFD2_k127_6877377_1 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008124 497.0
HFD2_k127_6877377_2 periplasmic binding protein LacI transcriptional regulator K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000002804 242.0
HFD2_k127_6877377_3 -acetyltransferase - - - 0.000000000000000000000000000000000000000001103 168.0
HFD2_k127_6877377_4 Major facilitator superfamily - - - 0.00000000000000000004609 103.0
HFD2_k127_6881932_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 451.0
HFD2_k127_6881932_1 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 364.0
HFD2_k127_6881932_2 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000003147 188.0
HFD2_k127_6881932_3 CoA binding domain - - - 0.00000000000000000000000000000000000000000003231 165.0
HFD2_k127_6881932_4 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.0000000000000000000000000000000000000005849 160.0
HFD2_k127_6881932_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000004773 57.0
HFD2_k127_6886148_0 GMC oxidoreductase - - - 4.515e-250 779.0
HFD2_k127_6886148_1 ABC-type Fe3 transport system permease component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 572.0
HFD2_k127_6886148_2 Binding-protein-dependent transport system inner membrane component K17316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 430.0
HFD2_k127_6886148_3 glycerophosphodiester transmembrane transport K02026,K17317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 412.0
HFD2_k127_6886148_4 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 385.0
HFD2_k127_6886148_5 the ABC transporter K02010,K02052 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 379.0
HFD2_k127_6886148_6 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 334.0
HFD2_k127_6886148_7 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 311.0
HFD2_k127_6886148_8 PFAM extracellular solute-binding protein family 1 K10117,K17315 - - 0.000000000000000000000000000000000000000000000000000000000006721 209.0
HFD2_k127_6886148_9 FecR protein - - - 0.00000000000496 77.0
HFD2_k127_688822_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 317.0
HFD2_k127_688822_1 histone H2A K63-linked ubiquitination K01205,K07004,K12132 - 2.7.11.1,3.2.1.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000003155 284.0
HFD2_k127_688822_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000002803 154.0
HFD2_k127_688822_3 Protein of unknown function (DUF3298) - - - 0.00000000000000000208 95.0
HFD2_k127_688822_4 - - - - 0.00000000003201 77.0
HFD2_k127_688822_5 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.0000000004035 64.0
HFD2_k127_688822_6 PFAM SH3 type 3 domain protein - - - 0.000004747 60.0
HFD2_k127_6891096_0 Periplasmic binding protein domain K10559 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 540.0
HFD2_k127_6891096_1 FGGY family of carbohydrate kinases, N-terminal domain K00848,K00879,K01813 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008993,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019200,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046365,GO:0046835,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901575 2.7.1.5,2.7.1.51,5.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 530.0
HFD2_k127_6891096_2 isomerase K01820 - 5.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007876 524.0
HFD2_k127_6891096_3 PFAM Periplasmic binding protein LacI transcriptional regulator K02529,K03604 GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001130,GO:0001131,GO:0001141,GO:0001216,GO:0001217,GO:0002054,GO:0002057,GO:0002060,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006140,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019220,GO:0019222,GO:0030808,GO:0030809,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0036094,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045936,GO:0045980,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0062014,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 289.0
HFD2_k127_6909982_0 Cytochrome b/b6/petB K00412,K03888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002284 252.0
HFD2_k127_6909982_1 Cytochrome b subunit of the bc K03888 - - 0.0000000000000000000000000000009195 132.0
HFD2_k127_6909982_2 Ethylbenzene dehydrogenase - - - 0.00000000000000000000000000005428 127.0
HFD2_k127_6909982_3 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000002461 121.0
HFD2_k127_6914409_0 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 351.0
HFD2_k127_6914409_2 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006134 300.0
HFD2_k127_6914409_3 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000001854 84.0
HFD2_k127_6914840_0 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 334.0
HFD2_k127_6914840_1 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 297.0
HFD2_k127_6914840_10 Transcriptional - - - 0.000000000000000000000004926 104.0
HFD2_k127_6914840_11 Rieske-like [2Fe-2S] domain - - - 0.000000000000000002865 89.0
HFD2_k127_6914840_13 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.000002799 53.0
HFD2_k127_6914840_14 Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin K04085 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00005963 48.0
HFD2_k127_6914840_2 ABC-type sugar transport system periplasmic component K02624,K10439,K10543,K13641,K21602 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 308.0
HFD2_k127_6914840_3 Inositol monophosphatase family K01092,K05602 - 3.1.3.15,3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008149 291.0
HFD2_k127_6914840_4 Binding-protein-dependent transport system inner membrane component K10118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007478 281.0
HFD2_k127_6914840_5 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008638 286.0
HFD2_k127_6914840_6 mannose metabolic process K01191 - 3.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000001857 279.0
HFD2_k127_6914840_7 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004013 249.0
HFD2_k127_6914840_8 WD40 domain protein beta Propeller K03641 - - 0.0000000000000000000000000000000000000000000000002491 194.0
HFD2_k127_6914840_9 heme binding - - - 0.0000000000000000000000000000000000000001117 166.0
HFD2_k127_6915451_0 PFAM WD domain, G-beta repeat - - - 6.047e-218 731.0
HFD2_k127_6915451_1 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 297.0
HFD2_k127_6915451_2 glycerophosphodiester transmembrane transport K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006524 284.0
HFD2_k127_6915451_3 Bacterial transcriptional activator domain - - - 0.0000000000000000000000003166 124.0
HFD2_k127_6915451_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0001178 46.0
HFD2_k127_6923948_0 MBOAT, membrane-bound O-acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000001336 209.0
HFD2_k127_6923948_1 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000008712 131.0
HFD2_k127_6923948_2 4-amino-4-deoxy-L-arabinose transferase activity K16648 - - 0.000000000000003757 89.0
HFD2_k127_6923948_3 Alternative locus ID K07052 - - 0.0001261 53.0
HFD2_k127_692405_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000002554 123.0
HFD2_k127_692405_1 PFAM glycosyl transferase family 39 - - - 0.0000000004791 72.0
HFD2_k127_6929958_0 PFAM glycoside hydrolase, family 4 K01222 - 3.2.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 436.0
HFD2_k127_6929958_1 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 321.0
HFD2_k127_6929958_2 Helix-turn-helix type 11 domain protein K13572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 294.0
HFD2_k127_6929958_3 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000004144 209.0
HFD2_k127_6929958_4 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000000000000000000000000000000000004421 199.0
HFD2_k127_6929958_5 - - - - 0.000000000000000000000000000000000000000000000000000007063 199.0
HFD2_k127_6929958_6 Domain of unknown function (DUF4342) - - - 0.00000000000000000000006937 102.0
HFD2_k127_6929958_7 PFAM dihydropteroate synthase, DHPS K15023 - 2.1.1.258 0.00000000000000000004929 94.0
HFD2_k127_6929958_8 Proteolipid membrane potential modulator - - - 0.000000000000149 72.0
HFD2_k127_6930742_0 Domain of Unknown Function (DUF1206) - - - 0.0000000000000000000000000000000000000000000000000000000001874 214.0
HFD2_k127_6930742_1 cog cog1284 - - - 0.00000000000000000000000000000000000000000000000001335 190.0
HFD2_k127_6930742_2 Aldo Keto reductase - - - 0.0000000000000000000003402 96.0
HFD2_k127_6930742_3 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000002379 94.0
HFD2_k127_6933733_0 PFAM aminotransferase class V K04127 - 5.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 458.0
HFD2_k127_6933733_1 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 301.0
HFD2_k127_6933733_2 PFAM binding-protein-dependent transport systems inner membrane component K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 296.0
HFD2_k127_6933733_3 Domain of unknown function (DUF4832) - - - 0.00003322 54.0
HFD2_k127_6940115_0 SMART Elongator protein 3 MiaB NifB - - - 2.442e-199 631.0
HFD2_k127_6940115_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 576.0
HFD2_k127_6940115_2 Extracellular solute-binding protein K02055 GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008351 573.0
HFD2_k127_6940115_3 positive regulation of transcription, DNA-templated K09684 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 537.0
HFD2_k127_6940115_4 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008947 385.0
HFD2_k127_6940115_5 Glyoxalase-like domain - - - 0.00000000000000000000002009 104.0
HFD2_k127_6946568_0 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 416.0
HFD2_k127_6946568_1 Encoded by - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001087 269.0
HFD2_k127_6956102_0 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 544.0
HFD2_k127_6956102_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000006346 200.0
HFD2_k127_6956506_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 3.705e-241 760.0
HFD2_k127_6956506_1 TIGRFAM molybdenum cofactor synthesis domain K03750,K07219 - 2.10.1.1 5.338e-225 714.0
HFD2_k127_6956506_10 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000000000000000000000000000002817 191.0
HFD2_k127_6956506_11 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00000000000000000000000000000000000008785 155.0
HFD2_k127_6956506_12 HemY domain protein - - - 0.000000000000000000000002384 121.0
HFD2_k127_6956506_13 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000000005446 120.0
HFD2_k127_6956506_14 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00000000000000000008732 93.0
HFD2_k127_6956506_15 Transglutaminase-like superfamily - - - 0.0000000000005573 74.0
HFD2_k127_6956506_16 ABC-type multidrug transport system ATPase and permease K06147 - - 0.00005403 47.0
HFD2_k127_6956506_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K20276 - - 9.166e-213 709.0
HFD2_k127_6956506_3 permease K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 456.0
HFD2_k127_6956506_4 TIGRFAM molybdenum cofactor synthesis domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 439.0
HFD2_k127_6956506_5 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 386.0
HFD2_k127_6956506_6 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008184 353.0
HFD2_k127_6956506_7 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 342.0
HFD2_k127_6956506_8 Protein of unknown function (DUF4038) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 307.0
HFD2_k127_6956506_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000002469 194.0
HFD2_k127_6962891_0 Alpha-L-rhamnosidase N-terminal domain protein K05989 - 3.2.1.40 9.303e-233 736.0
HFD2_k127_6962891_1 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006285 508.0
HFD2_k127_6962891_2 inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 484.0
HFD2_k127_6962891_3 Belongs to the glycosyl hydrolase 43 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 383.0
HFD2_k127_6962891_4 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007484 296.0
HFD2_k127_6996876_0 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 370.0
HFD2_k127_6996876_1 PFAM Polynucleotide adenylyltransferase region K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008839 332.0
HFD2_k127_6996876_2 PFAM oxidoreductase, molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 300.0
HFD2_k127_6996876_3 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000003794 214.0
HFD2_k127_6996876_4 Methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000004114 178.0
HFD2_k127_6996876_5 Tetratricopeptide repeat K20543 - - 0.0008714 46.0
HFD2_k127_7007576_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 5.159e-238 754.0
HFD2_k127_7007576_1 - - - - 0.0000000000000000000000000000000000000000005066 168.0
HFD2_k127_7007576_2 NB-ARC domain - - - 0.000000007922 66.0
HFD2_k127_7012067_0 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 3.052e-253 798.0
HFD2_k127_701418_0 PFAM Branched-chain amino acid transport system permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009692 285.0
HFD2_k127_701418_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000001009 239.0
HFD2_k127_701418_2 - - - - 0.00000000000006565 72.0
HFD2_k127_7019498_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 592.0
HFD2_k127_7019498_1 TIGRFAM isochorismate synthase K02361,K02552 - 5.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 405.0
HFD2_k127_7019498_2 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002188 264.0
HFD2_k127_7026904_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 481.0
HFD2_k127_7026904_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 304.0
HFD2_k127_7026904_2 Transcriptional regulatory protein, C terminal K07668,K07775 - - 0.000000000000000000000000000000000000000000000000000000000000000000008523 242.0
HFD2_k127_703459_0 PFAM ABC transporter transmembrane region - - - 5.865e-248 779.0
HFD2_k127_703459_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000003495 147.0
HFD2_k127_7039500_0 ABC-type sugar transport system, permease component K02026,K10229 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 377.0
HFD2_k127_7039500_1 Belongs to the ABC transporter superfamily K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 327.0
HFD2_k127_7039500_2 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 327.0
HFD2_k127_7039500_3 ABC-type sugar transport systems, permease components K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002546 279.0
HFD2_k127_7043893_0 PFAM extracellular solute-binding protein family 1 K10117,K17315 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 542.0
HFD2_k127_7043893_1 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 533.0
HFD2_k127_7043893_2 ribulose-phosphate 3-epimerase activity K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 421.0
HFD2_k127_7043893_3 transmembrane transport K15771,K17316 - - 0.0000000000000000000000000004854 119.0
HFD2_k127_7047337_0 Rieske-like [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 548.0
HFD2_k127_7047337_1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 515.0
HFD2_k127_7047337_2 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000000000008077 173.0
HFD2_k127_7047337_3 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000002506 112.0
HFD2_k127_7047337_4 COG2963, Transposase and inactivated derivatives - - - 0.0000000001439 63.0
HFD2_k127_7047337_5 PFAM Integrase core domain K07497 - - 0.000002436 52.0
HFD2_k127_7055424_0 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003954 302.0
HFD2_k127_7055424_1 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000009234 140.0
HFD2_k127_7055424_2 PFAM ChaB - - - 0.000000000000000000000000001395 112.0
HFD2_k127_7064870_0 Phosphoribosyl transferase domain K07101 - - 0.00000000000000000000000000000000000000000000000000000000002294 210.0
HFD2_k127_7064870_1 protein conserved in bacteria (DUF2087) - - - 0.00000000000000000000000000000000000000000000000000000000002962 211.0
HFD2_k127_7064870_2 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000006101 196.0
HFD2_k127_7064870_3 radical SAM domain protein K06137,K06138 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000149 205.0
HFD2_k127_7067952_0 Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7' K00231,K00514,K02293,K09879,K21677 - 1.17.8.1,1.3.3.15,1.3.3.4,1.3.5.5,1.3.5.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 408.0
HFD2_k127_7067952_1 Peptidase family S41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000927 383.0
HFD2_k127_7067952_2 Belongs to the ParA family K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009859 330.0
HFD2_k127_7067952_3 Phosphomannose isomerase type I K01809 - 5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000004946 258.0
HFD2_k127_7067952_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13590 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000009102 273.0
HFD2_k127_7067952_5 PHP domain K04486 - 3.1.3.15 0.000000000000000000000000000000000000000000000000000000000000003065 227.0
HFD2_k127_7067952_6 AAA domain K02282 - - 0.0000000000000000000000000002957 118.0
HFD2_k127_7067952_7 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.0000000000000007332 81.0
HFD2_k127_7067952_8 Protein of unknown function (DUF2992) - - - 0.000003059 53.0
HFD2_k127_7067952_9 stress, protein - - - 0.00004024 51.0
HFD2_k127_7070171_0 Cation transporting ATPase, C-terminus K01531 - 3.6.3.2 0.0 1033.0
HFD2_k127_7070171_1 DHH family K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 548.0
HFD2_k127_7070171_10 Calcium binding - - - 0.00000000000000000000000000000000000000000000003427 172.0
HFD2_k127_7070171_11 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000008281 163.0
HFD2_k127_7070171_12 inorganic diphosphatase activity K01507 - 3.6.1.1 0.000000000000000000000000000000000000007324 148.0
HFD2_k127_7070171_13 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000002424 126.0
HFD2_k127_7070171_2 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 536.0
HFD2_k127_7070171_3 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 387.0
HFD2_k127_7070171_4 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 367.0
HFD2_k127_7070171_5 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001605 277.0
HFD2_k127_7070171_6 Aldo Keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003828 274.0
HFD2_k127_7070171_7 Binding-protein-dependent transport system inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008433 262.0
HFD2_k127_7070171_8 Uncharacterized protein family UPF0029 K00560,K01271 - 2.1.1.45,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000002246 226.0
HFD2_k127_7070171_9 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000000006994 190.0
HFD2_k127_707144_0 transcriptional regulator, LuxR family - - - 5.542e-306 955.0
HFD2_k127_707144_1 Ferrous iron transport protein B C terminus K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009255 275.0
HFD2_k127_707144_2 Leg1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000005206 240.0
HFD2_k127_707144_3 - - - - 0.00000000000000000000000000000000000000009882 162.0
HFD2_k127_707144_4 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000003239 163.0
HFD2_k127_707144_5 Protein of unknown function (DUF4038) - - - 0.0000000000000000000000000000000005545 151.0
HFD2_k127_707144_6 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.000000000000000000000000000000005227 148.0
HFD2_k127_707144_7 Ferrous iron transport protein B C terminus K04759 - - 0.00000000000000000000005642 101.0
HFD2_k127_7087561_0 WD-40 repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 650.0
HFD2_k127_7087561_1 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 532.0
HFD2_k127_7087561_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000007382 213.0
HFD2_k127_7087561_3 dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000003627 192.0
HFD2_k127_7087561_4 COG2963 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000005233 141.0
HFD2_k127_7087561_5 transposition, DNA-mediated K02529,K20971 - - 0.000000000000000000000000000000000007573 145.0
HFD2_k127_7087561_6 - - - - 0.000000000000000000000000000003149 124.0
HFD2_k127_7087561_7 COG2801 Transposase and inactivated derivatives - - - 0.0000000000001768 75.0
HFD2_k127_7087561_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000001035 61.0
HFD2_k127_7089946_0 PFAM ABC transporter related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009462 386.0
HFD2_k127_7089946_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 387.0
HFD2_k127_7089946_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 321.0
HFD2_k127_7089946_3 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004666 279.0
HFD2_k127_7089946_4 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000108 271.0
HFD2_k127_7089946_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000005796 89.0
HFD2_k127_7090869_0 domain, Protein - - - 0.0000000000000000000000000003815 130.0
HFD2_k127_7090869_1 Hep Hag repeat protein K11904,K21449 - - 0.000000000000000002274 99.0
HFD2_k127_7090869_2 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000008189 74.0
HFD2_k127_7090869_3 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000002099 53.0
HFD2_k127_7098910_0 Psort location Cytoplasmic, score K01239 - 3.2.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 399.0
