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Overview

ID MAG01650
Name HFD2_bin.39
Sample SMP0044
Taxonomy
Kingdom Bacteria
Phylum Methylomirabilota
Class Methylomirabilia
Order Rokubacteriales
Family CSP1-6
Genus
Species
Assembly information
Completeness (%) 81.09
Contamination (%) 4.4
GC content (%) 70.0
N50 (bp) 30,540
Genome size (bp) 4,734,090

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4276

Gene name Description KEGG GOs EC E-value Score Sequence
HFD2_k127_1020376_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1276.0
HFD2_k127_1020376_1 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 8.983e-204 656.0
HFD2_k127_1020376_10 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 408.0
HFD2_k127_1020376_11 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 410.0
HFD2_k127_1020376_12 PFAM Alcohol dehydrogenase zinc-binding domain protein K00001,K07119 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 384.0
HFD2_k127_1020376_13 fad dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 386.0
HFD2_k127_1020376_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 327.0
HFD2_k127_1020376_15 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01872,K07050 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007644 312.0
HFD2_k127_1020376_16 Thioesterase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 299.0
HFD2_k127_1020376_17 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 302.0
HFD2_k127_1020376_18 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001036 291.0
HFD2_k127_1020376_19 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001937 295.0
HFD2_k127_1020376_2 PFAM Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 630.0
HFD2_k127_1020376_20 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007744 275.0
HFD2_k127_1020376_21 phosphorelay sensor kinase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000003254 261.0
HFD2_k127_1020376_22 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000004015 207.0
HFD2_k127_1020376_23 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000365 197.0
HFD2_k127_1020376_24 PFAM Phosphoglycerate mutase - - - 0.0000000000000000000000000000000000000000000000004265 184.0
HFD2_k127_1020376_25 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000003047 183.0
HFD2_k127_1020376_26 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000000000000000000000005563 170.0
HFD2_k127_1020376_27 - - - - 0.00000000000000000000000000000000000000002857 171.0
HFD2_k127_1020376_28 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000003906 141.0
HFD2_k127_1020376_29 Alpha/beta hydrolase family - - - 0.00000000000000000000002009 104.0
HFD2_k127_1020376_3 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483 - 1.14.14.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 527.0
HFD2_k127_1020376_30 SNARE-like domain protein - - - 0.000000000000000000001103 105.0
HFD2_k127_1020376_31 Haloacid dehalogenase-like hydrolase K07025,K18569 - - 0.000000000000001637 85.0
HFD2_k127_1020376_32 Methyltransferase type 12 - - - 0.00001761 57.0
HFD2_k127_1020376_4 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 449.0
HFD2_k127_1020376_5 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 448.0
HFD2_k127_1020376_6 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 423.0
HFD2_k127_1020376_7 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 414.0
HFD2_k127_1020376_8 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 416.0
HFD2_k127_1020376_9 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 419.0
HFD2_k127_1050304_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009897 550.0
HFD2_k127_1050304_1 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 455.0
HFD2_k127_1050304_2 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 357.0
HFD2_k127_1050304_3 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 327.0
HFD2_k127_1050304_4 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006421 278.0
HFD2_k127_1050304_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001491 257.0
HFD2_k127_1050304_6 Uncharacterised nucleotidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002725 249.0
HFD2_k127_1050304_7 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001692 243.0
HFD2_k127_1050304_8 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000001795 188.0
HFD2_k127_1075345_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.452e-271 857.0
HFD2_k127_1075345_1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 1.079e-202 644.0
HFD2_k127_1075345_10 - - - - 0.00000000000000000000000000008754 125.0
HFD2_k127_1075345_11 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000003992 100.0
HFD2_k127_1075345_12 Alpha/beta hydrolase family - - - 0.00000000000001168 78.0
HFD2_k127_1075345_13 Serine aminopeptidase, S33 - - - 0.0000000000001597 72.0
HFD2_k127_1075345_14 BlaR1 peptidase M56 - - - 0.0001439 56.0
HFD2_k127_1075345_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 3.162e-199 629.0
HFD2_k127_1075345_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 378.0
HFD2_k127_1075345_4 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 339.0
HFD2_k127_1075345_5 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001044 280.0
HFD2_k127_1075345_6 Nitronate monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001453 262.0
HFD2_k127_1075345_7 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000000000000000000000000004271 186.0
HFD2_k127_1075345_8 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000002515 143.0
HFD2_k127_1075345_9 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000001231 122.0
HFD2_k127_1079908_0 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 533.0
HFD2_k127_1079908_1 Acyl- CoA dehydrogenase type 2 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 400.0
HFD2_k127_1079908_10 Glyoxalase-like domain K04750 - - 0.00000000000000000000003441 113.0
HFD2_k127_1079908_11 - - - - 0.000000000000000002489 86.0
HFD2_k127_1079908_2 SAICAR synthetase K01923,K01945 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008949 355.0
HFD2_k127_1079908_3 RsbT co-antagonist protein rsbRD N-terminal domain K17763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 334.0
HFD2_k127_1079908_4 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K18702 - 2.8.3.16,2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000798 306.0
HFD2_k127_1079908_5 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000005388 245.0
HFD2_k127_1079908_6 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000001537 244.0
HFD2_k127_1079908_7 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000004802 217.0
HFD2_k127_1079908_8 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000006039 138.0
HFD2_k127_1079908_9 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000002809 122.0
HFD2_k127_117436_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 392.0
HFD2_k127_117436_2 Lanthionine synthetase C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 322.0
HFD2_k127_117436_3 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006909 253.0
HFD2_k127_117436_4 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000003807 228.0
HFD2_k127_117436_5 extracellular solute-binding protein, family 5 - - - 0.0000000000000000000000000000000000000000000000000001392 212.0
HFD2_k127_117436_6 lipoprotein biosynthetic process - - - 0.00000000000000000000009113 109.0
HFD2_k127_1242692_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 421.0
HFD2_k127_1242692_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 406.0
HFD2_k127_1242692_2 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000001184 246.0
HFD2_k127_1242692_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000002383 118.0
HFD2_k127_1242692_4 PFAM S23 ribosomal protein - - - 0.00000000000000000000000000004541 120.0
HFD2_k127_1242692_5 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.00004116 48.0
HFD2_k127_1299659_0 PFAM D-galactarate dehydratase Altronate hydrolase K01685 - 4.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007796 590.0
HFD2_k127_1299659_1 OST-HTH/LOTUS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 376.0
HFD2_k127_1299659_10 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000281 269.0
HFD2_k127_1299659_11 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004191 266.0
HFD2_k127_1299659_12 Poly A polymerase head domain K00970,K00974,K07276,K19545 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000003828 278.0
HFD2_k127_1299659_13 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000001366 245.0
HFD2_k127_1299659_14 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000004329 227.0
HFD2_k127_1299659_15 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000166 232.0
HFD2_k127_1299659_16 PFAM FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000004393 198.0
HFD2_k127_1299659_17 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000003161 184.0
HFD2_k127_1299659_18 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000001394 172.0
HFD2_k127_1299659_19 TrkA-N domain K03455,K10716 - - 0.00000000000000000000000000000000000000000006735 164.0
HFD2_k127_1299659_2 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 388.0
HFD2_k127_1299659_20 Thioredoxin - - - 0.0000000000000000000000000000000001832 136.0
HFD2_k127_1299659_21 Cytochrome C biogenesis protein - - - 0.000000000000000000000000000000109 126.0
HFD2_k127_1299659_22 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000000000643 119.0
HFD2_k127_1299659_23 - - - - 0.00000000000000008775 91.0
HFD2_k127_1299659_24 ATP-dependent Clp protease adaptor protein ClpS - - - 0.0000000000005001 74.0
HFD2_k127_1299659_25 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000001769 74.0
HFD2_k127_1299659_26 Redoxin - - - 0.000000002863 61.0
HFD2_k127_1299659_27 - - - - 0.000007822 48.0
HFD2_k127_1299659_28 Polysaccharide deacetylase - - - 0.000564 51.0
HFD2_k127_1299659_3 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 357.0
HFD2_k127_1299659_4 Belongs to the ABC transporter superfamily K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008273 351.0
HFD2_k127_1299659_5 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 323.0
HFD2_k127_1299659_6 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 315.0
HFD2_k127_1299659_7 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369,K13890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 293.0
HFD2_k127_1299659_8 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 289.0
HFD2_k127_1299659_9 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009224 287.0
HFD2_k127_1348799_0 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 521.0
HFD2_k127_1348799_1 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001986 289.0
HFD2_k127_1348799_2 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001558 278.0
HFD2_k127_1348799_3 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002602 268.0
HFD2_k127_1348799_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000008055 250.0
HFD2_k127_1348799_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000002314 104.0
HFD2_k127_1348799_6 Domain of unknown function (DUF4340) - - - 0.0000000000000000002194 99.0
HFD2_k127_1383109_0 Short-chain dehydrogenase reductase (SDR) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 321.0
HFD2_k127_1383109_1 alpha/beta hydrolase fold K01066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 295.0
HFD2_k127_1388694_0 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 354.0
HFD2_k127_1388694_1 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 346.0
HFD2_k127_1388694_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000002536 190.0
HFD2_k127_1410757_0 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000357 207.0
