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Overview

ID MAG01647
Name HFD2_bin.35
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Eisenbacteria
Class RBG-16-71-46
Order JABDJR01
Family JAWXBZ01
Genus
Species
Assembly information
Completeness (%) 80.57
Contamination (%) 1.41
GC content (%) 66.0
N50 (bp) 5,380
Genome size (bp) 3,927,238

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3270

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_1003690_0 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000244 190.0
HFD2_k127_1003690_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000282 181.0
HFD2_k127_100471_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009547 488.0
HFD2_k127_100471_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 316.0
HFD2_k127_100471_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 289.0
HFD2_k127_100471_3 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000001887 270.0
HFD2_k127_100471_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000002398 64.0
HFD2_k127_1013809_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 329.0
HFD2_k127_1013809_1 Putative neutral zinc metallopeptidase K06973 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004659 268.0
HFD2_k127_1013809_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.0000005909 54.0
HFD2_k127_1013809_3 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.0002839 44.0
HFD2_k127_1030467_0 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000003048 217.0
HFD2_k127_1030467_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000001829 147.0
HFD2_k127_1030467_2 Glycosyl transferase family 2 - - - 0.000000000000000000000001351 109.0
HFD2_k127_1048902_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007168 320.0
HFD2_k127_1048902_1 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000004055 252.0
HFD2_k127_1048902_2 Tetratricopeptide repeat - - - 0.0000000000000000002719 99.0
HFD2_k127_1048902_3 O-linked GlcNAc transferase-putative TPR-containing transmembrane protein - - - 0.0004893 51.0
HFD2_k127_1052262_0 Protein export membrane protein K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 359.0
HFD2_k127_1052262_1 SecD/SecF GG Motif K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005768 250.0
HFD2_k127_1057665_0 Non-ribosomal peptide synthetase modules and related - - - 1.017e-200 652.0
HFD2_k127_1057665_1 Amino acid adenylation domain - - - 0.0000000000392 66.0
HFD2_k127_1060904_0 Threonyl and Alanyl tRNA synthetase second additional domain K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 306.0
HFD2_k127_1060904_1 Belongs to the 5'-nucleotidase family K01081,K11751,K17224 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000002731 219.0
HFD2_k127_1060904_2 Belongs to the 5'-nucleotidase family K01081,K11751,K17224 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000001205 191.0
HFD2_k127_1060904_3 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.00000000000001018 87.0
HFD2_k127_1065411_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006846 436.0
HFD2_k127_1065411_1 methyltransferase activity - - - 0.000000000000000000000000000004547 125.0
HFD2_k127_1067018_0 PFAM ABC transporter K02056 - 3.6.3.17 2.653e-202 643.0
HFD2_k127_1067018_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 399.0
HFD2_k127_1067018_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 372.0
HFD2_k127_1067018_3 Protein of unknown function (DUF3798) - - - 0.00000000000000000000000000000000000000000000000000000000000000001835 229.0
HFD2_k127_1067018_4 HNH nucleases - - - 0.0000000000002508 75.0
HFD2_k127_1070591_0 PFAM DoxX family protein K15977 - - 0.0000000000000000000000000000000000007601 145.0
HFD2_k127_1070591_1 Cytochrome c - - - 0.000000000000000000000000000001013 125.0
HFD2_k127_1070591_2 - - - - 0.0000000000008466 82.0
HFD2_k127_1082948_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000001176 236.0
HFD2_k127_1084799_0 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 358.0
HFD2_k127_1084799_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000006956 232.0
HFD2_k127_1084799_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000223 178.0
HFD2_k127_1084799_3 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000000002118 93.0
HFD2_k127_1084799_4 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000001386 89.0
HFD2_k127_1084799_5 - - - - 0.00005146 53.0
HFD2_k127_108580_0 Glycosyltransferase like family 2 K03606,K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 356.0
HFD2_k127_108580_1 lipid kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004906 268.0
HFD2_k127_108580_2 PRC-barrel domain - - - 0.0000000000000000000000000000000002621 137.0
HFD2_k127_108580_3 phosphatidate phosphatase activity K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.000000000000000000000000002266 120.0
HFD2_k127_108580_4 BON domain - - - 0.00000000000000000007487 100.0
HFD2_k127_108580_5 Two component regulator propeller - - - 0.000000002456 70.0
HFD2_k127_1086345_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1060.0
HFD2_k127_1086345_1 Bacterial Ig-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 447.0
HFD2_k127_1086345_2 LVIVD repeat K01179 - 3.2.1.4 0.000000000001479 81.0
HFD2_k127_1098719_0 Protein of unknown function (DUF2723) - - - 0.0000000000000000002951 101.0
HFD2_k127_1098719_1 - - - - 0.000002193 56.0
HFD2_k127_1098719_2 Glycosyl transferase family 41 - - - 0.0004187 53.0
HFD2_k127_1127881_0 CHAT domain - - - 0.000000000000000000000000001018 128.0
HFD2_k127_1127881_1 DNA-templated transcription, initiation K03088 - - 0.00000000000000000007426 97.0
HFD2_k127_1127881_2 Putative zinc-finger - - - 0.00006409 54.0
HFD2_k127_1136926_0 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 426.0
HFD2_k127_1136926_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 333.0
HFD2_k127_1139688_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008569 495.0
HFD2_k127_1139688_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 309.0
HFD2_k127_1139688_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000001561 205.0
HFD2_k127_1139688_3 ABC-type uncharacterized transport system K01992 - - 0.000000000000000000000002891 117.0
HFD2_k127_1139758_0 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000001914 209.0
HFD2_k127_1139758_2 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000003622 87.0
HFD2_k127_1143332_0 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001146 293.0
HFD2_k127_1143332_1 PFAM Glycosyltransferase family 28 C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006908 263.0
HFD2_k127_1143332_2 Glycosyltransferase Family 4 - - - 0.0001006 46.0
HFD2_k127_1144220_0 Domain of unknown function (DUF4070) - - - 1.588e-205 651.0
HFD2_k127_1144220_1 DNA polymerase type-B family K02336 - 2.7.7.7 6.838e-198 643.0
HFD2_k127_1144220_2 COG1045 Serine acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 325.0
HFD2_k127_1144220_3 PFAM polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000001235 140.0
HFD2_k127_1144220_4 glycosyl transferase group 1 - - - 0.0000000000000000000000000001722 133.0
HFD2_k127_1144220_5 Peptidase dimerisation domain K01436,K12940 - - 0.0000000003452 63.0
HFD2_k127_1145835_0 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008879 417.0
HFD2_k127_1145835_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007073 422.0
HFD2_k127_1160087_0 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000005627 240.0
HFD2_k127_1160087_1 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000007273 133.0
HFD2_k127_1162554_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000001505 144.0
HFD2_k127_1165518_0 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008690,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0046401,GO:0046872,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.38 0.0000000000000000000000000000000000000000000008073 173.0
HFD2_k127_1165518_1 - - - - 0.0000000000000000000000001762 116.0
HFD2_k127_1182976_0 Poly A polymerase head domain K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 325.0
HFD2_k127_1182976_1 Protein conserved in bacteria K09931 - - 0.00000000000000000000000000000000000006127 150.0
HFD2_k127_1182976_2 Pkd domain containing protein - - - 0.000000000000000000000000000000000009445 153.0
HFD2_k127_1182976_3 cellulase activity - - - 0.0004217 53.0
HFD2_k127_1184880_0 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 3.261e-201 655.0
HFD2_k127_1184880_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 490.0
HFD2_k127_1184880_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000001689 180.0
HFD2_k127_1184880_3 DoxX K15977 - - 0.0000000000000000000000000001101 124.0
HFD2_k127_1184880_4 Tetratricopeptide repeat - - - 0.000000001272 67.0
HFD2_k127_1185949_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 322.0
HFD2_k127_1185949_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002021 280.0
HFD2_k127_1185949_2 Deoxynucleoside kinase K15518 - 2.7.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000001198 249.0
HFD2_k127_1185949_3 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000001458 224.0
HFD2_k127_1185949_4 PFAM histidine triad (HIT) protein K19710 - 2.7.7.53 0.00000000000000000000000000000000000000004464 167.0
HFD2_k127_1185949_5 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000000000000264 157.0
HFD2_k127_1185949_6 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000001633 98.0
HFD2_k127_1192276_0 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008287 376.0
HFD2_k127_1192276_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001711 273.0
HFD2_k127_1192276_2 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000000000000000000000000003491 217.0
HFD2_k127_1192276_3 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000002676 196.0
HFD2_k127_1195813_0 PFAM Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 399.0
HFD2_k127_1195813_1 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.0000000000000000000000000000000000000000000000009825 177.0
HFD2_k127_1196734_0 MutL protein K00854 - 2.7.1.17 9.757e-255 799.0
HFD2_k127_1196734_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 610.0
HFD2_k127_1196734_10 - - - - 0.00008862 53.0
HFD2_k127_1196734_2 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008433 395.0
HFD2_k127_1196734_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 347.0
HFD2_k127_1196734_4 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 340.0
HFD2_k127_1196734_5 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006865 283.0
HFD2_k127_1196734_6 - - - - 0.00000000000000000000000000000000000000000000000000000002194 203.0
HFD2_k127_1196734_7 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000000000000000000000000000000001005 206.0
HFD2_k127_1196734_8 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation K03800 - 6.3.1.20 0.00000000000000000000000000007569 123.0
HFD2_k127_1196734_9 - - - - 0.0000000000000001782 86.0
HFD2_k127_1200579_0 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000001365 165.0
HFD2_k127_1200579_1 Capsular exopolysaccharide family - - - 0.0000000000000000000002672 107.0
HFD2_k127_1200579_2 polysaccharide export protein K01991 - - 0.0000000000000000000005629 107.0
HFD2_k127_1200579_3 chain length determinant protein - - - 0.000004334 59.0
HFD2_k127_1204353_0 cellulose binding - - - 3.425e-214 719.0
HFD2_k127_1204353_1 Cytochrome c - - - 1.645e-197 627.0
HFD2_k127_1204353_2 - - - - 0.000000000000000000000002025 115.0
HFD2_k127_1204353_3 LVIVD repeat - - - 0.000000000000000002029 101.0
HFD2_k127_1204353_4 PQQ enzyme repeat - - - 0.0000000000000008417 91.0
HFD2_k127_1204353_5 - - - - 0.00000001863 67.0
HFD2_k127_1208877_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000002084 143.0
HFD2_k127_1208877_1 Yip1 domain - - - 0.00000000000002158 83.0
HFD2_k127_1208877_2 Amidohydrolase family - - - 0.000000000007295 71.0
HFD2_k127_1208877_3 phosphorelay signal transduction system K02481 - - 0.000000007847 58.0
HFD2_k127_1208877_4 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000004992 58.0
HFD2_k127_1211530_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 452.0
HFD2_k127_1211530_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 329.0
HFD2_k127_1211530_3 Acetyltransferase (GNAT) domain - - - 0.000000000005956 71.0
HFD2_k127_123003_0 platelet-activating factor acetyltransferase activity - - - 0.00001097 57.0
HFD2_k127_123003_1 Peroxisome biogenesis protein K13342 GO:0000268,GO:0003674,GO:0005048,GO:0005052,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005778,GO:0005829,GO:0006605,GO:0006625,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0009719,GO:0009725,GO:0009733,GO:0009987,GO:0010033,GO:0015031,GO:0015833,GO:0015919,GO:0016020,GO:0016043,GO:0016558,GO:0016560,GO:0017038,GO:0031090,GO:0031903,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042221,GO:0042277,GO:0042579,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043574,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0044743,GO:0045184,GO:0046907,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:0098588,GO:0098805 - 0.0009907 51.0
HFD2_k127_1254142_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 1.177e-306 953.0
HFD2_k127_1254142_1 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007851 281.0
HFD2_k127_1254142_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000001758 209.0
HFD2_k127_1254142_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000006415 199.0
HFD2_k127_1254142_4 G/U mismatch-specific uracil-DNA glycosylase activity K20813 - 3.2.2.29 0.00000000000000000000000000000000000000000004883 166.0
HFD2_k127_1254142_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000006889 81.0
HFD2_k127_1254142_6 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00000000002787 76.0
HFD2_k127_1254142_7 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0001634 54.0
HFD2_k127_1263692_0 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000864 409.0
HFD2_k127_1263692_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000003047 158.0
HFD2_k127_1263692_2 PFAM Carbamoyltransferase K00612 - - 0.0000000000000000000000000000002269 124.0
HFD2_k127_1267790_0 adenosylhomocysteinase activity K01251 - 3.3.1.1 1.784e-196 621.0
HFD2_k127_1267790_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 456.0
HFD2_k127_1267790_10 adenosine deaminase K01488,K21053 - 3.5.4.2,3.5.4.4 0.0000272 48.0
HFD2_k127_1267790_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0004470,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008062 377.0
HFD2_k127_1267790_3 Ribonuclease E/G family K08301 - - 0.000000000000000000000000000000000000000000000000000000000000001799 224.0
HFD2_k127_1267790_4 lyase activity K01387,K03301 - 3.4.24.3 0.00000000000000000000000000000000000000000000000000001142 215.0
HFD2_k127_1267790_5 Bacterial membrane protein YfhO - - - 0.00000000000000000000000000000000000001334 167.0
HFD2_k127_1267790_6 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000001268 151.0
HFD2_k127_1267790_7 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000007501 126.0
HFD2_k127_1267790_8 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000006051 78.0
HFD2_k127_1267790_9 PFAM regulatory protein ArsR - - - 0.0000000003245 65.0
HFD2_k127_1272789_0 SERine Proteinase INhibitors K13963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 377.0
HFD2_k127_1272789_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000007634 222.0
HFD2_k127_1274654_0 Nitrate reductase alpha subunit K17050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 377.0
HFD2_k127_1274654_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 318.0
HFD2_k127_128064_0 nitrite transmembrane transporter activity - - - 0.0 1069.0
HFD2_k127_128064_1 ERAP1-like C-terminal domain K01256,K01263 - 3.4.11.14,3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007603 516.0
HFD2_k127_128064_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.00000000000000000000000000000000000000000000000000000000000000000000252 239.0
HFD2_k127_128064_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000001129 190.0
HFD2_k127_128064_4 Bacterial regulatory proteins, crp family K10914 - - 0.00000000000000000000000000000000000000000000006125 183.0
HFD2_k127_1285652_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001054 278.0
HFD2_k127_1286397_0 Iron-containing alcohol dehydrogenase K00001,K13954 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001851 264.0
HFD2_k127_1286397_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000002796 255.0
HFD2_k127_1296479_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001026 276.0
HFD2_k127_1296479_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000001203 153.0
HFD2_k127_1296479_2 O-linked n-acetylglucosamine transferase - - - 0.0000000000000000000000008289 111.0
HFD2_k127_1307110_0 Belongs to the peptidase S8 family K01280 - 3.4.14.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 337.0
HFD2_k127_1307110_1 YCII-related domain - - - 0.000000000000000000000000000000000000154 145.0
HFD2_k127_1307110_2 Protein of unknown function (DUF423) - - - 0.00000000000000000000000000000000001438 138.0
HFD2_k127_1307110_3 Chalcone isomerase-like - - - 0.0004374 52.0
HFD2_k127_1309219_0 Alginate export K16081 - - 0.0000000000000000000000000000000000000008588 165.0
HFD2_k127_1309219_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147 - - 0.00000000000000000000003405 110.0
HFD2_k127_1309219_2 cellulose binding - - - 0.0000000006271 72.0
HFD2_k127_1309219_3 extracellular matrix structural constituent - - - 0.000003688 59.0
HFD2_k127_1311798_0 Type II and III secretion system protein K02666 - - 0.00000000000000000000000000000000000000002644 172.0
HFD2_k127_1311798_1 Pilus assembly protein, PilO K02664 - - 0.0000000000000000001662 98.0
HFD2_k127_1311798_2 PFAM Fimbrial assembly family protein K02663 - - 0.000000006403 64.0
HFD2_k127_1311798_3 Pilus assembly protein, PilP K02665 - - 0.0000413 53.0
HFD2_k127_1319041_0 Glycosyl transferase 4-like K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 376.0
HFD2_k127_1319041_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009752 359.0
HFD2_k127_1319041_2 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000001302 145.0
HFD2_k127_1319041_3 N-acetylglucosaminylinositol deacetylase activity K01463 - - 0.00000000000008987 74.0
HFD2_k127_1331533_0 GMC oxidoreductase - - - 4.946e-216 688.0
HFD2_k127_1331533_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 345.0
HFD2_k127_1331533_2 Major intrinsic protein K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005214 271.0
HFD2_k127_1331533_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000000004545 226.0
HFD2_k127_1331533_4 - - - - 0.0000000000000000000000000000000000000000000000000000116 199.0
HFD2_k127_1331533_5 Amylo-alpha-1,6-glucosidase - - - 0.000000000000003401 75.0
HFD2_k127_1334997_0 TIGRFAM type VI secretion protein, EvpB VC_A0108 family - - - 0.0000000000000000000000000005543 132.0
HFD2_k127_1334997_1 Uncharacterized protein conserved in bacteria (DUF2094) K11890,K11910 - - 0.000000000004567 77.0
HFD2_k127_1334997_2 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11901 - - 0.000047 50.0
HFD2_k127_1342296_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 541.0
HFD2_k127_1342296_1 Cystathionine beta-synthase K01697 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 477.0
HFD2_k127_1342296_2 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000002215 106.0
HFD2_k127_1348020_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 410.0
HFD2_k127_1348020_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 333.0
HFD2_k127_1348020_2 major pilin protein fima - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007827 289.0
HFD2_k127_1350360_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 471.0
HFD2_k127_1350360_1 8-amino-7-oxononanoate synthase activity K00639,K00652 - 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009002 403.0
HFD2_k127_1350360_2 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 315.0
HFD2_k127_1350360_3 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000003138 234.0
HFD2_k127_1372955_0 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009991 418.0
HFD2_k127_1372955_1 LemA family K03744 - - 0.000000000000000000000000000000000000000002949 167.0
HFD2_k127_1372955_2 E3 Ubiquitin ligase - - - 0.000000000003758 79.0
HFD2_k127_1372955_3 cyclic nucleotide-binding K01420 - - 0.000000001558 68.0
HFD2_k127_1375043_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008018 259.0
HFD2_k127_1375043_1 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002133 250.0
HFD2_k127_1375043_2 membrane - - - 0.0000000000000000000000000000000000000000001056 169.0
HFD2_k127_1375043_3 Cell wall-active antibiotics response 4TMS YvqF - - - 0.00000000000000005932 85.0
HFD2_k127_1375043_4 Polysaccharide biosynthesis protein - - - 0.0002835 49.0
HFD2_k127_137821_0 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001223 272.0
HFD2_k127_137821_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000001721 246.0
HFD2_k127_1380653_1 PPIC-type PPIASE domain K03769,K07533 - 5.2.1.8 0.00000000000000000000000000000000001564 154.0
HFD2_k127_1380653_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000038 122.0
HFD2_k127_1380653_3 Bacteriochlorophyll chlorophyll K04040 - 2.5.1.133,2.5.1.62 0.00000000000000000002113 100.0
HFD2_k127_1391767_0 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 346.0
HFD2_k127_1391767_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000001628 270.0
HFD2_k127_1391767_2 cytochrome oxidase assembly K02259 - - 0.00000000000000000000000000002706 126.0
HFD2_k127_1391767_3 Transport permease protein K01992 - - 0.00005135 49.0
HFD2_k127_139338_0 PFAM cytochrome c, class I - - - 0.0000000000000000000000000000000000000000000000000000000000006543 222.0
HFD2_k127_139338_1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase - - - 0.0000000000000000000000000000000000000002217 150.0
HFD2_k127_139338_2 Acetyltransferase (GNAT) domain - - - 0.000000000000006073 84.0
HFD2_k127_139338_3 Cytochrome oxidase complex assembly protein 1 - - - 0.0000000000009113 76.0
HFD2_k127_1395007_0 Multicopper oxidase K22350 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 609.0
HFD2_k127_1395007_1 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000001293 183.0
HFD2_k127_1403205_0 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000786 393.0
HFD2_k127_1403205_1 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 387.0
HFD2_k127_1403205_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 384.0
HFD2_k127_1406564_0 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008844 505.0
HFD2_k127_1406564_1 Amino acid kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005126 330.0
HFD2_k127_1406564_2 Fn3 associated - - - 0.0001582 52.0
HFD2_k127_1407029_0 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000911 228.0
HFD2_k127_1407029_1 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000234 214.0
HFD2_k127_1407029_2 PFAM Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000000000000000000004444 162.0
HFD2_k127_1408552_0 amino acid activation for nonribosomal peptide biosynthetic process K17713,K20952 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 401.0
HFD2_k127_1408552_1 Peptidase family C25 - - - 0.0000000000000000000000000000000000001686 161.0
HFD2_k127_1408552_2 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000002806 87.0
HFD2_k127_1438020_0 lysine biosynthetic process via aminoadipic acid - - - 1.721e-218 699.0
HFD2_k127_1440811_0 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall - - - 0.0 1106.0
HFD2_k127_145794_0 Evidence 5 No homology to any previously reported sequences K17713 - - 0.0000000000000000000000000000000000000000000000000000000000000000001189 262.0
HFD2_k127_1459495_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 383.0
HFD2_k127_1459495_1 C-terminal domain of CHU protein family - - - 0.0000008526 62.0
HFD2_k127_1459495_2 long-chain fatty acid transport protein - - - 0.00009984 53.0
HFD2_k127_1461765_0 transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 436.0
HFD2_k127_1461765_1 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000003794 248.0
HFD2_k127_1461765_2 Domain of Unknown Function (DUF1206) - - - 0.0000000000000000000000002844 113.0
HFD2_k127_1461765_3 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000003086 90.0
HFD2_k127_1470303_0 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 431.0
HFD2_k127_1470303_2 COG0457 FOG TPR repeat - - - 0.0000000000005568 83.0
HFD2_k127_1473728_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007541 467.0
HFD2_k127_1473728_1 Histidine kinase K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000005337 268.0
HFD2_k127_1473728_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000003075 207.0
HFD2_k127_147442_0 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 389.0
HFD2_k127_147442_1 Signal transduction histidine kinase K07710 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000003263 198.0
HFD2_k127_147442_2 bacterial-type flagellum-dependent cell motility - - - 0.0000000000628 74.0
HFD2_k127_1486107_0 sister chromatid segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 310.0
HFD2_k127_1491218_0 6-phosphogluconolactonase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 552.0
HFD2_k127_1491218_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759,K05606 - 4.4.1.5,5.1.99.1 0.000000000000000000000000000000000000000001112 162.0
HFD2_k127_1491218_2 LVIVD repeat K01179 - 3.2.1.4 0.0000000001448 75.0
HFD2_k127_1491218_3 translation initiation factor activity - - - 0.000000001421 70.0
HFD2_k127_1494631_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 361.0
HFD2_k127_1494631_1 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000008189 249.0
HFD2_k127_1494631_2 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000005331 230.0
HFD2_k127_1494631_3 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760,K04075,K15780 GO:0003674,GO:0003824,GO:0004422,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0052657,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.8,6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000001717 220.0
HFD2_k127_1494631_4 - - - - 0.000000000000000000000000000000000000000139 172.0
HFD2_k127_1494631_5 Lamin Tail Domain K07004 - - 0.000000000000000000000000517 118.0
HFD2_k127_1494631_6 Belongs to the peptidase S8 family - - - 0.00000000000000002289 97.0
HFD2_k127_1494631_7 Ethanolamine utilisation protein EutN/carboxysome K04028 - - 0.00000000000008347 78.0
HFD2_k127_1494631_8 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0000000000001084 72.0
HFD2_k127_1506638_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 599.0
HFD2_k127_1506638_1 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 338.0
HFD2_k127_1506638_2 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000006698 186.0
HFD2_k127_1506638_3 SnoaL-like domain - - - 0.0000000004135 69.0
HFD2_k127_1561756_0 Anticodon-binding domain of tRNA K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 526.0
HFD2_k127_1561756_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000001056 211.0
HFD2_k127_1561759_0 PD-(D/E)XK nuclease superfamily - - - 0.0000000002615 74.0
HFD2_k127_1571300_0 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 365.0
HFD2_k127_1571300_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005897 346.0
HFD2_k127_1571300_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000003853 111.0
HFD2_k127_1571300_3 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000002606 56.0
HFD2_k127_1579262_0 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 572.0
HFD2_k127_1579262_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 520.0
HFD2_k127_1579262_2 ROK family K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 406.0
HFD2_k127_1579262_3 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 363.0
HFD2_k127_1579262_4 converts alpha-aldose to the beta-anomer - - - 0.000000000000000000000000000000000000000000000007702 194.0
HFD2_k127_1579262_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000004924 118.0
HFD2_k127_1579262_6 acyl carrier protein - - - 0.000000000000000000000007601 102.0
HFD2_k127_1579262_7 - - - - 0.00000000000000000005475 92.0
HFD2_k127_1579262_8 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end - - - 0.00000004858 66.0
HFD2_k127_1590105_0 SpoIVB peptidase S55 K00973,K02414,K21449 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000003012 266.0
HFD2_k127_1590105_1 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007864 258.0
HFD2_k127_1590105_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000001075 75.0
HFD2_k127_1630839_0 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002794 243.0
HFD2_k127_1630839_1 cellulase activity - - - 0.00008539 53.0
HFD2_k127_1635861_0 Multidrug ABC transporter ATP-binding protein K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 482.0
HFD2_k127_1635861_1 aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 332.0
HFD2_k127_1635861_2 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 301.0
HFD2_k127_1635861_3 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000648 291.0
HFD2_k127_1652700_0 Spore coat protein CotH K01216,K07004 - 3.2.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 502.0
HFD2_k127_1652700_1 response to antibiotic - - - 0.00000000000000000000002686 117.0
HFD2_k127_1657110_0 4Fe-4S dicluster domain K00184 - - 0.0 1043.0
HFD2_k127_1657110_1 Polysulphide reductase, NrfD K00185 - - 1.312e-205 672.0
HFD2_k127_1657110_2 Cytochrome c7 and related cytochrome c K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 306.0
HFD2_k127_1657110_3 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004384 244.0
HFD2_k127_1657110_4 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000000000000001721 198.0
HFD2_k127_1657110_5 Alpha beta hydrolase fold - - - 0.000000000000000000000000000000000003676 149.0
HFD2_k127_1657110_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000003429 78.0
HFD2_k127_1657110_7 - - - - 0.00000001641 62.0
HFD2_k127_1662041_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840,K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 501.0
HFD2_k127_1662041_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 395.0
HFD2_k127_1662041_2 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 359.0
HFD2_k127_1662041_3 Methylpurine-DNA glycosylase (MPG) K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000000001348 181.0
HFD2_k127_1662041_4 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000008711 136.0
HFD2_k127_1662041_5 - - - - 0.000000004255 68.0
HFD2_k127_1662041_6 Ethylbenzene dehydrogenase - - - 0.0001592 54.0
HFD2_k127_1668464_0 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005274 567.0
HFD2_k127_1668464_1 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000759 292.0
HFD2_k127_1668464_2 Inositol monophosphatase K01082,K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000002675 252.0
HFD2_k127_1677124_0 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 460.0
HFD2_k127_1677124_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000004971 210.0
HFD2_k127_1680315_0 Oxidoreductase NAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000003175 222.0
HFD2_k127_1680315_1 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000001747 112.0
HFD2_k127_1691355_0 cellulose binding - - - 0.0000000000000000000006639 113.0
HFD2_k127_1691355_1 Histidine triad (Hit) protein K02503 - - 0.0000000000000000003437 88.0
HFD2_k127_1691355_2 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000005421 87.0
HFD2_k127_1691355_3 FlgD Ig-like domain - - - 0.00000000000007143 86.0
HFD2_k127_1691355_4 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000002837 84.0
HFD2_k127_1701005_0 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 326.0
HFD2_k127_1701005_1 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000009031 184.0
HFD2_k127_1701005_2 - - - - 0.000000000000000000000000003056 119.0
HFD2_k127_1701005_3 SMART regulatory protein ArsR - - - 0.000000000000002318 80.0
HFD2_k127_1701005_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000737 48.0
HFD2_k127_1710954_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 346.0
HFD2_k127_1710954_1 Protein of unknown function (DUF2723) K16928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 309.0
HFD2_k127_1710954_2 xylanase chitin deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008373 288.0
HFD2_k127_1710954_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000009092 220.0
HFD2_k127_1710954_4 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000000000000000000000000002022 199.0
HFD2_k127_1710954_5 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000001242 112.0
HFD2_k127_1710954_6 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000002394 105.0
HFD2_k127_1710954_7 Protein of unknown function (DUF3485) - - - 0.0000000000000000000009291 110.0
HFD2_k127_1716014_0 GTP-binding protein TypA K06207 - - 3.346e-261 817.0
HFD2_k127_1716014_1 acyl-CoA dehydrogenase activity K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 528.0
HFD2_k127_1716014_2 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000008802 233.0
HFD2_k127_1716014_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000002757 215.0
HFD2_k127_1716014_4 5'-nucleotidase - - - 0.00000000000000000000000000000001356 141.0
HFD2_k127_1718557_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K18307 - - 0.0 1093.0
HFD2_k127_1718557_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 392.0
HFD2_k127_1718557_2 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007092 376.0
HFD2_k127_1718557_3 PFAM peptidase M14 carboxypeptidase A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004724 269.0
HFD2_k127_1718991_0 Type VI secretion protein, EvpB/VC_A0108, tail sheath K11900 - - 1.685e-232 727.0
HFD2_k127_1718991_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000003794 250.0
HFD2_k127_1718991_2 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ K11910 - - 0.00000000000000000000000000000000000000000000000000000000000000001949 243.0
HFD2_k127_1718991_3 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11901 - - 0.0000000000000000000000000000000000000000000000000000000007637 208.0
HFD2_k127_1718991_4 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000001194 204.0
HFD2_k127_1722899_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.747e-201 647.0
HFD2_k127_1722899_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 312.0
HFD2_k127_1722899_2 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000007904 109.0
HFD2_k127_1731285_0 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 1.494e-227 717.0
HFD2_k127_1731285_1 Surface antigen K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.000000000000000000000000000000005503 145.0
HFD2_k127_1741379_0 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 376.0
HFD2_k127_1746251_0 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 361.0
HFD2_k127_1746251_1 TIGRFAM Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000001989 242.0
HFD2_k127_1746251_2 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000001568 126.0
HFD2_k127_1746251_3 - - - - 0.00000001733 60.0
HFD2_k127_1749729_0 translation release factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 362.0
HFD2_k127_1749729_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000007742 243.0
HFD2_k127_1749729_2 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000001679 175.0
HFD2_k127_1749729_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000001488 162.0
HFD2_k127_1749729_4 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000005651 138.0
HFD2_k127_1749729_5 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.0000000000000000005318 102.0
HFD2_k127_1749729_6 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.0000002229 63.0
HFD2_k127_1755713_0 Methylenetetrahydrofolate reductase K00297,K00547,K00548 - 1.5.1.20,2.1.1.10,2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 612.0
HFD2_k127_1755713_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 304.0
HFD2_k127_1755713_2 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 313.0
HFD2_k127_1755713_3 Cytochrome C assembly protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000004922 209.0
HFD2_k127_1755713_4 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.00000000000000000000000000000000000000000000000000000002586 204.0
HFD2_k127_1755713_5 CcmB protein K02193,K02194 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 0.0000000000000000000000000000000000000000000000000001395 194.0
HFD2_k127_1755713_6 Abc transporter K01990 - - 0.00000000000000000000000000000000000000000002136 171.0
HFD2_k127_1755713_7 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000003216 117.0
HFD2_k127_1755713_8 PFAM Colicin V production K03558 - - 0.0000000000000741 78.0
HFD2_k127_1761393_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008458 416.0
HFD2_k127_1761393_1 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000001447 112.0
HFD2_k127_1780362_0 polysaccharide biosynthetic process K16712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 299.0
HFD2_k127_1780362_1 Teichuronic acid biosynthesis glycosyltransferase tuaH - - - 0.00000000000000000000000000000000000001128 159.0
HFD2_k127_1793698_0 ATP ADP translocase K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 329.0
HFD2_k127_1793698_2 GAF domain-containing protein K08968 - 1.8.4.14 0.000000000000000000000000000003086 123.0
HFD2_k127_1802730_0 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006547 453.0
HFD2_k127_1802730_1 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 368.0
HFD2_k127_1825570_0 1,4-alpha-glucan branching enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 555.0
HFD2_k127_1825570_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005321 404.0
HFD2_k127_1825570_10 methyltransferase activity - - - 0.0000000001545 68.0
HFD2_k127_1825570_11 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000003016 61.0
HFD2_k127_1825570_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007878 312.0
HFD2_k127_1825570_3 Conserved TM helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 317.0
HFD2_k127_1825570_4 Activator of Hsp90 ATPase 1 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008488 253.0
HFD2_k127_1825570_5 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000009823 238.0
HFD2_k127_1825570_6 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000001979 253.0
HFD2_k127_1825570_7 Protein of unknown function (DUF3455) - - - 0.00000000000000000000003905 106.0
HFD2_k127_1825570_8 - - - - 0.00000000000000002917 83.0