HFD2_k127_7098910_1 NADPH:quinone reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 323.0
HFD2_k127_7098910_2 cobalamin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 297.0
HFD2_k127_7099072_0 oxidoreductase activity - - - 0.0000000000000000000000000000000000000001274 172.0
HFD2_k127_7103457_0 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 494.0
HFD2_k127_7106586_0 domain, Protein K08961 - 4.2.2.20,4.2.2.21 0.000000000000000001095 100.0
HFD2_k127_7106586_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000005071 79.0
HFD2_k127_7106586_2 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000005864 62.0
HFD2_k127_7106586_3 serine-type peptidase activity K08676 - - 0.000002216 60.0
HFD2_k127_7123899_0 biotin acetyl-CoA-carboxylase ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000005452 193.0
HFD2_k127_7123899_1 - - - - 0.000001003 53.0
HFD2_k127_7145652_0 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 412.0
HFD2_k127_7145652_1 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006837 278.0
HFD2_k127_7145652_2 histone acetyltransferase, ELP3 family K07739 - 2.3.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000002863 266.0
HFD2_k127_7146941_0 - - - - 0.0000000000006201 78.0
HFD2_k127_7146941_1 PFAM Dual specificity protein phosphatase K14165 - 3.1.3.16,3.1.3.48 0.0000000000008363 78.0
HFD2_k127_7146941_2 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000002625 60.0
HFD2_k127_7147411_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1101.0
HFD2_k127_7147411_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 441.0
HFD2_k127_7147411_2 General stress protein K06884 - - 0.00000000000000000000000000000000001047 138.0
HFD2_k127_7151255_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000007908 254.0
HFD2_k127_7151255_1 Domain of unknown function (DUF4349) - - - 0.000000000000000000000000000000000000000000000000000005923 201.0
HFD2_k127_7151255_2 RNA-binding protein - - - 0.00000000000000000000000739 103.0
HFD2_k127_715591_0 peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000000000000000000000001135 201.0
HFD2_k127_715591_1 Ntpase (Nacht family) K12132 - 2.7.11.1 0.000000000005878 79.0
HFD2_k127_7163930_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 418.0
HFD2_k127_7163930_1 Transcriptional regulatory protein, C terminal K02483,K07669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 336.0
HFD2_k127_7163930_2 Transposase K07492 - - 0.00000000000000000000000000000000000000000000000000000000000000006099 226.0
HFD2_k127_7163930_3 MBOAT, membrane-bound O-acyltransferase family - - - 0.00000000000000000000000000000000000000000000000002189 196.0
HFD2_k127_7163930_4 Multicopper oxidase K00368 - 1.7.2.1 0.000000000000000000000000000000000000005704 153.0
HFD2_k127_7163930_5 Transposase DDE domain K07492 - - 0.0000000000000000000006205 98.0
HFD2_k127_7163930_6 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.0000008465 58.0
HFD2_k127_7163930_7 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.00003292 49.0
HFD2_k127_7163930_8 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.4 0.0000398 49.0
HFD2_k127_7164546_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000608 522.0
HFD2_k127_7164546_1 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 435.0
HFD2_k127_7164546_10 translation initiation factor activity - - - 0.000009967 58.0
HFD2_k127_7164546_2 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000003466 168.0
HFD2_k127_7164546_3 Tricorn protease homolog - - - 0.00000000000000000000000001374 125.0
HFD2_k127_7164546_4 PFAM Forkhead-associated protein - - - 0.00000000000000003571 89.0
HFD2_k127_7164546_5 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000001882 87.0
HFD2_k127_7164546_6 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000001899 87.0
HFD2_k127_7164546_7 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000003046 83.0
HFD2_k127_7164546_8 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000003495 79.0
HFD2_k127_7164546_9 cheY-homologous receiver domain K02657 - - 0.000000006287 63.0
HFD2_k127_7170430_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004988 559.0
HFD2_k127_7170430_1 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 492.0
HFD2_k127_7170430_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000004344 123.0
HFD2_k127_7182428_0 COGs COG3533 conserved K09955 - - 8.125e-212 676.0
HFD2_k127_7182428_1 carbohydrate transport K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005732 461.0
HFD2_k127_7182428_2 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 386.0
HFD2_k127_7182428_3 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 353.0
HFD2_k127_7182428_4 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000000000000000000000000000000000000000000007522 234.0
HFD2_k127_7182428_5 zinc finger - - - 0.0000000000000000000000000000000000000000000000000000000000001185 218.0
HFD2_k127_7182428_6 helix_turn _helix lactose operon repressor K02529 - - 0.0000000001027 63.0
HFD2_k127_7187074_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000001667 154.0
HFD2_k127_7187074_1 PFAM conserved - - - 0.00000000000000000000000000000001697 136.0
HFD2_k127_7193037_0 RNA repair, ligase-Pnkp-associating, region of Hen1 - - - 5.927e-205 646.0
HFD2_k127_7193037_1 Predicted nucleotidyltransferase K07074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 402.0
HFD2_k127_7193037_2 Predicted nucleotidyltransferase K07074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 297.0
HFD2_k127_7198289_0 P-loop Domain of unknown function (DUF2791) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008978 559.0
HFD2_k127_7198289_1 TerB N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005961 266.0
HFD2_k127_7198289_2 DEAD DEAH box helicase K03724 - - 0.00000000000000000000000000000000000000000000000000000001237 206.0
HFD2_k127_7198289_3 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion K02564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.6 0.000000000000000000001114 96.0
HFD2_k127_7201891_0 Belongs to the GcvT family K00302 - 1.5.3.1 5.782e-231 743.0
HFD2_k127_7201891_1 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 511.0
HFD2_k127_7201891_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00034 - 1.1.1.47 0.0000000000000000000000000000000000000000000000003393 183.0
HFD2_k127_7201891_3 Sarcosine oxidase, gamma subunit family K22087 - 1.5.99.5 0.0000002692 60.0
HFD2_k127_7204208_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 487.0
HFD2_k127_7204208_1 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000003083 206.0
HFD2_k127_7204208_2 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000000000000000000000000000005811 164.0
HFD2_k127_7204208_3 SUF system FeS assembly protein, NifU family K04488 - - 0.0000000000000000000000000000000000000000009248 160.0
HFD2_k127_7204208_4 HD domain K07814 - - 0.00000000000000000000004089 115.0
HFD2_k127_7204208_5 RHS Repeat - - - 0.00000006016 66.0
HFD2_k127_7204208_6 COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain K04771 - 3.4.21.107 0.00000009396 64.0
HFD2_k127_7204208_7 COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain K04771 - 3.4.21.107 0.0000003798 63.0
HFD2_k127_7208476_0 Penicillin-Binding Protein C-terminus Family - - - 1.978e-216 701.0
HFD2_k127_7208476_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 354.0
HFD2_k127_7208476_2 sulfuric ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000003736 224.0
HFD2_k127_7208476_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000002065 219.0
HFD2_k127_7208476_4 Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000001653 174.0
HFD2_k127_7208476_5 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0005325 51.0
HFD2_k127_720906_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008995 330.0
HFD2_k127_720906_1 Helix-turn-helix type 11 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 330.0
HFD2_k127_720906_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004307 284.0
HFD2_k127_720906_3 Carotenoid biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000001091 218.0
HFD2_k127_720906_4 Glyoxalase-like domain K08234 - - 0.0000000000000000000000000000000000000000000000000000353 191.0
HFD2_k127_720906_5 membrane - - - 0.000000000000000000000000000000000000462 146.0
HFD2_k127_7214686_0 Glycosyl hydrolase family 115 - - - 3.109e-263 840.0
HFD2_k127_7214686_1 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001818 296.0
HFD2_k127_7214686_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000001013 161.0
HFD2_k127_7214686_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000002415 86.0
HFD2_k127_7214686_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000008965 65.0
HFD2_k127_7214686_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00001492 55.0
HFD2_k127_7215859_0 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 626.0
HFD2_k127_7215859_1 PFAM D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 310.0
HFD2_k127_7217386_0 transposase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 524.0
HFD2_k127_7217386_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 468.0
HFD2_k127_7217386_2 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002789 261.0
HFD2_k127_7217386_3 Integrase core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003004 233.0
HFD2_k127_7217386_4 Rhodanese Homology Domain K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000008862 232.0
HFD2_k127_7217386_5 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000397 191.0
HFD2_k127_7217386_6 Integrase catalytic K07497 - - 0.000000000000004726 84.0
HFD2_k127_7217386_7 Phosphorylase superfamily - - - 0.0000000000003332 78.0
HFD2_k127_7217386_8 Peptidase family M50 K11749 - - 0.00001606 56.0
HFD2_k127_7225270_0 glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich K01190 - 3.2.1.23 0.0 1393.0
HFD2_k127_7225270_1 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 1.372e-313 970.0
HFD2_k127_7225270_10 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000004247 134.0
HFD2_k127_7225270_11 Cytochrome P450 - - - 0.000000000000000000003763 94.0
HFD2_k127_7225270_12 Two component signalling adaptor domain K03408 - - 0.0000000000002788 75.0
HFD2_k127_7225270_13 COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07713 - - 0.00000000007613 73.0
HFD2_k127_7225270_14 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000644 49.0
HFD2_k127_7225270_2 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 590.0
HFD2_k127_7225270_3 ATP-binding region, ATPase domain protein K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 461.0
HFD2_k127_7225270_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000696 276.0
HFD2_k127_7225270_5 PFAM histidine kinase, HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002836 276.0
HFD2_k127_7225270_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000002909 175.0
HFD2_k127_7225270_7 gluconolactonase activity K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000006705 167.0
HFD2_k127_7225270_8 PFAM histidine kinase, HAMP region domain protein - - - 0.000000000000000000000000000000000001283 152.0
HFD2_k127_7225270_9 Ribosomal protein L11 methyltransferase (PrmA) K02169 - 2.1.1.197 0.0000000000000000000000000000000001053 142.0
HFD2_k127_7229485_0 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 328.0
HFD2_k127_7229485_1 Binding-protein-dependent transport systems inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 316.0
HFD2_k127_7229485_2 PFAM Amidohydrolase family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 310.0
HFD2_k127_7229485_3 SIS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001933 252.0
HFD2_k127_7229485_4 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000004473 155.0
HFD2_k127_7229485_5 carbohydrate transport K02027 - - 0.00000000000000000000000000000000000009594 148.0
HFD2_k127_7234776_0 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006535 389.0
HFD2_k127_7237076_0 extracellular solute-binding protein, family 3 K09969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 323.0
HFD2_k127_7237076_1 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K09970 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 319.0
HFD2_k127_7237076_2 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K09971 - - 0.00000000000000000000000005201 116.0
HFD2_k127_7239640_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 557.0
HFD2_k127_7239640_1 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 512.0
HFD2_k127_7239640_2 Belongs to the ClpA ClpB family K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 419.0
HFD2_k127_7239640_3 Peptidase_C39 like family - - - 0.000000000000000000000000000000000000000000000000000000000000001518 239.0
HFD2_k127_7239640_4 TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.00000000000000007799 91.0
HFD2_k127_7239640_5 acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.000008248 57.0
HFD2_k127_7263259_0 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 285.0
HFD2_k127_7263259_1 PFAM Polysaccharide deacetylase - - - 0.00000008366 57.0
HFD2_k127_7263259_2 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000002005 59.0
HFD2_k127_7269053_0 PFAM Major Facilitator Superfamily K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 346.0
HFD2_k127_7269053_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 323.0
HFD2_k127_7269053_2 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001689 256.0
HFD2_k127_7269053_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000002958 224.0
HFD2_k127_7269053_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000001708 135.0
HFD2_k127_7270348_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 345.0
HFD2_k127_7274731_0 L-arabinose isomerase activity K01804 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008733,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.3.1.4 2.346e-239 748.0
HFD2_k127_7274731_1 peptidase dimerisation domain protein K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 303.0
HFD2_k127_7274731_10 DNA gyrase C-terminal domain, beta-propeller - - - 0.00008979 54.0
HFD2_k127_7274731_11 SMART helix-turn-helix domain protein K15539 - - 0.0003923 53.0
HFD2_k127_7274731_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 297.0
HFD2_k127_7274731_3 Hsp70 protein K04046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006334 308.0
HFD2_k127_7274731_4 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000001188 175.0
HFD2_k127_7274731_5 TIGRFAM iron-sulfur cluster assembly accessory protein - - - 0.0000000000000000000000000000000000000009155 151.0
HFD2_k127_7274731_6 PFAM regulatory protein, ArsR - - - 0.00000000000000000000000000000000000003342 151.0
HFD2_k127_7274731_7 Beta-lactamase enzyme family - - - 0.000000000000000000000000000000009091 145.0
HFD2_k127_7274731_8 - - - - 0.00000000001127 75.0
HFD2_k127_7274731_9 aldolase K01624,K03339 - 4.1.2.13,4.1.2.29 0.000001278 59.0
HFD2_k127_7283693_0 PFAM Glycoside hydrolase family 42 domain protein K12308 - 3.2.1.23 4.982e-263 820.0
HFD2_k127_7283693_1 Arabinose transporter permease K17236 - - 0.000000000007118 67.0
HFD2_k127_7289310_0 Heavy-metal-associated domain K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008317 443.0
HFD2_k127_7289310_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000005888 214.0
HFD2_k127_7289310_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000005938 194.0
HFD2_k127_7289310_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000003048 184.0
HFD2_k127_7289310_4 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000234 110.0
HFD2_k127_7289310_5 - - - - 0.0000000008766 63.0
HFD2_k127_7298204_0 molybdopterin cofactor binding K00183 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001265 285.0
HFD2_k127_7298204_1 Fe-S-cluster-containing hydrogenase K00184 - - 0.0000000000000000000000000000000000000000000000000001625 193.0
HFD2_k127_7308756_0 carbohydrate transport K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 385.0
HFD2_k127_7308756_1 transmembrane transport K02025,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 293.0
HFD2_k127_7308756_2 PFAM Bacterial regulatory proteins, gntR family K02103 - - 0.000000000000000000000000000008186 132.0
HFD2_k127_7320066_0 WD domain, G-beta repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 578.0
HFD2_k127_7320066_1 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000007116 240.0
HFD2_k127_7320066_2 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000006547 214.0
HFD2_k127_7320066_3 Caspase domain - - - 0.00000000000000000000000004854 116.0
HFD2_k127_7322368_0 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 526.0
HFD2_k127_7322368_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 357.0
HFD2_k127_7322368_2 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000611 224.0
HFD2_k127_7322368_3 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000009484 188.0
HFD2_k127_7322368_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000009678 187.0
HFD2_k127_7323110_0 - - - - 0.00000000000000000000000000005846 121.0
HFD2_k127_732529_0 FAD dependent oxidoreductase K00109,K15736 - 1.1.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 534.0
HFD2_k127_732529_1 PFAM Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000836 130.0
HFD2_k127_732529_2 PFAM WD domain, G-beta repeat - - - 0.00000000000000001094 94.0
HFD2_k127_732529_3 ketosteroid isomerase - - - 0.000008183 49.0
HFD2_k127_7326814_0 Glycosyl hydrolases family 31 K01811 - 3.2.1.177 2.505e-275 861.0
HFD2_k127_7326814_1 COGs COG1653 ABC-type sugar transport system periplasmic component K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 542.0
HFD2_k127_7326814_10 helix_turn _helix lactose operon repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001616 286.0
HFD2_k127_7326814_11 M6 family metalloprotease domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000043 267.0
HFD2_k127_7326814_12 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000005542 255.0
HFD2_k127_7326814_13 FR47-like protein K03829 - - 0.00000000000000000000000000000000000000000000000000001591 194.0
HFD2_k127_7326814_14 domain, Protein - - - 0.000000000000000000000000000000000000000000006588 190.0
HFD2_k127_7326814_15 3-hexulose-6-phosphate synthase K08093 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.2.43 0.00000000000000000000000000000000000000000002386 170.0
HFD2_k127_7326814_16 6-phospho 3-hexuloisomerase K08094 - 5.3.1.27 0.000000000000000000000000000000000000000006588 160.0
HFD2_k127_7326814_17 Histidine kinase - - - 0.00000000000000000000000000000000001346 145.0
HFD2_k127_7326814_18 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000008258 103.0
HFD2_k127_7326814_19 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000001211 82.0
HFD2_k127_7326814_2 Bacterial extracellular solute-binding protein K10117 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 515.0
HFD2_k127_7326814_20 O-Antigen ligase - - - 0.000000001034 70.0
HFD2_k127_7326814_21 PFAM von Willebrand factor type A K01337 - 3.4.21.50 0.000000001373 73.0
HFD2_k127_7326814_22 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000002117 61.0
HFD2_k127_7326814_23 repeat protein - - - 0.000726 54.0
HFD2_k127_7326814_24 ABC transporter substrate binding protein K01989 - - 0.0007563 48.0
HFD2_k127_7326814_3 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 463.0
HFD2_k127_7326814_4 COGs COG0395 ABC-type sugar transport system permease component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 416.0
HFD2_k127_7326814_5 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 415.0
HFD2_k127_7326814_6 COGs COG1175 ABC-type sugar transport systems permease components K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007492 399.0
HFD2_k127_7326814_7 PFAM binding-protein-dependent transport systems inner membrane component K02025,K10118,K10189,K10233,K15771 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 360.0
HFD2_k127_7326814_8 Binding-protein-dependent transport system inner membrane component K10119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 334.0
HFD2_k127_7326814_9 Glycoside hydrolase family 3 K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 302.0
HFD2_k127_7339911_0 molybdopterin cofactor binding K00183 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 381.0
HFD2_k127_7339911_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000005543 239.0
HFD2_k127_7339911_2 Histidine kinase K07777 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000246 211.0
HFD2_k127_7340071_0 DeoR C terminal sensor domain K02081 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 323.0
HFD2_k127_7340071_1 carbohydrate transport K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003851 263.0
HFD2_k127_7340071_2 Psort location CytoplasmicMembrane, score 10.00 K10118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002 251.0
HFD2_k127_7340071_3 ABC-type sugar transport system, permease component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000004351 248.0
HFD2_k127_7340071_4 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000003992 188.0
HFD2_k127_7340071_5 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000534 97.0
HFD2_k127_735102_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 315.0