HFD2_k127_1469847_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 586.0
HFD2_k127_1469847_1 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 420.0
HFD2_k127_1469847_2 Peptidase m28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 297.0
HFD2_k127_14873_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 1.282e-304 948.0
HFD2_k127_14873_1 Phytanoyl-CoA dioxygenase (PhyH) K21195 - 1.14.11.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005126 329.0
HFD2_k127_14873_2 hydrolase of alkaline phosphatase superfamily K07014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006711 338.0
HFD2_k127_14873_3 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002922 246.0
HFD2_k127_14873_4 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.000000000000000000000000000000000000000000000000000000000000001433 237.0
HFD2_k127_14873_5 60Kd inner membrane protein - - - 0.00000000000000000000000000003499 137.0
HFD2_k127_14873_6 - - - - 0.00005155 48.0
HFD2_k127_1530062_0 ABC transporter transmembrane region - - - 0.0 1391.0
HFD2_k127_1530062_1 Isocitrate/isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 537.0
HFD2_k127_1530062_2 FMN-dependent dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 461.0
HFD2_k127_1530062_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 369.0
HFD2_k127_1530062_4 clavaminate synthase activity K00471 - 1.14.11.1 0.0000000000000000000000000000000001271 139.0
HFD2_k127_153511_0 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 1.038e-305 950.0
HFD2_k127_153511_1 PFAM Sulfatase K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 586.0
HFD2_k127_153511_10 transport system periplasmic component K21395 - - 0.00000000000000000000000000000000000000000000004336 184.0
HFD2_k127_153511_11 Cysteine-rich motif following a subset of SET domains K07117 - - 0.000000000000000000000000000000000000000001789 172.0
HFD2_k127_153511_12 - - - - 0.0000000000000000000000000000000000000003387 156.0
HFD2_k127_153511_13 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000006805 124.0
HFD2_k127_153511_14 Type II secretory pathway, component ExeA K02450 - - 0.0000000000000000000000001228 122.0
HFD2_k127_153511_15 Protein of unknown function (DUF3175) - - - 0.000000000000000000000000127 113.0
HFD2_k127_153511_16 hyperosmotic response - - - 0.00000000000000000000001017 110.0
HFD2_k127_153511_17 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000003358 89.0
HFD2_k127_153511_18 spore germination - - - 0.000000000002422 79.0
HFD2_k127_153511_2 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009777 405.0
HFD2_k127_153511_3 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 394.0
HFD2_k127_153511_4 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001376 276.0
HFD2_k127_153511_5 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002558 271.0
HFD2_k127_153511_6 Belongs to the Nudix hydrolase family K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000003891 262.0
HFD2_k127_153511_7 mannose-ethanolamine phosphotransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000003699 241.0
HFD2_k127_153511_8 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000001113 223.0
HFD2_k127_153511_9 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000000000001384 177.0
HFD2_k127_1613699_0 FAD dependent oxidoreductase - - - 1.533e-199 632.0
HFD2_k127_1613699_1 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 438.0
HFD2_k127_173168_0 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007631 544.0
HFD2_k127_173168_1 Belongs to the PstS family K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 393.0
HFD2_k127_173168_10 Serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 0.00000000000000000000000000002153 119.0
HFD2_k127_173168_11 Bacterial protein of unknown function (DUF839) K07093 - - 0.0004156 47.0
HFD2_k127_173168_2 MmgE/PrpD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008342 391.0
HFD2_k127_173168_3 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 379.0
HFD2_k127_173168_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 371.0
HFD2_k127_173168_5 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 370.0
HFD2_k127_173168_6 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 365.0
HFD2_k127_173168_7 Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 314.0
HFD2_k127_173168_8 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007031 269.0
HFD2_k127_173168_9 PFAM response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000000000000000000000000000000000000000000000000005239 239.0
HFD2_k127_1757503_0 transferase activity, transferring glycosyl groups K12996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 472.0
HFD2_k127_1757503_1 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005689 342.0
HFD2_k127_1757503_2 Sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 310.0
HFD2_k127_1757503_3 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000005738 237.0
HFD2_k127_1757503_4 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000002117 235.0
HFD2_k127_1757503_5 Methionine biosynthesis protein MetW K18827 - 2.1.1.294,2.7.1.181 0.0000000000000000000000000000000000000000000000000000000000002237 222.0
HFD2_k127_1757503_6 - - - - 0.000000000000000000000000000000000000000000000000000000003298 213.0
HFD2_k127_1757503_7 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000007904 113.0
HFD2_k127_1757503_8 Tetratricopeptide repeat - - - 0.000000000000001471 91.0
HFD2_k127_1757503_9 SMART Tetratricopeptide - - - 0.000000000000003763 82.0
HFD2_k127_1766840_0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 0.0 1043.0
HFD2_k127_1766840_1 synthase K00705,K06044 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576 2.4.1.25,5.4.99.15 8.102e-295 935.0
HFD2_k127_1766840_10 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 578.0
HFD2_k127_1766840_11 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 531.0
HFD2_k127_1766840_12 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 513.0
HFD2_k127_1766840_13 acyl-CoA transferases carnitine dehydratase K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 426.0
HFD2_k127_1766840_14 glycogen (starch) synthase activity K16148 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 402.0
HFD2_k127_1766840_15 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 386.0
HFD2_k127_1766840_16 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000975 377.0
HFD2_k127_1766840_17 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 351.0
HFD2_k127_1766840_18 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 332.0
HFD2_k127_1766840_19 N-terminal half of MaoC dehydratase K09709 - 4.2.1.153 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 325.0
HFD2_k127_1766840_2 Maltogenic Amylase, C-terminal domain K05343 - 3.2.1.1,5.4.99.16 2.095e-282 875.0
HFD2_k127_1766840_20 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 320.0
HFD2_k127_1766840_21 Phosphotransferase enzyme family K00700,K05343,K16146 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016310,GO:0034637,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046835,GO:0071704,GO:0071944,GO:1901576 2.4.1.18,2.7.1.175,3.2.1.1,5.4.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 312.0
HFD2_k127_1766840_22 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 297.0
HFD2_k127_1766840_23 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006664 296.0
HFD2_k127_1766840_24 branched-chain amino acid ABC transporter ATP-binding protein K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002518 276.0
HFD2_k127_1766840_25 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008448 264.0
HFD2_k127_1766840_26 Glycosyl transferase family 2 K21349 - 2.4.1.268 0.000000000000000000000000000000000000000000000000000000000000000199 236.0
HFD2_k127_1766840_27 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000002969 238.0
HFD2_k127_1766840_28 PFAM Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000002791 226.0
HFD2_k127_1766840_29 transmembrane transport - - - 0.0000000000000000000000000000000000000000000000000000000006404 209.0
HFD2_k127_1766840_3 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 2.238e-232 777.0
HFD2_k127_1766840_30 Belongs to the short-chain dehydrogenases reductases (SDR) family K03366 - 1.1.1.304,1.1.1.76 0.0000000000000000000000000000000000000000000000000000004459 203.0
HFD2_k127_1766840_31 Conserved protein of dim6 ntab family - - - 0.000000000000000000000000000000000000000000000000009392 201.0
HFD2_k127_1766840_32 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000002467 185.0
HFD2_k127_1766840_33 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000003604 173.0
HFD2_k127_1766840_34 ChrR Cupin-like domain - - - 0.00000000000000000000000000000000000000004376 159.0
HFD2_k127_1766840_35 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000001284 168.0
HFD2_k127_1766840_36 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000541 166.0
HFD2_k127_1766840_37 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.000000000000000000000000000000000000002665 151.0
HFD2_k127_1766840_38 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000007245 107.0
HFD2_k127_1766840_39 Thioredoxin - - - 0.0000000000000000000001346 105.0
HFD2_k127_1766840_4 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K03520 - 1.2.5.3 7.159e-232 743.0
HFD2_k127_1766840_40 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.000000000000000000003214 102.0
HFD2_k127_1766840_41 PFAM DinB family protein - - - 0.0000000000000000002222 99.0
HFD2_k127_1766840_42 COG0457 FOG TPR repeat - - - 0.0000000000000001885 93.0
HFD2_k127_1766840_43 Tetratricopeptide repeat - - - 0.00000832 59.0
HFD2_k127_1766840_5 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 1.792e-231 730.0
HFD2_k127_1766840_6 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 4.112e-228 736.0
HFD2_k127_1766840_7 Alpha amylase, catalytic domain K01236 - 3.2.1.141 3.378e-211 705.0
HFD2_k127_1766840_8 PFAM amidohydrolase K07045 - - 3.025e-207 649.0
HFD2_k127_1766840_9 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 610.0
HFD2_k127_1768955_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 400.0
HFD2_k127_1768955_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 373.0
HFD2_k127_1768955_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006471 346.0
HFD2_k127_1768955_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 346.0
HFD2_k127_1768955_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 334.0
HFD2_k127_1768955_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001317 293.0
HFD2_k127_1768955_6 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000003591 239.0
HFD2_k127_1768955_7 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000004594 219.0
HFD2_k127_1768955_8 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000002755 184.0
HFD2_k127_1770430_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 581.0
HFD2_k127_1770430_1 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 460.0
HFD2_k127_1770430_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000002864 240.0
HFD2_k127_1770430_3 Peptidase family M28 - - - 0.000000000000000000000007394 106.0
HFD2_k127_1774777_0 aldo keto reductase K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 349.0
HFD2_k127_1774777_1 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000005245 195.0
HFD2_k127_1774777_2 Aldo/keto reductase family - - - 0.00000000000003784 83.0
HFD2_k127_1774777_3 Redoxin - - - 0.0000958 51.0
HFD2_k127_1788870_0 symporter activity K03307 - - 2.203e-268 837.0
HFD2_k127_1788870_1 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 587.0
HFD2_k127_1788870_2 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000005194 232.0
HFD2_k127_1837109_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 1.086e-229 722.0