HFD2_k127_1825570_9 - - - - 0.000000000000001844 83.0
HFD2_k127_1845252_0 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 342.0
HFD2_k127_1845252_1 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 315.0
HFD2_k127_1845252_2 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 308.0
HFD2_k127_1845252_3 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000001829 251.0
HFD2_k127_1845252_4 Pentapeptide repeats (9 copies) - - - 0.0000000000000000000000001898 117.0
HFD2_k127_1846424_0 TIGRFAM Dihydroorotate dehydrogenase K17723 - 1.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 587.0
HFD2_k127_185433_0 Pyridoxal-phosphate dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 408.0
HFD2_k127_185433_1 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000003071 157.0
HFD2_k127_185703_0 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.00000000000000000000000000000000000000000000000000000001446 206.0
HFD2_k127_185703_1 RNA methylase K07444 - - 0.000000000000000000000000000000000000000000000146 177.0
HFD2_k127_185703_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000001743 114.0
HFD2_k127_1875380_0 Peptidase S8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 398.0
HFD2_k127_1875380_2 Pregnancy-associated plasma protein-A - - - 0.000000000000000000000000000000000009058 158.0
HFD2_k127_1875380_3 - - - - 0.00000000000000002462 89.0
HFD2_k127_1875380_4 extracellular matrix structural constituent - - - 0.0000000000000001006 95.0
HFD2_k127_1875380_5 Peptidoglycan-binding domain 1 protein K07260 - 3.4.17.14 0.000000000000001058 87.0
HFD2_k127_1878733_0 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 583.0
HFD2_k127_1878733_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000000000000000000000000000000004353 246.0
HFD2_k127_1878733_3 LVIVD repeat K01179 - 3.2.1.4 0.0003514 53.0
HFD2_k127_1887159_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000003615 152.0
HFD2_k127_1887159_1 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000000000005685 138.0
HFD2_k127_1887159_2 Subtilase family - - - 0.00001639 58.0
HFD2_k127_1895539_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 4.809e-196 656.0
HFD2_k127_1895539_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 428.0
HFD2_k127_1895539_10 SnoaL-like domain - - - 0.00000000000003236 77.0
HFD2_k127_1895539_11 Putative bacterial lipoprotein (DUF799) - - - 0.0000000007282 68.0
HFD2_k127_1895539_12 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000001859 66.0
HFD2_k127_1895539_2 His Kinase A (phosphoacceptor) domain K00694,K03406,K07315,K14986 - 2.4.1.12,2.7.13.3,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 387.0
HFD2_k127_1895539_3 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 375.0
HFD2_k127_1895539_4 Rubrerythrin K22336 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000009648 205.0
HFD2_k127_1895539_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000646 183.0
HFD2_k127_1895539_6 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000003924 172.0
HFD2_k127_1895539_7 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.000000000000000000000000007606 115.0
HFD2_k127_1895539_8 6-bladed beta-propeller - - - 0.00000000000000004269 93.0
HFD2_k127_1895539_9 curli production assembly transport component CsgG - - - 0.00000000000000156 91.0
HFD2_k127_1895833_0 Multicopper oxidase K06324 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 360.0
HFD2_k127_1895833_1 Belongs to the 'phage' integrase family - - - 0.00001271 50.0
HFD2_k127_1921615_0 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 5.783e-224 715.0
HFD2_k127_1921615_1 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 429.0
HFD2_k127_1921615_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000001003 215.0
HFD2_k127_1921615_3 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000298 158.0
HFD2_k127_1921615_4 nickel cation binding K04651 - - 0.0000000000000000000000001115 116.0
HFD2_k127_1923625_0 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000007062 91.0
HFD2_k127_1930116_0 PA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 462.0
HFD2_k127_1930116_1 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 354.0
HFD2_k127_1930116_2 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000001403 137.0
HFD2_k127_1930116_3 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000849 116.0
HFD2_k127_1930116_4 Dodecin K09165 - - 0.000000000000000000004734 107.0
HFD2_k127_1930116_5 - - - - 0.00002014 52.0
HFD2_k127_1959563_0 membrane - - - 0.0000000006253 72.0
HFD2_k127_1976530_0 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000008687 183.0
HFD2_k127_1976530_1 Peptidase family C25 - - - 0.0000000000000000000000000000883 128.0
HFD2_k127_1983160_0 Protein of unknown function (DUF2723) K16928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 348.0
HFD2_k127_1983160_1 Protein of unknown function (DUF2723) - - - 0.0000000000000000000000000000000000000000000000001436 190.0
HFD2_k127_199402_0 Involved in the biosynthesis of porphyrin-containing compound K02495 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 358.0
HFD2_k127_199402_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000592 337.0
HFD2_k127_199402_2 imidazolonepropionase activity - - - 0.000000000000000000000000000000000000000000000000000000000001925 219.0
HFD2_k127_2015037_0 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 443.0
HFD2_k127_2015037_1 Transcriptional regulator K03717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 350.0
HFD2_k127_2015037_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 325.0
HFD2_k127_2015037_3 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00239 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000001013 235.0
HFD2_k127_2026593_0 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006285 323.0
HFD2_k127_2026593_1 Cobyrinic acid ac-diamide synthase K03496 GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 311.0
HFD2_k127_2026593_2 Belongs to the ParB family K03497 GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000143 246.0
HFD2_k127_2026593_3 Polymer-forming cytoskeletal - - - 0.00000000000000002282 87.0
HFD2_k127_2032303_0 ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001165 259.0
HFD2_k127_2032303_1 ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - 0.00000000000000000000000000000000000000000000000007203 187.0
HFD2_k127_2032303_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000125 148.0
HFD2_k127_2032303_3 Tetratricopeptide repeat - - - 0.00000000000000261 87.0
HFD2_k127_2032303_4 Type IV pilin PilA K02650 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.00000000005068 69.0
HFD2_k127_2036453_0 Glycosyltransferase like family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009202 303.0
HFD2_k127_2036453_1 PFAM Polysaccharide deacetylase - - - 0.00000000000000000004788 102.0
HFD2_k127_2036453_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000001041 60.0
HFD2_k127_2036453_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0001994 54.0
HFD2_k127_2058707_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000003358 100.0
HFD2_k127_2058707_1 - - - - 0.000000007835 68.0
HFD2_k127_2067435_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 8.743e-237 741.0
HFD2_k127_2067435_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000009939 149.0
HFD2_k127_2069183_0 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 589.0
HFD2_k127_2069183_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000001911 141.0
HFD2_k127_2069183_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.3.5.6,6.3.5.7 0.00000000000000004951 84.0
HFD2_k127_2069183_3 protein conserved in bacteria K09800 - - 0.0000000000008091 81.0
HFD2_k127_2082099_0 Molydopterin dinucleotide binding domain K17050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 533.0
HFD2_k127_2082099_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 421.0
HFD2_k127_2116664_0 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 431.0
HFD2_k127_2116664_1 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004917 297.0
HFD2_k127_2116664_2 PFAM NADH Ubiquinone plastoquinone (complex I) K12141 - - 0.000000000000000000000000000000000000000000000000000000000000000000001666 244.0
HFD2_k127_2116664_3 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000003063 201.0
HFD2_k127_2116664_4 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000004847 125.0
HFD2_k127_2134581_0 M13 family peptidase K01415,K07386 - 3.4.24.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 373.0
HFD2_k127_2134581_1 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.00000000000000000000067 112.0
HFD2_k127_2140338_0 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 2.324e-298 927.0
HFD2_k127_2140338_1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008564 456.0
HFD2_k127_21538_0 Protein kinase domain K12132 - 2.7.11.1 4.639e-215 697.0
HFD2_k127_21538_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 492.0
HFD2_k127_21538_2 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009336 312.0
HFD2_k127_21538_3 TIGRFAM RNA polymerase sigma-54 factor K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 300.0
HFD2_k127_21538_4 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000000000000000000000001025 213.0
HFD2_k127_21538_5 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000002067 186.0
HFD2_k127_21538_6 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000002164 114.0
HFD2_k127_2164323_0 Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues K01791,K08068 GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008761,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0033692,GO:0034637,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046378,GO:0071704,GO:1901135,GO:1901137,GO:1901576 3.2.1.183,5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005481 371.0
HFD2_k127_2164323_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 349.0
HFD2_k127_2164323_2 PFAM peptidase M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 304.0
HFD2_k127_2164323_3 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003842 277.0
HFD2_k127_2164323_4 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002671 261.0
HFD2_k127_2164323_5 transferase activity, transferring glycosyl groups K12996 - - 0.0000000000000000000000000000000000000000000000000000000000000000001179 244.0
HFD2_k127_2164323_6 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000005029 234.0
HFD2_k127_2164323_7 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.000000000000000000000000000000000000002548 156.0
HFD2_k127_2164323_8 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.0000000000000009201 78.0
HFD2_k127_2168503_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 550.0
HFD2_k127_2168503_1 helicase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006731 275.0
HFD2_k127_2168503_2 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001277 258.0
HFD2_k127_2168503_3 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000006644 201.0
HFD2_k127_2170001_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 327.0
HFD2_k127_2170001_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0003497 47.0
HFD2_k127_2174322_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 1.969e-247 784.0
HFD2_k127_2174322_1 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 484.0
HFD2_k127_2174322_2 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 4.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 401.0
HFD2_k127_2174322_3 - - - - 0.0000000000000000000000000000000000000000000000000001537 190.0
HFD2_k127_2174322_4 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000004583 186.0
HFD2_k127_2174322_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000005083 132.0
HFD2_k127_2174322_6 Cysteine-rich secretory protein family - - - 0.00000000000000000000003115 109.0
HFD2_k127_2174322_7 decarboxylase K01607 - 4.1.1.44 0.000000000000001333 89.0
HFD2_k127_2174322_8 Belongs to the ompA family K20276 - - 0.00001781 58.0
HFD2_k127_217885_0 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 313.0
HFD2_k127_217885_1 PrkA AAA domain K07180 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 293.0
HFD2_k127_217885_2 gtp cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000003751 253.0
HFD2_k127_217885_3 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000003474 179.0
HFD2_k127_217885_4 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000000003417 158.0
HFD2_k127_217885_5 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059,K07124 - 1.1.1.100 0.00000000000000000000000000000000008553 140.0
HFD2_k127_217885_6 acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.0000000000000000000000000000000005625 136.0
HFD2_k127_2179412_0 Ferredoxin-fold anticodon binding domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 454.0
HFD2_k127_2179412_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 375.0
HFD2_k127_2179412_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 - 0.000000000000000000000000000000000000000000000000000001462 201.0
HFD2_k127_2179412_3 threonyl-tRNA aminoacylation K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.000000000000000000000000000000000000000000000000001299 186.0
HFD2_k127_2179412_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000002472 140.0
HFD2_k127_2179412_5 Ribosomal protein L35 K02916 - - 0.000000000004418 68.0
HFD2_k127_2184377_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006774 486.0
HFD2_k127_2184377_1 ATP synthesis coupled electron transport K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 395.0
HFD2_k127_2184377_2 PFAM RNA binding S1 domain protein K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005252 309.0
HFD2_k127_2184377_3 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000001547 114.0
HFD2_k127_2184377_4 NADH-quinone oxidoreductase chain L K00341 - 1.6.5.3 0.00000000000000000000000003261 117.0
HFD2_k127_2184377_5 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000002501 53.0
HFD2_k127_219916_0 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 476.0
HFD2_k127_219916_1 6-phosphofructokinase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 460.0
HFD2_k127_219916_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 446.0
HFD2_k127_219916_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004619 283.0
HFD2_k127_219916_4 - - - - 0.000000000000003391 85.0
HFD2_k127_219916_5 Preprotein translocase SecG subunit K03075 - - 0.0000000006729 66.0
HFD2_k127_2211366_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 434.0
HFD2_k127_2211366_1 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000002841 233.0
HFD2_k127_2211366_2 GAF domain - - - 0.00000000000000000000000000000000000000000001665 181.0
HFD2_k127_2220037_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.0 1020.0
HFD2_k127_2220037_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000003459 74.0
HFD2_k127_2220037_2 Domain of unknown function (DUF4440) - - - 0.000000000000255 79.0
HFD2_k127_2225889_0 PFAM NAD-dependent epimerase dehydratase K15856 - 1.1.1.281 0.0000000000000000000000000000000000000000000000000000003477 205.0
HFD2_k127_2225949_0 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000746 285.0
HFD2_k127_2225949_1 Putative stress-induced transcription regulator - - - 0.00000000000000000000000000000003338 134.0
HFD2_k127_2225949_2 DinB superfamily - - - 0.00000000000000000000000001911 117.0
HFD2_k127_2225949_3 protein secretion K09800 - - 0.00000001263 66.0
HFD2_k127_2243326_0 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 485.0
HFD2_k127_2243326_1 Cysteine-rich domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 371.0
HFD2_k127_2243326_2 pectinesterase activity - - - 0.0003382 54.0
HFD2_k127_224781_0 Peptidase family C25 - - - 0.00000000000000000000003051 117.0
HFD2_k127_224781_1 agmatine deiminase activity K08589,K10536,K20276 GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.22.37,3.5.3.12 0.0008036 52.0
HFD2_k127_2252398_1 Rhodanese-like domain - - - 0.000000000000000000000000000000001195 138.0
HFD2_k127_2252398_2 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.0002323 46.0
HFD2_k127_226818_0 peptidase activity, acting on L-amino acid peptides K07004,K09955 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 424.0
HFD2_k127_226818_1 Phosphate transport system permease K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 362.0
HFD2_k127_226818_2 His Kinase A (phosphoacceptor) domain K02484,K07636,K07768 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 371.0
HFD2_k127_226818_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 347.0
HFD2_k127_226818_4 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 340.0
HFD2_k127_226818_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 317.0
HFD2_k127_226818_6 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001747 257.0
HFD2_k127_226818_7 PFAM response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000000000000000000000000000000000000000000000002559 227.0
HFD2_k127_226818_8 phosphate-selective porin O and P - - - 0.0000000000000000000000000000000000000000000000001404 192.0
HFD2_k127_2268488_0 manganese ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000933 186.0
HFD2_k127_2268488_1 Haem-binding domain - - - 0.000000000000000000000000000000000000000512 153.0
HFD2_k127_2268488_2 - - - - 0.000000000001219 77.0
HFD2_k127_2268488_3 Cytochrome c554 and c-prime K01119 - 3.1.3.6,3.1.4.16 0.000000005577 63.0
HFD2_k127_2274764_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 352.0
HFD2_k127_2274764_1 Beta-Casp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003987 269.0
HFD2_k127_2274764_2 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000003159 246.0
HFD2_k127_2274764_3 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000001384 66.0
HFD2_k127_2274764_4 Two component signalling adaptor domain K03408 - - 0.0009972 48.0
HFD2_k127_2275501_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1129.0
HFD2_k127_2275501_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 406.0
HFD2_k127_2275501_2 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002023 285.0
HFD2_k127_2275501_3 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000001399 181.0
HFD2_k127_2275501_4 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000001313 173.0
HFD2_k127_2275501_5 PFAM Peptidase family M23 - - - 0.0000000000000000000000000000000000004429 162.0
HFD2_k127_2275501_6 Belongs to the UPF0434 family K09791 - - 0.000000000000009174 78.0
HFD2_k127_2275501_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000001315 69.0
HFD2_k127_2276611_0 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 413.0
HFD2_k127_2276611_1 NAD(P)H-binding - - - 0.000000000000000000000000000000000000001265 169.0
HFD2_k127_2280914_0 ATP synthesis coupled electron transport K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 341.0
HFD2_k127_2280914_1 quinone binding K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 294.0
HFD2_k127_2285406_0 - - - - 0.00000000000000000181 96.0
HFD2_k127_2285406_1 - - - - 0.0000000000147 73.0
HFD2_k127_2297208_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 523.0
HFD2_k127_2305328_0 pilus assembly protein K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 323.0
HFD2_k127_2305328_1 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000008904 97.0
HFD2_k127_2305328_2 Pilus assembly protein, PilO K02664 - - 0.00000000000000000008567 96.0
HFD2_k127_2305328_3 PFAM Fimbrial assembly family protein K02663 - - 0.0000000005388 70.0
HFD2_k127_2309654_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000001329 229.0
HFD2_k127_2309654_1 RIO1 family K01090,K12132 - 2.7.11.1,3.1.3.16 0.00000000000000006846 87.0
HFD2_k127_2325594_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000389 226.0
HFD2_k127_2330202_0 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 389.0
HFD2_k127_2330202_1 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000001755 182.0
HFD2_k127_2330202_2 endonuclease activity K07451 - - 0.000000000000000000000001894 111.0
HFD2_k127_2330202_3 endonuclease activity K07451 - - 0.000000001377 66.0
HFD2_k127_2337810_0 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 446.0
HFD2_k127_2337810_1 Male sterility protein K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000006603 238.0
HFD2_k127_2371881_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.0000000003034 68.0
HFD2_k127_237865_0 saccharopine dehydrogenase activity K19064 - 1.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 301.0
HFD2_k127_237865_1 Endonuclease I K07004 - - 0.0003761 47.0
HFD2_k127_2388261_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 338.0
HFD2_k127_2388261_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 293.0
HFD2_k127_2388261_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000142 245.0
HFD2_k127_2388261_3 Abc transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000005008 229.0
HFD2_k127_2388261_4 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000004318 150.0
HFD2_k127_2388261_5 cellulose binding - - - 0.00000000000000000000000000002423 129.0
HFD2_k127_2388261_6 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.00003309 55.0
HFD2_k127_2404652_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 419.0
HFD2_k127_2404652_1 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004324 280.0
HFD2_k127_2404652_2 Pirin C-terminal cupin domain K06911 - - 0.0000000000000000000000000000000000000000000000000000000001196 204.0
HFD2_k127_2406518_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 2.12e-227 711.0
HFD2_k127_2406518_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001766 244.0
HFD2_k127_2406518_2 Enolase, C-terminal TIM barrel domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002174 239.0
HFD2_k127_2409076_0 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002293 284.0
HFD2_k127_2409076_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.0000000000000000000000000000000000000000000000000004587 188.0
HFD2_k127_2409076_2 cell redox homeostasis K03671,K07152 - - 0.0000000000000000000000000000000000000000357 162.0
HFD2_k127_2409076_3 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000000000000005473 145.0
HFD2_k127_2409076_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000001537 119.0
HFD2_k127_2409076_5 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000008141 87.0
HFD2_k127_2410527_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000001821 196.0
HFD2_k127_2410527_1 Protein of unknown function, DUF255 - - - 0.0000000001139 69.0
HFD2_k127_2410527_2 - - - - 0.00004497 54.0
HFD2_k127_2410527_3 NHL repeat containing protein - - - 0.0002258 54.0
HFD2_k127_2426975_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 3.066e-287 902.0
HFD2_k127_2426975_1 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 455.0
HFD2_k127_2436218_0 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008533 248.0
HFD2_k127_2438012_0 Chaperone - - - 0.000000000000000000000000006454 125.0
HFD2_k127_2487161_0 glycyl-tRNA aminoacylation K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 473.0
HFD2_k127_2487161_1 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 361.0
HFD2_k127_2487161_2 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.0000000005226 60.0
HFD2_k127_2492435_1 HNH endonuclease - - - 0.000000003616 68.0
HFD2_k127_2510730_0 COG0433 Predicted ATPase K06915 - - 1.826e-259 812.0
HFD2_k127_2510730_1 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 358.0
HFD2_k127_2510730_2 Belongs to the N-Me-Phe pilin family - - - 0.00000000000000000000000001185 111.0
HFD2_k127_2533692_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 521.0
HFD2_k127_2533692_1 Glucose-6-phosphate dehydrogenase subunit - - - 0.0000000000000000004869 96.0
HFD2_k127_2537627_0 M3B, thimet oligopeptidase F K08602 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 308.0
HFD2_k127_2537627_1 DNA replication, synthesis of RNA primer K04066 - - 0.000000000000000000000000000000000000000000000000001761 199.0
HFD2_k127_2537627_2 membrane K08978 - - 0.000000000000000000000000000000000000000000003543 169.0
HFD2_k127_2539623_0 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 331.0
HFD2_k127_2539623_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001079 241.0
HFD2_k127_2539623_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000003088 225.0
HFD2_k127_2539623_3 peroxiredoxin, OsmC subfamily K04063 - - 0.00000000000000000000000000000000000000000002175 168.0
HFD2_k127_2542031_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 391.0
HFD2_k127_2546299_0 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 402.0
HFD2_k127_2546299_1 CHRD domain - - - 0.000000000000000000000000000000000000000000001021 173.0
HFD2_k127_2546299_2 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000000000000000000000000000000000000001218 158.0
HFD2_k127_2546299_3 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000139 81.0
HFD2_k127_2546299_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000824 64.0
HFD2_k127_2546299_5 Evidence 5 No homology to any previously reported sequences K03088 - - 0.0000000003182 74.0
HFD2_k127_2547049_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 426.0
HFD2_k127_2547049_1 heme-binding sites - - - 0.00000000000000000000000000000002288 146.0
HFD2_k127_2547049_2 NAD dependent epimerase/dehydratase family - - - 0.000000001061 64.0
HFD2_k127_2547049_3 cellulose binding K00505 - 1.14.18.1 0.00000001324 68.0
HFD2_k127_2549871_0 Acyl-CoA dehydrogenase, N-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 426.0
HFD2_k127_2549871_1 Coenzyme A transferase K01027,K01029,K01040 - 2.8.3.12,2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000007886 248.0
HFD2_k127_258790_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 374.0
HFD2_k127_258790_1 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000002041 218.0
HFD2_k127_258790_2 Regulatory protein, FmdB family - - - 0.000000000000000000000001032 107.0
HFD2_k127_258790_3 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000001215 98.0
HFD2_k127_258790_4 Armadillo/beta-catenin-like repeats - - - 0.00004278 53.0
HFD2_k127_258790_5 lipid A biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.0003695 46.0
HFD2_k127_2589726_0 Domains REC, sigma54 interaction, HTH8 K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 426.0
HFD2_k127_2589726_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000006193 203.0
HFD2_k127_2589726_2 cellulase activity K01178,K14645,K18546 - 3.2.1.3 0.00000000000000000002326 106.0
HFD2_k127_2589726_3 TIGRFAM exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.00000000000000000003233 99.0
HFD2_k127_2609374_0 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 460.0
HFD2_k127_2609374_1 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000001008 187.0
HFD2_k127_2613570_0 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 310.0
HFD2_k127_2613570_1 - - - - 0.00000000000000000000000000000000000000000000002644 186.0
HFD2_k127_2613570_2 gluconolactonase activity K00368,K07004 - 1.7.2.1 0.0001116 51.0
HFD2_k127_2614206_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 312.0
HFD2_k127_2614206_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 294.0
HFD2_k127_2614206_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01450,K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.31,3.5.1.88 0.00000000000000000000000000000000003186 141.0
HFD2_k127_2614206_3 Preprotein translocase, YajC K03210 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000002198 87.0
HFD2_k127_2644779_0 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000003351 185.0
HFD2_k127_2644779_1 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000001538 168.0
HFD2_k127_2644779_2 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000003774 152.0
HFD2_k127_2644779_3 PhoQ Sensor - - - 0.000000000000000000000000000000000009825 138.0
HFD2_k127_2644779_4 AntiSigma factor - - - 0.00000000000000000000000000003005 128.0
HFD2_k127_2647847_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 437.0
HFD2_k127_2647847_1 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 426.0
HFD2_k127_2647847_10 - - - - 0.000000005186 66.0
HFD2_k127_2647847_2 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 385.0
HFD2_k127_2647847_3 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 337.0
HFD2_k127_2647847_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006204 271.0
HFD2_k127_2647847_5 Protein of unknown function (DUF1572) - - - 0.00000000000000000000000000000000000000000000000000000000000004052 219.0
HFD2_k127_2647847_6 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000007621 152.0
HFD2_k127_2647847_7 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.0000000000000000000000000001678 124.0
HFD2_k127_2647847_8 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000002395 109.0
HFD2_k127_2647847_9 extracellular matrix structural constituent - - - 0.000000000000009447 85.0
HFD2_k127_2656300_0 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000002385 158.0
HFD2_k127_2656300_1 Thioredoxin - - - 0.00000000000000000909 94.0
HFD2_k127_2664517_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 6.522e-278 875.0
HFD2_k127_2664517_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 562.0
HFD2_k127_2664517_10 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000005163 55.0
HFD2_k127_2664517_11 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E K06019 - 3.6.1.1 0.0001073 46.0
HFD2_k127_2664517_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 490.0
HFD2_k127_2664517_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 477.0
HFD2_k127_2664517_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 311.0
HFD2_k127_2664517_5 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 299.0
HFD2_k127_2664517_6 PFAM aminotransferase class V - - - 0.000000000000000000000000000000000000000000000000000000000000004039 226.0
HFD2_k127_2664517_7 PFAM aminotransferase class V - - - 0.0000000000000000000000000000003081 130.0
HFD2_k127_2664517_8 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000000004228 81.0
HFD2_k127_2664517_9 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000004646 84.0
HFD2_k127_2666126_0 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000007526 204.0
HFD2_k127_2666126_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000009464 187.0
HFD2_k127_2666126_2 protein transport K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000000000000000007877 140.0
HFD2_k127_2666126_3 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000000000009189 80.0
HFD2_k127_2671904_0 PFAM DAHP synthetase I K03856,K04516 - 2.5.1.54,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000001934 246.0
HFD2_k127_2671904_1 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000001831 214.0
HFD2_k127_2671904_2 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000000000000004142 169.0
HFD2_k127_2693024_0 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 348.0
HFD2_k127_2695056_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007626 398.0
HFD2_k127_2695056_1 - - - - 0.000000000000000000000000000000000000004247 160.0
HFD2_k127_2695056_2 photoreceptor activity K02658,K04757,K13924,K17752 - 2.1.1.80,2.7.11.1,3.1.1.61 0.00000000000000000000000000000005818 129.0
HFD2_k127_2695056_3 Aldo/keto reductase family - - - 0.00000000000000000000000004816 121.0
HFD2_k127_27062_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 435.0
HFD2_k127_27062_1 elongation factor G K02355 - - 0.0000000000000000000000000000000000000000000000000000000004382 207.0
HFD2_k127_2707968_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009347 461.0
HFD2_k127_2707968_1 PFAM transferase hexapeptide repeat containing protein K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 410.0
HFD2_k127_2707968_10 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000001012 72.0
HFD2_k127_2707968_11 amine dehydrogenase activity - - - 0.000003229 59.0
HFD2_k127_2707968_2 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003336 269.0
HFD2_k127_2707968_3 Immune inhibitor A peptidase M6 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000678 261.0
HFD2_k127_2707968_4 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000007929 237.0
HFD2_k127_2707968_5 long-chain fatty acid transport protein - - - 0.00000000000000000000000000000000000000000001153 176.0
HFD2_k127_2707968_6 phosphatidate phosphatase activity K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.00000000000000000000006494 106.0
HFD2_k127_2707968_7 Ethanolamine utilisation protein EutN/carboxysome - - - 0.000000000000000000001191 98.0
HFD2_k127_2707968_8 BMC - - - 0.00000000000000000001094 102.0
HFD2_k127_2720419_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1091.0
HFD2_k127_2720419_1 Aldehyde dehydrogenase family K00128,K00135,K22187 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 388.0
HFD2_k127_2720419_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000626 179.0
HFD2_k127_272291_0 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001754 264.0
HFD2_k127_272291_1 - - - - 0.000000000000000000000000000000000000000000000000005316 190.0
HFD2_k127_272291_2 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000002732 184.0
HFD2_k127_272291_3 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000006273 171.0
HFD2_k127_272291_4 COG1512 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.000000000000000000000000000000000000005248 153.0
HFD2_k127_272291_5 Lysin motif - - - 0.00000000000000000004539 94.0
HFD2_k127_272291_6 - - - - 0.000000000000008399 85.0
HFD2_k127_2736849_0 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 413.0
HFD2_k127_2736849_1 NmrA-like family K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 381.0
HFD2_k127_2736849_2 Pfam:DUF303 K05970 - 3.1.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 377.0
HFD2_k127_2736849_3 Zn-dependent proteases and their inactivated homologs K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 309.0
HFD2_k127_2736849_4 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000004021 191.0
HFD2_k127_2765386_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000003213 175.0
HFD2_k127_2765386_1 Surface antigen - - - 0.000000000000000000000000000000000002463 156.0
HFD2_k127_2765386_2 SNARE associated Golgi protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000001997 58.0
HFD2_k127_2765743_0 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 584.0
HFD2_k127_2765743_1 glycine decarboxylation via glycine cleavage system K02437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004797 307.0
HFD2_k127_2765743_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 305.0
HFD2_k127_2765743_3 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006918 283.0
HFD2_k127_2765743_4 molybdopterin cofactor binding - - - 0.00000000000000000000000000000000000000000000000000000000004657 231.0
HFD2_k127_2765743_5 PFAM cytochrome c class III - - - 0.000000000000000000000000000000000000000000000000000005249 199.0
HFD2_k127_2765743_6 glycine decarboxylation via glycine cleavage system K02437 - - 0.00000003718 59.0
HFD2_k127_2772111_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 511.0
HFD2_k127_2772111_1 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 465.0
HFD2_k127_2772111_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001187 277.0
HFD2_k127_2772111_3 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000000007477 187.0
HFD2_k127_2772111_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000001642 152.0
HFD2_k127_2772111_5 Belongs to the SUA5 family K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.0000000000000000000000002192 113.0
HFD2_k127_2775723_0 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000337 247.0
HFD2_k127_2775723_1 Belongs to the peptidase S8 family K14743 - - 0.0000000000000000000000000000000000000004894 167.0
HFD2_k127_2786260_0 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000009799 238.0
HFD2_k127_2786260_1 DGC domain - - - 0.000000000000000000000000000000000000007143 156.0
HFD2_k127_2786260_2 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.000000000000000000000003467 120.0
HFD2_k127_2786260_3 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000002574 64.0
HFD2_k127_2786260_4 FlgD Ig-like domain - - - 0.00002968 58.0
HFD2_k127_2786260_5 - - - - 0.0006485 52.0
HFD2_k127_2792780_0 ligase activity, forming nitrogen-metal bonds K02230 - 6.6.1.2 0.0 1045.0
HFD2_k127_2792780_1 gluconolactonase activity K01053 - 3.1.1.17 3.696e-194 623.0
HFD2_k127_2792780_2 Cupin 2, conserved barrel domain protein K11477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 326.0
HFD2_k127_2794320_0 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 334.0
HFD2_k127_2794320_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000004447 151.0
HFD2_k127_2794320_2 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000003551 100.0
HFD2_k127_2794320_3 von Willebrand factor type A domain K07114 - - 0.00000008183 65.0
HFD2_k127_2795214_0 TIGRFAM methylmalonyl-CoA mutase N-terminal domain K01848 - 5.4.99.2 1.026e-231 729.0
HFD2_k127_2795214_1 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007615 322.0
HFD2_k127_2795214_2 3-oxoacid CoA-transferase, B subunit K01029 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 294.0
HFD2_k127_2795214_3 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008155 278.0
HFD2_k127_2795214_4 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000005688 211.0
HFD2_k127_2800170_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 317.0
HFD2_k127_2800170_1 Dehydrogenase E1 component K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 298.0
HFD2_k127_2800170_2 Putative glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000001634 196.0
HFD2_k127_2800170_3 Glycosyl transferase family 2 - - - 0.00000000000000000000000204 104.0
HFD2_k127_2800170_4 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000001422 85.0
HFD2_k127_2800170_5 oxidoreductase activity - - - 0.0000003712 55.0
HFD2_k127_2800170_6 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - 0.000002586 61.0
HFD2_k127_2800170_7 Lamin Tail Domain - - - 0.000002662 57.0
HFD2_k127_2800170_8 LVIVD repeat K01179 - 3.2.1.4 0.00003428 49.0
HFD2_k127_2805092_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008469 387.0
HFD2_k127_2805785_0 Ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 338.0
HFD2_k127_2805785_1 ECF sigma factor - - - 0.000000000000000000000000000000000000000001445 164.0
HFD2_k127_2805785_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000005333 79.0
HFD2_k127_2823517_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 583.0
HFD2_k127_2823517_1 Bacterial regulatory protein, arsR family - - - 0.00000000000000000000000000000000000001169 150.0