HFD2_k127_735102_1 lipoprotein transporter activity K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005548 284.0
HFD2_k127_735102_2 Secretion protein K02005 - - 0.000000000000000000000000000000000004025 155.0
HFD2_k127_735102_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.00000000000000000000000005764 123.0
HFD2_k127_735102_4 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000005856 102.0
HFD2_k127_735102_5 Protein-tyrosine phosphatase K14165 - 3.1.3.16,3.1.3.48 0.0000000002 67.0
HFD2_k127_7354910_0 ATPase AAA-2 domain protein K03696 - - 0.000000000000000007291 94.0
HFD2_k127_7354910_1 amine dehydrogenase activity - - - 0.00000000001727 76.0
HFD2_k127_7354910_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000204 72.0
HFD2_k127_7365489_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 402.0
HFD2_k127_7365489_1 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000002781 98.0
HFD2_k127_7369439_0 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 397.0
HFD2_k127_7369439_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 310.0
HFD2_k127_7369439_2 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002274 280.0
HFD2_k127_7369439_3 Iron-containing redox enzyme K06137 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008307 272.0
HFD2_k127_7369439_4 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000002743 235.0
HFD2_k127_7369439_5 Glutathione S-transferase, N-terminal domain - - - 0.000000000000000000000000000000001047 140.0
HFD2_k127_7369439_6 Winged helix-turn helix - - - 0.00000000000000000000005592 102.0
HFD2_k127_7370966_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 373.0
HFD2_k127_7370966_1 PFAM ABC transporter related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001883 256.0
HFD2_k127_7370966_10 Cysteine-rich secretory protein family - - - 0.0004263 51.0
HFD2_k127_7370966_2 PFAM PfkB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008122 252.0
HFD2_k127_7370966_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000003404 218.0
HFD2_k127_7370966_4 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000171 188.0
HFD2_k127_7370966_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000001791 123.0
HFD2_k127_7370966_7 glycosyl transferase family - - - 0.00000000000000002503 88.0
HFD2_k127_7370966_8 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000001496 78.0
HFD2_k127_7370966_9 cyclic nucleotide binding K10914 GO:0000166,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0017076,GO:0019219,GO:0019222,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000002435 74.0
HFD2_k127_739234_0 COGs COG4886 Leucine-rich repeat (LRR) protein K13730 - - 0.000000007205 68.0
HFD2_k127_7400829_0 Cytochrome C and Quinol oxidase polypeptide I K00404 - 1.9.3.1 1.134e-237 735.0
HFD2_k127_7400829_1 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 463.0
HFD2_k127_7400829_2 SCO1/SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 326.0
HFD2_k127_7400829_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 295.0
HFD2_k127_7405914_0 56kDa selenium binding protein (SBP56) - - - 1.765e-220 686.0
HFD2_k127_7405914_1 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000001121 161.0
HFD2_k127_7405914_3 Conserved repeat domain - - - 0.0000000000000000000000000001998 126.0
HFD2_k127_7419583_0 Recombinase zinc beta ribbon domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 544.0
HFD2_k127_7419583_1 transposition, DNA-mediated K02529,K20971 - - 0.000000000000000004623 86.0
HFD2_k127_7419583_2 transposition, DNA-mediated K02529,K20971 - - 0.0000000000001919 74.0
HFD2_k127_7419583_3 Recombinase zinc beta ribbon domain - - - 0.000000007226 61.0
HFD2_k127_7424244_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000006505 172.0
HFD2_k127_7424244_1 peroxiredoxin activity K03386 - 1.11.1.15 0.0000000000000001787 80.0
HFD2_k127_7425608_0 ABC-type sugar transport system periplasmic component K02058,K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 414.0
HFD2_k127_7425608_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 369.0
HFD2_k127_7425608_2 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 352.0
HFD2_k127_7425608_3 purine nucleotide biosynthetic process K02529 GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042802,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000009766 117.0
HFD2_k127_7425608_4 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000002272 77.0
HFD2_k127_7432767_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 1.458e-230 743.0
HFD2_k127_7432767_1 PFAM response regulator receiver K07667 - - 0.0000000000000000002851 87.0
HFD2_k127_7433023_0 COG1175 ABC-type sugar transport systems, permease components K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001942 284.0
HFD2_k127_7433023_1 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002295 268.0
HFD2_k127_7433023_2 Binding-protein-dependent transport system inner membrane component K02026,K10190 - - 0.00000000000000000000000000000000000000000000000000000000000000000186 237.0
HFD2_k127_7433023_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000008875 98.0
HFD2_k127_7433023_4 CHRD domain - - - 0.000000000000001695 87.0
HFD2_k127_7436599_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004743 250.0
HFD2_k127_7436599_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02484,K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000001435 261.0
HFD2_k127_7436599_2 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000001374 207.0
HFD2_k127_7436599_3 - - - - 0.00000000001681 75.0
HFD2_k127_7440_0 PFAM sodium calcium exchanger membrane region K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 349.0
HFD2_k127_7440_1 PFAM sigma-70 region 2 domain protein K03088 - - 0.00000000000000000000000000000000000000000000000000000003962 203.0
HFD2_k127_7440_2 Nudix hydrolase - - - 0.00000000000000000000000000000000000000001668 165.0
HFD2_k127_7440_3 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.00000000000000000000000000000002778 143.0
HFD2_k127_7440_4 AntiSigma factor - - - 0.000000000002617 79.0
HFD2_k127_7443255_0 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 482.0
HFD2_k127_7443255_2 PFAM O-antigen polymerase - - - 0.0000000000000000000000000000000000000000000000000000000006048 224.0
HFD2_k127_7448416_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K01919,K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 6.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 330.0
HFD2_k127_7448416_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 303.0
HFD2_k127_7450663_0 Bacterial alpha-L-rhamnosidase C-terminal domain K05989 - 3.2.1.40 0.0 1133.0
HFD2_k127_7450663_1 Psort location Cytoplasmic, score 7.50 - - - 0.0 1085.0
HFD2_k127_7450663_2 dipeptide transport K02035 - - 9.229e-250 787.0
HFD2_k127_7450663_3 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 465.0
HFD2_k127_7450663_4 nitrogen compound transport K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 460.0
HFD2_k127_7450663_5 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 414.0
HFD2_k127_7450663_6 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K10824 - 3.6.3.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 357.0
HFD2_k127_7450663_7 F5/8 type C domain - - - 0.000000000000000000000000000000000000000003847 162.0
HFD2_k127_7454416_0 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 368.0
HFD2_k127_7454416_1 Methyltransferase type 11 K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 336.0
HFD2_k127_7454416_2 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005126 307.0
HFD2_k127_7454416_3 hmm pf00144 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 310.0
HFD2_k127_7454416_4 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 289.0
HFD2_k127_7454416_5 RNA polymerase, sigma-24 subunit, ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000005247 168.0
HFD2_k127_7461193_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0 1253.0
HFD2_k127_7461193_1 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 2.51e-241 779.0
HFD2_k127_7461193_2 - - - - 0.00004342 49.0
HFD2_k127_74699_0 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008241 323.0
HFD2_k127_74699_1 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 317.0
HFD2_k127_74699_2 PFAM Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000006988 200.0
HFD2_k127_74699_3 DoxX-like family - - - 0.0000000000000000000000000000000002512 136.0
HFD2_k127_74699_4 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000001578 117.0
HFD2_k127_74699_5 integral membrane protein K00728 - 2.4.1.109 0.00000000000000000000000001518 127.0
HFD2_k127_74699_6 Ribosomal protein S21 K02970 - - 0.000000000000000000891 87.0
HFD2_k127_74699_7 - - - - 0.0000001791 62.0
HFD2_k127_74699_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000006864 51.0
HFD2_k127_7474783_0 Belongs to the IlvD Edd family K22396 GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019520,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0050401,GO:0071704,GO:0072329,GO:1901575 4.2.1.82 2.299e-297 926.0
HFD2_k127_7474783_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 405.0
HFD2_k127_7474783_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000394 273.0
HFD2_k127_7474783_4 ABC-type multidrug transport system ATPase component - - - 0.000000000000000000002816 102.0
HFD2_k127_7474783_5 response regulator K02657,K03413 - - 0.0000000000002599 75.0
HFD2_k127_7474783_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000001353 74.0
HFD2_k127_7474783_7 methyltransferase - - - 0.000000001156 70.0
HFD2_k127_7474783_8 PFAM Septum formation initiator K05589 - - 0.0002475 49.0
HFD2_k127_7474815_0 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000008314 214.0
HFD2_k127_7474815_1 protein kinase activity - - - 0.0000000000000000000000000000000002785 153.0
HFD2_k127_7477217_0 H( )-stimulated, divalent metal cation uptake system K03322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 394.0
HFD2_k127_7477217_1 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 318.0
HFD2_k127_7477217_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007711 279.0
HFD2_k127_7477217_3 Phosphodiester glycosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002588 254.0
HFD2_k127_7477217_4 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000009057 197.0
HFD2_k127_7479588_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000511 361.0
HFD2_k127_7479588_1 Modulates RecA activity K03565 - - 0.00000000000000000000000000000000000000000000000000002468 195.0
HFD2_k127_7479588_2 uridine kinase K00876 - 2.7.1.48 0.000000000000000000000000000000388 125.0
HFD2_k127_7492616_0 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 462.0
HFD2_k127_7492616_1 Pfam:DUF3380 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001347 246.0
HFD2_k127_7493335_0 Winged helix DNA-binding domain K09927 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004938 443.0
HFD2_k127_7493335_1 Flavin containing amine oxidoreductase K15745 - 1.3.99.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 427.0
HFD2_k127_7493335_2 dihydrofolate reductase activity - - - 0.000000000000000000000000000000007905 129.0
HFD2_k127_7493335_3 RNA polymerase K03088 - - 0.000000000000000000004992 100.0
HFD2_k127_7493335_4 self proteolysis - - - 0.00000000000000002273 94.0
HFD2_k127_7493335_5 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000002148 65.0
HFD2_k127_749946_0 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005845 430.0
HFD2_k127_749946_1 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000004389 164.0
HFD2_k127_749946_2 Domain of unknown function (DUF4395) - - - 0.00000000000000000000000000000000000000000171 160.0
HFD2_k127_749946_3 ThiS family K03636 - - 0.00000000000000000000000000000000332 130.0
HFD2_k127_749946_4 COG0526, thiol-disulfide isomerase and thioredoxins K03671 - - 0.000000000000000000002502 98.0
HFD2_k127_7508454_0 diaminopimelate decarboxylase activity K01585,K01586 - 4.1.1.19,4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000506 264.0
HFD2_k127_7508454_1 Streptomycin adenylyltransferase K05593 - - 0.000000000000000000000000000000000000000000000000000001201 203.0
HFD2_k127_7514920_0 PFAM Periplasmic binding protein LacI transcriptional regulator K02529,K03604 GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001130,GO:0001131,GO:0001141,GO:0001216,GO:0001217,GO:0002054,GO:0002057,GO:0002060,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006140,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019220,GO:0019222,GO:0030808,GO:0030809,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0036094,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045936,GO:0045980,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0062014,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 422.0
HFD2_k127_7514920_1 Oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 340.0
HFD2_k127_7514920_2 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 302.0
HFD2_k127_7514920_3 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009269 284.0
HFD2_k127_7514920_4 - - - - 0.000000000000000000000000000000000001633 142.0
HFD2_k127_7514920_5 Major facilitator superfamily - - - 0.0000000000000000000000000000000000018 143.0
HFD2_k127_7514920_6 COG3103 SH3 domain protein K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.0000004113 61.0
HFD2_k127_7525814_0 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 333.0
HFD2_k127_7525814_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 298.0
HFD2_k127_7525814_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 290.0
HFD2_k127_7525814_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000009738 215.0
HFD2_k127_7525814_4 Putative stress-induced transcription regulator - - - 0.00000000000000000000000000000000000000000000005606 177.0
HFD2_k127_7525814_5 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000001072 164.0
HFD2_k127_7525814_6 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000003348 157.0
HFD2_k127_7525814_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000004974 95.0
HFD2_k127_7525814_8 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000005509 84.0
HFD2_k127_7525814_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00006577 52.0
HFD2_k127_7531945_0 PFAM molybdopterin oxidoreductase K00123,K05299 - 1.17.1.10,1.17.1.9 4.068e-233 741.0
HFD2_k127_7531945_1 hydrolase family K01179,K20829 GO:0005575,GO:0005576 3.2.1.176,3.2.1.4 5.313e-194 647.0
HFD2_k127_7531945_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006075 619.0
HFD2_k127_7531945_3 Amino acid permease - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 586.0
HFD2_k127_7531945_4 NB-ARC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 592.0
HFD2_k127_7531945_5 formate dehydrogenase (NAD+) activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 312.0
HFD2_k127_7531945_6 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000002227 216.0
HFD2_k127_7531945_7 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000001006 167.0
HFD2_k127_7531945_8 Cellulose binding domain K01179,K05988 - 3.2.1.11,3.2.1.4 0.000000003994 71.0
HFD2_k127_7531945_9 Cellulose binding domain - - - 0.0001836 55.0
HFD2_k127_7542548_0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 1.238e-266 841.0
HFD2_k127_7542548_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 2.738e-218 696.0
HFD2_k127_7542548_10 Methyltransferase domain - - - 0.0000000000000000000000000001432 126.0
HFD2_k127_7542548_11 transcriptional regulator - - - 0.0000000000000000156 87.0
HFD2_k127_7542548_12 heavy metal translocating P-type ATPase K01533 - 3.6.3.4 0.0001322 50.0
HFD2_k127_7542548_2 PFAM ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 527.0
HFD2_k127_7542548_3 NAD dependent epimerase dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 407.0
HFD2_k127_7542548_4 CO dehydrogenase/acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 406.0
HFD2_k127_7542548_5 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 324.0
HFD2_k127_7542548_6 CobQ/CobB/MinD/ParA nucleotide binding domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008119 265.0
HFD2_k127_7542548_7 PFAM Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000002901 222.0
HFD2_k127_7542548_8 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000007496 216.0
HFD2_k127_7542548_9 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000009346 151.0
HFD2_k127_7543830_0 Berberine and berberine like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 566.0
HFD2_k127_7543830_1 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000003268 214.0
HFD2_k127_7543830_2 Integrase core domain K07497 - - 0.00073 44.0
HFD2_k127_7562510_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008162 328.0
HFD2_k127_7562510_1 ABC transporter K02056 - 3.6.3.17 0.00000000000000000001391 94.0
HFD2_k127_7562510_2 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.00000000000007176 79.0
HFD2_k127_7562510_3 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.00000000004401 71.0
HFD2_k127_7570181_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 6.002e-276 857.0
HFD2_k127_7570181_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 2.105e-228 716.0
HFD2_k127_7570181_2 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000002848 192.0
HFD2_k127_7574379_0 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 462.0
HFD2_k127_7574379_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 376.0
HFD2_k127_7574379_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 350.0
HFD2_k127_7574379_3 PFAM acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005517 322.0
HFD2_k127_7574379_4 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001484 269.0
HFD2_k127_7574379_5 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003056 244.0
HFD2_k127_7574379_6 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00177 - 1.2.7.1,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000003167 215.0
HFD2_k127_7574379_7 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000612 203.0
HFD2_k127_7574379_8 PFAM CBS domain K04767 - - 0.000000000000000000000005619 106.0
HFD2_k127_7574379_9 4Fe-4S ferredoxin iron-sulfur binding domain protein K00176 - 1.2.7.3 0.0000000000000000000002958 98.0
HFD2_k127_7574704_0 transcriptional regulator, LuxR family - - - 9.261e-228 729.0
HFD2_k127_7574704_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 374.0
HFD2_k127_7574704_2 transposition K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 367.0
HFD2_k127_7574704_3 COGs COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 294.0
HFD2_k127_7574704_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000484 257.0
HFD2_k127_7574704_5 Transcriptional regulator - - - 0.000000000000000000000000000000004474 136.0
HFD2_k127_7574704_6 Pfam:DUF385 - - - 0.00000000000000000000000000005846 121.0
HFD2_k127_7574704_7 - - - - 0.000000000001257 71.0
HFD2_k127_7583427_0 Alpha amylase, C-terminal all-beta domain K00700 - 2.4.1.18 1.53e-241 765.0
HFD2_k127_7583427_1 Highly conserved protein containing a thioredoxin domain K02027 - - 5.454e-217 700.0
HFD2_k127_7583427_10 PFAM glycosidase PH1107-related K20885 - 2.4.1.339,2.4.1.340 0.0000000000000000000000000000000008123 132.0
HFD2_k127_7583427_2 carbohydrate transport K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 442.0
HFD2_k127_7583427_3 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 379.0
HFD2_k127_7583427_4 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000391 336.0
HFD2_k127_7583427_5 helix_turn _helix lactose operon repressor K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 293.0
HFD2_k127_7583427_6 PFAM Helix-turn-helix, type 11 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002677 252.0
HFD2_k127_7583427_7 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006479 248.0
HFD2_k127_7583427_8 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000006356 161.0
HFD2_k127_7583427_9 WD domain, G-beta repeat - - - 0.00000000000000000000000000000000000000002618 173.0
HFD2_k127_7585074_0 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 - 4.1.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004622 460.0
HFD2_k127_7585074_1 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily K01911 - 6.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 416.0
HFD2_k127_7585074_2 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 358.0
HFD2_k127_7595580_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 482.0
HFD2_k127_7595580_1 purine nucleotide biosynthetic process K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007876 334.0
HFD2_k127_7595580_10 hydrocarbon binding protein (contains V4R domain) - - - 0.0002104 51.0
HFD2_k127_7595580_11 Family of unknown function (DUF5335) - - - 0.0006907 48.0
HFD2_k127_7595580_2 ABC transporter (Permease) K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003111 248.0
HFD2_k127_7595580_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000007107 224.0
HFD2_k127_7595580_4 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000006021 216.0
HFD2_k127_7595580_5 transmembrane transport K02025,K10201,K15771 - - 0.00000000000000000000000000000000000000000000000000000429 205.0
HFD2_k127_7595580_6 ABC transporter K02027 - - 0.0000000000000000000000000000000000000000000000000003132 202.0
