logo

Overview

ID MAG01649
Name HFD2_bin.38
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Polarisedimenticolia
Order Gp22-AA2
Family AA152
Genus DASYRE01
Species
Assembly information
Completeness (%) 69.96
Contamination (%) 1.89
GC content (%) 67.0
N50 (bp) 4,077
Genome size (bp) 2,954,132

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2693

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_1007748_0 Metallo-beta-lactamase superfamily K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001296 262.0
HFD2_k127_1007748_1 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000009276 233.0
HFD2_k127_1007748_2 bacterial (prokaryotic) histone like domain K03530 - - 0.00000000000000000000000000004567 118.0
HFD2_k127_1007748_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000007737 96.0
HFD2_k127_1007748_4 PFAM PEGA domain - - - 0.000008563 57.0
HFD2_k127_100801_0 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 424.0
HFD2_k127_100801_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005497 347.0
HFD2_k127_100801_2 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 340.0
HFD2_k127_100801_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000000000001844 176.0
HFD2_k127_100801_4 Tetratricopeptide repeat - - - 0.000000000000003732 88.0
HFD2_k127_1010974_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000001722 208.0
HFD2_k127_1010974_1 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000003502 133.0
HFD2_k127_1010974_2 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000002609 111.0
HFD2_k127_1010974_3 CarboxypepD_reg-like domain - - - 0.00000000000000007963 95.0
HFD2_k127_1027432_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000415 144.0
HFD2_k127_1039060_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005479 356.0
HFD2_k127_1039060_1 Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - 0.00000000000000000000000000000000000000000000000000000000000000000002204 238.0
HFD2_k127_1039060_2 Mediates zinc uptake. May also transport other divalent cations K07238 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000001573 107.0
HFD2_k127_1040325_0 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 412.0
HFD2_k127_1040325_1 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 360.0
HFD2_k127_1040325_2 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 318.0
HFD2_k127_1042504_0 Pkd domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008123 420.0
HFD2_k127_1046774_0 denitrification pathway K02569,K15876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 378.0
HFD2_k127_1046774_1 Cytochrome c554 and c-prime K03620 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000495 280.0
HFD2_k127_1046774_2 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000007851 237.0
HFD2_k127_1046774_3 Cytochrome b/b6/petB K00412,K03888 - - 0.000000000000000000000000000000000000000000000000004245 196.0
HFD2_k127_1046774_4 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.00000000000000001231 89.0
HFD2_k127_1046774_5 Sigma factor PP2C-like phosphatases - - - 0.0000000000000007366 79.0
HFD2_k127_1046923_0 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 406.0
HFD2_k127_1046923_1 amino acid carrier protein K03310 - - 0.000000000000000000000002025 115.0
HFD2_k127_1047821_0 Angiotensin-converting enzyme K01283 - 3.4.15.1 3.884e-206 662.0
HFD2_k127_1047821_1 SNARE associated Golgi protein K03975,K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009312 268.0
HFD2_k127_1047821_2 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000006187 89.0
HFD2_k127_1048032_0 DNA polymerase K02347 - - 2.501e-201 642.0
HFD2_k127_1048032_1 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 484.0
HFD2_k127_1048032_2 Domain of unknown function (DUF1802) - - - 0.000000000000000000000000002254 118.0
HFD2_k127_1048032_3 cytidine deaminase K01489 - 3.5.4.5 0.00001059 53.0
HFD2_k127_1072212_0 Major facilitator superfamily K05820 - - 0.0000000000000000000000006867 115.0
HFD2_k127_1072212_1 histidine kinase A domain protein K02482 - 2.7.13.3 0.000000000000000000005109 106.0
HFD2_k127_1084379_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007299 364.0
HFD2_k127_1084379_1 metallophosphoesterase K07096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 345.0
HFD2_k127_1084379_2 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 323.0
HFD2_k127_1086762_0 Ftsk_gamma K03466 - - 4.622e-268 848.0
HFD2_k127_1086762_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 424.0
HFD2_k127_1101332_0 COG1063 Threonine dehydrogenase and related Zn-dependent K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000004396 159.0
HFD2_k127_1101332_1 Sigma-70, region 4 K03088 - - 0.0000000000000000000000001249 119.0
HFD2_k127_1101332_2 - - - - 0.000009597 57.0
HFD2_k127_1117878_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 334.0
HFD2_k127_1117878_1 PFAM ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007168 308.0
HFD2_k127_1118190_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001244 286.0
HFD2_k127_1118190_1 Nucleoside recognition - - - 0.0000000000000000000000002815 111.0
HFD2_k127_1118190_2 ferrous iron transmembrane transporter activity - - - 0.00000000000000001821 89.0
HFD2_k127_1118190_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00001807 54.0
HFD2_k127_1129514_0 Domain of unknown function (DUF4162) K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 323.0
HFD2_k127_1129514_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 305.0
HFD2_k127_1129514_2 NADH dehydrogenase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004115 285.0
HFD2_k127_1129514_3 Domain of Unknown Function (DUF1259) - - - 0.000000000000000000000000000000000000000000000000000000000001553 221.0
HFD2_k127_1129514_4 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000000000004152 211.0
HFD2_k127_1129514_5 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000000000000009574 216.0
HFD2_k127_1129514_6 Protein of unknown function (DUF1579) - - - 0.000000000000000000000000000000000000002493 155.0
HFD2_k127_1129514_7 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000212 67.0
HFD2_k127_1129514_8 Peptidase MA superfamily - - - 0.0002043 53.0
HFD2_k127_1142091_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 626.0
HFD2_k127_1142091_1 response regulator K07712 - - 0.0000000000000000000000000000000003394 138.0
HFD2_k127_1142091_2 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000003223 103.0
HFD2_k127_1142091_3 Integral membrane sensor signal transduction histidine kinase K02482 - 2.7.13.3 0.000000000000000009071 96.0
HFD2_k127_1142091_4 TPR repeat - - - 0.00000000000002011 86.0
HFD2_k127_1142091_5 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.00000000008673 70.0
HFD2_k127_114444_0 Tricorn protease C1 domain K08676 - - 2e-323 1026.0
HFD2_k127_1147949_0 Belongs to the peptidase S8 family K17734 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 340.0
HFD2_k127_1147949_1 belongs to the thioredoxin family K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000133 285.0
HFD2_k127_1147949_2 Glycosyltransferase like family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003773 255.0
HFD2_k127_1147949_3 similarity to GB CAH39666.1 - - - 0.000000000000000000000000000000000000000000000000000005923 201.0
HFD2_k127_1147949_4 long-chain fatty acid transporting porin activity - - - 0.00000000000000000002279 104.0
HFD2_k127_1147949_5 alpha beta - - - 0.0000000000000000008612 102.0
HFD2_k127_1147949_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000001726 64.0
HFD2_k127_1154246_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 559.0
HFD2_k127_1154246_2 - - - - 0.00000001195 59.0
HFD2_k127_1156817_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 1.004e-292 911.0
HFD2_k127_1156817_1 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 562.0
HFD2_k127_1156817_2 Sodium Bile acid symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 499.0
HFD2_k127_1156817_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 444.0
HFD2_k127_1156817_4 PFAM permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002012 297.0
HFD2_k127_1156817_5 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000001721 129.0
HFD2_k127_1156859_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 381.0
HFD2_k127_1156859_1 MraW methylase family K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000002229 206.0
HFD2_k127_1156859_2 Evidence 5 No homology to any previously reported sequences - - - 0.000000000003184 72.0
HFD2_k127_1164370_0 Pyridine nucleotide-disulphide oxidoreductase - - - 9.96e-227 716.0
HFD2_k127_1188531_0 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 307.0
HFD2_k127_1188531_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000161 254.0
HFD2_k127_1188531_2 Domain of unknown function (DUF4440) - - - 0.000002558 56.0
HFD2_k127_1193950_0 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 612.0
HFD2_k127_1193950_1 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.00000000000000000000000000000000004971 138.0
HFD2_k127_1194221_0 SpoIVB peptidase S55 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 344.0
HFD2_k127_1194221_1 CBS domain-containing protein K03699 - - 0.00000000000000000000001457 102.0
HFD2_k127_1196643_0 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008334 437.0
HFD2_k127_1196643_1 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 400.0
HFD2_k127_1196643_2 efflux transmembrane transporter activity K12340 - - 0.00000000000000000000000000000000000000001365 169.0
HFD2_k127_1196643_3 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.00000002672 55.0
HFD2_k127_1200019_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000009315 133.0
HFD2_k127_1200019_1 Thioredoxin-like K02199 - - 0.0001466 53.0
HFD2_k127_1200019_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0005076 46.0
HFD2_k127_1205809_0 arylsulfatase activity - - - 0.00000000000000000000000000000000000000001905 171.0
HFD2_k127_1208785_0 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 543.0
HFD2_k127_1208785_1 Beta-Casp domain K07576,K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 445.0
HFD2_k127_1208785_2 Peptidase S46 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 299.0
HFD2_k127_1208785_3 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 291.0
HFD2_k127_1208785_4 C-terminal AAA-associated domain K02049 - - 0.000000000000000000000000000004554 125.0
HFD2_k127_1208785_5 - - - - 0.00000000000000000000000000001643 120.0
HFD2_k127_1208785_6 AMP binding - - - 0.0000000000000000005958 95.0
HFD2_k127_1208785_7 glycosyl transferase, family 39 - - - 0.0000004717 55.0
HFD2_k127_1215064_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 312.0
HFD2_k127_1215748_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000006086 155.0
HFD2_k127_1221320_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009011 297.0
HFD2_k127_1221320_1 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000002836 118.0
HFD2_k127_1221320_2 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000008322 121.0
HFD2_k127_1221320_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000173 47.0
HFD2_k127_124809_0 Domain of unknown function (DUF1998) K02336,K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005788 551.0
HFD2_k127_124809_1 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000009924 91.0
HFD2_k127_1254283_0 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008225 482.0
HFD2_k127_1254283_1 COG3264 Small-conductance mechanosensitive channel K22051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 358.0
HFD2_k127_1254283_2 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007183 309.0
HFD2_k127_1254283_3 Porin subfamily - - - 0.0000000000000000000000000000000000000000000000105 190.0
HFD2_k127_1283432_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 558.0
HFD2_k127_1283432_1 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009889 496.0
HFD2_k127_1283432_2 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 0.00000000000000000000000000000000000000000000000000000000000001974 225.0
HFD2_k127_1283432_3 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000924 196.0
HFD2_k127_1283432_4 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000000000268 159.0
HFD2_k127_1283432_5 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.000000000000000000000000000009373 122.0
HFD2_k127_1283432_6 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000002126 132.0
HFD2_k127_1283432_7 Tetratricopeptide repeat - - - 0.000000000000000008194 96.0
HFD2_k127_1290946_0 ABC transporter K02049,K15555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000065 274.0
HFD2_k127_1290946_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006552 251.0
HFD2_k127_1290946_2 NMT1-like family K02051 - - 0.000000000000000000000000000000000000001399 152.0
HFD2_k127_1290946_3 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.000000000000000000000000000006657 134.0
HFD2_k127_1290946_4 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000387 104.0
HFD2_k127_1291339_0 deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000002046 226.0
HFD2_k127_1291339_1 peptidyl-prolyl cis-trans isomerase K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000005692 183.0
HFD2_k127_1291339_2 oligoendopeptidase F - - - 0.000001864 56.0
HFD2_k127_1292098_0 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 424.0
HFD2_k127_1292098_1 TIGRFAM small redox-active disulfide protein 2 - - - 0.0000000000005094 74.0
HFD2_k127_1296782_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 5.337e-287 896.0
HFD2_k127_1296782_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000004106 191.0
HFD2_k127_1300946_0 Saccharopine dehydrogenase C-terminal domain K00293 - 1.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 370.0
HFD2_k127_1300946_1 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000004571 216.0
HFD2_k127_130793_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009414 314.0
HFD2_k127_130793_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000003747 75.0
HFD2_k127_1310855_0 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000913 301.0
HFD2_k127_1310855_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000001704 226.0
HFD2_k127_1310855_2 methyltransferase activity - - - 0.0003366 51.0
HFD2_k127_1338268_0 Glutathione peroxidase K02199 - - 0.0000000000000000000000004894 111.0
HFD2_k127_1338268_1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase - - - 0.00000000001591 71.0
HFD2_k127_1338268_2 Belongs to the UPF0637 family - - - 0.00004809 54.0
HFD2_k127_1355810_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 574.0
HFD2_k127_1355810_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 - 5.4.2.8 0.00000004434 59.0
HFD2_k127_1356510_0 response regulator receiver K07714,K10943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 436.0
HFD2_k127_1356510_1 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000006003 233.0
HFD2_k127_1356510_2 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000002637 195.0
HFD2_k127_1356510_3 SWI complex, BAF60b domains - - - 0.0000000000000000000000000000000002935 134.0
HFD2_k127_1358275_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 312.0
HFD2_k127_1358275_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000002291 187.0
HFD2_k127_135845_0 Peptidase family S51 K05995 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 297.0
HFD2_k127_135845_1 B3/4 domain K04567 - 6.1.1.6 0.000000000000000000000000000000000003427 147.0
HFD2_k127_135845_2 - - - - 0.0000000000000000000000000000001427 132.0
HFD2_k127_135845_3 - - - - 0.000000000000005288 83.0
HFD2_k127_1360840_0 B12 binding domain - - - 3.555e-200 629.0
HFD2_k127_1360840_1 Sulfatase - - - 0.000000000001865 70.0
HFD2_k127_1370361_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002381 277.0
HFD2_k127_1370361_1 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000002349 160.0
HFD2_k127_1370361_2 - - - - 0.00000000000000000000000000008729 123.0
HFD2_k127_1370361_3 - - - - 0.0003691 51.0
HFD2_k127_1381707_0 ABC-type uncharacterized transport system K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003241 278.0
HFD2_k127_1381707_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000008634 184.0
HFD2_k127_1381707_2 Domain of unknown function (DUF4340) - - - 0.000000000001965 80.0
HFD2_k127_1381707_3 ATPase activity K01990,K09697 - 3.6.3.7 0.0005623 44.0
HFD2_k127_1388805_0 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007792 306.0
HFD2_k127_1388805_1 Tellurite resistance protein TerB - - - 0.0000000000000000000000000001726 117.0
HFD2_k127_1408940_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008967 293.0
HFD2_k127_1408940_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007023 257.0
HFD2_k127_1408940_2 spore germination K07790 - - 0.000000000000000000000000000000000000000000000000006719 192.0
HFD2_k127_1408940_3 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000005625 186.0
HFD2_k127_1408940_4 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.0000000000000000000000000000000000000000000000004119 187.0
HFD2_k127_1408940_5 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000001578 174.0
HFD2_k127_1408940_6 - K01992,K19341 - - 0.0000000000000000000000000000000000007859 151.0
HFD2_k127_1408940_7 - - - - 0.000009551 59.0
HFD2_k127_1424486_0 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 486.0
HFD2_k127_1424486_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975,K01214 - 2.7.7.27,3.2.1.68 0.0000000000000000000000000000000000000000000000000000000000000005004 228.0
HFD2_k127_1424486_2 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000141 136.0
HFD2_k127_1424486_3 Metallo-peptidase family M12B Reprolysin-like - - - 0.00000000000000000000000001329 126.0
HFD2_k127_1431623_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009867 274.0
HFD2_k127_1431623_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000104 235.0
HFD2_k127_1431623_2 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.0000000000000000000000000000000000000000000000000000000000000006046 226.0
HFD2_k127_1431623_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000008944 201.0
HFD2_k127_1431623_4 domain, Protein - - - 0.00000000000000000000000000000000000000000000000277 196.0
HFD2_k127_1431623_5 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000002477 81.0
HFD2_k127_1445410_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 9.852e-214 668.0
HFD2_k127_1445410_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 434.0
HFD2_k127_1445410_2 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 313.0
HFD2_k127_1445410_3 Protein of unknown function (DUF1385) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 291.0
HFD2_k127_1445410_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000000000001474 223.0
HFD2_k127_1445410_5 Binds the 23S rRNA K02909 - - 0.000000000000000000000000002573 112.0
HFD2_k127_1445410_6 Tetratricopeptide repeat - - - 0.000006938 57.0
HFD2_k127_144743_0 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 6.178e-220 701.0
HFD2_k127_144743_1 benzoyl-CoA oxygenase K15512 - 1.14.13.208 9.271e-212 691.0
HFD2_k127_144743_2 CBS domain K04767 - - 0.0000000000000001366 85.0
HFD2_k127_144743_3 BNR repeat-like domain - - - 0.00000000000005375 86.0
HFD2_k127_144743_4 Cytidylate kinase-like family K00945 - 2.7.4.25 0.000000007617 62.0
HFD2_k127_144743_5 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog K03088 - - 0.000026 53.0
HFD2_k127_1467026_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 505.0
HFD2_k127_1467026_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000005739 222.0
HFD2_k127_1471352_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 313.0
HFD2_k127_1471352_1 SCO1/SenC K07152,K08976 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003552 274.0
HFD2_k127_1471352_2 Cytochrome c oxidase, subunit III K02276,K02299 - 1.9.3.1 0.000000000000000000000000000000000000000000000000004116 188.0
HFD2_k127_1471352_3 Prokaryotic Cytochrome C oxidase subunit IV - - - 0.0000946 50.0
HFD2_k127_1479646_0 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 594.0
HFD2_k127_1479646_1 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 398.0
HFD2_k127_1479646_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000008785 228.0
HFD2_k127_1479646_3 Tetratricopeptide repeat - - - 0.0000000000000116 86.0
HFD2_k127_1493988_1 FMN binding K03612 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000001941 66.0
HFD2_k127_1493988_2 Tetratricopeptide repeat - - - 0.0000006717 61.0
HFD2_k127_1495064_0 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 1.965e-220 704.0
HFD2_k127_1495064_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 604.0
HFD2_k127_1495064_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000006025 240.0
HFD2_k127_1495064_3 Proteasome subunit K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000002551 234.0
HFD2_k127_1495064_4 Fibronectin type III domain protein - - - 0.000000000000000000000000000000001133 145.0
HFD2_k127_1495064_5 Histidine kinase K10914 - - 0.00000000000000000000000001176 114.0
HFD2_k127_1495064_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000004444 65.0
HFD2_k127_1495064_7 Putative transmembrane protein (PGPGW) - - - 0.000002322 53.0
HFD2_k127_1507449_0 guanyl-nucleotide exchange factor activity - - - 0.0000000000000000000000000000000002001 147.0
HFD2_k127_1507449_1 Peptidase family C25 - - - 0.000000000000000000000000000000001293 152.0
HFD2_k127_1507449_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000003387 106.0
HFD2_k127_152318_0 Domain of unknown function (DUF1998) K02336,K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 426.0
HFD2_k127_152318_1 Cyclophilin-like K09143 - - 0.000000000000000000000000000000002754 133.0
HFD2_k127_1533142_0 tRNA processing K06864,K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000001513 254.0
HFD2_k127_1533142_1 BioY family K03523 - - 0.0000000000000000000000005824 113.0
HFD2_k127_1539551_0 Beta-eliminating lyase K01667 - 4.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 563.0
HFD2_k127_1539551_1 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 320.0
HFD2_k127_1539551_2 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.00000000000000000000000006704 110.0
HFD2_k127_1547780_0 Sporulation initiation inhibitor protein Soj K03496 - - 0.000000000000000000000000000000000000000000000000000000003138 208.0
HFD2_k127_1547780_1 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000898 211.0
HFD2_k127_1547780_2 bacterial-type flagellum organization K02282,K04562 - - 0.00000000000000000000000000000000000000000000001598 189.0
HFD2_k127_1550453_0 smart pdz dhr glgf K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 385.0
HFD2_k127_1550453_1 TPR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008097 264.0
HFD2_k127_1566711_0 FAD dependent oxidoreductase K00301 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 342.0
HFD2_k127_1566711_1 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000001027 167.0
HFD2_k127_1566711_2 Fatty acid desaturase K00507 - 1.14.19.1 0.0008668 42.0
HFD2_k127_1569252_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 361.0
HFD2_k127_1569252_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000001151 254.0
HFD2_k127_1569252_2 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000005361 167.0
HFD2_k127_1569252_3 EXOIII K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000124 164.0
HFD2_k127_1569252_4 5'-nucleotidase - - - 0.00000000000000000000000000000000000001245 160.0
HFD2_k127_1569252_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000001692 138.0
HFD2_k127_1569252_8 Cell wall-active antibiotics response 4TMS YvqF K11622 - - 0.00002609 49.0
HFD2_k127_1586093_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 473.0
HFD2_k127_1599059_0 Spermine/spermidine synthase domain - - - 0.00000000000000000000000000000000000000000003198 180.0
HFD2_k127_1599059_1 O-linked N-acetylglucosamine transferase, SPINDLY family - - - 0.0000000001753 74.0
HFD2_k127_1619403_0 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 527.0
HFD2_k127_1619403_1 Belongs to the carbamoyltransferase HypF family K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 426.0
HFD2_k127_1619403_2 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000003913 240.0
HFD2_k127_1619403_3 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.000000000000000000000573 101.0
HFD2_k127_1630649_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 361.0
HFD2_k127_1630649_1 COGs COG1740 Ni Fe-hydrogenase I small subunit K06282 - 1.12.99.6 0.000000000000000000000000000000000000003053 151.0
HFD2_k127_1639855_0 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 383.0
HFD2_k127_1639855_1 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000001581 146.0
HFD2_k127_1639855_2 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000766 100.0
HFD2_k127_1639855_3 PFAM Fimbrial assembly family protein K02663 - - 0.000000000101 70.0
HFD2_k127_1639855_5 Di-haem oxidoreductase, putative peroxidase K01201 - 3.2.1.45 0.00000009815 62.0
HFD2_k127_1639855_6 chaperone-mediated protein folding K20543 - - 0.000005661 52.0
HFD2_k127_1682729_0 Aminotransferase class-V K04127 - 5.1.1.17 0.000000000000000000000000000000000000000000000000000000004871 212.0
HFD2_k127_1682729_1 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000002799 115.0
HFD2_k127_1684153_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 557.0
HFD2_k127_1684153_1 - - - - 0.0000002018 53.0
HFD2_k127_1696082_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.262e-297 934.0
HFD2_k127_169626_0 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 375.0
HFD2_k127_169626_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000002805 160.0
HFD2_k127_1699965_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.224e-233 730.0
HFD2_k127_170036_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000482 412.0
HFD2_k127_170036_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007705 315.0
HFD2_k127_170036_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000004102 220.0
HFD2_k127_170036_3 PFAM von Willebrand factor type A - - - 0.00000000000000000000000000000000000000000000004676 185.0
HFD2_k127_170036_4 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000001624 126.0
HFD2_k127_170036_5 TPR repeat - - - 0.00000000000000000000006228 113.0
HFD2_k127_170036_6 Carboxypeptidase regulatory-like domain - - - 0.00000001873 64.0
HFD2_k127_170036_7 PFAM YbbR family protein - - - 0.00004421 55.0
HFD2_k127_170036_8 - - - - 0.0009014 46.0
HFD2_k127_1705988_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 426.0
HFD2_k127_1705988_1 3-demethylubiquinone-9 3-O-methyltransferase activity K16328 - 2.7.1.83 0.0000000000000000000000000000006979 124.0
HFD2_k127_1705988_2 COG1045 Serine acetyltransferase K00640 - 2.3.1.30 0.0000000000000009189 80.0
HFD2_k127_1730621_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 470.0
HFD2_k127_1730621_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 359.0
HFD2_k127_1730621_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000135 143.0
HFD2_k127_1730621_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000003875 126.0
HFD2_k127_1731087_0 Receptor K02014,K16087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007736 394.0
HFD2_k127_1731087_1 SMART Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 351.0
HFD2_k127_1744247_0 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 389.0
HFD2_k127_1744247_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000873 381.0
HFD2_k127_1799373_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 402.0
HFD2_k127_1799373_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001166 248.0
HFD2_k127_1799373_2 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.000000000000000000000000000000000000000000000000000001611 198.0
HFD2_k127_1799373_3 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000306 106.0
HFD2_k127_1799373_4 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000001651 85.0
HFD2_k127_1799373_5 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000001651 82.0
HFD2_k127_180401_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 2.257e-268 835.0
HFD2_k127_180401_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 441.0
HFD2_k127_180401_2 Predicted integral membrane protein (DUF2270) - - - 0.000000000000000000000000000000000000000000000006292 181.0
HFD2_k127_180401_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000005855 98.0
HFD2_k127_1807865_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009306 573.0
HFD2_k127_1807865_1 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007345 286.0
HFD2_k127_1810827_0 Belongs to the GSP D family - - - 0.0000000000000000000000000000000000000009528 169.0
HFD2_k127_1810827_1 Domain of unknown function DUF11 - - - 0.000000000000000000001272 111.0
HFD2_k127_1810827_2 TIGRFAM conserved repeat domain - - - 0.00000000000000000001586 98.0
HFD2_k127_1810827_3 Putative Flp pilus-assembly TadE/G-like - - - 0.0000004545 63.0
HFD2_k127_1812499_0 response regulator K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 413.0
HFD2_k127_1812499_1 GAF domain - - - 0.0000000000000000000000000000000000000000000000328 184.0
HFD2_k127_1812499_2 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000003025 149.0
HFD2_k127_1812499_3 response regulator K10943 - - 0.0000000000000000000000008199 108.0
HFD2_k127_1817441_0 Cytochrome C assembly protein K02198,K04016 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - 9.337e-194 629.0
HFD2_k127_1817441_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008565 508.0
HFD2_k127_1817441_10 subunit of a heme lyase K02200 - - 0.00000000000000003541 87.0
HFD2_k127_1817441_11 Response regulator, receiver - - - 0.0000000006595 71.0
HFD2_k127_1817441_12 the current gene model (or a revised gene model) may contain a frame shift - - - 0.0000000008919 62.0
HFD2_k127_1817441_13 - - - - 0.00000005502 60.0
HFD2_k127_1817441_14 E-Z type HEAT repeats - - - 0.00001215 58.0
HFD2_k127_1817441_2 PFAM Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000006103 235.0
HFD2_k127_1817441_3 PFAM ABC transporter K01990,K02193,K09697 - 3.6.3.41,3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000806 217.0
HFD2_k127_1817441_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000002185 214.0
HFD2_k127_1817441_5 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000004026 206.0
HFD2_k127_1817441_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000114 171.0
HFD2_k127_1817441_7 COG2386 ABC-type transport system involved in cytochrome c biogenesis, permease component K02194 - - 0.00000000000000000000000000000000000002061 155.0
HFD2_k127_1817441_8 cytokinin biosynthetic process K06966 - 3.2.2.10 0.00000000000000000000000001988 121.0
HFD2_k127_1817441_9 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000001591 89.0
HFD2_k127_1818982_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 421.0
HFD2_k127_1818982_1 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000004214 149.0
HFD2_k127_1828332_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 445.0
HFD2_k127_1828332_1 PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000761 390.0
HFD2_k127_1828332_2 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009655 296.0
HFD2_k127_1828332_3 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.0000000000000000000000000000000000000000000000000000000000000000001347 239.0
HFD2_k127_1828332_4 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000002589 64.0
HFD2_k127_1828332_5 His Kinase A (phosphoacceptor) domain K07679 - 2.7.13.3 0.00000218 58.0
HFD2_k127_1833090_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 290.0
HFD2_k127_1833090_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000001162 224.0