HFD2_k127_2823517_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000005349 139.0
HFD2_k127_2823517_3 permeases K07088 - - 0.00000000000000000000002412 111.0
HFD2_k127_2823517_4 radical SAM K06871 - - 0.000002324 59.0
HFD2_k127_2823517_5 Fibronectin type 3 domain - - - 0.0001711 53.0
HFD2_k127_2825594_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005628 271.0
HFD2_k127_2825594_1 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000003299 109.0
HFD2_k127_2825594_2 Belongs to the peptidase S8 family K01337,K01387,K05994,K08604,K14645,K20276 - 3.4.11.10,3.4.21.50,3.4.24.25,3.4.24.3 0.000000001535 68.0
HFD2_k127_2833711_0 Short chain fatty acid transporter K02106 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 465.0
HFD2_k127_2833711_1 PFAM Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 408.0
HFD2_k127_2833711_2 creatininase K01470 - 3.5.2.10 0.0001907 45.0
HFD2_k127_2834454_0 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 307.0
HFD2_k127_2834454_1 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000001854 168.0
HFD2_k127_2845786_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 401.0
HFD2_k127_2845786_1 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 328.0
HFD2_k127_2845786_2 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000007201 135.0
HFD2_k127_2845786_3 PFAM Methyltransferase type 11 - - - 0.00000000000000000000002502 112.0
HFD2_k127_2869409_0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00262 - 1.4.1.4 1.564e-252 784.0
HFD2_k127_2869409_1 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 530.0
HFD2_k127_2869409_2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.000000000000000000000000000000000000000000005278 169.0
HFD2_k127_2904916_0 Pirin K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009966 346.0
HFD2_k127_2904916_1 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000008111 166.0
HFD2_k127_2904916_2 Transcriptional regulator K03709 - - 0.0000000000000000000000000002232 118.0
HFD2_k127_2904916_3 MacB-like periplasmic core domain K02004 - - 0.000000000003181 67.0
HFD2_k127_293904_0 protein conserved in bacteria K11896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 562.0
HFD2_k127_293904_1 COG0542 ATPases with chaperone activity, ATP-binding subunit K11907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 359.0
HFD2_k127_293904_2 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.00000000000000000000000000000000000000000000000000000004155 204.0
HFD2_k127_293904_3 Type VI secretion, TssG K11895 - - 0.00000000000000000000000000000000000000000000000008403 203.0
HFD2_k127_293904_4 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000003514 166.0
HFD2_k127_293904_5 PFAM beta-lactamase - - - 0.00000000000000000000000000000000000001292 163.0
HFD2_k127_293904_6 Gene 25-like lysozyme K11905 - - 0.00000000000000000000001864 109.0
HFD2_k127_293904_8 cellulose binding - - - 0.00000000005481 73.0
HFD2_k127_2958388_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 316.0
HFD2_k127_2958388_1 DoxX - - - 0.000000000000000000000000000000000000000002399 165.0
HFD2_k127_2958388_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000001882 118.0
HFD2_k127_2958388_3 - - - - 0.000000000000005091 80.0
HFD2_k127_296211_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 537.0
HFD2_k127_296211_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008831 370.0
HFD2_k127_296211_3 TatD related DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000001605 80.0
HFD2_k127_2970122_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 399.0
HFD2_k127_2970122_1 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002432 277.0
HFD2_k127_2970122_2 Polypeptide deformylase - - - 0.0000000000000000000000000000000000000000000000000001984 193.0
HFD2_k127_2970122_3 Acid phosphatase homologues - - - 0.0000000000000000000000000000000000000007126 162.0
HFD2_k127_2970122_4 hyperosmotic response - - - 0.0000000000000000000000000000004328 134.0
HFD2_k127_2970122_5 Methyltransferase type 11 - - - 0.00000000000000000000000000007381 120.0
HFD2_k127_2970122_6 Domain of unknown function (DUF362) - - - 0.0000000000000000542 81.0
HFD2_k127_2970122_7 CAAX protease self-immunity - - - 0.00008682 53.0
HFD2_k127_298862_0 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 377.0
HFD2_k127_298862_1 PTS system sorbose subfamily IIB component K02794,K19507 - 2.7.1.191 0.0000000000000000000000000000005887 127.0
HFD2_k127_298862_2 PTS system fructose IIA component K02793 - 2.7.1.191 0.0000002242 58.0
HFD2_k127_3001936_0 GHMP kinases C terminal K07031 - 2.7.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 414.0
HFD2_k127_3001936_1 Polysaccharide biosynthesis protein K01784,K08679 - 5.1.3.2,5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 344.0
HFD2_k127_3001936_2 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 321.0
HFD2_k127_3001936_3 Protein of unknown function (DUF2723) - - - 0.000000000000000000000000000000000000000000000000000000000001363 225.0
HFD2_k127_3001936_4 COGs COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000003798 153.0
HFD2_k127_3013543_0 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 378.0
HFD2_k127_3013543_1 Methyltransferase domain - - - 0.0000000000000000000000000001026 132.0
HFD2_k127_3017499_0 TPR Domain containing protein K12600 - - 0.000000000007994 76.0
HFD2_k127_3027202_0 Rhomboid family - - - 0.00000000000000000000000000000000000000000006149 165.0
HFD2_k127_3027202_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000864 133.0
HFD2_k127_3037362_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 366.0
HFD2_k127_3037362_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000004765 258.0
HFD2_k127_3037362_2 Binds directly to 16S ribosomal RNA K02968 - - 0.00000002226 58.0
HFD2_k127_3037362_3 Bacterial Ig-like domain - - - 0.0003104 53.0
HFD2_k127_3043804_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 6.208e-200 641.0
HFD2_k127_3043804_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 459.0
HFD2_k127_3043804_2 Peptidase, M16 K07263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 444.0
HFD2_k127_3043804_3 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 325.0
HFD2_k127_3043804_4 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000006629 243.0
HFD2_k127_3043804_5 ABC 3 transport family K02075 - - 0.00000000000000000000000000000000000000000000000000000000000946 216.0
HFD2_k127_3043804_6 Belongs to the bacterial solute-binding protein 9 family K02077 - - 0.000000000000000000000000000000000000000000000006461 186.0
HFD2_k127_3043804_7 - - - - 0.0000000000000000006428 99.0
HFD2_k127_3043804_8 PFAM blue (type 1) copper domain protein - - - 0.00005015 54.0
HFD2_k127_3048523_0 ABC-type dipeptide transport system periplasmic component K02035 - - 1.667e-214 683.0
HFD2_k127_3048523_1 ABC transporter permease K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 456.0
HFD2_k127_3048523_2 xyloglucan:xyloglucosyl transferase activity K01216,K07004 - 3.2.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 432.0
HFD2_k127_3048523_3 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 433.0
HFD2_k127_3048523_4 ABC transporter permease K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 368.0
HFD2_k127_3048523_5 Glycosyl hydrolases family 16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 304.0
HFD2_k127_3049362_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 604.0
HFD2_k127_3049362_1 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 377.0
HFD2_k127_3049362_2 CDP-alcohol phosphatidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003504 237.0
HFD2_k127_3049362_3 Alpha-amylase domain K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.000000000000000000000000000000000000000000000002173 184.0
HFD2_k127_3049362_4 Tetratricopeptide repeat - - - 0.000000000000000000000001706 120.0
HFD2_k127_3049362_5 Domain of unknown function (DUF4215) - - - 0.00000002796 66.0
HFD2_k127_3067157_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.901e-270 871.0
HFD2_k127_3067157_1 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 475.0
HFD2_k127_3067157_2 cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000000000000000000000003204 202.0
HFD2_k127_3067157_3 PPIC-type PPIASE domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000002491 205.0
HFD2_k127_3067157_4 Peptidase family M23 K21471 GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.000000000000000000000000000000000000000000004204 186.0
HFD2_k127_3067157_5 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.0000000000000000000000000000000000007137 153.0
HFD2_k127_3067157_6 oxidoreductase activity - - - 0.0000000000000000000001693 111.0
HFD2_k127_3067157_7 S4 RNA-binding domain - GO:0008150,GO:0040007 - 0.000000000000005229 83.0
HFD2_k127_3067157_8 DNA polymerase III K02341 GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 0.00000000000009157 77.0
HFD2_k127_3076779_0 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000554 125.0
HFD2_k127_3076779_1 DNA-binding transcription factor activity - - - 0.00000000000000001425 89.0
HFD2_k127_3076779_2 protein kinase activity - - - 0.00001082 58.0
HFD2_k127_3093154_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006228 273.0
HFD2_k127_3093154_1 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000004071 173.0
HFD2_k127_3093154_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000133 118.0
HFD2_k127_3093154_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000001333 93.0
HFD2_k127_311448_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 387.0
HFD2_k127_3130754_0 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000002533 222.0
HFD2_k127_3130754_1 COG0534 Na -driven multidrug efflux pump - - - 0.0000000000000178 80.0
HFD2_k127_3132249_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 479.0
HFD2_k127_3132249_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 351.0
HFD2_k127_3132249_2 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001035 282.0
HFD2_k127_3132249_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000002928 149.0
HFD2_k127_3155815_0 4-hydroxyphenylacetate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 574.0
HFD2_k127_3155815_1 Acyl-CoA dehydrogenase, C-terminal domain K18244 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 419.0
HFD2_k127_3155815_11 nucleotidyltransferase activity K07076 - - 0.000000000005333 74.0
HFD2_k127_3155815_12 Belongs to the UPF0178 family K09768 - - 0.00000001092 58.0
HFD2_k127_3155815_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 310.0
HFD2_k127_3155815_3 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000006403 278.0
HFD2_k127_3155815_4 PFAM Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000009221 225.0
HFD2_k127_3155815_5 glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000001015 203.0
HFD2_k127_3155815_6 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000001815 196.0
HFD2_k127_3155815_7 Methyltransferase domain K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000002512 164.0
HFD2_k127_3155815_8 Higher Eukarytoes and Prokaryotes Nucleotide-binding domain - - - 0.0000000000000000000000002628 110.0
HFD2_k127_3155815_9 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.00000000000000000000006194 101.0
HFD2_k127_3162155_0 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.0 1395.0
HFD2_k127_3162155_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 481.0
HFD2_k127_3162155_2 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003539 246.0
HFD2_k127_3162942_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 586.0
HFD2_k127_3189698_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 524.0
HFD2_k127_3189698_1 Proton-conducting membrane transporter K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000001106 241.0
HFD2_k127_3189698_2 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000002601 242.0
HFD2_k127_3190209_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 1.728e-214 678.0
HFD2_k127_3190209_1 PFAM adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000931 46.0
HFD2_k127_3204250_0 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004592 283.0
HFD2_k127_3204250_1 TfoX N-terminal domain - - - 0.0000009897 60.0
HFD2_k127_3204612_0 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 310.0
HFD2_k127_3204612_1 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003396 270.0
HFD2_k127_3224254_0 Multicopper oxidase K06324 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 482.0
HFD2_k127_3224254_1 AlkA N-terminal domain K13529,K13530 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000001793 259.0
HFD2_k127_3224254_2 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000005484 192.0
HFD2_k127_3224254_3 Histidine kinase - - - 0.0000000000000000000000000000000002715 151.0
HFD2_k127_3224254_4 - - - - 0.0001543 52.0
HFD2_k127_3251515_0 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 386.0
HFD2_k127_3251515_1 endonuclease activity K07451 - - 0.0000000000000000002261 96.0
HFD2_k127_3261081_0 Peptidase family M28 K05994 - 3.4.11.10 0.000000000000000000000002252 119.0
HFD2_k127_3262805_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 4.036e-207 667.0
HFD2_k127_3262805_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 418.0
HFD2_k127_3262805_10 transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000000000647 136.0
HFD2_k127_3262805_11 TIGRFAM amino acid adenylation domain - - - 0.000006864 59.0
HFD2_k127_3262805_2 tRNA processing K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001071 263.0
HFD2_k127_3262805_3 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000002017 212.0
HFD2_k127_3262805_4 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.00000000000000000000000000000000000000000000000001072 194.0
HFD2_k127_3262805_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000003892 187.0
HFD2_k127_3262805_6 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.00000000000000000000000000000000000000000008011 182.0
HFD2_k127_3262805_7 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000001073 168.0
HFD2_k127_3262805_8 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000002779 147.0
HFD2_k127_3262805_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000006878 154.0
HFD2_k127_3288014_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 396.0
HFD2_k127_3288014_1 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 365.0
HFD2_k127_3288014_2 e3 binding domain K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000004981 175.0
HFD2_k127_3292084_0 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002026 266.0
HFD2_k127_3292084_1 nuclear chromosome segregation - - - 0.0000000000000000000000000000000002995 150.0
HFD2_k127_3300855_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 616.0
HFD2_k127_3300855_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006183 469.0
HFD2_k127_3300855_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 397.0
HFD2_k127_3300855_3 Metal-dependent phosphohydrolase, HD region - - - 0.0000000000000000000000000000000001062 137.0
HFD2_k127_3300855_4 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07668 GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000004686 75.0
HFD2_k127_3300855_5 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000001073 65.0
HFD2_k127_3300855_6 - - - - 0.00000003001 61.0
HFD2_k127_3300855_7 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000008049 58.0
HFD2_k127_3300855_8 Subtilase family - - - 0.000005938 59.0
HFD2_k127_331473_0 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000004971 217.0
HFD2_k127_331473_1 protein involved in exopolysaccharide biosynthesis K16554 - - 0.000000000000001719 85.0
HFD2_k127_3315475_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 6.716e-218 704.0
HFD2_k127_3315475_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 355.0
HFD2_k127_3315475_2 Phage integrase, N-terminal SAM-like domain K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000001977 209.0
HFD2_k127_3315475_3 - - - - 0.0000000000001016 75.0
HFD2_k127_331613_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000009777 244.0
HFD2_k127_331613_1 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000838 211.0
HFD2_k127_331613_2 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000002414 178.0
HFD2_k127_331613_3 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000001457 136.0
HFD2_k127_331613_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000001011 88.0
HFD2_k127_331613_5 protein involved in exopolysaccharide biosynthesis K16554 - - 0.00000000000009921 79.0
HFD2_k127_331613_6 COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family - - - 0.00001472 57.0
HFD2_k127_331613_7 polyketide synthase - - - 0.0001228 54.0
HFD2_k127_3320925_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 3.766e-212 670.0
HFD2_k127_3320925_1 elongation factor G K02355 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 541.0
HFD2_k127_3320925_2 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 304.0
HFD2_k127_3320925_3 Isocitrate isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000003599 167.0
HFD2_k127_3332036_0 PFAM Zinc carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 331.0
HFD2_k127_3332036_1 PFAM glycosyl transferase family 39 - - - 0.00000002305 66.0
HFD2_k127_3333808_0 Competence-damaged protein K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 299.0
HFD2_k127_3333808_1 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000512 90.0
HFD2_k127_3334879_0 ATP-dependent DNA helicase activity K01144,K07464,K16898 - 3.1.11.5,3.1.12.1,3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 363.0
HFD2_k127_334506_0 negative regulation of protein lipidation K19294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 612.0
HFD2_k127_334506_1 Glycosyl transferase family 21 K00786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009229 266.0
HFD2_k127_334506_2 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000005835 164.0
HFD2_k127_334506_3 deoxyhypusine monooxygenase activity - - - 0.000000000000005253 87.0
HFD2_k127_334506_4 Tetratricopeptide repeat - - - 0.0000000001746 74.0
HFD2_k127_3347792_0 Peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 556.0
HFD2_k127_3347792_1 endonuclease activity K07451 - - 0.00000000000000000000000000000000000000000000000002181 195.0
HFD2_k127_3347792_2 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000009758 105.0
HFD2_k127_3347792_3 - - - - 0.000000000001072 77.0
HFD2_k127_3347792_4 nuclease subunit A K16898 - 3.6.4.12 0.00000001309 63.0
HFD2_k127_3347792_5 RING finger protein - - - 0.0000001377 64.0
HFD2_k127_3347792_6 anaphase-promoting complex binding - - - 0.0000002405 63.0
HFD2_k127_3354872_0 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000002463 196.0
HFD2_k127_3354872_1 bacterial-type flagellum-dependent cell motility K01119,K06113,K12685,K20276 - 3.1.3.6,3.1.4.16,3.2.1.99 0.0000000000781 76.0
HFD2_k127_336475_0 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 308.0
HFD2_k127_336475_1 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.000000000000000000001947 95.0
HFD2_k127_3364996_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 425.0
HFD2_k127_3364996_1 PFAM PTS system mannose fructose sorbose family IID component K02796 - - 0.00000000000000000000000000000008066 137.0
HFD2_k127_3364996_2 Phosphotransferase System K11189 - - 0.00000000000000000000002162 101.0
HFD2_k127_3389417_0 cAMP biosynthetic process - - - 0.0000000000000000000000000001238 129.0
HFD2_k127_3389417_1 Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) K07337,K21008 GO:0000270,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0019899,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043085,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044093,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.00061 51.0
HFD2_k127_3402856_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007962 377.0
HFD2_k127_3402856_1 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 300.0
HFD2_k127_3408947_0 Pyridine nucleotide-disulphide oxidoreductase K00529 - 1.18.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 608.0
HFD2_k127_3408947_1 P-loop ATPase protein family K06958,K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 531.0
HFD2_k127_3408947_10 - - - - 0.0000000000000000000000000000000000000000000009965 176.0
HFD2_k127_3408947_11 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000004041 160.0
HFD2_k127_3408947_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000002583 63.0
HFD2_k127_3408947_13 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0008534,GO:0009987,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.0001063 47.0
HFD2_k127_3408947_14 Spore coat protein SP87 - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0012505,GO:0030133,GO:0030312,GO:0031160,GO:0031410,GO:0031982,GO:0043226,GO:0043227,GO:0043229,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097708 - 0.0008917 49.0
HFD2_k127_3408947_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 376.0
HFD2_k127_3408947_3 Amino acid permease family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 370.0
HFD2_k127_3408947_4 pectinesterase activity K10297,K15923,K18197,K19615 - 3.2.1.51,4.2.2.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002315 295.0
HFD2_k127_3408947_5 Nucleotidyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000003279 218.0
HFD2_k127_3408947_6 - - - - 0.0000000000000000000000000000000000000000000000000000001917 207.0
HFD2_k127_3408947_7 SMART Integrin alpha beta-propellor repeat protein - - - 0.0000000000000000000000000000000000000000000000000000006788 218.0
HFD2_k127_3408947_8 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000003803 200.0
HFD2_k127_3408947_9 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000002385 179.0
HFD2_k127_3410219_0 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 508.0
HFD2_k127_3410219_1 PFAM HypF finger K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 508.0
HFD2_k127_3410219_2 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 395.0
HFD2_k127_3410219_3 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.0000000000000000000001932 101.0
HFD2_k127_3410219_4 nickel cation binding K04651 - - 0.000000003071 65.0
HFD2_k127_344485_0 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000007782 89.0
HFD2_k127_344485_1 endonuclease activity K07451 - - 0.000000008572 68.0
HFD2_k127_345709_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 417.0
HFD2_k127_345709_1 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 383.0
HFD2_k127_345709_2 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004989 287.0
HFD2_k127_345709_3 Cation transport regulator - - - 0.0000000000000000000000000000000000000000000000001095 185.0
HFD2_k127_345709_4 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K00851,K00852,K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,2.7.1.15,5.3.1.6 0.0000000000000000000000000000000000000000000002404 171.0
HFD2_k127_345709_5 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000006356 141.0
HFD2_k127_345709_6 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.00000000000000000002505 92.0
HFD2_k127_3464949_0 Zn_pept - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 572.0
HFD2_k127_3464949_1 Zn_pept - - - 0.000000000000000000000004512 110.0
HFD2_k127_3466908_0 COG0553 Superfamily II DNA RNA - - - 1.611e-270 871.0
HFD2_k127_3466908_1 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003727,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010468,GO:0010501,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019439,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0032268,GO:0032270,GO:0033554,GO:0033592,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034655,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043170,GO:0043487,GO:0043488,GO:0043489,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045934,GO:0046483,GO:0046700,GO:0048255,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070035,GO:0070417,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097617,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902369,GO:1902373,GO:1903311,GO:1903312,GO:2000112 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 481.0
HFD2_k127_3466908_2 Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 454.0
HFD2_k127_3472537_0 siderophore transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000009961 248.0
HFD2_k127_3472537_1 hydrolase, family 65, central catalytic - - - 0.00000001023 67.0
HFD2_k127_3474397_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 529.0
HFD2_k127_3474397_1 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000002285 191.0
HFD2_k127_3474397_2 Riboflavin synthase alpha chain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000007808 171.0
HFD2_k127_3475269_0 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 498.0
HFD2_k127_3475269_1 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 395.0
HFD2_k127_3475269_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 319.0
HFD2_k127_3475269_3 outer membrane autotransporter barrel - - - 0.0005096 49.0
HFD2_k127_3481582_0 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 312.0
HFD2_k127_3486132_0 PFAM PhoH family protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 336.0
HFD2_k127_3486132_1 7TM receptor with intracellular HD hydrolase K07037 - - 0.0000003904 62.0
HFD2_k127_348669_0 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000008399 175.0
HFD2_k127_348669_1 Protein of unknown function (DUF3467) - - - 0.00000000000000000000000000000007783 128.0
HFD2_k127_348669_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000002809 108.0
HFD2_k127_348669_3 PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain K01840 - 5.4.2.8 0.00000003393 57.0
HFD2_k127_348669_4 - - - - 0.0002677 46.0
HFD2_k127_3513706_0 AAA domain K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 409.0
HFD2_k127_3513706_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 314.0
HFD2_k127_3513706_2 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000001152 228.0
HFD2_k127_3513706_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000005793 227.0
HFD2_k127_3513706_4 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000008026 201.0
HFD2_k127_3513706_5 Heparinase II/III N-terminus - - - 0.00000000000002858 85.0
HFD2_k127_3518805_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000158 131.0
HFD2_k127_3518805_1 Domain of unknown function (DUF4382) - - - 0.000000000000000000000005926 113.0
HFD2_k127_3518805_2 Tetratricopeptide repeat - - - 0.0000000165 65.0
HFD2_k127_3518805_3 1,4-alpha-glucan branching enzyme activity K00700 - 2.4.1.18 0.000008682 53.0
HFD2_k127_3523730_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 1.525e-201 634.0
HFD2_k127_3523730_1 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000005192 250.0
HFD2_k127_3523730_2 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000002368 123.0
HFD2_k127_3523730_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000004533 108.0
HFD2_k127_3523730_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000005078 79.0
HFD2_k127_3528940_0 COGs COG0160 4-aminobutyrate aminotransferase and related aminotransferase K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 511.0
HFD2_k127_3528940_1 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 469.0
HFD2_k127_3528940_2 phosphatidate phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 434.0
HFD2_k127_3528940_3 peptidase activity K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 352.0
HFD2_k127_3528940_4 N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000001098 201.0
HFD2_k127_3528940_5 Protein of unknown function (DUF1579) - - - 0.0000000000000000000000002276 121.0
HFD2_k127_3528940_6 - - - - 0.00000000000000000002916 96.0
HFD2_k127_3528940_7 RNA polymerase sigma factor K03088 - - 0.0000000000000000005013 95.0
HFD2_k127_3528940_8 - - - - 0.0000000000000002976 81.0
HFD2_k127_3564859_0 imidazolonepropionase activity K01443 - 3.5.1.25 3.387e-244 788.0
HFD2_k127_3564859_1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005845 274.0
HFD2_k127_3564859_2 - - - - 0.0000000000000000000000002606 108.0
HFD2_k127_3564859_4 - - - - 0.0000001167 60.0
HFD2_k127_3564859_5 High confidence in function and specificity - - - 0.000001783 52.0
HFD2_k127_3564859_6 Amidohydrolase family - - - 0.0004888 47.0
HFD2_k127_356494_0 Pfam SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 342.0
HFD2_k127_356494_1 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000000000000000223 178.0
HFD2_k127_3570190_0 ABC transporter K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 412.0
HFD2_k127_3570190_1 PFAM Basic membrane lipoprotein K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 369.0
HFD2_k127_3570190_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 361.0
HFD2_k127_3570190_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004095 290.0
HFD2_k127_3570190_4 PFAM Branched-chain amino acid transport system permease component K02057 - - 0.000000000000000000000000000000003094 146.0
HFD2_k127_3583384_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000003197 112.0
HFD2_k127_3583384_1 Glycosyltransferase like family 2 - - - 0.000000000000005486 76.0
HFD2_k127_3602818_0 PFAM glycosyl transferase family 35 K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 597.0
HFD2_k127_3602818_1 RNA polymerase recycling family C-terminal K03580 - - 0.00000000000000000000000000000000000000000000000000000000000000000007211 254.0
HFD2_k127_3602818_2 PIN domain - - - 0.0000000000000000000000001922 109.0
HFD2_k127_3603900_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 572.0
HFD2_k127_3603900_1 PFAM Cytochrome b b6 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 572.0
HFD2_k127_3603900_2 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.00000000000000000000000000000000000000000000000000000000000000000001002 242.0
HFD2_k127_3603900_3 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000001123 120.0
HFD2_k127_3603900_4 Cytochrome c - - - 0.000000000000000000006441 97.0
HFD2_k127_3609984_0 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 347.0
HFD2_k127_3609984_1 Polysaccharide biosynthesis protein K17947 - 5.1.3.25 0.000000000000000000000000000000000000000000104 165.0
HFD2_k127_3633379_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 7.463e-235 736.0
HFD2_k127_3634495_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 567.0
HFD2_k127_3634495_1 Peptidase family M54 K06974 - - 0.000000000000000000000000000000000000000000000000000333 190.0
HFD2_k127_3634495_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000001378 109.0
HFD2_k127_3654093_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 2.41e-231 741.0
HFD2_k127_3654093_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 485.0
HFD2_k127_3654093_2 Domain of unknown function (DUF305) - - - 0.000000000000000000000000000000000000000000000001067 182.0
HFD2_k127_3654093_3 - - - - 0.00000000000000000000000000000000000003425 153.0
HFD2_k127_3654093_4 Cupredoxin-like domain - - - 0.00000000000000000000000001177 124.0
HFD2_k127_3654093_5 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000009194 83.0
HFD2_k127_3658971_0 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000008543 253.0
HFD2_k127_3658971_1 PTS system sorbose-specific iic component K02795 - - 0.00001059 56.0
HFD2_k127_3660072_0 DNA ligase K01971 - 6.5.1.1 1.226e-241 772.0
HFD2_k127_3660072_1 Belongs to the UPF0337 (CsbD) family - - - 0.000000000000000004399 89.0
HFD2_k127_366098_0 L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp K01876 - 6.1.1.12 2.757e-198 633.0
HFD2_k127_366098_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000006072 68.0
HFD2_k127_3664483_0 Beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 316.0
HFD2_k127_3664483_1 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001287 295.0
HFD2_k127_3664483_2 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000003269 199.0
HFD2_k127_3664483_3 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000001633 154.0
HFD2_k127_3664483_4 Serine acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000003031 142.0
HFD2_k127_3664483_5 transferase activity, transferring glycosyl groups K20922 - - 0.0000000000000000000000001329 118.0
HFD2_k127_3664483_6 lysyltransferase activity K07027 - - 0.00000000000000004124 93.0
HFD2_k127_3667982_0 PFAM fumarate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000767 376.0
HFD2_k127_3667982_1 cellulose binding - - - 0.000000000000005434 84.0
HFD2_k127_3667982_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000005551 69.0
HFD2_k127_3667982_3 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000002365 59.0
HFD2_k127_3672348_0 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 382.0
HFD2_k127_3672348_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 355.0
HFD2_k127_3672348_2 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002867 256.0
HFD2_k127_3672348_3 PQQ-like domain K12132 - 2.7.11.1 0.000000000000000000003675 107.0
HFD2_k127_3672348_4 PKD domain - - - 0.000000000002021 80.0
HFD2_k127_367521_0 PFAM Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005536 254.0
HFD2_k127_367521_1 - - - - 0.00000000000000000000000000006935 130.0
HFD2_k127_367521_2 Belongs to the peptidase S8 family - - - 0.0000000000000000000000001533 121.0
HFD2_k127_3676315_0 ABC-type transport system involved in Fe-S cluster assembly, permease component K09014 - - 7.989e-276 862.0
HFD2_k127_3676315_1 H( )-stimulated, divalent metal cation uptake system K03322 - - 2.827e-207 665.0
HFD2_k127_3676315_2 ABC transporter K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003749 258.0
HFD2_k127_3676315_3 transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000000000000000003343 146.0
HFD2_k127_3676315_4 iron dependent repressor K03709 - - 0.0000000000000000000000000000000001415 136.0
HFD2_k127_368919_0 PFAM Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 358.0
HFD2_k127_368919_1 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000003959 216.0
HFD2_k127_368919_2 SCO1/SenC K07152,K08976 - - 0.00000000000000000000000000000000000001937 149.0
HFD2_k127_368919_3 SCO1/SenC K07152 - - 0.0000000000000000000000000000000003058 141.0
HFD2_k127_368919_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.0000000000000000001999 96.0
HFD2_k127_3698457_0 Divergent polysaccharide deacetylase K09798 - - 0.0000000000000000000003352 109.0
HFD2_k127_3700431_0 Phospholipase A1 K01058 - 3.1.1.32,3.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 299.0
HFD2_k127_3700431_1 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001312 251.0
HFD2_k127_3703751_0 PFAM helicase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001568 244.0
HFD2_k127_3703751_1 - - - - 0.00000000002747 75.0
HFD2_k127_3713231_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. K02584 - - 0.00000000000000000000000000000000000000000000000000000000004619 222.0
HFD2_k127_3713231_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000006085 122.0
HFD2_k127_3729864_0 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 9.159e-286 885.0
HFD2_k127_3732538_0 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000006186 207.0
HFD2_k127_3732538_1 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000002867 100.0
HFD2_k127_3732538_2 - - - - 0.000000000000004533 79.0
HFD2_k127_3735514_0 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000001379 85.0
HFD2_k127_3741992_0 CHAT domain - - - 0.00000000000000000000000000000000001145 149.0
HFD2_k127_3745585_0 SMART Tetratricopeptide domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 400.0
HFD2_k127_3745585_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 358.0
HFD2_k127_3745585_2 Metallopeptidase family M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006561 313.0
HFD2_k127_3745585_3 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000004632 246.0
HFD2_k127_3745585_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0000988,GO:0000990,GO:0002791,GO:0003674,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032879,GO:0032880,GO:0043254,GO:0044087,GO:0044419,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051223,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070201,GO:0080090,GO:0090087,GO:0140110,GO:1903506,GO:1903530,GO:2000112,GO:2000142,GO:2001141 - 0.000000001381 67.0
HFD2_k127_3756263_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000008029 74.0
HFD2_k127_3763693_0 Peptidase family C25 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 424.0
HFD2_k127_3763693_1 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000006068 89.0
HFD2_k127_3763693_2 extracellular matrix structural constituent - - - 0.0000000000003059 85.0
HFD2_k127_3768833_0 Tricorn protease homolog K08676 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004918 289.0
HFD2_k127_3773693_0 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000004355 222.0
HFD2_k127_3773693_1 Capsular exopolysaccharide family - - - 0.000000000000000000000000000000003571 142.0
HFD2_k127_3773693_2 cellulase activity K01081,K01179,K06931 - 3.1.3.5,3.2.1.4 0.000001925 58.0
HFD2_k127_3773693_3 Chain length determinant protein - - - 0.00003571 57.0
HFD2_k127_377817_0 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000167 241.0
HFD2_k127_377817_1 Belongs to the peptidase S8 family K13276 - - 0.000000000000000000000000000000000000000000000000000000009151 229.0
HFD2_k127_377817_2 PKD domain - - - 0.0000000000000000000000000000000000000009566 171.0
HFD2_k127_377817_3 cellulose binding - - - 0.0000000000000000000000000000001465 146.0
HFD2_k127_377817_4 Parallel beta-helix repeats - - - 0.0000000000000000000000000000003341 145.0
HFD2_k127_3785925_0 Aldehyde dehydrogenase family K04021 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 496.0
HFD2_k127_3785925_1 PFAM BMC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 298.0
HFD2_k127_3785925_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000002058 229.0
HFD2_k127_3785925_3 BMC K04027 - - 0.0000000000000000000000000000000000001032 143.0
HFD2_k127_3785925_4 Ethanolamine utilization protein EutN K04028 - - 0.0000000000000002952 81.0
HFD2_k127_3785925_5 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0000003963 57.0
HFD2_k127_3799059_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003261 284.0
HFD2_k127_3799059_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000003467 175.0
HFD2_k127_3799059_2 PFAM outer membrane efflux protein - - - 0.0000000000000000001329 103.0
HFD2_k127_3799059_3 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000002317 84.0
HFD2_k127_3819026_0 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.000000000000000000000000000000001145 142.0