HFD2_k127_7595580_7 ABC-type sugar transport system periplasmic component K10439 - - 0.000000000000000000000000000000000000000000001088 179.0
HFD2_k127_7595580_8 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain K05346 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000008261 169.0
HFD2_k127_7595938_0 N-terminal 7TM region of histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000065 359.0
HFD2_k127_7595938_1 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008298 332.0
HFD2_k127_7595938_2 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000003353 171.0
HFD2_k127_7595938_3 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000001931 128.0
HFD2_k127_7595938_4 acetyltransferase K06889,K19273 - - 0.00000000000000000000000000005759 123.0
HFD2_k127_7595938_5 Domain of unknown function (DUF4340) - - - 0.000000000009815 76.0
HFD2_k127_7603556_0 epimerase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 421.0
HFD2_k127_7603556_1 reverse transcriptase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 293.0
HFD2_k127_7603556_2 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 290.0
HFD2_k127_7603556_3 Fumarylacetoacetate (FAA) hydrolase family K01826 - 5.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001366 283.0
HFD2_k127_7603556_4 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000699 179.0
HFD2_k127_7603556_5 Beta-lactamase enzyme family - - - 0.0000000000000000000000000000000000007219 160.0
HFD2_k127_7603556_6 Domain of unknown function (DUF1992) - - - 0.00000000000716 72.0
HFD2_k127_7603556_7 PFAM nuclease (SNase domain protein) K01174 - 3.1.31.1 0.000000002438 68.0
HFD2_k127_7603556_8 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000001416 68.0
HFD2_k127_7605269_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 505.0
HFD2_k127_7605269_1 FCD - - - 0.000000000000000000000001297 110.0
HFD2_k127_7605269_2 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000009967 95.0
HFD2_k127_7607903_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 6.908e-224 709.0
HFD2_k127_7607903_1 glycerophosphodiester transmembrane transport K02026,K05815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 303.0
HFD2_k127_7607903_2 transmembrane transport K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17242,K17316 - - 0.0000000000000000000000001156 109.0
HFD2_k127_7610165_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 549.0
HFD2_k127_7610165_1 PFAM dehydrogenase E1 component K21416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 471.0
HFD2_k127_7610165_2 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 385.0
HFD2_k127_7610165_3 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000002248 230.0
HFD2_k127_7610165_4 Catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000003937 194.0
HFD2_k127_7615769_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.649e-214 676.0
HFD2_k127_7615769_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 362.0
HFD2_k127_7615769_2 nucleotidyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 298.0
HFD2_k127_7615769_3 - - - - 0.000000001144 68.0
HFD2_k127_7634732_0 Associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 456.0
HFD2_k127_7634732_1 PFAM VWA containing CoxE family protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009212 420.0
HFD2_k127_7634732_2 PFAM short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000009472 184.0
HFD2_k127_7634732_3 - - - - 0.000000000000000000000000000000000004098 141.0
HFD2_k127_7634732_4 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.000000000000000000001009 102.0
HFD2_k127_7639274_0 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003766 293.0
HFD2_k127_7639274_1 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.00000000000000000000000000000000000000000000000000000000000000000000000000002699 282.0
HFD2_k127_7639274_2 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000001659 229.0
HFD2_k127_7648316_0 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K12528 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 481.0
HFD2_k127_7648316_1 inorganic diphosphatase activity K15986 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 312.0
HFD2_k127_7649479_0 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 395.0
HFD2_k127_7649479_1 peptidase dimerisation domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 358.0
HFD2_k127_7649479_10 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000000002265 84.0
HFD2_k127_7649479_11 PFAM Forkhead-associated protein - - - 0.0000000000168 76.0
HFD2_k127_7649479_12 LysM domain - - - 0.0004328 50.0
HFD2_k127_7649479_2 Transcriptional regulatory protein, C terminal K02483,K07667 GO:0008150,GO:0040007 - 0.0000000000000000000000000000000000000000000000000000000007075 210.0
HFD2_k127_7649479_3 ABC transporter related - - - 0.000000000000000000000000000000000000000000000001024 186.0
HFD2_k127_7649479_4 phosphatase activity K07025,K20862,K20866 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0022611,GO:0032502,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.10,3.1.3.102,3.1.3.104 0.0000000000000000000000000000000000002825 148.0
HFD2_k127_7649479_5 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000001849 154.0
HFD2_k127_7649479_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000001219 111.0
HFD2_k127_7649479_7 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000002247 105.0
HFD2_k127_7649479_8 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000002685 87.0
HFD2_k127_7649479_9 Two component transcriptional regulator, winged helix family - - - 0.000000000000003387 88.0
HFD2_k127_76507_0 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000232 207.0
HFD2_k127_76507_1 transferase activity, transferring hexosyl groups K18101 - - 0.0000000000000000000000000000000000000000000000000004665 195.0
HFD2_k127_76507_2 O-Antigen ligase K18814 - - 0.00000006489 65.0
HFD2_k127_7662526_0 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 1.482e-202 662.0
HFD2_k127_7662526_1 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 354.0
HFD2_k127_7662526_10 PFAM LmbE family protein - - - 0.0000000000000000000000000000000000000001389 160.0
HFD2_k127_7662526_11 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000001788 143.0
HFD2_k127_7662526_12 SERine Proteinase INhibitors K13963 - - 0.000000000000000000000000000000000004654 141.0
HFD2_k127_7662526_14 cheY-homologous receiver domain - - - 0.0000000000000000003036 94.0
HFD2_k127_7662526_15 COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 - 6.4.1.4 0.000000000000001345 84.0
HFD2_k127_7662526_16 COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain K04771 - 3.4.21.107 0.000000002862 68.0
HFD2_k127_7662526_2 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 358.0
HFD2_k127_7662526_3 FES K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000001385 263.0
HFD2_k127_7662526_4 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000002073 251.0
HFD2_k127_7662526_5 PFAM Peptidase M1, membrane alanine - - - 0.00000000000000000000000000000000000000000000000000000000001271 227.0
HFD2_k127_7662526_6 Carbamoyl-phosphate synthetase large chain domain protein K01961,K01968,K11263 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.000000000000000000000000000000000000000000000000000000101 200.0
HFD2_k127_7662526_7 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000197 215.0
HFD2_k127_7662526_8 cytochrome c biogenesis protein - - - 0.000000000000000000000000000000000000000000000001732 180.0
HFD2_k127_7662526_9 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000004951 166.0
HFD2_k127_7675785_0 peptidase activity, acting on L-amino acid peptides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 392.0
HFD2_k127_7675785_1 Trypsin-like serine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 302.0
HFD2_k127_7675785_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000009178 84.0
HFD2_k127_7675785_3 ABC transporter substrate-binding protein PnrA-like K02058,K05519,K07335 - - 0.000000001515 67.0
HFD2_k127_7679516_0 PFAM sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000097 373.0
HFD2_k127_7679516_1 protein conserved in cyanobacteria - - - 0.00000000000000000001884 98.0
HFD2_k127_7679516_2 KTSC domain - - - 0.00000000001397 69.0
HFD2_k127_7679516_3 PFAM Bacterial regulatory proteins, tetR family - - - 0.00001091 48.0
HFD2_k127_7680006_0 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009301 404.0
HFD2_k127_7685455_0 Cytochrome P450 K14370 GO:0000166,GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0016999,GO:0017000,GO:0017144,GO:0018130,GO:0019748,GO:0020037,GO:0030638,GO:0030639,GO:0033067,GO:0033068,GO:0036094,GO:0044237,GO:0044249,GO:0044550,GO:0046483,GO:0046906,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901334,GO:1901336,GO:1901360,GO:1901362,GO:1901363,GO:1901576 1.14.13.154 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 437.0
HFD2_k127_7685455_1 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004836 259.0
HFD2_k127_7685455_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001809 248.0
HFD2_k127_7685455_3 Helix-turn-helix domain K01647 - 2.3.3.1 0.0000000000000000000000000000000164 130.0
HFD2_k127_7685455_4 Bacteriocin-protection, YdeI or OmpD-Associated K06878 - - 0.0000003622 52.0
HFD2_k127_7688137_0 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 349.0
HFD2_k127_7688137_1 transposition, DNA-mediated - - - 0.000000000000000000000000000000000000000000000000000001792 197.0
HFD2_k127_7688137_2 Homeodomain-like domain - - - 0.00000000000000000000000000000000000000001954 157.0
HFD2_k127_7688137_3 transposition, DNA-mediated - - - 0.00000000000000000000000000004652 119.0
HFD2_k127_7711555_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005907 413.0
HFD2_k127_7711555_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000001865 104.0
HFD2_k127_7711555_2 Domain of unknown function (DUF4870) K09940 - - 0.000000000004334 75.0
HFD2_k127_7719899_0 MOSC N-terminal beta barrel domain K07140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008752 411.0
HFD2_k127_7719899_1 Uncharacterized protein conserved in bacteria (DUF2332) K01056 - 3.1.1.29 0.000000000000000000000000000000000005433 150.0
HFD2_k127_7719899_2 PFAM DinB family - - - 0.0000003198 59.0
HFD2_k127_7721732_1 - - - - 0.0000000000000000000000000000001342 128.0
HFD2_k127_7721732_2 Alpha/beta hydrolase family - - - 0.000000000000000000000006879 100.0
HFD2_k127_7721732_3 Adenine-specific methyltransferase EcoRI - - - 0.00000000000000000002015 94.0
HFD2_k127_7721732_4 Protein of unknown function (DUF692) - - - 0.0000000000000007919 85.0
HFD2_k127_7721732_5 DNA-templated transcription, initiation K02405 - - 0.00000000000004151 75.0
HFD2_k127_7721732_6 - - - - 0.000003141 53.0
HFD2_k127_7730777_0 MmgE PrpD family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 557.0
HFD2_k127_7730777_1 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 321.0
HFD2_k127_7730777_2 GMP synthase (glutamine-hydrolyzing) activity K01951 - 6.3.5.2 0.00000000000000000001318 100.0
HFD2_k127_7730911_0 Belongs to the glycosyl hydrolase 57 family - - - 0.0 1149.0
HFD2_k127_7730911_1 Glycogen debranching enzyme N terminal - - - 0.0 1060.0
HFD2_k127_7730911_2 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 376.0
HFD2_k127_7731909_0 Domain of unknown function (DUF4350) - - - 0.0000000000000000000000000000000000000000000000001584 192.0
HFD2_k127_7731909_1 Domain of unknown function (DUF4129) - - - 0.0000000000000000000000000000001047 140.0
HFD2_k127_7731909_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000002821 97.0
HFD2_k127_7731909_3 BioY family K03523 - - 0.00000000000000006245 88.0
HFD2_k127_7731909_5 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000006976 79.0
HFD2_k127_7731909_6 Membrane domain of glycerophosphoryl diester phosphodiesterase - - - 0.00000000003222 75.0
HFD2_k127_7733850_0 Beta-eliminating lyase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 381.0
HFD2_k127_7733850_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 332.0
HFD2_k127_7733850_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 323.0
HFD2_k127_7733850_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000004876 236.0
HFD2_k127_7733850_4 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000004335 206.0
HFD2_k127_7733850_5 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000000000000000001646 216.0
HFD2_k127_7733850_6 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000001365 188.0
HFD2_k127_7733850_7 chain release factor K15034 - - 0.000000000000000000000000000000000000000000002176 168.0
HFD2_k127_7733850_8 AAA ATPase domain - - - 0.0000000000000000000000003298 109.0
HFD2_k127_7733850_9 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000311 101.0
HFD2_k127_7735639_0 PFAM amidohydrolase K01464 - 3.5.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008916 513.0
HFD2_k127_7735639_1 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 386.0
HFD2_k127_7737872_0 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000004091 159.0
HFD2_k127_7737872_1 AAA domain K02282 - - 0.0000000000000000004866 91.0
HFD2_k127_7737872_2 - - - - 0.0000000107 62.0
HFD2_k127_7743122_0 helix_turn_helix, Lux Regulon K03556 - - 1.385e-194 639.0
HFD2_k127_7743122_1 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001218 283.0
HFD2_k127_7743122_2 - - - - 0.00000000000000000000000000000000009171 149.0
HFD2_k127_7743122_3 membrane - - - 0.000000000000000004997 93.0
HFD2_k127_7743122_4 membrane - - - 0.00000000000000006905 91.0
HFD2_k127_7743122_5 - - - - 0.0000000000000004231 81.0
HFD2_k127_7743122_6 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000001141 75.0
HFD2_k127_7744383_0 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 1.333e-286 905.0
HFD2_k127_7744383_1 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005746 342.0
HFD2_k127_7744383_10 cheY-homologous receiver domain - - - 0.000000001516 68.0
HFD2_k127_7744383_11 helix_turn_helix, Lux Regulon - - - 0.00000007749 61.0
HFD2_k127_7744383_12 ABC-2 family transporter protein K01992 - - 0.0000003545 62.0
HFD2_k127_7744383_13 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00001111 59.0
HFD2_k127_7744383_2 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 306.0
HFD2_k127_7744383_4 phosphatase activity K07025 - - 0.00000000000000000000000000000000000000000000000000005668 195.0
HFD2_k127_7744383_5 Histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000009757 175.0
HFD2_k127_7744383_6 Trypsin-like peptidase domain K04771 - 3.4.21.107 0.0000000000000000000000000000000000000005868 155.0
HFD2_k127_7744383_7 transmembrane transport K01992,K09696 - - 0.0000000000000000000000000000000000001874 156.0
HFD2_k127_7744383_8 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000004898 142.0
HFD2_k127_7744383_9 small GTP-binding protein K06945 - - 0.00000000000000003451 88.0
HFD2_k127_7748552_0 ABC transporter, ATP-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 424.0
HFD2_k127_7748552_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002575 272.0
HFD2_k127_7748552_2 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000004791 201.0
HFD2_k127_7748552_3 - - - - 0.000000000000000000000000000000000000000000000000001857 190.0
HFD2_k127_7748552_4 Platelet-activating factor acetylhydrolase, isoform II - - - 0.0000000000000000000000000000000000002058 156.0
HFD2_k127_7748552_5 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000004039 112.0
HFD2_k127_7748552_6 Integrase core domain K07497 - - 0.00000000005635 65.0
HFD2_k127_7748552_7 Belongs to the 'phage' integrase family - - - 0.0000001017 57.0
HFD2_k127_7748552_8 antibiotic catabolic process - - - 0.0001312 54.0
HFD2_k127_7748718_0 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 432.0
HFD2_k127_7748718_1 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 336.0
HFD2_k127_7749957_0 PFAM ABC transporter transmembrane region K11085 - - 2.892e-227 722.0
HFD2_k127_7749957_1 Methyltransferase type 12 - - - 0.000000000000000000000000000000000003928 151.0
HFD2_k127_7777359_0 helix-turn-helix- domain containing protein AraC type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 437.0
HFD2_k127_7777359_1 Alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 306.0
HFD2_k127_7777359_11 transposase activity - - - 0.00000000000000000002542 100.0
HFD2_k127_7777359_12 Zinc finger, swim domain protein - - - 0.00000000000000000004907 97.0
HFD2_k127_7777359_13 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000002463 58.0
HFD2_k127_7777359_2 Major facilitator Superfamily - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002169 276.0
HFD2_k127_7777359_3 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008023 251.0
HFD2_k127_7777359_4 - - - - 0.0000000000000000000000000000000000000000000000005384 177.0
HFD2_k127_7777359_5 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000005575 177.0
HFD2_k127_7777359_6 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000000000006721 173.0
HFD2_k127_7777359_7 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000000000000000000000000000000000001896 149.0
HFD2_k127_7777359_8 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000001142 141.0
HFD2_k127_7777359_9 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000009216 104.0
HFD2_k127_7794027_0 COGs COG3127 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 0.0000000000000000000000000000000000000000000006066 188.0
HFD2_k127_7794027_1 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000001748 73.0
HFD2_k127_77945_0 PFAM Pyridoxal-dependent decarboxylase K01580 - 4.1.1.15 3.41e-198 626.0
HFD2_k127_77945_1 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 619.0
HFD2_k127_77945_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002902 273.0
HFD2_k127_77945_3 Domain of unknown function (DUF4180) - - - 0.000000000000000000000000000000000000000000000000000000000001011 214.0
HFD2_k127_77945_4 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.00000000000000000000000000000000000000000001043 171.0
HFD2_k127_77945_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000007332 135.0
HFD2_k127_77945_6 PFAM Dual specificity protein phosphatase - - - 0.0000000000000000000000000003222 123.0
HFD2_k127_77945_7 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.00000000000000000002197 98.0
HFD2_k127_77945_8 - - - - 0.00000000000000001497 90.0
HFD2_k127_77945_9 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.00000002866 59.0
HFD2_k127_779463_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 332.0
HFD2_k127_779463_1 COGs COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000001087 247.0
HFD2_k127_779463_2 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000001289 199.0
HFD2_k127_7796271_0 Aldehyde dehydrogenase family K22445 - 1.2.99.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 374.0
HFD2_k127_7796271_1 - - - - 0.000000000000000000000000000001013 125.0
HFD2_k127_7796271_2 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000004616 77.0
HFD2_k127_7796349_0 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 480.0
HFD2_k127_7796349_1 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 473.0
HFD2_k127_7796349_2 alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 414.0
HFD2_k127_7796349_3 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 364.0
HFD2_k127_7796349_4 Binding-protein-dependent transport system inner membrane component K10229 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 336.0
HFD2_k127_7796349_5 Binding-protein-dependent transport system inner membrane component K10228 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 302.0
HFD2_k127_7796349_6 ABC-type sugar transport system periplasmic component K02027,K10227 - - 0.0000000000000000000000000000000001711 134.0
HFD2_k127_7797240_0 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000003021 181.0
HFD2_k127_7797240_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0001454 46.0
HFD2_k127_7811465_0 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005311 250.0
HFD2_k127_7811465_1 synthase K16167 - - 0.00000000000000000000000000000000000000000000000000000000000000438 236.0
HFD2_k127_7811465_2 methyltransferase - - - 0.000000000000000004088 90.0
HFD2_k127_7836726_0 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000007335 246.0
HFD2_k127_7836726_1 Two component transcriptional regulator, winged helix family K07657 - - 0.00000000000000000000000000000000000000000000000000001549 197.0
HFD2_k127_7836726_2 PFAM TadE family protein K12287 - - 0.00000000000000000000000000000000000000000000000000003597 211.0
HFD2_k127_7836726_3 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000002233 164.0
HFD2_k127_7836726_4 response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000000000007673 122.0
HFD2_k127_785638_0 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 292.0
HFD2_k127_785638_1 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 295.0
HFD2_k127_785638_2 Response regulator receiver - - - 0.000000000000000007667 87.0
HFD2_k127_785638_3 histidine kinase HAMP region domain protein K03406 - - 0.00000000000009177 83.0
HFD2_k127_7861256_0 Oligopeptidase F K08602 - - 4.25e-216 685.0
HFD2_k127_7861256_1 Aldo Keto reductase K05882 - 1.1.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 419.0
HFD2_k127_7861256_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 389.0