HFD2_k127_1833090_2 Peptidase M56 - - - 0.00000000000000000000000000001524 135.0
HFD2_k127_183344_0 Zinc carboxypeptidase K14054 - - 3.541e-290 917.0
HFD2_k127_1871852_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 320.0
HFD2_k127_1871852_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 298.0
HFD2_k127_1871852_2 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000001003 229.0
HFD2_k127_1871852_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000203 165.0
HFD2_k127_1871852_4 Sporulation and spore germination - - - 0.00000000000000000000000006929 119.0
HFD2_k127_1893162_0 Belongs to the PstS family K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004066 411.0
HFD2_k127_1893162_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007655 317.0
HFD2_k127_1893162_2 Phosphate transport system permease protein PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 288.0
HFD2_k127_1893162_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000002073 153.0
HFD2_k127_1893162_4 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000004304 100.0
HFD2_k127_1898976_0 Belongs to the pseudouridine synthase RluA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 400.0
HFD2_k127_1898976_1 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 0.0000000000000000000000000000000000000003463 163.0
HFD2_k127_1932846_0 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 317.0
HFD2_k127_1932846_1 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000007309 250.0
HFD2_k127_1932846_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000003155 163.0
HFD2_k127_1968606_0 NAD+ binding K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 326.0
HFD2_k127_1968606_1 Amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000001031 191.0
HFD2_k127_1968606_2 Acetyltransferase (GNAT) family - - - 0.00000000000000000000005389 100.0
HFD2_k127_1970669_0 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 419.0
HFD2_k127_1970669_1 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 340.0
HFD2_k127_1970669_2 PFAM thioesterase superfamily protein - - - 0.000000000000000000007215 96.0
HFD2_k127_1975877_0 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 372.0
HFD2_k127_1975877_1 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000003317 185.0
HFD2_k127_1975877_2 HlyD family secretion protein - - - 0.00000000000000000000000000009984 123.0
HFD2_k127_1975877_3 CAAX amino terminal protease family K07052 - - 0.00000000000000000004873 102.0
HFD2_k127_1975877_4 ggdef domain - - - 0.000000000004276 71.0
HFD2_k127_1975877_5 Carboxypeptidase regulatory-like domain - - - 0.0002106 53.0
HFD2_k127_1975877_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0007318 42.0
HFD2_k127_1983280_0 Thiamine biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005367 336.0
HFD2_k127_1983280_1 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000001054 90.0
HFD2_k127_1997572_0 Glycosyl transferase WecB/TagA/CpsF family - - - 0.000000000000000000000000000000000000000000000000000000003817 208.0
HFD2_k127_1997572_1 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000001577 154.0
HFD2_k127_1999095_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 311.0
HFD2_k127_1999095_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000004841 87.0
HFD2_k127_1999095_2 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000423 53.0
HFD2_k127_2002335_0 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 341.0
HFD2_k127_2002335_1 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.00000000000000000000000000000002401 131.0
HFD2_k127_2002335_2 PFAM Class I peptide chain release factor K15034 - - 0.000000000000000000000000000001239 127.0
HFD2_k127_2007716_0 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 7.283e-236 738.0
HFD2_k127_2007716_1 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000001907 143.0
HFD2_k127_2011879_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 443.0
HFD2_k127_2011879_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000001791 228.0
HFD2_k127_2011879_2 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000003689 121.0
HFD2_k127_2011879_3 peptidyl-tyrosine sulfation - - - 0.00000000000000001916 91.0
HFD2_k127_2041172_0 aminopeptidase K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 597.0
HFD2_k127_2041172_1 Pyridoxal-dependent decarboxylase conserved domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 439.0
HFD2_k127_2041172_2 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.000000000000000000000000000000000001954 143.0
HFD2_k127_2046384_0 Seven times multi-haem cytochrome CxxCH - - - 0.0000000000000000000000000000000000000000000000000000000000001858 229.0
HFD2_k127_2046384_1 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000001597 189.0
HFD2_k127_2046384_2 Tetratricopeptide repeat - - - 0.0000000000000005772 92.0
HFD2_k127_2062518_0 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 429.0
HFD2_k127_2062518_1 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000005876 200.0
HFD2_k127_206330_0 Diguanylate cyclase, GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000003065 205.0
HFD2_k127_206330_1 TIGRFAM phosphodiesterase, MJ0936 - - - 0.00000000000000000000000000000000000000005267 161.0
HFD2_k127_206330_2 Belongs to the GSP D family K02453 - - 0.000000002159 66.0
HFD2_k127_206330_3 Thrombospondin type 3 repeat K04659 - - 0.000000567 61.0
HFD2_k127_2068456_0 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 463.0
HFD2_k127_2068456_1 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.00000000000000000000000000000000000000006105 155.0
HFD2_k127_2084239_0 Permease YjgP YjgQ family protein K07091,K11720 - - 0.00000000000000000000146 96.0
HFD2_k127_2084239_1 Tetratricopeptide repeat - - - 0.00000001937 59.0
HFD2_k127_2091059_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001978 284.0
HFD2_k127_2091059_1 TIGRFAM TonB family protein K03832 - - 0.0000000000001942 80.0
HFD2_k127_2100604_0 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009127 354.0
HFD2_k127_2100604_1 S-(hydroxymethyl)glutathione dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 341.0
HFD2_k127_2100604_2 benzoyl-CoA reductase K04113 - 1.3.7.8 0.000000000000000000000000000009457 135.0
HFD2_k127_2140971_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 1.41e-234 740.0
HFD2_k127_2140971_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000001547 151.0
HFD2_k127_2140971_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000006863 127.0
HFD2_k127_2141428_0 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 350.0
HFD2_k127_2141428_1 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000007942 222.0
HFD2_k127_2141428_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000002779 171.0
HFD2_k127_2141428_3 PFAM lipid A biosynthesis domain protein - - - 0.000000000000000000000001124 107.0
HFD2_k127_2141428_4 - - - - 0.000000000008137 74.0
HFD2_k127_2141428_5 Zinc-dependent metalloprotease - - - 0.00000001098 68.0
HFD2_k127_2141428_6 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000001995 58.0
HFD2_k127_2143341_0 elongation factor G K02355 - - 1.379e-278 874.0
HFD2_k127_215027_0 Domain of Unknown Function (DUF1259) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002025 286.0
HFD2_k127_215027_1 epoxide hydrolase - - - 0.00000000000000000000000000000000000000000005461 162.0
HFD2_k127_215027_2 BrnA antitoxin of type II toxin-antitoxin system - - - 0.00000000000000000005493 93.0
HFD2_k127_2156168_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000007882 133.0
HFD2_k127_2156168_1 chitinase K01183 - 3.2.1.14 0.000002276 61.0
HFD2_k127_2161235_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 357.0
HFD2_k127_2161235_1 Histidine kinase - - - 0.00000000000001401 76.0
HFD2_k127_2167341_0 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001973 280.0
HFD2_k127_2167341_1 SMC proteins Flexible Hinge Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007496 245.0
HFD2_k127_2167341_2 Protein of unknown function (DUF520) K09767 GO:0000049,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000002479 187.0
HFD2_k127_2167341_3 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000004248 100.0
HFD2_k127_2167341_4 Tetratricopeptide repeat - - - 0.0006266 52.0
HFD2_k127_2183313_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006697 573.0
HFD2_k127_2183313_1 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 509.0
HFD2_k127_2183313_2 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 507.0
HFD2_k127_2183313_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 384.0
HFD2_k127_2183313_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000003914 184.0
HFD2_k127_2187417_0 Glycosyl transferase WecB/TagA/CpsF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001528 275.0
HFD2_k127_2187417_1 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000003228 154.0
HFD2_k127_2187417_2 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000001031 85.0
HFD2_k127_2190585_0 ATPase (AAA superfamily K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 422.0
HFD2_k127_2190585_1 Domain of unknown function(DUF2779) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 387.0
HFD2_k127_2190585_2 cellular response to heat K09807 - - 0.00000000000000000000000000000000000004208 153.0
HFD2_k127_2190585_3 Amidohydrolase family - - - 0.00000000009301 63.0
HFD2_k127_2190585_4 - - - - 0.00000006961 61.0
HFD2_k127_2207105_0 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.00000000000000000000000000000000000000000000000000000000000000000009389 246.0
HFD2_k127_2207105_1 Cytochrome c K02720 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.000000000000000000000002265 110.0
HFD2_k127_2207105_2 PAS fold - - - 0.00008661 46.0
HFD2_k127_2208265_0 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 441.0
HFD2_k127_2208265_1 Thioesterase superfamily - - - 0.00000000000000000000000000000000000001169 150.0
HFD2_k127_2208265_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000001402 125.0
HFD2_k127_2215349_0 long-chain fatty acid transport protein - - - 0.00000000000000000000000004097 124.0
HFD2_k127_2215349_1 oxidoreductase activity - - - 0.00000000000007455 86.0
HFD2_k127_2227731_0 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 613.0
HFD2_k127_2227731_1 Short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000007896 215.0
HFD2_k127_2227731_2 SurA N-terminal domain K03769 - 5.2.1.8 0.0008386 48.0
HFD2_k127_2236887_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003935 264.0
HFD2_k127_2236887_1 O-linked N-acetylglucosamine transferase, SPINDLY family - - - 0.0000000000000000000000000000000002679 146.0
HFD2_k127_2236887_2 nuclear chromosome segregation - - - 0.00000000000000003814 93.0
HFD2_k127_2245862_0 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009434 301.0
HFD2_k127_2245862_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000003505 201.0
HFD2_k127_227125_0 Carbamoyl-phosphate synthetase large chain domain protein K01955 - 6.3.5.5 0.0 1064.0
HFD2_k127_227125_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000000168 184.0
HFD2_k127_2273913_0 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000145 274.0
HFD2_k127_2273913_1 long-chain fatty acid transporting porin activity K06076 - - 0.00000000000000000000000000000000000000000000001058 188.0
HFD2_k127_2273913_2 cellulase activity K00226,K05349 - 1.3.98.1,3.2.1.21 0.00000000000002612 88.0
HFD2_k127_2296295_0 FecR protein - - - 0.00000000000000000000000000000000000000000009838 179.0
HFD2_k127_2301031_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009883 469.0
HFD2_k127_2301031_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008464 450.0
HFD2_k127_2301031_10 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000002716 66.0
HFD2_k127_2301031_2 Carbamoyl-phosphate synthetase large chain domain protein K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 346.0
HFD2_k127_2301031_3 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007389 310.0
HFD2_k127_2301031_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001925 256.0
HFD2_k127_2301031_5 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000001427 244.0
HFD2_k127_2301031_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000002935 188.0
HFD2_k127_2301031_7 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000148 183.0
HFD2_k127_2301031_8 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000188 143.0
HFD2_k127_2301031_9 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000006154 129.0
HFD2_k127_2302821_0 helicase superfamily c-terminal domain K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 341.0
HFD2_k127_2302821_1 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000005198 198.0
HFD2_k127_2302821_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000017 116.0
HFD2_k127_2349001_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000227 250.0
HFD2_k127_2349001_1 PFAM ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000001178 219.0
HFD2_k127_2349001_2 TonB dependent receptor K16092 - - 0.0000000000000000001338 101.0
HFD2_k127_2350922_0 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 430.0
HFD2_k127_2350922_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 355.0
HFD2_k127_2350922_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001113 279.0
HFD2_k127_2350922_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000006027 260.0
HFD2_k127_2350922_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000001099 145.0
HFD2_k127_2350922_5 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000005266 117.0
HFD2_k127_2350922_6 PFAM Lytic transglycosylase catalytic K08309 - - 0.0000000000000000000003249 104.0
HFD2_k127_2350922_7 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000001189 95.0
HFD2_k127_2350922_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000008592 59.0
HFD2_k127_237681_0 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 355.0
HFD2_k127_237681_1 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000005292 252.0
HFD2_k127_237681_2 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000001041 141.0
HFD2_k127_2377733_0 Tetratricopeptide repeat - - - 0.000000575 63.0
HFD2_k127_2392386_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00122,K00335 - 1.17.1.9,1.6.5.3 1.174e-196 633.0
HFD2_k127_2392386_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 497.0
HFD2_k127_2396638_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000275 210.0
HFD2_k127_2396638_1 integral membrane protein - - - 0.000000000000000000000000000000000001337 148.0
HFD2_k127_2396638_2 Diguanylate cyclase - - - 0.00002639 50.0
HFD2_k127_2396638_3 Protein of unknown function (DUF2752) - - - 0.0001414 53.0
HFD2_k127_2428607_0 Pyridine nucleotide-disulphide oxidoreductase - - - 1.649e-208 662.0
HFD2_k127_2465132_0 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K12452,K13328 - 1.17.1.1,4.2.1.164 1.314e-195 633.0
HFD2_k127_2465132_1 PFAM NAD-dependent epimerase dehydratase K01709 - 4.2.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 429.0
HFD2_k127_2465132_2 TIGRFAM glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 376.0
HFD2_k127_2465132_3 dTDP-4-dehydrorhamnose reductase K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000001881 257.0
HFD2_k127_2465132_4 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000003015 222.0
HFD2_k127_2465132_5 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000005383 120.0
HFD2_k127_2465299_0 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002372 254.0
HFD2_k127_2465299_1 membrane - GO:0005575,GO:0016020 - 0.000000000000000000000009078 116.0
HFD2_k127_2465299_2 UbiA prenyltransferase family K12501 - 2.5.1.117 0.0000000000000000002075 102.0
HFD2_k127_2465299_3 Phosphoserine phosphatase - - - 0.00000000000001365 87.0
HFD2_k127_2465299_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000005231 78.0
HFD2_k127_2465299_5 Male sterility protein K15891 - 1.1.1.354 0.00000006674 57.0
HFD2_k127_2467287_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000002487 229.0
HFD2_k127_2467287_1 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.0000000000000000000000000000000000000000005637 173.0
HFD2_k127_2469358_0 Fumarate reductase flavoprotein C-term K00239,K00244 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 573.0
HFD2_k127_2469358_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000007826 213.0
HFD2_k127_2502393_0 Surface antigen K07277,K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000004328 256.0
HFD2_k127_2502393_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000002265 100.0
HFD2_k127_2502393_2 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.000000000000000229 88.0
HFD2_k127_2502393_3 antisigma factor binding K03598 - - 0.0004101 50.0
HFD2_k127_2511697_0 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009613 451.0
HFD2_k127_2511697_1 PFAM Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000138 286.0
HFD2_k127_2511697_2 TIGRFAM carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.0000000002327 69.0
HFD2_k127_2511805_0 PQQ-like domain K05889 - 1.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 399.0
HFD2_k127_2511805_1 PFAM Proprotein convertase P-domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000901 263.0
HFD2_k127_2511805_2 Predicted membrane protein (DUF2127) - - - 0.0000000000001082 78.0
HFD2_k127_2513876_0 Short chain fatty acid transporter K02106 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005824 524.0
HFD2_k127_2513876_1 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 507.0
HFD2_k127_2513876_2 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 474.0
HFD2_k127_2513876_3 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 389.0
HFD2_k127_2513876_4 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001068 270.0
HFD2_k127_2513876_5 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000004406 187.0
HFD2_k127_2513876_6 YceI-like domain - - - 0.000000000000000000000000000000000000000000000006292 181.0
HFD2_k127_2513876_7 COG0694 Thioredoxin-like proteins and domains - - - 0.00000000000000000000000000008307 117.0
HFD2_k127_2516953_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000006049 219.0
HFD2_k127_2547035_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000009276 188.0
HFD2_k127_2547035_1 Bacterial virulence protein (VirJ) - - - 0.000000000000009994 87.0
HFD2_k127_2547035_2 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms K01992,K07027,K14205 - 2.3.2.3 0.00000003062 66.0
HFD2_k127_2564844_0 long-chain fatty acid transporting porin activity K06076 - - 0.0000000000000000000002179 112.0
HFD2_k127_2566564_0 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009328 291.0
HFD2_k127_2566564_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000001592 260.0
HFD2_k127_2566612_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 8.99e-206 655.0
HFD2_k127_2566612_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 318.0
HFD2_k127_2571817_0 glutamate dehydrogenase [NAD(P)+] activity K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 7.27e-215 674.0
HFD2_k127_2571817_1 fumarate reductase, flavoprotein subunit K00239,K00244 - 1.3.5.1,1.3.5.4 5.725e-202 645.0
HFD2_k127_2573575_0 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006086 374.0
HFD2_k127_2573575_1 Transporter, CPA2 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 372.0
HFD2_k127_2585012_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000004146 117.0
HFD2_k127_2586843_0 Tricorn protease homolog K08676 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 463.0
HFD2_k127_2590673_0 Domain of unknown function (DUF4388) - - - 0.00000000000000000103 100.0
HFD2_k127_2590673_1 Phosphate-selective porin O and P - - - 0.0000000000003249 81.0
HFD2_k127_2590673_2 Cytochrome c554 and c-prime - - - 0.0002299 47.0
HFD2_k127_2590777_0 Glutamine amidotransferase domain K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 523.0
HFD2_k127_2590777_1 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000007664 232.0
HFD2_k127_262343_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000006265 115.0
HFD2_k127_262343_1 - - - - 0.000002706 58.0
HFD2_k127_2630041_0 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001773 287.0
HFD2_k127_263172_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 352.0
HFD2_k127_263172_1 Elongation factor SelB, winged helix K03833 - - 0.0000000000000000000004913 100.0
HFD2_k127_263172_2 protein secretion K03116 - - 0.00001639 54.0
HFD2_k127_2639365_0 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 436.0
HFD2_k127_2639365_1 Bacterial regulatory protein, Fis family K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 436.0
HFD2_k127_2639365_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007107 257.0
HFD2_k127_2639365_3 involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000005487 235.0
HFD2_k127_2639365_4 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000009667 228.0
HFD2_k127_272405_0 Belongs to the ClpA ClpB family K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 604.0
HFD2_k127_272405_1 Surface antigen K07277 - - 0.000000000000000000000000000000823 138.0
HFD2_k127_2728603_0 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000006424 216.0
HFD2_k127_2728603_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000009977 163.0
HFD2_k127_2728603_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000006154 89.0
HFD2_k127_2728603_3 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000612 87.0
HFD2_k127_2728603_4 - - - - 0.0000001339 60.0
HFD2_k127_2728603_5 Putative adhesin - - - 0.000003 59.0
HFD2_k127_2739933_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016151,GO:0016491,GO:0022900,GO:0030288,GO:0030313,GO:0031975,GO:0032991,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0044569,GO:0045333,GO:0046872,GO:0046914,GO:0055114,GO:0071944,GO:1902494 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 419.0
HFD2_k127_2739933_1 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.000000000000000000000000000000000000000001208 162.0
HFD2_k127_2739933_2 COGs COG1969 Ni Fe-hydrogenase I cytochrome b subunit K03620 - - 0.000000000000000000000000000009378 120.0
HFD2_k127_2739933_3 - - - - 0.0000000000000006957 84.0
HFD2_k127_2752931_0 aconitate hydratase K01681 - 4.2.1.3 2.889e-294 924.0
HFD2_k127_2753209_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 458.0
HFD2_k127_2753209_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000308 278.0
HFD2_k127_2753209_2 Domain of unknown function (DUF2437) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001473 274.0
HFD2_k127_2753209_3 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001087 250.0
HFD2_k127_2753209_4 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774,K22110 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659 - 0.000000000000000000000000000000000000000000000000000000000001577 238.0
HFD2_k127_2753209_5 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.000000000000000000000000000000000000000000000000000001257 212.0
HFD2_k127_2753209_6 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000003735 134.0
HFD2_k127_2753209_7 Domain of unknown function (DUF1731) K07071 - - 0.00004682 47.0
HFD2_k127_2771444_0 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 384.0
HFD2_k127_2771444_1 cyclic nucleotide binding K07058,K14266 - 1.14.19.9 0.00000000000000000000000001744 114.0
HFD2_k127_2771444_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000001814 108.0
HFD2_k127_2771444_3 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.0000000000000000007206 89.0
HFD2_k127_2772739_0 PFAM Type II secretion system F domain K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 461.0
HFD2_k127_2772739_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 401.0
HFD2_k127_2772739_2 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 334.0
HFD2_k127_2772739_3 Two component, sigma54 specific, transcriptional regulator, Fis family K07713,K07714,K19641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001087 250.0
HFD2_k127_2778237_0 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000001738 244.0
HFD2_k127_2778237_1 RelA SpoT domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001237 235.0
HFD2_k127_2779168_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 394.0
HFD2_k127_2779168_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004559 241.0
HFD2_k127_2779168_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K06187,K09747 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.0000000000000000000000059 104.0
HFD2_k127_2801847_0 Proton-conducting membrane transporter K12137,K15828 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 585.0
HFD2_k127_2801847_1 NADH dehydrogenase K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 334.0
HFD2_k127_2801847_2 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000009469 113.0
HFD2_k127_2816053_0 belongs to the thioredoxin family K03671,K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 590.0
HFD2_k127_2816053_1 lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006817 379.0
HFD2_k127_2816053_2 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000001091 197.0
HFD2_k127_2823528_0 PFAM PfkB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 360.0
HFD2_k127_2823528_1 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000009026 137.0
HFD2_k127_2823528_2 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000001381 132.0
HFD2_k127_2823528_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.000000008819 65.0
HFD2_k127_2823528_5 Domain of unknown function (DUF4388) - - - 0.000002817 60.0
HFD2_k127_2823528_6 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00001569 47.0
HFD2_k127_2837352_0 Catalyzes the conversion of dihydroorotate to orotate K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 369.0
HFD2_k127_2837352_1 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006303 291.0
HFD2_k127_2837352_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000009725 224.0
HFD2_k127_2837352_3 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000004951 233.0
HFD2_k127_2837352_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000397 138.0
HFD2_k127_2837352_5 cell redox homeostasis - - - 0.00000000000004072 78.0
HFD2_k127_284684_0 phosphorelay signal transduction system K02437 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 473.0
HFD2_k127_284684_1 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000003074 180.0
HFD2_k127_284684_2 response regulator - - - 0.00000000000000001999 93.0
HFD2_k127_2872639_0 biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000002953 201.0
HFD2_k127_2872639_1 Glutamine amidotransferase domain K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000006119 187.0
HFD2_k127_2872639_2 Nodulation protein S (NodS) - - - 0.000003278 60.0
HFD2_k127_288401_0 Histidine kinase - - - 0.0000000000000000000000000004161 127.0
HFD2_k127_288401_1 Histidine kinase - - - 0.0000003567 59.0
HFD2_k127_2906772_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000004601 253.0
HFD2_k127_2906772_1 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000007135 108.0
HFD2_k127_2906772_2 PFAM Single-stranded nucleic acid binding R3H K06346 - - 0.000000000000000001006 93.0
HFD2_k127_2906772_3 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000001512 91.0
HFD2_k127_2906772_4 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000004351 64.0
HFD2_k127_2906772_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000001394 62.0
HFD2_k127_2909511_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 413.0
HFD2_k127_2909511_1 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 395.0
HFD2_k127_2909511_10 Uncharacterized ACR, COG1399 K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000006274 96.0
HFD2_k127_2909511_11 heat shock protein binding K05516,K05801 - - 0.0000000000396 76.0
HFD2_k127_2909511_12 chaperone-mediated protein folding - - - 0.000000001219 71.0
HFD2_k127_2909511_2 Belongs to the RimK family K05844,K14940 - 6.3.2.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 344.0
HFD2_k127_2909511_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005255 322.0
HFD2_k127_2909511_4 succinate dehydrogenase subunit K06987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 301.0
HFD2_k127_2909511_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001879 273.0
HFD2_k127_2909511_6 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001277 261.0
HFD2_k127_2909511_7 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000001089 142.0
HFD2_k127_2909511_8 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000001051 101.0
HFD2_k127_2909511_9 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 1 K07025 - - 0.00000000000000000000007116 110.0
HFD2_k127_2924058_0 Squalene/phytoene synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008527 271.0
HFD2_k127_2924058_1 Phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000004345 266.0
HFD2_k127_293820_0 PFAM Type II secretion system F domain K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001059 267.0
HFD2_k127_293820_1 Type II and III secretion system protein K02666 - - 0.0007624 50.0
HFD2_k127_2940911_0 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004972 580.0
HFD2_k127_2940911_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000006961 97.0
HFD2_k127_297604_0 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.0000000000000000000000000000000002154 142.0
HFD2_k127_297604_1 Transcriptional regulator - - - 0.00000000000000000000000000000007329 129.0
HFD2_k127_297604_2 SurA N-terminal domain K03769 - 5.2.1.8 0.000000000000000000000000000001307 124.0
HFD2_k127_297604_3 COG2146 Ferredoxin subunits of nitrite reductase and K00363,K05710 - 1.7.1.15 0.000000000000000000003485 97.0
HFD2_k127_297604_4 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000006238 94.0
HFD2_k127_2977900_0 Cytochrome c554 and c-prime - - - 3.176e-279 878.0
HFD2_k127_2977900_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0030312,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046429,GO:0046490,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 424.0
HFD2_k127_2977900_2 PFAM Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000006974 136.0
HFD2_k127_2994936_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000003562 240.0
HFD2_k127_2994936_1 - - - - 0.000000000000000000000000000000000008543 149.0
HFD2_k127_2994936_2 arylsulfatase activity - - - 0.0000000000000000000000000000000126 138.0
HFD2_k127_299587_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 420.0
HFD2_k127_299587_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 334.0
HFD2_k127_3012598_0 Belongs to the peptidase M24B family K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000002366 223.0
HFD2_k127_3012598_1 Cytochrome c554 and c-prime K01119 - 3.1.3.6,3.1.4.16 0.00000000000000000000002263 114.0
HFD2_k127_3012938_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 430.0
HFD2_k127_3012938_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 337.0
HFD2_k127_3012938_2 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002168 283.0
HFD2_k127_3012938_3 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.0000000000000000000000000000000000000000000000000007228 192.0
HFD2_k127_3012938_4 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000002028 160.0
HFD2_k127_3012938_5 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000004993 122.0
HFD2_k127_3022708_0 Lanthionine synthetase C-like protein - - - 1.037e-220 708.0
HFD2_k127_3022708_1 Peptidase C39 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 375.0
HFD2_k127_3034229_0 - - - - 0.00000000000000000000000000000000000000000000000004437 190.0
HFD2_k127_3034229_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.000000000000000000000000000000000000000001696 163.0
HFD2_k127_3034229_2 Biogenesis protein K09792 - - 0.0000000000000000000008516 103.0