HFD2_k127_3819026_1 Belongs to the peptidase M10A family K07761,K07999 GO:0001101,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009628,GO:0009651,GO:0009719,GO:0009725,GO:0009753,GO:0010033,GO:0010035,GO:0010038,GO:0016020,GO:0016787,GO:0019538,GO:0031224,GO:0031225,GO:0032502,GO:0040007,GO:0042221,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046686,GO:0048519,GO:0048580,GO:0048583,GO:0048589,GO:0048831,GO:0050789,GO:0050793,GO:0050896,GO:0051093,GO:0051239,GO:0051241,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080186,GO:0140096,GO:1900055,GO:1900056,GO:1901564,GO:1901700,GO:1905622,GO:2000024,GO:2000026,GO:2000028,GO:2000241 - 0.0000002756 63.0
HFD2_k127_3819026_2 Fibronectin type III domain - - - 0.00001064 57.0
HFD2_k127_382319_0 O-methyltransferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003362 256.0
HFD2_k127_382319_1 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000004564 212.0
HFD2_k127_382319_2 - - - - 0.00000000000000000000000000000000000000000000000000000922 203.0
HFD2_k127_382319_3 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000001116 87.0
HFD2_k127_382319_4 Belongs to the ClpA ClpB family K03696 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 0.0000005826 61.0
HFD2_k127_382319_5 AcrB/AcrD/AcrF family K03296,K18138 - - 0.000686 44.0
HFD2_k127_3846143_0 FAD binding domain K00103,K00279 - 1.1.3.8,1.5.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008118 344.0
HFD2_k127_3846143_1 Penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000006227 137.0
HFD2_k127_3866008_0 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 351.0
HFD2_k127_3875251_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 2.709e-269 841.0
HFD2_k127_3875251_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840 - 5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009181 342.0
HFD2_k127_3875251_2 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000002674 164.0
HFD2_k127_3875251_3 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000006683 149.0
HFD2_k127_3875251_4 phosphoglucosamine mutase activity K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.000000009335 58.0
HFD2_k127_3875251_5 - - - - 0.00001778 53.0
HFD2_k127_3887823_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006122 282.0
HFD2_k127_3887823_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.000000000000000000000000000000000000000000000000000000000000000001338 233.0
HFD2_k127_3887823_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions - - - 0.00000000000000000000002047 103.0
HFD2_k127_3887823_3 Propeptide_C25 - - - 0.0000000000003136 83.0
HFD2_k127_3887823_4 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.000001045 59.0
HFD2_k127_3902987_0 - - - - 0.0000000000000000000000000000000000000003129 156.0
HFD2_k127_3902987_1 peptidyl-tyrosine sulfation - - - 0.00000001718 68.0
HFD2_k127_3904882_0 N-acetylglucosaminylinositol deacetylase activity K22136 - - 9.8e-247 792.0
HFD2_k127_3905396_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 3.993e-250 788.0
HFD2_k127_3905396_1 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.0000042 61.0
HFD2_k127_3914393_0 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008204 395.0
HFD2_k127_3914393_1 CHAT domain - - - 0.0000000000006365 74.0
HFD2_k127_3915028_0 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003379 276.0
HFD2_k127_3915028_1 5TM C-terminal transporter carbon starvation CstA K06200 - - 0.000000000000000000000000000000000000000128 156.0
HFD2_k127_3915028_2 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000832 122.0
HFD2_k127_3915028_3 6-phosphogluconolactonase activity - - - 0.00000000000000000000000001519 121.0
HFD2_k127_3928735_0 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 585.0
HFD2_k127_3928735_1 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008161 374.0
HFD2_k127_3928735_2 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000000000000001221 207.0
HFD2_k127_3928735_3 metal-sulfur cluster biosynthetic enzyme K02612 - - 0.0000000000000000000000000000000003425 139.0
HFD2_k127_3928735_4 amine dehydrogenase activity - - - 0.00000000004031 74.0
HFD2_k127_3931522_0 cellulose binding - - - 3.407e-263 837.0
HFD2_k127_3931522_1 - - - - 0.00000006549 65.0
HFD2_k127_3931522_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00001376 51.0
HFD2_k127_3941930_0 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 465.0
HFD2_k127_3941930_1 region 4 type 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001152 255.0
HFD2_k127_3941930_2 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000000000000000000000000000000008541 205.0
HFD2_k127_3941930_3 - - - - 0.00000000000000000000006138 105.0
HFD2_k127_3941930_4 antisigma factor binding - - - 0.00000008485 64.0
HFD2_k127_3945007_0 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005664 486.0
HFD2_k127_3945007_1 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002609 245.0
HFD2_k127_3945007_2 Cytochrome c - - - 0.000000000000002318 83.0
HFD2_k127_3968392_0 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 444.0
HFD2_k127_3968392_1 Tetratricopeptide repeat - - - 0.000000000000394 84.0
HFD2_k127_3988195_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000003123 113.0
HFD2_k127_3988195_1 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000001102 96.0
HFD2_k127_400768_0 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 9.625e-251 800.0
HFD2_k127_400768_1 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 381.0
HFD2_k127_400768_2 Porphobilinogen deaminase, dipyromethane cofactor binding domain K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004248 275.0
HFD2_k127_400768_3 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000005408 156.0
HFD2_k127_400768_4 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000004997 151.0
HFD2_k127_400768_5 zinc-ribbon domain - - - 0.00000007101 63.0
HFD2_k127_400816_0 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000003814 184.0
HFD2_k127_400816_1 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000001507 163.0
HFD2_k127_400816_2 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000002782 161.0
HFD2_k127_400816_3 Putative zinc-finger - - - 0.0000005483 56.0
HFD2_k127_4013433_0 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004702 350.0
HFD2_k127_4013433_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 323.0
HFD2_k127_4013433_2 ABC transporter K02003 - - 0.0000000000000000000000000000001328 124.0
HFD2_k127_4020071_0 Polysaccharide lyase family 4, domain II - - - 0.00000000000000000000000000000000000000000000882 169.0
HFD2_k127_4020071_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000788 149.0
HFD2_k127_4020071_2 Pas domain - - - 0.000000000000000000000000006119 119.0
HFD2_k127_4020071_3 UvrD/REP helicase N-terminal domain - - - 0.00000000000000001473 89.0
HFD2_k127_4020071_4 NAD(P)-binding Rossmann-like domain - - - 0.0000000000007907 70.0
HFD2_k127_4071691_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 368.0
HFD2_k127_4071691_1 iron ion homeostasis K03709,K04758 - - 0.0000000000000000000000000000000000000000002059 171.0
HFD2_k127_4071691_2 Transcriptional regulator - - - 0.00000000000000000000000000002775 123.0
HFD2_k127_4071691_3 Radical SAM K01012 - 2.8.1.6 0.000000000000000005241 98.0
HFD2_k127_4074492_0 aconitate hydratase K01681 - 4.2.1.3 1.2e-291 907.0
HFD2_k127_4074492_1 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 0.000000000000000000000000000000000000000000000000001993 195.0
HFD2_k127_4074492_2 - - - - 0.000000000000000000136 104.0
HFD2_k127_4074492_3 Membrane - - - 0.0000004926 57.0
HFD2_k127_4074492_4 NB-ARC domain - - - 0.00001874 57.0
HFD2_k127_4075_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.809e-251 789.0
HFD2_k127_4075_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000001382 238.0
HFD2_k127_4075_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000001852 180.0
HFD2_k127_4075_4 - - - - 0.000005684 57.0
HFD2_k127_4085347_0 synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 295.0
HFD2_k127_4085347_1 Phosphomethylpyrimidine kinase K00941,K14153 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000009819 52.0
HFD2_k127_4095713_0 PglZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006319 560.0
HFD2_k127_4095713_1 ATPases associated with a variety of cellular activities K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 399.0
HFD2_k127_4095713_10 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.0000000002075 70.0
HFD2_k127_4095713_2 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 397.0
HFD2_k127_4095713_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 352.0
HFD2_k127_4095713_4 Transcriptional regulator sugar kinase K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000005748 196.0
HFD2_k127_4095713_5 Belongs to the 5'-nucleotidase family K01119 - 3.1.3.6,3.1.4.16 0.00000000000000000000000000000001708 141.0
HFD2_k127_4095713_6 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000000001446 128.0
HFD2_k127_4095713_7 5'-nucleotidase - - - 0.0000000000000000000000000321 122.0
HFD2_k127_4095713_8 Glycoprotease family K01409,K14742 - 2.3.1.234 0.00000000000000000000001307 109.0
HFD2_k127_4095713_9 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000004461 106.0
HFD2_k127_4104016_0 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 407.0
HFD2_k127_4104016_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000002119 179.0
HFD2_k127_4104016_2 Domain of unknown function (DUF4150) - - - 0.000000000000000000000000000000007785 137.0
HFD2_k127_4104016_3 PFAM pentapeptide repeat protein - - - 0.00000000000000000000000001623 126.0
HFD2_k127_411308_0 heme-binding sites - - - 0.0000000000000000000000000376 124.0
HFD2_k127_411308_1 Integrase core domain - - - 0.000000000000000000000005537 103.0
HFD2_k127_4164333_0 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002593 282.0
HFD2_k127_4164333_1 Belongs to the peptidase S8 family K17734 - - 0.0000000000000000000000001907 123.0
HFD2_k127_4164333_2 PFAM Aminotransferase class I and II K05825 - - 0.00000000001505 67.0
HFD2_k127_4164333_3 cellulose binding - - - 0.0000002352 64.0
HFD2_k127_4164831_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 4.7e-213 670.0
HFD2_k127_4164831_1 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.00000000000000000000000000000000000000000000002459 178.0
HFD2_k127_4164831_2 LysR substrate binding domain - - - 0.0000000000000000000000000000000005206 146.0
HFD2_k127_4170284_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008905 409.0
HFD2_k127_4170284_1 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000505 207.0
HFD2_k127_4170284_2 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000002585 202.0
HFD2_k127_4170284_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000008842 171.0
HFD2_k127_4170284_4 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000001126 155.0
HFD2_k127_4170284_5 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000002312 142.0
HFD2_k127_4170284_6 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000004329 74.0
HFD2_k127_4179383_0 Aspartyl protease - - - 0.00000000000000000000000000000000000000004176 167.0
HFD2_k127_4179383_1 s1 p1 nuclease - - - 0.00000000000000000000000000000000000009755 154.0
HFD2_k127_4179383_2 PFAM transcriptional regulator PadR family protein - - - 0.0000000000000000000006917 102.0
HFD2_k127_4179383_3 peptidase activity, acting on L-amino acid peptides K01337,K05994,K20276 - 3.4.11.10,3.4.21.50 0.0000000000001291 79.0
HFD2_k127_4179383_4 PDZ domain (Also known as DHR or GLGF) K11749 - - 0.0009024 51.0
HFD2_k127_4181562_0 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 596.0
HFD2_k127_4181562_1 - - - - 0.000000000000000001599 87.0
HFD2_k127_4181562_2 - - - - 0.0000000000000006696 78.0
HFD2_k127_4209962_0 MgtC family K07507 - - 0.00000000000000000000000000000000573 134.0
HFD2_k127_4209962_1 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.000000000000001005 82.0
HFD2_k127_4209962_2 - - - - 0.00000000000001676 76.0
HFD2_k127_4209962_3 NlpC/P60 family K13695 - - 0.000000000194 70.0
HFD2_k127_4209962_4 Domain of Unknown Function (DUF350) K08989 - - 0.0000009332 54.0
HFD2_k127_4209962_5 Anti-anti-sigma regulatory factor - - - 0.00002824 51.0
HFD2_k127_4215873_0 PFAM RimK-like ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 405.0
HFD2_k127_4215873_1 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 385.0
HFD2_k127_4215873_2 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 362.0
HFD2_k127_4215873_3 PFAM RimK domain protein ATP-grasp - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 354.0
HFD2_k127_4215873_4 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000003695 164.0
HFD2_k127_4215873_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000001506 149.0
HFD2_k127_4215873_6 ribonuclease activity - - - 0.000000000000000000000000000000002815 132.0
HFD2_k127_4215873_7 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000000000001714 94.0
HFD2_k127_4215873_8 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000005938 78.0
HFD2_k127_4215873_9 Belongs to the UPF0312 family - - - 0.0000001033 61.0
HFD2_k127_4261850_0 Putative glucoamylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 586.0
HFD2_k127_4261850_1 ABC transporter substrate-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 486.0
HFD2_k127_4261850_2 ABC-type sugar transport systems, permease components K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 378.0
HFD2_k127_4261850_3 ABC-type sugar transport system, permease component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009961 306.0
HFD2_k127_4261850_4 OsmC-like protein - - - 0.00000000000000000000000000000000002078 141.0
HFD2_k127_4261850_5 PFAM Glycoside hydrolase 15-related - - - 0.0000000000000000003589 101.0
HFD2_k127_4266142_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009776 586.0
HFD2_k127_4266142_1 Belongs to the type-B carboxylesterase lipase family K01044,K01049,K01050,K01063,K03927 GO:0000003,GO:0003008,GO:0003674,GO:0003824,GO:0004453,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006629,GO:0006714,GO:0006716,GO:0006719,GO:0006720,GO:0006721,GO:0007275,GO:0007568,GO:0007600,GO:0007610,GO:0007617,GO:0007618,GO:0008150,GO:0008152,GO:0008300,GO:0008340,GO:0009056,GO:0009266,GO:0009581,GO:0009582,GO:0009605,GO:0009628,GO:0009636,GO:0009987,GO:0010033,GO:0010259,GO:0010817,GO:0010876,GO:0016042,GO:0016048,GO:0016107,GO:0016115,GO:0016787,GO:0016788,GO:0019098,GO:0019233,GO:0019915,GO:0019953,GO:0022414,GO:0030534,GO:0032501,GO:0032502,GO:0032504,GO:0033036,GO:0034754,GO:0042221,GO:0042445,GO:0042447,GO:0042493,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0045471,GO:0046677,GO:0046683,GO:0048149,GO:0048609,GO:0048856,GO:0050877,GO:0050896,GO:0050906,GO:0050951,GO:0050961,GO:0050965,GO:0051179,GO:0051235,GO:0051606,GO:0051704,GO:0052689,GO:0060179,GO:0065007,GO:0065008,GO:0071704,GO:0097305,GO:1901575,GO:1901700 3.1.1.1,3.1.1.56,3.1.1.59,3.1.1.7,3.1.1.8,3.1.1.84 0.000000000000003412 77.0
HFD2_k127_4275531_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 433.0
HFD2_k127_4278643_0 Biotin carboxylase C-terminal domain K11263 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.4.14,6.4.1.2,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 442.0
HFD2_k127_4278643_1 Hydroxymethylglutaryl-CoA lyase K01640 GO:0003674,GO:0003824,GO:0004419,GO:0005488,GO:0016829,GO:0016830,GO:0016833,GO:0043167,GO:0043169,GO:0046872 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 342.0
HFD2_k127_4278643_2 enoyl-CoA hydratase K13766,K13779 - 4.2.1.18,4.2.1.57 0.000000000000000000000003076 106.0
HFD2_k127_4278643_3 Carbamoyl-phosphate synthase L chain K01968,K11263 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.000000000000002881 88.0
HFD2_k127_4297586_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 520.0
HFD2_k127_4297586_1 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 502.0
HFD2_k127_4297586_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 392.0
HFD2_k127_4297586_3 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000003995 270.0
HFD2_k127_4297586_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000001595 180.0
HFD2_k127_4297586_5 Outer membrane lipoprotein K05807,K08309 - - 0.000000000000000000000000008565 120.0
HFD2_k127_431375_0 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009549 605.0
HFD2_k127_431375_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 319.0
HFD2_k127_431375_2 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000004015 251.0
HFD2_k127_4319411_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006859 343.0
HFD2_k127_4319411_1 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000001477 250.0
HFD2_k127_4319411_2 - K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000016 247.0
HFD2_k127_4320057_0 Permease YjgP YjgQ family protein K07091,K11720 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000002201 261.0
HFD2_k127_4320057_1 Motility related/secretion protein - - - 0.00000000000000000001939 104.0
HFD2_k127_4330672_0 PFAM peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000000000005207 203.0
HFD2_k127_4330672_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000007911 114.0
HFD2_k127_4330672_2 protein containing caspase domain - - - 0.000000000000533 82.0
HFD2_k127_4347314_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 528.0
HFD2_k127_4347314_1 Belongs to the FBPase class 1 family K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 466.0
HFD2_k127_4347314_2 Hypothetical methyltransferase - - - 0.0000000000000000000000008564 122.0
HFD2_k127_4347314_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000002081 106.0
HFD2_k127_4359131_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000008749 224.0
HFD2_k127_4359131_1 PFAM glycoside hydrolase family 13 domain protein - - - 0.00000000000001721 86.0
HFD2_k127_4359131_2 PFAM glycoside hydrolase family 13 domain protein - - - 0.0000000000002763 70.0
HFD2_k127_4363175_0 Lantibiotic biosynthesis dehydratase C-term K20483 - - 3.102e-236 771.0
HFD2_k127_4363175_1 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 619.0
HFD2_k127_4363175_2 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 569.0
HFD2_k127_4363175_3 Biotin-lipoyl like K02005 - - 0.00000001794 65.0
HFD2_k127_4373924_0 PFAM Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 327.0
HFD2_k127_4374121_0 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000009417 214.0
HFD2_k127_4374121_1 Protein of unknown function (DUF3500) - - - 0.000000000000000000002561 93.0
HFD2_k127_4374121_2 AraC-like ligand binding domain - - - 0.000006472 55.0
HFD2_k127_4379007_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 602.0
HFD2_k127_4379007_1 phosphatidate phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 418.0
HFD2_k127_4379007_2 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 400.0
HFD2_k127_4379007_3 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 408.0
HFD2_k127_4379007_4 anaphase-promoting complex binding - - - 0.0008092 49.0
HFD2_k127_4405426_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 2.24e-289 909.0
HFD2_k127_4405426_1 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 393.0
HFD2_k127_4405426_2 coenzyme F420-1:gamma-L-glutamate ligase activity K19285,K19286 - 1.5.1.38,1.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000761 340.0
HFD2_k127_4405426_3 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000005919 240.0
HFD2_k127_4405426_4 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000001824 225.0
HFD2_k127_4405426_5 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000169 193.0
HFD2_k127_4405426_6 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000146 204.0
HFD2_k127_4405426_7 Domain of unknown function (DUF1858) - - - 0.000000000000000000000000000000000000000505 168.0
HFD2_k127_4405426_8 PFAM CBS domain - - - 0.0000000000000000000000000001336 121.0
HFD2_k127_4405426_9 serine threonine protein kinase K12132 - 2.7.11.1 0.000000001044 63.0
HFD2_k127_44189_0 Carboxypeptidase regulatory-like domain - - - 0.00000000008923 73.0
HFD2_k127_44189_1 Belongs to the glycosyl hydrolase 18 family - - - 0.000000002025 65.0
HFD2_k127_4420738_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 9.038e-319 998.0
HFD2_k127_4420738_1 PFAM Mo-co oxidoreductase dimerisation domain K00387 - 1.8.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 338.0
HFD2_k127_4420738_2 Transcriptional - - - 0.000000000000000000000000000001434 123.0
HFD2_k127_4420738_3 Sigma-70, region 4 K03088 - - 0.000000000000000005397 96.0
HFD2_k127_4420738_4 Parallel beta-helix repeats - - - 0.0000000000000005364 80.0
HFD2_k127_4422128_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000001125 198.0
HFD2_k127_4422128_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000001971 155.0
HFD2_k127_4422128_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0002073 50.0
HFD2_k127_442593_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 400.0
HFD2_k127_442593_1 drug transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 398.0
HFD2_k127_442593_2 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 362.0
HFD2_k127_442593_3 Voltage gated chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005774 361.0
HFD2_k127_442593_4 Belongs to the N-Me-Phe pilin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000719 329.0
HFD2_k127_442593_5 protein trimerization - - - 0.0000000000000000000000000000000000000001701 154.0
HFD2_k127_442593_6 cellulase activity - - - 0.0000000000000001444 94.0
HFD2_k127_4442935_0 chitinase - - - 1.827e-194 633.0
HFD2_k127_444735_0 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000042 135.0
HFD2_k127_444735_1 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000002385 64.0
HFD2_k127_4453906_0 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 327.0
HFD2_k127_4453906_1 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001596 280.0
HFD2_k127_4453906_2 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000204 268.0
HFD2_k127_4453906_3 Stage II sporulation protein K06381 - - 0.000000000000000000000000000001007 136.0
HFD2_k127_4471310_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 427.0
HFD2_k127_4471310_1 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007864 257.0
HFD2_k127_4471310_2 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007141 248.0
HFD2_k127_4471310_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.0000000000000000000000000000000000000000000000000000000001696 205.0
HFD2_k127_4471310_4 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000001235 183.0
HFD2_k127_4471310_5 addiction module antidote protein, CC2985 family - - - 0.000000000000000000000000000000000008422 142.0
HFD2_k127_4471310_6 Protein of unknown function (DUF3303) - - - 0.0000000000000000000000000000000000213 139.0
HFD2_k127_4471310_7 Membrane - - - 0.0000000000000000000000000006521 121.0
HFD2_k127_4483249_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 365.0
HFD2_k127_4483249_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000001407 199.0
HFD2_k127_4483249_10 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000001528 84.0
HFD2_k127_4483249_11 UbiA prenyltransferase family - - - 0.0000000000007459 69.0
HFD2_k127_4483249_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000757 181.0
HFD2_k127_4483249_3 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000001626 152.0
HFD2_k127_4483249_4 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000002132 156.0
HFD2_k127_4483249_5 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000001404 134.0
HFD2_k127_4483249_6 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000002235 135.0
HFD2_k127_4483249_7 Could be involved in septation K06412 - - 0.00000000000000000000004124 101.0
HFD2_k127_4483249_8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000004305 94.0
HFD2_k127_4483249_9 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000004672 98.0
HFD2_k127_4484487_0 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 509.0
HFD2_k127_4484487_1 - - - - 0.0000005486 57.0
HFD2_k127_4491096_0 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 475.0
HFD2_k127_4491096_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000008566 233.0
HFD2_k127_4511210_0 phosphorelay signal transduction system K02481,K07713,K07714 - - 1.833e-207 652.0
HFD2_k127_4511210_1 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000005705 145.0
HFD2_k127_4511210_2 response regulator K10943 - - 0.000000000000000000000000000006307 133.0
HFD2_k127_4516647_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 593.0
HFD2_k127_4516647_1 Cytochrome b/b6/petB K03891 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001246 268.0
HFD2_k127_4516647_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000006925 138.0
HFD2_k127_4516647_3 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000004624 114.0
HFD2_k127_451693_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K18307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 416.0
HFD2_k127_451693_1 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000008219 210.0
HFD2_k127_451795_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 552.0
HFD2_k127_451795_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000009563 120.0
HFD2_k127_4521870_0 PFAM NAD dependent epimerase dehydratase family K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 394.0
HFD2_k127_4521870_1 Glycosyl transferase family group 2 K07011 - - 0.000000000000000000000000000000000000001376 170.0
HFD2_k127_4521870_2 extracellular polysaccharide biosynthetic process K01153,K05789,K07011,K16554 - 3.1.21.3 0.00000000000000000000000000000000000004992 158.0
HFD2_k127_4521870_3 Glycosyl transferases group 1 K13668 - 2.4.1.346 0.000000000000000000000001436 121.0
HFD2_k127_4521870_4 Glycosyltransferase - - - 0.0000000000000000002199 92.0
HFD2_k127_4521870_5 export protein - - - 0.00000000002089 68.0
HFD2_k127_4529812_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000008748 112.0
HFD2_k127_4529812_1 PhoQ Sensor - - - 0.000000000000000000001057 107.0
HFD2_k127_4529812_2 PFAM blue (type 1) copper domain protein - - - 0.00006128 51.0
HFD2_k127_4551654_0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009649 393.0
HFD2_k127_4551654_1 Transglycosylase K05366 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 398.0
HFD2_k127_4562989_0 PFAM aminotransferase, class I K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 505.0
HFD2_k127_4562989_1 Hydantoinaseoxoprolinase domain protein K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 394.0
HFD2_k127_4562989_2 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000002804 242.0
HFD2_k127_4562989_3 Belongs to the mandelate racemase muconate lactonizing enzyme family K02549 - 4.2.1.113 0.0000000000000000000005214 96.0
HFD2_k127_4576988_0 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000001494 237.0
HFD2_k127_4576988_1 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000003478 127.0
HFD2_k127_4579825_0 intramolecular transferase activity, transferring amino groups K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 523.0
HFD2_k127_4579825_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 336.0
HFD2_k127_4579825_2 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006699 293.0
HFD2_k127_4579825_3 Metal dependent phosphohydrolases with conserved 'HD' motif. K03698 - - 0.000000000000000000000000000000000000000000000000000000000000000000001936 252.0
HFD2_k127_4579825_4 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000379 240.0
HFD2_k127_4579825_5 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000003404 218.0
HFD2_k127_4579825_6 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000897 206.0
HFD2_k127_4579825_7 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000001502 172.0
HFD2_k127_4579825_8 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00003322 54.0
HFD2_k127_4586441_0 Sortilin, neurotensin receptor 3, - - - 0.0 1321.0
HFD2_k127_4586441_1 Oligopeptidase F K08602 - - 3.674e-237 747.0
HFD2_k127_4586441_2 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 464.0
HFD2_k127_4586441_3 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000000000001023 173.0
HFD2_k127_4609108_0 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004357 266.0
HFD2_k127_4609108_1 Belongs to the metal hydrolase YfiT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003986 241.0
HFD2_k127_4609108_2 Methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000001309 177.0
HFD2_k127_4609108_3 PhoD-like phosphatase - - - 0.000000000000000000000000000000000000000117 168.0
HFD2_k127_4648901_0 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000021 224.0
HFD2_k127_4648901_1 Polysaccharide deacetylase K11931 - - 0.000000000000000000000000000001665 130.0
HFD2_k127_4655774_0 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.000000000000000000000000000000000000000000000000000008384 200.0
HFD2_k127_4655774_1 - - - - 0.0000000000000000000004159 104.0
HFD2_k127_466354_0 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 458.0
HFD2_k127_466354_1 PFAM PRC-barrel domain - - - 0.0000000000000000000000000000000001107 138.0
HFD2_k127_466354_2 bacterial OsmY and nodulation domain - - - 0.000000000000000000000002396 117.0
HFD2_k127_466354_3 - - - - 0.0000000000000000000001276 100.0
HFD2_k127_4668677_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 332.0
HFD2_k127_4668677_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000816 316.0
HFD2_k127_4668677_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000001667 201.0
HFD2_k127_4668677_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000004389 122.0
HFD2_k127_4668677_4 peptidyl-tyrosine sulfation - - - 0.0000000000003183 79.0
HFD2_k127_4668677_5 Glycosyl transferase family 41 - - - 0.0000003423 61.0
HFD2_k127_4672795_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000007449 245.0
HFD2_k127_4672795_1 FRG - - - 0.00000000000000000000000000003695 119.0
HFD2_k127_4672795_2 Peptidylprolyl isomerase K01802,K03770 - 5.2.1.8 0.00001069 55.0
HFD2_k127_4682973_0 COG1020 Non-ribosomal peptide synthetase modules and related proteins - - - 0.0 1391.0
HFD2_k127_4687653_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1150.0
HFD2_k127_4687653_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.188e-306 956.0
HFD2_k127_4687653_10 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000000347 71.0
HFD2_k127_4687653_11 Outer membrane efflux protein K15725 - - 0.0000003192 63.0
HFD2_k127_4687653_12 Heavy metal translocating P-type atpase - - - 0.000001728 59.0
HFD2_k127_4687653_2 Putative zinc-binding metallo-peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 441.0
HFD2_k127_4687653_3 ATP-grasp domain K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 345.0
HFD2_k127_4687653_4 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000006145 231.0
HFD2_k127_4687653_5 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000002592 192.0
HFD2_k127_4687653_6 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000001154 142.0
HFD2_k127_4687653_7 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000466 96.0
HFD2_k127_4687653_8 - - - - 0.0000000000009367 76.0
HFD2_k127_4698047_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 420.0
HFD2_k127_4698047_1 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 352.0
HFD2_k127_4698047_2 NeuB family K03856 - 2.5.1.54 0.00000002945 55.0
HFD2_k127_4727817_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 556.0
HFD2_k127_4727817_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 341.0
HFD2_k127_4727817_2 Outer membrane efflux protein - - - 0.000000002898 66.0
HFD2_k127_4742398_0 Surface antigen K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.00000000000000000000000000000000000000000000000002419 201.0
HFD2_k127_4755268_0 Surface antigen K07277 - - 0.00000000004917 68.0
HFD2_k127_4755268_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0003271 54.0
HFD2_k127_4757563_0 Immune inhibitor A peptidase M6 - - - 0.00000000000000000000000000000000000000000000000000000000000004076 244.0
HFD2_k127_4757563_1 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.000000000000000000000000000001441 130.0
HFD2_k127_4757563_2 peptidase activity, acting on L-amino acid peptides K01187,K01448,K07752 - 3.2.1.20,3.4.17.22,3.5.1.28 0.00000000000000000000000003467 127.0
HFD2_k127_476184_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 514.0
HFD2_k127_476184_1 PFAM Alpha beta hydrolase K07019 - - 0.0000000006801 60.0
HFD2_k127_4762222_0 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000009914 185.0
HFD2_k127_4762222_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000001806 139.0
HFD2_k127_4762222_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000001713 90.0
HFD2_k127_47630_0 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001484 281.0
HFD2_k127_47630_1 AAA domain - - - 0.00000000000000000000000000000000000002539 164.0
HFD2_k127_47630_2 Putative ATP-binding cassette K01992 - - 0.00000000000004762 85.0
HFD2_k127_479840_0 PKD domain - - - 0.0000000000000000000000000000000000000000000001096 189.0
HFD2_k127_4803578_0 Aldo/keto reductase family K05882 - 1.1.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007117 385.0
HFD2_k127_4803578_1 2 iron, 2 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 362.0
HFD2_k127_4803578_2 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000004762 215.0
HFD2_k127_4803578_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000005974 97.0
HFD2_k127_4803578_4 aldo keto reductase - - - 0.0000000000001063 71.0
HFD2_k127_4803578_6 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) - - - 0.0000003712 57.0
HFD2_k127_4803578_7 Belongs to the DegT DnrJ EryC1 family K05957 - 2.6.1.50 0.00008589 53.0
HFD2_k127_4810816_0 PFAM Glu Leu Phe Val dehydrogenase , Glu Leu Phe Val dehydrogenase dimerization region K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 318.0
HFD2_k127_4810816_1 Beta-L-arabinofuranosidase, GH127 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001096 271.0
HFD2_k127_4810816_2 Polysaccharide biosynthesis protein - - - 0.000000000000000000001444 102.0
HFD2_k127_4810816_3 Glycosyl transferase 4-like domain - - - 0.00000000000002852 78.0
HFD2_k127_4810816_4 Methicillin resistance protein - - - 0.00000003639 65.0
HFD2_k127_4811039_0 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000001192 200.0
HFD2_k127_4811039_1 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000117 141.0
HFD2_k127_4811039_2 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.0000000000009271 72.0
HFD2_k127_482261_0 Peptidase family C25 - - - 0.000000000000000000000000000000000000000000000000000000000000001716 246.0
HFD2_k127_4827001_0 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000008293 229.0
HFD2_k127_4827001_1 Belongs to the peptidase S8 family K08651,K14743 - 3.4.21.66 0.000000000211 70.0
HFD2_k127_483071_0 Belongs to the peptidase S8 family K08651,K14743 - 3.4.21.66 0.000000000000000000000000000000000000000000006848 176.0
HFD2_k127_483071_1 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000749 133.0
HFD2_k127_483071_2 oligosaccharyl transferase activity - - - 0.000000000006294 72.0
HFD2_k127_4835396_0 - K20326 - - 0.0000000001076 70.0
HFD2_k127_4835396_1 cellulase activity - - - 0.0001866 53.0
HFD2_k127_4842032_0 response regulator K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001057 265.0
HFD2_k127_4842032_1 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000004603 194.0
HFD2_k127_4842032_2 - - - - 0.000000000000000000000000000000008433 150.0
HFD2_k127_4850999_0 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000001451 209.0
HFD2_k127_4850999_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000007015 124.0
HFD2_k127_4855271_1 Fibronectin type 3 domain K05366 GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 0.00000008658 59.0
HFD2_k127_4859037_0 Nad-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 357.0
HFD2_k127_4859037_1 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000005286 174.0
HFD2_k127_4859037_2 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.0000001547 53.0
HFD2_k127_4859123_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007504 335.0
HFD2_k127_4859123_1 Sugar-specific transcriptional regulator TrmB - - - 0.00006128 51.0
HFD2_k127_4876841_0 PFAM Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000004833 252.0
HFD2_k127_4876841_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000002358 64.0
HFD2_k127_4899802_0 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 348.0
HFD2_k127_4899802_1 DNA-templated transcription, initiation K03088 - - 0.0000000000002788 75.0
HFD2_k127_4919669_0 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003079 265.0
HFD2_k127_4919669_1 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000914 169.0
HFD2_k127_4919669_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000009112 96.0
HFD2_k127_4919669_3 Domain of unknown function (DUF4114) - - - 0.000000000000003758 82.0
HFD2_k127_4919669_4 PFAM PspC domain - - - 0.0000000003618 68.0
HFD2_k127_4926237_0 Alanine dehydrogenase/PNT, C-terminal domain K07538 - 1.1.1.368 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 381.0
HFD2_k127_4926237_1 - - - - 0.00000000000000000000000003033 115.0
HFD2_k127_4933049_0 COG4263 Nitrous oxide reductase K00376 - 1.7.2.4 9.235e-221 708.0
HFD2_k127_4933049_1 Domain present in carbohydrate binding proteins and sugar hydrolses K07218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007134 334.0
HFD2_k127_4933049_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000004977 183.0
HFD2_k127_4933049_3 - K19341 - - 0.0000000000000000000000000000007457 129.0
HFD2_k127_4933049_4 Transcriptional regulator - - - 0.0000000000000000000000000004672 119.0
HFD2_k127_4933049_5 lipoprotein involved in nitrous oxide reduction - - - 0.00000000000000000001092 109.0
HFD2_k127_4933049_6 Major facilitator Superfamily K06902 - - 0.0000006133 61.0
HFD2_k127_4937027_0 NUDIX domain K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001161 268.0
HFD2_k127_4942122_0 ATPases associated with a variety of cellular activities K10823,K10824 - 3.6.3.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 402.0
HFD2_k127_4942122_1 Belongs to the ABC transporter superfamily K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 381.0
HFD2_k127_4942122_2 'ABC-type dipeptide oligopeptide nickel transport K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 354.0
HFD2_k127_4942122_3 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008541 330.0
HFD2_k127_4942122_4 Belongs to the peptidase S8 family K08651,K14743 - 3.4.21.66 0.000000000000000000000000000000000000000000002595 181.0