HFD2_k127_7861256_3 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009058 302.0
HFD2_k127_7861256_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000001083 158.0
HFD2_k127_7861256_5 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000001477 107.0
HFD2_k127_7861256_6 phosphorelay signal transduction system - - - 0.0000000000000002545 83.0
HFD2_k127_7871020_0 acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 394.0
HFD2_k127_7871020_1 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 381.0
HFD2_k127_7871020_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 343.0
HFD2_k127_7871020_3 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001023 254.0
HFD2_k127_7871020_4 maltose O-acetyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000005798 226.0
HFD2_k127_7871020_5 glycosyl transferase, family 39 - - - 0.00000000208 70.0
HFD2_k127_7873811_0 - - - - 1.964e-275 865.0
HFD2_k127_7873811_1 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 550.0
HFD2_k127_7873811_2 VWA domain containing CoxE-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 527.0
HFD2_k127_7875053_0 with different specificities (related to short-chain alcohol K00034,K00046,K00059 - 1.1.1.100,1.1.1.47,1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000002705 250.0
HFD2_k127_7875053_1 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000002399 119.0
HFD2_k127_7877453_0 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 4.846e-206 649.0
HFD2_k127_7877453_1 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 1.136e-198 631.0
HFD2_k127_7877453_2 Sugar ABC transporter permease K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 362.0
HFD2_k127_7877453_3 Branched-chain amino acid transport system / permease component K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 347.0
HFD2_k127_7877453_4 transcriptional regulator K13641 - - 0.000000000000000000000000000000000000000000000000000000000000000003376 239.0
HFD2_k127_7877453_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000547 75.0
HFD2_k127_7889018_0 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007006 435.0
HFD2_k127_7889018_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000003208 237.0
HFD2_k127_7889018_2 4Fe-4S single cluster domain K06871 - - 0.00000000000000000000000000000000000000000000000000003084 191.0
HFD2_k127_7889018_3 Quinohemoprotein amine dehydrogenase, gamma subunit - - - 0.00000000000000000000000000000000000000001038 155.0
HFD2_k127_7891331_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 547.0
HFD2_k127_7891331_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000429 97.0
HFD2_k127_7895333_0 Peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 342.0
HFD2_k127_7895333_1 PFAM Formylglycine-generating sulfatase enzyme K20333 - - 0.000000008059 69.0
HFD2_k127_7900994_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 2.463e-195 628.0
HFD2_k127_7900994_1 Belongs to the FGGY kinase family K00864 - 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647 530.0
HFD2_k127_7900994_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000001035 117.0
HFD2_k127_7900994_11 Cytochrome c - - - 0.00004585 53.0
HFD2_k127_7900994_2 Domain of unknown function (DUF2088) K22373 - 5.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 426.0
HFD2_k127_7900994_3 Putative sugar-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 397.0
HFD2_k127_7900994_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007429 299.0
HFD2_k127_7900994_5 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000002305 217.0
HFD2_k127_7900994_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000003377 193.0
HFD2_k127_7900994_7 L-fucose isomerase, C-terminal domain - - - 0.00000000000000000000000000000000000001757 145.0
HFD2_k127_7900994_8 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.0000000000000000000000000000000000001036 149.0
HFD2_k127_7900994_9 Cytochrome b(C-terminal)/b6/petD - - - 0.000000000000000000000000000000000002686 147.0
HFD2_k127_7909010_0 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 510.0
HFD2_k127_7909010_1 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000001072 174.0
HFD2_k127_7909010_2 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000003137 168.0
HFD2_k127_7909010_3 Chromate resistance exported protein - - - 0.0000000000000000000000000000007142 122.0
HFD2_k127_7909010_4 Low molecular weight phosphatase family - - - 0.0000000000000322 78.0
HFD2_k127_7925838_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 561.0
HFD2_k127_7925838_1 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000001108 57.0
HFD2_k127_7932616_0 - - - - 1.284e-220 701.0
HFD2_k127_7932616_1 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002347 271.0
HFD2_k127_7932616_2 PFAM nuclease (SNase domain protein) K01174 - 3.1.31.1 0.0000000000000000000000000000000000000000000000000000000005567 206.0
HFD2_k127_7932616_3 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000002978 136.0
HFD2_k127_7932616_4 CsbD-like - - - 0.0000000000000000000000002846 106.0
HFD2_k127_7932616_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000002084 100.0
HFD2_k127_7932616_6 PFAM WD domain, G-beta repeat - - - 0.0002804 50.0
HFD2_k127_7937997_0 tRNA synthetases class I (C) catalytic domain K01883 - 6.1.1.16 1.343e-205 648.0
HFD2_k127_7937997_1 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 293.0
HFD2_k127_7937997_2 Methyl-accepting chemotaxis protein (MCP) signaling domain K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000001369 245.0
HFD2_k127_7937997_3 Transcriptional regulatory protein, C terminal K07775 - - 0.00000000000000003823 86.0
HFD2_k127_7937997_4 Protein of unknown function (DUF3352) - - - 0.0000001577 64.0
HFD2_k127_7938873_0 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000000000000000000000000000000000000000001717 231.0
HFD2_k127_7938873_1 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.0000000000000000000000000000000000000002335 159.0
HFD2_k127_7938873_2 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.000000000000000004033 86.0
HFD2_k127_793925_0 B-1 B cell differentiation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001654 264.0
HFD2_k127_7941280_0 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 595.0
HFD2_k127_7941280_1 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 468.0
HFD2_k127_7941280_2 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 338.0
HFD2_k127_7941280_3 CHAD - - - 0.00000000000000000000000000000000000000000000004221 184.0
HFD2_k127_7941280_4 - - - - 0.000000000004325 79.0
HFD2_k127_7941280_5 Acetyltransferase (GNAT) domain - - - 0.0000000003748 72.0
HFD2_k127_7941280_6 PFAM Forkhead-associated protein - - - 0.0000000715 55.0
HFD2_k127_7943538_0 PFAM Methicillin resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003938 282.0
HFD2_k127_7943538_1 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000000000000005859 220.0
HFD2_k127_7943538_2 - - - - 0.0000000000000000000000000000000000000000000000002812 194.0
HFD2_k127_7943538_3 Tetratricopeptide TPR_2 repeat protein - - - 0.0000006119 60.0
HFD2_k127_7955907_0 Thiamine pyrophosphate protein TPP binding domain protein K01652 - 2.2.1.6 1.129e-238 750.0
HFD2_k127_7955907_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 484.0
HFD2_k127_7955907_2 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000003576 164.0
HFD2_k127_7955907_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000003267 124.0
HFD2_k127_7961285_0 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008981 271.0
HFD2_k127_7961285_1 Putative esterase K07017 - - 0.000000000000000000000000001131 123.0
HFD2_k127_7961285_2 Histidine kinase - - - 0.00000000000002822 74.0
HFD2_k127_7962313_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000003488 247.0
HFD2_k127_7962313_1 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000287 164.0
HFD2_k127_7962313_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000005566 83.0
HFD2_k127_7963807_0 ATPases associated with a variety of cellular activities K10562 - 3.6.3.17 1.792e-202 642.0
HFD2_k127_7963807_1 Class ii aldolase K01628,K01629 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008994,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019323,GO:0042802,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0071704,GO:1901575 4.1.2.17,4.1.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 351.0
HFD2_k127_7963807_2 Branched-chain amino acid transport system / permease component K10440,K10556,K10560 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 350.0
HFD2_k127_7963807_3 DEAD DEAH box helicase domain protein K06877 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 300.0
HFD2_k127_7963807_4 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.00000000000000000000000000000000000000000000000000000003759 203.0
HFD2_k127_7963807_5 Class ii aldolase K01628,K03077 - 4.1.2.17,5.1.3.4 0.0000000000000000000000000000000000000000000002285 175.0
HFD2_k127_7963807_6 Belongs to the carbohydrate kinase PfkB family. LacC subfamily K00882 - 2.7.1.56 0.00000000000000000000000000000000000000000004475 172.0
HFD2_k127_7963807_7 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000002037 128.0
HFD2_k127_7963807_8 Branched-chain amino acid transport system / permease component K10561 - - 0.000000274 55.0
HFD2_k127_7963807_9 Leucine rich repeat variant - - - 0.00000499 57.0
HFD2_k127_796486_0 Histidine kinase-like ATPases - - - 5.626e-211 678.0
HFD2_k127_796486_1 mandelate racemase muconate lactonizing K01684 - 4.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007765 540.0
HFD2_k127_796486_10 iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000000000000001579 215.0
HFD2_k127_796486_11 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000007046 201.0
HFD2_k127_796486_12 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000003177 162.0
HFD2_k127_796486_13 Amidohydrolase family - - - 0.0000000000000000000000000000000000000007171 163.0
HFD2_k127_796486_14 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system K19166 - - 0.000000000000000000000000000000000000009332 146.0
HFD2_k127_796486_15 transcription regulator containing HTH domain - - - 0.00000000000000000000000173 104.0
HFD2_k127_796486_16 Periplasmic binding protein K01999 - - 0.000000000000000002885 99.0
HFD2_k127_796486_17 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.0000000000000001263 86.0
HFD2_k127_796486_18 PFAM peptidase S1 and S6 chymotrypsin Hap K04771 - 3.4.21.107 0.000000000007487 78.0
HFD2_k127_796486_19 TIR domain - - - 0.000000002255 68.0
HFD2_k127_796486_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 467.0
HFD2_k127_796486_20 Prolyl oligopeptidase family - - - 0.000401 53.0
HFD2_k127_796486_21 PFAM periplasmic binding protein K02016 - - 0.0006108 48.0
HFD2_k127_796486_22 TIGRFAM lysine biosynthesis protein LysW K05826 - - 0.000695 46.0
HFD2_k127_796486_23 Domain of unknown function (DUF4405) - - - 0.0007219 46.0
HFD2_k127_796486_3 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 361.0
HFD2_k127_796486_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 339.0
HFD2_k127_796486_5 Two component transcriptional regulator, winged helix family K07669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 319.0
HFD2_k127_796486_6 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 296.0
HFD2_k127_796486_7 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000809 307.0
HFD2_k127_796486_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003051 282.0
HFD2_k127_796486_9 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000002326 226.0
HFD2_k127_797223_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 622.0
HFD2_k127_797223_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 604.0
HFD2_k127_797223_10 PFAM membrane protein of K08972 - - 0.00000000000000000000001372 104.0
HFD2_k127_797223_11 Belongs to the Fur family K03711 - - 0.000000000000000005115 89.0
HFD2_k127_797223_12 FeoA K04758 - - 0.00000001255 62.0
HFD2_k127_797223_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007759 428.0
HFD2_k127_797223_3 Class II Aldolase and Adducin N-terminal domain K03077 - 5.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008927 306.0
HFD2_k127_797223_4 Hypothetical methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001747 245.0
HFD2_k127_797223_5 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000001208 238.0
HFD2_k127_797223_6 PFAM formylmethanofuran dehydrogenase, subunit E region K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000001032 239.0
HFD2_k127_797223_7 PFAM PfkB domain protein K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000006005 228.0
HFD2_k127_797223_8 Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000001629 148.0
HFD2_k127_797223_9 Belongs to the Fur family K03711 - - 0.0000000000000000000000000008415 122.0
HFD2_k127_7972731_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 334.0
HFD2_k127_7972731_1 PFAM ABC transporter transmembrane region K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000001347 239.0
HFD2_k127_7973122_0 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000001887 128.0
HFD2_k127_7973122_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000195 119.0
HFD2_k127_7975554_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 460.0
HFD2_k127_7975554_1 PFAM regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000000000000001768 198.0
HFD2_k127_7975554_2 Laminin G domain - - - 0.00000000000000000000000933 114.0
HFD2_k127_7976414_0 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 6.148e-207 651.0
HFD2_k127_7976414_1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 540.0
HFD2_k127_7976414_2 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 342.0
HFD2_k127_7976414_3 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000001076 201.0
HFD2_k127_7976414_4 PFAM HNH endonuclease - - - 0.000000000000000000000000000000000000009872 151.0
HFD2_k127_7976414_5 Thioredoxin-like - - - 0.0002316 45.0
HFD2_k127_7982254_0 cytochrome P450 - - - 0.0000000165 59.0
HFD2_k127_7982254_1 Acetyltransferase (GNAT) domain - - - 0.000007682 55.0
HFD2_k127_7982254_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0008835 45.0
HFD2_k127_7988824_0 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 493.0
HFD2_k127_7988824_1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 453.0
HFD2_k127_7988824_2 ATP phosphoribosyltransferase catalytic region K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 312.0
HFD2_k127_7988824_3 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006021 299.0
HFD2_k127_7988824_4 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000204 245.0
HFD2_k127_7988824_5 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000005575 161.0
HFD2_k127_7988824_6 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000001705 166.0
HFD2_k127_7988824_7 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000001601 123.0
HFD2_k127_7990038_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 413.0
HFD2_k127_7993157_0 ABC transporter transmembrane region K06148,K16013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 607.0
HFD2_k127_7993157_1 PFAM DNA mismatch repair protein MutS domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008196 597.0
HFD2_k127_7993157_2 Cysteine export CydDC family ABC transporter permease subunit ATP-binding protein CydC K16012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 589.0
HFD2_k127_7993157_3 Acyl-CoA dehydrogenase, C-terminal domain K16173 - 1.3.99.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 531.0
HFD2_k127_7993157_4 Aminoglycoside/hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.0000000000000000000000000000000000000000000000736 179.0
HFD2_k127_7993157_5 Acyl CoA acetate 3-ketoacid CoA K01040 - 2.8.3.12 0.0000000000000000000000000000001645 132.0
HFD2_k127_7993157_6 (FHA) domain - - - 0.0000004742 60.0
HFD2_k127_7993157_7 GDSL-like Lipase/Acylhydrolase - - - 0.00009787 45.0
HFD2_k127_7993324_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1125.0
HFD2_k127_7993324_1 4Fe-4S ferredoxin K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 319.0
HFD2_k127_7993324_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000855 320.0
HFD2_k127_7993324_3 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009649 299.0
HFD2_k127_7993324_4 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000004144 222.0
HFD2_k127_7993324_5 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000001161 225.0
HFD2_k127_7993324_6 Protein involved in formate dehydrogenase formation K02380 - - 0.00000000000000000000000000000000000000000405 168.0
HFD2_k127_7993324_7 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.00000000000000000002759 95.0
HFD2_k127_7993324_8 TIGRFAM MoaD family protein K03636 - - 0.000000000009154 69.0
HFD2_k127_7994462_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 4.495e-267 845.0
HFD2_k127_7994462_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000004994 203.0
HFD2_k127_7994462_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000003491 107.0
HFD2_k127_7994462_3 Acetyltransferase (GNAT) domain - - - 0.000000000000004437 87.0
HFD2_k127_7994462_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000002863 58.0
HFD2_k127_7996034_0 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 556.0
HFD2_k127_7996034_1 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 488.0
HFD2_k127_7996034_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000007044 256.0
HFD2_k127_7996034_3 DoxX K16937 - 1.8.5.2 0.000000000000000000000000000000000000000000000000000000006112 207.0
HFD2_k127_7996034_4 PFAM Tetratricopeptide repeat - - - 0.00000002972 57.0
HFD2_k127_7998158_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000002214 199.0
HFD2_k127_7998158_1 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000104 166.0
HFD2_k127_7998158_2 hydrolase activity, acting on ester bonds K01563 - 3.8.1.5 0.0000000000000000000000003974 116.0
HFD2_k127_7998158_3 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.0000001184 64.0
HFD2_k127_8000552_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007794 248.0
HFD2_k127_8000552_1 Phosphoribosyl transferase domain K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000002297 188.0
HFD2_k127_8000552_2 Participates in initiation and elongation during chromosome replication K02314,K02316,K17680 - 3.6.4.12 0.000000000000000000000000000000000000000006179 161.0
HFD2_k127_8000552_3 KaiC - - - 0.000000000003296 73.0
HFD2_k127_80030_0 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006349 432.0
HFD2_k127_80030_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000000000000002032 186.0
HFD2_k127_80030_2 DinB family - - - 0.0000000000000000000000000000000000000000001817 161.0
HFD2_k127_80030_3 YCII-related domain - - - 0.000000000000000000000001419 109.0
HFD2_k127_8006421_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001797 244.0
HFD2_k127_8006421_1 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) - - - 0.00000000000000000000000000000000000000000000000000004833 196.0
HFD2_k127_8010747_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 520.0
HFD2_k127_8010747_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 401.0
HFD2_k127_8010747_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006904 272.0
HFD2_k127_8010747_3 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001978 254.0
HFD2_k127_8010747_4 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000007351 222.0
HFD2_k127_8010747_5 PFAM Roadblock LC7 family protein K07131 - - 0.00000000000000000000000000000000000000000000000804 173.0
HFD2_k127_8015927_0 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000001942 119.0
HFD2_k127_8015927_1 CHRD domain - - - 0.0000000000000004449 88.0
HFD2_k127_8027290_0 Predicted Permease Membrane Region K07085 - - 0.00000000000000000000000000000000000000000000000000000000000000000002357 243.0
HFD2_k127_8027290_1 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000007116 230.0
HFD2_k127_8027290_2 von willebrand factor, type A K12549 - - 0.0000008595 63.0
HFD2_k127_8030414_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001816 245.0
HFD2_k127_8030414_1 Trypsin-like serine protease - - - 0.00000000000000000000000000000000000000000000000000000000000009828 224.0
HFD2_k127_8030414_2 - - - - 0.0003331 51.0
HFD2_k127_8032694_0 Fibronectin type III-like domain K05349 - 3.2.1.21 3.875e-287 900.0
HFD2_k127_8032694_1 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 505.0
HFD2_k127_8032694_2 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 483.0
HFD2_k127_8032694_3 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 412.0
HFD2_k127_8032694_4 glycerophosphodiester transmembrane transport K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007961 383.0
HFD2_k127_8032694_5 transmembrane transport K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17242,K17316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 340.0
HFD2_k127_8032694_6 transmembrane transport K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17242,K17316 - - 0.00000000000000000000000000000000000000000000000000000000000000000002713 237.0
HFD2_k127_8032694_7 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000006238 165.0
HFD2_k127_8032694_8 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K18917 - 1.20.4.3 0.0000000000000000000004158 100.0