HFD2_k127_1837109_1 3-demethylubiquinone-9 3-O-methyltransferase activity K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 460.0
HFD2_k127_1837109_10 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.0000000000000000000000000000000002205 151.0
HFD2_k127_1837109_11 Rhodanese Homology Domain - - - 0.0000000000000000000002997 101.0
HFD2_k127_1837109_12 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000004091 106.0
HFD2_k127_1837109_13 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00992 - 2.7.7.99 0.0000000001472 73.0
HFD2_k127_1837109_14 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000007653 50.0
HFD2_k127_1837109_15 of the major facilitator superfamily K08151 - - 0.0001217 54.0
HFD2_k127_1837109_2 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 389.0
HFD2_k127_1837109_3 Copper resistance K07245 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 337.0
HFD2_k127_1837109_4 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004871 279.0
HFD2_k127_1837109_5 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001392 278.0
HFD2_k127_1837109_6 TOBE domain K02010,K02052,K10112,K10235 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000004717 225.0
HFD2_k127_1837109_7 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000005345 198.0
HFD2_k127_1837109_8 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000000000685 179.0
HFD2_k127_1837109_9 Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000007755 177.0
HFD2_k127_1842166_0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000000000000000000000000000001766 213.0
HFD2_k127_1842166_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000003407 165.0
HFD2_k127_1842166_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000000000000000000007576 165.0
HFD2_k127_1842166_3 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000001188 154.0
HFD2_k127_1842166_4 Domain of unknown function (DUF4184) - - - 0.00000000000000000000000000000000000001142 156.0
HFD2_k127_1842166_5 transferase activity, transferring acyl groups K03824 - - 0.0000000000000000000000000000000001436 143.0
HFD2_k127_1842166_6 - - - - 0.00000000000000005312 94.0
HFD2_k127_1842166_8 HxlR-like helix-turn-helix - - - 0.00000009579 63.0
HFD2_k127_1842166_9 DoxX-like family - - - 0.000008779 54.0
HFD2_k127_1906399_0 ABC transporter K02471 - - 7.165e-275 854.0
HFD2_k127_1906399_1 Dehydrogenase E1 component K00164 - 1.2.4.2 3.552e-274 897.0
HFD2_k127_1906399_10 SET domain K07117 - - 0.00000000000000000000000000000000000000000000000003499 186.0
HFD2_k127_1906399_11 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000001371 175.0
HFD2_k127_1906399_12 metal-binding integral membrane protein - - - 0.00000000000000000000000000000000000000000002173 171.0
HFD2_k127_1906399_13 - - - - 0.0000000000000000000000825 112.0
HFD2_k127_1906399_15 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - GO:0000166,GO:0000959,GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003723,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006970,GO:0007275,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009414,GO:0009415,GO:0009451,GO:0009628,GO:0009631,GO:0009651,GO:0009791,GO:0009845,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031554,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034336,GO:0034641,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043242,GO:0043244,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0060567,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090351,GO:0097159,GO:0097367,GO:1900864,GO:1901265,GO:1901360,GO:1901363,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000128 99.0
HFD2_k127_1906399_16 Patatin-like phospholipase K07001 - - 0.000001216 61.0
HFD2_k127_1906399_17 - - - - 0.000001734 60.0
HFD2_k127_1906399_2 unfolded protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 553.0
HFD2_k127_1906399_3 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 533.0
HFD2_k127_1906399_4 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 426.0
HFD2_k127_1906399_5 PFAM SMP-30 Gluconolaconase LRE domain protein K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 321.0
HFD2_k127_1906399_6 Methionine synthase K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008806 296.0
HFD2_k127_1906399_7 5-formyltetrahydrofolate cycloligase K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000002402 250.0
HFD2_k127_1906399_8 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000000000000000000000000003686 220.0
HFD2_k127_1906399_9 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000003618 211.0
HFD2_k127_1910668_0 helix_turn_helix gluconate operon transcriptional repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 473.0
HFD2_k127_1910668_1 enterobactin catabolic process K07214 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001996 255.0
HFD2_k127_1910668_2 DinB family - - - 0.0000000000000000000000000000000000000000000000007716 181.0
HFD2_k127_1910668_3 - - - - 0.000000000000000000000000002462 113.0
HFD2_k127_1910668_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000003096 73.0
HFD2_k127_1934188_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 425.0
HFD2_k127_1934188_1 Transposase IS116/IS110/IS902 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 440.0
HFD2_k127_1934188_2 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 - 4.1.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 348.0
HFD2_k127_1934188_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01684 - 4.2.1.6 0.00000000000000000000000000000000000000000000002553 176.0
HFD2_k127_1968148_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1277.0
HFD2_k127_1968148_1 Beta-lactamase - - - 8.035e-205 663.0
HFD2_k127_1968148_10 COGs COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 345.0
HFD2_k127_1968148_11 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 323.0
HFD2_k127_1968148_12 of the alpha beta superfamily K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 289.0
HFD2_k127_1968148_13 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002073 286.0
HFD2_k127_1968148_14 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002223 299.0
HFD2_k127_1968148_15 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004962 275.0
HFD2_k127_1968148_16 Uncharacterized conserved protein (DUF2075) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004966 264.0
HFD2_k127_1968148_17 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004204 252.0
HFD2_k127_1968148_18 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000001043 227.0
HFD2_k127_1968148_19 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000002074 214.0
HFD2_k127_1968148_2 Belongs to the UbiD family K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 608.0
HFD2_k127_1968148_20 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.0000000000000000000000000000000000000000000000000000002282 209.0
HFD2_k127_1968148_21 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000001111 199.0
HFD2_k127_1968148_22 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000007297 165.0
HFD2_k127_1968148_23 - - - - 0.0000000000000000000000000000000000009765 145.0
HFD2_k127_1968148_24 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000008086 147.0
HFD2_k127_1968148_25 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000001847 135.0
HFD2_k127_1968148_26 mRNA binding - - - 0.0000000000000000000000000002799 115.0
HFD2_k127_1968148_27 Predicted permease - - - 0.00000000000000000000000006811 115.0
HFD2_k127_1968148_28 Thioredoxin domain - - - 0.000000000000000000000001083 109.0
HFD2_k127_1968148_29 Helix-turn-helix domain - - - 0.00000000000000000001453 94.0
HFD2_k127_1968148_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 557.0
HFD2_k127_1968148_30 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000008997 94.0
HFD2_k127_1968148_31 Thioredoxin domain - - - 0.000000000000000001759 87.0
HFD2_k127_1968148_32 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.000000000000002933 83.0
HFD2_k127_1968148_33 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000004286 78.0
HFD2_k127_1968148_34 conserved protein, contains double-stranded beta-helix domain - - - 0.000000000003967 73.0
HFD2_k127_1968148_35 Protein of unknown function, DUF393 - - - 0.00000000003089 70.0
HFD2_k127_1968148_36 Luciferase-like monooxygenase - - - 0.0000000003246 62.0
HFD2_k127_1968148_37 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.0000008885 59.0
HFD2_k127_1968148_38 Phage integrase, N-terminal SAM-like domain K03733 - - 0.00004033 54.0
HFD2_k127_1968148_39 DinB superfamily - - - 0.0001242 52.0
HFD2_k127_1968148_4 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 487.0
HFD2_k127_1968148_5 Belongs to the UbiD family K16874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 448.0
HFD2_k127_1968148_6 Pyruvate kinase, alpha/beta domain K00873 GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 415.0
HFD2_k127_1968148_7 Thiamine pyrophosphate enzyme, central domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 379.0
HFD2_k127_1968148_8 Putative glycosyl hydrolase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000603 376.0
HFD2_k127_1968148_9 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 369.0
HFD2_k127_1979870_0 DegT/DnrJ/EryC1/StrS aminotransferase family K04127 - 5.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 491.0
HFD2_k127_1979870_1 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 441.0
HFD2_k127_1979870_10 HpcH/HpaI aldolase/citrate lyase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 316.0
HFD2_k127_1979870_11 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 295.0
HFD2_k127_1979870_12 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000005634 243.0
HFD2_k127_1979870_13 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000005428 233.0
HFD2_k127_1979870_14 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000000000353 235.0
HFD2_k127_1979870_15 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000001844 240.0
HFD2_k127_1979870_16 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000001081 219.0
HFD2_k127_1979870_17 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000005839 177.0
HFD2_k127_1979870_18 NIPSNAP - - - 0.00000000000000000000000000000000000000006919 173.0
HFD2_k127_1979870_19 hydrolases or acyltransferases alpha beta hydrolase superfamily - - - 0.00000000000000000000000000000000005295 142.0
HFD2_k127_1979870_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 435.0
HFD2_k127_1979870_20 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000007608 138.0
HFD2_k127_1979870_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 437.0
HFD2_k127_1979870_4 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 400.0
HFD2_k127_1979870_5 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 375.0
HFD2_k127_1979870_6 Oxidoreductase family, NAD-binding Rossmann fold K10219 - 1.1.1.312 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 354.0
HFD2_k127_1979870_7 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008273 362.0
HFD2_k127_1979870_8 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 329.0
HFD2_k127_1979870_9 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 327.0
HFD2_k127_1980657_0 alpha,alpha-trehalase activity K01194,K03931 GO:0003674,GO:0003824,GO:0004553,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015926,GO:0016787,GO:0016798,GO:0033554,GO:0050896,GO:0051716 3.2.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 344.0
HFD2_k127_1980657_1 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000001638 146.0
HFD2_k127_1985168_0 PFAM AMP-dependent synthetase and ligase - - - 4.259e-224 707.0
HFD2_k127_1985168_1 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain - - - 9.615e-210 676.0
HFD2_k127_1985168_10 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 458.0