HFD2_k127_4942122_5 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000005819 115.0
HFD2_k127_4943234_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 319.0
HFD2_k127_4943234_1 MutS domain I K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000002684 214.0
HFD2_k127_4943234_2 PFAM GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000007894 177.0
HFD2_k127_4943234_3 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000001084 161.0
HFD2_k127_4943234_4 Belongs to the BshC family K22136 - - 0.0000000000000000000000000000000000000001671 169.0
HFD2_k127_4943234_5 belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000001945 142.0
HFD2_k127_4956550_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 325.0
HFD2_k127_4956550_1 Protein of unknown function (DUF2723) K14340 - - 0.0000000001013 74.0
HFD2_k127_4958380_0 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 610.0
HFD2_k127_4958380_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 474.0
HFD2_k127_4958380_2 Aldo/keto reductase family K16950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 469.0
HFD2_k127_4958380_3 coenzyme F420 hydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 372.0
HFD2_k127_4958380_4 2 iron, 2 sulfur cluster binding K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 358.0
HFD2_k127_4958380_5 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000005133 197.0
HFD2_k127_4958380_6 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000001848 177.0
HFD2_k127_4958380_7 Hydrogenase maturation protease - - - 0.00000000000000000000003195 109.0
HFD2_k127_4958380_8 Belongs to the carbamoyltransferase HypF family K04656 - - 0.00000000000001547 83.0
HFD2_k127_4966702_0 UDP-N-acetylmuramate-L-alanine ligase activity K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 523.0
HFD2_k127_4966702_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 374.0
HFD2_k127_4966702_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003496 284.0
HFD2_k127_4966702_3 cell septum assembly K03589 - - 0.000000000008581 76.0
HFD2_k127_499062_0 MreB/Mbl protein K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 455.0
HFD2_k127_499062_1 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000248 128.0
HFD2_k127_4995756_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 283.0
HFD2_k127_4995756_1 Patatin-like phospholipase K07001 - - 0.000000000000000000003039 98.0
HFD2_k127_5014695_0 isoleucyl-tRNA aminoacylation K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 362.0
HFD2_k127_5014695_1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 353.0
HFD2_k127_5021611_0 MotA TolQ ExbB proton channel K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000004932 201.0
HFD2_k127_5021611_1 - - - - 0.000000000000000000000000000000216 131.0
HFD2_k127_5021611_2 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000003305 115.0
HFD2_k127_5021611_3 TIGRFAM TonB family K03832 - - 0.00000000000000000000000009597 111.0
HFD2_k127_5021611_4 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000001212 101.0
HFD2_k127_5021611_5 - - - - 0.0000000000000000007883 94.0
HFD2_k127_5021611_6 Recombinase zinc beta ribbon domain K06400 - - 0.0000000438 57.0
HFD2_k127_502311_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.953e-269 847.0
HFD2_k127_502311_1 Cytochrome C assembly protein K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 307.0
HFD2_k127_5030183_0 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000002399 206.0
HFD2_k127_5030183_1 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000001848 146.0
HFD2_k127_5030183_2 Uncharacterized conserved protein (DUF2203) - - - 0.0000001375 53.0
HFD2_k127_504832_0 curli production assembly transport component CsgG K04087 - - 0.0000000000000002741 91.0
HFD2_k127_504832_1 peptidoglycan-binding domain-containing protein - - - 0.0004299 52.0
HFD2_k127_5050044_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008459 458.0
HFD2_k127_5050044_1 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 311.0
HFD2_k127_5050044_2 Integral membrane sensor signal transduction histidine kinase K07709,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006677 299.0
HFD2_k127_5050044_3 Ami_3 K01448 - 3.5.1.28 0.000000002084 70.0
HFD2_k127_505636_0 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000003902 176.0
HFD2_k127_505636_1 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.000000000000000000000000000014 122.0
HFD2_k127_505636_2 FR47-like protein K03789 - 2.3.1.128 0.0000000000000000000000004391 111.0
HFD2_k127_505636_3 Protein of unknown function (DUF465) K09794 - - 0.0000003906 55.0
HFD2_k127_5063683_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 454.0
HFD2_k127_5063683_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000001853 260.0
HFD2_k127_5063683_2 transmembrane transport K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000002289 249.0
HFD2_k127_5063683_3 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000003012 196.0
HFD2_k127_5063683_4 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000004711 136.0
HFD2_k127_5063683_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000004103 81.0
HFD2_k127_5063683_7 TIGRFAM filamentous hemagglutinin family N-terminal domain - - - 0.00008471 54.0
HFD2_k127_5064875_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 466.0
HFD2_k127_5064875_1 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001353 277.0
HFD2_k127_5064875_2 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000001008 173.0
HFD2_k127_5066647_0 B12 binding domain K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 338.0
HFD2_k127_5066647_1 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004951 260.0
HFD2_k127_5066647_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000107 55.0
HFD2_k127_5069033_0 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 321.0
HFD2_k127_5069033_1 CHAT domain - - - 0.00000000002672 76.0
HFD2_k127_5069033_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00001372 57.0
HFD2_k127_5069086_0 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 316.0
HFD2_k127_5069086_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002539 266.0
HFD2_k127_5069086_2 UMP kinase activity K09903 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 0.000000000000000000000000000000000006638 140.0
HFD2_k127_5071287_0 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000003376 68.0
HFD2_k127_5071287_1 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000001268 64.0
HFD2_k127_5071287_2 Gram-negative bacterial TonB protein C-terminal - - - 0.0000002704 62.0
HFD2_k127_5071287_3 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00001587 49.0
HFD2_k127_5086280_0 WD40-like Beta Propeller Repeat - - - 3.428e-238 760.0
HFD2_k127_5086280_1 Prolyl oligopeptidase, N-terminal beta-propeller domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009559 619.0
HFD2_k127_5086280_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 542.0
HFD2_k127_5086280_3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000003535 154.0
HFD2_k127_5089364_0 PFAM Surface antigen variable number repeat K07277 - - 0.00000028 63.0
HFD2_k127_5089402_0 Peptidase family M3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 486.0
HFD2_k127_5089402_1 lipolytic protein G-D-S-L family - - - 0.0000000000628 74.0
HFD2_k127_509033_0 Ribosomal protein S1 K02945,K03527,K12132 GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 1.17.7.4,2.7.11.1 4.123e-219 698.0
HFD2_k127_509033_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 365.0
HFD2_k127_509033_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000001689 198.0
HFD2_k127_509033_3 glycosyl transferase family 2 - - - 0.00000000000000000000000000003097 120.0
HFD2_k127_5092805_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009523 293.0
HFD2_k127_5092805_1 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000001615 176.0
HFD2_k127_5092805_2 Histidine kinase K13598 - 2.7.13.3 0.00000000000000000000000000000000000000001406 173.0
HFD2_k127_5092805_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000005572 69.0
HFD2_k127_5107988_0 dehydrogenase e1 component K00164 - 1.2.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 534.0
HFD2_k127_5107988_1 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 319.0
HFD2_k127_5107988_2 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.0000002493 54.0
HFD2_k127_511224_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 487.0
HFD2_k127_511224_1 Carbamoyltransferase C-terminus K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 450.0
HFD2_k127_511224_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000003539 232.0
HFD2_k127_511224_3 - - - - 0.00000000000000000007288 95.0
HFD2_k127_511224_4 - - - - 0.0000000009446 68.0
HFD2_k127_511224_5 - - - - 0.0003484 53.0
HFD2_k127_511928_0 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000004661 240.0
HFD2_k127_511928_1 Pregnancy-associated plasma protein-A - - - 0.00000000000000000000000000000000000000000008109 170.0
HFD2_k127_511928_2 Parallel beta-helix repeats - - - 0.0000000000000000000000000000342 135.0
HFD2_k127_511928_3 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000007317 92.0
HFD2_k127_5121417_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 6.716e-214 688.0
HFD2_k127_5122468_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 377.0
HFD2_k127_5122468_1 protein secretion K09800 - - 0.000000000000002458 86.0
HFD2_k127_5122468_2 amino acid activation for nonribosomal peptide biosynthetic process K06045 - 4.2.1.129,5.4.99.17 0.0000000000002882 80.0
HFD2_k127_512323_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 1.694e-240 784.0
HFD2_k127_512323_1 Domain of unknown function (DUF1772) - - - 0.0000000000000000000000000000000000000002413 159.0
HFD2_k127_5124175_0 COG0515 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000004032 92.0
HFD2_k127_5143932_0 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.000000000000000008297 94.0
HFD2_k127_5144793_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000926 79.0
HFD2_k127_518650_1 PFAM TonB-dependent Receptor Plug - - - 0.000000000000000003523 98.0
HFD2_k127_5188912_0 Carbon starvation protein K06200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 408.0
HFD2_k127_5188912_1 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 351.0
HFD2_k127_5188912_2 Cytochrome C biogenesis protein transmembrane region K06196,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000002082 253.0
HFD2_k127_5188912_3 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001586 263.0
HFD2_k127_5188912_4 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000008521 180.0
HFD2_k127_5188912_5 MoaC family K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000002989 164.0
HFD2_k127_5188912_6 Thioredoxin-like - - - 0.00000000000000000000000000000002534 134.0
HFD2_k127_5195031_0 AAA domain - - - 2.628e-298 968.0
HFD2_k127_5195031_1 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 499.0
HFD2_k127_5195031_2 COG0534 Na -driven multidrug efflux pump K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 414.0
HFD2_k127_5195031_3 Tetratricopeptide repeat - - - 0.0000000000000009216 92.0
HFD2_k127_5195031_4 hydrolase activity, hydrolyzing N-glycosyl compounds - - - 0.000000000001931 74.0
HFD2_k127_5195031_5 Tetratricopeptide repeats - - - 0.0000000607 66.0
HFD2_k127_5195031_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0004341 52.0
HFD2_k127_5199915_0 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000002951 230.0
HFD2_k127_5199915_1 - - - - 0.0000001286 56.0
HFD2_k127_5200984_0 transcription factor binding K02584,K11914 - - 0.000000000000000000000000000000000000000000000000000000000003952 236.0
HFD2_k127_5204178_0 PFAM aldehyde oxidase and xanthine dehydrogenase molybdopterin binding K00256 - 1.3.99.16 1.744e-233 746.0
HFD2_k127_5204178_1 2Fe-2S -binding domain protein K18029 - 1.17.2.1 0.000000000000000000000000000000000000000000000000000000000000005953 218.0
HFD2_k127_5215729_0 coenzyme F390 K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 471.0
HFD2_k127_5215729_1 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 402.0
HFD2_k127_5215729_2 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000629 276.0
HFD2_k127_5215729_3 undecaprenyl-phosphate glucose phosphotransferase activity K03606,K05946,K21303 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016780,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046402,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.187,2.7.8.40 0.00000000000000000000000000000001234 128.0
HFD2_k127_5215729_4 polysaccharide export protein K01991 - - 0.00000000000000000000005525 113.0
HFD2_k127_5215729_5 Polysaccharide biosynthesis protein - - - 0.0000000000000000000001131 109.0
HFD2_k127_5218261_0 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 537.0
HFD2_k127_5218261_1 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 494.0
HFD2_k127_5218261_10 denitrification pathway K02569,K15876 - - 0.00000000000000000000009448 112.0
HFD2_k127_5218261_11 signal-transduction protein with CBS domains - - - 0.0000000000001507 83.0
HFD2_k127_5218261_12 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000002903 73.0
HFD2_k127_5218261_13 metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000845 69.0
HFD2_k127_5218261_14 Cyclic nucleotide-monophosphate binding domain - - - 0.000000002889 69.0
HFD2_k127_5218261_15 cheY-homologous receiver domain - - - 0.00000002 62.0
HFD2_k127_5218261_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 486.0
HFD2_k127_5218261_3 Cytochrome c K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 306.0
HFD2_k127_5218261_4 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 291.0
HFD2_k127_5218261_5 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001954 290.0
HFD2_k127_5218261_6 Cytochrome c554 and c-prime K03620 - - 0.000000000000000000000000000000000000000000000000000000000000705 227.0
HFD2_k127_5218261_7 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000002556 174.0
HFD2_k127_5218261_8 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000105 132.0
HFD2_k127_5218261_9 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.00000000000000000000000003634 112.0
HFD2_k127_5219411_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000769 562.0
HFD2_k127_5219411_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000002018 224.0
HFD2_k127_5219411_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000009598 49.0
HFD2_k127_5229707_0 Putative zinc-finger - - - 0.00000000000000000000000000000000000000000000000000000005504 206.0
HFD2_k127_5229707_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000003954 224.0
HFD2_k127_5229707_2 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000002596 176.0
HFD2_k127_5229707_3 - - - - 0.000001056 61.0
HFD2_k127_5229707_4 ABC transporter C-terminal domain K06158 - - 0.000003599 53.0
HFD2_k127_5233887_0 Transglutaminase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 383.0
HFD2_k127_5233887_1 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 364.0
HFD2_k127_5233887_2 Tail Collar domain - - - 0.0000000000000000000000000000000000000000000000000001171 195.0
HFD2_k127_5233887_3 Phage Tail Collar Domain - - - 0.000000000000000000000000000000000000000000000000006264 188.0
HFD2_k127_5233887_4 PFAM Tail Collar domain protein - - - 0.00000000000000000000000000000000000000000000000002302 183.0
HFD2_k127_5233887_5 negative regulation of growth rate K02599 - - 0.00000000000001764 85.0
HFD2_k127_5233887_6 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.0000000101 65.0
HFD2_k127_5233887_7 PFAM Peptidase M56, BlaR1 - - - 0.000004312 59.0
HFD2_k127_5234933_0 helicase involved in DNA repair and perhaps also replication K02342,K03722 - 2.7.7.7,3.6.4.12 0.0000000000000000000000000000000000000000000000000000003703 211.0
HFD2_k127_5236031_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 484.0
HFD2_k127_5236031_1 endonuclease activity K07451 - - 0.00000000000000000000000004322 115.0
HFD2_k127_5236031_2 Subtilase family - - - 0.00000000000000000005663 95.0
HFD2_k127_5250802_0 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 412.0
HFD2_k127_5252106_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000008487 215.0
HFD2_k127_5252106_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000004335 206.0
HFD2_k127_5257889_0 Penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000000000000000001695 242.0
HFD2_k127_5257889_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.0000000002361 63.0
HFD2_k127_5264290_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008136 499.0
HFD2_k127_5264290_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000003659 152.0
HFD2_k127_5264290_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K00335 - 1.6.5.3 0.00000000000000000000000000000000000002633 156.0
HFD2_k127_5264290_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044464,GO:0050136,GO:0055114,GO:0071944,GO:0098796,GO:1902494 1.6.5.3 0.0000000000000000000000000000000000007913 150.0
HFD2_k127_5264290_4 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000002262 132.0
HFD2_k127_527568_0 beta-galactosidase activity K01224 - 3.2.1.89 4.492e-207 664.0
HFD2_k127_527568_1 beta-galactosidase activity K01224 - 3.2.1.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 578.0
HFD2_k127_527568_2 Glycosyl hydrolase family 1 K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000007789 203.0
HFD2_k127_5301932_0 7TM receptor with intracellular HD hydrolase K07037 - - 0.0000000000000000000000000000000000000000000000000008554 188.0
HFD2_k127_5301932_1 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000005596 184.0
HFD2_k127_5301932_2 SMART CBS domain containing protein - - - 0.0000000000000000000000000000000000004919 156.0
HFD2_k127_5301932_3 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000006616 148.0
HFD2_k127_5301932_4 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000001057 128.0
HFD2_k127_5301932_5 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K07042 - 3.5.4.5 0.00000000000000000000001699 107.0
HFD2_k127_5302853_0 Putative methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 544.0
HFD2_k127_5302853_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 381.0
HFD2_k127_5302853_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008377 359.0
HFD2_k127_5302853_3 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000003594 166.0
HFD2_k127_5302853_4 PFAM cytochrome c assembly protein - - - 0.00000000000000000000000000000000000008313 152.0
HFD2_k127_5302853_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.00000000000000000000000000000000000009867 146.0
HFD2_k127_5302853_6 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000001068 118.0
HFD2_k127_5302853_7 ATP synthesis coupled electron transport K00340,K05576 - 1.6.5.3 0.000000000000000000005233 98.0
HFD2_k127_5307772_0 membrane protein, TerC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 422.0
HFD2_k127_5307772_1 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 303.0
HFD2_k127_5307772_2 PFAM Alpha beta hydrolase K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000208 244.0
HFD2_k127_5307772_3 Transcriptional regulator K03717 - - 0.0000000000000000000000001154 107.0
HFD2_k127_5317790_0 domain protein - - - 0.00000000000000000000000000000000000000000000000000000003336 219.0
HFD2_k127_5321600_0 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 445.0
HFD2_k127_5321600_1 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 339.0
HFD2_k127_5321600_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 0.000000000000000000000000000000000000000000002984 170.0
HFD2_k127_5321600_3 GCN5 family acetyltransferase - - - 0.00000000000000000000000000000000000000836 163.0
HFD2_k127_5330710_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 4.355e-234 735.0
HFD2_k127_5330710_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 492.0
HFD2_k127_5330710_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001727 248.0
HFD2_k127_5330710_3 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000766 198.0
HFD2_k127_5333276_0 S-layer protein - - - 0.0000000004566 69.0
HFD2_k127_5333276_1 Protein of unknown function (DUF2752) - - - 0.00001215 53.0
HFD2_k127_5333276_2 - - - - 0.00003201 52.0
HFD2_k127_5338844_0 Asparaginase K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003807 282.0
HFD2_k127_5338844_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000001085 202.0
HFD2_k127_5338844_2 glycolate biosynthetic process K01091 - 3.1.3.18 0.000000000000000000000000002763 118.0
HFD2_k127_5338844_3 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000001081 108.0
HFD2_k127_5338844_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.000000000000000002933 93.0
HFD2_k127_5339762_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 349.0
HFD2_k127_5339762_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000004984 216.0
HFD2_k127_5339762_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000001826 65.0
HFD2_k127_5365166_0 type ii restriction enzyme K01155 - 3.1.21.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 312.0
HFD2_k127_5367363_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 582.0
HFD2_k127_5370959_0 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.00000000000000000000000000000000000000000000000000000000000005841 226.0
HFD2_k127_5370959_1 Histidine kinase-like ATPase domain K01338,K04757,K06379,K08282,K17752 - 2.7.11.1,3.4.21.53 0.0000000000000000000000000000000000000000000000000000000002257 213.0
HFD2_k127_5370959_2 - - - - 0.0000000000000000000000000000000000000000000005168 177.0
HFD2_k127_5370959_4 PhoQ Sensor - - - 0.000000000002494 72.0
HFD2_k127_5372613_0 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001495 258.0
HFD2_k127_5372613_1 Copper amine oxidase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003806 228.0
HFD2_k127_5372613_2 lipolytic protein G-D-S-L family K11751 - 3.1.3.5,3.6.1.45 0.00000000000000000001116 103.0
HFD2_k127_5372613_3 Methyltransferase - - - 0.0000000000001372 82.0
HFD2_k127_5372613_4 NfeD-like C-terminal, partner-binding - - - 0.000006324 55.0
HFD2_k127_537309_0 MviN-like protein K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 309.0
HFD2_k127_5377479_0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 1.049e-267 844.0
HFD2_k127_5377479_1 PFAM FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 597.0
HFD2_k127_5377479_2 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 455.0
HFD2_k127_5377479_3 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 392.0
HFD2_k127_5377479_4 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000004401 218.0
HFD2_k127_5377479_5 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000001017 97.0
HFD2_k127_5377479_6 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.00002825 57.0
HFD2_k127_5377479_7 Endonuclease/Exonuclease/phosphatase family - - - 0.0008296 49.0
HFD2_k127_5378466_0 - - - - 0.00000001168 69.0
HFD2_k127_5378466_1 Evidence 5 No homology to any previously reported sequences - - - 0.00000005194 60.0
HFD2_k127_5403443_0 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 303.0
HFD2_k127_5403443_1 glycosyl transferase group 1 K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000002562 247.0
HFD2_k127_5403443_2 PFAM OmpA MotB domain protein K03640 - - 0.000000000000000000000000000000141 140.0
HFD2_k127_5403443_3 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000001204 128.0
HFD2_k127_5403443_4 TonB C terminal K03832 - - 0.000000004422 68.0
HFD2_k127_5403443_5 PFAM glycosyl transferase family 9 - - - 0.00000001183 61.0
HFD2_k127_5403443_6 Protein of unknown function (DUF507) - - - 0.0000004506 60.0
HFD2_k127_5403443_7 Protein of unknown function (DUF507) K09804 - - 0.000003562 53.0
HFD2_k127_5405635_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 2.842e-260 811.0
HFD2_k127_5405635_1 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 384.0
HFD2_k127_5405635_2 PFAM Phenylalanine and histidine ammonia-lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000945 362.0
HFD2_k127_5405635_3 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000008873 266.0
HFD2_k127_5405635_4 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000001422 95.0
HFD2_k127_5410397_0 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 417.0
HFD2_k127_5410397_1 ABC transporter, ATP-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001694 246.0
HFD2_k127_5410397_2 Acid phosphatase homologues - - - 0.0000000000000000004425 96.0
HFD2_k127_5419538_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1649.0
HFD2_k127_5419538_1 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 3.681e-223 713.0
HFD2_k127_5419538_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 293.0
HFD2_k127_5419538_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000003035 100.0
HFD2_k127_5419538_4 Cytidylyltransferase family - - - 0.0000000000000000004505 90.0
HFD2_k127_5419538_5 Universal stress protein - - - 0.00000000000007826 74.0
HFD2_k127_5419538_6 Belongs to the ompA family - - - 0.000000000001026 77.0
HFD2_k127_5419538_7 Common central domain of tyrosinase K00505 - 1.14.18.1 0.000009694 57.0
HFD2_k127_5438218_0 phosphorylase K00688 - 2.4.1.1 3.157e-302 949.0
HFD2_k127_5438218_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0000000000000000006697 91.0
HFD2_k127_5438478_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 3.59e-285 886.0
HFD2_k127_5438478_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 411.0
HFD2_k127_5438478_2 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005213 281.0
HFD2_k127_5438478_3 signal sequence binding K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006163 256.0
HFD2_k127_5438478_4 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000001551 243.0
HFD2_k127_5438478_5 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00000000000009511 81.0
HFD2_k127_5438478_6 - - - - 0.0000000000001324 81.0
HFD2_k127_54408_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 301.0
HFD2_k127_54408_1 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.00000000000000000000000000000000000000000000001725 178.0
HFD2_k127_54408_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000006104 146.0
HFD2_k127_54408_3 Iron permease FTR1 K07243 - - 0.000000000000000000000000001192 123.0
HFD2_k127_54408_4 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.000000000000001691 80.0
HFD2_k127_5442950_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 531.0
HFD2_k127_5442950_1 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000005205 186.0
HFD2_k127_5442950_2 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000002051 156.0
HFD2_k127_5442950_4 PFAM Pentapeptide repeats (8 copies) - - - 0.0000000005274 63.0
HFD2_k127_5456301_0 serine-type peptidase activity - - - 4.064e-275 869.0
HFD2_k127_5456301_1 Proton-conducting membrane transporter K00342 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 4.215e-197 628.0
HFD2_k127_5456301_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 428.0
HFD2_k127_5456301_3 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005155 264.0
HFD2_k127_5456301_4 - - - - 0.00000000000000000000000000000000000000000000003218 175.0
HFD2_k127_5456301_5 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L - - - 0.0000000000000000000000000001473 119.0
HFD2_k127_5456301_6 Transposase - - - 0.0000000001313 72.0
HFD2_k127_5456301_7 PrcB C-terminal - - - 0.000001143 58.0
HFD2_k127_5457587_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1215.0
HFD2_k127_5457587_1 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000003386 84.0
HFD2_k127_5458627_0 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 406.0
HFD2_k127_5458627_1 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 311.0
HFD2_k127_5458627_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005247 287.0
HFD2_k127_5458627_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000001524 205.0
HFD2_k127_5458627_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000001724 103.0
HFD2_k127_5458627_5 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000058 96.0
HFD2_k127_5462763_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 351.0
HFD2_k127_5462763_1 Acyl-protein synthetase, LuxE K06046 - 6.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000004184 261.0
HFD2_k127_5462763_2 ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000002627 237.0
HFD2_k127_5462763_3 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.00000000000000000000000000008382 118.0
HFD2_k127_5462763_4 Acyl-CoA reductase (LuxC) - - - 0.000000000000000000000000004626 124.0
HFD2_k127_5466018_0 phage Terminase large subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 366.0
HFD2_k127_5466018_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003367 284.0
HFD2_k127_5466700_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 4.795e-228 713.0
HFD2_k127_5466700_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 6.737e-201 638.0
HFD2_k127_5466700_10 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000001441 102.0
HFD2_k127_5466700_11 protein secretion - - - 0.00000000000000001302 99.0
HFD2_k127_5466700_2 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 537.0
HFD2_k127_5466700_3 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 417.0
HFD2_k127_5466700_4 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000004098 219.0
HFD2_k127_5466700_5 cytochrome c nitrite reductase K15876 - - 0.000000000000000000000000000000000000000000000000000000002087 203.0
HFD2_k127_5466700_6 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000000000000000000000004163 179.0
HFD2_k127_5466700_7 Cation transport regulator - - - 0.000000000000000000000000000000000000000000000116 179.0
HFD2_k127_5466700_8 Zinc metalloprotease (Elastase) - - - 0.000000000000000000000000000000000001275 162.0
HFD2_k127_5466700_9 PFAM TrkA-C domain protein K11105 - - 0.00000000000000000000000000118 120.0
HFD2_k127_5482397_0 Polysaccharide biosynthesis C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002369 293.0
HFD2_k127_5482397_1 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000001389 147.0
HFD2_k127_5482397_2 acyl-CoA dehydrogenase K09479 GO:0000038,GO:0000062,GO:0000166,GO:0001659,GO:0003674,GO:0003824,GO:0003995,GO:0004466,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0005829,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0006986,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010033,GO:0010565,GO:0015980,GO:0016020,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0017099,GO:0019216,GO:0019217,GO:0019218,GO:0019222,GO:0019395,GO:0019752,GO:0019866,GO:0023052,GO:0030154,GO:0030258,GO:0030554,GO:0030855,GO:0030968,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033554,GO:0034440,GO:0034620,GO:0034976,GO:0035966,GO:0035967,GO:0036094,GO:0036498,GO:0042221,GO:0042304,GO:0042592,GO:0042645,GO:0042760,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046320,GO:0046322,GO:0046395,GO:0046890,GO:0048037,GO:0048519,GO:0048523,GO:0048856,GO:0048869,GO:0048871,GO:0050660,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051055,GO:0051716,GO:0055114,GO:0060429,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0070013,GO:0070887,GO:0071310,GO:0071704,GO:0072329,GO:0080090,GO:0090181,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.9 0.000006736 51.0
HFD2_k127_5510853_0 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 566.0
HFD2_k127_5510853_1 alanine dehydrogenase activity K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 321.0
HFD2_k127_5510853_2 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.00000000000000008124 85.0
HFD2_k127_5511203_0 CHAT domain - GO:0000922,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005813,GO:0005815,GO:0005819,GO:0005856,GO:0007346,GO:0008150,GO:0015630,GO:0019899,GO:0019900,GO:0030496,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044430,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051233,GO:0051726,GO:0065007,GO:0072686,GO:0097431,GO:1990023 - 0.000004111 59.0
HFD2_k127_5521336_0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000005165 207.0
HFD2_k127_5534124_0 PFAM peptidase M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005802 380.0
HFD2_k127_5534124_1 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.00000000000000000000000000000000000004669 152.0
HFD2_k127_5534124_2 - - - - 0.00004166 50.0
HFD2_k127_5546791_0 HAD superfamily (subfamily IG) hydrolase 5'-Nucleotidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 404.0
HFD2_k127_5546791_1 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000002577 253.0
HFD2_k127_5546791_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000008953 68.0
HFD2_k127_5567318_0 3-isopropylmalate dehydratase activity K01681,K01703,K01704,K17749 - 4.2.1.3,4.2.1.33,4.2.1.35 1.697e-221 702.0
HFD2_k127_5567318_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000002868 203.0
HFD2_k127_5567318_2 endonuclease activity K07451 - - 0.00000000000000000000000000000000000000004754 170.0
HFD2_k127_5567318_3 Ester cyclase - - - 0.00000000000000000000000000000000000000009625 153.0
HFD2_k127_5567318_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000001617 153.0
HFD2_k127_5567318_6 - - - - 0.000000000000000001094 94.0
HFD2_k127_5590312_0 Protein tyrosine kinase K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007764 330.0
HFD2_k127_5590312_1 Calcium/calmodulin dependent protein kinase II association domain - - - 0.0000000000000000000000000000000000000000000000001553 182.0
HFD2_k127_5630404_0 CHAT domain - - - 0.00000000000000000000000000001646 126.0
HFD2_k127_5630404_1 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000001811 87.0
HFD2_k127_5639142_0 TLC ATP/ADP transporter K03301 - - 0.00000000000003361 81.0
HFD2_k127_5639142_1 membrane organization - - - 0.00000000001723 77.0
HFD2_k127_566819_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 298.0
HFD2_k127_566819_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001296 253.0
HFD2_k127_566819_2 GDP-mannose 4,6 dehydratase K01784,K08678,K12454,K17947 - 4.1.1.35,5.1.3.10,5.1.3.2,5.1.3.25 0.00000000000000000002389 92.0
HFD2_k127_5668318_0 Permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009268 514.0
HFD2_k127_5668318_1 Cytochrome C biogenesis protein - - - 0.000000000000000000000000000000000000000000000000002359 196.0
HFD2_k127_5668318_2 - - - - 0.000000000000000000000000000006414 125.0
HFD2_k127_5668318_3 SMART regulatory protein ArsR - - - 0.000000000000000000001174 100.0
HFD2_k127_5668318_4 redox-active disulfide protein 2 - - - 0.000000000000000006253 93.0
HFD2_k127_5669653_0 PFAM Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 297.0
HFD2_k127_5669653_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000003533 183.0
HFD2_k127_5669653_2 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000000001608 157.0
HFD2_k127_5669653_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000007665 151.0
HFD2_k127_5669653_4 Transcriptional regulator - - - 0.00000000000000000000000002324 115.0
HFD2_k127_5669653_5 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000001029 114.0
HFD2_k127_5676318_0 Belongs to the peptidase S8 family K13276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000357 269.0
HFD2_k127_5676318_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000003852 169.0
HFD2_k127_5676318_2 Subtilase family - - - 0.00005539 55.0
HFD2_k127_5677385_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.868e-262 833.0
HFD2_k127_5677385_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 577.0
HFD2_k127_5677385_2 - - - - 0.000000000000000000000000000354 119.0
HFD2_k127_5677385_3 Hsp20/alpha crystallin family - - - 0.000000000000000002628 90.0
HFD2_k127_5677385_4 PFAM glycosyl transferase family 9 K02843 - - 0.000000000832 68.0
HFD2_k127_5677385_5 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000003018 56.0
HFD2_k127_5682697_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 351.0
HFD2_k127_5682697_1 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000005184 237.0
HFD2_k127_5682697_2 guanylate kinase activity K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000001952 192.0
HFD2_k127_5682697_3 DNA primase - - - 0.0000003309 61.0
HFD2_k127_5684955_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 8.004e-255 803.0
HFD2_k127_5684955_1 PFAM peptidase M16 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 344.0
HFD2_k127_5684955_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000103 235.0
HFD2_k127_5684955_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000001825 179.0
HFD2_k127_5684955_4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000006974 167.0
HFD2_k127_5684955_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000004524 132.0
HFD2_k127_5688815_0 Protein of unknown function (DUF2723) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006884 324.0
HFD2_k127_5688815_1 PFAM Rhodanese domain protein K03892 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002547 246.0
HFD2_k127_5688815_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000001131 177.0
HFD2_k127_5690138_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000004906 171.0
HFD2_k127_5690138_1 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000001255 164.0
HFD2_k127_5690138_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000003391 140.0
HFD2_k127_5690138_3 PFAM regulatory protein TetR - - - 0.00000000000000000000000002861 116.0
HFD2_k127_5700368_0 Helix-hairpin-helix motif K02237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000393 296.0
HFD2_k127_5705443_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 337.0
HFD2_k127_5705443_1 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 329.0
HFD2_k127_5705443_2 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000003455 257.0
HFD2_k127_5705443_3 HD domain - - - 0.0000000000000000000000000000000000000000000000000003269 199.0
HFD2_k127_5714316_0 purine nucleobase transmembrane transporter activity K06901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 359.0
HFD2_k127_5714316_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 335.0
HFD2_k127_5714316_2 nuclear chromosome segregation - - - 0.000000000000000000000000000653 124.0
HFD2_k127_5714316_3 ubiquitin - - - 0.000000000000000000000002069 115.0
HFD2_k127_5714316_4 cellulose binding K00505 - 1.14.18.1 0.000000001506 71.0
HFD2_k127_5721286_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 357.0
HFD2_k127_5721286_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 347.0
HFD2_k127_5721286_2 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.000000000000000000000000000000000000000000002102 173.0
HFD2_k127_5721286_3 endonuclease activity K07451 - - 0.00000000000000000359 92.0