HFD2_k127_8032694_9 shape-determining protein MreD K03571 - - 0.000000003131 64.0
HFD2_k127_8041407_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001032 277.0
HFD2_k127_8041407_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000004025 197.0
HFD2_k127_8041407_2 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.0000000000000000000000000000000000000000000000000001326 195.0
HFD2_k127_8041407_3 arsR family transcriptional regulator K21903 - - 0.0000000000000000000000002577 109.0
HFD2_k127_8041407_4 peptidyl-tyrosine sulfation - - - 0.000001308 60.0
HFD2_k127_8045737_0 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 344.0
HFD2_k127_8045737_1 MaoC like domain - - - 0.00000000000000000000000000000000000000000001237 168.0
HFD2_k127_8045737_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000009931 158.0
HFD2_k127_8048564_0 Glycosyl transferase family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 302.0
HFD2_k127_8048564_1 Haloacid dehalogenase-like hydrolase K01560,K07025 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000007049 214.0
HFD2_k127_8048564_2 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000001635 165.0
HFD2_k127_8048564_3 aldo keto reductase - - - 0.0000000000000000000000007214 108.0
HFD2_k127_8048564_4 PFAM Transglycosylase associated protein - - - 0.00000000000000000001118 94.0
HFD2_k127_8051585_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 423.0
HFD2_k127_8051585_1 PFAM regulatory protein TetR - - - 0.000000000000000008548 90.0
HFD2_k127_8051585_2 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000003955 68.0
HFD2_k127_8073987_0 L-fucose isomerase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 518.0
HFD2_k127_8073987_1 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 493.0
HFD2_k127_8073987_2 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 386.0
HFD2_k127_8073987_3 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 385.0
HFD2_k127_8075878_0 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.0 1501.0
HFD2_k127_8078731_0 Carbamoyl-phosphate synthetase large chain domain protein K01955 - 6.3.5.5 0.0 1302.0
HFD2_k127_8078731_1 acetyltransferase - - - 0.000000000000000000000000000000000000000000004732 173.0
HFD2_k127_8078731_2 cell envelope-related transcriptional attenuator - - - 0.000000000000000000000000000000000000000002023 177.0
HFD2_k127_8078731_3 Type IV pilus biogenesis stability protein PilW - - - 0.0001529 54.0
HFD2_k127_808544_0 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 610.0
HFD2_k127_808544_1 DnaJ molecular chaperone homology domain - - - 0.0000001318 62.0
HFD2_k127_8095611_0 HI0933-like protein K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 465.0
HFD2_k127_8095611_1 Bacterial membrane protein YfhO - - - 0.00000000000000000000000000000000000000000000000004011 203.0
HFD2_k127_8095611_2 Belongs to the universal stress protein A family - - - 0.000000000001713 74.0
HFD2_k127_8095611_3 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000004938 63.0
HFD2_k127_8095611_4 Endonuclease/Exonuclease/phosphatase family - - - 0.000002042 53.0
HFD2_k127_8096522_0 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000553 190.0
HFD2_k127_8096522_1 PFAM methyltransferase - - - 0.000000000000000000000002176 113.0
HFD2_k127_8096802_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 8.255e-203 646.0
HFD2_k127_8096802_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000971 434.0
HFD2_k127_8096802_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 404.0
HFD2_k127_8096802_3 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008631 396.0
HFD2_k127_8096802_4 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 349.0
HFD2_k127_8096802_5 ATPases associated with a variety of cellular activities K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 303.0
HFD2_k127_8096802_6 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001299 260.0
HFD2_k127_8096802_7 acr, cog1399 K07040 - - 0.000000000000000000000000000274 121.0
HFD2_k127_8096802_8 O-antigen polymerase K18814 - - 0.00000005781 64.0
HFD2_k127_8102381_0 Baseplate J-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 523.0
HFD2_k127_8102381_1 Phage late control gene D protein (GPD) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 394.0
HFD2_k127_8102381_2 - K06903 - - 0.0000000000000000000000000000002342 126.0
HFD2_k127_8110442_0 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K10824 - 3.6.3.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 490.0
HFD2_k127_8110442_1 Alpha amylase, catalytic domain K00690,K05343 - 2.4.1.7,3.2.1.1,5.4.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 462.0
HFD2_k127_8110442_2 purine nucleotide biosynthetic process K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000108 241.0
HFD2_k127_8110442_3 Transposase IS66 family K07484 - - 0.0000000000000000000000000000000000000000000000000006798 194.0
HFD2_k127_8110442_4 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.0000000000000000002075 88.0
HFD2_k127_8110442_5 PFAM transposase IS66 K07484 - - 0.000009006 55.0
HFD2_k127_8113370_0 helix_turn_helix, Lux Regulon K03556 - - 2.549e-211 675.0
HFD2_k127_8113370_1 - - - - 0.000000000000000009857 93.0
HFD2_k127_8113370_2 DDE superfamily endonuclease - - - 0.0000532 49.0
HFD2_k127_8122789_0 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 606.0
HFD2_k127_8122789_1 Uncharacterized membrane protein (DUF2298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 381.0
HFD2_k127_8122789_2 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001926 241.0
HFD2_k127_8122789_3 SMART Chromosomal replication initiator DnaA domain - - - 0.00000000000000000000000002977 117.0
HFD2_k127_8122789_4 membrane-bound mannosyltransferase - - - 0.0004424 53.0
HFD2_k127_8124726_0 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009221 609.0
HFD2_k127_8124726_1 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 391.0
HFD2_k127_8124726_2 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 337.0
HFD2_k127_8124726_3 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006643 326.0
HFD2_k127_8124726_4 Extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000002755 170.0
HFD2_k127_8124726_5 FGGY family of carbohydrate kinases, C-terminal domain K00851 - 2.7.1.12 0.0000000000000000005258 92.0
HFD2_k127_8133505_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 304.0
HFD2_k127_8133505_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000006826 185.0
HFD2_k127_8134722_0 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.0 1037.0
HFD2_k127_8134722_1 Bacterial protein of unknown function (DUF839) - - - 0.0003381 48.0
HFD2_k127_8140900_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000001422 140.0
HFD2_k127_8140900_1 Phosphodiester glycosidase - - - 0.0000002726 61.0
HFD2_k127_8140900_2 Protein of unknown function (DUF2817) - - - 0.0000004728 59.0
HFD2_k127_8140900_3 sh3 domain protein K01448,K04771,K08884 - 2.7.11.1,3.4.21.107,3.5.1.28 0.00001266 56.0
HFD2_k127_8150723_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000007115 214.0
HFD2_k127_8150723_1 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000000000000000000000000116 214.0
HFD2_k127_8150723_2 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000002303 96.0
HFD2_k127_8159936_0 UDP binding domain K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 551.0
HFD2_k127_8159936_1 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008769 419.0
HFD2_k127_8159936_10 - - - - 0.0000000000000000000000007529 108.0
HFD2_k127_8159936_11 PFAM Glycosyl transferase, group 1 - - - 0.0000000000005159 81.0
HFD2_k127_8159936_12 Calcineurin-like phosphoesterase K07098 - - 0.000000001963 66.0
HFD2_k127_8159936_13 ABC transporter permease K02004,K16918 - - 0.0000003119 59.0
HFD2_k127_8159936_14 Belongs to the peptidase M24B family K01271,K01274 - 3.4.13.9 0.000004971 55.0
HFD2_k127_8159936_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 389.0
HFD2_k127_8159936_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 393.0
HFD2_k127_8159936_4 UDP-glucose 4-epimerase activity K01784,K08679,K17947 - 5.1.3.2,5.1.3.25,5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 332.0
HFD2_k127_8159936_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000009457 254.0
HFD2_k127_8159936_6 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000001881 232.0
HFD2_k127_8159936_7 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000005081 196.0
HFD2_k127_8159936_8 PFAM Glycosyl transferase, group 1 K13668 - 2.4.1.346 0.0000000000000000000000000000001821 138.0
HFD2_k127_8159936_9 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000005952 127.0
HFD2_k127_8161196_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 2.405e-237 745.0
HFD2_k127_8161196_1 N-Acetylmuramoyl-L-alanine amidase - - - 0.0000000007033 72.0
HFD2_k127_8161196_2 Peptidase family M23 - - - 0.00000001494 68.0
HFD2_k127_8161196_3 Putative peptidoglycan binding domain - - - 0.0000003167 63.0
HFD2_k127_8163167_0 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008765 384.0
HFD2_k127_8163167_1 Multicopper oxidase K00368 - 1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000003111 273.0
HFD2_k127_8163167_2 PFAM PfkB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002421 264.0
HFD2_k127_8163167_3 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000001329 249.0
HFD2_k127_8163167_4 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000009919 170.0
HFD2_k127_8163167_5 dipeptidyl-peptidase activity - - - 0.00000000005601 73.0
HFD2_k127_8163167_6 COG0745 Response regulators consisting of a CheY-like receiver K02483 - - 0.000000003976 65.0
HFD2_k127_8163167_7 Phosphopantetheine attachment site - - - 0.00000007383 58.0
HFD2_k127_8163167_8 Gcn5-related n-acetyltransferase - - - 0.00000922 57.0
HFD2_k127_816395_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 596.0
HFD2_k127_816395_1 inositol 2-dehydrogenase activity K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 376.0
HFD2_k127_816395_2 Oxidoreductase family, C-terminal alpha beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 345.0
HFD2_k127_816395_3 PFAM Binding-protein-dependent transport system inner membrane component K10118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 335.0
HFD2_k127_816395_4 ABC transporter (Permease K02026,K10119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 334.0
HFD2_k127_8166935_0 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 405.0
HFD2_k127_8166935_1 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 282.0
HFD2_k127_8166935_2 PFAM Bacterial regulatory proteins, lacI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001377 276.0
HFD2_k127_8166935_3 cheY-homologous receiver domain - - - 0.0000000000000000000003467 103.0
HFD2_k127_8182580_0 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 312.0
HFD2_k127_8182580_1 carbohydrate binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009328 291.0
HFD2_k127_8182580_2 Putative cyclase - - - 0.000000000000000000000001019 112.0
HFD2_k127_819121_0 - - - - 0.000000000000000000000000000000000000000000000000000000000001223 219.0
HFD2_k127_819121_1 WD domain, G-beta repeat - - - 0.00000000000000000000000151 116.0
HFD2_k127_819121_2 GNAT acetyltransferase - - - 0.000000000000000004886 94.0
HFD2_k127_819121_3 - - - - 0.0000000000000007312 79.0
HFD2_k127_8195695_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 1.655e-203 650.0
HFD2_k127_8195695_1 NUBPL iron-transfer P-loop NTPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 376.0
HFD2_k127_8195695_2 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 343.0
HFD2_k127_8195695_3 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000283 131.0
HFD2_k127_8199361_0 ATPase associated with various cellular activities, AAA_5 K03696 - - 0.0 1211.0
HFD2_k127_8199361_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003606 271.0
HFD2_k127_8199361_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000004232 158.0
HFD2_k127_8199361_3 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000002158 135.0
HFD2_k127_8199361_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000002129 90.0
HFD2_k127_8199361_5 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0000002152 61.0
HFD2_k127_8202062_0 Inosine-uridine preferring nucleoside hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004925 422.0
HFD2_k127_8202062_1 PFAM NAD dependent epimerase dehydratase family K01784,K08678 - 4.1.1.35,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 355.0
HFD2_k127_8202062_2 ATPase domain of DNA mismatch repair MUTS family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 339.0
HFD2_k127_8202062_3 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 312.0
HFD2_k127_8202062_4 RNA 2'-phosphotransferase, Tpt1 / KptA family K07559 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 283.0
HFD2_k127_8202062_5 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004662 284.0
HFD2_k127_8202062_6 NUDIX domain - - - 0.000000000000000000001141 99.0
HFD2_k127_8202062_7 Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily K11423 GO:0000003,GO:0000018,GO:0000228,GO:0000428,GO:0000785,GO:0000790,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006275,GO:0006325,GO:0006351,GO:0006353,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006464,GO:0006476,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009058,GO:0009059,GO:0009653,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009987,GO:0010452,GO:0010467,GO:0010468,GO:0010520,GO:0010556,GO:0010558,GO:0010564,GO:0010604,GO:0010605,GO:0010629,GO:0010638,GO:0010639,GO:0010948,GO:0016043,GO:0016070,GO:0016278,GO:0016279,GO:0016569,GO:0016570,GO:0016571,GO:0016575,GO:0016591,GO:0016740,GO:0016741,GO:0018022,GO:0018023,GO:0018024,GO:0018027,GO:0018130,GO:0018193,GO:0018205,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019953,GO:0022402,GO:0022413,GO:0022414,GO:0030154,GO:0030174,GO:0030435,GO:0030437,GO:0030880,GO:0031056,GO:0031057,GO:0031058,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031399,GO:0031400,GO:0031401,GO:0031974,GO:0031981,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032502,GO:0032505,GO:0032774,GO:0032991,GO:0033043,GO:0033044,GO:0034293,GO:0034641,GO:0034645,GO:0034654,GO:0034968,GO:0035065,GO:0035066,GO:0035067,GO:0035601,GO:0036211,GO:0040020,GO:0042054,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0043934,GO:0043935,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0044703,GO:0045128,GO:0045786,GO:0045835,GO:0045892,GO:0045910,GO:0045934,GO:0046483,GO:0046975,GO:0048468,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051253,GO:0051276,GO:0051321,GO:0051445,GO:0051447,GO:0051704,GO:0051726,GO:0051783,GO:0051784,GO:0055029,GO:0060194,GO:0060195,GO:0060255,GO:0060631,GO:0061695,GO:0065007,GO:0070013,GO:0071440,GO:0071441,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090329,GO:0097198,GO:0097659,GO:0097676,GO:0098732,GO:0110029,GO:0140096,GO:1900049,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901983,GO:1901984,GO:1901985,GO:1902275,GO:1902494,GO:1902679,GO:1903046,GO:1903506,GO:1903507,GO:1905268,GO:1905269,GO:1990234,GO:2000112,GO:2000113,GO:2000241,GO:2000242,GO:2000615,GO:2000616,GO:2000756,GO:2000757,GO:2000758,GO:2001141,GO:2001251,GO:2001252 2.1.1.43 0.00000001745 64.0
HFD2_k127_8202062_9 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00003188 55.0
HFD2_k127_8213018_0 PFAM Enoyl-CoA hydratase isomerase K07516 - 1.1.1.35 1.651e-213 685.0
HFD2_k127_8213018_1 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009395 527.0
HFD2_k127_8213018_2 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 414.0
HFD2_k127_8213018_3 Transcriptional regulator - - - 0.00000000000000000000004717 106.0
HFD2_k127_8213046_0 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000005667 160.0
HFD2_k127_8220223_0 polysaccharide catabolic process - - - 2.297e-199 632.0
HFD2_k127_8220223_1 Fibronectin type III-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 402.0
HFD2_k127_8220223_2 PFAM IS1 transposase - - - 0.00002578 47.0
HFD2_k127_8220223_3 Transposase - - - 0.0009967 46.0
HFD2_k127_8227614_0 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000001224 251.0
HFD2_k127_8227614_1 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.00000000000000000000000000000000000000000001587 182.0
HFD2_k127_8227614_2 DUF218 domain - - - 0.00000001733 61.0
HFD2_k127_8234228_0 protein kinase activity - - - 0.000000000000000009656 95.0
HFD2_k127_8234228_1 Protein kinase domain K08884,K12132 - 2.7.11.1 0.00007875 57.0
HFD2_k127_8234956_0 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000001864 271.0
HFD2_k127_8234956_1 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005386 267.0
HFD2_k127_8234956_2 Periplasmic binding proteins and sugar binding domain of LacI family K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000001211 247.0
HFD2_k127_8234956_3 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000002152 174.0
HFD2_k127_8234956_4 - - - - 0.00000000000000000000000000000008739 127.0
HFD2_k127_8234956_5 ABC-type sugar transport system periplasmic component K10439 - - 0.00000000000000000003766 106.0
HFD2_k127_8234956_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0007801 47.0
HFD2_k127_8243775_0 protein histidine kinase activity K01768,K11527,K18143 - 2.7.13.3,4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 499.0
HFD2_k127_8243775_1 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000005873 233.0
HFD2_k127_8243775_2 PFAM response regulator receiver - - - 0.00000000000000000000000000000000003626 138.0
HFD2_k127_8243775_3 PFAM response regulator receiver - - - 0.00000000000000000000003572 104.0
HFD2_k127_8243775_4 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000003245 106.0
HFD2_k127_8244513_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 473.0
HFD2_k127_8244513_1 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 357.0
HFD2_k127_8244513_2 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000003044 216.0
HFD2_k127_8244513_3 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000004177 149.0
HFD2_k127_8244513_4 Belongs to the glycosyl hydrolase 26 family - - - 0.0000000000008461 70.0
HFD2_k127_8246257_0 Carboxypeptidase regulatory-like domain - - - 0.0 1230.0
HFD2_k127_8246257_1 Carboxypeptidase regulatory-like domain - - - 0.000002986 50.0
HFD2_k127_8257841_0 phosphoribosylaminoimidazole carboxylase K11808 - 4.1.1.21 9.681e-194 627.0
HFD2_k127_8257841_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 375.0
HFD2_k127_8257841_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000003959 215.0
HFD2_k127_8257841_3 glyoxalase III activity - - - 0.00000000000000000004066 94.0
HFD2_k127_8257841_4 glyoxalase III activity - - - 0.000000000002895 71.0
HFD2_k127_8257841_5 Psort location Cytoplasmic, score - - - 0.000000001932 63.0
HFD2_k127_8262656_0 glutamine synthetase K01915 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 585.0
HFD2_k127_8262656_1 SMART serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000378 248.0
HFD2_k127_8262656_2 Putative auto-transporter adhesin, head GIN domain - - - 0.00000000000000000000000783 111.0
HFD2_k127_8271215_0 Cellulase (glycosyl hydrolase family 5) - - - 0.000000001745 70.0
HFD2_k127_8271215_1 Transcriptional regulator - - - 0.00000001622 65.0
HFD2_k127_8272556_0 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 336.0
HFD2_k127_8272556_1 cellulase activity - - - 0.00000000000000000000000000005196 124.0
HFD2_k127_8275806_0 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 306.0
HFD2_k127_8275806_1 iron ion homeostasis K02012 - - 0.00000000000000000000000000000000003958 144.0
HFD2_k127_8275806_2 Extracellular solute-binding protein - - - 0.000000000000002723 84.0
HFD2_k127_8275806_3 Peptidase family C69 K14358 - - 0.00000294 51.0
HFD2_k127_8275806_4 Integrase catalytic - - - 0.0001275 48.0
HFD2_k127_8285790_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000006765 218.0
HFD2_k127_8285790_1 peptidase activity - - - 0.000000000000000000000000000001431 132.0
HFD2_k127_8285790_2 Nucleotidyltransferase domain - - - 0.00000000000000000000000000005574 121.0
HFD2_k127_8285790_3 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000003111 101.0
HFD2_k127_8285790_4 Trypsin-like peptidase domain K08372 - - 0.00000000000000000000354 109.0
HFD2_k127_8285790_5 PFAM cyclic nucleotide-binding - - - 0.00000000000000007562 90.0
HFD2_k127_8285790_6 PFAM SH3 type 3 domain protein - - - 0.0000000711 58.0
HFD2_k127_8291023_0 helix_turn_helix, Lux Regulon - - - 0.00000000003904 68.0
HFD2_k127_8291023_1 Periplasmic component of the Tol biopolymer transport system K03641 - - 0.00000004157 65.0
HFD2_k127_8291023_2 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000008911 52.0
HFD2_k127_8293840_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 489.0
HFD2_k127_8293840_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000004511 129.0
HFD2_k127_8304651_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 9.999e-217 687.0
HFD2_k127_8304651_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000004331 239.0
HFD2_k127_8304651_2 Cytochrome C oxidase subunit II, transmembrane domain - - - 0.0000000000000000000000000000000000000000000000000000000000000214 228.0