HFD2_k127_3037187_1 YacP-like NYN domain K06962 - - 0.00000000003305 73.0
HFD2_k127_3046310_0 PFAM Alpha beta hydrolase K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 362.0
HFD2_k127_3046310_1 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001151 272.0
HFD2_k127_3046310_2 serine-type peptidase activity K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000289 238.0
HFD2_k127_3046310_3 - - - - 0.000000000000000000000000000001009 126.0
HFD2_k127_3046310_4 PFAM nucleic acid binding, OB-fold, tRNA K01174 - 3.1.31.1 0.0000000000000000000001056 111.0
HFD2_k127_3052368_0 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000002501 196.0
HFD2_k127_3052368_1 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 0.00000000000000000000000000000000000000000000000003471 181.0
HFD2_k127_3060424_0 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 387.0
HFD2_k127_3060424_2 Peptidase M3A and M3B thimet oligopeptidase F - - - 0.0002483 50.0
HFD2_k127_3063886_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 529.0
HFD2_k127_3063886_1 Cache domain - - - 0.000000000000000000000000000000000000000000000001922 181.0
HFD2_k127_3063886_2 NlpC/P60 family K01227,K01447,K01448,K01876,K06385,K07260,K11060,K11062,K21471,K21472 - 3.2.1.96,3.4.17.14,3.5.1.28,6.1.1.12 0.0002792 51.0
HFD2_k127_3068940_0 Cell wall formation - - - 0.000000000000000000000000000000000001679 144.0
HFD2_k127_3068940_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000009558 96.0
HFD2_k127_3068940_2 Essential cell division protein K03589 - - 0.000000001227 70.0
HFD2_k127_3095189_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000004285 224.0
HFD2_k127_3095189_1 oxidation-reduction process - - - 0.0000000000000000000000000000000005138 146.0
HFD2_k127_3126770_0 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 303.0
HFD2_k127_3126770_1 Sodium:sulfate symporter transmembrane region K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000002104 244.0
HFD2_k127_3126770_2 Dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000003136 216.0
HFD2_k127_3126770_3 Dual specificity phosphatase, catalytic domain - - - 0.00000000000000000000000000000000000001133 149.0
HFD2_k127_3126770_4 - - - - 0.0000000000000000000000001919 111.0
HFD2_k127_3133974_1 Pilus formation protein N terminal region K02280 - - 0.00000000000002307 87.0
HFD2_k127_3145748_0 amine dehydrogenase activity - - - 0.000000004764 67.0
HFD2_k127_3147886_0 Choline monooxygenase K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 318.0
HFD2_k127_3147886_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003104 280.0
HFD2_k127_3147886_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000164 215.0
HFD2_k127_3147886_3 alpha-galactosidase - - - 0.0001465 48.0
HFD2_k127_3147886_4 Alpha/beta hydrolase family K06889 - - 0.0006047 49.0
HFD2_k127_3193361_0 FeS cluster assembly scaffold protein NifU K04488 - - 0.00000000000000000000000000000000008925 139.0
HFD2_k127_3193361_1 HEAT repeats - - - 0.00000000000000000002905 102.0
HFD2_k127_3210377_0 Glycine oxidase K03153 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19 0.000000000000000000000000000000000001122 146.0
HFD2_k127_3210377_1 cell redox homeostasis K03671 - - 0.000000000000000000000000214 121.0
HFD2_k127_3210377_2 Thioredoxin - - - 0.0000000000001385 81.0
HFD2_k127_3210377_3 Right handed beta helix region - - - 0.0004627 52.0
HFD2_k127_3227441_0 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 1.032e-233 750.0
HFD2_k127_3227441_1 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 419.0
HFD2_k127_3227441_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000006452 234.0
HFD2_k127_3227441_3 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000002099 201.0
HFD2_k127_3227441_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000002974 136.0
HFD2_k127_3227441_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000004938 132.0
HFD2_k127_3227441_6 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000002699 93.0
HFD2_k127_3227441_7 - - - - 0.00000000007249 67.0
HFD2_k127_3239046_0 Belongs to the 'phage' integrase family K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 320.0
HFD2_k127_3239046_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000002512 263.0
HFD2_k127_3239046_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000005241 163.0
HFD2_k127_3239046_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000009043 86.0
HFD2_k127_3244114_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000007879 263.0
HFD2_k127_3244114_1 Deoxynucleoside kinase K15518 - 2.7.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000003476 244.0
HFD2_k127_3244114_2 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000003954 59.0
HFD2_k127_325099_0 Cell division ATP-binding protein ftsE K09811,K09812 GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007171 271.0
HFD2_k127_325099_1 glycosyl transferase family 39 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000002341 209.0
HFD2_k127_325099_2 Dolichyl-phosphate-mannose-protein mannosyltransferase K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000003816 183.0
HFD2_k127_325099_3 transferase activity, transferring glycosyl groups K00754 - - 0.0000000000000000000000000000000008543 145.0
HFD2_k127_325099_4 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation K09811 - - 0.00000000000000001032 90.0
HFD2_k127_3251470_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 1.103e-307 964.0
HFD2_k127_3251470_1 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005657 283.0
HFD2_k127_3257632_0 Voltage gated chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 404.0
HFD2_k127_3257632_1 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 361.0
HFD2_k127_3264933_0 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 542.0
HFD2_k127_3264933_1 TIGR00266 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001129 253.0
HFD2_k127_3264933_2 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000002348 238.0
HFD2_k127_3264933_3 EVE domain - - - 0.00000000000000000000000000000000000000000008038 164.0
HFD2_k127_3270332_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001468 287.0
HFD2_k127_3270332_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000001609 96.0
HFD2_k127_3270332_2 Hypothetical methyltransferase - - - 0.00000000000000007426 91.0
HFD2_k127_3270332_3 Glycosyl transferase, family 2 - - - 0.0000003245 57.0
HFD2_k127_3278188_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 467.0
HFD2_k127_3278188_1 Redoxin - - - 0.0000000000000000000000000000000000000000003264 165.0
HFD2_k127_3284835_0 lipid A biosynthesis acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 374.0
HFD2_k127_3284835_1 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000000000000000002953 135.0
HFD2_k127_3284835_2 Beta-ketoacyl synthase, C-terminal domain K00647,K09458 - 2.3.1.179,2.3.1.41 0.0000000000000000000000000003631 123.0
HFD2_k127_3284835_3 radical SAM domain protein - - - 0.000000000000000000001192 95.0
HFD2_k127_3310110_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000005198 257.0
HFD2_k127_3310110_1 Protein involved in cellulose biosynthesis - - - 0.000000000000000000000000000000000001087 156.0
HFD2_k127_3310110_2 PFAM Polysaccharide deacetylase - - - 0.000000000000000000000000005604 124.0
HFD2_k127_3310110_3 fibronectin type III domain protein - - - 0.0000000000005874 79.0
HFD2_k127_3311633_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000223 145.0
HFD2_k127_3311633_1 Membrane - - - 0.000000002459 68.0
HFD2_k127_3311633_2 - - - - 0.00006996 56.0
HFD2_k127_333490_0 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000006156 143.0
HFD2_k127_333490_1 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000000004833 134.0
HFD2_k127_333490_2 - - - - 0.0000000000001811 75.0
HFD2_k127_3339522_0 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000247 297.0
HFD2_k127_3339522_1 AIR synthase related protein, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000121 201.0
HFD2_k127_3339522_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000005752 201.0
HFD2_k127_3344864_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 2.546e-204 663.0
HFD2_k127_3344864_1 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 318.0
HFD2_k127_3344864_2 Hydrolase, tatd K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000006412 243.0
HFD2_k127_3345260_0 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000002337 239.0
HFD2_k127_3345260_1 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000002178 138.0
HFD2_k127_3345260_2 serine threonine protein kinase - - - 0.00000000000000000000000000226 121.0
HFD2_k127_3352180_0 Heat shock protein 70 family - - - 5.793e-266 829.0
HFD2_k127_3352180_1 Belongs to the heat shock protein 70 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 412.0
HFD2_k127_3355177_0 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 304.0
HFD2_k127_3355177_1 Adenine glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000001548 233.0
HFD2_k127_3355177_2 D,D-heptose 1,7-bisphosphate phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000003058 176.0
HFD2_k127_3355177_3 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000001669 181.0
HFD2_k127_3355177_4 SIS domain K03271 - 5.3.1.28 0.00000000000000000000000000000000001518 142.0
HFD2_k127_3355177_5 PFAM GHMP kinase K07031 - 2.7.1.168 0.00000000000000004836 85.0
HFD2_k127_3380475_0 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000001492 231.0
HFD2_k127_3380475_1 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000000000000000000000005116 199.0
HFD2_k127_3380475_2 Branched-chain amino acid aminotransferase K00826 - 2.6.1.42 0.000000000000000000000000002864 115.0
HFD2_k127_3380475_3 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.0000000000000000001182 91.0
HFD2_k127_338680_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 4.31e-214 681.0
HFD2_k127_3387188_0 formate dehydrogenase (NAD+) activity K00336,K18006 - 1.12.1.2,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 376.0
HFD2_k127_3387188_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000001967 136.0
HFD2_k127_3412235_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 469.0
HFD2_k127_3423134_0 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 1.426e-262 820.0
HFD2_k127_3423571_0 adenosine deaminase K01488,K18286 GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.4.4,3.5.4.40 0.00000000000000000000000000000000000000000000000000000000002377 220.0
HFD2_k127_3423571_1 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000001087 167.0
HFD2_k127_3423571_2 COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K07720 - - 0.000000000002716 76.0
HFD2_k127_3426818_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000004765 175.0
HFD2_k127_3426818_1 DnaJ molecular chaperone homology domain - - - 0.0000000002231 72.0
HFD2_k127_3426818_2 Heat shock protein DnaJ domain protein - - - 0.0000001527 60.0
HFD2_k127_3448504_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005987 275.0
HFD2_k127_3448504_1 AraC family - - - 0.000000000000000000008574 104.0
HFD2_k127_3483190_0 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000001572 181.0
HFD2_k127_3483190_1 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000001454 96.0
HFD2_k127_3494527_0 Zinc metalloprotease (Elastase) K20274 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 346.0
HFD2_k127_3513985_0 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 311.0
HFD2_k127_3513985_1 Metallopeptidase family M24 K01262 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005933 280.0
HFD2_k127_3523486_0 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 424.0
HFD2_k127_3523486_1 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009529 363.0
HFD2_k127_3523486_2 SpoIVB peptidase S55 K00973,K02414,K21449 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006935 304.0
HFD2_k127_3523486_3 transport systems K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005195 252.0
HFD2_k127_3523486_4 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000002457 229.0
HFD2_k127_3523486_5 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000002035 174.0
HFD2_k127_3523486_6 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0000000000000000000002543 101.0
HFD2_k127_352733_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 303.0
HFD2_k127_352733_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000003791 258.0
HFD2_k127_352733_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000002372 232.0
HFD2_k127_352733_3 PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000006574 231.0
HFD2_k127_3531312_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K03737 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0016625,GO:0016903,GO:0043873,GO:0050896,GO:0055114 1.2.7.1 0.0 1162.0
HFD2_k127_3531312_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009637 424.0
HFD2_k127_3531312_2 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 307.0
HFD2_k127_3546615_0 Arginase family - - - 0.00000000000000000000000000000000000000000000000006257 190.0
HFD2_k127_3546615_1 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000008966 182.0
HFD2_k127_3546615_2 TIGRFAM TonB K03832 - - 0.000000006964 68.0
HFD2_k127_355070_0 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002211 280.0
HFD2_k127_355070_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate - - - 0.0000000000000000000000000000000000000000000000002496 184.0
HFD2_k127_355070_2 XanTHIne and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000000000000000000000000000007616 149.0
HFD2_k127_3554991_0 Belongs to the aldehyde dehydrogenase family K00128,K00130,K10217 - 1.2.1.3,1.2.1.32,1.2.1.8,1.2.1.85 9.092e-202 641.0
HFD2_k127_3554991_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000007156 180.0
HFD2_k127_3554991_2 Translation initiation inhibitor, yjgF family K15067 - 3.5.99.5 0.00000000000000000003298 106.0
HFD2_k127_3570738_0 Alpha-2-Macroglobulin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 571.0
HFD2_k127_357515_0 3-isopropylmalate dehydratase activity K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 4.107e-239 749.0
HFD2_k127_357515_1 MmgE/PrpD family K01720 - 4.2.1.79 2.615e-210 664.0
HFD2_k127_357515_2 mRNA catabolic process K06950,K09163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001247 259.0
HFD2_k127_357746_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000004121 196.0
HFD2_k127_357746_1 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000001916 181.0
HFD2_k127_3581142_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004564 292.0
HFD2_k127_3581142_1 CBS domain-containing protein K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002164 261.0
HFD2_k127_3581142_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000002167 188.0
HFD2_k127_3581142_3 Bacterial lipid A biosynthesis acyltransferase - - - 0.000000000000000000000000000000000001969 156.0
HFD2_k127_3581142_4 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000004201 88.0
HFD2_k127_3581142_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000003732 88.0
HFD2_k127_3590368_0 Putative metal-binding motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000563 299.0
HFD2_k127_3590368_1 FG-GAP repeat - - - 0.00003324 59.0
HFD2_k127_3629031_0 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000004017 124.0
HFD2_k127_3629031_1 - - - - 0.000000000001688 75.0
HFD2_k127_3629031_2 Putative regulatory protein - - - 0.000000002027 61.0
HFD2_k127_3629031_3 Patatin-like phospholipase K07001 - - 0.000000007006 62.0
HFD2_k127_3629031_4 Thioredoxin-like - - - 0.000001102 55.0
HFD2_k127_3629031_5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00003369 56.0
HFD2_k127_3645246_0 -O-antigen K07234 - - 0.0000000000004153 82.0
HFD2_k127_3645246_1 -O-antigen K02847,K13009 - - 0.0001352 52.0
HFD2_k127_3653882_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000005889 240.0
HFD2_k127_3653882_1 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000608 162.0
HFD2_k127_3653882_2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.00000000000000000000000000000004912 129.0
HFD2_k127_3653882_3 Hydrogenase maturation protease - - - 0.000000000000000000000000006671 120.0
HFD2_k127_3655121_0 mannitol 2-dehydrogenase activity K11690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008968 535.0
HFD2_k127_3655121_1 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 347.0
HFD2_k127_3655121_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 311.0
HFD2_k127_3655121_3 efflux transmembrane transporter activity - - - 0.0000000000000000001617 106.0
HFD2_k127_3655121_4 Tetratricopeptide repeat - - - 0.0000004624 60.0
HFD2_k127_3658569_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000628 420.0
HFD2_k127_3658569_1 Transposase - - - 0.00000000003552 71.0
HFD2_k127_3661068_0 COGs COG3278 Cbb3-type cytochrome oxidase subunit 1 K00404,K15862 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 553.0
HFD2_k127_3661068_1 cytochrome c oxidase K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000549 230.0
HFD2_k127_3661068_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000001499 221.0
HFD2_k127_3661068_3 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000002043 161.0
HFD2_k127_3661068_4 Protein of unknown function (DUF2934) - - - 0.00000006543 57.0
HFD2_k127_3661068_5 - - - - 0.00002999 51.0
HFD2_k127_3661068_6 Protein of unknown function (DUF2934) - - - 0.00003201 52.0
HFD2_k127_3673455_0 Family 5 K02035,K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 354.0
HFD2_k127_3673455_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000004634 125.0
HFD2_k127_3683477_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 1.172e-288 924.0
HFD2_k127_3683477_1 Catalyzes the reversible formation of glyoxylate and succinate from isocitrate K01637 - 4.1.3.1 0.00000000000000000000000000000000000000000000000000009928 202.0
HFD2_k127_3683477_2 Malate synthase K01638 - 2.3.3.9 0.00000000000000000000000000000000000000002883 158.0
HFD2_k127_3684449_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 595.0
HFD2_k127_3684449_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 286.0
HFD2_k127_3684449_2 nitric oxide dioxygenase activity - - - 0.00000000000000000000000004469 115.0
HFD2_k127_3686492_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 7.36e-322 998.0
HFD2_k127_3686492_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000966 139.0
HFD2_k127_3686492_2 Peptidase family M48 K03799 - - 0.0000000000000000000000002493 108.0
HFD2_k127_369920_0 Aldo Keto reductase K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 350.0
HFD2_k127_369920_1 regulation of methylation-dependent chromatin silencing K07454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001913 259.0
HFD2_k127_369920_2 PFAM band 7 protein - - - 0.0000000000000000000000000000009957 124.0
HFD2_k127_369920_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000001141 99.0
HFD2_k127_369920_4 Membrane protein implicated in regulation of membrane protease activity - - - 0.00000004274 61.0
HFD2_k127_371012_0 Peptidase M56 - - - 0.000000000000000000000000006153 126.0
HFD2_k127_371012_1 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.0004406 49.0
HFD2_k127_3739135_0 DUF1704 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007846 463.0
HFD2_k127_3739135_1 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 445.0
HFD2_k127_3739135_2 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 321.0
HFD2_k127_3739135_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 296.0
HFD2_k127_3739135_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000008323 162.0
HFD2_k127_3739135_5 Smr domain - - - 0.00000000000000000000000000000005569 128.0
HFD2_k127_3739135_6 lyase activity - - - 0.000000000001777 77.0
HFD2_k127_3739135_7 - - - - 0.00000004613 63.0
HFD2_k127_3741299_0 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000009616 207.0
HFD2_k127_3741299_1 HD domain - - - 0.0000000001724 73.0
HFD2_k127_3742610_0 cystathionine gamma-synthase activity K01739,K01758,K01760,K01761 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004121,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 411.0
HFD2_k127_3742610_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III - - - 0.0000000000000000000000000000000000000000000000000000000001027 216.0
HFD2_k127_3742610_2 CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000006718 109.0
HFD2_k127_374774_0 peptidase S9 prolyl oligopeptidase active site - GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 396.0
HFD2_k127_374774_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000006907 239.0
HFD2_k127_374774_2 BTB And C-terminal Kelch K10462 - - 0.0004495 54.0
HFD2_k127_3754926_0 phosphorelay signal transduction system K02437 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 474.0
HFD2_k127_3754926_1 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 410.0
HFD2_k127_3754926_2 phosphorelay signal transduction system K02437 - - 0.0000000000000000000008328 100.0
HFD2_k127_375798_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 2.293e-263 829.0
HFD2_k127_375798_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 460.0
HFD2_k127_375798_2 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 428.0
HFD2_k127_375798_3 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 317.0
HFD2_k127_375798_4 KH domain K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 301.0
HFD2_k127_375798_5 Involved in DNA repair and RecF pathway recombination K03474,K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 0.000000000000000000000000000000004216 138.0
HFD2_k127_375798_6 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000002794 109.0
HFD2_k127_3791749_0 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004192 278.0
HFD2_k127_3808373_0 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000003322 234.0
HFD2_k127_3808373_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000003898 192.0
HFD2_k127_3808373_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000005591 112.0
HFD2_k127_3812979_0 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000000003744 130.0
HFD2_k127_3812979_1 Zinc-binding dehydrogenase K00001 - 1.1.1.1 0.00000002491 55.0
HFD2_k127_381566_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000001242 213.0
HFD2_k127_381566_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000004192 171.0
HFD2_k127_381566_2 ABC-type branched-chain amino acid transport K01999 - - 0.000000000000005703 79.0
HFD2_k127_381566_3 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000004342 55.0
HFD2_k127_384203_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 491.0
HFD2_k127_384203_1 Metallo-beta-lactamase superfamily - GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002614 285.0
HFD2_k127_384203_2 PFAM Aldehyde dehydrogenase K00294 - 1.2.1.88 0.0000000000000000000000000000000000000000009954 156.0
HFD2_k127_384203_3 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.0000000000000000000000000000003093 126.0
HFD2_k127_384203_4 - - - - 0.000000000007312 78.0
HFD2_k127_3857760_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007799 300.0
HFD2_k127_3857760_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000006849 146.0
HFD2_k127_3857760_2 - - - - 0.000000000001072 79.0
HFD2_k127_3857760_3 Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation - GO:0005575,GO:0016020 - 0.0002482 51.0
HFD2_k127_3879675_0 Metallopeptidase family M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000002627 173.0
HFD2_k127_3879675_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000001071 115.0
HFD2_k127_3879675_2 Uncharacterised nucleotidyltransferase - - - 0.000001211 60.0
HFD2_k127_3880062_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 496.0
HFD2_k127_3880062_1 ABC 3 transport family K02075,K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006933 301.0
HFD2_k127_3880062_2 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002533 249.0
HFD2_k127_3880062_3 EamA-like transporter family - - - 0.00000000000000000000000000001122 130.0
HFD2_k127_3887116_0 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12980 - - 0.00000009843 64.0
HFD2_k127_3888878_0 Thrombospondin type 3 repeat - - - 0.0000000000000000000000000000000000000000001024 185.0
HFD2_k127_3888878_1 Protein of unknown function (DUF1573) - - - 0.000000004941 71.0
HFD2_k127_3888878_2 antibiotic catabolic process K01317,K02674,K07004,K11016,K13277,K20276,K21449 - 3.4.21.10 0.00005674 57.0
HFD2_k127_3905607_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000001003 195.0
HFD2_k127_3905607_1 - - - - 0.00000000007598 74.0
HFD2_k127_390995_0 dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000004776 236.0
HFD2_k127_390995_1 Abhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000574 225.0
HFD2_k127_390995_2 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000002307 192.0
HFD2_k127_3914699_0 ammonia-lyase activity K01745 - 4.3.1.3 1.418e-265 825.0
HFD2_k127_3914699_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000004659 152.0
HFD2_k127_3914699_2 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000000000000001909 114.0
HFD2_k127_3914699_3 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.000000000000000000000002771 109.0
HFD2_k127_3914699_4 oligosaccharyl transferase activity - - - 0.00000000000000000000004468 115.0
HFD2_k127_3914699_5 TGS domain K06944 - - 0.00000000000000287 76.0
HFD2_k127_3914699_6 Domain of unknown function (DUF4382) - - - 0.0000000000007915 76.0
HFD2_k127_3929600_0 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 371.0
HFD2_k127_3929600_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 300.0
HFD2_k127_3929600_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000002745 263.0
HFD2_k127_3929600_3 lipopolysaccharide transport K09774 - - 0.000000001022 71.0
HFD2_k127_3929600_4 Protein conserved in bacteria K11719 - - 0.00001738 57.0
HFD2_k127_3939409_0 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 310.0
HFD2_k127_3971903_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 371.0
HFD2_k127_3971903_1 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 335.0
HFD2_k127_3975497_0 diguanylate cyclase - - - 0.00003223 51.0
HFD2_k127_3990972_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 586.0
HFD2_k127_3990972_1 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 402.0
HFD2_k127_3990972_2 metal-dependent phosphohydrolase, HD sub domain K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000511 238.0
HFD2_k127_3997781_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 323.0
HFD2_k127_3997781_2 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000001409 60.0
HFD2_k127_4002101_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 415.0
HFD2_k127_4002101_1 histidine kinase, HAMP - - - 0.00000000000000000000000000000000000000000000004296 189.0
HFD2_k127_4002101_2 Macrocin-O-methyltransferase (TylF) - - - 0.0000000000000003025 90.0
HFD2_k127_4017830_0 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001791 284.0
HFD2_k127_4017830_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 - 0.0005536 46.0
HFD2_k127_4017905_0 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 492.0
HFD2_k127_4017905_1 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000000000000004938 159.0
HFD2_k127_4017905_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0002231 46.0
HFD2_k127_4024601_0 Phosphodiester glycosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 310.0
HFD2_k127_4024601_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000007301 201.0
HFD2_k127_4024601_2 Amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000002595 113.0
HFD2_k127_40276_0 serine-type endopeptidase activity K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 298.0
HFD2_k127_40276_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001475 291.0
HFD2_k127_40276_2 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000002643 190.0
HFD2_k127_40276_3 peptidylprolyl isomerase, FKBP-type K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000001795 178.0
HFD2_k127_40276_4 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000001322 105.0
HFD2_k127_40276_5 Glutathione S-transferase, C-terminal domain K00799,K03599 - 2.5.1.18 0.000000000000000000002031 104.0
HFD2_k127_4030869_0 Protein of unknown function (DUF2867) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 388.0
HFD2_k127_4030869_1 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009479 342.0
HFD2_k127_4035608_0 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 327.0
HFD2_k127_4035608_1 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.000000000000000000000000000000000006065 139.0
HFD2_k127_4036431_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000994 265.0
HFD2_k127_4036431_1 PFAM peptidase K16922 - - 0.0000000000000000000000000000000000000000000000000000000000000000116 251.0
HFD2_k127_4036431_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K16922 - - 0.0000000000000000000000000000000000000000000000517 193.0
HFD2_k127_4036431_3 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000003826 81.0
HFD2_k127_404447_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 2.465e-301 945.0
HFD2_k127_404447_1 methyltransferase - - - 0.0000000000000000000001987 98.0
HFD2_k127_4061349_0 May be involved in recombinational repair of damaged DNA K03631,K13582 GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 381.0
HFD2_k127_4061349_1 PFAM aminotransferase, class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 316.0
HFD2_k127_4061349_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000005974 218.0
HFD2_k127_4061349_3 MotA/TolQ/ExbB proton channel family K03561,K03562 - - 0.000000000000000000079 97.0
HFD2_k127_4063755_0 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002228 287.0
HFD2_k127_4063755_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000006886 238.0
HFD2_k127_4063755_2 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000004977 160.0
HFD2_k127_4063755_3 CDP-alcohol phosphatidyltransferase K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000001197 115.0
HFD2_k127_4063755_4 phosphatase activity K07025,K20862 - 3.1.3.102,3.1.3.104 0.00000000000000000004039 98.0
HFD2_k127_4063755_5 Domain of unknown function (DUF4388) - - - 0.000000000000000001055 100.0
HFD2_k127_4063755_6 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000008045 84.0
HFD2_k127_4065500_0 PFAM Formiminotransferase K00603 - 2.1.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 358.0
HFD2_k127_4065500_1 Glutamate-cysteine ligase family 2(GCS2) K01919 - 6.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 345.0
HFD2_k127_4065500_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000004382 178.0
HFD2_k127_4065500_3 B12 binding domain - - - 0.00000000000000000000000000000000000000004974 162.0
HFD2_k127_4065500_4 acyl carrier protein K02078 - - 0.00000000000000000005235 92.0
HFD2_k127_4065500_5 PEGA domain K15539 - - 0.0000000009312 69.0
HFD2_k127_4065500_6 DnaJ-class molecular chaperone with C-terminal Zn finger domain - - - 0.0005898 51.0
HFD2_k127_4082043_0 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000001513 191.0
HFD2_k127_4082043_1 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000002175 172.0
HFD2_k127_4088794_0 O-linked GlcNAc transferase-putative TPR-containing transmembrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000003542 235.0
HFD2_k127_4088794_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000009227 129.0
HFD2_k127_4093273_0 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 353.0
HFD2_k127_4093273_1 Flavin containing amine oxidoreductase K00231,K01854 - 1.3.3.15,1.3.3.4,5.4.99.9 0.000000000000000000000000000000000000000000000000000000000000000000004976 240.0