HFD2_k127_5726178_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001586 280.0
HFD2_k127_5726178_1 PFAM Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000009794 220.0
HFD2_k127_5726178_2 ResB-like family - - - 0.0000000000000000000003002 111.0
HFD2_k127_5726178_3 PFAM ResB family protein K07399 - - 0.000000000000004511 88.0
HFD2_k127_5734056_0 4Fe-4S binding domain - - - 1.208e-264 835.0
HFD2_k127_5734056_1 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000005073 250.0
HFD2_k127_5734056_2 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000005744 224.0
HFD2_k127_5734056_3 Belongs to the UPF0403 family - - - 0.000000000000000000000000000000000000000000000003328 178.0
HFD2_k127_5734056_4 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000001958 131.0
HFD2_k127_5734056_5 Phosphomethylpyrimidine kinase K00941 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008902,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.49,2.7.4.7 0.000000000000000007118 87.0
HFD2_k127_5734399_0 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 484.0
HFD2_k127_5734399_1 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 417.0
HFD2_k127_5734399_10 oxidase subunit K08738 - - 0.000000000005048 73.0
HFD2_k127_5734399_11 - - - - 0.00000000001063 78.0
HFD2_k127_5734399_2 Beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009399 402.0
HFD2_k127_5734399_3 Cytochrome c K00425 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 368.0
HFD2_k127_5734399_4 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 288.0
HFD2_k127_5734399_5 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 288.0
HFD2_k127_5734399_6 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000001684 231.0
HFD2_k127_5734399_7 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.00000000000005111 81.0
HFD2_k127_5735388_0 glycosyl transferase family K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 1.94e-263 836.0
HFD2_k127_5735388_1 Glycosyl hydrolases family 15 K01178 - 3.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 444.0
HFD2_k127_5735388_2 Polysaccharide lyase family 4, domain II - - - 0.000000000000000000000000000000000000000000000000000000000000000000886 239.0
HFD2_k127_5735388_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000005622 188.0
HFD2_k127_5735388_4 Cytochrome oxidase assembly protein K02259,K03110 - - 0.000000000002052 70.0
HFD2_k127_5753417_0 Tetratricopeptide repeat - - - 0.0000000000000001208 94.0
HFD2_k127_5753417_1 heat shock protein binding - - - 0.0000000000000005066 87.0
HFD2_k127_5767375_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002517 278.0
HFD2_k127_5767375_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.000000000000000000000000000000000002903 143.0
HFD2_k127_5771971_0 lipid kinase activity - - - 0.000000000000000000000000000000000000000004176 175.0
HFD2_k127_5771971_1 - - - - 0.000001084 61.0
HFD2_k127_5771971_2 - - - - 0.00006354 54.0
HFD2_k127_5771971_3 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0004651 51.0
HFD2_k127_5772431_0 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000002773 104.0
HFD2_k127_5772431_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0000002553 63.0
HFD2_k127_57919_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006051 373.0
HFD2_k127_57919_1 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 347.0
HFD2_k127_57919_2 Ferrochelatase K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000001491 253.0
HFD2_k127_57919_3 RelA SpoT domain protein - - - 0.0000000000000000000000000000000000000000000000000000201 202.0
HFD2_k127_57919_4 Could be involved in septation K06412 - - 0.0000000000000001856 83.0
HFD2_k127_5798380_0 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003162 266.0
HFD2_k127_5798380_1 Transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002823 248.0
HFD2_k127_5798380_3 - - - - 0.00000000003265 66.0
HFD2_k127_5804489_0 Thiolase, C-terminal domain K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 448.0
HFD2_k127_5804489_1 Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities K01782 GO:0003674,GO:0003824,GO:0003857,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.35,4.2.1.17,5.1.2.3 0.0000000000000000000000000000000000000000000003734 173.0
HFD2_k127_5805576_0 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000008536 225.0
HFD2_k127_5805576_1 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000003877 85.0
HFD2_k127_5806677_0 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 331.0
HFD2_k127_5806677_1 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 325.0
HFD2_k127_5806677_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 301.0
HFD2_k127_5806677_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005124 258.0
HFD2_k127_5806677_4 RNA polymerase, sigma-24 subunit, ECF subfamily - - - 0.00000000000000000000002062 108.0
HFD2_k127_5822902_0 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 575.0
HFD2_k127_5822902_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 404.0
HFD2_k127_5822902_2 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 368.0
HFD2_k127_5822902_3 Hemerythrin HHE cation binding domain - - - 0.00000000000000000004118 99.0
HFD2_k127_5822902_5 - - - - 0.0000000000001634 80.0
HFD2_k127_5822902_7 Belongs to the UPF0312 family - - - 0.000002754 57.0
HFD2_k127_582787_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 2.387e-197 632.0
HFD2_k127_582787_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 454.0
HFD2_k127_582787_2 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.000000000003088 69.0
HFD2_k127_5829581_0 guanyl-nucleotide exchange factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 419.0
HFD2_k127_5829581_1 bacterial-type flagellum-dependent cell motility K01119,K06113,K12685,K20276 - 3.1.3.6,3.1.4.16,3.2.1.99 0.000000000592 72.0
HFD2_k127_5829581_2 Protein of unknown function (DUF3078) - - - 0.000001836 59.0
HFD2_k127_5840180_0 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 385.0
HFD2_k127_5840180_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 304.0
HFD2_k127_5840180_2 - - - - 0.000000000000000000000000001062 130.0
HFD2_k127_5840180_3 Subtilase family - - - 0.0000000000002848 78.0
HFD2_k127_5841409_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 597.0
HFD2_k127_5841409_1 Periplasmic component of the Tol biopolymer transport system K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 379.0
HFD2_k127_5841409_2 - - - - 0.0000000000000000003048 88.0
HFD2_k127_5870923_0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 290.0
HFD2_k127_5870923_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002072 254.0
HFD2_k127_5870923_2 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000001677 231.0
HFD2_k127_5870923_3 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000001992 178.0
HFD2_k127_5870923_4 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000001825 136.0
HFD2_k127_5870923_5 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000003489 118.0
HFD2_k127_5870923_6 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000002314 120.0
HFD2_k127_5870923_7 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000004648 108.0
HFD2_k127_5870923_8 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000007202 98.0
HFD2_k127_5870923_9 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000001835 64.0
HFD2_k127_5878799_0 COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 522.0
HFD2_k127_5878799_1 NHL repeat - - - 0.00000000000000000000000000000003658 138.0
HFD2_k127_5878857_0 ABC transporter, transmembrane K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 578.0
HFD2_k127_5878857_1 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000008461 237.0
HFD2_k127_5878857_2 ABC transporter, transmembrane K18890 - - 0.000000000000000000000000000000000000000002506 162.0
HFD2_k127_5878857_3 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000001262 154.0
HFD2_k127_5878857_4 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000007874 152.0
HFD2_k127_5878857_5 Receptor family ligand binding region - - - 0.000000000000000000000000598 108.0
HFD2_k127_5881712_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 556.0
HFD2_k127_5881712_1 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 291.0
HFD2_k127_5881712_2 Helix-hairpin-helix motif K14162 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000001109 228.0
HFD2_k127_5881712_3 FlgD Ig-like domain - - - 0.00000000000000000007823 91.0
HFD2_k127_5884154_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000005107 220.0
HFD2_k127_5911529_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 6.58e-261 818.0
HFD2_k127_5911529_1 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 422.0
HFD2_k127_5911529_2 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.000006093 48.0
HFD2_k127_5923637_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 494.0
HFD2_k127_5923637_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 459.0
HFD2_k127_5923637_2 OmpA family - - - 0.000000000000000000000000000000000000000000000000000008449 204.0
HFD2_k127_5923637_3 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000008746 130.0
HFD2_k127_5923637_4 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000566 79.0
HFD2_k127_5923637_5 TIGRFAM TonB family protein K03832 - - 0.000003187 59.0
HFD2_k127_5927242_0 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000005883 252.0
HFD2_k127_5927242_1 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000007199 129.0
HFD2_k127_5935095_0 pfkB family carbohydrate kinase K00847,K00852 - 2.7.1.15,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000546 268.0
HFD2_k127_5935095_1 isomerase activity K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000005113 263.0
HFD2_k127_5935095_2 Protein of unknown function (DUF3891) - - - 0.000000000000000000000000000000000000000000000000000000000000365 219.0
HFD2_k127_5935095_3 PFAM Rhomboid family protein K19225 - 3.4.21.105 0.000000000000000000000000000000000000002101 157.0
HFD2_k127_5935095_4 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.0000000000000000000000000000000629 130.0
HFD2_k127_5935095_5 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000004326 109.0
HFD2_k127_5935095_6 peptidyl-tyrosine sulfation - - - 0.00000000000000002131 96.0
HFD2_k127_5935095_7 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000009331 63.0
HFD2_k127_5944570_0 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 367.0
HFD2_k127_595976_0 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 348.0
HFD2_k127_595976_1 Protein of unknown function (DUF2723) - - - 0.000000000000000000000000000000000002612 159.0
HFD2_k127_595976_2 Peptidase M3A and M3B thimet oligopeptidase F - - - 0.0000001608 57.0
HFD2_k127_5966284_0 NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 351.0
HFD2_k127_5966284_1 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000003594 176.0
HFD2_k127_5966284_2 PFAM lipopolysaccharide biosynthesis - - - 0.00000000000000000000000000000000000001524 159.0
HFD2_k127_5966284_3 O-Antigen ligase - - - 0.0000000000000000000000000000000000903 150.0
HFD2_k127_5966284_4 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000004996 151.0
HFD2_k127_5966284_5 Polysaccharide deacetylase - - - 0.00000000000000000000000000001374 128.0
HFD2_k127_5966284_6 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000001122 127.0
HFD2_k127_5966284_7 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000003571 98.0
HFD2_k127_5968710_0 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 409.0
HFD2_k127_5968710_1 YbbR-like protein - - - 0.000000000000000000000000000003975 132.0
HFD2_k127_5968710_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530,K05788 - - 0.000000000000000000000000001979 114.0
HFD2_k127_5968710_3 GAF domain - - - 0.0000000000000000001025 91.0
HFD2_k127_5976936_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.769e-307 951.0
HFD2_k127_5976936_1 palmitoyl-(protein) hydrolase activity K01091 - 3.1.3.18 0.0000000000000000004308 96.0
HFD2_k127_5979741_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 4.893e-270 850.0
HFD2_k127_5979741_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 440.0
HFD2_k127_5979741_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 310.0
HFD2_k127_5979741_3 Could be involved in insertion of integral membrane proteins into the membrane K03217,K08998 - - 0.0000000000000000000000127 109.0
HFD2_k127_5979741_4 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000001851 88.0
HFD2_k127_5979741_5 Ribosomal protein L34 K02914 - - 0.00000000000007345 72.0
HFD2_k127_5979741_6 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.000000003728 63.0
HFD2_k127_5979741_7 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000001649 61.0
HFD2_k127_5979741_8 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000001142 56.0
HFD2_k127_5981430_0 Peptidase family M1 domain K01992 - - 0.0 1193.0
HFD2_k127_5981430_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 406.0
HFD2_k127_5981430_2 (ABC) transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 413.0
HFD2_k127_5981430_3 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 334.0
HFD2_k127_5981430_4 PFAM major facilitator superfamily MFS_1 K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001499 259.0
HFD2_k127_5981430_5 Belongs to the TrpC family K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000003477 222.0
HFD2_k127_5981430_6 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000002101 88.0
HFD2_k127_5981430_7 Cysteine-rich CPXCG - - - 0.000000000000000615 80.0
HFD2_k127_6022836_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008344 458.0
HFD2_k127_6022836_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000000000007998 155.0
HFD2_k127_6022836_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0001603 46.0
HFD2_k127_6039359_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 389.0
HFD2_k127_6039359_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000007143 231.0
HFD2_k127_6039359_2 Tricorn protease homolog - - - 0.0001727 45.0
HFD2_k127_6047910_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000005629 260.0
HFD2_k127_6047910_1 Surface antigen K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.00000000000000000000000000000000000000000000000000000000000006809 233.0
HFD2_k127_6047910_2 unfolded protein binding K06142 - - 0.0000000000000003665 85.0
HFD2_k127_6048831_0 ABC transporter - - - 1.008e-264 824.0
HFD2_k127_6048831_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 417.0
HFD2_k127_6048831_10 HD domain K07814 - - 0.000003917 58.0
HFD2_k127_6048831_2 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 354.0
HFD2_k127_6048831_3 Belongs to the arginase family K01476 GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 3.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 334.0
HFD2_k127_6048831_4 PFAM Fatty acid desaturase K04712 - 1.14.18.5,1.14.19.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 332.0
HFD2_k127_6048831_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 319.0
HFD2_k127_6048831_6 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007194 277.0
HFD2_k127_6048831_7 - - - - 0.00000000000000000000000000000004593 131.0
HFD2_k127_6048831_8 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.00000000000000000000000001214 114.0
HFD2_k127_6048831_9 Thioredoxin-like domain K03671 - - 0.00000000000000000000000003875 109.0
HFD2_k127_6049458_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006965 323.0
HFD2_k127_6049458_1 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.00000000000000000000000000000000000000000002019 177.0
HFD2_k127_6049458_2 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000002976 168.0
HFD2_k127_6049458_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.0000000003034 68.0
HFD2_k127_6051947_0 Cell wall-associated hydrolase (invasion-associated protein) - - - 0.000000000000000000000000000000000000008283 164.0
HFD2_k127_6051947_1 Peptidase M56 - - - 0.00000000000000000000000000000000001881 150.0
HFD2_k127_6051947_2 (Rhomboid) family - - - 0.0000000000000000001946 101.0
HFD2_k127_6051947_3 - - - - 0.0000002864 63.0
HFD2_k127_6055197_0 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 465.0
HFD2_k127_6055197_1 PFAM 4Fe-4S K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002418 269.0
HFD2_k127_6064671_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 390.0
HFD2_k127_6064671_1 HlyD family secretion protein K01993 - - 0.0000000000000000000000000000000000000000000000000000004213 206.0
HFD2_k127_6064671_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000003974 105.0
HFD2_k127_6064671_3 SMART Tetratricopeptide - - - 0.000000000000000000007447 105.0
HFD2_k127_6067458_0 - - - - 0.00000000000002021 87.0
HFD2_k127_608306_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 610.0
HFD2_k127_608306_1 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 504.0
HFD2_k127_608306_2 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007113 419.0
HFD2_k127_6084939_0 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000226 244.0
HFD2_k127_6084939_1 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000001272 128.0
HFD2_k127_6084939_2 DNA polymerase III subunits gamma and tau domain III K02343 GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 0.0000009294 58.0
HFD2_k127_6084939_3 PFAM phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0002511 49.0
HFD2_k127_6089158_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000004642 229.0
HFD2_k127_6089158_1 Belongs to the sigma-70 factor family K02405 - - 0.000000000000000000000000000000000000000000000000000000007732 207.0
HFD2_k127_6089158_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000009336 190.0
HFD2_k127_6089158_3 cell wall anchor domain - - - 0.00000000000002103 87.0
HFD2_k127_6089158_4 - - - - 0.0000000002009 74.0
HFD2_k127_6089158_5 Protein of unknown function (DUF1189) - - - 0.000009981 56.0
HFD2_k127_6103704_0 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000000000000003591 223.0
HFD2_k127_6103704_1 mannose-ethanolamine phosphotransferase activity - - - 0.00000000000000000000000000000000000000000000000000007238 199.0
HFD2_k127_6103704_2 PFAM Polysaccharide biosynthesis protein - - - 0.00000000003165 76.0
HFD2_k127_6103994_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 334.0
HFD2_k127_6103994_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007656 282.0
HFD2_k127_6103994_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000001339 198.0
HFD2_k127_6103994_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.00000000000000000000000000000000000000000000000000003412 200.0
HFD2_k127_6109022_0 Thymidine kinase K00857 - 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000003375 237.0
HFD2_k127_6109022_1 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000007464 93.0
HFD2_k127_6109022_2 cellulase activity K06882 - - 0.0000000000000008575 88.0
HFD2_k127_6109022_3 Transcriptional regulator - - - 0.000000006388 61.0
HFD2_k127_6109022_4 - - - - 0.0004775 50.0
HFD2_k127_6116816_0 CobW/HypB/UreG, nucleotide-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 586.0
HFD2_k127_6116816_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 415.0
HFD2_k127_6116816_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 404.0
HFD2_k127_6116816_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 328.0
HFD2_k127_6116816_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000004541 264.0
HFD2_k127_6116816_5 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000003303 194.0
HFD2_k127_6116816_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000002998 164.0
HFD2_k127_6116816_7 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000008785 112.0
HFD2_k127_6116816_8 Ribosomal L32p protein family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000000005438 91.0
HFD2_k127_6116816_9 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.00000257 50.0
HFD2_k127_611911_0 Transglycosylase - - - 8.35e-322 1017.0
HFD2_k127_611911_1 Glutamine synthetase, catalytic region K01915 - 6.3.1.2 7.777e-240 763.0
HFD2_k127_611911_2 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 467.0
HFD2_k127_611911_3 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000003506 200.0
HFD2_k127_6119268_0 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 368.0
HFD2_k127_6119268_1 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 348.0
HFD2_k127_6135834_0 Bacterial regulatory protein, Fis family K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001369 289.0
HFD2_k127_6135834_1 Evidence 5 No homology to any previously reported sequences K09607 - - 0.000000000000000000000000000000000000000000000000000000004141 217.0
HFD2_k127_6135834_2 cellulase activity K06882 - - 0.0000000000000000000000000000000000000000000000000000001746 206.0
HFD2_k127_6135834_3 PFAM AAA ATPase central domain protein - - - 0.000000000000000000000000000000000000000000000007661 190.0
HFD2_k127_6135834_4 cell adhesion involved in biofilm formation - - - 0.000000000000000000001487 103.0
HFD2_k127_6139569_0 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 9.567e-210 658.0
HFD2_k127_6139569_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 577.0
HFD2_k127_6139569_2 HMGL-like K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 338.0
HFD2_k127_6139569_3 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003334 278.0
HFD2_k127_6139569_4 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000007941 210.0
HFD2_k127_6139569_5 PFAM TonB-dependent receptor plug - - - 0.0001891 53.0
HFD2_k127_6150462_0 Protein of unknown function (DUF2867) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 558.0
HFD2_k127_6150462_1 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 393.0
HFD2_k127_6150462_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 345.0
HFD2_k127_6150462_3 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 332.0
HFD2_k127_6150462_4 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 309.0
HFD2_k127_6150462_5 Asparaginase K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 300.0
HFD2_k127_6150462_6 ABC transporter K01995,K01996,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 307.0
HFD2_k127_6150462_7 Zincin-like metallopeptidase - - - 0.00000000000000000000000000001801 123.0
HFD2_k127_6158743_0 - - - - 4.767e-306 971.0
HFD2_k127_6158743_1 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006075 350.0
HFD2_k127_6158743_2 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000007344 199.0
HFD2_k127_6158743_3 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.00000000000000000000000000000003698 128.0
HFD2_k127_6166993_0 Transport of potassium into the cell K03549 - - 4.476e-250 794.0
HFD2_k127_6166993_1 Transmembrane secretion effector K08225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 354.0
HFD2_k127_6166993_2 serine-type peptidase activity K01303 - 3.4.19.1 0.0000000000000000000000000000000000000000000000000000000000000001424 231.0
HFD2_k127_6166993_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000005808 175.0
HFD2_k127_6173012_0 Phenazine biosynthesis-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 325.0
HFD2_k127_6173012_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000002528 176.0
HFD2_k127_6173012_2 AsmA-like C-terminal region K07289,K09800 - - 0.00000000000274 78.0
HFD2_k127_6173012_3 - - - - 0.0000001454 56.0
HFD2_k127_6191025_0 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000006379 170.0
HFD2_k127_6191025_1 self proteolysis K01179,K01218 - 3.2.1.4,3.2.1.78 0.00004615 56.0
HFD2_k127_6214616_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 3.44e-238 762.0
HFD2_k127_6214616_1 Responsible for synthesis of pseudouridine from uracil K06177,K06180 GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000000000000000000000007102 254.0
HFD2_k127_6214616_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000001675 235.0
HFD2_k127_6214616_3 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000000000000000000000000007138 143.0
HFD2_k127_6214616_4 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000005259 111.0
HFD2_k127_6214616_5 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000219 110.0
HFD2_k127_6214616_6 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000000003225 102.0
HFD2_k127_6214616_7 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000000002017 104.0
HFD2_k127_6229313_0 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003605 282.0
HFD2_k127_6233302_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 385.0
HFD2_k127_6233302_1 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001585 289.0
HFD2_k127_6233302_2 MraW methylase family K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000002264 216.0
HFD2_k127_6233302_3 TIGRFAM stage V sporulation protein D K03587,K08384 - 3.4.16.4 0.00000000000000000000000000000001102 136.0
HFD2_k127_6233302_4 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000002271 109.0
HFD2_k127_624479_0 Belongs to the peptidase S8 family - - - 0.0000009048 63.0
HFD2_k127_624479_1 Lamin Tail Domain - - - 0.00006023 57.0
HFD2_k127_626478_0 Peptidase, M16 K07263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 5.196e-228 743.0
HFD2_k127_626478_1 AAA domain K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000001333 221.0
HFD2_k127_626478_2 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000000002504 111.0
HFD2_k127_626478_3 Uncharacterized protein conserved in bacteria (DUF2171) - - - 0.0000001249 61.0
HFD2_k127_6265056_0 Fructose-bisphosphate aldolase class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 517.0
HFD2_k127_6265056_1 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000006728 241.0
HFD2_k127_6265056_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000001121 136.0
HFD2_k127_6265056_3 biopolymer transport protein - - - 0.0000000000000000000000000001978 120.0
HFD2_k127_6265056_4 PFAM Biopolymer transport protein ExbD TolR - - - 0.0000000000000000000000143 104.0
HFD2_k127_6265056_5 of nitrite reductase and ring-hydroxylating dioxygenase K00363,K05710 - 1.7.1.15 0.0000000000000000005491 91.0
HFD2_k127_6265056_6 Belongs to the anti-sigma-factor antagonist family K04749 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000004664 71.0
HFD2_k127_6265056_7 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000002611 73.0
HFD2_k127_6265056_8 Tetratricopeptide repeat - - - 0.00003276 54.0
HFD2_k127_6273004_0 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000003019 149.0
HFD2_k127_6273004_1 metal-dependent phosphohydrolase HD region - - - 0.000000000001266 79.0
HFD2_k127_6283914_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000466 183.0
HFD2_k127_6283914_1 protein conserved in bacteria K09927 - - 0.0000000000000000000000000000002907 140.0
HFD2_k127_6286743_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 526.0
HFD2_k127_6286743_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 353.0
HFD2_k127_6286743_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000007823 234.0
HFD2_k127_6286743_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000001116 183.0
HFD2_k127_6322909_0 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 1.317e-224 702.0
HFD2_k127_6322909_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000003011 147.0
HFD2_k127_6337873_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 1.192e-292 909.0
HFD2_k127_6345116_0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 3.516e-258 809.0
HFD2_k127_6345116_1 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 432.0
HFD2_k127_6345116_2 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000001524 162.0
HFD2_k127_6345116_3 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000002049 125.0
HFD2_k127_6345116_4 cyclic nucleotide binding K00384,K01999,K07001,K10914 - 1.8.1.9 0.000000000001946 74.0
HFD2_k127_6345116_5 NAD(P)H-binding - - - 0.00000000001199 77.0
HFD2_k127_6345116_6 Rhomboid family K19225 - 3.4.21.105 0.0000000004463 72.0
HFD2_k127_6345116_7 Zn-ribbon protein possibly nucleic acid-binding - - - 0.00002252 55.0
HFD2_k127_6346479_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1407.0
HFD2_k127_6346479_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.0000000000000000000000000000000000000003115 152.0
HFD2_k127_6346479_2 Parallel beta-helix repeats - - - 0.0001529 53.0
HFD2_k127_6357652_0 Lanthionine synthetase C-like protein K20484 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004471 272.0
HFD2_k127_6357652_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000001242 241.0
HFD2_k127_6357652_2 ABC transporter - - - 0.0000000000001232 73.0
HFD2_k127_6360064_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003682 269.0
HFD2_k127_6360064_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000009157 167.0
HFD2_k127_6373584_0 SMART serine threonine protein kinase - - - 0.000000000000000000003463 109.0
HFD2_k127_6391707_0 photosystem II stabilization K02237 - - 0.00000000000000000000000000000000006656 144.0
HFD2_k127_6391707_1 metallopeptidase activity - - - 0.00000000000001412 83.0
HFD2_k127_6404368_0 Predicted membrane protein (DUF2339) - - - 0.00000000000000000003645 106.0
HFD2_k127_641167_0 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005065 528.0
HFD2_k127_641167_1 ACT domain K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007637 322.0
HFD2_k127_641167_2 FlgD Ig-like domain K13669 - - 0.00000000000000000000000000000000000002816 169.0
HFD2_k127_641167_3 FAD dependent oxidoreductase K00301 - 1.5.3.1 0.000000000000001053 79.0
HFD2_k127_6422090_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 365.0
HFD2_k127_6422090_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001636 273.0
HFD2_k127_6422090_2 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000001407 188.0
HFD2_k127_6422090_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000005719 178.0
HFD2_k127_6422090_4 Glycosyl hydrolase-like 10 - - - 0.000000000000000000000000000000000000000001253 173.0
HFD2_k127_6422090_5 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000469 133.0
HFD2_k127_6422090_6 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.0000000000000000000000000018 111.0
HFD2_k127_6422090_7 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000009374 68.0
HFD2_k127_6424217_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 402.0
HFD2_k127_6424217_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000002408 115.0
HFD2_k127_6444965_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.544e-196 632.0
HFD2_k127_6444965_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.00000000000000000000000000000000000000000000003112 177.0
HFD2_k127_6444965_2 - - - - 0.00000007101 63.0
HFD2_k127_6446429_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 310.0
HFD2_k127_6446429_1 PFAM Major Facilitator Superfamily - - - 0.000000000000000000001664 103.0
HFD2_k127_6462462_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 550.0
HFD2_k127_6462462_1 Protein of unknown function (DUF3494) - - - 0.0000000000003113 79.0
HFD2_k127_6493305_0 PFAM aminotransferase class I and II K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 396.0
HFD2_k127_6493305_1 Non-ribosomal peptide synthetase modules and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 363.0
HFD2_k127_6498968_0 6-phosphogluconolactonase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001866 272.0
HFD2_k127_6498968_1 Methyltransferase domain - - - 0.0000000000000000000000000000000001399 143.0
HFD2_k127_6498968_2 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000001255 62.0
HFD2_k127_6501968_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000212 241.0
HFD2_k127_6501968_1 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000003966 128.0
HFD2_k127_6501968_2 - - - - 0.000000000000000000000000005661 127.0
HFD2_k127_6501968_3 DDE superfamily endonuclease - - - 0.00000000000000000000001309 101.0
HFD2_k127_6501968_5 - - - - 0.000000002012 70.0
HFD2_k127_6506465_0 Phosphotransferase enzyme family - - - 0.000000000000003465 87.0
HFD2_k127_6558148_0 Transglycosylase SLT domain K08307,K12204 - - 0.000000000000000000000000000000000000000000000000000000000000000007632 247.0
HFD2_k127_6558148_1 TPR repeat - - - 0.000000001678 70.0
HFD2_k127_6558148_2 cell adhesion involved in biofilm formation - - - 0.000004848 57.0
HFD2_k127_6566980_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 472.0
HFD2_k127_6566980_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 354.0
HFD2_k127_6566980_2 similarity to GB CAH39666.1 - - - 0.00000000000000000000000000000000000000000000000001042 194.0
HFD2_k127_6566980_3 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.00000000000000000008823 103.0
HFD2_k127_6566980_4 WD40 domain protein beta Propeller K03641 - - 0.0000000000000000007519 100.0
HFD2_k127_6574277_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.503e-257 811.0
HFD2_k127_6574277_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000001944 261.0
HFD2_k127_6574277_10 Adenylate cyclase K01768 - 4.6.1.1 0.00000000000000000000001813 106.0
HFD2_k127_6574277_11 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000002754 103.0
HFD2_k127_6574277_12 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075,K15780 - 2.4.2.8,6.3.4.19 0.000000000000000000114 98.0
HFD2_k127_6574277_13 PFAM Photosynthetic reaction centre cytochrome C subunit K13992 - - 0.00000002198 61.0
HFD2_k127_6574277_14 Winged helix-turn-helix domain (DUF2582) - - - 0.00001612 52.0
HFD2_k127_6574277_2 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000003692 264.0
HFD2_k127_6574277_3 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000002304 230.0
HFD2_k127_6574277_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000000000000000000000000000000000000000000000000002185 211.0
HFD2_k127_6574277_5 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000002445 211.0
HFD2_k127_6574277_6 Uncharacterised protein family UPF0066 - - - 0.000000000000000000000000000000000000000000000000007155 183.0
HFD2_k127_6574277_7 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000002103 139.0
HFD2_k127_6574277_8 - - - - 0.0000000000000000000000000000000000255 143.0
HFD2_k127_6574277_9 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000003143 151.0
HFD2_k127_6576117_0 PFAM Alpha amylase, catalytic K01176 - 3.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001744 280.0
HFD2_k127_6576117_1 Metalloenzyme superfamily - - - 0.00000000000000000000000000000000000000000000000000000000004084 220.0
HFD2_k127_6582133_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 578.0
HFD2_k127_6582133_1 Tetratricopeptide TPR_2 repeat protein K12600 - - 0.00000000000000000000000000000000000008522 154.0
HFD2_k127_6582133_2 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000007121 98.0
HFD2_k127_6582133_3 Domain of unknown function DUF11 - - - 0.0000001864 63.0
HFD2_k127_6582133_4 Protein of unknown function (DUF3426) - - - 0.000002897 55.0
HFD2_k127_6586822_0 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 405.0
HFD2_k127_6586822_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006211 263.0
HFD2_k127_6586822_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000001319 98.0
HFD2_k127_6622750_0 POT family K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 550.0
HFD2_k127_6639042_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 6.06e-308 968.0
HFD2_k127_6639042_1 Prolyl oligopeptidase K01322 - 3.4.21.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 533.0
HFD2_k127_6639042_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000121 142.0
HFD2_k127_6642413_0 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 447.0
HFD2_k127_6642413_1 glycogen (starch) synthase activity - - - 0.0000000000000000000000000000000000006086 155.0
HFD2_k127_6642413_2 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000000000006044 130.0
HFD2_k127_6642413_3 PFAM glycosyl transferase group 1 - - - 0.00000000000000002448 96.0
HFD2_k127_6642413_4 C4-type zinc ribbon domain K07164 - - 0.0000000001271 67.0
HFD2_k127_6642413_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000001539 73.0
HFD2_k127_6649996_0 benzoyl-CoA reductase K04113 - 1.3.7.8 1.569e-195 617.0
HFD2_k127_6649996_1 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 486.0
HFD2_k127_6649996_2 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 473.0
HFD2_k127_6649996_3 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 307.0
HFD2_k127_6649996_4 stage II sporulation K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000004123 239.0
HFD2_k127_6649996_5 Enoyl-(Acyl carrier protein) reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.0000000000000000000000000000000000000000000000000003424 196.0
HFD2_k127_6649996_6 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000003862 135.0
HFD2_k127_6649996_8 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000002104 50.0
HFD2_k127_6656823_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000002304 239.0
HFD2_k127_6656823_1 isoprenoid biosynthetic process K00805,K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.30,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000007876 213.0
HFD2_k127_6656823_2 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000102 128.0
HFD2_k127_6686149_0 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 563.0
HFD2_k127_6686149_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008879 417.0
HFD2_k127_6686149_2 Glycosyl transferases group 1 K13668 GO:0000009,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0033164,GO:0040007,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.346 0.00000000000000000000000000000000000001293 153.0
HFD2_k127_6698331_0 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000001766 230.0
HFD2_k127_6698331_1 long-chain fatty acid transport protein - - - 0.000000000000000000000000002432 124.0
HFD2_k127_6698331_2 Belongs to the peptidase S8 family - - - 0.00000004416 65.0
HFD2_k127_6698538_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000004331 260.0
HFD2_k127_6698538_1 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000003571 199.0
HFD2_k127_6698538_2 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000003841 106.0
HFD2_k127_6698538_3 Sporulation and spore germination - - - 0.000000000000000001759 93.0
HFD2_k127_6707806_0 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003829 254.0
HFD2_k127_6707806_1 Fibronectin type 3 domain K06882 - - 0.000000000000000000000000000000000000103 156.0
HFD2_k127_6707806_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000003439 52.0
HFD2_k127_6718875_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 407.0
HFD2_k127_6718875_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000002276 142.0
HFD2_k127_6718875_2 His Kinase A (phosphoacceptor) domain K07709 - 2.7.13.3 0.0000007588 51.0