HFD2_k127_1985168_11 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 444.0
HFD2_k127_1985168_12 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 370.0
HFD2_k127_1985168_13 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 387.0
HFD2_k127_1985168_14 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 356.0
HFD2_k127_1985168_15 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 353.0
HFD2_k127_1985168_16 TOBE domain K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 350.0
HFD2_k127_1985168_17 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 351.0
HFD2_k127_1985168_18 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 336.0
HFD2_k127_1985168_19 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008173 326.0
HFD2_k127_1985168_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 3.701e-205 648.0
HFD2_k127_1985168_20 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 329.0
HFD2_k127_1985168_21 Belongs to the UbiD family K16874 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 331.0
HFD2_k127_1985168_22 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 333.0
HFD2_k127_1985168_23 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006803 328.0
HFD2_k127_1985168_24 MmgE PrpD family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 325.0
HFD2_k127_1985168_25 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006212 299.0
HFD2_k127_1985168_26 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 293.0
HFD2_k127_1985168_27 PFAM Hydantoinase B oxoprolinase K01469,K01474 - 3.5.2.14,3.5.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 291.0
HFD2_k127_1985168_28 Protein of unknown function (DUF3750) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003622 279.0
HFD2_k127_1985168_29 ABC-type Fe3 transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002581 282.0
HFD2_k127_1985168_3 peptidase, M20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 609.0
HFD2_k127_1985168_30 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005573 274.0
HFD2_k127_1985168_31 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005054 242.0
HFD2_k127_1985168_32 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000000008922 238.0
HFD2_k127_1985168_33 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000000000000000000000000001091 233.0
HFD2_k127_1985168_34 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000006818 218.0
HFD2_k127_1985168_35 4-phosphoerythronate dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000004685 222.0
HFD2_k127_1985168_36 PFAM SpoU rRNA Methylase family - - - 0.00000000000000000000000000000000000000000000000000000000002069 216.0
HFD2_k127_1985168_37 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000001611 224.0
HFD2_k127_1985168_38 ribonucleoside-diphosphate reductase activity K07735 - - 0.000000000000000000000000000000000000000000000000000005808 196.0
HFD2_k127_1985168_39 Cupin domain - - - 0.0000000000000000000000000000000000000000000000011 176.0
HFD2_k127_1985168_4 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 552.0
HFD2_k127_1985168_40 Family of unknown function (DUF1028) - - - 0.000000000000000000000000000000000000000000001106 175.0
HFD2_k127_1985168_41 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000002035 171.0
HFD2_k127_1985168_42 Proteasomal ATPase OB/ID domain K13527 - - 0.0000000000000000000000000000000000000008981 149.0
HFD2_k127_1985168_43 PFAM Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000005085 145.0
HFD2_k127_1985168_44 DinB family - - - 0.0000000000000000000000000000001641 142.0
HFD2_k127_1985168_45 EamA-like transporter family - - - 0.0000000000000000000000000000001901 137.0
HFD2_k127_1985168_46 - - - - 0.000000000000000000000003385 104.0
HFD2_k127_1985168_47 Belongs to the ompA family - - - 0.00000000000000000000009016 115.0
HFD2_k127_1985168_48 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.0000000000000000000014 102.0
HFD2_k127_1985168_49 membrane transporter protein K07090 - - 0.00000000000000000008722 100.0
HFD2_k127_1985168_5 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 537.0
HFD2_k127_1985168_50 Evidence 4 Homologs of previously reported genes of K21440 - - 0.0000000000000000001459 105.0
HFD2_k127_1985168_51 Glyoxalase bleomycin resistance protein dioxygenase K07104 - 1.13.11.2 0.0000000000000000005895 94.0
HFD2_k127_1985168_52 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000000001716 96.0
HFD2_k127_1985168_53 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0000000000000001348 86.0
HFD2_k127_1985168_54 Redoxin K03386 - 1.11.1.15 0.00000000000000112 80.0
HFD2_k127_1985168_55 Two component transcriptional regulator, winged helix family K07669,K07672 - - 0.000000000000007695 81.0
HFD2_k127_1985168_56 - - - - 0.0000000000005111 80.0
HFD2_k127_1985168_57 OmpA family - - - 0.00000000003358 73.0
HFD2_k127_1985168_58 Carboxymuconolactone decarboxylase family - - - 0.0000000001151 65.0
HFD2_k127_1985168_59 AAA domain K02450 - - 0.0000000001905 75.0
HFD2_k127_1985168_6 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008431 518.0
HFD2_k127_1985168_60 Thioredoxin - - - 0.000000007081 66.0
HFD2_k127_1985168_61 Uncharacterized protein conserved in bacteria (DUF2059) K09924 - - 0.0003401 51.0
HFD2_k127_1985168_7 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 516.0
HFD2_k127_1985168_8 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 521.0
HFD2_k127_1985168_9 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 477.0
HFD2_k127_1993232_0 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007862 397.0
HFD2_k127_1993232_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 303.0
HFD2_k127_1993232_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007684 253.0
HFD2_k127_1993232_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000008905 235.0
HFD2_k127_1993232_4 Belongs to the peptidase S1C family - - - 0.0000000000000000000000000000000000000000000000000000000267 214.0
HFD2_k127_1993232_5 response regulator K02485 - - 0.0000000000000000000000000000000000000000000000000000003701 220.0
HFD2_k127_1993232_6 Belongs to the CDS family - - - 0.00000000000000000000000000000000000000000000000003261 183.0
HFD2_k127_1993232_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000002256 136.0
HFD2_k127_1993289_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 404.0
HFD2_k127_1993289_1 Mut7-C ubiquitin K09122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000989 252.0
HFD2_k127_1993289_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000005145 123.0
HFD2_k127_1993289_3 Universal stress protein family - - - 0.000000000000000000005331 103.0
HFD2_k127_1993289_4 Homocysteine S-methyltransferase - - - 0.0000000000000000004899 93.0
HFD2_k127_1993289_5 Homocysteine S-methyltransferase - - - 0.0000000000000002363 83.0
HFD2_k127_1993289_6 zinc ion binding K06204 - - 0.00000000000404 71.0
HFD2_k127_2012834_0 Acyclic terpene utilisation family protein AtuA - - - 5.204e-201 640.0
HFD2_k127_2024964_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 613.0
HFD2_k127_2024964_1 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000005512 153.0
HFD2_k127_2024964_2 Thioesterase superfamily - - - 0.00000000000000000000000000000000157 136.0
HFD2_k127_2027786_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1102.0
HFD2_k127_2027786_1 benzoyl-CoA reductase K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 314.0
HFD2_k127_2027786_2 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001822 287.0
HFD2_k127_2027786_3 4Fe-4S binding domain K18362 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005468 261.0
HFD2_k127_2027786_4 dmso reductase anchor subunit - - - 0.000000000000000000000000000001019 132.0
HFD2_k127_2027786_5 Bacterial regulatory proteins, tetR family K09017 - - 0.000000000000000001138 95.0
HFD2_k127_2027786_6 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000001061 94.0
HFD2_k127_2043931_0 Amidohydrolase K07045 - - 1.224e-206 656.0
HFD2_k127_2043931_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 1.657e-204 663.0
HFD2_k127_2043931_10 DNA polymerase LigD polymerase domain K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 452.0
HFD2_k127_2043931_11 response regulator K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 433.0
HFD2_k127_2043931_12 PFAM Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 404.0
HFD2_k127_2043931_13 Sugar (and other) transporter K03446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 374.0
HFD2_k127_2043931_14 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 350.0
HFD2_k127_2043931_15 Binding-protein-dependent transport systems inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 336.0
HFD2_k127_2043931_16 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 295.0
HFD2_k127_2043931_17 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003267 259.0
HFD2_k127_2043931_18 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000164 215.0
HFD2_k127_2043931_19 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000001324 209.0
HFD2_k127_2043931_2 PFAM amidohydrolase K07045 - - 2.789e-198 623.0
HFD2_k127_2043931_20 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000004842 206.0
HFD2_k127_2043931_21 SnoaL-like polyketide cyclase K07255 - - 0.00000000000000000000000000000000000000000000000000007582 189.0
HFD2_k127_2043931_22 Ring hydroxylating beta subunit K18075 - 1.14.12.15 0.00000000000000000000000000000000000000000000000003914 190.0
HFD2_k127_2043931_23 Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000001222 188.0
HFD2_k127_2043931_24 - - - - 0.00000000000000000000000000000000000000000000001074 195.0
HFD2_k127_2043931_25 Histidine kinase K02668,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000006796 186.0
HFD2_k127_2043931_27 PFAM short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000001994 154.0
HFD2_k127_2043931_28 Hemerythrin hhe cation binding - - - 0.000000000000000000000000000000000005742 145.0
HFD2_k127_2043931_29 NIPSNAP - - - 0.000000000000000000000000000000003179 132.0
HFD2_k127_2043931_3 DNA polymerase beta thumb K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 555.0
HFD2_k127_2043931_30 DinB superfamily - - - 0.00000000000000000000001275 110.0
HFD2_k127_2043931_31 Two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.00000000000002197 85.0
HFD2_k127_2043931_4 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit K16319,K18074 - 1.14.12.1,1.14.12.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 527.0
HFD2_k127_2043931_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 517.0
HFD2_k127_2043931_6 Protein of unknown function (DUF917) K09703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 503.0
HFD2_k127_2043931_7 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000818 502.0
HFD2_k127_2043931_8 solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 474.0
HFD2_k127_2043931_9 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 486.0
HFD2_k127_2061046_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1106.0
HFD2_k127_2061046_1 Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 5.749e-223 698.0
HFD2_k127_2061046_10 COGs COG0569 K transport systems NAD-binding component K03499,K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003025 276.0
HFD2_k127_2061046_11 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004212 271.0
HFD2_k127_2061046_12 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000004799 246.0
HFD2_k127_2061046_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000001214 257.0
HFD2_k127_2061046_14 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000002559 198.0
HFD2_k127_2061046_15 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000003193 205.0
HFD2_k127_2061046_16 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000003039 202.0