HFD2_k127_8304651_3 acetyltransferase - - - 0.00000000000000000000000009426 112.0
HFD2_k127_8304651_4 Heme copper-type cytochrome quinol oxidase subunit 3 K02276 - 1.9.3.1 0.000000000000000000000002909 110.0
HFD2_k127_8304651_5 protein kinase activity - - - 0.0000000004245 73.0
HFD2_k127_8304651_6 - - - - 0.000002293 52.0
HFD2_k127_8305225_0 pfam abc K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 349.0
HFD2_k127_8305225_1 Saccharopine dehydrogenase NADP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000576 345.0
HFD2_k127_8305225_2 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005499 276.0
HFD2_k127_8305225_3 Two component transcriptional regulator, winged helix family K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000000002926 236.0
HFD2_k127_8305225_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000004975 224.0
HFD2_k127_8305225_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.00000000000000000000000000000000000000000000000000000263 198.0
HFD2_k127_8305225_6 DinB superfamily - - - 0.00000000000000000000000000000000000383 144.0
HFD2_k127_8306537_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 535.0
HFD2_k127_8306537_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007752 293.0
HFD2_k127_8306537_10 Binding-protein-dependent transport system inner membrane component K10237 - - 0.00000000889 58.0
HFD2_k127_8306537_2 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000002073 242.0
HFD2_k127_8306537_3 Calcineurin-like phosphoesterase K07099 - - 0.00000000000000000000000000000000000000000000000000000000000001209 224.0
HFD2_k127_8306537_4 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000001293 223.0
HFD2_k127_8306537_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000004881 221.0
HFD2_k127_8306537_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000001756 217.0
HFD2_k127_8306537_7 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000004791 175.0
HFD2_k127_8306537_8 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000002936 113.0
HFD2_k127_8306537_9 TIR domain K12132 - 2.7.11.1 0.000000000000000000005331 103.0
HFD2_k127_8309433_0 ABC transporter K10562 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009726 410.0
HFD2_k127_8309433_1 ABC transporter permease protein K10440 - - 0.0000000000000000000000000000000000000000000000000002844 197.0
HFD2_k127_8309433_2 Carbohydrate kinase - - - 0.0000000000000000000000000000001621 138.0
HFD2_k127_8309433_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.6.1.16 0.00000000000000000003352 104.0
HFD2_k127_8309433_4 Phosphoglycerate mutase family K02226,K22316 - 3.1.26.4,3.1.3.73 0.000000000000000001058 92.0
HFD2_k127_8319484_0 Belongs to the GPI family K01810 GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 1.111e-264 824.0
HFD2_k127_8319484_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.598e-202 638.0
HFD2_k127_8319484_2 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009205 455.0
HFD2_k127_8319484_3 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 433.0
HFD2_k127_8319484_4 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 350.0
HFD2_k127_8319484_5 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000009373 218.0
HFD2_k127_8319484_7 Virulence factor BrkB K07058 - - 0.0000000000000000001446 100.0
HFD2_k127_8320265_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239 - 1.3.5.1,1.3.5.4 7.941e-242 759.0
HFD2_k127_8320265_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 436.0
HFD2_k127_8320265_2 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006886 329.0
HFD2_k127_8320265_3 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000222 262.0
HFD2_k127_8320265_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000008837 164.0
HFD2_k127_8320265_5 transport system involved in gliding motility, auxiliary K01992 - - 0.00000000000000000000000000000008911 142.0
HFD2_k127_8320265_6 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.00000000000000000000000004593 118.0
HFD2_k127_8320265_7 membrane K11622 - - 0.0001148 53.0
HFD2_k127_832729_0 ABC transporter K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009755 398.0
HFD2_k127_832729_1 Periplasmic binding protein domain K02058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 341.0
HFD2_k127_832729_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 334.0
HFD2_k127_832729_3 Oxidoreductase family, C-terminal alpha beta domain K16043 - 1.1.1.370 0.000000000000000000000000000000001096 134.0
HFD2_k127_832729_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000001648 114.0
HFD2_k127_8335251_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 457.0
HFD2_k127_8335251_1 YceI-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009303 321.0
HFD2_k127_8335251_2 PFAM Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.000000000000000000000000000000000000006386 148.0
HFD2_k127_8335530_0 Transposase K07481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 401.0
HFD2_k127_8335530_1 FtsJ-like methyltransferase K06968 - 2.1.1.186 0.00000000000000000000000000000000000000000000000000000000002667 218.0
HFD2_k127_8335530_2 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000000000000000002754 125.0
HFD2_k127_8343018_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1308.0
HFD2_k127_8343018_1 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 2.182e-197 627.0
HFD2_k127_8343018_10 - - - - 0.0005617 48.0
HFD2_k127_8343018_2 PFAM Adenosine AMP deaminase K01488 - 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005756 334.0
HFD2_k127_8343018_3 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 322.0
HFD2_k127_8343018_4 regulation of circadian rhythm K08482 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007414 268.0
HFD2_k127_8343018_5 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005388 245.0
HFD2_k127_8343018_6 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001522 235.0
HFD2_k127_8343018_7 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000007305 233.0
HFD2_k127_8343018_8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.000000000000000000000000000000000000001717 159.0
HFD2_k127_8343018_9 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000002421 134.0
HFD2_k127_8348825_0 Conserved hypothetical protein 698 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 447.0
HFD2_k127_8348825_1 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.0000000000000000000000000000000000000000000000000000000000000005213 226.0
HFD2_k127_8348825_2 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000001994 225.0
HFD2_k127_8348825_3 Methyltransferase type 11 K00570 - 2.1.1.17,2.1.1.71 0.0000000000000000000000000000000001979 141.0
HFD2_k127_8348825_4 DNA-binding transcription factor activity K03892 - - 0.000000000000000000001109 98.0
HFD2_k127_8354693_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 374.0
HFD2_k127_8354693_1 Binding-protein-dependent transport system inner membrane component K15581 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 305.0
HFD2_k127_8354693_2 N-terminal TM domain of oligopeptide transport permease C K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000001375 241.0
HFD2_k127_8354693_3 AAA domain - - - 0.000000000000000000000000000000000000000000000001255 192.0
HFD2_k127_8360418_0 ABC-type dipeptide transport system periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 509.0
HFD2_k127_8360418_1 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000002878 113.0
HFD2_k127_8360418_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000007623 108.0
HFD2_k127_8361979_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 368.0
HFD2_k127_8361979_2 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000009161 170.0
HFD2_k127_8361979_3 cobalamin binding - - - 0.00000000000000002297 83.0
HFD2_k127_836637_0 8-amino-7-oxononanoate synthase activity K00639,K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 527.0
HFD2_k127_836637_1 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 511.0
HFD2_k127_836637_2 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 406.0
HFD2_k127_836637_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009943 306.0
HFD2_k127_836637_4 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009661 304.0
HFD2_k127_836637_5 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 291.0
HFD2_k127_836637_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001539 260.0
HFD2_k127_836637_7 Cold-shock K03704 - - 0.00000000000000000000001626 101.0
HFD2_k127_836637_8 Polymer-forming cytoskeletal - - - 0.00000000000000000003811 102.0
HFD2_k127_836637_9 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0000000000007957 69.0
HFD2_k127_8374629_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 562.0
HFD2_k127_8374629_1 glutamate synthase K00265 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 529.0
HFD2_k127_8374629_2 TIGRFAM iron-sulfur cluster binding protein K18929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 464.0
HFD2_k127_8374629_3 Cysteine-rich domain K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003908 257.0
HFD2_k127_8375517_0 Transposase DDE domain group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000504 247.0
HFD2_k127_8375517_1 - - - - 0.0000000000000000004619 100.0
HFD2_k127_8375517_2 Psort location Cytoplasmic, score K06919 - - 0.00007244 48.0
HFD2_k127_837899_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000001185 240.0
HFD2_k127_837899_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000163 236.0
HFD2_k127_837899_2 Histidine kinase K00936,K02030 - 2.7.13.3 0.0000000000000000492 97.0
HFD2_k127_837899_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07716 - 2.7.13.3 0.00000000000004963 77.0
HFD2_k127_8382711_0 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000000000001803 227.0
HFD2_k127_8382711_1 Uracil DNA glycosylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000355 203.0
HFD2_k127_8382711_2 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000006978 183.0
HFD2_k127_8382711_3 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000001817 153.0
HFD2_k127_8382711_4 Belongs to the carbohydrate kinase PfkB family K00882 - 2.7.1.56 0.0000000000000000000000000000000001843 146.0
HFD2_k127_8382711_5 Biotin-requiring enzyme - - - 0.0000000000000000000000000000003408 128.0
HFD2_k127_8382711_6 Roadblock/LC7 domain K07131 - - 0.000000003243 63.0
HFD2_k127_8382711_7 Psort location Extracellular, score 9.55 - - - 0.00000003196 63.0
HFD2_k127_8382711_8 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0002952 53.0
HFD2_k127_8418542_0 YjbR - - - 0.0000000000000000000000000000000000000001895 153.0
HFD2_k127_8418542_1 - - - - 0.000000000000000000000000008931 123.0
HFD2_k127_8418542_2 Integrase core domain K07497 - - 0.000000006681 61.0
HFD2_k127_8418542_3 anaphase-promoting complex binding K03088 - - 0.00000284 54.0
HFD2_k127_8419850_0 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 346.0
HFD2_k127_8419850_1 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004218 264.0
HFD2_k127_8427051_0 NUBPL iron-transfer P-loop NTPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 331.0
HFD2_k127_8427051_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000002915 237.0
HFD2_k127_8427051_2 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000007588 165.0
HFD2_k127_8427051_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000001571 123.0
HFD2_k127_8427051_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000119 81.0
HFD2_k127_8427051_5 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.000000004156 69.0
HFD2_k127_8430494_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 445.0
HFD2_k127_8430494_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 375.0
HFD2_k127_8430494_10 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000002131 76.0
HFD2_k127_8430494_11 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000001091 67.0
HFD2_k127_8430494_12 Nucleoside 2-deoxyribosyltransferase like - - - 0.0001084 52.0
HFD2_k127_8430494_2 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 334.0
HFD2_k127_8430494_3 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001613 274.0
HFD2_k127_8430494_4 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000001523 233.0
HFD2_k127_8430494_5 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000001828 230.0
HFD2_k127_8430494_6 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000212 218.0
HFD2_k127_8430494_7 protein histidine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000594 215.0
HFD2_k127_8430494_8 transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000001718 189.0
HFD2_k127_8430494_9 Parallel beta-helix repeats K12287 - - 0.0000000000000000000000000000000000001127 162.0
HFD2_k127_8451342_0 glycosyl hydrolase 38 domain protein K01191 - 3.2.1.24 5e-324 1009.0
HFD2_k127_8451342_1 Cellobiose phosphorylase - - - 0.00000008851 56.0
HFD2_k127_8465267_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 349.0
HFD2_k127_8467000_0 Insecticidal toxin complex - - - 0.0 1667.0
HFD2_k127_8470142_0 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441,K10562,K17215 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 336.0
HFD2_k127_8470142_1 Branched-chain amino acid transport system / permease component K10440 - - 0.0000000000000000000000000000000000000001032 159.0
HFD2_k127_8484859_0 PFAM periplasmic binding protein LacI transcriptional regulator K02058,K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007353 330.0
HFD2_k127_8484859_1 Amidohydrolase family - - - 0.0003224 51.0
HFD2_k127_8487469_0 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008716 446.0
HFD2_k127_8487469_1 Dehydrogenase E1 component K00166 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 342.0
HFD2_k127_8487469_2 SMART PAS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001865 271.0
HFD2_k127_8487469_3 Ribosomal protein L11 methyltransferase (PrmA) K00564 - 2.1.1.172 0.00000000000000000000000000000000000000000008034 173.0
HFD2_k127_8487469_4 PFAM Transketolase central region K00167 - 1.2.4.4 0.000000000000000000000000000000003267 130.0
HFD2_k127_8487469_5 Uncharacterised protein family UPF0066 - - - 0.0000000000000003939 82.0
HFD2_k127_8487469_6 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000005983 72.0
HFD2_k127_8487469_7 Uncharacterised protein family UPF0066 - - - 0.00000003237 57.0
HFD2_k127_8491311_0 PFAM cobalbumin biosynthesis protein K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000000000000003507 197.0
HFD2_k127_8491311_1 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000008888 181.0
HFD2_k127_8491311_2 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000000026 152.0
HFD2_k127_8491311_3 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000002298 157.0
HFD2_k127_8491311_4 Bacterial membrane protein, YfhO - - - 0.00000000000000000000000000002446 134.0
HFD2_k127_8492665_1 - - - - 0.000000001353 59.0
HFD2_k127_849677_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 587.0
HFD2_k127_849677_1 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 508.0
HFD2_k127_849677_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 463.0
HFD2_k127_849677_3 PFAM ROK family protein K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 321.0
HFD2_k127_849677_4 belongs to the phosphoglycerate kinase family K00927,K01803 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000006844 178.0
HFD2_k127_849677_5 Domain of unknown function DUF11 - - - 0.0000000000000000000000000000000000000327 152.0
HFD2_k127_849677_6 domain protein - - - 0.000000000000000000161 104.0
HFD2_k127_849677_7 guanyl-nucleotide exchange factor activity K01387,K07114,K12287 - 3.4.24.3 0.000000000000000001965 100.0
HFD2_k127_8499270_0 PFAM UbiA prenyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003334 286.0
HFD2_k127_8499270_1 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003488 279.0
HFD2_k127_8499270_2 PFAM GHMP kinase K00869 - 2.7.1.36 0.00000000000000003176 85.0
HFD2_k127_8503052_0 Amino acid permease - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009207 482.0
HFD2_k127_8503052_1 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000004165 208.0
HFD2_k127_8503052_2 Histidine kinase K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000003352 210.0
HFD2_k127_8507534_0 ABC-type sugar transport system periplasmic component K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 398.0
HFD2_k127_8507534_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 381.0
HFD2_k127_8507534_2 import. Responsible for energy coupling to the transport system K10441 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034219,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 365.0
HFD2_k127_8507534_3 Branched-chain amino acid transport system / permease component K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001163 274.0
HFD2_k127_8507534_4 ABC-3 protein K09819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009867 252.0
HFD2_k127_8507534_5 PFAM ABC transporter related K09820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002962 250.0
HFD2_k127_8507534_6 PFAM RNA binding S1 domain protein K02945 - - 0.000000000000000000000000000000000000000000000000008236 190.0
HFD2_k127_8507534_7 Acetyltransferase (GNAT) family - - - 0.00000000000000000000001942 107.0
HFD2_k127_8507534_8 Transcriptional regulatory protein, C terminal K07776 - - 0.0000000000000000004006 91.0
HFD2_k127_8508361_0 Caspase domain - - - 1.564e-209 673.0
HFD2_k127_8508361_1 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000163 282.0
HFD2_k127_8508361_2 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000002304 230.0
HFD2_k127_8508361_3 Caspase domain - - - 0.000000000000000000000000000000000000000000000000000002136 218.0
HFD2_k127_8508361_4 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000186 145.0
HFD2_k127_8508361_5 - - - - 0.0000000000001128 73.0
HFD2_k127_8514391_0 ABC transporter transmembrane region K06147 - - 4.87e-206 648.0
HFD2_k127_8536545_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 3.99e-228 721.0
HFD2_k127_8536545_1 cellular manganese ion homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 337.0
HFD2_k127_8536545_2 nucleotidyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000002727 224.0
HFD2_k127_8550193_0 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03546,K03547 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 341.0
HFD2_k127_8550193_1 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001275 278.0
HFD2_k127_8550193_2 PFAM amine oxidase K02293 - 1.3.5.5 0.00000000000000000000000000000000000000000000000000000000000001875 222.0
HFD2_k127_8550193_3 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000006109 193.0
HFD2_k127_8550193_4 TIGRFAM lycopene cyclase domain K22502 - 5.5.1.19 0.00000000000000000795 89.0
HFD2_k127_8550193_5 Membrane K22502 - 5.5.1.19 0.0000000000000001031 85.0
HFD2_k127_8550193_6 Polysaccharide deacetylase - - - 0.0000000000008277 79.0
HFD2_k127_8562036_0 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 396.0
HFD2_k127_8562036_1 Peptidase M16 domain protein K07263 - - 0.0000000000000000000000000000000000000000000000852 175.0
HFD2_k127_8562036_2 Participates in transcription elongation, termination and antitermination K02601,K05785 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0008996 43.0
HFD2_k127_8563157_0 ATPase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004388 274.0
HFD2_k127_8563157_1 Belongs to the Nudix hydrolase family - - - 0.000000000000003023 83.0
HFD2_k127_8563157_2 - - - - 0.0004454 49.0
HFD2_k127_8576671_0 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 321.0
HFD2_k127_8576671_1 ABC 3 transport family K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 292.0
HFD2_k127_8576671_2 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000003291 229.0
HFD2_k127_8576671_3 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000001804 145.0
HFD2_k127_8576671_4 deoxyhypusine monooxygenase activity - - - 0.000000000000001269 82.0
HFD2_k127_8576671_5 AAA ATPase K07478 - - 0.0000002924 53.0
HFD2_k127_8580437_0 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000005345 185.0
HFD2_k127_8580437_1 AAA domain - - - 0.00000000003355 74.0
HFD2_k127_8593847_0 TIGRFAM metal dependent phophohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000003059 231.0
HFD2_k127_8593847_1 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.0000000000000000000000000000000000000000000000000009032 197.0
HFD2_k127_8593847_2 O-methyltransferase activity K00545 - 2.1.1.6 0.000000000000000000000000000000000000000000000000001959 192.0
HFD2_k127_8593847_3 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000000000000000007957 156.0
HFD2_k127_8593847_4 Methionine biosynthesis protein MetW K18827 - 2.1.1.294,2.7.1.181 0.000000000000000000000000000003962 131.0
HFD2_k127_8593847_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000001826 114.0
HFD2_k127_8595585_0 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 546.0
HFD2_k127_8595585_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003513 272.0
HFD2_k127_8595585_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000009905 84.0
HFD2_k127_8595585_4 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000005675 74.0
HFD2_k127_8595585_5 COG0456 Acetyltransferases K03789 - 2.3.1.128 0.000000000002765 75.0