HFD2_k127_6718875_3 regulator K02483,K07666 - - 0.00001705 54.0
HFD2_k127_6718875_4 transcriptional regulator AraC family - - - 0.00003055 53.0
HFD2_k127_6728309_0 metallophosphoesterase K07096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 321.0
HFD2_k127_6728309_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 311.0
HFD2_k127_6728309_2 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000001556 229.0
HFD2_k127_6734084_0 Peptidase family M3 K01392 - 3.4.24.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 612.0
HFD2_k127_6734084_1 B12 binding domain K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005981 568.0
HFD2_k127_6743171_0 DEAD DEAH box helicase K03724 - - 5.723e-279 869.0
HFD2_k127_6743171_1 Belongs to the serpin family K13963 GO:0003674,GO:0004857,GO:0004866,GO:0004867,GO:0005575,GO:0005576,GO:0005615,GO:0008150,GO:0009892,GO:0010466,GO:0010605,GO:0010951,GO:0019222,GO:0030162,GO:0030234,GO:0030414,GO:0031323,GO:0031324,GO:0032268,GO:0032269,GO:0043086,GO:0044092,GO:0044421,GO:0045861,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0080090,GO:0098772 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 344.0
HFD2_k127_6746165_0 DEAD/H associated K03724 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747 607.0
HFD2_k127_6746165_1 Sodium/hydrogen exchanger family - - - 0.0000000000005202 81.0
HFD2_k127_6746165_2 cellulose binding - - - 0.000000004872 65.0
HFD2_k127_6746987_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K14534 - 4.2.1.120,5.3.3.3 7.83e-237 739.0
HFD2_k127_6746987_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006639 348.0
HFD2_k127_6769537_0 Quinolinate phosphoribosyl transferase, N-terminal domain K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000134 273.0
HFD2_k127_6769537_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000005944 189.0
HFD2_k127_6769537_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000005636 155.0
HFD2_k127_6769537_3 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000005658 49.0
HFD2_k127_6789082_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008354 361.0
HFD2_k127_6789082_1 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000006699 156.0
HFD2_k127_6789082_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000002984 162.0
HFD2_k127_6789082_3 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000001865 136.0
HFD2_k127_6789082_4 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000001134 130.0
HFD2_k127_6789082_5 thiamine biosynthesis protein ThiS K03154 - - 0.0000000007843 67.0
HFD2_k127_6793691_0 glutamate dehydrogenase [NAD(P)+] activity K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 9.516e-222 696.0
HFD2_k127_6793691_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 1.722e-209 666.0
HFD2_k127_6793691_2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.00000000001205 67.0
HFD2_k127_6799421_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 1.431e-272 857.0
HFD2_k127_6825735_0 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000003329 222.0
HFD2_k127_6825735_1 PFAM oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000003107 202.0
HFD2_k127_6825735_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000009226 163.0
HFD2_k127_6831667_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006749 349.0
HFD2_k127_6831667_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000007698 182.0
HFD2_k127_6831667_2 Protein of unknown function, DUF547 - - - 0.00000000000000000002445 95.0
HFD2_k127_6846938_0 PFAM metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000000005257 173.0
HFD2_k127_6846938_1 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000002749 141.0
HFD2_k127_6846938_2 peptidyl-tyrosine sulfation - - - 0.0000000000000178 84.0
HFD2_k127_6853517_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 461.0
HFD2_k127_6853517_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 332.0
HFD2_k127_6853517_2 LVIVD repeat - - - 0.000000000000000000000000000000002405 149.0
HFD2_k127_6853517_3 Ribosomal protein S21 K02970 - - 0.0000000000000009582 79.0
HFD2_k127_6861986_0 4-hydroxybenzoate polyprenyltransferase K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000003707 216.0
HFD2_k127_6861986_1 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000001143 209.0
HFD2_k127_6861986_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000001919 152.0
HFD2_k127_6863183_0 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008155 278.0
HFD2_k127_6863183_1 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000008844 204.0
HFD2_k127_6863183_2 OsmC-like protein K04063 - - 0.000000000000000000000000000000000000000000000387 168.0
HFD2_k127_686990_0 SMART Nucleotide binding protein, PINc K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 486.0
HFD2_k127_686990_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000001813 178.0
HFD2_k127_6879119_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0 1045.0
HFD2_k127_6879119_1 Dienelactone hydrolase family - - - 7.737e-255 801.0
HFD2_k127_6879119_2 Bacterial protein of unknown function (DUF885) - - - 3.269e-201 646.0
HFD2_k127_6879119_3 endonuclease activity K07451 - - 0.000000000000000000002641 96.0
HFD2_k127_6879119_4 Ribbon-helix-helix protein, copG family - - - 0.000001277 58.0
HFD2_k127_6879119_5 Histidine kinase - - - 0.000001285 59.0
HFD2_k127_6879229_0 PFAM Ribonuclease BN-like family K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 344.0
HFD2_k127_6879229_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 298.0
HFD2_k127_6879229_2 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000000000000000000003926 201.0
HFD2_k127_6879229_3 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000002238 195.0
HFD2_k127_6890812_0 PFAM aldo keto reductase K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 466.0
HFD2_k127_6890812_1 Domain of unknown function (DUF4340) - - - 0.00000000721 66.0
HFD2_k127_6890812_2 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.0000001389 53.0
HFD2_k127_6898301_0 PFAM peptidase M16 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 332.0
HFD2_k127_6898301_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K05886 - 1.1.1.276 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009378 313.0
HFD2_k127_6898301_2 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000001404 206.0
HFD2_k127_6898301_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000001019 107.0
HFD2_k127_6900515_0 palmitoyl-(protein) hydrolase activity K01091 - 3.1.3.18 0.0000000000000000001041 96.0
HFD2_k127_6920859_0 C-terminal, D2-small domain, of ClpB protein K11907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007436 527.0
HFD2_k127_6930046_0 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.151e-194 621.0
HFD2_k127_6930046_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000002007 264.0
HFD2_k127_6930046_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000004431 78.0
HFD2_k127_6936981_0 protein conserved in bacteria K11891 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 326.0
HFD2_k127_6936981_1 Type VI secretion system protein DotU K11892 - - 0.000000000000000000018 102.0
HFD2_k127_6936981_2 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 0.00000000000000000008694 95.0
HFD2_k127_6937897_0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.0 1041.0
HFD2_k127_6937897_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain - - - 1.226e-207 659.0
HFD2_k127_6937897_2 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 1.139e-204 649.0
HFD2_k127_6937897_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009147 505.0
HFD2_k127_6937897_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 310.0
HFD2_k127_6937897_5 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000003643 198.0
HFD2_k127_6937897_6 Belongs to the complex I subunit 6 family K00339 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000000000000002543 162.0
HFD2_k127_6937897_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000001951 140.0
HFD2_k127_69418_0 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004128 282.0
HFD2_k127_69418_1 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000005676 257.0
HFD2_k127_6946656_0 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 417.0
HFD2_k127_6946656_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 330.0
HFD2_k127_6946656_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000009451 183.0
HFD2_k127_6946656_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000001356 179.0
HFD2_k127_6946656_4 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000004083 168.0
HFD2_k127_6946656_5 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000006974 136.0
HFD2_k127_6948389_0 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 332.0
HFD2_k127_6948389_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001185 278.0
HFD2_k127_6948389_2 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000005267 170.0
HFD2_k127_6948389_3 NHL repeat - - - 0.0000000000000000000001598 111.0
HFD2_k127_6948389_4 extracellular matrix structural constituent - - - 0.000000000000001916 90.0
HFD2_k127_6955264_0 Dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 414.0
HFD2_k127_6955264_1 acetyltransferase - - - 0.0000000000000000000000000000000000000002485 153.0
HFD2_k127_6955264_2 - - - - 0.00002958 56.0
HFD2_k127_696567_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 340.0
HFD2_k127_696567_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 302.0
HFD2_k127_696567_2 - - - - 0.0000002437 56.0
HFD2_k127_6969827_0 PFAM Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 297.0
HFD2_k127_6969827_1 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003256 271.0
HFD2_k127_6969827_2 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005515 270.0
HFD2_k127_6969827_3 Peptidase M15 - - - 0.00000000000000000000000000000001308 135.0
HFD2_k127_6969827_4 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.000000000000001371 77.0
HFD2_k127_6969827_5 YtxH-like protein - - - 0.000002722 53.0
HFD2_k127_6969827_6 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000303 57.0
HFD2_k127_69801_0 CBS domain-containing protein K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 392.0
HFD2_k127_69801_1 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005545 361.0
HFD2_k127_69801_2 SMART Elongator protein 3 MiaB NifB K22227 - - 0.000000000000000000000004839 115.0
HFD2_k127_69801_3 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.000000000000000004109 90.0
HFD2_k127_69801_4 NUDIX domain - - - 0.000007772 53.0
HFD2_k127_6998803_0 cellulase activity K01179 - 3.2.1.4 0.000000002104 70.0
HFD2_k127_6998803_1 - - - - 0.0004989 52.0
HFD2_k127_7006482_0 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K22110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 302.0
HFD2_k127_7006482_1 Zinc carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000003229 204.0
HFD2_k127_7029956_0 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 381.0
HFD2_k127_7029956_1 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000137 248.0
HFD2_k127_7062674_0 serine-type peptidase activity K01278,K06889 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005454 357.0
HFD2_k127_7073895_0 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 471.0
HFD2_k127_7073895_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000911 297.0
HFD2_k127_7073895_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000001026 158.0
HFD2_k127_7073895_3 SPFH domain-Band 7 family - - - 0.0000318 57.0
HFD2_k127_7073895_4 Alpha beta hydrolase - - - 0.0003189 45.0
HFD2_k127_7076877_0 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000002824 214.0
HFD2_k127_7076877_1 Helix-turn-helix diphteria tox regulatory element - - - 0.000000009497 59.0
HFD2_k127_7091680_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000000000004063 196.0
HFD2_k127_7091680_1 Protein of unknown function (DUF1501) - - - 0.000000000000003155 89.0
HFD2_k127_7095889_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000005636 173.0
HFD2_k127_7095889_1 PFAM phosphatidate cytidylyltransferase K18678 - 2.7.1.182 0.000000000000000000000000000000000000001109 157.0
HFD2_k127_7095889_2 epimerase dehydratase - - - 0.00000001389 62.0
HFD2_k127_7097782_0 Tricorn protease homolog K08676 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 503.0
HFD2_k127_7132336_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 512.0
HFD2_k127_7132336_1 DNA polymerase alpha chain like domain K02347 - - 0.00000000000000000000000000000000002467 138.0
HFD2_k127_7132336_2 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.0000000000000000000000000000000745 134.0
HFD2_k127_7139281_0 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000007664 150.0
HFD2_k127_7139281_1 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 - 2.4.1.109 0.000174 53.0
HFD2_k127_7140050_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007267 588.0
HFD2_k127_7140050_1 Methyltransferase domain - - - 0.00000000000000000000002779 111.0
HFD2_k127_7158423_0 - K03561,K12287 - - 0.00000000000000000000000000000000006782 153.0
HFD2_k127_7158423_1 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000001807 81.0
HFD2_k127_7160562_0 serine-type peptidase activity K01303 - 3.4.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 350.0
HFD2_k127_7160562_1 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 2.1.1.63 0.000000000000000000000002013 107.0
HFD2_k127_7160562_2 Thioredoxin-like - - - 0.0000000000002422 74.0
HFD2_k127_7162_0 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 457.0
HFD2_k127_7162_1 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 445.0
HFD2_k127_7162_2 methyltransferase - - - 0.000000000000000000000000000000000000000001008 175.0
HFD2_k127_7162_3 Evidence 5 No homology to any previously reported sequences K03088 - - 0.0000000000002247 80.0
HFD2_k127_7162912_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009606 553.0
HFD2_k127_7162912_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 442.0
HFD2_k127_7162912_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 432.0
HFD2_k127_7162912_3 PFAM Thiamine pyrophosphate K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007297 382.0
HFD2_k127_7162912_4 phosphatidate phosphatase activity K09474,K19302 - 3.1.3.2,3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000007965 256.0
HFD2_k127_7162912_5 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000006837 218.0
HFD2_k127_7162912_6 phosphatidate phosphatase activity K09474,K19302 - 3.1.3.2,3.6.1.27 0.0000000000000001061 89.0
HFD2_k127_7162912_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000008812 69.0
HFD2_k127_716571_0 Thermophilic metalloprotease (M29) K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 490.0
HFD2_k127_716571_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009793 302.0
HFD2_k127_716571_2 Evidence 5 No homology to any previously reported sequences K20952 - - 0.0000000000000003206 94.0
HFD2_k127_716571_3 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000002615 88.0
HFD2_k127_716571_4 - - - - 0.0003077 52.0
HFD2_k127_7183369_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000004646 113.0
HFD2_k127_7189478_0 PFAM multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 540.0
HFD2_k127_7190867_0 ATPase associated with various cellular K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 459.0
HFD2_k127_7190867_1 Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008757 362.0
HFD2_k127_7190867_2 von Willebrand factor (vWF) type A domain K07114,K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 315.0
HFD2_k127_7190867_3 Oxygen tolerance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 319.0
HFD2_k127_7190867_4 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001403 293.0
HFD2_k127_7190867_5 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000487 108.0
HFD2_k127_7190867_6 TPR repeat - - - 0.0000000000000000249 91.0
HFD2_k127_7203676_0 cellulose binding - - - 2.743e-218 680.0
HFD2_k127_7203676_1 NADH flavin oxidoreductase NADH oxidase K09461 - 1.14.13.40 0.00000000000000000000000000000000000000000000003072 184.0
HFD2_k127_7203676_2 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000002223 147.0
HFD2_k127_7203676_3 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.0000417 51.0
HFD2_k127_7228209_0 bacterial-type flagellum organization K02282,K04562 - - 0.00000000000000000000000000000000000000000000000000000001759 217.0
HFD2_k127_7228209_1 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000004706 169.0
HFD2_k127_7235015_0 Glycosyl transferases group 1 - - - 0.00000000000000000000002633 106.0
HFD2_k127_7235015_1 Phosphotransferase enzyme family - - - 0.0000000008059 72.0
HFD2_k127_7245518_0 acetyl-CoA hydrolase K18118 - 2.8.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 535.0
HFD2_k127_7245518_1 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008193 364.0
HFD2_k127_7245518_2 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 310.0
HFD2_k127_7245518_3 acetyl-CoA hydrolase K18118 - 2.8.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004604 270.0
HFD2_k127_7245518_4 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004935 259.0
HFD2_k127_7245518_5 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003803 245.0
HFD2_k127_7245518_6 endonuclease activity K07451 - - 0.00000000000000000000000000000000000000000000004608 185.0
HFD2_k127_7245845_0 Protein of unknown function (DUF2400) K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000004389 262.0
HFD2_k127_7245845_1 Isochorismatase family K08281 - 3.5.1.19 0.0000000000001042 83.0
HFD2_k127_7245845_2 Sugar-specific transcriptional regulator TrmB - - - 0.000000000006176 77.0
HFD2_k127_7245845_3 Major Facilitator Superfamily - - - 0.0000000005491 72.0
HFD2_k127_7245845_4 domain protein K20276 - - 0.000003953 59.0
HFD2_k127_7245845_5 Glycine zipper - - - 0.0001503 53.0
HFD2_k127_7254189_0 Polysaccharide biosynthesis protein K12454 - 5.1.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 382.0
HFD2_k127_7254189_1 endonuclease activity K07451 - - 0.00000000000000001702 98.0
HFD2_k127_7257351_0 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000003406 177.0
HFD2_k127_7257351_1 - - - - 0.00000591 59.0
HFD2_k127_7260204_0 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.0000000004429 73.0
HFD2_k127_7260204_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000008759 59.0
HFD2_k127_728545_0 Cytochrome b subunit of formate dehydrogenase-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 342.0
HFD2_k127_728545_1 formate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000686 207.0
HFD2_k127_728545_2 amine dehydrogenase activity K21449 - - 0.00000000000000000000000000000000004583 140.0
HFD2_k127_728545_3 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000004981 130.0
HFD2_k127_732267_0 Dehydrogenase E1 component K11381 - 1.2.4.4 7.399e-234 739.0
HFD2_k127_7323789_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 357.0
HFD2_k127_7323789_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001969 264.0
HFD2_k127_7323789_2 -O-antigen K18814 - - 0.0000000000000000000000000008051 130.0
HFD2_k127_7323789_3 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000001289 62.0
HFD2_k127_7326128_0 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 334.0
HFD2_k127_7326128_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000001703 215.0
HFD2_k127_7326128_2 metallopeptidase activity K06402 - - 0.00000000000000000000000000000000000000000000000000004816 194.0
HFD2_k127_7326128_3 Thioredoxin-like - - - 0.000000000000000000000000002268 114.0
HFD2_k127_7326128_4 Tryptophanyl-tRNA synthetase K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.000000000004215 73.0
HFD2_k127_7326128_5 Thioredoxin-like - - - 0.0000008843 53.0
HFD2_k127_7330055_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 398.0
HFD2_k127_7330055_1 amidohydrolase K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005546 361.0
HFD2_k127_7330055_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009873 314.0
HFD2_k127_7330055_3 Aldolase K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000002785 220.0
HFD2_k127_7330055_4 lyase activity - - - 0.0000000000000000000000000000000000000000000000001675 203.0
HFD2_k127_7330055_5 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.0000000000000000000000000000000000002468 150.0
HFD2_k127_7330055_6 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000003178 79.0
HFD2_k127_7341012_0 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 291.0
HFD2_k127_7341012_1 Sugar (and other) transporter - - - 0.000000000000000000000000003079 121.0
HFD2_k127_7341012_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000002488 109.0
HFD2_k127_7344472_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 400.0
HFD2_k127_7344472_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 375.0
HFD2_k127_7344472_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000001779 117.0
HFD2_k127_7344472_3 Belongs to the complex I subunit 6 family K00339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000005545 115.0
HFD2_k127_7356916_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000102 224.0
HFD2_k127_7356916_1 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.0000000000000000000000000000000000000001207 160.0
HFD2_k127_7356916_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000004969 131.0
HFD2_k127_7356916_3 Transcription elongation factor, N-terminal K03624 - - 0.00000000000000009423 93.0
HFD2_k127_7356916_4 OsmC-like protein K07397 - - 0.0000009796 59.0
HFD2_k127_7360413_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0 1013.0
HFD2_k127_7360413_1 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 1.986e-239 768.0
HFD2_k127_7360413_2 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002922 250.0
HFD2_k127_7360413_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000007091 238.0
HFD2_k127_7360413_4 Amino acid permease - - - 0.00000000000000000000000000000000000001194 147.0
HFD2_k127_7363172_0 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 404.0
HFD2_k127_7363172_1 - K02275,K17686 - 1.9.3.1,3.6.3.54 0.0000000000000000009024 91.0
HFD2_k127_7393305_0 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000001718 203.0
HFD2_k127_7393305_1 Metal-dependent hydrolases of the beta-lactamase superfamily III - - - 0.000000000000000000000000000000000000000000000002791 182.0
HFD2_k127_7393305_2 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000001504 129.0
HFD2_k127_7393305_5 COGs COG1629 Outer membrane receptor protein mostly Fe transport - - - 0.000005058 57.0
HFD2_k127_7402231_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 581.0
HFD2_k127_7402231_1 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000003616 55.0
HFD2_k127_7403697_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.395e-207 669.0
HFD2_k127_7403697_1 Participates in both transcription termination and antitermination K02600 GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 420.0
HFD2_k127_7403697_2 Peptidase M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006617 283.0
HFD2_k127_7403697_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000006624 122.0
HFD2_k127_7403697_4 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000004984 117.0
HFD2_k127_7403697_5 Protein of unknown function (DUF503) K09764 - - 0.000000000009346 68.0
HFD2_k127_7404685_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 305.0
HFD2_k127_7404685_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000001275 214.0
HFD2_k127_7404685_2 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000001938 213.0
HFD2_k127_7404685_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000002963 140.0
HFD2_k127_7404685_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000006377 121.0
HFD2_k127_7404685_5 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000003016 86.0
HFD2_k127_7404685_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000197 57.0
HFD2_k127_7404685_7 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000004949 53.0
HFD2_k127_7408824_0 Putative adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006808 250.0
HFD2_k127_7408824_1 Putative adhesin - - - 0.00000000000000000005593 102.0
HFD2_k127_7408824_2 Carbohydrate family 9 binding domain-like - - - 0.0001727 48.0
HFD2_k127_7430297_0 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 535.0
HFD2_k127_7430297_1 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009657 542.0
HFD2_k127_7430297_2 Belongs to the ClpA ClpB family K03695,K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 519.0
HFD2_k127_7430297_3 ABC-type transport system involved in lipoprotein release permease component K02004,K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 356.0
HFD2_k127_7430297_4 Catalyzes the specific phosphorylation of arginine residues in proteins K19405 - 2.7.14.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 332.0
HFD2_k127_7430297_5 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000172 243.0
HFD2_k127_7430297_6 Psort location Cytoplasmic, score 8.96 K19411 - - 0.00000000000000000000000000000007751 134.0
HFD2_k127_7430297_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000005303 125.0
HFD2_k127_7430297_8 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000007749 97.0
HFD2_k127_7443153_0 NAD binding K00333,K13378 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 503.0
HFD2_k127_7443153_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 461.0
HFD2_k127_7443153_10 Glycosyl hydrolase-like 10 - - - 0.00000000000000000000002212 114.0
HFD2_k127_7443153_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000008579 102.0
HFD2_k127_7443153_12 selT selW selH selenoprotein K07401 - - 0.00000000006934 64.0
HFD2_k127_7443153_13 Tetratricopeptide repeat - - - 0.0001488 53.0
HFD2_k127_7443153_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001648 275.0
HFD2_k127_7443153_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000002229 245.0
HFD2_k127_7443153_4 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.00000000000000000000000000000000000000000000000000000000006549 218.0
HFD2_k127_7443153_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03615,K05580 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000094 193.0
HFD2_k127_7443153_6 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.000000000000000000000000000000000000000000000001557 186.0
HFD2_k127_7443153_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000006024 166.0
HFD2_k127_7443153_8 fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000002449 137.0
HFD2_k127_7443153_9 chlorophyll binding - - - 0.0000000000000000000000000000000002511 148.0
HFD2_k127_7446173_0 - - - - 0.0000000000000000000000000000000000003256 147.0
HFD2_k127_7446173_1 Protein tyrosine kinase - - - 0.0000000000000000000000000000007587 125.0
HFD2_k127_7446173_2 - - - - 0.0000000000000000000000000003975 120.0
HFD2_k127_7446173_3 Transglycosylase associated protein - - - 0.00000000000000000000001626 101.0
HFD2_k127_7446173_4 Lysin motif - - - 0.000000000000000008308 87.0
HFD2_k127_7457028_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001349 260.0
HFD2_k127_7457028_1 - - - - 0.000005952 54.0
HFD2_k127_7459571_0 lysine biosynthetic process via aminoadipic acid - - - 5.916e-227 734.0
HFD2_k127_7459571_1 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 475.0
HFD2_k127_7459571_2 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000004634 244.0
HFD2_k127_7459571_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000006414 125.0
HFD2_k127_7473247_0 PFAM Peptidase M20 K01439 - 3.5.1.18 0.00000000000000000000000000000000009136 149.0
HFD2_k127_7480461_0 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000592 427.0
HFD2_k127_7480461_1 Group 1 family - - - 0.00000000000000000000000000000000000000000000000000518 204.0
HFD2_k127_7480461_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000005558 126.0
HFD2_k127_7480461_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000006854 108.0
HFD2_k127_7480461_4 periplasmic ligand-binding sensor domain - - - 0.000000000007092 71.0
HFD2_k127_7480461_5 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00001475 58.0
HFD2_k127_7480461_6 - - - - 0.0004457 52.0
HFD2_k127_7480461_7 Polysaccharide biosynthesis protein K03328,K16695 - - 0.0006003 52.0
HFD2_k127_7502954_0 purine nucleobase transmembrane transporter activity K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002483 258.0
HFD2_k127_7502954_1 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000002775 178.0
HFD2_k127_7502954_2 DoxX - - - 0.000000000000000000000000000000006137 132.0
HFD2_k127_7502954_3 SdrD B-like domain - - - 0.000000001174 69.0
HFD2_k127_7508380_0 transmembrane transporter activity - - - 2.2e-322 1019.0
HFD2_k127_7508380_1 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667,K01668 - 4.1.99.1,4.1.99.2 4.297e-244 764.0
HFD2_k127_7508380_2 peptidase, M20 K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 434.0
HFD2_k127_7508380_3 - - - - 0.00000000000000000000000000000000000000000000000000000000002192 213.0
HFD2_k127_7508380_4 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000002188 208.0
HFD2_k127_7508380_5 Putative zinc-finger K03088 - - 0.000000000000000000000000000000000000000000193 171.0
HFD2_k127_7508380_6 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000000000007927 141.0
HFD2_k127_7508380_7 HlyD family secretion protein - - - 0.0000000000000000000000001882 122.0
HFD2_k127_7508380_8 Protein of unknown function (DUF2892) - - - 0.00000000000000005954 94.0
HFD2_k127_7534591_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004083 462.0
HFD2_k127_7534591_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006546 309.0
HFD2_k127_7534591_2 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004688 263.0
HFD2_k127_7534591_3 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000003298 201.0
HFD2_k127_7535017_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 2.105e-226 707.0
HFD2_k127_7556444_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 458.0
HFD2_k127_7556444_1 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000002147 200.0
HFD2_k127_7556444_3 NYN domain - - - 0.000000000000000000278 96.0
HFD2_k127_7561275_0 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 493.0
HFD2_k127_7561275_1 PFAM DGPFAETKE family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000004081 233.0
HFD2_k127_7563150_0 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000000000000000002896 211.0
HFD2_k127_7563150_2 peptidyl-tyrosine sulfation - - - 0.00001091 57.0
HFD2_k127_7568294_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 344.0
HFD2_k127_7568294_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000008095 163.0
HFD2_k127_7568294_2 Low molecular weight phosphatase family K01104 - 3.1.3.48 0.000000000000000000000000000234 121.0
HFD2_k127_756909_0 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001034 280.0
HFD2_k127_756909_1 Beta-lactamase - - - 0.0000001026 58.0
HFD2_k127_756909_2 Cytochrome c - - - 0.000001456 57.0
HFD2_k127_757056_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 310.0
HFD2_k127_757056_1 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002729 271.0
HFD2_k127_757056_2 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000001431 203.0
HFD2_k127_757056_3 Surface antigen K07277 - - 0.0000000000000000000000000000000000000000531 173.0
HFD2_k127_7571028_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 427.0
HFD2_k127_7571028_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 389.0
HFD2_k127_7571028_2 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 326.0
HFD2_k127_757424_0 candidate b-glycosidase, glycoside hydrolase family 8 protein - - - 0.0000000000000000000000000000000000000000001431 183.0
HFD2_k127_7577026_0 Glycosyl transferase WecB/TagA/CpsF family K05946 - 2.4.1.187 0.000000000000000000000000000000000000000000000000000005543 211.0
HFD2_k127_7577026_1 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000001531 147.0
HFD2_k127_7577026_2 Polysaccharide biosynthesis protein - - - 0.0000000000000009373 89.0
HFD2_k127_7578468_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 383.0
HFD2_k127_7578468_1 FG-GAP repeat - - - 0.000000000000000000000000000000000000000000000000004862 208.0
HFD2_k127_7578468_2 FG-GAP repeat - - - 0.0000000000000000000009136 102.0
HFD2_k127_7578468_3 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000001573 95.0
HFD2_k127_7578468_4 Two component regulator propeller - - - 0.000000604 63.0
HFD2_k127_7624960_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 419.0
HFD2_k127_7624960_1 Alanine-glyoxylate amino-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 390.0
HFD2_k127_7632623_0 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 389.0
HFD2_k127_7668734_0 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 451.0
HFD2_k127_7668734_1 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 374.0
HFD2_k127_7682288_0 transport, permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 324.0
HFD2_k127_7682288_1 transport, permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 316.0
HFD2_k127_7682288_2 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000294 243.0
HFD2_k127_7682288_3 PFAM ABC transporter related K01990 - - 0.00000004086 57.0
HFD2_k127_768650_0 amine dehydrogenase activity - - - 1.26e-259 832.0
HFD2_k127_769516_0 Belongs to the peptidase M16 family K07263 - - 1.285e-312 985.0
HFD2_k127_769516_1 PFAM DNA primase small subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 613.0
HFD2_k127_769516_2 ATP dependent DNA ligase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 542.0
HFD2_k127_769516_3 PFAM Sodium sulphate symporter K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 488.0
HFD2_k127_769516_4 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 306.0
HFD2_k127_769516_5 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms K07027,K14205 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 0.0000000000000000000000000000000000000000000000000000000168 224.0
HFD2_k127_769516_6 His Kinase A (phospho-acceptor) domain - - - 0.00000000000000000000000000000000002236 156.0
HFD2_k127_769516_7 CHAT domain - - - 0.0000000000000000000000003394 111.0
HFD2_k127_769516_8 - - - - 0.00000000000000000000001185 112.0
HFD2_k127_7704650_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1245.0
HFD2_k127_7704650_1 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00207,K12527,K17723 - 1.3.1.1,1.3.1.2,1.97.1.9 1.082e-223 714.0
HFD2_k127_7704650_10 PKD domain K07282 - - 0.000000000000001052 92.0
HFD2_k127_7704650_11 Belongs to the glycosyl hydrolase 18 family - - - 0.000000001861 71.0
HFD2_k127_7704650_13 Tetratricopeptide repeat - - - 0.0005135 50.0
HFD2_k127_7704650_2 Belongs to the ATCase OTCase family - GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0019627,GO:0034641,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002581 284.0
HFD2_k127_7704650_3 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000005282 274.0
HFD2_k127_7704650_4 dihydrofolate reductase activity K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000001872 248.0
HFD2_k127_7704650_6 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000003062 188.0
HFD2_k127_7704650_7 glycine decarboxylation via glycine cleavage system K02437 - - 0.000000000000000000000000000000000000000000004329 175.0
HFD2_k127_7704650_9 glyoxalase III activity - - - 0.00000000000000000003145 91.0
HFD2_k127_7709201_0 regulation of microtubule-based process K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 475.0
HFD2_k127_7709201_1 late embryogenesis abundant protein - - - 0.000000000000000001681 96.0
HFD2_k127_7709201_2 PFAM DoxX K15977 - - 0.000003394 49.0
HFD2_k127_7709201_3 PFAM Peptidase M56, BlaR1 - - - 0.000006428 56.0
HFD2_k127_7717079_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K17722 - 1.3.1.1 0.000000000000000000000000000000000000000000000000005263 188.0
HFD2_k127_7717079_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000007254 154.0
HFD2_k127_7718042_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 518.0
HFD2_k127_7718042_1 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 424.0
HFD2_k127_7718042_2 4,6-dehydratase K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 383.0
HFD2_k127_7718042_3 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000007656 238.0
HFD2_k127_7718042_4 WxcM-like, C-terminal K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000002104 209.0
HFD2_k127_7718042_5 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000003201 213.0
HFD2_k127_7718042_6 Periplasmic protein involved in polysaccharide export - - - 0.00000000000000000000001872 111.0
HFD2_k127_7743602_0 DNA topoisomerase II activity K02469 - 5.99.1.3 6.571e-309 962.0
HFD2_k127_7743602_1 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000003687 215.0
HFD2_k127_7743602_2 Domain of unknown function (DUF4114) - - - 0.00000008931 60.0
HFD2_k127_774849_0 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000001345 194.0
HFD2_k127_774849_1 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000001282 170.0
HFD2_k127_774849_2 Methyltransferase K00587 - 2.1.1.100 0.000000000000000000000000000000001565 136.0
HFD2_k127_774849_3 COG1595 DNA-directed RNA polymerase specialized sigma K03088 - - 0.000000007313 64.0
HFD2_k127_7748989_0 PFAM Uncharacterised protein family UPF0182 K09118 - - 9.52e-204 668.0
HFD2_k127_7748989_1 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 422.0
HFD2_k127_7748989_2 EVE domain - - - 0.0000000000000000000000000000000000000000127 159.0
HFD2_k127_7748989_3 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.00000000000000000007914 98.0
HFD2_k127_7748989_4 saccharopine dehydrogenase activity K19064 - 1.4.1.18 0.00000000000001276 76.0
HFD2_k127_7748989_5 - - - - 0.00002005 54.0
HFD2_k127_7759202_0 L,D-transpeptidase catalytic domain K21470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003278 263.0
HFD2_k127_7759202_1 HI0933-like protein - - - 0.00000003965 65.0
HFD2_k127_7759202_2 Methyltransferase domain - - - 0.0000001368 63.0
HFD2_k127_7759202_3 Peptidase M15 - - - 0.000003045 57.0
HFD2_k127_7760029_0 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006625 256.0
HFD2_k127_7760029_1 transcriptional regulator, SARP family - - - 0.0000000004379 73.0
HFD2_k127_7803623_0 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000000000000000000000000000326 157.0
HFD2_k127_7803623_1 PKD domain containing protein - - - 0.00000000195 70.0
HFD2_k127_7803623_2 TadE-like protein - - - 0.00002591 50.0
HFD2_k127_780381_0 PFAM PHP domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000219 244.0