HFD2_k127_4093273_2 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000001103 125.0
HFD2_k127_4093587_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007393 480.0
HFD2_k127_4121704_0 Glycine cleavage T-protein C-terminal barrel domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 402.0
HFD2_k127_4121704_1 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000001682 112.0
HFD2_k127_4121788_0 Outer membrane receptor - - - 0.000000000000000000000000004493 124.0
HFD2_k127_4121788_1 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000001083 113.0
HFD2_k127_4121788_3 - - - - 0.0007 43.0
HFD2_k127_4138457_0 Peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 334.0
HFD2_k127_4138457_1 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000001692 132.0
HFD2_k127_4140549_0 PFAM Cys Met metabolism K01740 - 2.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009368 524.0
HFD2_k127_4188935_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 548.0
HFD2_k127_4188935_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 411.0
HFD2_k127_4188935_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621,K21576,K21577 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.21.4.2,1.21.4.3,1.21.4.4,2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 379.0
HFD2_k127_4188935_3 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 336.0
HFD2_k127_4188935_4 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009073 298.0
HFD2_k127_4188935_5 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000102 264.0
HFD2_k127_4188935_6 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000006177 237.0
HFD2_k127_4188935_7 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000141 110.0
HFD2_k127_4193625_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 354.0
HFD2_k127_4193625_1 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000001376 136.0
HFD2_k127_4193625_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000006125 79.0
HFD2_k127_4193625_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000002416 67.0
HFD2_k127_4211951_0 transcriptional regulator - - - 0.0000000000000000000000000006668 121.0
HFD2_k127_4211951_1 Tetratricopeptide repeat - - - 0.0000000000000000001623 103.0
HFD2_k127_4211951_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.000000006388 61.0
HFD2_k127_4220159_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 307.0
HFD2_k127_4220159_1 Oxygen tolerance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000117 284.0
HFD2_k127_4220159_2 tetratricopeptide repeat - - - 0.00000000000000000000000000000004117 142.0
HFD2_k127_4220159_3 peptidyl-tyrosine sulfation K07114 - - 0.000000000000000000003254 102.0
HFD2_k127_4226021_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 306.0
HFD2_k127_4226021_1 sulfurtransferase activity K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000002491 252.0
HFD2_k127_4248436_0 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003678 242.0
HFD2_k127_4248436_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000002659 62.0
HFD2_k127_4248436_2 Anti-sigma-K factor rskA - - - 0.000006955 58.0
HFD2_k127_4260632_0 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 302.0
HFD2_k127_4260632_1 PFAM Roadblock LC7 family protein - - - 0.000000000000000000000000000000000000000000000000007439 185.0
HFD2_k127_4260632_2 PFAM TonB-dependent Receptor - - - 0.00000001661 61.0
HFD2_k127_4274212_0 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000005326 150.0
HFD2_k127_4274212_1 Carboxypeptidase regulatory-like domain - - - 0.000000001324 69.0
HFD2_k127_4274406_0 PPIC-type PPIASE domain K02597,K03769,K03771 - 5.2.1.8 0.000000000000000000000000000000006413 139.0
HFD2_k127_427828_0 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 441.0
HFD2_k127_427828_1 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000000000000000000000001825 167.0
HFD2_k127_427828_2 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K21142 - 2.8.1.12 0.000000000000000000000000000000001896 136.0
HFD2_k127_427828_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.000000000000000000000000000000005295 131.0
HFD2_k127_427828_4 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K21142 - 2.8.1.12 0.00000000007519 67.0
HFD2_k127_4285852_0 Peptidase, M50 family K16922 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007353 520.0
HFD2_k127_4285852_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000003796 162.0
HFD2_k127_4290178_0 Histidine kinase K02668,K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000001567 228.0
HFD2_k127_4291419_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 491.0
HFD2_k127_4305039_0 PFAM Cytochrome b b6 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 415.0
HFD2_k127_4305039_1 Cytochrome b(C-terminal)/b6/petD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 397.0
HFD2_k127_4305039_2 Cytochrome c - - - 0.00000001263 64.0
HFD2_k127_4314140_0 TamB, inner membrane protein subunit of TAM complex K07277,K09800 - - 0.0000000000003858 82.0
HFD2_k127_4326396_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 4.495e-241 758.0
HFD2_k127_4326396_1 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 489.0
HFD2_k127_4326396_2 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 451.0
HFD2_k127_4326396_3 CorA-like Mg2+ transporter protein K03284 GO:0000041,GO:0000287,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015087,GO:0015095,GO:0015318,GO:0015693,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0050897,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070838,GO:0071840,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008061 401.0
HFD2_k127_4326396_4 Sugar-transfer associated ATP-grasp - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002749 274.0
HFD2_k127_4326396_5 Putative adhesin - - - 0.00000000000000000000000003498 121.0
HFD2_k127_4346274_0 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000002637 195.0
HFD2_k127_4346274_1 Molybdate ABC transporter K02018 - - 0.000000000000000000000000000000000002059 145.0
HFD2_k127_4346274_2 Protein of unknown function, DUF255 K06888 - - 0.000005686 53.0
HFD2_k127_4353092_0 PFAM MazG nucleotide pyrophosphohydrolase K02499,K04765 - 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000002004 221.0
HFD2_k127_4353092_1 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000001458 217.0
HFD2_k127_4353092_2 Tetratricopeptide repeat - - - 0.0000000000000000000000194 117.0
HFD2_k127_4353092_3 Domain of unknown function (DUF1844) - - - 0.000000000000002053 82.0
HFD2_k127_4355271_0 pilus organization K02674,K07004 - - 0.000005192 58.0
HFD2_k127_4367624_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1349.0
HFD2_k127_4367624_1 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 340.0
HFD2_k127_4367624_2 Domain of unknown function (DUF1956) - - - 0.000000000000000000000001551 112.0
HFD2_k127_4373488_0 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000007765 240.0
HFD2_k127_4373488_1 FAD linked oxidases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000001264 187.0
HFD2_k127_4373488_2 Hexapeptide repeat of succinyl-transferase K02617 - - 0.000000000000000000000000000000000000000000000001559 179.0
HFD2_k127_4373488_3 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.00000000000000000000000000000000001303 140.0
HFD2_k127_4373488_4 Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009893,GO:0009987,GO:0019216,GO:0019222,GO:0019747,GO:0031323,GO:0031325,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045828,GO:0045834,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:0080090,GO:1901576 - 0.00000000000000000000000000000004859 134.0
HFD2_k127_4375466_0 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000004122 243.0
HFD2_k127_4375466_1 competence protein - - - 0.000000000000000001102 93.0
HFD2_k127_4379323_0 PFAM MMPL family K07003 - - 5.136e-221 709.0
HFD2_k127_4379323_1 protein conserved in bacteria - - - 0.000000000000000001023 100.0
HFD2_k127_4396803_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 466.0
HFD2_k127_4396803_1 Sulfatase - - - 0.0000000000000000000000000000000001259 141.0
HFD2_k127_4405577_0 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 428.0
HFD2_k127_4405577_1 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006675 291.0
HFD2_k127_4405577_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000001173 163.0
HFD2_k127_4405577_3 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000005004 91.0
HFD2_k127_4424785_0 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K16950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 448.0
HFD2_k127_4424785_1 2 iron, 2 sulfur cluster binding K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004457 253.0
HFD2_k127_4424785_2 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000000000000000000000000000000000002127 175.0
HFD2_k127_4424785_3 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000213 158.0
HFD2_k127_4473981_0 protein-disulfide reductase activity K04084,K06196 - 1.8.1.8 0.00000000000000000823 91.0
HFD2_k127_4491246_0 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000003186 217.0
HFD2_k127_4493838_0 PA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 521.0
HFD2_k127_4493838_1 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 462.0
HFD2_k127_4493838_2 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 323.0
HFD2_k127_4493838_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000002666 263.0
HFD2_k127_4493838_4 bacterial OsmY and nodulation domain - - - 0.000000000000002725 87.0
HFD2_k127_450426_0 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.00000000000000000000000000000000000000000000003024 181.0
HFD2_k127_450426_1 Domain of unknown function (DUF1848) - - - 0.000000000000000000000000000000000000000000007257 170.0
HFD2_k127_450426_2 BlaR1 peptidase M56 K02172,K02547 - - 0.00005823 51.0
HFD2_k127_4504599_0 helicase activity - - - 1.908e-293 923.0
HFD2_k127_4504599_1 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000082 277.0
HFD2_k127_4504599_2 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000001302 151.0
HFD2_k127_4504599_3 Protein of unknown function, DUF481 - - - 0.000006599 57.0
HFD2_k127_4506113_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000129 112.0
HFD2_k127_4506113_1 3-hydroxyanthranilic acid dioxygenase K00452 - 1.13.11.6 0.00000000000003694 74.0
HFD2_k127_4509261_0 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 377.0
HFD2_k127_4509261_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002642 286.0
HFD2_k127_4509261_2 Ribonuclease E/G family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000001414 178.0
HFD2_k127_4509261_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000000000000000000000005584 168.0
HFD2_k127_4509261_4 hydrolase of the alpha beta K07018 - - 0.00000000000000000000000000000000000000003209 165.0
HFD2_k127_4509261_5 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000009691 93.0
HFD2_k127_4509261_6 A G-specific adenine glycosylase K03575 - - 0.00000000002399 69.0
HFD2_k127_4510637_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 4.828e-248 773.0
HFD2_k127_4510637_1 Carbamoyl-phosphate synthetase large chain domain protein K01968 - 6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000002058 246.0
HFD2_k127_451446_0 Protein kinase domain K12132 - 2.7.11.1 1.837e-232 760.0
HFD2_k127_451446_1 GAF domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 361.0
HFD2_k127_451446_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000152 264.0
HFD2_k127_4521846_0 FAD binding domain K00103,K00279 - 1.1.3.8,1.5.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 346.0
HFD2_k127_4521846_1 LytB protein K03527 - 1.17.7.4 0.00000000000000000000000002258 110.0
HFD2_k127_4532434_0 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 321.0
HFD2_k127_4532434_1 carboxypeptidase activity K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000002576 228.0
HFD2_k127_4532434_2 Ankyrin repeat - - - 0.000000000000000000000000000000000000000004482 162.0
HFD2_k127_4532434_3 Peptidase M56 - - - 0.000000000000000000000002585 118.0
HFD2_k127_4555473_0 Coenzyme A transferase K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 347.0
HFD2_k127_4555473_1 PFAM Coenzyme A transferase K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000014 278.0
HFD2_k127_4555473_2 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000001008 193.0
HFD2_k127_4555473_3 Glyoxalase-like domain K05606 - 5.1.99.1 0.0000000000000000000000001182 110.0
HFD2_k127_4555473_4 - - - - 0.0000000000000000005342 90.0
HFD2_k127_4555473_5 (FHA) domain - - - 0.00000000000004848 82.0
HFD2_k127_4559017_0 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 348.0
HFD2_k127_4559017_1 Glycosyl transferase, group 1 family protein - - - 0.00000000000000000000000000001564 130.0
HFD2_k127_4578334_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 431.0
HFD2_k127_4578334_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 363.0
HFD2_k127_4578334_2 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000008398 239.0
HFD2_k127_4578334_3 Cytochrome c biogenesis protein transmembrane region K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000004822 239.0
HFD2_k127_4578334_4 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000003543 205.0
HFD2_k127_4578334_5 belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000578 125.0
HFD2_k127_4578334_6 Glutathione peroxidase K02199 - - 0.00000000000000000003721 103.0
HFD2_k127_4578334_7 Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000991 54.0
HFD2_k127_4578334_8 Helix-turn-helix domain K07729 - - 0.0001367 48.0
HFD2_k127_4580283_0 FAD dependent oxidoreductase K00109 - 1.1.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 451.0
HFD2_k127_4580283_1 Metallo-peptidase family M12B Reprolysin-like - - - 0.000000000000000000005655 100.0
HFD2_k127_4580283_2 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000006696 76.0
HFD2_k127_4601219_0 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000001056 205.0
HFD2_k127_460892_0 catalyzes the conversion of acetate and CoA to acetyl-CoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 612.0
HFD2_k127_460892_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 538.0
HFD2_k127_460892_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000007689 66.0
HFD2_k127_460892_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.0002795 52.0
HFD2_k127_461629_0 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 326.0
HFD2_k127_461629_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005009 258.0
HFD2_k127_461629_2 UMP kinase activity K09903 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000399 245.0
HFD2_k127_461629_3 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000004769 93.0
HFD2_k127_4639813_0 Peptidase, M16 K07263,K07623 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 502.0
HFD2_k127_4639813_1 PFAM Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 452.0
HFD2_k127_4639813_2 HhH-GPD superfamily base excision DNA repair protein - - - 0.000000000000001341 83.0
HFD2_k127_4639813_3 secondary active sulfate transmembrane transporter activity K06901 - - 0.0000005909 54.0
HFD2_k127_4650362_0 alanine dehydrogenase activity K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 311.0
HFD2_k127_4650362_1 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004809 256.0
HFD2_k127_4650362_2 Domain of Unknown Function (DUF349) - - - 0.000000000000000000000000000000000000000000000000000000000000000005779 252.0
HFD2_k127_4650362_3 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.00000000000005717 86.0
HFD2_k127_4651659_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 385.0
HFD2_k127_4651659_1 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000588 203.0
HFD2_k127_4651659_2 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 GO:0008150,GO:0009605,GO:0009607,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 1.6.5.3 0.00001158 48.0
HFD2_k127_4679076_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 432.0
HFD2_k127_4679076_1 Sulfotransferase domain - - - 0.000391 51.0
HFD2_k127_4682159_0 PFAM UBA THIF-type NAD FAD binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 472.0
HFD2_k127_4682159_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 481.0
HFD2_k127_4682159_2 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000006764 223.0
HFD2_k127_4682159_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000001482 212.0
HFD2_k127_4682159_4 Sulfatase - - - 0.00000000000000000000000000000001582 146.0
HFD2_k127_4682159_5 Mov34 MPN PAD-1 family protein - - - 0.0000000000000000000000000000004298 128.0
HFD2_k127_4682159_7 ASPIC and UnbV - - - 0.0007745 42.0
HFD2_k127_469174_0 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 340.0
HFD2_k127_469174_1 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 294.0
HFD2_k127_469174_2 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000004373 213.0
HFD2_k127_469174_3 protein conserved in bacteria K09931 - - 0.00000000000000000000000000000000003484 143.0
HFD2_k127_469174_4 Belongs to the UPF0178 family K09768 - - 0.000000000000000000000000000000001181 135.0
HFD2_k127_469174_5 Nodulation protein S (NodS) - - - 0.000000000000000007686 96.0
HFD2_k127_469174_6 Carboxymuconolactone decarboxylase family - - - 0.0000000000000001785 82.0
HFD2_k127_469174_7 Carboxymuconolactone decarboxylase family - - - 0.0000000000001 74.0
HFD2_k127_469174_8 Thiol-disulfide isomerase and - - - 0.0004912 51.0
HFD2_k127_4715798_0 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000518 251.0
HFD2_k127_472486_0 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 287.0
HFD2_k127_472486_1 Outer membrane receptor K02014,K16087 - - 0.000000000000000000000000000000000000000000000000000000000000000003188 244.0
HFD2_k127_472486_2 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000004498 243.0
HFD2_k127_472486_3 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000002991 86.0
HFD2_k127_472486_4 Peptidase family M1 domain - - - 0.000000491 63.0
HFD2_k127_472517_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 317.0
HFD2_k127_472517_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001236 294.0
HFD2_k127_472517_10 TonB C terminal - - - 0.000000000000005308 86.0
HFD2_k127_472517_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005593 286.0
HFD2_k127_472517_3 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000009821 245.0
HFD2_k127_472517_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02372,K02535,K13599,K16363 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 3.5.1.108,4.2.1.59 0.000000000000000000000000000000000000000000000000001006 188.0
HFD2_k127_472517_5 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000000000000008414 151.0
HFD2_k127_472517_6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000002434 157.0
HFD2_k127_472517_7 Thrombospondin type 3 repeat - - - 0.00000000000000000000000000000000067 153.0
HFD2_k127_472517_8 TIGRFAM tol-pal system protein YbgF - - - 0.0000000000000000000004606 108.0
HFD2_k127_472517_9 positive regulation of growth rate - - - 0.000000000000000005547 91.0
HFD2_k127_4726006_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 332.0
HFD2_k127_4726006_1 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000002557 244.0
HFD2_k127_4726006_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000002811 157.0
HFD2_k127_4746890_0 Peptidase family M1 domain - - - 1.689e-263 824.0
HFD2_k127_4746890_1 oligopeptide transporter, OPT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004255 264.0
HFD2_k127_4746890_2 PFAM Aminotransferase class I and II K00814 - 2.6.1.2 0.00000000000000000000000000000000000000004744 153.0
HFD2_k127_4750610_0 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000000000000007678 202.0
HFD2_k127_4750610_1 Iron-sulfur cluster assembly protein - - - 0.00000000000000000000000000000000001041 145.0
HFD2_k127_4769125_0 Carbon starvation protein K06200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 548.0
HFD2_k127_4769125_1 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.00000000000000000000000000000000000000000000000001328 189.0
HFD2_k127_4769125_2 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000009075 173.0
HFD2_k127_4769125_3 Carbon starvation protein K06200 - - 0.0000000000000000000000000000000008779 131.0
HFD2_k127_4769125_4 Protein of unknown function (DUF3467) - - - 0.00000000000000000002916 96.0
HFD2_k127_4769125_5 chaperone-mediated protein folding - GO:0003674,GO:0003756,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016043,GO:0016787,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0022607,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043163,GO:0043165,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044464,GO:0045229,GO:0046872,GO:0051603,GO:0061024,GO:0061077,GO:0070011,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.00001553 55.0
HFD2_k127_4801290_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 417.0
HFD2_k127_4801290_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002568 256.0
HFD2_k127_4801290_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000006264 189.0
HFD2_k127_4801290_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.000000000000000006448 90.0
HFD2_k127_480965_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 338.0
HFD2_k127_480965_1 SpoU rRNA Methylase family K03437 - - 0.000000000000000000000000000000000000000000491 168.0
HFD2_k127_480965_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000001214 155.0
HFD2_k127_4832057_0 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008572 507.0
HFD2_k127_4832057_1 His Kinase A (phosphoacceptor) domain K13598 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 492.0
HFD2_k127_4832057_2 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000001967 137.0
HFD2_k127_4832057_3 transcriptional regulator, Rrf2 family - - - 0.0000000000000000000001707 108.0
HFD2_k127_4832057_4 Domain of unknown function (DUF4390) - - - 0.0000001687 59.0
HFD2_k127_483220_0 Large extracellular alpha-helical protein K06894 - - 0.0 1025.0
HFD2_k127_4834036_0 SMART PAS domain containing protein - - - 0.000000000000000000000000000000000000000000000000007434 206.0
HFD2_k127_4834036_1 EAL domain - - - 0.00000004705 55.0
HFD2_k127_4838310_0 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000005475 237.0
HFD2_k127_4838310_1 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.000000000000000000000000000000000004144 138.0
HFD2_k127_4838310_2 Belongs to the GcvT family K00605,K06980 - 2.1.2.10 0.00000000000000000000000000000003639 133.0
HFD2_k127_4838310_3 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000008836 129.0
HFD2_k127_4838310_4 Subtilase family - - - 0.0000001179 64.0
HFD2_k127_4848855_0 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000008816 231.0
HFD2_k127_4848855_1 YCII-related domain - - - 0.0000000002893 66.0
HFD2_k127_4848855_2 tetratricopeptide repeat - - - 0.000009098 59.0
HFD2_k127_4848855_3 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000095 55.0
HFD2_k127_4848855_4 Putative prokaryotic signal transducing protein - - - 0.00002144 51.0
HFD2_k127_4848855_5 O-Antigen ligase - - - 0.0001094 55.0
HFD2_k127_4855549_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 2.553e-247 783.0
HFD2_k127_4855549_1 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000002201 128.0
HFD2_k127_4855549_2 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.00000000000000002167 93.0
HFD2_k127_4856993_0 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007703 432.0
HFD2_k127_4856993_1 Dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 321.0
HFD2_k127_4856993_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 319.0
HFD2_k127_4856993_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.000000000006504 78.0
HFD2_k127_4864219_0 NADH dehydrogenase (ubiquinone) activity K14089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 496.0
HFD2_k127_4864219_1 Proton-conducting membrane transporter K12141 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033554,GO:0044425,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009888 405.0
HFD2_k127_4864219_2 Hydrogenase 4 membrane K12140 GO:0008150,GO:0040007 - 0.0000000000000000000000000000000001202 138.0
HFD2_k127_4867728_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 552.0
HFD2_k127_4867728_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000003812 232.0
HFD2_k127_4867728_2 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000007007 105.0
HFD2_k127_4902148_0 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000001812 166.0
HFD2_k127_4902148_1 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000000000000000000007294 156.0
HFD2_k127_4902148_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000000000000000007842 113.0
HFD2_k127_4910812_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 481.0
HFD2_k127_4910812_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000006782 258.0
HFD2_k127_4910812_2 Regulatory protein, FmdB - - - 0.000000000000000000000176 103.0
HFD2_k127_4914530_0 Belongs to the MurCDEF family K01921,K01924,K02558 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0042802,GO:0044424,GO:0044464 6.3.2.4,6.3.2.45,6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 481.0
HFD2_k127_4914530_1 MotA TolQ ExbB proton channel K03561,K03562 - - 0.000000000000000000000000000000000000000000000000000000000000004285 224.0
HFD2_k127_4914530_2 TIGRFAM TonB K03832 - - 0.000000000000000000000002187 112.0
HFD2_k127_4914530_3 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.000000000000000000000003659 107.0
HFD2_k127_4914530_4 Tetratricopeptide repeat - - - 0.00000000000000000000001296 112.0
HFD2_k127_4914530_5 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000219 106.0
HFD2_k127_4914530_6 - - - - 0.0000000000001825 82.0
HFD2_k127_4923250_0 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 502.0
HFD2_k127_4923250_1 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 314.0
HFD2_k127_4923250_2 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.0000000000000000000000000000000000000000000000000000001069 203.0
HFD2_k127_4923250_3 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000001405 190.0
HFD2_k127_4923250_4 PFAM Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000000000000002904 175.0
HFD2_k127_4923250_5 Bacterial PH domain - - - 0.000000000000000000000000000000000000001178 152.0
HFD2_k127_4923250_6 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000005156 129.0
HFD2_k127_4932701_0 YidE YbjL duplication domain protein K07085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 441.0
HFD2_k127_4954977_0 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000008213 189.0
HFD2_k127_4954977_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000007756 141.0
HFD2_k127_4954977_2 Sulfotransferase family - - - 0.0000000000001106 80.0
HFD2_k127_4959581_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000001837 137.0
HFD2_k127_4963807_0 cheY-homologous receiver domain K03413 - - 0.000000000000000000005127 108.0
HFD2_k127_4966909_0 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000006473 180.0
HFD2_k127_4966909_1 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000000000001238 138.0
HFD2_k127_4973540_0 GTP-binding protein TypA K06207 - - 7.033e-243 764.0
HFD2_k127_4973540_1 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 523.0
HFD2_k127_4973540_2 Glycerophosphodiester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000002129 109.0
HFD2_k127_4973540_3 methyltransferase - - - 0.0000000000000001485 86.0
HFD2_k127_4973540_4 ThiS family K03636 - - 0.0000000000002133 76.0
HFD2_k127_4974134_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 8.837e-201 636.0
HFD2_k127_4974134_1 Iron dependent repressor, metal binding and dimerisation domain K03709 - - 0.00000000000000000000000000000000000000001585 160.0
HFD2_k127_4978573_0 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000000000000000000004962 213.0
HFD2_k127_4978573_1 CYTH K05873 - 4.6.1.1 0.00000000000000000000001936 108.0
HFD2_k127_5007334_0 General secretory system II, protein E domain protein K02652 - - 0.000000000000000000000000000000000000000004278 157.0
HFD2_k127_5007334_1 Mannosyltransferase (PIG-V) - - - 0.00000000000000000000000000000000000002872 158.0
HFD2_k127_5007334_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000002311 94.0
HFD2_k127_5007334_3 - - - - 0.000000001223 70.0
HFD2_k127_5021614_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.581e-231 727.0
HFD2_k127_5021614_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 434.0
HFD2_k127_5021614_2 NUBPL iron-transfer P-loop NTPase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 314.0
HFD2_k127_5021614_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 307.0
HFD2_k127_5021614_4 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000001014 186.0
HFD2_k127_5021614_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000003522 113.0
HFD2_k127_5021614_6 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000000000000000002851 102.0
HFD2_k127_5021614_7 Belongs to the ParB family K03497 - - 0.00000000004101 66.0
HFD2_k127_5021614_8 Polymer-forming cytoskeletal - - - 0.0000000001658 68.0
HFD2_k127_5021614_9 Putative single-stranded nucleic acids-binding domain K06346 - - 0.0000007178 51.0
HFD2_k127_5030268_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 473.0
HFD2_k127_5030268_1 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 396.0
HFD2_k127_5030268_2 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 369.0
HFD2_k127_5030268_3 pfam abc K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 286.0
HFD2_k127_5030268_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000001379 192.0
HFD2_k127_5030268_5 Indole-3-glycerol phosphate synthase K01609 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48 0.0000000000000000000000000000000000000000000001702 180.0
HFD2_k127_5030268_6 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000001235 145.0
HFD2_k127_5030268_7 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000007703 134.0
HFD2_k127_5047294_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.228e-277 883.0
HFD2_k127_5047294_1 Hfq protein - - - 0.00000000000000000000001055 105.0
HFD2_k127_5047294_2 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000008498 100.0
HFD2_k127_5047294_3 SurA N-terminal domain K03769 - 5.2.1.8 0.0000000000000002465 90.0
HFD2_k127_5054906_0 Phosphate acyltransferases K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000238 289.0
HFD2_k127_5054906_1 conserved protein UCP033924 - - - 0.00000000000000000000000000000000000000000003717 166.0
HFD2_k127_5054906_2 (FHA) domain - - - 0.0000000004787 71.0
HFD2_k127_5069243_0 Belongs to the peptidase S8 family - - - 6.008e-194 631.0
HFD2_k127_5069243_1 Bacitracin resistance protein BacA K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 292.0
HFD2_k127_5082653_0 Cys/Met metabolism PLP-dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003314 286.0
HFD2_k127_5082653_1 Tetratricopeptide repeat - - - 0.000000000000000001365 100.0
HFD2_k127_5087260_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 342.0
HFD2_k127_5087260_1 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000004513 177.0
HFD2_k127_5087260_2 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000008675 117.0
HFD2_k127_5101657_0 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 357.0
HFD2_k127_5101657_1 ABC-type multidrug transport system ATPase and permease K06147 - - 0.000000000000000000000000000000006556 136.0
HFD2_k127_5101657_2 signal peptide processing K03100,K12062,K13280 - 3.4.21.89 0.0009906 45.0
HFD2_k127_5101897_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0 1006.0
HFD2_k127_5105151_0 Oligoendopeptidase f - - - 1.306e-257 814.0