HFD2_k127_2061046_17 ABC-type dipeptide transport system periplasmic component K02035 - - 0.00000000000000000000000000000000000000000000000001489 198.0
HFD2_k127_2061046_18 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000002447 173.0
HFD2_k127_2061046_19 alpha/beta hydrolase fold K01432 - 3.5.1.9 0.00000000000002327 82.0
HFD2_k127_2061046_2 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 521.0
HFD2_k127_2061046_3 Belongs to the peptidase M12A family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008453 512.0
HFD2_k127_2061046_4 von Willebrand factor, type A K02448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009246 520.0
HFD2_k127_2061046_5 Beta-lactamase K18372 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 494.0
HFD2_k127_2061046_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007047 390.0
HFD2_k127_2061046_7 Associated with various cellular activities K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008578 392.0
HFD2_k127_2061046_8 Cytochrome c K02305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 346.0
HFD2_k127_2061046_9 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 298.0
HFD2_k127_212425_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 2.132e-282 883.0
HFD2_k127_212425_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 2.82e-218 687.0
HFD2_k127_212425_10 His Kinase A (phosphoacceptor) domain K02484,K07636,K07768 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007202 503.0
HFD2_k127_212425_11 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 424.0
HFD2_k127_212425_12 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 409.0
HFD2_k127_212425_13 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 403.0
HFD2_k127_212425_14 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 404.0
HFD2_k127_212425_15 DegT/DnrJ/EryC1/StrS aminotransferase family K12452 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 398.0
HFD2_k127_212425_16 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 380.0
HFD2_k127_212425_17 carbamoyl transferase, NodU family K00612,K16035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 386.0
HFD2_k127_212425_18 TIGRFAM ABC transporter, urea, permease protein, UrtC K01998,K11961 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 370.0
HFD2_k127_212425_19 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 365.0
HFD2_k127_212425_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 2.221e-212 679.0
HFD2_k127_212425_20 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005069 319.0
HFD2_k127_212425_21 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 322.0
HFD2_k127_212425_22 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 331.0
HFD2_k127_212425_23 TIGRFAM ABC transporter, urea, ATP-binding protein, UrtD K11962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 307.0
HFD2_k127_212425_24 Two component transcriptional regulator, winged helix family K07658,K07668 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002065 274.0
HFD2_k127_212425_25 Urea ABC transporter ATP-binding protein K11963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006305 258.0
HFD2_k127_212425_26 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000003159 239.0
HFD2_k127_212425_27 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000001519 219.0
HFD2_k127_212425_28 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000005225 222.0
HFD2_k127_212425_29 PFAM NAD dependent epimerase dehydratase family K01710,K01784 - 4.2.1.46,5.1.3.2 0.000000000000000000000000000000000000000000000000005434 193.0
HFD2_k127_212425_3 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 8.03e-207 663.0
HFD2_k127_212425_30 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000001337 176.0
HFD2_k127_212425_31 Belongs to the urease beta subunit family K01427,K01428,K01429,K01430,K14048 GO:0003674,GO:0003824,GO:0006807,GO:0008150,GO:0008152,GO:0009039,GO:0009056,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016787,GO:0016810,GO:0016811,GO:0019627,GO:0034641,GO:0042221,GO:0043419,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071704,GO:0071941,GO:1901564,GO:1901565,GO:1901575 3.5.1.5 0.000000000000000000000000000000000000000000001266 166.0
HFD2_k127_212425_32 PFAM Urease beta subunit K01429,K14048 - 3.5.1.5 0.000000000000000000000000000000000000000002495 158.0
HFD2_k127_212425_33 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000007289 157.0
HFD2_k127_212425_34 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000002854 161.0
HFD2_k127_212425_35 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.000000000000000000000000000000000000003346 154.0
HFD2_k127_212425_36 ANTAR K07183,K22010 - - 0.00000000000000000000000000000000000002146 152.0
HFD2_k127_212425_37 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.00000000000000000000000000000000000984 151.0
HFD2_k127_212425_38 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.000000000000000000000000000000001815 139.0
HFD2_k127_212425_39 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.00000000000000000000000000000000705 139.0
HFD2_k127_212425_4 Ammonium Transporter Family K03320 - - 1.136e-198 630.0
HFD2_k127_212425_40 regulation of translation K03530 - - 0.000000000000000000000000000001062 127.0
HFD2_k127_212425_41 Phosphate acyltransferases - - - 0.00000000000000000000000000001035 130.0
HFD2_k127_212425_42 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.00000000000000000000000000002085 124.0
HFD2_k127_212425_43 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000008079 87.0
HFD2_k127_212425_44 redox protein regulator of disulfide bond formation K07397 - - 0.00000000000005675 74.0
HFD2_k127_212425_45 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000009635 80.0
HFD2_k127_212425_46 Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation K02485,K07315 GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0009893,GO:0010556,GO:0010604,GO:0016989,GO:0019219,GO:0019222,GO:0030162,GO:0031323,GO:0031325,GO:0031326,GO:0031647,GO:0031648,GO:0032268,GO:0032270,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0140110,GO:1903506,GO:2001141 3.1.3.3 0.0000000000188 70.0
HFD2_k127_212425_47 Two component, sigma54 specific, transcriptional regulator, Fis family K07712,K07714 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.0000000003909 69.0
HFD2_k127_212425_48 Lrp/AsnC ligand binding domain - - - 0.000000004164 65.0
HFD2_k127_212425_49 OsmC-like protein K06889,K07397 - - 0.00000001718 57.0
HFD2_k127_212425_5 NAD synthase K01916 - 6.3.1.5 5.294e-197 629.0
HFD2_k127_212425_50 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.00000003945 67.0
HFD2_k127_212425_51 Acetyltransferase (GNAT) domain - - - 0.0001912 50.0
HFD2_k127_212425_6 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 610.0
HFD2_k127_212425_7 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 526.0
HFD2_k127_212425_8 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 530.0
HFD2_k127_212425_9 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 513.0
HFD2_k127_21868_0 Carboxyl transferase domain - - - 3.767e-242 757.0
HFD2_k127_21868_1 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - - 8.741e-236 746.0
HFD2_k127_21868_10 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007037 387.0
HFD2_k127_21868_11 mandelate racemase muconate lactonizing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 334.0
HFD2_k127_21868_12 Nitroreductase family K10678 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 344.0
HFD2_k127_21868_13 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 314.0
HFD2_k127_21868_14 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007274 254.0
HFD2_k127_21868_15 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04101 - 1.13.11.8 0.0000000000000000000000000000000000000000000000000000000000000000000002339 252.0
HFD2_k127_21868_16 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000006348 256.0
HFD2_k127_21868_17 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.00000000000000000000000000000000000000000000000000000000000000001344 232.0
HFD2_k127_21868_18 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000008106 211.0
HFD2_k127_21868_19 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000004553 186.0
HFD2_k127_21868_2 COG3209 Rhs family protein - - - 2.219e-225 745.0
HFD2_k127_21868_20 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000000000000000001752 145.0
HFD2_k127_21868_21 Domain of unknown function (DUF1992) - - - 0.000000000000000000000000000001341 134.0
HFD2_k127_21868_22 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000374 129.0
HFD2_k127_21868_23 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000004968 114.0
HFD2_k127_21868_24 Peptidase family M28 - - - 0.000000000000000001569 99.0
HFD2_k127_21868_25 Aromatic-ring-opening dioxygenase LigAB, LigA subunit - - - 0.00000000000009435 75.0
HFD2_k127_21868_26 OsmC-like protein - - - 0.0000000000007689 79.0
HFD2_k127_21868_27 Cupin 2, conserved barrel domain protein - - - 0.000000000001533 73.0
HFD2_k127_21868_28 Protein of unknown function (DUF1706) - - - 0.0003295 51.0
HFD2_k127_21868_3 N-terminal half of MaoC dehydratase - - - 9.738e-202 633.0
HFD2_k127_21868_4 Amidohydrolase family - - - 4.192e-200 639.0
HFD2_k127_21868_5 acetyl-coa acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 552.0
HFD2_k127_21868_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 547.0
HFD2_k127_21868_7 N-carbamoyl-D-amino acid hydrolase K01459 - 3.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 473.0
HFD2_k127_21868_8 COG1062 Zn-dependent alcohol dehydrogenases, class III K00001,K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006889 475.0
HFD2_k127_21868_9 Pyruvate kinase K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 440.0
HFD2_k127_2223074_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.969e-203 647.0
HFD2_k127_2223074_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000002965 246.0
HFD2_k127_237261_0 Luciferase-like monooxygenase - - - 6.524e-203 638.0
HFD2_k127_237261_1 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 298.0
HFD2_k127_237261_10 methyltransferase - - - 0.00000000000000000000000000001912 129.0
HFD2_k127_237261_11 - - - - 0.000000000000006439 76.0
HFD2_k127_237261_12 Belongs to the thioredoxin family K03671,K03672 - 1.8.1.8 0.000000000000718 69.0
HFD2_k127_237261_13 - - - - 0.0000000001202 65.0
HFD2_k127_237261_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002184 280.0
HFD2_k127_237261_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003592 271.0
HFD2_k127_237261_4 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005794 268.0
HFD2_k127_237261_5 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007351 261.0
HFD2_k127_237261_6 PFAM luciferase-like - - - 0.000000000000000000000000000000000000000000000002364 196.0
HFD2_k127_237261_7 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000005079 174.0
HFD2_k127_237261_8 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000006025 173.0
HFD2_k127_237261_9 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000002577 150.0
HFD2_k127_238871_0 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 389.0
HFD2_k127_238871_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 298.0
HFD2_k127_238871_2 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 289.0
HFD2_k127_238871_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004308 240.0
HFD2_k127_238871_4 membrane K15977 - - 0.000000000000000000000009062 110.0
HFD2_k127_2492628_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 6.2.1.1 0.0 1116.0
HFD2_k127_2492628_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 3.991e-304 942.0
HFD2_k127_2492628_10 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008866 449.0