HFD2_k127_7805277_0 PilX N-terminal - - - 0.0006156 49.0
HFD2_k127_7811392_0 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 339.0
HFD2_k127_7811392_1 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002709 229.0
HFD2_k127_7811392_2 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000264 221.0
HFD2_k127_7811392_3 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000001676 210.0
HFD2_k127_7811392_5 PFAM blue (type 1) copper domain protein - - - 0.0000272 48.0
HFD2_k127_782240_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 464.0
HFD2_k127_782240_1 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001912 267.0
HFD2_k127_782240_2 Glucokinase K00845 - 2.7.1.2 0.0000000000001944 81.0
HFD2_k127_7838525_0 Protein of unknown function (DUF3738) K02172 - - 0.0000000000000000000000000000000000000000000000000000357 200.0
HFD2_k127_7838525_1 PFAM Nickel transport complex, NikM subunit, transmembrane K16915 - - 0.000000000000000000000000000000000000000002811 163.0
HFD2_k127_7838525_2 Protein of unknown function (DUF3738) - - - 0.000000000000000000000000000001436 124.0
HFD2_k127_7855872_0 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 553.0
HFD2_k127_7855872_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001545 280.0
HFD2_k127_7857219_0 Glycolate oxidase subunit K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 540.0
HFD2_k127_7857219_1 FAD linked oxidases, C-terminal domain K11472 - - 0.000000000000000000000000000000000000000000006181 188.0
HFD2_k127_7857219_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000001265 97.0
HFD2_k127_7857219_3 - - - - 0.00000000000001111 86.0
HFD2_k127_7871750_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 591.0
HFD2_k127_7871750_1 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000718 153.0
HFD2_k127_7871750_2 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.000741 49.0
HFD2_k127_7872338_0 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008104 310.0
HFD2_k127_7872338_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.0000000001013 64.0
HFD2_k127_7879613_0 ArgE DapE Acy1 family protein K01438,K01439 - 3.5.1.16,3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 545.0
HFD2_k127_7879613_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 398.0
HFD2_k127_7879613_2 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000929 222.0
HFD2_k127_7879613_3 PFAM CoA-binding domain protein K06929 - - 0.0000000000000000000000000000000000003334 150.0
HFD2_k127_7879613_4 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000001261 97.0
HFD2_k127_7879613_5 Predicted membrane protein (DUF2079) - - - 0.000000000157 74.0
HFD2_k127_7879613_6 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.0000007628 57.0
HFD2_k127_7879613_7 COG1664 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000095 55.0
HFD2_k127_7893014_0 cellulose binding K00505 - 1.14.18.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008364 397.0
HFD2_k127_7893014_1 helix_turn _helix lactose operon repressor K02529,K03435 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003833 276.0
HFD2_k127_7893014_2 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688 - 2.4.1.20 0.0000000000000000000000000000000000000000000000000000000000001562 228.0
HFD2_k127_7895454_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005054 409.0
HFD2_k127_7895454_1 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 338.0
HFD2_k127_7895454_2 Protein of unknown function (DUF512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004687 266.0
HFD2_k127_7895454_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000007862 160.0
HFD2_k127_7895454_4 helix_turn_helix, mercury resistance - - - 0.0000000000000000002845 98.0
HFD2_k127_7895454_5 dehydrogenase - - - 0.0000003526 53.0
HFD2_k127_7895454_6 Low affinity iron permease - - - 0.00007729 48.0
HFD2_k127_7899286_0 Fumarylacetoacetate (FAA) hydrolase family K16165 - 3.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000003678 246.0
HFD2_k127_7899286_1 PFAM Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000006528 244.0
HFD2_k127_7899286_2 Ser Thr phosphatase family protein K03547 - - 0.0000000000000000000000000000000000000000000000000000000000001833 226.0
HFD2_k127_7899286_3 AAA domain - - - 0.0000000000000000000000000473 117.0
HFD2_k127_7899286_4 Pfam:DUF955 - - - 0.00000004216 64.0
HFD2_k127_7899286_5 COG0457 FOG TPR repeat - - - 0.0003079 53.0
HFD2_k127_7899315_0 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000002686 244.0
HFD2_k127_7899315_1 phosphinothricin N-acetyltransferase activity K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000003193 211.0
HFD2_k127_7899315_2 (Rhomboid) family - - - 0.00000000000000000004505 91.0
HFD2_k127_7921485_0 Domain of unknown function DUF11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 467.0
HFD2_k127_7921485_1 COG2801 Transposase and inactivated derivatives K07497 - - 0.0000000000000000000000001505 109.0
HFD2_k127_7921485_2 COG2801 Transposase and inactivated derivatives K07497 - - 0.00000006263 54.0
HFD2_k127_7926257_0 C-terminal domain of 1-Cys peroxiredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 400.0
HFD2_k127_7926257_1 - - - - 0.00000000000000000003649 96.0
HFD2_k127_7926257_2 Phosphoglycerate mutase family - - - 0.00000000000000000007021 96.0
HFD2_k127_7926257_3 Peptidase M56 - - - 0.0000000000000000004936 93.0
HFD2_k127_7939896_0 type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000458 297.0
HFD2_k127_7939896_1 Pilus assembly protein, PilO K02664 - - 0.00000000001798 76.0
HFD2_k127_7939896_3 PFAM Fimbrial assembly family protein K02663 - - 0.000002407 57.0
HFD2_k127_7940306_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 534.0
HFD2_k127_7940306_1 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000001156 225.0
HFD2_k127_7940306_2 - - - - 0.0000000000000000000000000006897 113.0
HFD2_k127_7940306_3 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant K07025 - - 0.0000000000000000000000114 110.0
HFD2_k127_7940306_4 Tetratricopeptide repeat - - - 0.000000000003157 80.0
HFD2_k127_7942977_0 AcrB/AcrD/AcrF family K03296 - - 1.652e-317 1003.0
HFD2_k127_7949534_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 293.0
HFD2_k127_7949534_1 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004462 261.0
HFD2_k127_795595_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 580.0
HFD2_k127_795595_1 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 432.0
HFD2_k127_795595_2 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007563 376.0
HFD2_k127_795595_3 Molybdate ABC transporter K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001605 271.0
HFD2_k127_795595_4 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000003838 202.0
HFD2_k127_795595_5 cellulase activity - - - 0.0000000000000000005001 103.0
HFD2_k127_795595_6 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000002211 64.0
HFD2_k127_7963923_0 ABC transporter K02021,K06147,K06148,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009829 333.0
HFD2_k127_7964504_0 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000002122 189.0
HFD2_k127_7964504_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000005053 102.0
HFD2_k127_7964504_2 - - - - 0.0000005218 58.0
HFD2_k127_7984131_0 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.0000000000000000000000000001788 124.0
HFD2_k127_7984131_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000006466 55.0
HFD2_k127_7984131_2 DNA-binding protein - - - 0.000001183 52.0
HFD2_k127_8001078_0 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 456.0
HFD2_k127_8001078_1 Anti-anti sigma factor protein K17763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 292.0
HFD2_k127_8001078_2 Histidine kinase-like ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001638 281.0
HFD2_k127_8001078_3 PFAM Sulfate transporter antisigma-factor antagonist STAS K17762 - - 0.00000000000000000000000000000000000000000009262 162.0
HFD2_k127_8001078_4 Anti-sigma regulatory factor (Ser Thr protein kinase) K17752 - 2.7.11.1 0.0000000000000000000000000000000000003291 145.0
HFD2_k127_8025851_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 7.563e-206 652.0
HFD2_k127_8025851_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 501.0
HFD2_k127_8025851_2 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 344.0
HFD2_k127_8025851_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000524 223.0
HFD2_k127_8025851_4 Immune inhibitor A peptidase M6 - - - 0.000000000000000000000000000000000000000000000000004571 209.0
HFD2_k127_8025851_5 DNA internalization-related competence protein ComEC Rec2 K02238 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000003687 97.0
HFD2_k127_8025851_6 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000004941 70.0
HFD2_k127_8056778_0 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 8.191e-199 635.0
HFD2_k127_8056778_1 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 4.947e-194 617.0
HFD2_k127_8056778_10 ribonuclease BN K07058 - - 0.00000000000000000000000000009727 128.0
HFD2_k127_8056778_11 Yqey-like protein K09117 - - 0.0000000000000000000000000001238 123.0
HFD2_k127_8056778_12 OprF membrane domain K03286 - - 0.00000000007375 70.0
HFD2_k127_8056778_2 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 471.0
HFD2_k127_8056778_3 Belongs to the cysteine synthase cystathionine beta- synthase family K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 402.0
HFD2_k127_8056778_4 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 373.0
HFD2_k127_8056778_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000002528 250.0
HFD2_k127_8056778_6 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000005575 208.0
HFD2_k127_8056778_7 PFAM Appr-1-p processing domain protein - - - 0.00000000000000000000000000000000000000000000000007477 187.0
HFD2_k127_8056778_8 JAB/MPN domain - - - 0.0000000000000000000000000000000000000000009382 163.0
HFD2_k127_8056778_9 Periplasmic or secreted lipoprotein - - - 0.00000000000000000000000000004399 126.0
HFD2_k127_8070330_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.219e-295 919.0
HFD2_k127_8070330_1 endonuclease activity K07451 - - 0.00000000000000000003194 96.0
HFD2_k127_8088860_0 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000482 315.0
HFD2_k127_8088860_1 Hydrolase Family 16 - - - 0.000000000000000000000000000000000000114 160.0
HFD2_k127_8088860_2 Glycosyl hydrolase family 1 K05350 - 3.2.1.21 0.000000000000000000000000000000004074 128.0
HFD2_k127_8088860_3 Glycosyltransferase 36 associated - - - 0.00000000000000004649 83.0
HFD2_k127_8088860_4 extracellular matrix structural constituent - - - 0.000000001069 71.0
HFD2_k127_8088860_5 cellulose binding - - - 0.0000001953 64.0
HFD2_k127_8094797_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 484.0
HFD2_k127_8094797_1 PFAM aspartate glutamate uridylate kinase K12524 - 1.1.1.3,2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005121 469.0
HFD2_k127_8094797_2 GAF domain-containing protein K08968 - 1.8.4.14 0.000000000000000000000000000000000000000000000000000001431 196.0
HFD2_k127_8096419_0 ABC transporter K06147,K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 491.0
HFD2_k127_8096419_1 methyltransferase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000001706 183.0
HFD2_k127_8096419_2 COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein - - - 0.000000000000000000000000000000000000002632 159.0
HFD2_k127_80998_0 Belongs to the serpin family K13963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007229 358.0
HFD2_k127_80998_1 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000005389 269.0
HFD2_k127_80998_2 Transcriptional regulator, ArsR family - - - 0.0000000000000000000000000001088 117.0
HFD2_k127_8100996_0 N-acetylglucosaminylinositol deacetylase activity K22135 - - 0.00000000000000000000000001873 120.0
HFD2_k127_8100996_1 Fructosamine kinase - - - 0.0001109 53.0
HFD2_k127_8125767_0 Helix-hairpin-helix motif K02237 - - 0.00000000000000000000000000000000000000000000000000000001003 213.0
HFD2_k127_8125767_1 Belongs to the 5'-nucleotidase family K01081,K11751,K17224 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000000004387 149.0
HFD2_k127_8125767_2 long-chain fatty acid transport protein K06076 - - 0.0000000006733 72.0
HFD2_k127_8138549_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066 - 1.1.1.132,1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 482.0
HFD2_k127_8138549_1 Carbamoyltransferase C-terminus K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 409.0
HFD2_k127_8138549_2 Highly conserved protein containing a thioredoxin domain K20948 - - 0.000000000000000000000000000000000000000000000000000000000000002351 228.0
HFD2_k127_8138549_3 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000003935 217.0
HFD2_k127_8139531_0 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 476.0
HFD2_k127_8139531_1 PFAM Cytochrome b b6 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 404.0
HFD2_k127_8139531_2 Cytochrome b(C-terminal)/b6/petD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 374.0
HFD2_k127_8139531_3 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000000001682 199.0
HFD2_k127_8161858_0 - - - - 0.0000003852 64.0
HFD2_k127_8162765_0 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006285 462.0
HFD2_k127_8162765_1 Integral membrane protein TerC family K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 384.0
HFD2_k127_8162765_2 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008573 270.0
HFD2_k127_8162765_3 MobA-like NTP transferase domain K07141,K19190 - 1.1.1.328,2.7.7.76 0.0000323 51.0
HFD2_k127_8174687_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 295.0
HFD2_k127_8176330_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004012 298.0
HFD2_k127_8176330_1 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001336 226.0
HFD2_k127_8176330_2 metallopeptidase activity K01387,K01730,K20276 - 3.4.24.3,4.2.2.6 0.000000000002126 73.0
HFD2_k127_818043_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 491.0
HFD2_k127_818043_1 acetyltransferase - - - 0.0000000000000000000000000000000000000000005824 161.0
HFD2_k127_818043_2 Trypsin-like serine protease K01337 - 3.4.21.50 0.00000000000000000000000001887 126.0
HFD2_k127_818043_3 Bacterial Ig-like domain (group 1) - - - 0.0000000000006601 82.0
HFD2_k127_818043_4 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000002695 70.0
HFD2_k127_818134_0 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 454.0
HFD2_k127_818134_1 PFAM ATP-binding region ATPase domain protein K07709 - 2.7.13.3 0.000000000000000000000000000000000000000001009 164.0
HFD2_k127_8197908_0 - - - - 0.0000002027 63.0
HFD2_k127_8209285_0 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 354.0
HFD2_k127_8244337_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1309.0
HFD2_k127_8244337_1 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 444.0
HFD2_k127_8255011_0 PFAM NADH flavin oxidoreductase NADH oxidase K09461 - 1.14.13.40 1.087e-306 962.0
HFD2_k127_8255011_1 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 2.947e-221 699.0
HFD2_k127_8255011_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 473.0
HFD2_k127_8255011_3 Peptidase S9, prolyl oligopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 450.0
HFD2_k127_8255011_4 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 376.0
HFD2_k127_8255011_5 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019,K07535 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000002413 244.0
HFD2_k127_8255011_6 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009117,GO:0009150,GO:0009259,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019693,GO:0019752,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051186,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000003167 231.0
HFD2_k127_8255011_7 translation initiation inhibitor, yjgF family - - - 0.00000000000000000000000000000000005577 140.0
HFD2_k127_8271367_0 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000000000000000006452 218.0
HFD2_k127_8271367_1 BlaR1 peptidase M56 - - - 0.0000000000000000000000000000000000000000000000008245 199.0
HFD2_k127_8271367_2 Methicillin resistance protein - - - 0.00000000000000000000000004898 111.0
HFD2_k127_8271367_3 biopolymer transport protein - - - 0.00000000000000000000000009825 111.0
HFD2_k127_8271367_4 PFAM Biopolymer transport protein ExbD TolR - - - 0.000000000000000000000006737 110.0
HFD2_k127_8271367_5 Tetratricopeptide repeat - - - 0.000000001225 71.0
HFD2_k127_8271367_6 energy transducer activity K03832 - - 0.000000217 62.0
HFD2_k127_8291605_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.146e-223 711.0
HFD2_k127_8291605_1 PFAM Divergent PAP2 family K09775 - - 0.00000000000000000000000000000000003952 138.0
HFD2_k127_8295996_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 1.875e-219 704.0
HFD2_k127_8295996_1 Tetratricopeptide repeat - - - 0.000000000000002147 90.0
HFD2_k127_8300929_0 Domains REC, sigma54 interaction, HTH8 K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 388.0
HFD2_k127_8300929_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000003798 205.0
HFD2_k127_8311596_0 Malate synthase K01638 - 2.3.3.9 4.295e-240 747.0
HFD2_k127_8311596_1 Type II/IV secretion system protein K02669 - - 0.00000000000000004103 81.0
HFD2_k127_8333889_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.0 1122.0
HFD2_k127_8333889_1 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008147 496.0
HFD2_k127_8333889_2 metallophosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 325.0
HFD2_k127_8333889_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000002392 220.0
HFD2_k127_8333889_4 DsrE/DsrF/DrsH-like family - - - 0.00000000004978 68.0
HFD2_k127_8341561_0 FHA domain protein - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 - 0.00000000000000041 83.0
HFD2_k127_8341561_1 Caspase domain - - - 0.000000000000001748 89.0
HFD2_k127_8341561_2 Clp amino terminal domain, pathogenicity island component - - - 0.00000000783 64.0
HFD2_k127_835996_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000009199 205.0
HFD2_k127_835996_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000589 187.0
HFD2_k127_835996_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000001077 173.0
HFD2_k127_835996_3 Uncharacterized conserved protein (DUF2304) K09153 - - 0.00000000002605 74.0
HFD2_k127_8361916_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 537.0
HFD2_k127_8361916_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 347.0
HFD2_k127_8361916_2 Aspartyl/Asparaginyl beta-hydroxylase - - - 0.000005935 59.0
HFD2_k127_836593_0 TonB-dependent Receptor Plug Domain K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 391.0
HFD2_k127_8366209_0 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000000006162 192.0
HFD2_k127_8366209_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000000000000000000000000000000002204 176.0
HFD2_k127_8366209_2 Belongs to the glycosyl hydrolase 13 family K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.0000000000000000000000000000000003047 145.0
HFD2_k127_8368836_0 Tricorn protease homolog K08676 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 572.0
HFD2_k127_8368836_1 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.0000000008337 59.0
HFD2_k127_8374626_0 Prokaryotic cytochrome b561 - - - 0.0 1134.0
HFD2_k127_8374626_1 NapC/NirT cytochrome c family, N-terminal region - GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 420.0
HFD2_k127_8374626_2 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000003881 122.0
HFD2_k127_8374626_3 heat shock protein binding - - - 0.0000000001951 72.0
HFD2_k127_8374626_4 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000001384 63.0
HFD2_k127_8374626_5 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.0000002367 62.0
HFD2_k127_8374706_0 Anthranilate synthase component I, N terminal region K01657,K01665,K13950 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 390.0
HFD2_k127_8374706_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005574 287.0
HFD2_k127_8374706_2 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002815 273.0
HFD2_k127_8374706_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000002423 202.0
HFD2_k127_8374706_4 B12 binding domain - - - 0.00000000000000000000000000002948 129.0
HFD2_k127_8374706_5 Redoxin - - - 0.000000000000000000001565 98.0
HFD2_k127_8374706_6 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 - 3.5.4.4 0.0000000000000002808 87.0
HFD2_k127_8374706_7 Redoxin - - - 0.00001897 49.0
HFD2_k127_8374706_8 Tetratricopeptide repeat - - - 0.0001915 51.0
HFD2_k127_841028_0 Domain of unknown function (DUF1998) K06877 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 605.0
HFD2_k127_841028_1 PFAM Cys Met metabolism K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 355.0
HFD2_k127_841028_2 RNase_H superfamily K07502 - - 0.000000000000000000000000000000931 134.0
HFD2_k127_841028_3 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000001302 98.0
HFD2_k127_8410639_0 High confidence in function and specificity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 579.0
HFD2_k127_8410639_1 Major facilitator Superfamily K08162,K08226,K16211 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 512.0
HFD2_k127_8410639_10 Crossover junction endodeoxyribonuclease RuvC K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000004703 153.0
HFD2_k127_8410639_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000001271 148.0
HFD2_k127_8410639_2 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 347.0
HFD2_k127_8410639_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 354.0
HFD2_k127_8410639_4 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005248 276.0
HFD2_k127_8410639_5 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005315 265.0
HFD2_k127_8410639_6 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000266 261.0
HFD2_k127_8410639_7 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000000000000002035 177.0
HFD2_k127_8410639_8 AAA domain - - - 0.00000000000000000000000000000000000000000091 161.0
HFD2_k127_8410639_9 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000008096 165.0
HFD2_k127_8429978_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 378.0
HFD2_k127_8429978_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.0000000000000000000000000000000000000000000147 173.0
HFD2_k127_8430783_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 531.0
HFD2_k127_8430783_1 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 363.0
HFD2_k127_84326_0 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007392 298.0
HFD2_k127_84326_1 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000004568 114.0
HFD2_k127_8433423_0 Cytochrome c K00373,K00405,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.000000000000000000000000000000000000000000000003379 196.0
HFD2_k127_8433423_1 Cytochrome c - - - 0.00000000001984 78.0
HFD2_k127_8433423_2 NosL K19342 - - 0.0000000003175 70.0
HFD2_k127_8433423_3 - K19341 - - 0.00004286 49.0
HFD2_k127_8445132_0 Sterol carrier protein domain - - - 0.00000000000000000000000000000000000000000000000000000000659 207.0
HFD2_k127_8445132_1 Transport permease protein - - - 0.000000000000000000000000000000000001333 145.0
HFD2_k127_8448612_0 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 400.0
HFD2_k127_8448612_1 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009128 293.0
HFD2_k127_8448612_2 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.0000000000000000000000000000000000001329 149.0
HFD2_k127_8448612_3 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000005362 72.0
HFD2_k127_8448713_0 Helix-hairpin-helix motif K02337 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008294 312.0
HFD2_k127_8448713_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000004353 180.0
HFD2_k127_8448713_3 Fibronectin type 3 domain - - - 0.00001061 54.0
HFD2_k127_8454129_0 - - - - 0.00005446 55.0
HFD2_k127_8463505_0 Amidohydrolase family - - - 6.123e-298 951.0
HFD2_k127_8463505_1 Phospholipase D. Active site motifs. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 357.0
HFD2_k127_8468486_0 Glycosyltransferase 36 associated - - - 2.253e-290 912.0
HFD2_k127_8468486_1 coagulation factor 5 8 type - - - 5.623e-284 908.0
HFD2_k127_8468486_2 COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 572.0
HFD2_k127_8468486_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000499 118.0
HFD2_k127_848129_0 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 629.0
HFD2_k127_848129_1 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 488.0
HFD2_k127_848129_2 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K03325,K03741,K03892,K18701 - 1.20.4.1,2.8.4.2,3.1.3.48 0.0000000000000000000000000000000000000005205 155.0
HFD2_k127_848129_3 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000002256 132.0
HFD2_k127_8482178_0 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07713,K07714,K19641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 482.0
HFD2_k127_8482178_1 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 331.0
HFD2_k127_8482178_2 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001359 269.0
HFD2_k127_8491904_0 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 596.0
HFD2_k127_8491904_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 398.0
HFD2_k127_8491904_10 long-chain fatty acid transporting porin activity - - - 0.0000000001018 69.0
HFD2_k127_8491904_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001151 288.0
HFD2_k127_8491904_3 Permease YjgP YjgQ K11720 - - 0.00000000000000000000000000000000000000000000000000000007836 212.0
HFD2_k127_8491904_4 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000001355 160.0
HFD2_k127_8491904_5 Belongs to the ComB family K05979 - 3.1.3.71 0.00000000000000000000000000000000000000002342 165.0
HFD2_k127_8491904_6 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K00627,K01571,K02160 - 2.3.1.12,4.1.1.3 0.0000000000000000000000000000000000000002022 154.0
HFD2_k127_8491904_7 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000007073 149.0
HFD2_k127_8491904_8 Permease YjgP YjgQ family protein K07091,K11720 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000004349 124.0
HFD2_k127_8491904_9 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000001467 132.0
HFD2_k127_8494853_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008853 339.0
HFD2_k127_8494853_1 PFAM Formylglycine-generating sulfatase enzyme K12132,K18912 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0019439,GO:0019752,GO:0034641,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0055114,GO:0071704,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.14.99.50,2.7.11.1 0.00000000000000000000000000000000000000000001135 181.0
HFD2_k127_8494853_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000248 117.0
HFD2_k127_8494853_3 - - - - 0.00000000007695 76.0
HFD2_k127_851401_0 Elongation factor SelB winged helix 3 K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326 443.0
HFD2_k127_851401_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000005473 145.0
HFD2_k127_851401_2 AntiSigma factor - - - 0.000005234 56.0
HFD2_k127_8524422_0 - - - - 0.0000000000000000000000000000000000000000000000004589 199.0
HFD2_k127_8524422_1 domain protein - - - 0.00000000000000000000000000000000009298 144.0
HFD2_k127_8524422_2 Thiol-disulfide oxidoreductase DCC - - - 0.00000000000000000000000000000005455 130.0
HFD2_k127_8524422_3 domain protein - - - 0.00000000000000000000000000001697 130.0
HFD2_k127_8524422_4 6-phosphogluconolactonase activity - - - 0.000000000000000000000004742 119.0
HFD2_k127_8524422_5 LytTr DNA-binding domain K02477 - - 0.0000000239 55.0
HFD2_k127_8527749_0 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K11991 GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.1,3.5.4.33 0.0000000000000000000000000000000000000000000000124 177.0
HFD2_k127_8527749_1 PFAM thioesterase superfamily K12073 - 3.1.2.28 0.000000000000000000003441 100.0
HFD2_k127_8527749_2 PFAM Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.000006358 59.0
HFD2_k127_8529547_0 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 396.0
HFD2_k127_8529547_1 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 312.0
HFD2_k127_8529547_2 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009379 243.0
HFD2_k127_8529547_3 photosystem I assembly BtpA K06971 - - 0.00000000000000000000000000000000000000000000000000000000000000000001633 250.0
HFD2_k127_8529547_4 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000007326 235.0
HFD2_k127_8529547_5 TIGRFAM 3-oxoacyl-(acyl-carrier-protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000757 181.0
HFD2_k127_8529547_6 Putative esterase - - - 0.00000000000000005013 81.0
HFD2_k127_8532076_0 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 605.0
HFD2_k127_8532076_1 SAM (And some other nucleotide) binding motif - - - 0.0000000000000000000000000000000000000000000000000000000000000001966 229.0
HFD2_k127_8549325_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 571.0
HFD2_k127_8549325_1 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000002536 174.0
HFD2_k127_8554818_0 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008852 499.0
HFD2_k127_8554818_1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 377.0
HFD2_k127_8554818_2 methyltransferase - - - 0.000000000000000000000000000000000000000000002541 177.0
HFD2_k127_8554818_3 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000001312 127.0
HFD2_k127_8554818_4 Tellurite resistance protein TerB - - - 0.000000000000001584 86.0
HFD2_k127_8556201_0 type VI secretion system effector K11903 - - 0.000000000000000000000000000000000000000000000003066 179.0
HFD2_k127_8556201_1 metal cluster binding - - - 0.000000000000000000000000000000000000000005158 165.0
HFD2_k127_8556201_2 SPTR Transglutaminase domain protein - - - 0.0006794 49.0
HFD2_k127_856184_0 PFAM amidohydrolase K01464 - 3.5.2.2 2.603e-195 623.0
HFD2_k127_856184_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000004268 205.0
HFD2_k127_8578332_0 Isocitrate/isopropylmalate dehydrogenase - - - 2.482e-232 728.0
HFD2_k127_8578332_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 342.0
HFD2_k127_8578332_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 346.0
HFD2_k127_8578332_3 SdpI/YhfL protein family - - - 0.000000000000000000000000000000000000000000000000000000000000005026 223.0
HFD2_k127_8578332_4 PAP2 superfamily - - - 0.00001088 51.0
HFD2_k127_8580518_0 Condensation domain - - - 0.0 1510.0
HFD2_k127_8580518_1 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 428.0
HFD2_k127_8580518_2 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 358.0
HFD2_k127_8580518_3 - - - - 0.000000000000000000000000000000000566 146.0
HFD2_k127_8580518_4 - - - - 0.00000000000000000007727 91.0
HFD2_k127_8580518_6 amine dehydrogenase activity - - - 0.000000000000000001294 99.0
HFD2_k127_8610291_0 Bacterial regulatory protein, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005633 276.0
HFD2_k127_8610291_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K17105 - 2.5.1.39,2.5.1.42 0.00000000000000000000009556 104.0
HFD2_k127_8610291_2 - - - - 0.0000006207 59.0
HFD2_k127_8629220_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1347.0
HFD2_k127_8629220_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009013 595.0
HFD2_k127_8629220_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 340.0
HFD2_k127_8647715_0 thiosulfate sulfurtransferase activity K00406,K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000002015 188.0
HFD2_k127_8647715_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000001888 175.0
HFD2_k127_8655635_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 439.0
HFD2_k127_8660146_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573,K12585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 329.0
HFD2_k127_8660146_1 - - - - 0.000000000000000000000000000000000001561 144.0
HFD2_k127_8660146_2 - - - - 0.0000000000000000000000000000000001885 145.0
HFD2_k127_8671107_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 489.0
HFD2_k127_8671107_1 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 340.0
HFD2_k127_8671107_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000005748 63.0
HFD2_k127_8673959_0 bacterial-type flagellum-dependent cell motility - - - 0.000000000006116 76.0
HFD2_k127_8673959_1 Evidence 5 No homology to any previously reported sequences - - - 0.000000009374 67.0
HFD2_k127_8677446_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02372,K02535,K13599,K16363 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 3.5.1.108,4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 437.0
HFD2_k127_8677446_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000001848 139.0
HFD2_k127_8677446_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000009868 53.0
HFD2_k127_8683257_0 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000001305 236.0
HFD2_k127_8683257_1 ATPase activity - - - 0.0000000000000000000000005201 119.0
HFD2_k127_8683257_2 DNA-templated transcription, termination K03628 - - 0.0000000001237 66.0
HFD2_k127_8697699_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 396.0
HFD2_k127_8697699_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003628 296.0
HFD2_k127_8697699_2 Putative exonuclease SbcCD, C subunit K03546 - - 0.000000000000000000000000000000000000000000000000000000000002057 218.0
HFD2_k127_8697699_3 CHAT domain - - - 0.000000000000000000000000000001782 138.0
HFD2_k127_8697699_4 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000001229 129.0
HFD2_k127_8697699_5 ChrR Cupin-like domain - - - 0.0003323 51.0
HFD2_k127_8699858_0 Glucose / Sorbosone dehydrogenase K21430 - - 0.00000000000000000000000000000000000000000000000000000000000001672 233.0
HFD2_k127_8699858_1 amine dehydrogenase activity - - - 0.000000001182 68.0
HFD2_k127_8715614_0 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 374.0
HFD2_k127_8715614_1 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.000000000000000000000001728 106.0
HFD2_k127_8718011_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008473 351.0
HFD2_k127_8718011_1 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 325.0
HFD2_k127_8718011_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000008518 54.0
HFD2_k127_8742697_0 Sterol carrier protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 359.0
HFD2_k127_8742697_1 Mycolic acid cyclopropane synthetase - - - 0.000000000000000002029 97.0
HFD2_k127_8742697_2 Zinc metalloprotease (Elastase) - - - 0.00000000000000004114 92.0
HFD2_k127_8742697_3 Ion channel - - - 0.00000000000000006098 83.0
HFD2_k127_8742697_4 Acetyltransferase (GNAT) family - - - 0.000000002297 63.0
HFD2_k127_8753772_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 347.0
HFD2_k127_8753772_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000001466 171.0
HFD2_k127_88557_0 aconitate hydratase K01681 - 4.2.1.3 4.226e-233 731.0
HFD2_k127_88557_1 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 626.0
HFD2_k127_88557_2 - - - - 0.0000000000000000000000000000000000000000002811 167.0
HFD2_k127_88557_3 CAAX protease self-immunity K07052 - - 0.0000000000000000007444 93.0
HFD2_k127_898090_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009945 568.0
HFD2_k127_898090_1 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000832 209.0
HFD2_k127_905137_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009708 505.0
HFD2_k127_905137_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 464.0
HFD2_k127_905137_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006438 401.0
HFD2_k127_905137_3 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 309.0
HFD2_k127_905137_4 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000001979 161.0
HFD2_k127_913698_0 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 410.0
HFD2_k127_913698_1 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000002648 115.0
HFD2_k127_926503_0 PSP1 C-terminal conserved region - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000005773 229.0
HFD2_k127_926503_1 dna polymerase iii K02341 - 2.7.7.7 0.00000000000000002792 92.0
HFD2_k127_927766_0 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000005465 203.0
HFD2_k127_927766_1 Domain of unknown function (DUF1848) - - - 0.00000000000000000000000000000001105 131.0
HFD2_k127_927766_2 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000000000000002319 113.0
HFD2_k127_933325_1 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 610.0
HFD2_k127_933325_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 431.0
HFD2_k127_933325_3 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 305.0
HFD2_k127_933325_4 Glycosyl hydrolase family 70 K01142,K01176 - 3.1.11.2,3.2.1.1 0.000000006807 68.0
HFD2_k127_964012_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.0 1067.0
HFD2_k127_973858_0 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 379.0
HFD2_k127_973858_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 304.0
HFD2_k127_973858_2 regulation of canonical Wnt signaling pathway involved in osteoblast differentiation K01691 - - 0.000006082 55.0
HFD2_k127_975016_0 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 394.0
HFD2_k127_975016_1 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001342 304.0
HFD2_k127_975016_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000001312 217.0
HFD2_k127_975016_3 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000001099 200.0
HFD2_k127_975016_4 PFAM DivIVA K04074 - - 0.000000000000000000000169 105.0
HFD2_k127_975688_0 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 480.0
HFD2_k127_975688_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 310.0
HFD2_k127_975688_2 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000112 233.0
HFD2_k127_989438_0 Multicopper oxidase K06324 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 498.0
HFD2_k127_989438_1 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000008176 170.0
HFD2_k127_989438_2 cellulose binding - - - 0.00000000000000000000004634 105.0
HFD2_k127_989438_3 - - - - 0.0000000000002446 83.0
HFD2_k127_989438_4 PFAM Uncharacterised BCR, COG1649 K01186,K01197,K05988,K11931,K18197 - 3.2.1.11,3.2.1.18,3.2.1.35,4.2.2.23 0.0000000000008832 75.0
HFD2_k127_989438_5 peroxiredoxin activity - - - 0.00004045 52.0
HFD2_k127_991078_0 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000001913 222.0
HFD2_k127_991078_1 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.0000000000000000000000000000000000000000000000000005914 188.0
HFD2_k127_991078_2 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000003264 194.0