HFD2_k127_5105151_1 Chemotaxis protein histidine kinase and related kinases K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 520.0
HFD2_k127_5105151_2 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000002564 164.0
HFD2_k127_5105151_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000008046 154.0
HFD2_k127_5105151_4 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000000001169 155.0
HFD2_k127_5105151_5 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000001868 154.0
HFD2_k127_5105151_6 Gaf domain K07814 - - 0.00000000000000000000000000000000006656 144.0
HFD2_k127_5105151_7 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000001067 130.0
HFD2_k127_5105151_8 Domain present in phytochromes and cGMP-specific phosphodiesterases. K03407 - 2.7.13.3 0.0000000000000008944 90.0
HFD2_k127_5105151_9 Domain of unknown function (DUF4388) - - - 0.000000003249 68.0
HFD2_k127_5121108_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000003941 132.0
HFD2_k127_5121108_1 response regulator K02481 - - 0.000000000000000000000000000002294 125.0
HFD2_k127_5121108_2 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000003702 67.0
HFD2_k127_513786_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 496.0
HFD2_k127_513786_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 394.0
HFD2_k127_513786_10 SLBB domain K02237 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000002732 93.0
HFD2_k127_513786_11 PFAM metal-dependent phosphohydrolase, HD sub domain K01524,K06950 - 3.6.1.11,3.6.1.40 0.0000001125 64.0
HFD2_k127_513786_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 391.0
HFD2_k127_513786_3 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006341 329.0
HFD2_k127_513786_4 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 302.0
HFD2_k127_513786_5 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000003844 265.0
HFD2_k127_513786_6 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000000000000000000000000000000000000000000000004296 205.0
HFD2_k127_513786_7 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000005904 169.0
HFD2_k127_513786_8 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000008546 156.0
HFD2_k127_513786_9 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000000000000001408 145.0
HFD2_k127_5146953_0 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 499.0
HFD2_k127_5146953_1 PFAM D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000001366 222.0
HFD2_k127_5146953_2 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000006475 189.0
HFD2_k127_5154264_0 arylsulfatase A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000689 273.0
HFD2_k127_5154264_1 PEP-utilising enzyme, mobile domain - - - 0.00000000000000000000000000000000000007335 157.0
HFD2_k127_5167955_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.22e-212 668.0
HFD2_k127_5167955_1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002427 252.0
HFD2_k127_5167955_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000002541 237.0
HFD2_k127_5177151_0 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008391 356.0
HFD2_k127_5177151_1 von Willebrand factor (vWF) type A domain K07114,K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 349.0
HFD2_k127_5177151_2 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 290.0
HFD2_k127_5177151_3 ATPase associated with various cellular K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006271 243.0
HFD2_k127_5177151_4 subunit of a heme lyase K02198,K02200,K04016,K04017,K04018 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564 - 0.000000000000000000000000006341 123.0
HFD2_k127_5178903_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000001801 179.0
HFD2_k127_5178903_1 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000002711 78.0
HFD2_k127_5186367_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 527.0
HFD2_k127_5186367_1 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.00000000000000000008938 96.0
HFD2_k127_5195170_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.501e-195 618.0
HFD2_k127_5195170_1 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000001578 174.0
HFD2_k127_5196113_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.168e-283 891.0
HFD2_k127_5196113_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 329.0
HFD2_k127_5201270_0 Polysaccharide biosynthesis protein K17947 - 5.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 373.0
HFD2_k127_5201270_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 346.0
HFD2_k127_5201270_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001464 293.0
HFD2_k127_5201270_3 PFAM lipopolysaccharide biosynthesis protein K16554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001282 275.0
HFD2_k127_5214905_0 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.00000000000000000000000000000001496 136.0
HFD2_k127_5214905_1 ATPase-coupled phosphate ion transmembrane transporter activity - - - 0.0000000005131 70.0
HFD2_k127_5217324_0 MFS_1 like family K08161 - - 0.000000000000000000000000000000000000000000000007839 190.0
HFD2_k127_5217324_1 L-asparaginase II - - - 0.00000000000000004867 83.0
HFD2_k127_52200_0 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 374.0
HFD2_k127_5228411_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 605.0
HFD2_k127_5228411_1 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000833 195.0
HFD2_k127_5238464_0 tRNA pseudouridine synthase K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000002642 194.0
HFD2_k127_5238464_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000107 87.0
HFD2_k127_5238464_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000282 76.0
HFD2_k127_5241870_0 Protein of unknown function (DUF3617) - - - 0.000000000000000005324 98.0
HFD2_k127_524535_0 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 449.0
HFD2_k127_524535_1 COG3901 Regulator of nitric oxide reductase transcription K19339,K19343 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 302.0
HFD2_k127_524535_2 Memo-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003992 275.0
HFD2_k127_524535_3 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005285 254.0
HFD2_k127_5252782_0 symbiont process K00612 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 485.0
HFD2_k127_5252782_1 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 466.0
HFD2_k127_5252782_10 O-Antigen ligase - - - 0.0000000000003641 82.0
HFD2_k127_5252782_11 transferase activity, transferring glycosyl groups - - - 0.000000000002955 81.0
HFD2_k127_5252782_12 repeat-containing protein - - - 0.0000000001472 73.0
HFD2_k127_5252782_2 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004465 269.0
HFD2_k127_5252782_3 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002116 267.0
HFD2_k127_5252782_4 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000001656 193.0
HFD2_k127_5252782_5 O-Antigen ligase K02847 - - 0.0000000000000000000000000000000000000003044 168.0
HFD2_k127_5252782_6 Membrane protein involved in the export of o-antigen and teichoic acid K03328 - - 0.00000000000000000000000000000000000005138 165.0
HFD2_k127_5252782_7 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000004492 116.0
HFD2_k127_5252782_8 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000009679 106.0
HFD2_k127_5252782_9 TIGRFAM FemAB-related protein, PEP-CTERM - - - 0.00000000000007161 83.0
HFD2_k127_525811_0 methyltransferase - - - 0.00000000000000000000000000000000000000000000009093 180.0
HFD2_k127_525811_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K08070 - 1.3.1.74 0.000000000000000000000000000000000009889 148.0
HFD2_k127_525811_2 peptidase m48, ste24p - - - 0.0000000000000000000000000002375 133.0
HFD2_k127_525811_3 PFAM DoxX K16937 - 1.8.5.2 0.0000004555 58.0
HFD2_k127_5266290_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000008513 225.0
HFD2_k127_5266290_1 Domains in Na-Ca exchangers and integrin-beta4 K01406 - 3.4.24.40 0.0000000000000000000000000000000000000000000000007514 201.0
HFD2_k127_5266290_2 HemY domain protein - - - 0.0000000000000000000000000000000003013 153.0
HFD2_k127_5266290_3 Metallo-peptidase family M12B Reprolysin-like - - - 0.000000000000000000000001225 122.0
HFD2_k127_5266290_4 COGs COG4935 Regulatory P domain of the subtilisin-like proprotein convertase and other protease K13735,K20276,K20755,K21449 - 3.4.21.121 0.000000000000000001596 102.0
HFD2_k127_528223_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 307.0
HFD2_k127_528223_1 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002377 271.0
HFD2_k127_528223_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000005477 228.0
HFD2_k127_528223_3 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000001154 112.0
HFD2_k127_528223_4 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.000000000000000000004057 103.0
HFD2_k127_5305616_0 ATPase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 401.0
HFD2_k127_5305616_1 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.00000000000000000000000000000000000000000000000000000000004129 215.0
HFD2_k127_5305616_2 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000007697 114.0
HFD2_k127_530716_0 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000011 276.0
HFD2_k127_5308526_0 Catalyzes the conversion of dihydroorotate to orotate K00226,K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2,1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000003509 261.0
HFD2_k127_5308526_1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00528,K02823 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000006989 233.0
HFD2_k127_5308526_2 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000004731 175.0
HFD2_k127_5312244_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000005506 192.0
HFD2_k127_5312244_1 Sulfate ABC transporter substrate-binding protein K02048 - - 0.000000000000000000000000000000000000000000000002987 186.0
HFD2_k127_5320190_0 Polysaccharide lyase family 4, domain II - - - 0.000000000000000000000000000000000000000000000004776 181.0
HFD2_k127_5320190_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000002386 132.0
HFD2_k127_5320190_2 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000003889 88.0
HFD2_k127_5320190_3 COG COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms Transcription - - - 0.0000000000008255 72.0
HFD2_k127_5330850_0 PFAM Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000001339 239.0
HFD2_k127_5330850_1 coenzyme F390 K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000001187 192.0
HFD2_k127_5330850_2 Peptidase, M23 - - - 0.0000000000000000000000000000000000003239 151.0
HFD2_k127_5330850_3 COG1566 Multidrug resistance efflux pump - - - 0.000000000000000000000000000000009379 142.0
HFD2_k127_5330850_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.0004641 51.0
HFD2_k127_5336095_0 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000004517 235.0
HFD2_k127_5336095_1 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000002457 136.0
HFD2_k127_5336095_2 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000009319 87.0
HFD2_k127_5336095_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0002458 47.0
HFD2_k127_534516_0 Major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 381.0
HFD2_k127_534516_1 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000002043 233.0
HFD2_k127_5355442_0 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 598.0
HFD2_k127_5355442_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005396 258.0
HFD2_k127_5355442_2 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002899 265.0
HFD2_k127_5355442_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000001929 56.0
HFD2_k127_5369930_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000001576 241.0
HFD2_k127_5369930_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000006651 193.0
HFD2_k127_5369930_2 O-methyltransferase - - - 0.0000000000000000000000000000000000000009212 156.0
HFD2_k127_5369930_3 acr, cog1565 - - - 0.00000000000002737 80.0
HFD2_k127_537019_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 431.0
HFD2_k127_537019_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.00000000000000000000000000000000000000000000000000000000005172 231.0
HFD2_k127_537019_2 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000003995 128.0
HFD2_k127_537019_3 outer membrane efflux protein - - - 0.00000000000000000001856 107.0
HFD2_k127_5386657_0 formate dehydrogenase - - - 2.316e-207 657.0
HFD2_k127_5386657_1 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000004122 164.0
HFD2_k127_5394514_0 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 345.0
HFD2_k127_5394514_1 PFAM OmpA MotB domain protein K03640 - - 0.0000000000000000000000000000000000004276 149.0
HFD2_k127_5394514_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000002255 121.0
HFD2_k127_5394514_3 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000004275 70.0
HFD2_k127_5394514_4 TonB C terminal K03832 - - 0.000004795 54.0
HFD2_k127_540122_0 Belongs to the heat shock protein 70 family - - - 1.551e-313 979.0
HFD2_k127_540122_1 Heat shock protein 70 family - - - 5.536e-260 811.0
HFD2_k127_5423558_0 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 295.0
HFD2_k127_5423558_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 296.0
HFD2_k127_5423558_2 P-loop ATPase protein family K06958 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000002093 251.0
HFD2_k127_5457042_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000732 456.0
HFD2_k127_5457042_1 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 379.0
HFD2_k127_5457042_2 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000003124 210.0
HFD2_k127_5457042_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000003731 61.0
HFD2_k127_5457042_4 Cytochrome c554 and c-prime - - - 0.0003054 55.0
HFD2_k127_5480483_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009021 523.0
HFD2_k127_5480483_1 PFAM Outer membrane protein transport protein (OMPP1 FadL TodX) K06076 - - 0.00000000000000000000000000000000000000000000000000000000000001586 231.0
HFD2_k127_5480483_2 peroxiredoxin activity K03564,K07638 - 1.11.1.15,2.7.13.3 0.0000000000000000000000000000000001053 143.0
HFD2_k127_5480483_3 Chalcone isomerase-like - - - 0.00000000000000000000000000000004373 138.0
HFD2_k127_5483620_0 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000155 134.0
HFD2_k127_5497533_0 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000023 142.0
HFD2_k127_5497533_1 TonB-dependent receptor K02014 - - 0.0000000000000000000000002077 119.0
HFD2_k127_5517118_0 PFAM Carbamoyltransferase K00612 - - 2.749e-247 775.0
HFD2_k127_5517779_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 319.0
HFD2_k127_5517779_1 helix_turn_helix, mercury resistance K13640 - - 0.00000000000000000000000000000004069 130.0
HFD2_k127_5523623_0 TIGRFAM competence damage-inducible protein CinA K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000008631 175.0
HFD2_k127_5523623_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000003857 153.0
HFD2_k127_5523623_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000005886 117.0
HFD2_k127_5525404_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000714 525.0
HFD2_k127_5525404_1 AIR synthase related protein, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005306 270.0
HFD2_k127_5525404_2 PFAM Bacterial OB fold (BOF) protein - - - 0.000000000000003276 87.0
HFD2_k127_552578_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 464.0
HFD2_k127_552578_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000007092 253.0
HFD2_k127_552578_2 Penicillin-binding protein, transpeptidase domain protein K03587,K08384 - 3.4.16.4 0.00000000000001264 80.0
HFD2_k127_5526293_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000005534 189.0
HFD2_k127_5526293_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000005456 115.0
HFD2_k127_555016_0 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 442.0
HFD2_k127_555016_1 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000192 215.0
HFD2_k127_555016_2 dUTPase K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000738 184.0
HFD2_k127_555016_3 general secretion pathway protein K02456 - - 0.00000000000000000000000000000000000000000002045 166.0
HFD2_k127_555016_4 type II secretion system protein G K02456 - - 0.0000000000000000000000000000000000009482 143.0
HFD2_k127_555016_5 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000001429 137.0
HFD2_k127_555016_6 general secretion pathway protein K02456,K02650 - - 0.0000000000001385 81.0
HFD2_k127_555016_7 Belongs to the GSP D family K02453 - - 0.000000007641 63.0
HFD2_k127_555016_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K13735 GO:0005575,GO:0005623,GO:0007155,GO:0008150,GO:0009279,GO:0009405,GO:0009987,GO:0016020,GO:0019867,GO:0022610,GO:0030260,GO:0030312,GO:0030313,GO:0031589,GO:0031975,GO:0042710,GO:0043708,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944,GO:0090605 - 0.0002472 52.0
HFD2_k127_555661_0 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 361.0
HFD2_k127_555661_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000003517 158.0
HFD2_k127_555661_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000002407 112.0
HFD2_k127_555661_3 peroxiredoxin activity - - - 0.0000000001249 63.0
HFD2_k127_5559730_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 525.0
HFD2_k127_5559730_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001102 267.0
HFD2_k127_5566176_0 PFAM Cytochrome b b6 domain - - - 1.162e-197 639.0
HFD2_k127_5566176_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000000000000000009183 160.0
HFD2_k127_5566176_2 Cytochrome c K02305 - - 0.000000000000000000000000000000001444 143.0
HFD2_k127_5566176_3 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000000007824 127.0
HFD2_k127_5570322_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 349.0
HFD2_k127_5577719_0 tartrate metabolic process K01676,K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 590.0
HFD2_k127_5577719_1 domain protein - - - 0.000000000000000000000000000000000002701 143.0
HFD2_k127_5577719_2 - - - - 0.0000000000000000000004438 101.0
HFD2_k127_5577719_3 Bacterial protein of unknown function (DUF885) - - - 0.00000000009159 73.0
HFD2_k127_5578957_0 Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 471.0
HFD2_k127_5578957_1 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000001822 162.0
HFD2_k127_5593882_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000004648 225.0
HFD2_k127_5593882_1 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000003292 220.0
HFD2_k127_5593882_2 SMART PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000006033 171.0
HFD2_k127_5601692_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 420.0
HFD2_k127_5601692_1 PFAM peptidase - - - 0.000000000000000000000000000000000001573 152.0
HFD2_k127_5601692_2 extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000678 98.0
HFD2_k127_5604193_0 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - 0.000000000000000000000000000000000000000000000000000000000003697 222.0
HFD2_k127_5604193_1 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000002785 198.0
HFD2_k127_5604193_2 belongs to the thioredoxin family K03671,K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000007697 114.0
HFD2_k127_5612962_0 photosynthesis - - - 0.00000000000000000000000000000000000000000000004791 175.0
HFD2_k127_5612962_1 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000764 93.0
HFD2_k127_5612962_2 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000002804 79.0
HFD2_k127_5625446_0 secretion system protein K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 396.0
HFD2_k127_5625446_1 Belongs to the GSP D family K02280 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001149 296.0
HFD2_k127_5625446_2 Putative Flp pilus-assembly TadE/G-like - - - 0.000000000000000000000000000000000000000000000000000004299 204.0
HFD2_k127_5625446_3 AAA domain K02282 - - 0.000000000000000000000000000000000000000004803 173.0
HFD2_k127_5667719_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066 - 1.1.1.132,1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 427.0
HFD2_k127_5667719_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000002946 122.0
HFD2_k127_5667719_2 COG3307 Lipid A core - O-antigen ligase and related enzymes K02847 - - 0.000000276 63.0
HFD2_k127_5667719_3 GDSL-like Lipase/Acylhydrolase family - - - 0.0000008634 59.0
HFD2_k127_5684849_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 603.0
HFD2_k127_5684849_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00004046 47.0
HFD2_k127_5689056_0 Lanthionine synthetase C-like protein - - - 0.00000000000000000000000000000000000000000000000000000000007527 216.0
HFD2_k127_5689056_1 TIGRFAM type 2 lantibiotic, mersacidin lichenicidin family - - - 0.00001745 50.0
HFD2_k127_5689056_2 TIGRFAM type 2 lantibiotic, mersacidin lichenicidin family - - - 0.00002606 52.0
HFD2_k127_5693405_0 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000005681 111.0
HFD2_k127_5693405_1 capsule polysaccharide biosynthetic process - - - 0.00000000001004 67.0
HFD2_k127_570717_0 GHMP kinases C terminal K07031 - 2.7.1.168 0.000000000000000000000000000000000000000000000000000006823 203.0
HFD2_k127_570717_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000008846 124.0
HFD2_k127_5716717_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000002784 195.0
HFD2_k127_5716717_1 Guanylate kinase homologues. K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000008802 191.0
HFD2_k127_5716717_2 PFAM YicC-like family, N-terminal region - - - 0.000000007043 57.0
HFD2_k127_5742108_0 Malic enzyme, NAD binding domain K00027,K00029,K00625,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 2.519e-220 698.0
HFD2_k127_5742108_1 response to oxidative stress K04063 - - 0.00000000000000000000002467 103.0
HFD2_k127_5749545_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000007507 211.0
HFD2_k127_5749545_1 Heavy-metal-associated domain - - - 0.00005527 51.0
HFD2_k127_5752384_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.887e-258 820.0
HFD2_k127_5757503_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671,K22345 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9,4.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 420.0
HFD2_k127_5757503_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005159 393.0
HFD2_k127_5757503_2 water channel activity K02440,K06188,K09874 - - 0.000000000000000000000000000000000000000000000000000000000000000000007628 247.0
HFD2_k127_5757503_3 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.00000000000000000000000000000000000000000000000000000003205 201.0
HFD2_k127_5757503_4 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000002254 141.0
HFD2_k127_5757503_5 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000744 127.0
HFD2_k127_5757503_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.000000000000000000000000003392 114.0
HFD2_k127_5757503_7 4Fe-4S binding domain K03616 - - 0.00000000000000002149 89.0
HFD2_k127_5757633_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 1.046e-249 797.0
HFD2_k127_5757633_1 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006326 282.0
HFD2_k127_5757633_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000201 177.0
HFD2_k127_5763343_0 AMP binding - - - 0.000000000000000000000000001727 119.0
HFD2_k127_5763343_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000001528 99.0
HFD2_k127_5764487_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000326 278.0
HFD2_k127_5764487_1 PFAM 2Fe-2S -binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.000000000000000000000000000000000000000000000000000000000002771 212.0
HFD2_k127_5767056_0 COG0604 NADPH quinone reductase and related Zn-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006864 258.0
HFD2_k127_5767056_1 protein-glutamate O-methyltransferase activity K00575,K03408,K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000001236 126.0
HFD2_k127_5767056_2 Polysaccharide deacetylase - - - 0.000000000000000000004524 96.0
HFD2_k127_5769341_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 330.0
HFD2_k127_5769341_1 -O-antigen K02847,K13009 - - 0.0000000000000000008597 99.0
HFD2_k127_5778920_0 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 520.0
HFD2_k127_5778920_1 cell redox homeostasis K03671 - - 0.000000000000000216 86.0
HFD2_k127_5778920_2 Belongs to the ompA family K20276 - - 0.00000005821 66.0
HFD2_k127_5786427_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 426.0
HFD2_k127_5786427_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 352.0
HFD2_k127_5786427_2 TIGRFAM methylmalonyl-CoA mutase N-terminal domain K01847,K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000009824 213.0
HFD2_k127_5791280_0 CarboxypepD_reg-like domain - - - 0.0000000000000000000000001317 120.0
HFD2_k127_5791280_1 - - - - 0.0001105 54.0
HFD2_k127_5791280_2 - - - - 0.0006926 49.0
HFD2_k127_5813592_0 Aminotransferase class I and II K00812,K10907,K14287 - 2.6.1.1,2.6.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 348.0
HFD2_k127_5813592_1 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000111 215.0
HFD2_k127_583049_0 Starch synthase catalytic domain K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007271 340.0
HFD2_k127_583049_1 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.00000000000000000000000487 103.0
HFD2_k127_5837199_0 ATPase activity K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 434.0
HFD2_k127_5837199_1 sulfate ABC transporter K02046 - - 0.00000000000000000000000000000000000000000000000004449 188.0
HFD2_k127_5837199_2 PFAM Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000003513 163.0
HFD2_k127_5863824_0 Thiazole biosynthesis protein ThiG K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 374.0
HFD2_k127_5863824_1 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000002087 174.0
HFD2_k127_5863824_2 fatty acid desaturase - - - 0.000000000000003972 87.0
HFD2_k127_5863824_3 ThiS family - - - 0.00000000496 60.0
HFD2_k127_5880235_0 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 312.0
HFD2_k127_5880235_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001483 297.0
HFD2_k127_5880235_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003443 259.0
HFD2_k127_5880235_3 Dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003162 263.0
HFD2_k127_5880235_4 antisigma factor binding K03409,K04749,K07122 - - 0.00008369 49.0
HFD2_k127_5883646_0 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 389.0
HFD2_k127_5883646_1 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000002141 193.0
HFD2_k127_5883646_2 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000718 69.0
HFD2_k127_5884185_0 glycolate biosynthetic process K01091,K06019 - 3.1.3.18,3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000007423 219.0
HFD2_k127_5884185_1 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000001278 101.0
HFD2_k127_5884185_2 sodium-dependent phosphate transmembrane transporter activity - - - 0.0000002636 56.0
HFD2_k127_5884931_0 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 424.0
HFD2_k127_5884931_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000001615 181.0
HFD2_k127_5884931_2 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000000000000001068 170.0
HFD2_k127_5884931_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000001147 169.0
HFD2_k127_5884931_4 - - - - 0.0000197 50.0
HFD2_k127_5886520_0 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000008335 234.0
HFD2_k127_5886520_1 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000001733 179.0
HFD2_k127_5886520_2 methionine synthase K00548 - 2.1.1.13 0.000000000000000273 85.0
HFD2_k127_5894488_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000001265 156.0
HFD2_k127_5894488_1 - - - - 0.000000000005241 76.0
HFD2_k127_5900700_0 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008121 548.0
HFD2_k127_5900700_1 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 445.0
HFD2_k127_5905916_0 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 404.0
HFD2_k127_5909890_0 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 580.0
HFD2_k127_5909890_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000006809 154.0
HFD2_k127_5911409_0 AMMECR1 K09141 - - 0.00000000000000000000000000000000000000000003447 167.0
HFD2_k127_5911409_1 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000001714 74.0
HFD2_k127_5911409_2 Lysin motif - - - 0.0000002846 61.0
HFD2_k127_5911409_3 PFAM helix-turn-helix, Fis-type - - - 0.000001034 60.0
HFD2_k127_5917473_0 Tryptophan 2,3-dioxygenase K00453 - 1.13.11.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008045 345.0
HFD2_k127_5917473_1 Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid K00486 - 1.14.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 306.0
HFD2_k127_5917473_2 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.0001242 44.0
HFD2_k127_5932720_0 iron-sulfur cluster assembly K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006075 567.0
HFD2_k127_5932720_1 protein tyrosine kinase activity K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 366.0
HFD2_k127_5932720_2 transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000000000000000000009978 153.0
HFD2_k127_5932720_3 bacterial OsmY and nodulation domain K04065 GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 - 0.0000000000000000005581 94.0
HFD2_k127_5932720_4 translation initiation factor activity K03699 - - 0.0000000000000002524 87.0
HFD2_k127_5932720_5 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0002601 51.0
HFD2_k127_5934145_0 Type II secretion system K12510 - - 0.00000000000000000000000000000000000000000000000000000000001064 218.0
HFD2_k127_5934145_1 PFAM type II secretion system protein E K02283 - - 0.0000000000000000000000000000006329 124.0
HFD2_k127_5934145_2 type II secretion system K12511 - - 0.0000000000000000000007301 103.0
HFD2_k127_5935790_0 Nickel-dependent hydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 434.0
HFD2_k127_5935790_1 Coenzyme F420-reducing hydrogenase, gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 355.0
HFD2_k127_5938618_0 palmitoyl-(protein) hydrolase activity K06999 - - 0.00000000000000000000000000000000002363 153.0
HFD2_k127_5938618_1 OsmC-like protein K04063 - - 0.0000000000001084 72.0
HFD2_k127_5944034_0 Glycosyl transferases group 1 K20922 - - 0.000000000000000000000000000000000001748 159.0
HFD2_k127_5944034_1 Pfam Glycosyl transferase family 2 - - - 0.000000000000000000000002583 120.0
HFD2_k127_5944034_2 Glycosyl transferases group 1 - - - 0.00000000000003595 82.0
HFD2_k127_5944034_3 - - - - 0.00000000000006467 72.0
HFD2_k127_5945008_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 314.0
HFD2_k127_5952728_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009654 303.0
HFD2_k127_5952728_1 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003521 281.0
HFD2_k127_5952728_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000004377 248.0
HFD2_k127_5989166_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 3.456e-220 698.0
HFD2_k127_5989166_1 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000249 155.0
HFD2_k127_5989166_2 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000002236 100.0
HFD2_k127_5995065_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 346.0
HFD2_k127_5995065_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 314.0
HFD2_k127_5995065_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000006028 89.0
HFD2_k127_5995065_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000005491 68.0
HFD2_k127_5995065_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.000004427 54.0
HFD2_k127_5995232_0 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005828 273.0