HFD2_k127_2492628_11 Sigma-54 interaction domain K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 420.0
HFD2_k127_2492628_12 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 413.0
HFD2_k127_2492628_13 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 414.0
HFD2_k127_2492628_14 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 398.0
HFD2_k127_2492628_15 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 389.0
HFD2_k127_2492628_16 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 370.0
HFD2_k127_2492628_17 PFAM AMP-dependent synthetase and ligase K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 361.0
HFD2_k127_2492628_18 PFAM luciferase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 346.0
HFD2_k127_2492628_19 TonB-dependent Receptor Plug Domain K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 327.0
HFD2_k127_2492628_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.975e-273 852.0
HFD2_k127_2492628_20 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001581 296.0
HFD2_k127_2492628_21 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000001511 269.0
HFD2_k127_2492628_22 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000008279 256.0
HFD2_k127_2492628_23 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000001989 247.0
HFD2_k127_2492628_24 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000005227 242.0
HFD2_k127_2492628_25 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001236 253.0
HFD2_k127_2492628_26 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000004328 225.0
HFD2_k127_2492628_27 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000001229 236.0
HFD2_k127_2492628_28 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000000000002756 219.0
HFD2_k127_2492628_29 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000004263 220.0
HFD2_k127_2492628_3 Peptidase family M1 domain K08776 - - 9.038e-228 735.0
HFD2_k127_2492628_30 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000003157 217.0
HFD2_k127_2492628_31 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000004322 211.0
HFD2_k127_2492628_32 Periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000004873 218.0
HFD2_k127_2492628_33 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000623 215.0
HFD2_k127_2492628_34 Pterin binding enzyme K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000004992 217.0
HFD2_k127_2492628_35 PFAM ABC transporter related K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000001219 220.0
HFD2_k127_2492628_36 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000373 177.0
HFD2_k127_2492628_37 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000001771 170.0
HFD2_k127_2492628_38 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000001183 170.0
HFD2_k127_2492628_39 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.000000000000000000000000000000000000000009269 162.0
HFD2_k127_2492628_4 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 2.597e-214 675.0
HFD2_k127_2492628_40 Cobinamide kinase / cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000000001297 161.0
HFD2_k127_2492628_41 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000004507 153.0
HFD2_k127_2492628_42 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K00219,K01069 - 1.3.1.34,3.1.2.6 0.0000000000000000000000000000000000001121 156.0
HFD2_k127_2492628_43 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000185 148.0
HFD2_k127_2492628_44 ECF sigma factor - - - 0.00000000000000000000000000000000009276 148.0
HFD2_k127_2492628_45 Domain of unknown function (DUF4212) - - - 0.000000000000000000000000000000002308 130.0
HFD2_k127_2492628_46 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000002652 139.0
HFD2_k127_2492628_47 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00226,K00254 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.3.5.2,1.3.98.1 0.000000000000000000000000000000003182 141.0
HFD2_k127_2492628_48 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000009803 136.0
HFD2_k127_2492628_49 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000153 146.0
HFD2_k127_2492628_5 Carboxyl transferase domain - - - 6.308e-211 677.0
HFD2_k127_2492628_50 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000005858 131.0
HFD2_k127_2492628_51 S4 RNA-binding domain K04762 - - 0.000000000000000000000000000007288 122.0
HFD2_k127_2492628_52 protein possibly involved in aromatic compounds catabolism - - - 0.00000000000000000000000000001114 127.0
HFD2_k127_2492628_53 4'-phosphopantetheinyl transferase superfamily K00997 - 2.7.8.7 0.00000000000000000000000000006441 123.0
HFD2_k127_2492628_54 SNARE associated Golgi protein - - - 0.00000000000000000000000001124 117.0
HFD2_k127_2492628_55 Conserved hypothetical protein (Lin0512_fam) - - - 0.00000000000000000000000002298 114.0
HFD2_k127_2492628_56 RNA recognition motif - - - 0.0000000000000000000000000704 114.0
HFD2_k127_2492628_57 Vitamin B12 dependent methionine synthase activation - - - 0.00000000000000008123 91.0
HFD2_k127_2492628_58 DoxX K15977 - - 0.0000000000000002642 88.0
HFD2_k127_2492628_59 SMART zinc finger CDGSH-type domain protein - - - 0.0000000000000004317 79.0
HFD2_k127_2492628_6 Methylenetetrahydrofolate reductase K00297,K00547,K00548 - 1.5.1.20,2.1.1.10,2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008781 600.0
HFD2_k127_2492628_60 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000001725 80.0
HFD2_k127_2492628_61 YbbR-like protein - GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - 0.0000000000001747 83.0
HFD2_k127_2492628_63 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000003017 59.0
HFD2_k127_2492628_64 energy transducer activity K03646,K03832 - - 0.0000003642 61.0
HFD2_k127_2492628_65 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07662 - - 0.000007556 53.0
HFD2_k127_2492628_66 Sporulation related domain K03749 - - 0.00007612 53.0
HFD2_k127_2492628_67 - - - - 0.0001414 46.0
HFD2_k127_2492628_7 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 577.0
HFD2_k127_2492628_8 Domain in cystathionine beta-synthase and other proteins. K14446 - 1.3.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 537.0
HFD2_k127_2492628_9 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 490.0
HFD2_k127_254600_0 AMP-binding enzyme C-terminal domain K00666 - - 1.997e-277 859.0
HFD2_k127_254600_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 512.0
HFD2_k127_254600_10 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07644 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 342.0
HFD2_k127_254600_11 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008301 330.0
HFD2_k127_254600_12 PFAM response regulator receiver K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 292.0
HFD2_k127_254600_13 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 289.0
HFD2_k127_254600_14 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 297.0
HFD2_k127_254600_15 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004441 278.0
HFD2_k127_254600_16 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000003499 276.0
HFD2_k127_254600_17 myo-inosose-2 dehydratase activity K00457,K06606 - 1.13.11.27,5.3.99.11 0.000000000000000000000000000000000000000000000000000000000000001324 240.0
HFD2_k127_254600_18 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K04756 - - 0.00000000000000000000000000000000000000000000000000000000000007465 228.0
HFD2_k127_254600_19 P-aminobenzoate N-oxygenase AurF - - - 0.00000000000000000000000000000000000000000000000001747 192.0
HFD2_k127_254600_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 511.0
HFD2_k127_254600_20 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.00000000000000000000000000000000000000000000000003641 196.0
HFD2_k127_254600_21 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000004874 139.0
HFD2_k127_254600_22 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.0000000000000000000000000000008382 128.0
HFD2_k127_254600_23 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.0000000000000000000000184 114.0
HFD2_k127_254600_24 Glcg protein - - - 0.0000000000000000001616 94.0
HFD2_k127_254600_25 Pfam:DUF385 - - - 0.000000000000000004172 93.0
HFD2_k127_254600_26 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000001304 79.0
HFD2_k127_254600_27 Domain of unknown function (DUF4149) - - - 0.000000001819 70.0
HFD2_k127_254600_28 Tetratricopeptide repeat - - - 0.000003525 59.0
HFD2_k127_254600_3 Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities K00842,K14155 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 456.0
HFD2_k127_254600_4 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 461.0
HFD2_k127_254600_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 419.0
HFD2_k127_254600_6 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 404.0
HFD2_k127_254600_7 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 387.0
HFD2_k127_254600_8 PFAM Rhodanese domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 376.0
HFD2_k127_254600_9 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 353.0
HFD2_k127_2558392_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005893 619.0
HFD2_k127_2558392_1 Hydantoinase B/oxoprolinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 601.0
HFD2_k127_2558392_2 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 467.0
HFD2_k127_2558392_3 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 370.0
HFD2_k127_2558392_4 PFAM Peptidase family M20 M25 M40 K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005144 348.0
HFD2_k127_2558392_5 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 319.0
HFD2_k127_2558392_6 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 307.0
HFD2_k127_2558392_7 - K09004 - - 0.0000000000000009697 87.0
HFD2_k127_2558392_8 domain, Protein - - - 0.00006409 51.0
HFD2_k127_2609801_0 NADH-quinone oxidoreductase chain L K00341 - 1.6.5.3 2.258e-197 642.0
HFD2_k127_2609801_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 6.502e-195 620.0
HFD2_k127_2609801_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 447.0
HFD2_k127_2609801_3 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 368.0
HFD2_k127_2609801_4 COGs COG0647 sugar phosphatase of the HAD superfamily K01101,K02566 - 3.1.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 289.0
HFD2_k127_2609801_5 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007831 282.0
HFD2_k127_2609801_6 Fibronectin type 3 domain K12685,K16785,K16786,K16787 - - 0.00000000000000000000000000000000000000000000002511 182.0
HFD2_k127_2609801_7 Glucose inhibited division protein A K21401 - 1.3.99.38 0.00000000000000000000000000000000000000000001127 173.0
HFD2_k127_2669376_0 PQQ-like domain K00117 - 1.1.5.2 2.006e-290 908.0
HFD2_k127_2669376_1 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000005718 245.0
HFD2_k127_2669376_2 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000002177 222.0
HFD2_k127_2669376_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000001119 115.0
HFD2_k127_2669376_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000002074 103.0
HFD2_k127_2694788_0 Zinc-binding dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 494.0
HFD2_k127_2694788_1 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 475.0
HFD2_k127_2694788_10 EamA-like transporter family - - - 0.00000000000000000000001068 114.0
HFD2_k127_2694788_11 Asp/Glu/Hydantoin racemase K16841 - 5.1.99.3 0.00000000000000000000002645 111.0
HFD2_k127_2694788_12 Zinc-binding dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000477 81.0