HFD2_k127_8595585_6 PFAM YcfA-like protein - - - 0.00000000001096 68.0
HFD2_k127_8597282_0 Alpha-L-fucosidase C-terminal domain K01206 - 3.2.1.51 6.959e-198 627.0
HFD2_k127_8597282_1 PFAM periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 302.0
HFD2_k127_8597282_2 hydrolase, family 65, central catalytic K15923 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000007561 197.0
HFD2_k127_8597282_3 PFAM extracellular solute-binding protein family 1 K02027 - - 0.0000004761 55.0
HFD2_k127_8598308_0 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000002528 177.0
HFD2_k127_8598308_1 Hep Hag repeat protein - - - 0.0000000000000000000000006368 114.0
HFD2_k127_8598308_2 Sulfatase-modifying factor enzyme 1 K02396,K03651 - 3.1.4.53 0.00000000000000000002869 100.0
HFD2_k127_8598743_0 Stage II sporulation protein M - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 345.0
HFD2_k127_8598743_1 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 331.0
HFD2_k127_8598743_2 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 315.0
HFD2_k127_8598743_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000001929 194.0
HFD2_k127_8598743_4 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - - - 0.00000000000000000000000000000000000006266 149.0
HFD2_k127_8598743_5 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000002694 138.0
HFD2_k127_8599676_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 8.882e-279 870.0
HFD2_k127_8608837_0 PFAM Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 406.0
HFD2_k127_8608837_1 Secreted repeat of unknown function - - - 0.0000000000000000000000000000000000000000000000000000000000000000002476 246.0
HFD2_k127_8608837_2 DinB family - - - 0.0000000000000000000000000000000000000000000000001338 181.0
HFD2_k127_8616126_0 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 489.0
HFD2_k127_8616126_1 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007787 398.0
HFD2_k127_8616126_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000939 392.0
HFD2_k127_8616386_0 Heavy-metal-associated domain K01534 - 3.6.3.3,3.6.3.5 3.698e-237 756.0
HFD2_k127_8616386_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 509.0
HFD2_k127_8616386_10 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0002902 47.0
HFD2_k127_8616386_2 protein histidine kinase activity K03407,K07678 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002743 287.0
HFD2_k127_8616386_3 EamA-like transporter family - GO:0003333,GO:0003674,GO:0005215,GO:0005302,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015179,GO:0015192,GO:0015196,GO:0015238,GO:0015318,GO:0015711,GO:0015801,GO:0015807,GO:0015823,GO:0015827,GO:0015828,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000001426 229.0
HFD2_k127_8616386_4 Pfam:DUF422 - - - 0.000000000000000000000000000000000000000000000009 182.0
HFD2_k127_8616386_5 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000299 163.0
HFD2_k127_8616386_6 PFAM regulatory protein, ArsR K21903 - - 0.0000000000000000000000009596 107.0
HFD2_k127_8616386_7 cheY-homologous receiver domain K11443 - - 0.00000000000000002238 87.0
HFD2_k127_8616386_8 domain, Protein K09766 - - 0.000000000000008765 89.0
HFD2_k127_8616386_9 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000009722 66.0
HFD2_k127_8622014_0 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 460.0
HFD2_k127_8622014_1 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007632 456.0
HFD2_k127_8622014_2 nitrogen compound transport K00759,K02033 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 391.0
HFD2_k127_8622014_3 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008633 388.0
HFD2_k127_8622014_4 ABC-type dipeptide transport system periplasmic component K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006201 339.0
HFD2_k127_8622014_5 alpha-glucuronidase activity K01235 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010383,GO:0010410,GO:0010413,GO:0016052,GO:0016787,GO:0016798,GO:0033939,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044260,GO:0045491,GO:0045493,GO:0071554,GO:0071704,GO:1901575,GO:2000886 3.2.1.139 0.000000000000000000000000000000000000001829 153.0
HFD2_k127_8625397_0 PFAM galactose-1-phosphate uridyl transferase domain protein K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 491.0
HFD2_k127_8625397_1 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008504 339.0
HFD2_k127_8625397_2 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002348 259.0
HFD2_k127_8625397_3 TIGRFAM DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000955 193.0
HFD2_k127_8625397_4 - - - - 0.0000000000000000000000000003955 124.0
HFD2_k127_8625397_5 response regulator, receiver - - - 0.00000000000000000001163 103.0
HFD2_k127_8625397_6 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000005007 91.0
HFD2_k127_8625397_7 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000007812 83.0
HFD2_k127_8625397_8 Diguanylate cyclase - - - 0.000000003335 66.0
HFD2_k127_8626259_0 AI-2E family transporter K03548 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 347.0
HFD2_k127_8626259_1 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000543 285.0
HFD2_k127_8626259_2 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004827 246.0
HFD2_k127_8626259_3 Winged helix-turn helix - - - 0.000000000000000000000000000000000000000000000000000000001054 205.0
HFD2_k127_8626259_4 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000009 164.0
HFD2_k127_8626259_5 InterPro IPR009057 - - - 0.00000000000000000000000000000000000000005113 158.0
HFD2_k127_8626259_6 EamA-like transporter family - - - 0.000000000000000000000000000000000002143 141.0
HFD2_k127_8633161_0 transposition, DNA-mediated K02529,K20971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 338.0
HFD2_k127_8633161_1 Protein kinase domain - - - 0.000000000000000000000000000000000000000003729 157.0
HFD2_k127_8633161_2 transposition, DNA-mediated K02529,K20971 - - 0.00000000000000000000000000000000000156 151.0
HFD2_k127_8633161_3 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.00000000000000000000000005109 110.0
HFD2_k127_8633161_4 Protein of unknown function (DUF1566) - - - 0.000000000000000001847 94.0
HFD2_k127_8633161_5 transposition, DNA-mediated K02529,K20971 - - 0.000000000000000223 86.0
HFD2_k127_8653315_0 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003516 271.0
HFD2_k127_8653315_1 PFAM AMP-dependent synthetase and ligase K01897,K02182,K22319 - 6.1.3.1,6.2.1.3,6.2.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000001837 246.0
HFD2_k127_8653315_2 DNA-binding transcription factor activity K02470,K03833 - 5.99.1.3 0.000000000000000000000000000000000002759 153.0
HFD2_k127_8653315_3 - - - - 0.000000000000000000000000000000000009835 140.0
HFD2_k127_8653315_4 PFAM Cyclic nucleotide-binding K01420,K21563 - - 0.00000000000000000000001386 110.0
HFD2_k127_8653315_5 Belongs to the peptidase S8 family - - - 0.00000000000000000000002234 105.0
HFD2_k127_8653315_6 LysM domain - - - 0.00000000000000004989 94.0
HFD2_k127_8653315_7 LysM domain - - - 0.0000000000000542 83.0
HFD2_k127_866709_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 556.0
HFD2_k127_867725_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 8.977e-227 734.0
HFD2_k127_867725_1 Protein kinase; unclassified specificity. K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000139 181.0
HFD2_k127_867725_2 PFAM response regulator receiver K07667 - - 0.00000000000000000362 84.0
HFD2_k127_8691786_0 Stage II sporulation E family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 601.0
HFD2_k127_8691786_1 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 406.0
HFD2_k127_8691786_2 phosphorelay signal transduction system K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000009645 237.0
HFD2_k127_871002_0 Peptidase M14, carboxypeptidase A - - - 0.0 1307.0
HFD2_k127_8722606_0 metallopeptidase activity K21449 - - 0.00000000000000000000000000000000004728 156.0
HFD2_k127_8722606_1 PFAM Response regulator receiver domain K11624 - - 0.000000007852 57.0
HFD2_k127_8733841_0 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 291.0
HFD2_k127_8733841_1 Histidine kinase K07642 - 2.7.13.3 0.00000000000000000000000000000000000009324 146.0
HFD2_k127_8733841_2 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000001519 109.0
HFD2_k127_8733841_3 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000008016 106.0
HFD2_k127_8733841_4 PQQ-like domain - - - 0.000000000000000004367 97.0
HFD2_k127_8733841_5 WD40-like Beta Propeller Repeat - - - 0.00000000000000001941 96.0
HFD2_k127_8733841_6 peptidase C60 sortase A and B - - - 0.000000000003133 74.0
HFD2_k127_8733841_7 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000008766 63.0
HFD2_k127_8755071_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002823 284.0
HFD2_k127_8755071_1 TIGRFAM phosphate binding protein K02040 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000007181 128.0
HFD2_k127_8755071_2 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000000000000000000001422 108.0
HFD2_k127_8755071_3 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.0000000000001265 87.0
HFD2_k127_8755071_4 TIGRFAM phosphate binding protein K02040 - - 0.0000001224 65.0
HFD2_k127_8756817_0 Acetyltransferase (GNAT) domain - - - 0.000000000002174 74.0
HFD2_k127_8756817_1 Tetratricopeptide repeat - - - 0.0000003811 61.0
HFD2_k127_8757389_0 Putative metallopeptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 383.0
HFD2_k127_8757389_1 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 355.0
HFD2_k127_88102_0 AAA-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009962 636.0
HFD2_k127_88102_1 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 377.0
HFD2_k127_88102_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 351.0
HFD2_k127_88102_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000099 221.0
HFD2_k127_88102_4 lactoylglutathione lyase activity K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000008972 173.0
HFD2_k127_88102_5 DNA-binding transcription factor activity K03892 - - 0.00000000000000000000000000003067 119.0
HFD2_k127_88102_6 PFAM Pyridoxal-dependent decarboxylase conserved domain K01580,K01593,K13745 - 4.1.1.105,4.1.1.15,4.1.1.28,4.1.1.86 0.0000000000000000000002508 100.0
HFD2_k127_885989_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 4.578e-209 660.0
HFD2_k127_885989_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 525.0
HFD2_k127_885989_2 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K18917 - 1.20.4.3 0.0000000000000855 74.0
HFD2_k127_892265_0 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 493.0
HFD2_k127_892265_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 347.0
HFD2_k127_892265_2 Fungal trichothecene efflux pump (TRI12) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002895 290.0
HFD2_k127_892265_3 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000271 201.0
HFD2_k127_892265_4 Sucrose-6F-phosphate phosphohydrolase - - - 0.000000000000000000000000000284 124.0
HFD2_k127_892265_5 Protein of unknown function (DUF664) - - - 0.00000004716 54.0
HFD2_k127_895105_0 PFAM luciferase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 404.0
HFD2_k127_895105_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000001452 214.0
HFD2_k127_895105_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000002362 162.0
HFD2_k127_895105_3 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000003717 114.0
HFD2_k127_910508_0 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 493.0
HFD2_k127_910508_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 408.0
HFD2_k127_910508_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001547 284.0
HFD2_k127_910508_3 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000153 237.0
HFD2_k127_910508_4 Belongs to the FGGY kinase family K00880 - 2.7.1.53 0.000000000000000000000000000000000000000000000000000000001534 210.0
HFD2_k127_910508_5 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000003681 205.0
HFD2_k127_910508_6 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000002743 151.0
HFD2_k127_910508_7 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000001321 120.0
HFD2_k127_925421_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 423.0
HFD2_k127_925421_1 guanyl-nucleotide exchange factor activity K01183,K20276 GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009405,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944 3.2.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 334.0
HFD2_k127_925421_2 PFAM Uncharacterised BCR, COG1649 - - - 0.000000000000000000000000005136 127.0
HFD2_k127_925421_3 Pkd domain containing protein - - - 0.0000000000001018 85.0
HFD2_k127_929006_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 2.572e-237 748.0
HFD2_k127_929006_1 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 5.691e-214 675.0
HFD2_k127_929006_10 Iron-sulphur cluster assembly - - - 0.00000000496 60.0
HFD2_k127_929006_2 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 471.0
HFD2_k127_929006_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 413.0
HFD2_k127_929006_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009794 306.0
HFD2_k127_929006_5 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000002146 254.0
HFD2_k127_929006_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00338,K03615 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000002556 233.0
HFD2_k127_929006_7 Phosphoribosyl transferase domain K07101 - - 0.00000000000000000000000000000000000000000000000000000000000276 214.0
HFD2_k127_929006_8 Domain of unknown function (DUF892) - - - 0.000000000000000000000000000000000000000000000000000003068 195.0
HFD2_k127_929006_9 metallopeptidase activity - - - 0.00000000000000007194 91.0
HFD2_k127_9339_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.514e-239 756.0
HFD2_k127_9339_1 SMART serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 302.0
HFD2_k127_934769_0 OsmC-like protein K04063 - - 0.00000000000000000000000000000000000000000000000001184 183.0
HFD2_k127_934769_1 PFAM Class II aldolase adducin K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000006522 173.0
HFD2_k127_934769_2 PFAM response regulator receiver K02282 - - 0.0000000000000000000000000000000000000000871 166.0
HFD2_k127_934769_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000003798 153.0
HFD2_k127_934769_4 - K11477 - - 0.00000000000000000000000000000000003956 136.0
HFD2_k127_934769_5 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.000000000000000000000000000000001165 135.0
HFD2_k127_934769_6 Putative bacterial sensory transduction regulator - - - 0.0000000000001908 75.0
HFD2_k127_9354_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 321.0
HFD2_k127_9354_1 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000000000000000000000000000000000003002 190.0
HFD2_k127_9354_2 of nitrite reductase and ring-hydroxylating K05710 - - 0.0000000000000000000000000000002342 126.0
HFD2_k127_9354_3 Membrane - - - 0.00000000003187 77.0
HFD2_k127_9354_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0001655 55.0
HFD2_k127_948023_0 hydrolase, family 65, central catalytic K05342 - 2.4.1.64 4.065e-292 916.0
HFD2_k127_948023_1 COG1175 ABC-type sugar transport systems permease components K10233 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 313.0
HFD2_k127_948023_2 Sugar ABC transporter permease K10234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 314.0
HFD2_k127_949583_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 305.0
HFD2_k127_949583_1 Serine acetyltransferase, N-terminal K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000002516 162.0
HFD2_k127_949583_2 - - - - 0.000000000001847 69.0
HFD2_k127_949678_0 SMART Elongator protein 3 MiaB NifB - - - 1.012e-211 668.0
HFD2_k127_949678_1 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 423.0
HFD2_k127_949678_2 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000198 239.0
HFD2_k127_949678_3 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000232 203.0
HFD2_k127_949678_4 Polysaccharide biosynthesis protein - - - 0.0000001774 62.0
HFD2_k127_952001_0 Thermophilic metalloprotease (M29) K19689 - - 0.0000000000000000000000000000000000000000000000002384 181.0
HFD2_k127_952001_1 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000002114 177.0
HFD2_k127_952001_2 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000003318 130.0
HFD2_k127_952001_3 Protein of unknown function (DUF4013) - - - 0.00000000000001084 82.0
HFD2_k127_952001_4 Protein of unknown function (DUF4013) - - - 0.00000000000001751 82.0
HFD2_k127_952001_5 - - - - 0.0000000939 64.0
HFD2_k127_952285_0 POT family K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 505.0
HFD2_k127_952285_1 Metallopeptidase family M24 K01262 - 3.4.11.9 0.0000000000000000000000003699 113.0
HFD2_k127_96692_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.361e-294 917.0
HFD2_k127_96692_1 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 296.0
HFD2_k127_96692_2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.000000000000000000000000000000000000000000000000000000000000001552 235.0
HFD2_k127_96692_3 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000192 134.0
HFD2_k127_96692_4 - - - - 0.00000000000000000000003015 112.0
HFD2_k127_967420_0 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000007517 239.0
HFD2_k127_967420_1 photoreceptor activity K03303,K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000002771 190.0
HFD2_k127_967420_2 PFAM Binding-protein-dependent transport system inner membrane component K02025,K10241 - - 0.0000000000000000002436 90.0
HFD2_k127_967420_3 response regulator K07664 - - 0.00000000000000002198 87.0
HFD2_k127_967420_4 COG0642 Signal transduction histidine kinase - - - 0.00002824 51.0
HFD2_k127_972739_0 PFAM Rh family protein ammonium transporter K03320 - - 3.415e-226 711.0
HFD2_k127_972739_1 response regulator K07667 - - 0.000000000000000000000000000000000000000000001054 173.0
HFD2_k127_972739_2 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.0000000000000000000000000000002466 125.0
HFD2_k127_972739_3 PAS PAC sensor signal transduction histidine kinase K18350 - 2.7.13.3 0.0000000000000000000000000796 120.0
HFD2_k127_973586_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 537.0
HFD2_k127_973586_1 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 325.0
HFD2_k127_973586_2 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002457 282.0
HFD2_k127_973586_3 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000002469 272.0
HFD2_k127_973586_4 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000003971 244.0
HFD2_k127_973586_5 TIGRFAM thioredoxin K03671 - - 0.00000000000000000000000000000000000000000000915 173.0
HFD2_k127_973586_6 sh3 domain protein - - - 0.00000000000000000000000000000004594 141.0
HFD2_k127_973586_7 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000645 131.0
HFD2_k127_973586_8 Rhodanese Homology Domain - - - 0.000000000000004226 78.0
HFD2_k127_979406_0 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 314.0
HFD2_k127_979406_1 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000005714 180.0
HFD2_k127_979406_2 Acetyltransferase (GNAT) domain - - - 0.0000000000001108 72.0
HFD2_k127_988755_0 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 365.0
HFD2_k127_988755_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000001036 200.0
HFD2_k127_988755_2 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000001756 117.0
HFD2_k127_988755_3 Acetyltransferase (GNAT) family - - - 0.00001772 56.0
HFD2_k127_994185_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 473.0
HFD2_k127_994185_1 CpXC protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004078 265.0
HFD2_k127_994185_2 Bacterial protein of unknown function (DUF951) - - - 0.00000000000001338 74.0
HFD2_k127_994185_3 Putative diguanylate phosphodiesterase - - - 0.000000000001436 78.0
HFD2_k127_998465_0 OmpA family - - - 0.0 2113.0
HFD2_k127_998465_1 Domain of unknown function DUF11 - - - 0.0 1536.0
HFD2_k127_998465_2 Tetratricopeptide repeat - - - 2.39e-315 983.0
HFD2_k127_998465_3 Tetratricopeptide repeat - - - 2.344e-288 896.0
HFD2_k127_998465_4 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006846 546.0
HFD2_k127_998465_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003934 236.0
HFD2_k127_998465_6 response regulator K07720 - - 0.000000000000000000002821 97.0
HFD2_k127_998616_0 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 325.0
HFD2_k127_998616_1 B3/4 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 310.0
HFD2_k127_998616_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 296.0
HFD2_k127_998616_3 DNA photolyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000016 259.0
HFD2_k127_999044_0 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 436.0
HFD2_k127_999044_1 N-acetylglucosamine kinase activity K00884 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363 2.7.1.59 0.000000000000000000000000000000000000000000000000000002103 203.0
HFD2_k127_999044_2 PFAM Neutral alkaline nonlysosomal ceramidase - - - 0.000000000000000000000000000000000000000000000008119 187.0
HFD2_k127_999044_3 carbohydrate transport K02027 - - 0.00002119 49.0
HFD2_k127_999044_4 Creatininase - - - 0.00003435 52.0