HFD2_k127_5995232_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356,K03503 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000001163 227.0
HFD2_k127_5995232_2 impB/mucB/samB family K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000003536 232.0
HFD2_k127_5995232_3 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000001891 196.0
HFD2_k127_5995232_4 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.00000000000000000000000000000000000000005864 154.0
HFD2_k127_5995232_5 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.0000000000000000000000000000000000000008062 157.0
HFD2_k127_5995232_6 Domain of unknown function (DUF4440) - - - 0.000000000000000000004947 100.0
HFD2_k127_5999022_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 287.0
HFD2_k127_5999022_1 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003641 263.0
HFD2_k127_5999022_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000001671 252.0
HFD2_k127_5999022_3 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.000000000000000000000000000000000000000000003523 177.0
HFD2_k127_5999022_4 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000001567 113.0
HFD2_k127_5999022_5 methyltransferase activity - - - 0.00000000000000005954 94.0
HFD2_k127_5999022_6 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K14441 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 0.00000004314 55.0
HFD2_k127_5999545_0 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 0.00000000000000000000000000000000000000000000000000001068 195.0
HFD2_k127_5999545_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000000000000000000000002243 140.0
HFD2_k127_6004250_0 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 523.0
HFD2_k127_6004250_1 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 305.0
HFD2_k127_6004250_2 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000007558 273.0
HFD2_k127_6004250_3 Alcohol dehydrogenase GroES-like domain K07538 - 1.1.1.368 0.00000000000000000000000000000000000000000000000000000000000000000000000004521 263.0
HFD2_k127_6004250_4 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000004188 125.0
HFD2_k127_6007513_0 Domain of unknown function (DUF5117) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 312.0
HFD2_k127_6008067_0 Glycosyl hydrolase family 63 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 395.0
HFD2_k127_6008067_1 Major intrinsic protein K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004235 275.0
HFD2_k127_6008067_2 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000001236 240.0
HFD2_k127_6024468_0 SurA N-terminal domain K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000006128 245.0
HFD2_k127_6024468_1 Putative metal-binding motif - - - 0.0000000000000000000000000000000008191 147.0
HFD2_k127_6024468_2 Tetratricopeptide repeat - - - 0.000000000000000004604 91.0
HFD2_k127_6025029_0 DNA polymerase III, delta' K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000402 171.0
HFD2_k127_6025029_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000129 73.0
HFD2_k127_6025029_2 ABC transporter transmembrane region K06147,K18889 - - 0.000003768 55.0
HFD2_k127_6028806_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 515.0
HFD2_k127_6028806_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006028 474.0
HFD2_k127_6028806_10 Glycosyltransferase Family 4 - - - 0.00000001536 63.0
HFD2_k127_6028806_11 Methyltransferase - - - 0.0006036 50.0
HFD2_k127_6028806_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009425 437.0
HFD2_k127_6028806_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 435.0
HFD2_k127_6028806_4 COGs COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 319.0
HFD2_k127_6028806_5 glycosyl transferase family 39 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000004318 213.0
HFD2_k127_6028806_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000003921 191.0
HFD2_k127_6028806_7 Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway K03525 - 2.7.1.33 0.0000000000000000000000000000008368 137.0
HFD2_k127_6028806_8 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000002133 132.0
HFD2_k127_6028806_9 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000002115 112.0
HFD2_k127_6034716_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 5.353e-224 707.0
HFD2_k127_6050505_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 468.0
HFD2_k127_6050505_1 Threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 375.0
HFD2_k127_6050505_2 TIGRFAM LAO AO transport system ATPase K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009896 298.0
HFD2_k127_6050505_3 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000007897 219.0
HFD2_k127_6060110_0 breast cancer carboxy-terminal domain K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 4.438e-197 636.0
HFD2_k127_6060110_1 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 494.0
HFD2_k127_6060110_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 427.0
HFD2_k127_6060110_3 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 424.0
HFD2_k127_6060110_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 351.0
HFD2_k127_6060110_5 Histidine kinase - - - 0.000000000000000000000000000000000000000006958 172.0
HFD2_k127_6060110_6 3-hydroxyacyl-CoA dehydrogenase K00074,K01782 - 1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000009846 175.0
HFD2_k127_6060110_7 Chemotaxis protein CheY K02490 - - 0.00000000000000000001676 101.0
HFD2_k127_6060110_8 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00006177 53.0
HFD2_k127_6063505_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 432.0
HFD2_k127_6063505_1 Endoribonuclease that initiates mRNA decay K18682 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 333.0
HFD2_k127_6063505_2 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000001554 223.0
HFD2_k127_6063505_3 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000002118 122.0
HFD2_k127_6066450_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 4.382e-222 698.0
HFD2_k127_6066450_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 471.0
HFD2_k127_6066450_2 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 334.0
HFD2_k127_6066450_3 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000004275 229.0
HFD2_k127_6075134_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.171e-263 822.0
HFD2_k127_6075134_1 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 413.0
HFD2_k127_6075134_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000001192 206.0
HFD2_k127_6075134_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000004048 180.0
HFD2_k127_6075134_4 cyclohydrolase K01746 - 4.3.1.4 0.0000000000000000000000000000000000009013 147.0
HFD2_k127_6075134_5 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000002966 131.0
HFD2_k127_6075134_6 tRNA (adenine(22)-N(1))-methyltransferase K06967 - 2.1.1.217 0.00000000000000000000000000005874 123.0
HFD2_k127_6075134_7 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000005982 111.0
HFD2_k127_6075134_8 DivIVA protein K04074 - - 0.0000000000000000000003582 109.0
HFD2_k127_6075858_0 TIGRFAM aminoacyl-histidine dipeptidase K01270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 566.0
HFD2_k127_6075858_1 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009353 566.0
HFD2_k127_6075858_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000004518 160.0
HFD2_k127_6075858_3 Belongs to the UPF0761 family K07058 - - 0.000000000000000000000151 108.0
HFD2_k127_6075858_4 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000003071 108.0
HFD2_k127_6075858_5 Zinc metalloprotease (Elastase) K09607 - - 0.000000000000005632 89.0
HFD2_k127_6075858_6 ubiE/COQ5 methyltransferase family - - - 0.00000000000005216 82.0
HFD2_k127_6075858_7 Putative metal-binding motif - - - 0.000000008282 68.0
HFD2_k127_6080670_0 Involved in the tonB-independent uptake of proteins K01256,K03641 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 419.0
HFD2_k127_6089118_0 Methionine synthase K00548 - 2.1.1.13 1.749e-212 670.0
HFD2_k127_6101154_1 Protein of unknown function (DUF3570) - - - 0.0000000000000000000000000000000002171 147.0
HFD2_k127_6101154_2 Thioredoxin-like - - - 0.00000000000000000000000183 113.0
HFD2_k127_6109648_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 450.0
HFD2_k127_6109648_1 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000004118 214.0
HFD2_k127_6118682_0 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 356.0
HFD2_k127_6122090_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.016e-273 853.0
HFD2_k127_6122090_1 Protein export membrane protein K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009942 276.0
HFD2_k127_6122090_2 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000877 218.0
HFD2_k127_6122090_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000003862 135.0
HFD2_k127_6122090_4 Family 5 K02035,K15580 - - 0.00000000000000000000002654 118.0
HFD2_k127_6125271_0 Belongs to the UPF0173 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004437 259.0
HFD2_k127_6125271_1 Receptor - - - 0.0000005465 61.0
HFD2_k127_6133936_0 cheY-homologous receiver domain K07668 - - 0.000000000000000000000000000007146 123.0
HFD2_k127_6133936_1 PFAM EAL domain - - - 0.000000000000000000000000155 118.0
HFD2_k127_6133936_2 PilZ domain - - - 0.00008969 51.0
HFD2_k127_6137120_0 Dimerisation domain of Zinc Transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 381.0
HFD2_k127_6137120_1 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000241 126.0
HFD2_k127_6137246_0 cell shape determining protein MreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 330.0
HFD2_k127_6137246_1 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000007586 229.0
HFD2_k127_6137246_2 rod shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000002896 155.0
HFD2_k127_6137246_3 Rod shape-determining protein K03571 - - 0.00001535 53.0
HFD2_k127_6138485_0 MviN-like protein K03980 - - 0.000000000000000000000000000000000000000002386 169.0
HFD2_k127_6138485_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000001564 115.0
HFD2_k127_61479_0 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 587.0
HFD2_k127_61479_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004813 306.0
HFD2_k127_61479_2 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002823 281.0
HFD2_k127_6148736_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000007735 176.0
HFD2_k127_6165003_0 LytB protein K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005485 383.0
HFD2_k127_6166195_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 378.0
HFD2_k127_6166195_1 Type II secretion system (T2SS), protein F K12511 - - 0.0000000000000000000003612 110.0
HFD2_k127_6166195_2 Periplasmic or secreted lipoprotein - - - 0.0000000000004347 78.0
HFD2_k127_6166195_3 Alginate export - - - 0.00000000008586 74.0
HFD2_k127_617350_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000007686 159.0
HFD2_k127_617350_1 Conserved Protein - - - 0.0000000000000000000000000000000000003489 154.0
HFD2_k127_617350_2 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000005842 143.0
HFD2_k127_617350_3 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.000000000000008843 80.0
HFD2_k127_6179927_0 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005681 612.0
HFD2_k127_6179927_1 Belongs to the peptidase S8 family K01400,K01417,K20274 - 3.4.24.28 0.0000000000000000000000000000000000000000000001783 194.0
HFD2_k127_6195222_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008875 512.0
HFD2_k127_6195222_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000005934 263.0
HFD2_k127_6197275_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1079.0
HFD2_k127_6197275_1 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 452.0
HFD2_k127_6197275_2 phosphorelay sensor kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002089 247.0
HFD2_k127_6197275_3 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000006247 200.0
HFD2_k127_6197275_4 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000001786 188.0
HFD2_k127_6197275_5 COG NOG19114 non supervised orthologous group - - - 0.000402 50.0
HFD2_k127_6225715_0 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000001929 208.0
HFD2_k127_6225715_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K08070 - 1.3.1.74 0.00000000000000000000000000000000000000000000000000000008012 199.0
HFD2_k127_6225715_2 Domain of unknown function (DUF4198) - - - 0.0005739 51.0
HFD2_k127_6230089_0 PFAM Iron permease FTR1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000964 311.0
HFD2_k127_6230089_1 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000006365 133.0
HFD2_k127_6230089_2 Efflux ABC transporter, permease protein K02004 - - 0.00000000000000000000001106 110.0
HFD2_k127_6230089_3 Transcriptional regulator, DeoR family K21601 - - 0.00003948 52.0
HFD2_k127_6231834_0 - K12065 - - 0.000000000000000000000000000000000000000000000000000000000000000001903 237.0
HFD2_k127_6231834_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000001229 144.0
HFD2_k127_6251997_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 513.0
HFD2_k127_6251997_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 331.0
HFD2_k127_6262242_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016151,GO:0016491,GO:0022900,GO:0030288,GO:0030313,GO:0031975,GO:0032991,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0044569,GO:0045333,GO:0046872,GO:0046914,GO:0055114,GO:0071944,GO:1902494 1.12.99.6 3.469e-227 708.0
HFD2_k127_6262242_1 COGs COG1740 Ni Fe-hydrogenase I small subunit K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 395.0
HFD2_k127_6275505_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 1.977e-256 804.0
HFD2_k127_6275505_1 COGs COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000008225 218.0
HFD2_k127_6275505_2 PFAM CBS domain containing protein - - - 0.0000000000000001366 85.0
HFD2_k127_6278367_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 523.0
HFD2_k127_6278367_1 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000009294 58.0
HFD2_k127_6289666_0 radical SAM domain protein K22318 - - 9.57e-224 725.0
HFD2_k127_6289666_1 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000005017 198.0
HFD2_k127_6289666_2 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000005503 112.0
HFD2_k127_6293454_0 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000002897 267.0
HFD2_k127_6293454_1 SIS domain K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000002678 181.0
HFD2_k127_6293454_2 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.00000000000000000000000000000000000000001455 161.0
HFD2_k127_6293454_3 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000002503 150.0
HFD2_k127_6293454_4 Belongs to the SIS family. GutQ KpsF subfamily K01627,K03281,K06041 - 2.5.1.55,5.3.1.13 0.000000000000000000000000000000007798 136.0
HFD2_k127_6293454_5 Belongs to the UPF0434 family K09791 - - 0.000000000001898 68.0
HFD2_k127_6293454_6 Tetratricopeptide repeat - - - 0.000002457 59.0
HFD2_k127_6293454_7 GDSL-like Lipase/Acylhydrolase family - - - 0.000004477 59.0
HFD2_k127_6315011_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 432.0
HFD2_k127_6315011_1 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000000002832 143.0
HFD2_k127_6315011_2 Regulatory protein - - - 0.0000000000000000000000001023 112.0
HFD2_k127_6315011_3 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000001115 84.0
HFD2_k127_6320931_0 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000135 185.0
HFD2_k127_6320931_1 PFAM Glycosyl transferase, group 1 K19424 - - 0.00000000000000000000001735 109.0
HFD2_k127_6320931_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000002398 86.0
HFD2_k127_6322953_0 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 444.0
HFD2_k127_6322953_1 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761,K17217 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.2,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 396.0
HFD2_k127_6322953_2 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 325.0
HFD2_k127_6322953_3 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009732 321.0
HFD2_k127_6322953_4 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000446 238.0
HFD2_k127_6322953_5 Peptidase, S41 K03797 - 3.4.21.102 0.00000000000000000000215 111.0
HFD2_k127_6322953_6 Histidine kinase K11383 - 2.7.13.3 0.00000001642 67.0
HFD2_k127_6329568_0 AAA ATPase, central domain protein K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 372.0
HFD2_k127_6329568_1 Glycosyl transferase family group 2 K00752,K11936 - 2.4.1.212 0.00000000000000000000000000000000000000000000000000000000000282 215.0
HFD2_k127_6329568_2 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000000000000000002116 175.0
HFD2_k127_6329568_3 Putative zinc-finger - - - 0.0000000000005724 75.0
HFD2_k127_6330896_0 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 407.0
HFD2_k127_6330896_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000008941 58.0
HFD2_k127_6339404_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000024 245.0
HFD2_k127_6339404_1 formate dehydrogenase K00127 - - 0.00000000000000000000014 109.0
HFD2_k127_6339404_2 ABC transporter K06158 - - 0.0006171 45.0
HFD2_k127_6343320_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009953 298.0
HFD2_k127_6343320_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000117 273.0
HFD2_k127_6343320_2 ATP synthesis coupled proton transport K02109 - - 0.0000000000000000000000000001232 121.0
HFD2_k127_6343320_3 ATP hydrolysis coupled proton transport K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000344 92.0
HFD2_k127_6343320_4 Acetyltransferase (GNAT) domain - - - 0.000000004475 63.0
HFD2_k127_6343320_5 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.0008502 50.0
HFD2_k127_6347015_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000811 500.0
HFD2_k127_6347015_1 CarboxypepD_reg-like domain - - - 0.00000000000000002618 97.0
HFD2_k127_6377015_0 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006608 298.0
HFD2_k127_6377015_1 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.0000000000000000000000000000000003627 138.0
HFD2_k127_6385839_0 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002786 273.0
HFD2_k127_6385839_1 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000001291 230.0
HFD2_k127_6385839_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000003549 122.0
HFD2_k127_6385839_3 Biotin-requiring enzyme - - - 0.000000000000000000000902 106.0
HFD2_k127_6386175_0 DEAD DEAH box helicase K06877 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 469.0
HFD2_k127_6386175_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008076 463.0
HFD2_k127_6386175_2 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 387.0
HFD2_k127_6399658_0 PFAM NAD-dependent epimerase dehydratase - - - 9.122e-202 645.0
HFD2_k127_6399658_1 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 577.0
HFD2_k127_6399658_2 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 392.0
HFD2_k127_6399658_3 protein-(glutamine-N5) methyltransferase activity - - - 0.0000000000000000000000000000909 127.0
HFD2_k127_6399658_4 redox protein regulator of disulfide bond formation K04063 - - 0.00000000000000000000000001442 111.0
HFD2_k127_6399658_5 ThiF family K21029,K21147 - 2.7.7.80,2.8.1.11 0.0000000000216 74.0
HFD2_k127_642572_0 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003768 255.0
HFD2_k127_642572_1 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000239 259.0
HFD2_k127_642572_2 HYR domain - - - 0.00000000000000000000000000000003266 147.0
HFD2_k127_642572_3 FAD dependent oxidoreductase K00301 - 1.5.3.1 0.00000001553 57.0
HFD2_k127_642572_4 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.0000002703 55.0
HFD2_k127_6442730_0 Predicted membrane protein (DUF2157) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003977 253.0
HFD2_k127_6442730_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000006575 154.0
HFD2_k127_6442730_2 Predicted membrane protein (DUF2157) - - - 0.00000000000000000001185 108.0
HFD2_k127_6442730_3 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit K01426 - 3.5.1.4 0.0000004544 55.0
HFD2_k127_6453008_0 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 324.0
HFD2_k127_6455844_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1188.0
HFD2_k127_6455844_1 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 499.0
HFD2_k127_6457616_0 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009864 295.0
HFD2_k127_6457616_1 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000001378 147.0
HFD2_k127_6457616_2 Lipocalin-like domain - - - 0.00000000000000000000000000003549 119.0
HFD2_k127_6457616_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000003144 63.0
HFD2_k127_6465368_0 Tetratricopeptide repeat - - - 0.0000000000103 71.0
HFD2_k127_6466476_0 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000001089 243.0
HFD2_k127_6466476_1 cell shape determining protein MreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000001125 213.0
HFD2_k127_6466476_2 FecR protein - - - 0.0009778 51.0
HFD2_k127_6471864_0 cellulose binding - - - 1.212e-222 693.0
HFD2_k127_6471864_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 432.0
HFD2_k127_6471864_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 415.0
HFD2_k127_6471864_3 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 394.0
HFD2_k127_6471864_4 Mo-molybdopterin cofactor metabolic process K03636,K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000008503 154.0
HFD2_k127_6476331_0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006558 355.0
HFD2_k127_6476331_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000003874 224.0
HFD2_k127_6503441_0 Permease YjgP YjgQ family protein K07091,K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003214 287.0
HFD2_k127_651757_0 Beta-eliminating lyase K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 311.0
HFD2_k127_651757_1 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000001095 155.0
HFD2_k127_6522273_0 ABC transporter transmembrane region K06147,K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 359.0
HFD2_k127_6522273_1 ABC transporter transmembrane region K06147,K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001469 264.0
HFD2_k127_6527803_0 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.0000000000000000000000000000000000000000005807 167.0
HFD2_k127_6527803_1 aminotransferase K00817 - 2.6.1.9 0.000000000000000000000000000000005507 134.0
HFD2_k127_6536574_0 UDP binding domain K02474,K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 559.0
HFD2_k127_6536574_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008843 561.0
HFD2_k127_6536574_2 Hydantoinaseoxoprolinase domain protein K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 458.0
HFD2_k127_6536574_3 Male sterility protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008552 375.0
HFD2_k127_6536574_4 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006276 264.0
HFD2_k127_6536574_5 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000002223 229.0
HFD2_k127_6536574_6 MlaD protein K02067 - - 0.000000000000000000000000000000000007003 151.0
HFD2_k127_6536574_7 Hydantoinaseoxoprolinase domain protein K01473 - 3.5.2.14 0.0000000000000000000001149 102.0
HFD2_k127_6536574_8 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000114 93.0
HFD2_k127_6537701_0 - - - - 0.000000000004491 79.0
HFD2_k127_6537701_1 - - - - 0.00005329 50.0
HFD2_k127_6538939_0 PFAM Type II secretion system protein E K02454,K02652 - - 0.00000000000000000000000000000000000000000002913 182.0
HFD2_k127_6538939_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000005162 133.0
HFD2_k127_6540867_0 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 490.0
HFD2_k127_6543838_0 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 463.0
HFD2_k127_6543838_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000001966 127.0
HFD2_k127_6543838_2 Putative zinc-finger - - - 0.000004657 58.0
HFD2_k127_6547047_0 Domain of unknown function DUF11 - - - 0.00000000000000000000000000000000007046 151.0
HFD2_k127_6552383_0 - - - - 0.00000000000000000000002146 106.0
HFD2_k127_6552383_1 Outer membrane receptor K02014,K16087 - - 0.000000000000005286 85.0
HFD2_k127_6577771_0 UDP-N-acetylmuramate-L-alanine ligase activity K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 374.0
HFD2_k127_6577771_1 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 330.0
HFD2_k127_6577771_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 306.0
HFD2_k127_6577771_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000005201 95.0
HFD2_k127_657842_0 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009315 486.0
HFD2_k127_657842_1 Malate synthase K01638 - 2.3.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000575 250.0
HFD2_k127_658156_0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 310.0
HFD2_k127_658156_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001881 258.0
HFD2_k127_658156_10 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000009124 75.0
HFD2_k127_658156_11 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000000342 71.0
HFD2_k127_658156_2 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000002738 232.0
HFD2_k127_658156_3 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000175 179.0
HFD2_k127_658156_4 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000002286 183.0
HFD2_k127_658156_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000001838 160.0
HFD2_k127_658156_6 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000004418 133.0
HFD2_k127_658156_7 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000002468 121.0
HFD2_k127_658156_8 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000008789 107.0
HFD2_k127_658156_9 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000002374 101.0
HFD2_k127_6587815_0 homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 383.0
HFD2_k127_6587815_1 Protein tyrosine kinase - - - 0.000000001255 70.0
HFD2_k127_659034_0 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 329.0
HFD2_k127_659034_1 Uncharacterized ACR, COG1993 K06199,K09137 - - 0.000000000000000000000000000000000000000000000000000001944 193.0
HFD2_k127_659034_2 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000001952 192.0
HFD2_k127_659034_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000000000000000002246 138.0
HFD2_k127_659034_5 - - - - 0.000001948 51.0
HFD2_k127_6590938_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 350.0
HFD2_k127_6590938_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000006799 210.0
HFD2_k127_6595404_0 acyl-CoA dehydrogenase activity K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 509.0
HFD2_k127_6595404_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 444.0
HFD2_k127_6595404_2 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000009722 219.0
HFD2_k127_6595404_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000006447 196.0
HFD2_k127_6595404_4 PFAM SNARE associated Golgi protein K03975 - - 0.0009868 47.0
HFD2_k127_6598143_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.000000000000000000000000000000000000000000000001004 195.0
HFD2_k127_6598143_1 CarD-like/TRCF domain K07736 - - 0.000000000000000000000000000000000000904 145.0
HFD2_k127_6598143_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000684 57.0
HFD2_k127_6598616_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 568.0
HFD2_k127_6598616_1 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000009014 194.0
HFD2_k127_6598616_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000001379 80.0
HFD2_k127_6628686_0 AcrB/AcrD/AcrF family K03296 - - 2.403e-288 901.0
HFD2_k127_6628686_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 313.0
HFD2_k127_6628686_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000008741 117.0
HFD2_k127_6635468_0 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 542.0
HFD2_k127_6635468_1 succinyl-diaminopimelate desuccinylase activity K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 502.0
HFD2_k127_6635468_2 PFAM Aldo keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001839 267.0
HFD2_k127_6635468_3 Sortase and related acyltransferases K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000000001443 228.0
HFD2_k127_6635468_4 PFAM MOSC domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000001143 214.0
HFD2_k127_6635468_5 Sugar fermentation stimulation protein K06206 - - 0.0000000000000000000000000000000000000007236 159.0
HFD2_k127_6635468_6 Competence protein TfoX K07343 - - 0.00000000000000002931 86.0
HFD2_k127_6635468_7 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000338 64.0
HFD2_k127_6635468_8 O-linked N-acetylglucosamine transferase, SPINDLY family - - - 0.00006779 55.0
HFD2_k127_6652073_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 449.0
HFD2_k127_6652073_1 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000005333 262.0
HFD2_k127_6652073_2 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000006953 213.0
HFD2_k127_6652073_3 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000004098 147.0
HFD2_k127_6652983_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 550.0
HFD2_k127_6652983_1 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 529.0
HFD2_k127_6652983_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000009038 227.0
HFD2_k127_6652983_3 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000005219 138.0
HFD2_k127_6662790_0 Protein of unknown function, DUF255 K06888 - - 1.044e-251 797.0
HFD2_k127_6662790_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 450.0
HFD2_k127_6662790_2 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000008882 271.0
HFD2_k127_6662790_3 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000004593 205.0
HFD2_k127_6662790_4 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000239 179.0
HFD2_k127_6662790_5 Protein of unknown function, DUF547 - - - 0.0000000000000000000000000000000000000007714 163.0
HFD2_k127_6662790_6 peroxiredoxin activity - - - 0.0000000000000000000000000000000000002192 148.0
HFD2_k127_6688867_0 PFAM chalcone and stilbene synthase domain protein K16167 - - 0.000000000000000000000000000000000000000000000000000000000000000005047 241.0
HFD2_k127_6688867_1 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000001726 135.0
HFD2_k127_6688867_2 Oxidoreductase - - - 0.00000000000000000000000011 113.0
HFD2_k127_6694406_0 Conserved hypothetical protein (DUF2461) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 307.0
HFD2_k127_6694406_1 spore germination K03605 - - 0.0000000000000000000000000002339 123.0
HFD2_k127_6694406_2 GIY-YIG catalytic domain K07461 - - 0.00000000000000002932 94.0
HFD2_k127_6694406_3 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.0000000000000005018 78.0
HFD2_k127_6710726_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.077e-222 700.0
HFD2_k127_6715611_0 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001136 265.0
HFD2_k127_6717736_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 6.385e-214 674.0
HFD2_k127_6717736_1 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 609.0
HFD2_k127_6718382_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000019 115.0
HFD2_k127_6718382_1 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000002402 90.0
HFD2_k127_6738188_0 Male sterility protein K01710,K01784 - 4.2.1.46,5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 336.0
HFD2_k127_6738188_1 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003374 251.0
HFD2_k127_6738188_2 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.000001053 54.0
HFD2_k127_674020_0 Conserved protein of dim6 ntab family - - - 0.00000000000000000000000000000000000000000000000004279 193.0