HFD2_k127_2694788_2 alcohol dehydrogenase (NAD) activity K00001,K00121,K02267,K13980,K18857 GO:0000302,GO:0001101,GO:0001666,GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006970,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009410,GO:0009413,GO:0009414,GO:0009415,GO:0009628,GO:0009636,GO:0009651,GO:0009719,GO:0009725,GO:0009737,GO:0009743,GO:0009744,GO:0010033,GO:0010035,GO:0010038,GO:0010243,GO:0014070,GO:0014074,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0031000,GO:0032355,GO:0033993,GO:0034285,GO:0036270,GO:0036293,GO:0042221,GO:0042493,GO:0042542,GO:0042802,GO:0042803,GO:0043279,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046686,GO:0046983,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0055114,GO:0065007,GO:0070482,GO:0071944,GO:0080134,GO:0080135,GO:0097305,GO:1900037,GO:1900039,GO:1901698,GO:1901700 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 439.0
HFD2_k127_2694788_3 Aminotransferase class-III K00822,K00833 - 2.6.1.18,2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007941 418.0
HFD2_k127_2694788_4 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006949 403.0
HFD2_k127_2694788_5 Encapsulating protein for peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006029 294.0
HFD2_k127_2694788_6 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001468 275.0
HFD2_k127_2694788_7 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000005461 189.0
HFD2_k127_2694788_8 Amidohydrolase family - - - 0.00000000000000000000000000000000000000002996 161.0
HFD2_k127_2694788_9 Evidence 4 Homologs of previously reported genes of K09700 - - 0.0000000000000000000000000000000054 133.0
HFD2_k127_2699720_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009078 541.0
HFD2_k127_2710205_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520,K11177 - 1.17.1.4,1.2.5.3 1.58e-225 739.0
HFD2_k127_2710205_1 ABC transporter transmembrane region K06147,K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 564.0
HFD2_k127_2710205_10 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 349.0
HFD2_k127_2710205_11 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 338.0
HFD2_k127_2710205_12 PFAM ABC transporter K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 323.0
HFD2_k127_2710205_13 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005584 294.0
HFD2_k127_2710205_14 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001179 295.0
HFD2_k127_2710205_15 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003557 297.0
HFD2_k127_2710205_16 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000248 269.0
HFD2_k127_2710205_17 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000005371 255.0
HFD2_k127_2710205_18 Belongs to the UPF0271 (lamB) family K07160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006245 269.0
HFD2_k127_2710205_19 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000004193 269.0
HFD2_k127_2710205_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 460.0
HFD2_k127_2710205_20 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000178 248.0
HFD2_k127_2710205_21 Binding-protein-dependent transport system inner membrane component K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000007353 234.0
HFD2_k127_2710205_22 Domain of unknown function DUF108 - - - 0.00000000000000000000000000000000000000000000000000000000000000002964 231.0
HFD2_k127_2710205_23 Protein of unknown function (DUF2400) - - - 0.000000000000000000000000000000000000000000000000000000000000001971 228.0
HFD2_k127_2710205_24 Binding-protein-dependent transport system inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000006625 235.0
HFD2_k127_2710205_25 Allophanate hydrolase subunit 1 K06351 - - 0.000000000000000000000000000000000000000000000000000000003882 211.0
HFD2_k127_2710205_26 Belongs to the UPF0282 family K07022 - - 0.00000000000000000000000000000000000000000000000000000001094 209.0
HFD2_k127_2710205_27 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000004592 213.0
HFD2_k127_2710205_28 Aminoacyl-tRNA editing domain - - - 0.000000000000000000000000000000000000485 158.0
HFD2_k127_2710205_29 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000000000000000002522 126.0
HFD2_k127_2710205_3 ABC transporter transmembrane region K06147,K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 428.0
HFD2_k127_2710205_31 PFAM Bacterial regulatory proteins, gntR family - - - 0.0000000000000000000000000003871 123.0
HFD2_k127_2710205_32 Redoxin - - - 0.000000000000000000005437 95.0
HFD2_k127_2710205_33 methylated DNA-protein cysteine methyltransferase K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 - 0.0000000000000000000139 99.0
HFD2_k127_2710205_34 Protein conserved in bacteria K09986 - - 0.0000000000000000005581 94.0
HFD2_k127_2710205_35 Protein of unknown function (DUF2889) - - - 0.000000000000001369 90.0
HFD2_k127_2710205_36 Redoxin - - - 0.00000002583 63.0
HFD2_k127_2710205_4 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 402.0
HFD2_k127_2710205_5 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 375.0
HFD2_k127_2710205_6 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 387.0
HFD2_k127_2710205_7 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005248 367.0
HFD2_k127_2710205_8 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 358.0
HFD2_k127_2710205_9 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 346.0
HFD2_k127_2718074_0 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 4.103e-228 722.0
HFD2_k127_2718074_1 Bacterial extracellular solute-binding protein K05813 - - 3.286e-195 619.0
HFD2_k127_2718074_10 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000000002561 70.0
HFD2_k127_2718074_2 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009941 475.0
HFD2_k127_2718074_3 Binding-protein-dependent transport system inner membrane component K05814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 445.0
HFD2_k127_2718074_4 TOBE domain K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 419.0
HFD2_k127_2718074_5 probably responsible for the translocation of the substrate across the membrane K05815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 404.0
HFD2_k127_2718074_6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000004117 230.0
HFD2_k127_2718074_7 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000009262 210.0
HFD2_k127_2718074_8 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000002165 166.0
HFD2_k127_2718074_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000008224 77.0
HFD2_k127_2724123_0 PFAM aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.0 1011.0
HFD2_k127_2724123_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 1.015e-194 621.0
HFD2_k127_2724123_10 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007984 293.0
HFD2_k127_2724123_11 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001452 280.0
HFD2_k127_2724123_12 Short-chain dehydrogenase reductase (SDR) - - - 0.00000000000000000000000000000000000000000000000000000000000000000003427 241.0
HFD2_k127_2724123_13 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000002458 210.0
HFD2_k127_2724123_14 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000005175 205.0
HFD2_k127_2724123_15 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000001229 195.0
HFD2_k127_2724123_16 intermembrane phospholipid transfer K07323 - - 0.0000000000000000000000000000000000000000000000007458 184.0
HFD2_k127_2724123_17 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000007032 175.0
HFD2_k127_2724123_18 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000004794 171.0
HFD2_k127_2724123_19 peroxiredoxin activity K01607 - 4.1.1.44 0.000000000000000000000000000001571 123.0
HFD2_k127_2724123_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 499.0
HFD2_k127_2724123_20 O-methyltransferase - - - 0.00000000000000000000000001402 119.0
HFD2_k127_2724123_21 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000004531 98.0
HFD2_k127_2724123_22 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.00000000000000000005389 94.0
HFD2_k127_2724123_23 PFAM ring hydroxylating dioxygenase, alpha subunit - - - 0.00000000000000008104 87.0
HFD2_k127_2724123_24 Domain of unknown function (DUF4129) - - - 0.000000002652 68.0
HFD2_k127_2724123_25 Acyl dehydratase - - - 0.000000005786 59.0
HFD2_k127_2724123_27 - - - - 0.0002252 51.0
HFD2_k127_2724123_3 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 442.0
HFD2_k127_2724123_4 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 441.0
HFD2_k127_2724123_5 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 383.0
HFD2_k127_2724123_6 PFAM Peptidase M11 gametolysin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 373.0
HFD2_k127_2724123_7 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 337.0
HFD2_k127_2724123_8 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 334.0
HFD2_k127_2724123_9 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006358 337.0
HFD2_k127_2737776_0 Sodium/hydrogen exchanger family K03316 - - 2.911e-257 804.0
HFD2_k127_2737776_1 KR domain - - - 0.000000000000009422 78.0
HFD2_k127_2737776_2 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.0000186 52.0
HFD2_k127_2743035_0 oligopeptide transporter, OPT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 317.0
HFD2_k127_2743035_1 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000002728 141.0
HFD2_k127_2752278_0 Glycosyl transferase, family 2 - - - 6.733e-309 969.0
HFD2_k127_2752278_1 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 3.787e-269 844.0
HFD2_k127_2752278_10 Periplasmic binding protein K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 502.0
HFD2_k127_2752278_11 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 497.0
HFD2_k127_2752278_12 Amino-transferase class IV K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 487.0
HFD2_k127_2752278_13 leucyl aminopeptidase, aminopeptidase T K18028 - 1.13.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 488.0
HFD2_k127_2752278_14 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008415 487.0
HFD2_k127_2752278_15 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 448.0
HFD2_k127_2752278_16 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 443.0
HFD2_k127_2752278_17 Dehydrogenase K00248,K11410,K18244 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 440.0
HFD2_k127_2752278_18 acyl-CoA dehydrogenase K00248,K00249 - 1.3.8.1,1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 438.0
HFD2_k127_2752278_19 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 417.0
HFD2_k127_2752278_2 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 2.586e-255 804.0
HFD2_k127_2752278_20 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 426.0
HFD2_k127_2752278_21 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 418.0
HFD2_k127_2752278_22 Belongs to the DapA family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007243 410.0
HFD2_k127_2752278_23 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 410.0
HFD2_k127_2752278_24 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 415.0
HFD2_k127_2752278_25 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008759 401.0
HFD2_k127_2752278_26 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 397.0
HFD2_k127_2752278_27 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 380.0
HFD2_k127_2752278_28 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 396.0
HFD2_k127_2752278_29 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 387.0
HFD2_k127_2752278_3 PFAM ABC transporter, transmembrane region K06147,K11085 - - 2.352e-237 754.0
HFD2_k127_2752278_30 Branched-chain amino acid transport K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 380.0
HFD2_k127_2752278_31 electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 299.0
HFD2_k127_2752278_32 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 307.0