HFD2_k127_674020_1 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000007187 149.0
HFD2_k127_674020_2 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000002039 139.0
HFD2_k127_674020_3 lyase activity - - - 0.0000000000000000000000000000009478 135.0
HFD2_k127_674020_4 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000000000005547 123.0
HFD2_k127_674020_5 Ferredoxin - - - 0.000000000000000000003625 99.0
HFD2_k127_6743874_0 Two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000001244 234.0
HFD2_k127_6743874_1 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000006919 173.0
HFD2_k127_676545_0 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006051 378.0
HFD2_k127_676545_1 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008376 330.0
HFD2_k127_6776144_0 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 458.0
HFD2_k127_6776144_1 Dodecin K09165 - - 0.00000000000000000000000003786 112.0
HFD2_k127_678908_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 416.0
HFD2_k127_678908_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000006252 138.0
HFD2_k127_678908_2 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000006034 132.0
HFD2_k127_6801713_0 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000007429 200.0
HFD2_k127_6805934_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 505.0
HFD2_k127_6805934_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 430.0
HFD2_k127_6805934_2 2 iron, 2 sulfur cluster binding K00334,K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000001148 174.0
HFD2_k127_682035_0 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 353.0
HFD2_k127_682035_1 PFAM ABC transporter related K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 286.0
HFD2_k127_6824923_0 Glycosyl hydrolase family 57 - - - 0.0000000000000000000000000000000000514 146.0
HFD2_k127_6828052_0 peptidylprolyl isomerase, FKBP-type K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000186 231.0
HFD2_k127_6828052_1 methyltransferase - - - 0.000000000000009594 83.0
HFD2_k127_6828130_0 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000005833 247.0
HFD2_k127_6828130_1 TonB-dependent Receptor Plug Domain K02014 - - 0.00000000000000000000000000000001971 129.0
HFD2_k127_6835714_0 PFAM SAF domain K02279 - - 0.0000000000000000000000000000000000000000000000000005486 194.0
HFD2_k127_6835714_1 Type IV leader peptidase family K02278 - 3.4.23.43 0.0000000000000000000001871 106.0
HFD2_k127_6835714_2 TadE-like protein - - - 0.000001492 58.0
HFD2_k127_6835714_3 PFAM Flp Fap pilin component K02651 - - 0.000001654 57.0
HFD2_k127_6835714_4 PFAM Flp Fap pilin component K02651 - - 0.0002209 47.0
HFD2_k127_6841287_0 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 296.0
HFD2_k127_6841287_1 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 291.0
HFD2_k127_6843153_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 589.0
HFD2_k127_6843153_1 proline dipeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002701 250.0
HFD2_k127_6843153_2 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.0000000000000000000000000000000000000000000000000003183 196.0
HFD2_k127_6843442_0 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001124 268.0
HFD2_k127_6843442_1 UvrD REP helicase K16898 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000002362 230.0
HFD2_k127_6848631_0 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 489.0
HFD2_k127_6848631_1 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007571 466.0
HFD2_k127_6848631_2 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 - 1.13.11.6 0.0000000000000000000000000000000000000000000002281 169.0
HFD2_k127_6848631_3 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K00486 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0016491,GO:0019748,GO:0044550,GO:0055114 1.14.13.9 0.0000000000000000000000000000000000000000491 158.0
HFD2_k127_6858012_0 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 400.0
HFD2_k127_6858012_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 361.0
HFD2_k127_6858012_2 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008019 271.0
HFD2_k127_6858012_3 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000001216 237.0
HFD2_k127_6858012_4 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000004183 242.0
HFD2_k127_6858012_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000001658 158.0
HFD2_k127_6858012_6 Arsenical pump membrane protein - - - 0.000000000000000000000000000000000000000008977 163.0
HFD2_k127_6859006_0 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 288.0
HFD2_k127_6859006_1 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.00000000001151 68.0
HFD2_k127_6859006_2 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.00000000001817 71.0
HFD2_k127_6877905_0 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000003093 237.0
HFD2_k127_6877905_1 - - - - 0.00000000000000000000000000000007593 138.0
HFD2_k127_6877905_2 Domain of unknown function (DUF4115) - - - 0.0000000000000000004809 97.0
HFD2_k127_6877905_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000003527 85.0
HFD2_k127_6877905_4 PFAM Tetratricopeptide repeat - - - 0.0000000444 64.0
HFD2_k127_6883927_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007471 426.0
HFD2_k127_6883927_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000009022 66.0
HFD2_k127_6883927_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000008369 57.0
HFD2_k127_6884451_0 4Fe-4S single cluster domain K06937 - - 1.862e-239 757.0
HFD2_k127_6884451_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000003118 195.0
HFD2_k127_6892993_0 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 381.0
HFD2_k127_6892993_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 346.0
HFD2_k127_6893957_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009727 285.0
HFD2_k127_6893957_1 Transport permease protein K01992 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015562,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0033554,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071944 - 0.000000000000000000000000001857 113.0
HFD2_k127_6893957_2 Protein of unknown function (DUF1189) - - - 0.0000000000000000000005013 106.0
HFD2_k127_6910229_0 Seven times multi-haem cytochrome CxxCH K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 2.029e-198 623.0
HFD2_k127_6910229_1 Fe-S oxidoreductases K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 356.0
HFD2_k127_6910229_2 Domain of unknown function (DUF1858) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 334.0
HFD2_k127_6910229_3 Alginate export - - - 0.00000000000000000000000000000000000000000001925 184.0
HFD2_k127_6910229_4 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000000000000003835 149.0
HFD2_k127_6910229_5 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.00000000000000000000000000000001447 136.0
HFD2_k127_6910851_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 530.0
HFD2_k127_6911702_0 elongation factor Tu domain 2 protein K02355 - - 1.172e-244 774.0
HFD2_k127_6911702_1 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.00000000000000000000000000001137 123.0
HFD2_k127_6919018_0 YqeY-like protein K09117 - - 0.00000000000000000000000001744 115.0
HFD2_k127_6921721_0 PFAM transposase IS116 IS110 IS902 family - - - 0.0000000000000000000000000000000000000009735 166.0
HFD2_k127_6921721_1 glyoxalase III activity - - - 0.00000000007678 66.0
HFD2_k127_6929331_0 Histidine kinase - - - 0.00000000000000000000000003231 124.0
HFD2_k127_6945394_0 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009641 308.0
HFD2_k127_6945394_1 UvrD REP helicase K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 315.0
HFD2_k127_6945394_2 Belongs to the peptidase S11 family K07262 GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016043,GO:0016787,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0030203,GO:0032505,GO:0042221,GO:0042493,GO:0042597,GO:0043093,GO:0043170,GO:0044238,GO:0044464,GO:0045229,GO:0050896,GO:0051301,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 - 0.000000000000000000000000000000000000000000000000000005965 194.0
HFD2_k127_6945394_3 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000006862 183.0
HFD2_k127_6971290_0 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000001103 173.0
HFD2_k127_6971290_1 diguanylate cyclase - - - 0.0000000000000000000000000000000004361 147.0
HFD2_k127_6978346_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 392.0
HFD2_k127_6978346_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000001122 145.0
HFD2_k127_6979452_0 Dehydrogenase E1 component K11381 - 1.2.4.4 1.48e-277 869.0
HFD2_k127_6979452_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K02014 - - 0.00000000000000000000000000000000001544 147.0
HFD2_k127_6979452_2 - - - - 0.000000001465 64.0
HFD2_k127_6979452_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0001373 48.0
HFD2_k127_6995695_0 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009288 282.0
HFD2_k127_6995695_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000006197 171.0
HFD2_k127_6995695_2 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000007741 130.0
HFD2_k127_6998957_0 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 478.0
HFD2_k127_6998957_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 293.0
HFD2_k127_6998957_2 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000006589 251.0
HFD2_k127_6998957_3 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000003063 215.0
HFD2_k127_6998957_4 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000002149 125.0
HFD2_k127_7005488_0 PFAM Type II secretion system protein E K02652 - - 1.835e-230 725.0
HFD2_k127_7005488_1 Pilus assembly protein K02662 - - 0.0000000000001769 77.0
HFD2_k127_7005488_2 Pilus assembly protein K02662 - - 0.0000000008009 72.0
HFD2_k127_7012682_0 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000225 223.0
HFD2_k127_7012682_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000009902 177.0
HFD2_k127_7012682_2 nucleotidyltransferase activity - - - 0.000000000000000000000000000000001935 138.0
HFD2_k127_7024783_0 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000001022 175.0
HFD2_k127_7024783_1 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000002934 173.0
HFD2_k127_7024981_0 AcrB/AcrD/AcrF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 537.0
HFD2_k127_7024981_1 Outer membrane efflux protein K15725 - - 0.00000000000000000000000000000835 133.0
HFD2_k127_7024981_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000003905 81.0
HFD2_k127_703681_0 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001603 253.0
HFD2_k127_703681_1 PFAM Mannosyl oligosaccharide glucosidase - - - 0.0000000000000000000000000000000000000000000002046 168.0
HFD2_k127_703681_2 Putative zinc-finger - - - 0.000004527 53.0
HFD2_k127_703741_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.722e-221 711.0
HFD2_k127_703741_1 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005614 433.0
HFD2_k127_703741_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000001493 220.0
HFD2_k127_703741_3 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000005444 142.0
HFD2_k127_703741_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000665 110.0
HFD2_k127_703741_5 Protein of unknown function (DUF503) K09764 - - 0.000000000000000006517 87.0
HFD2_k127_7043730_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000004823 172.0
HFD2_k127_7043730_1 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000001789 174.0
HFD2_k127_7055785_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007583 460.0
HFD2_k127_7055785_1 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000001788 152.0
HFD2_k127_7055785_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000003952 138.0
HFD2_k127_7055785_3 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.000000000000000000003927 96.0
HFD2_k127_7055785_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000003248 81.0
HFD2_k127_705958_0 Uncharacterized protein conserved in bacteria (DUF2334) - - - 0.000000000000000000000000000000000000000000000000000000009041 216.0
HFD2_k127_705958_1 Sulfatase - - - 0.0000000000000000000000000000000001453 151.0
HFD2_k127_705958_2 lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.000000000000000000000000000007545 132.0
HFD2_k127_7077706_0 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 315.0
HFD2_k127_7077706_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000008952 206.0
HFD2_k127_7077706_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000002089 114.0
HFD2_k127_7081173_0 Heparinase II/III-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 407.0
HFD2_k127_7081173_1 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 338.0
HFD2_k127_7081173_2 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000689 221.0
HFD2_k127_7084211_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.68e-306 959.0
HFD2_k127_7084211_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000003912 272.0
HFD2_k127_7084211_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000007154 205.0
HFD2_k127_7089407_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003426 282.0
HFD2_k127_7089407_1 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000005616 269.0
HFD2_k127_7089407_2 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000409 108.0
HFD2_k127_7110499_0 squalene-associated FAD-dependent desaturase K21677 - 1.17.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000003903 254.0
HFD2_k127_7111104_0 Domain of unknown function (DUF3394) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 406.0
HFD2_k127_7111104_1 TRAP transporter solute receptor TAXI family K07080 - - 0.000000000000000000000473 96.0
HFD2_k127_7111104_2 Domain of unknown function (DUF1850) - - - 0.00001112 54.0
HFD2_k127_7113246_0 ABC transporter K06022,K06158,K10834 - 3.6.3.29,3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 491.0
HFD2_k127_7113246_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 415.0
HFD2_k127_7113246_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 322.0
HFD2_k127_7113246_3 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000006819 130.0
HFD2_k127_7113246_4 - - - - 0.0000000005772 64.0
HFD2_k127_7114733_0 aminopeptidase activity K01301 - 3.4.17.21 4.928e-202 648.0
HFD2_k127_7114733_1 UPF0056 membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002329 244.0
HFD2_k127_7114733_2 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000001904 197.0
HFD2_k127_712693_0 ASPIC and UnbV - - - 1.942e-196 632.0
HFD2_k127_712693_1 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00002609 49.0
HFD2_k127_7129505_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 498.0
HFD2_k127_7129505_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000005693 196.0
HFD2_k127_7129505_2 - - - - 0.000000000000000000000000000000000000002313 154.0
HFD2_k127_7129505_3 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000000157 136.0
HFD2_k127_7129505_4 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000001896 66.0
HFD2_k127_7129505_5 ATP-dependent DNA helicase K03657 GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.0006139 49.0
HFD2_k127_713074_0 Peptidase dimerisation domain K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 478.0
HFD2_k127_713074_1 Saccharopine dehydrogenase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 407.0
HFD2_k127_713074_2 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000242 227.0
HFD2_k127_7161247_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009649 522.0
HFD2_k127_7161247_1 Transposase - - - 0.000004244 53.0
HFD2_k127_7175082_0 PFAM Anthranilate synthase component I K01657,K01665 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 369.0
HFD2_k127_7175082_1 Haloacid dehalogenase-like hydrolase K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000002101 228.0
HFD2_k127_7175082_2 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.0000000000000000000000000007632 116.0
HFD2_k127_7175082_3 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000003455 96.0
HFD2_k127_7175082_4 membrane K11622 - - 0.0000000000000000123 95.0
HFD2_k127_7175082_5 peroxiredoxin activity - - - 0.000000000000001567 79.0
HFD2_k127_7175082_6 - - - - 0.00001418 55.0
HFD2_k127_7183702_0 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 477.0
HFD2_k127_7183702_1 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 406.0
HFD2_k127_7183702_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601,K03797 - 3.1.11.6,3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 383.0
HFD2_k127_7183702_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 351.0
HFD2_k127_7183702_4 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017 327.0
HFD2_k127_7183702_5 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000003004 187.0
HFD2_k127_7183702_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000002509 86.0
HFD2_k127_7183702_7 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000003332 78.0
HFD2_k127_71908_0 Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 3.343e-201 651.0
HFD2_k127_71908_1 Prolyl oligopeptidase family K06889 - - 0.0000000000000000000000000000001438 134.0
HFD2_k127_7192907_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 2.984e-198 636.0
HFD2_k127_7192907_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000003169 290.0
HFD2_k127_722176_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000009122 86.0
HFD2_k127_722176_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000229 51.0
HFD2_k127_7227526_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.562e-282 878.0
HFD2_k127_7236579_0 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 316.0
HFD2_k127_7236579_1 SMART Tetratricopeptide domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007149 278.0
HFD2_k127_7236579_2 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000000000002118 73.0
HFD2_k127_7236579_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000002665 65.0
HFD2_k127_7236579_4 - - - - 0.0001855 52.0
HFD2_k127_723964_0 Radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 393.0
HFD2_k127_723964_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000001084 270.0
HFD2_k127_723964_2 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000008399 180.0
HFD2_k127_7260164_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 572.0
HFD2_k127_7260164_1 Ftsk_gamma K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 537.0
HFD2_k127_7260164_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.182 0.00000000000000000000000000000000000000000000000002922 189.0
HFD2_k127_7260164_3 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000001443 111.0
HFD2_k127_7269140_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 497.0
HFD2_k127_7269140_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 386.0
HFD2_k127_7280048_0 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000002862 148.0
HFD2_k127_7280048_1 TPM domain K06872 - - 0.0000000000000000000000001295 117.0
HFD2_k127_7286769_0 Type ii and iii secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 335.0
HFD2_k127_7286769_1 Pilus assembly protein, PilO K02664 - - 0.000006975 58.0
HFD2_k127_728886_0 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 1.299e-199 629.0
HFD2_k127_728886_1 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 331.0
HFD2_k127_7307547_0 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 308.0
HFD2_k127_7307547_1 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000007257 224.0
HFD2_k127_7307547_2 Multidrug ABC transporter permease K02004 - - 0.000000000000000000000002444 106.0
HFD2_k127_7307802_0 PA domain - - - 0.00000000000000000000000001531 119.0
HFD2_k127_7307802_1 - - - - 0.000000000000000000000003693 117.0
HFD2_k127_7307802_3 OmpA-like transmembrane domain - - - 0.000000000002093 80.0
HFD2_k127_731961_0 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 302.0
HFD2_k127_731961_1 protein histidine kinase activity K06375 - - 0.000000000000002138 80.0
HFD2_k127_7320598_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000001244 134.0
HFD2_k127_7320598_1 Domain of unknown function (DUF4136) - - - 0.00000000000000000000000000005536 123.0
HFD2_k127_7320598_2 - - - - 0.0000000000000000000000007571 109.0
HFD2_k127_7320598_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000001857 93.0
HFD2_k127_7332365_0 iron-nicotianamine transmembrane transporter activity - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.000000000000000000000000000000000000000000000000000000000000001133 223.0
HFD2_k127_7344944_0 PFAM regulatory protein LuxR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001605 267.0
HFD2_k127_7344944_1 PRC-barrel domain - - - 0.00000000000000000000000000000000008347 136.0
HFD2_k127_7344944_2 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000002264 117.0
HFD2_k127_7344944_3 4Fe-4S single cluster domain - - - 0.000004449 53.0
HFD2_k127_7363176_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 385.0
HFD2_k127_7363176_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000001305 226.0
HFD2_k127_7363176_2 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000302 203.0
HFD2_k127_736360_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000292 231.0
HFD2_k127_7372333_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003882 266.0
HFD2_k127_7372333_1 NAD dependent epimerase dehydratase family K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000008134 190.0
HFD2_k127_7383500_0 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000811 456.0
HFD2_k127_7383500_1 regulation of translation K05808,K05809 GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006446,GO:0006448,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000001258 133.0
HFD2_k127_7383500_2 Branched-chain amino acid ATP-binding cassette transporter K06861 - - 0.000000000002579 67.0
HFD2_k127_7394084_0 PhoQ Sensor - - - 0.000000000000000000000000000000000003105 151.0
HFD2_k127_7394084_1 spore germination - - - 0.0000000000000000000000022 114.0
HFD2_k127_7394084_2 Protein of unknown function (DUF2905) - - - 0.00000000000000005005 82.0
HFD2_k127_7400853_0 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 433.0
HFD2_k127_7400853_1 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000004369 172.0
HFD2_k127_7417759_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 5.584e-296 924.0
HFD2_k127_7417759_1 serine-type peptidase activity K01278 - 3.4.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008382 525.0
HFD2_k127_7419308_0 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 391.0
HFD2_k127_7419576_0 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000005183 238.0
HFD2_k127_7419576_1 D,d-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000001883 221.0
HFD2_k127_7419576_2 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000006261 70.0
HFD2_k127_7441553_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 2.781e-270 837.0
HFD2_k127_7444151_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008478 582.0
HFD2_k127_7444151_1 YceI-like domain - - - 0.00000000000000000000000000000000865 136.0
HFD2_k127_7457378_0 FeS assembly protein SufD K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 467.0
HFD2_k127_7457378_1 FeS assembly ATPase SufC K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 391.0
HFD2_k127_7457378_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000004142 154.0
HFD2_k127_7457378_3 iron-sulfur cluster assembly K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 0.000000000000003371 74.0
HFD2_k127_747719_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 389.0
HFD2_k127_747719_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003891 251.0
HFD2_k127_747719_2 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.00000000000000000000000000000000000000000000000000000000005246 205.0
HFD2_k127_747719_3 Matrixin - - - 0.00000001375 69.0
HFD2_k127_7485630_0 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 454.0
HFD2_k127_7485630_1 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007872 369.0
HFD2_k127_7485630_2 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.0000000000000000000000000000000000000000000000006489 180.0
HFD2_k127_7485630_3 formate dehydrogenase - - - 0.00000000000000000000000000000000000006843 151.0
HFD2_k127_7485630_4 amine dehydrogenase activity K21449 - - 0.0000000000000000000000000000000000002896 147.0
HFD2_k127_7485630_5 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000001528 116.0
HFD2_k127_751711_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 351.0
HFD2_k127_751711_1 tigr00255 - - - 0.000000000000000000000000000000000001179 153.0
HFD2_k127_751711_2 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000001287 145.0
HFD2_k127_7532329_0 DNA polymerase type-B family K02336 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 463.0
HFD2_k127_7547229_0 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 364.0
HFD2_k127_7547229_1 Protein of unknown function (DUF2400) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001219 261.0
HFD2_k127_7547229_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000002316 94.0
HFD2_k127_7547229_3 DSBA-like thioredoxin domain - - - 0.0001563 52.0
HFD2_k127_7552381_0 Tetratricopeptide repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 337.0
HFD2_k127_7552381_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000008911 230.0
HFD2_k127_7552381_2 Transmembrane and TPR repeat-containing protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0008150,GO:0012505,GO:0016020,GO:0031984,GO:0042175,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0048878,GO:0050801,GO:0055065,GO:0055074,GO:0055080,GO:0065007,GO:0065008,GO:0072507,GO:0098771,GO:0098827 - 0.00000000000000000000000000000000000000000000000000000001315 222.0
HFD2_k127_7552381_3 TonB dependent receptor K16089 - - 0.000000001321 71.0
HFD2_k127_7554095_0 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 329.0
HFD2_k127_7564346_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000856 371.0
HFD2_k127_7564346_1 CHASE3 domain K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 296.0
HFD2_k127_7564346_2 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 298.0
HFD2_k127_7564346_3 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000005152 140.0
HFD2_k127_7564346_4 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000002936 113.0
HFD2_k127_7564346_5 Cytochrome C' - - - 0.000003923 56.0
HFD2_k127_7564691_0 Seven times multi-haem cytochrome CxxCH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 503.0
HFD2_k127_7564691_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009849 386.0
HFD2_k127_7564691_2 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.00000000000000000000000000000000000000000000000000261 191.0
HFD2_k127_7564691_3 Glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000000000003617 194.0
HFD2_k127_7564691_4 Glutaredoxin - - - 0.0000000000000000000000000000004846 128.0
HFD2_k127_7564691_5 NADH-Ubiquinone oxidoreductase (complex I), chain 5 K00341 - 1.6.5.3 0.0000000000000000000009856 98.0
HFD2_k127_7564691_6 Belongs to the BolA IbaG family - - - 0.0000000000000001183 86.0
HFD2_k127_7570580_0 Protein kinase domain K12132 - 2.7.11.1 1.235e-217 710.0
HFD2_k127_7570580_1 Protein kinase domain K12132 - 2.7.11.1 3.43e-216 700.0
HFD2_k127_7570580_2 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 598.0
HFD2_k127_7570580_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 574.0
HFD2_k127_7570580_4 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 562.0
HFD2_k127_7570580_5 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000000000000000000005235 112.0
HFD2_k127_7571666_0 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000002213 241.0
HFD2_k127_7571666_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000000000000000001236 194.0
HFD2_k127_7571666_2 Peptidase family M1 domain - - - 0.00000000000000001158 98.0
HFD2_k127_7607849_0 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 298.0
HFD2_k127_7607849_1 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003483 262.0
HFD2_k127_7607849_2 - - - - 0.00000000000000000000000000000000000000000000000000000001772 204.0
HFD2_k127_7607849_3 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000218 136.0
HFD2_k127_7607849_4 Sulfurtransferase - - - 0.000000000000000000001192 95.0
HFD2_k127_7607849_5 Putative zinc-finger - - - 0.00000004452 57.0
HFD2_k127_7609075_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1059.0
HFD2_k127_7609075_1 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007897 555.0
HFD2_k127_7609075_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000201 284.0
HFD2_k127_7609075_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008451 248.0
HFD2_k127_7609075_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000765 228.0
HFD2_k127_7609075_5 Cytochrome c K00406 - - 0.000000000001191 76.0
HFD2_k127_7609075_6 Cytochrome b/b6/petB - - - 0.0000003074 56.0
HFD2_k127_7609354_0 PFAM Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005998 270.0
HFD2_k127_7609354_1 Tetratricopeptide repeat - - - 0.000000000000000000000000129 116.0
HFD2_k127_7609354_2 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.00000000000000000005439 93.0
HFD2_k127_7613053_0 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 434.0
HFD2_k127_7613053_1 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000004497 178.0
HFD2_k127_7613053_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000001792 126.0
HFD2_k127_7613053_3 Sphaeroforma arctica JP610 - - - 0.00001326 55.0
HFD2_k127_7628239_0 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 501.0
HFD2_k127_7628239_1 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000009947 88.0
HFD2_k127_7635253_0 Oligopeptide transporter OPT - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 564.0
HFD2_k127_7635253_1 PFAM Amino acid K20265 - - 0.0000000000000000000000000000000000000000000000000000000000004602 220.0
HFD2_k127_7635544_0 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 8.139e-251 796.0
HFD2_k127_7635544_1 Fe-S cluster domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 336.0
HFD2_k127_7635544_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000001979 170.0
HFD2_k127_7635544_3 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000001345 153.0
HFD2_k127_7635544_4 DRTGG domain - - - 0.0000000000000000000000007634 107.0
HFD2_k127_7635544_5 DRTGG domain - - - 0.00000000000000000001205 95.0
HFD2_k127_7635544_7 - - - - 0.0001268 44.0
HFD2_k127_7635544_8 Pyridine nucleotide-disulphide oxidoreductase K00123 - 1.17.1.9 0.0002456 48.0
HFD2_k127_7640231_0 Pfam:Arch_ATPase - - - 0.0000000000000000000000000000000000000000000000000000000003084 229.0
HFD2_k127_7640231_1 - K06921 - - 0.00000000000000000000000000000000000000000000000899 183.0
HFD2_k127_7640231_2 aconitate hydratase K01681 - 4.2.1.3 0.000000000000008782 74.0
HFD2_k127_7640231_3 Peptidase C13 family - - - 0.00000000003887 77.0
HFD2_k127_7668360_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002909 260.0
HFD2_k127_7668360_1 Flavin containing amine oxidoreductase K00231,K01854 - 1.3.3.15,1.3.3.4,5.4.99.9 0.00000000000000000000000000000000000000000000436 171.0
HFD2_k127_768079_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 512.0
HFD2_k127_768079_1 TIGRFAM signal peptidase I K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000005459 179.0
HFD2_k127_7716054_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000003638 104.0
HFD2_k127_7716054_1 PFAM glycoside hydrolase family 39 - - - 0.00001983 58.0
HFD2_k127_7716054_2 antisigma factor binding - - - 0.0007214 53.0
HFD2_k127_773035_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 414.0
HFD2_k127_773035_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000002891 207.0
HFD2_k127_773035_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000003195 188.0
HFD2_k127_773035_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000002735 169.0
HFD2_k127_7740154_0 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 298.0
HFD2_k127_7740154_1 PFAM Roadblock LC7 family protein - - - 0.000000000000000000000000000000000000000000000000007506 187.0
HFD2_k127_7740154_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000001858 119.0
HFD2_k127_7740154_3 PFAM Uncharacterised protein family (UPF0153) - - - 0.00000000000000005493 85.0
HFD2_k127_7740154_4 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.0000000005677 65.0
HFD2_k127_7748142_0 chaperone-mediated protein folding - - - 0.00000000000000000000000000000000000000000000002503 193.0
HFD2_k127_7748142_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000001784 169.0
HFD2_k127_7748142_2 PFAM Glycosyl transferase family 2 - - - 0.0001539 53.0
HFD2_k127_7748641_0 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 293.0
HFD2_k127_7748641_1 metalloendopeptidase activity K01283 - 3.4.15.1 0.00000000000000000000000000000000000000000000000000000000000000002119 237.0
HFD2_k127_7748641_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000001887 108.0
HFD2_k127_7748641_3 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000009453 80.0
HFD2_k127_7748641_4 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000008791 62.0
HFD2_k127_7750038_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000001101 179.0
HFD2_k127_7758882_0 PFAM Peptidase family M28 - - - 0.00000000000000000000000000000000003086 149.0
HFD2_k127_7805897_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000001231 231.0
HFD2_k127_7805897_1 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000000000001026 180.0
HFD2_k127_7805897_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000004114 167.0
HFD2_k127_7805897_3 GTP cyclohydrolase K01495 - 3.5.4.16 0.0000000000000000000000000000000000000106 155.0
HFD2_k127_7805897_4 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000003714 145.0
HFD2_k127_7821018_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 356.0
HFD2_k127_7821018_1 e3 binding domain K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 305.0
HFD2_k127_7821018_2 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 303.0
HFD2_k127_7821018_3 Biotin/lipoate A/B protein ligase family K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000001902 228.0
HFD2_k127_7836478_0 Alanine dehydrogenase/PNT, N-terminal domain K00290,K14157 - 1.5.1.7,1.5.1.8,1.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 397.0
HFD2_k127_7836478_1 Long-chain acyl-CoA - - - 0.00000009388 63.0
HFD2_k127_7839099_0 Protein of unknown function (DUF4255) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 601.0
HFD2_k127_7839099_1 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001032 267.0
HFD2_k127_7840970_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 542.0
HFD2_k127_7840970_1 TonB-dependent Receptor Plug Domain K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 475.0
HFD2_k127_7908153_0 PFAM CoA-binding domain protein K06929 - - 0.0000000000000000000000000000000000000001286 162.0
HFD2_k127_7908153_1 peptidase - - - 0.000000000000000000000004906 111.0
HFD2_k127_7911911_0 Amylo-alpha-1,6-glucosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 452.0
HFD2_k127_7911911_1 ligase activity, forming nitrogen-metal bonds K02230,K03403 - 6.6.1.1,6.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 425.0
HFD2_k127_791293_0 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001114 290.0
HFD2_k127_791293_1 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001957 250.0
HFD2_k127_791293_2 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002433 247.0
HFD2_k127_791293_3 hydrolase of the alpha beta-hydrolase fold K07019 GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0050526,GO:0052689,GO:0071704 - 0.00000000000000000000000000000000000000000001224 175.0
HFD2_k127_7921353_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 2.434e-216 690.0
HFD2_k127_7921353_1 Peptidase M50 K16922 - - 0.0000000000000000000000000000000000000000000000000000001294 202.0
HFD2_k127_7921353_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000001112 164.0
HFD2_k127_7948587_0 Zn-dependent protease with chaperone function K03799,K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 400.0
HFD2_k127_7948587_1 DNA polymerase type-B family K02336 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000002152 220.0
HFD2_k127_7957584_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 440.0
HFD2_k127_7957584_1 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 319.0
HFD2_k127_7957584_2 RNA 2'-O ribose methyltransferase substrate binding K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.0000000000000000000000000000000000000000000000000009154 192.0
HFD2_k127_7984411_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1367.0
HFD2_k127_7984411_1 HlyD family secretion protein K03585 - - 0.0000000000000000000000000002478 117.0
HFD2_k127_7984411_2 CHAT domain - - - 0.00000006864 53.0
HFD2_k127_7987785_0 Cytochrome C assembly protein - - - 1.019e-256 814.0
HFD2_k127_7987785_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 370.0
HFD2_k127_7987785_2 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005419 285.0
HFD2_k127_7993908_0 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 299.0
HFD2_k127_7993908_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000001424 257.0
HFD2_k127_7993908_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000009987 182.0
HFD2_k127_7993908_3 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.00000000002358 67.0
HFD2_k127_7993908_4 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000001271 61.0
HFD2_k127_7993908_5 outer membrane autotransporter barrel domain protein - - - 0.000006523 58.0
HFD2_k127_8001061_0 DNA polymerase K02347 - - 5.948e-236 744.0
HFD2_k127_8001061_1 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009157 364.0
HFD2_k127_8001061_2 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) K07259 - 3.4.16.4 0.00000000000000000004457 101.0
HFD2_k127_8002976_0 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) - - - 0.0000000000000000000000000000000000000000001818 179.0
HFD2_k127_8002976_1 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.000000000000000000008496 102.0
HFD2_k127_8002976_2 GDSL-like Lipase/Acylhydrolase - - - 0.0000000001734 74.0
HFD2_k127_8005146_0 Alpha amylase, catalytic domain - - - 0.0 1171.0
HFD2_k127_8005146_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975,K01214 - 2.7.7.27,3.2.1.68 0.00000000000000000000000000000000000000000000000000000006373 203.0
HFD2_k127_8014153_0 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 3.83e-249 786.0
HFD2_k127_8014153_1 Domain of unknown function (DUF3463) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 444.0
HFD2_k127_8014153_2 NmrA-like family K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 397.0
HFD2_k127_8014153_3 Carotenoid biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000001165 224.0
HFD2_k127_8081630_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 - 1.17.1.4 3.895e-206 664.0
HFD2_k127_8081630_1 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 295.0
HFD2_k127_8081630_2 2Fe-2S -binding domain K13483 - - 0.0000000000000000000000000000000000000000000000008434 182.0
HFD2_k127_8081630_3 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000001797 178.0
HFD2_k127_8081630_4 molybdenum cofactor guanylyltransferase activity K03752,K13818 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77 0.00000004122 63.0
HFD2_k127_809712_0 ABC transporter transmembrane K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 311.0
HFD2_k127_809712_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 296.0
HFD2_k127_809712_2 Forkhead associated domain - - - 0.0001392 50.0
HFD2_k127_8106466_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 290.0
HFD2_k127_8106466_1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000001155 156.0
HFD2_k127_8106466_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000004949 127.0
HFD2_k127_8106466_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000001787 83.0
HFD2_k127_8123594_0 Transcriptional regulator K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000002675 244.0
HFD2_k127_8153219_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 321.0
HFD2_k127_8153219_1 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006193 304.0
HFD2_k127_8153219_2 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000009293 141.0
HFD2_k127_8153219_3 DNA-binding transcription factor activity K03892,K21903 - - 0.0000000000000000000001932 101.0
HFD2_k127_8153219_4 aminopeptidase activity K01301 - 3.4.17.21 0.000000000000000000007278 96.0
HFD2_k127_8153219_5 Tetratricopeptide repeat - - - 0.00000117 61.0
HFD2_k127_8158869_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 6.035e-204 649.0
HFD2_k127_8173757_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 370.0
HFD2_k127_8186887_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 296.0
HFD2_k127_8186887_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0004263 51.0
HFD2_k127_8194995_0 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 544.0
HFD2_k127_8194995_2 Bacterial transferase hexapeptide (six repeats) K13018 - 2.3.1.201 0.000000000000000000006658 105.0
HFD2_k127_8194995_3 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000001881 99.0
HFD2_k127_8202029_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 444.0
HFD2_k127_8202029_1 peptidase K07386 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 361.0
HFD2_k127_8202029_2 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000000000000000005474 196.0
HFD2_k127_8202029_3 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000007986 159.0
HFD2_k127_8202029_4 - - - - 0.0000000000000000000000001209 121.0
HFD2_k127_8202379_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000008597 155.0
HFD2_k127_8202379_1 COG3209 Rhs family protein - - - 0.0000000000007282 81.0
HFD2_k127_8206092_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 479.0
HFD2_k127_8206092_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007896 404.0
HFD2_k127_8206092_2 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.4.2.9 0.00000000000000008147 81.0
HFD2_k127_8208618_0 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000005481 184.0
HFD2_k127_8208618_1 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000003097 130.0
HFD2_k127_8208618_2 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000025 105.0
HFD2_k127_8208618_3 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0008996 43.0
HFD2_k127_821716_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008827 387.0
HFD2_k127_821716_1 - - - - 0.000000000000000000000000156 112.0
HFD2_k127_821716_2 Flavin reductase like domain - - - 0.0000000000000000000000008198 114.0
HFD2_k127_8228220_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000001288 236.0
HFD2_k127_8228220_1 Kelch motif - GO:0000003,GO:0000228,GO:0000280,GO:0000785,GO:0000790,GO:0003674,GO:0003682,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005730,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006986,GO:0006996,GO:0007049,GO:0007127,GO:0007131,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010033,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022402,GO:0022414,GO:0022613,GO:0023052,GO:0030968,GO:0031974,GO:0031981,GO:0033554,GO:0034470,GO:0034620,GO:0034641,GO:0034660,GO:0034976,GO:0035825,GO:0035966,GO:0035967,GO:0036498,GO:0042221,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044454,GO:0044464,GO:0046483,GO:0048285,GO:0050789,GO:0050794,GO:0050896,GO:0051321,GO:0051716,GO:0061982,GO:0065007,GO:0070013,GO:0070887,GO:0071310,GO:0071704,GO:0071840,GO:0090304,GO:0140013,GO:1901360,GO:1903046 - 0.00000000009534 76.0
HFD2_k127_8230628_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175,K00177,K00187 - 1.2.7.11,1.2.7.3,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 527.0
HFD2_k127_8230628_1 alanine dehydrogenase activity K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008449 323.0
HFD2_k127_8230628_2 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000001323 238.0
HFD2_k127_8230628_3 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000001148 121.0
HFD2_k127_8230628_4 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000003979 64.0
HFD2_k127_823618_0 Fungalysin metallopeptidase (M36) - - - 0.0 1100.0
HFD2_k127_824343_0 Ribosomal protein S1 K02945,K03527,K07571 - 1.17.7.4 1.715e-214 684.0
HFD2_k127_824343_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 432.0
HFD2_k127_824343_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 324.0
HFD2_k127_824343_3 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000007038 189.0
HFD2_k127_824343_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000000000000119 135.0
HFD2_k127_824343_5 Belongs to the pseudouridine synthase RsuA family K06181 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20 0.000000000000000007943 86.0
HFD2_k127_8253818_0 peptidyl-tyrosine sulfation - - - 0.00002213 57.0
HFD2_k127_8256015_0 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008508 559.0
HFD2_k127_8256015_1 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 510.0
HFD2_k127_8256015_2 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 468.0
HFD2_k127_8256015_3 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 353.0
HFD2_k127_8256015_4 - - - - 0.00000000000000000000004096 109.0
HFD2_k127_8256015_5 PFAM sulfatase K01130 - 3.1.6.1 0.000000000000000000002528 94.0
HFD2_k127_8256015_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000002525 97.0
HFD2_k127_8263030_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 368.0
HFD2_k127_8263030_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000106 169.0
HFD2_k127_8263030_2 Tetratricopeptide - - - 0.00001082 53.0
HFD2_k127_8284035_0 ggdef domain - - - 0.0000000000000000000000000000000000000000000000000000004094 208.0
HFD2_k127_8284035_1 Glycoprotease family K01409,K14742 - 2.3.1.234 0.00000000000000000000000000000000003574 142.0
HFD2_k127_8284035_2 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000006794 123.0
HFD2_k127_8284035_3 diguanylate cyclase - - - 0.00000005734 63.0
HFD2_k127_8290204_0 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.00000000000000000000000000000000000000000000000000009075 203.0
HFD2_k127_8290204_1 metalloendopeptidase activity K08602 - - 0.0000000000000000000000000000000000000000004203 169.0
HFD2_k127_8290204_2 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000003368 127.0
HFD2_k127_8290204_3 lyase activity - - - 0.000000000000000000000009515 118.0
HFD2_k127_8290204_4 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000001228 82.0
HFD2_k127_8290204_5 Tetratricopeptide repeat - - - 0.00000006645 61.0
HFD2_k127_8307061_0 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 530.0
HFD2_k127_8307061_1 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 391.0
HFD2_k127_8307061_2 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000002457 177.0
HFD2_k127_8307061_3 Redoxin K03564 - 1.11.1.15 0.0000000006399 61.0
HFD2_k127_8315119_0 Heat shock 70 kDa protein K04043 - - 8.588e-299 929.0
HFD2_k127_8315119_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000008155 149.0
HFD2_k127_8334437_0 Tryptophan 2,3-dioxygenase K00453 - 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 339.0
HFD2_k127_8334437_1 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.0000000000000000000000000000000000000000000001088 176.0
HFD2_k127_8334437_2 Belongs to the 'phage' integrase family - - - 0.000001994 54.0
HFD2_k127_8338761_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000004922 254.0
HFD2_k127_8338761_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000004678 184.0
HFD2_k127_8338761_2 Glycosyl transferases group 1 - - - 0.00001066 55.0
HFD2_k127_8347670_0 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 383.0
HFD2_k127_8347700_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000001896 231.0
HFD2_k127_8347700_1 - - - - 0.00000001641 62.0
HFD2_k127_8347700_2 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000366 63.0
HFD2_k127_8358499_0 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 374.0
HFD2_k127_8358499_1 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000006619 153.0
HFD2_k127_8358499_2 hopanoid biosynthesis associated protein HpnK - - - 0.000000000000000000000000000000000002259 148.0
HFD2_k127_8358499_3 LysE type translocator - - - 0.00000000000000001309 85.0
HFD2_k127_8358499_4 conserved protein (DUF2203) - - - 0.00000000000000001365 90.0
HFD2_k127_8363536_0 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 432.0
HFD2_k127_8381748_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 7.958e-218 692.0
HFD2_k127_8381748_1 thiosulfate sulfurtransferase activity K01011 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 461.0
HFD2_k127_8381748_10 Protein tyrosine kinase - - - 0.00004757 55.0
HFD2_k127_8381748_2 RNA pseudouridylate synthase K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 348.0
HFD2_k127_8381748_3 Thrombospondin type 3 repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 306.0
HFD2_k127_8381748_4 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000001013 177.0
HFD2_k127_8381748_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000000000000000000003323 160.0
HFD2_k127_8381748_6 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.00000000000000000000000000000000000005493 148.0
HFD2_k127_8381748_8 Protein of unknown function (DUF983) - - - 0.000000000000000000002944 97.0
HFD2_k127_8381748_9 Adenylate cyclase - - - 0.0000003067 63.0
HFD2_k127_8382509_0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.00000000000000000000007794 104.0
HFD2_k127_8382509_1 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000001327 76.0
HFD2_k127_8385392_0 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000001514 153.0
HFD2_k127_8385392_1 PrkA AAA domain K07180 - - 0.000001032 53.0
HFD2_k127_8385392_2 Putative zinc-finger - - - 0.0001865 51.0
HFD2_k127_8388187_0 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 1.494e-230 724.0
HFD2_k127_8388187_1 Protein of unknown function (DUF1579) - - - 0.000000000000000000000000002958 116.0
HFD2_k127_839845_0 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000006069 221.0
HFD2_k127_839845_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000006282 140.0
HFD2_k127_839845_2 TIGRFAM chain length determinant protein EpsF - - - 0.00006996 53.0
HFD2_k127_8414057_0 peptidase S9 prolyl oligopeptidase active site - GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 3.437e-276 863.0
HFD2_k127_8414057_1 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006757 551.0
HFD2_k127_8414057_2 Iron-storage protein K02217 - 1.16.3.2 0.00000000000000000000000000000000444 136.0
HFD2_k127_8414057_3 Protein of unknown function (DUF3303) - - - 0.00000000000000000000000000000009151 127.0
HFD2_k127_8414057_4 NnrU protein - - - 0.000000000000000000817 96.0
HFD2_k127_8417558_0 cellulose binding - - - 0.0 1338.0
HFD2_k127_8417558_1 PFAM Alcohol dehydrogenase - - - 0.00000000009342 69.0
HFD2_k127_8417558_2 Transposase - - - 0.000003133 55.0
HFD2_k127_8424195_0 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000008236 190.0
HFD2_k127_8424195_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000001604 110.0
HFD2_k127_8432171_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008622 491.0
HFD2_k127_8432171_1 RelA SpoT domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 354.0
HFD2_k127_8432171_2 Formyl transferase K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000008774 198.0
HFD2_k127_8432171_3 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000002333 183.0
HFD2_k127_8432171_4 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000004493 97.0
HFD2_k127_8441287_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.356e-247 775.0
HFD2_k127_8441287_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000001471 134.0
HFD2_k127_8441967_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1073.0
HFD2_k127_8441967_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 572.0
HFD2_k127_8441967_2 SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006351 389.0
HFD2_k127_8441967_3 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000004729 237.0
HFD2_k127_8441967_4 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000000002254 184.0
HFD2_k127_8443522_0 KduI/IolB family K03337 - 5.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 339.0
HFD2_k127_8443522_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000009565 246.0
HFD2_k127_8443522_2 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000003844 136.0
HFD2_k127_8443522_3 Cupin 2, conserved barrel domain protein - - - 0.000001418 56.0
HFD2_k127_8468719_0 Tricorn protease C1 domain K08676 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 432.0
HFD2_k127_8468719_1 Di-glucose binding within endoplasmic reticulum - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 374.0
HFD2_k127_8477382_0 Tricorn protease C1 domain K08676 - - 6.753e-282 911.0
HFD2_k127_8477382_1 exo-alpha-(2->6)-sialidase activity - - - 1.225e-269 874.0
HFD2_k127_8477382_2 multicopper oxidases K06324 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000288 250.0
HFD2_k127_8477382_3 Protein of unknown function (DUF2585) - - - 0.000000000000000000000000000000000000000000000000004903 188.0
HFD2_k127_8477382_4 divalent heavy-metal cations transporter K07238 - - 0.00000000008083 67.0
HFD2_k127_8477382_5 PFAM Uncharacterised BCR, COG1649 - - - 0.0000008444 63.0
HFD2_k127_8480851_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005681 514.0
HFD2_k127_8480851_1 WD-40 repeat - - - 0.0000003741 62.0
HFD2_k127_8482821_0 Pyridine nucleotide-disulphide oxidoreductase K00335 - 1.6.5.3 1.92e-225 711.0
HFD2_k127_8514143_0 Glycosyl hydrolase-like 10 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006073 273.0
HFD2_k127_8514143_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000001299 117.0
HFD2_k127_8520954_0 nitrogen compound transport K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 339.0
HFD2_k127_8520954_1 Response receiver-modulated cyclic diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 326.0
HFD2_k127_8520954_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001477 284.0
HFD2_k127_8534503_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.466e-221 702.0
HFD2_k127_8534503_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006877 385.0
HFD2_k127_8534503_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000002362 273.0
HFD2_k127_8534503_3 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003001 261.0
HFD2_k127_8534503_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000001486 222.0
HFD2_k127_8534503_5 Cytochrome oxidase assembly protein K02259 - - 0.00000000000000000000000000000000000000000001272 175.0
HFD2_k127_853983_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006923 453.0
HFD2_k127_853983_1 Lysylphosphatidylglycerol synthase TM region K07027,K14205 - 2.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009963 349.0
HFD2_k127_853983_2 PFAM virulence factor family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006891 305.0
HFD2_k127_8540112_0 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 434.0
HFD2_k127_8540112_1 Antioxidant, AhpC TSA family - - - 0.00000000000000127 80.0
HFD2_k127_8552181_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 393.0
HFD2_k127_8552181_1 SNARE associated Golgi protein - - - 0.0000000000000000000000002844 113.0
HFD2_k127_8552181_2 Tetratricopeptide repeat - - - 0.000000000000000008269 93.0
HFD2_k127_8552181_3 FecR protein - - - 0.00000000001147 77.0
HFD2_k127_8570144_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 403.0
HFD2_k127_8570144_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000114 89.0
HFD2_k127_8570144_2 Histidine kinase - - - 0.000002733 55.0
HFD2_k127_8570144_3 cell wall anchor domain - - - 0.0003098 54.0
HFD2_k127_8572340_0 arylsulfatase activity K07014 - - 0.000000000000000000000000000000000001491 155.0
HFD2_k127_8586913_0 Lipase maturation factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 345.0
HFD2_k127_8586913_2 Transmembrane proteins 14C - - - 0.000000000000006675 85.0
HFD2_k127_8586913_3 - - - - 0.0000000000266 69.0
HFD2_k127_8586913_4 Domain of unknown function (DUF5118) - - - 0.0000000003156 68.0
HFD2_k127_8593344_0 Prokaryotic N-terminal methylation motif - - - 0.0000000000003667 75.0
HFD2_k127_8593344_1 PilZ domain - - - 0.000000000159 68.0
HFD2_k127_8593344_2 Glutaredoxin K03676 - - 0.0000000005694 61.0
HFD2_k127_8593344_3 WLM domain - GO:0000731,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006508,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0018130,GO:0019438,GO:0019538,GO:0019985,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070011,GO:0071704,GO:0071897,GO:0090304,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.000124 51.0
HFD2_k127_8605011_0 Belongs to the GPI family K01810 GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 4.062e-270 841.0
HFD2_k127_8605011_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 2.197e-241 758.0
HFD2_k127_8605011_2 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00819,K00821 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.11,2.6.1.13,2.6.1.17 3.126e-196 621.0
HFD2_k127_8605011_3 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006126 282.0
HFD2_k127_8605011_4 PFAM OsmC family protein - - - 0.000000000000000000006551 93.0
HFD2_k127_8605773_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 497.0
HFD2_k127_8605773_1 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 375.0
HFD2_k127_8605773_2 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000001965 214.0
HFD2_k127_8605773_3 Transglycosylase - - - 0.00000000000000000000000000000000000000001112 161.0
HFD2_k127_8605773_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000008835 102.0
HFD2_k127_8622493_0 Dystroglycan-type cadherin-like domains. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 336.0
HFD2_k127_8622493_1 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001115 293.0
HFD2_k127_8640382_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001235 290.0
HFD2_k127_8640382_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000002552 217.0
HFD2_k127_8640382_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000005283 146.0
HFD2_k127_8640382_3 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000002966 137.0
HFD2_k127_8640382_4 Domain of unknown function (DUF2520) - - - 0.0000000000000000000000000000004504 135.0
HFD2_k127_8640382_5 Domain of unknown function (DUF4388) - - - 0.00000000000000000001174 100.0
HFD2_k127_8653382_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.000000000000000000000000000000000000000000000078 184.0
HFD2_k127_8653382_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.00000000000000556 84.0
HFD2_k127_8653382_2 Outer membrane efflux protein - - - 0.0000000342 56.0
HFD2_k127_8661242_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 419.0
HFD2_k127_8661242_1 PilZ domain - - - 0.00001526 54.0
HFD2_k127_868289_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 310.0
HFD2_k127_868289_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000005061 166.0
HFD2_k127_868289_2 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000009919 175.0
HFD2_k127_8701542_0 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000009853 247.0
HFD2_k127_8701542_1 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000000000000000000003207 178.0
HFD2_k127_8701542_2 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000004335 131.0
HFD2_k127_8710804_0 Glutamine synthetase, beta-Grasp domain K01915 - 6.3.1.2 1.718e-238 744.0
HFD2_k127_8710804_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000208 117.0
HFD2_k127_8711827_0 FtsX-like permease family K02004 - - 4.186e-253 808.0
HFD2_k127_8711827_1 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 288.0
HFD2_k127_8711827_2 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000006279 214.0
HFD2_k127_8717863_0 Zinc metalloprotease (Elastase) K20274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 400.0
HFD2_k127_8717863_1 Proprotein convertase P-domain - - - 0.00002542 58.0
HFD2_k127_8727248_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 558.0
HFD2_k127_8727248_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 321.0
HFD2_k127_8727248_2 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000008253 194.0
HFD2_k127_8742532_0 signal sequence binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 422.0
HFD2_k127_8742532_1 diguanylate cyclase activity K02000,K04767,K05847,K07168,K09137 - 3.6.3.32 0.000000000000000004715 90.0
HFD2_k127_8742532_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530,K04764 - - 0.00000002521 64.0
HFD2_k127_874698_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007328 464.0
HFD2_k127_874698_1 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.000000000000000000000000000000000000000021 157.0
HFD2_k127_882753_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000009484 194.0
HFD2_k127_882753_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000002994 59.0
HFD2_k127_882753_2 AsmA family K07289,K07290 - - 0.000000005043 67.0
HFD2_k127_882753_3 ubiquitin K02927,K07451,K13735 - - 0.00002625 57.0
HFD2_k127_882753_4 Lysophospholipase L1 and related esterases - GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0016042,GO:0044238,GO:0071704,GO:1901575 - 0.0003159 54.0
HFD2_k127_889719_0 NADH dehydrogenase K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 344.0
HFD2_k127_889719_1 Proton-conducting membrane transporter K12137,K15828 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005844 282.0
HFD2_k127_922359_0 H( )-stimulated, divalent metal cation uptake system K03322 - - 7.428e-208 666.0
HFD2_k127_922359_1 PFAM Integral membrane protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009348 352.0
HFD2_k127_922359_2 Polymer-forming cytoskeletal - - - 0.00000000000000008751 91.0
HFD2_k127_922359_3 Putative metal-binding motif - - - 0.00002038 57.0
HFD2_k127_922359_4 cellulose binding K12132 - 2.7.11.1 0.00009971 50.0
HFD2_k127_928860_0 Tricorn protease PDZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 603.0
HFD2_k127_928860_1 cell shape determining protein MreB K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 430.0
HFD2_k127_957655_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 527.0
HFD2_k127_957655_1 4Fe-4S dicluster domain K16887 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001139 281.0
HFD2_k127_957655_2 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000001354 217.0
HFD2_k127_957655_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.00000000000000000008817 98.0
HFD2_k127_960641_0 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000001169 250.0
HFD2_k127_960641_1 Peptidase M56 - - - 0.0000000000000000000000000000000000000000135 172.0
HFD2_k127_960641_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000003517 51.0
HFD2_k127_963366_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000001102 61.0
HFD2_k127_965653_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006735 520.0
HFD2_k127_965653_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 315.0
HFD2_k127_984904_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 329.0
HFD2_k127_984904_1 Putative regulatory protein - - - 0.000000000000000000000000000009496 120.0
HFD2_k127_984904_2 - - - - 0.000007818 56.0
HFD2_k127_988997_0 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 530.0
HFD2_k127_988997_1 - - - - 0.0000000000000000000000000000000000000000000000000000000009078 215.0