HFD2_k127_2752278_33 Alcohol dehydrogenase GroES-like domain K00004 - 1.1.1.303,1.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 300.0
HFD2_k127_2752278_34 Oxygenase, catalysing oxidative methylation of damaged DNA K09990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009229 286.0
HFD2_k127_2752278_35 negative regulation of quinolinate biosynthetic process K03392 GO:0001760,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006140,GO:0006520,GO:0006521,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009820,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016043,GO:0016053,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019439,GO:0019752,GO:0022607,GO:0030808,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0033238,GO:0034641,GO:0042402,GO:0042430,GO:0042436,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043648,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046874,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051186,GO:0051193,GO:0051196,GO:0051259,GO:0062012,GO:0062014,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0072330,GO:0072524,GO:0072525,GO:0080090,GO:0090357,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902688,GO:1904984,GO:1904985,GO:1905003,GO:1905004,GO:1905012 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006257 275.0
HFD2_k127_2752278_36 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001306 262.0
HFD2_k127_2752278_37 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002963 258.0
HFD2_k127_2752278_38 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000136 248.0
HFD2_k127_2752278_39 COG0559 Branched-chain amino acid ABC-type transport system, permease components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000241 254.0
HFD2_k127_2752278_4 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.787e-217 688.0
HFD2_k127_2752278_40 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005446 264.0
HFD2_k127_2752278_41 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001566 258.0
HFD2_k127_2752278_42 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000002037 250.0
HFD2_k127_2752278_43 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000002537 231.0
HFD2_k127_2752278_44 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000006064 206.0
HFD2_k127_2752278_45 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000002397 200.0
HFD2_k127_2752278_46 PFAM transferase hexapeptide repeat containing protein - - - 0.00000000000000000000000000000000000000000000003555 176.0
HFD2_k127_2752278_47 PFAM PfkB domain protein - - - 0.00000000000000000000000000000000000000000006147 170.0
HFD2_k127_2752278_48 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000003566 158.0
HFD2_k127_2752278_49 Enoyl-CoA hydratase K16425 GO:0003674,GO:0003824,GO:0004300,GO:0016829,GO:0016835,GO:0016836 - 0.0000000000000000000000000000000000000004642 159.0
HFD2_k127_2752278_5 Belongs to the amidase family K01426 - 3.5.1.4 2.783e-204 667.0
HFD2_k127_2752278_50 Metal binding domain of Ada K00567 - 2.1.1.63 0.0000000000000000000000000000000000000009973 158.0
HFD2_k127_2752278_51 Scavenger mRNA decapping enzyme C-term binding - - - 0.00000000000000000000000000000000000001257 148.0
HFD2_k127_2752278_52 Cyclophilin-like K09143 - - 0.000000000000000000000000000000000002927 143.0
HFD2_k127_2752278_53 UbiC transcription regulator-associated domain protein - - - 0.0000000000000000000000000000000001274 143.0
HFD2_k127_2752278_54 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000009152 110.0
HFD2_k127_2752278_55 Luciferase-like monooxygenase - - - 0.0001185 49.0
HFD2_k127_2752278_6 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 548.0
HFD2_k127_2752278_7 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 548.0
HFD2_k127_2752278_8 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 514.0
HFD2_k127_2752278_9 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005579 501.0
HFD2_k127_2757512_0 Domain of unknown function (DUF1998) K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 4.337e-256 811.0
HFD2_k127_2757512_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 574.0
HFD2_k127_2757512_10 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000002021 226.0
HFD2_k127_2757512_11 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000003066 192.0
HFD2_k127_2757512_12 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000002343 167.0
HFD2_k127_2757512_13 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000005441 167.0
HFD2_k127_2757512_14 C4-type zinc ribbon domain K07164,K22391 - 3.5.4.16 0.0000000000000000000000000003986 123.0
HFD2_k127_2757512_15 - - - - 0.000000001921 68.0
HFD2_k127_2757512_17 Protein of unknown function (DUF721) - - - 0.000000257 59.0
HFD2_k127_2757512_18 PFAM VanZ family protein - - - 0.000003465 57.0
HFD2_k127_2757512_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 446.0
HFD2_k127_2757512_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 421.0
HFD2_k127_2757512_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 381.0
HFD2_k127_2757512_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 382.0
HFD2_k127_2757512_6 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 350.0
HFD2_k127_2757512_7 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 320.0
HFD2_k127_2757512_8 Tetratricopeptide repeat K11935 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 314.0
HFD2_k127_2757512_9 Exonuclease K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005704 267.0
HFD2_k127_2760471_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 489.0
HFD2_k127_2760471_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 434.0
HFD2_k127_2760471_2 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 406.0
HFD2_k127_2760471_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 306.0
HFD2_k127_2760471_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000001876 224.0
HFD2_k127_2760471_5 Histidine kinase K01768,K02482,K02660,K03406,K05874,K07315,K10819,K11525,K11617 - 2.7.13.3,3.1.3.3,4.6.1.1 0.0000000000000000000000000000000000000001072 168.0
HFD2_k127_2760471_6 ferredoxin - GO:0001666,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0036293,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0075136 - 0.000000000000000000000000000000003824 130.0
HFD2_k127_2776618_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 2.285e-226 726.0
HFD2_k127_2776618_1 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 4.06e-220 696.0
HFD2_k127_2776618_2 Luciferase-like monooxygenase - - - 2.109e-212 666.0
HFD2_k127_2776618_3 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 516.0
HFD2_k127_2776618_4 Belongs to the MurCDEF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000151 292.0
HFD2_k127_2776618_5 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000004671 229.0
HFD2_k127_2776618_6 Nitronate monooxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000006688 219.0
HFD2_k127_2776618_7 AhpC/TSA family - - - 0.0000000000000000000000000000000000000000000000000000000001088 210.0
HFD2_k127_2776618_8 - - - - 0.00000000000000000000000000000000000000000000000000000009883 203.0
HFD2_k127_2776618_9 Oxidoreductase - - - 0.00000000000000000000000000000000000000000000004409 183.0
HFD2_k127_2810688_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 570.0
HFD2_k127_2810688_1 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000001074 157.0
HFD2_k127_2813764_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K04090 - 1.2.7.8 0.0 1299.0
HFD2_k127_2813764_1 FtsX-like permease family K02004 - - 3.984e-205 676.0
HFD2_k127_2813764_10 permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009723 268.0
HFD2_k127_2813764_11 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000004341 221.0
HFD2_k127_2813764_12 S4 RNA-binding domain K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000000000001607 220.0
HFD2_k127_2813764_13 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000001239 208.0
HFD2_k127_2813764_14 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.00000000000000000000000000000000000000008168 172.0
HFD2_k127_2813764_15 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01153 - 3.1.21.3 0.0000000000000000000000000000005968 123.0
HFD2_k127_2813764_16 PFAM ROSMUCR transcriptional regulator - - - 0.0000000001167 68.0
HFD2_k127_2813764_17 PFAM Uncharacterised protein family UPF0150 - - - 0.0000103 53.0
HFD2_k127_2813764_2 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 531.0
HFD2_k127_2813764_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 464.0
HFD2_k127_2813764_4 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 427.0
HFD2_k127_2813764_5 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 370.0
HFD2_k127_2813764_6 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 332.0
HFD2_k127_2813764_7 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 303.0
HFD2_k127_2813764_8 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 299.0
HFD2_k127_2813764_9 lipoprotein transporter activity K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004017 273.0
HFD2_k127_2838754_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 3.149e-205 664.0
HFD2_k127_2838754_1 ABC-type dipeptide transport system periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 599.0
HFD2_k127_2838754_10 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008787 316.0
HFD2_k127_2838754_11 aminopeptidase activity K18028 - 1.13.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005408 293.0
HFD2_k127_2838754_12 Carbon-nitrogen hydrolase K01431 - 3.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000005531 267.0
HFD2_k127_2838754_13 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001137 254.0
HFD2_k127_2838754_14 Bacterial extracellular solute-binding protein K02020 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704 - 0.0000000000000000000000000000000000000000000000000000000000005783 220.0
HFD2_k127_2838754_15 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000003048 227.0
HFD2_k127_2838754_16 Predicted membrane protein (DUF2142) - - - 0.0000000000000000000000000000000000000000000000000000000003893 220.0
HFD2_k127_2838754_17 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000129 203.0
HFD2_k127_2838754_18 Transcriptional regulator K21900 - - 0.00000000000000000000000000000000000000000000000000001917 201.0
HFD2_k127_2838754_19 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000001299 200.0
HFD2_k127_2838754_2 Glutamine synthetase N-terminal domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 580.0
HFD2_k127_2838754_20 TRAP transporter, solute receptor (TAXI family K07080 - - 0.0000000000000000000000000000000000000000000008837 179.0
HFD2_k127_2838754_21 - - - - 0.00000000000000000000000000000000000000000001539 172.0
HFD2_k127_2838754_22 - - - - 0.00000000000000000000000000000000000000001363 163.0
HFD2_k127_2838754_23 Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000007664 167.0
HFD2_k127_2838754_24 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000006854 149.0
HFD2_k127_2838754_25 STAS domain K06378 - - 0.0000000000000000000000378 113.0
HFD2_k127_2838754_26 Histidine kinase-like ATPase domain - - - 0.0000000000000005081 83.0
HFD2_k127_2838754_27 response regulator, receiver - - - 0.000000000002665 80.0
HFD2_k127_2838754_28 Short C-terminal domain - - - 0.00000000008673 70.0
HFD2_k127_2838754_3 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 454.0
HFD2_k127_2838754_4 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 418.0
HFD2_k127_2838754_5 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 415.0
HFD2_k127_2838754_6 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 403.0
HFD2_k127_2838754_7 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 370.0
HFD2_k127_2838754_8 rieske 2fe-2s - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 350.0
HFD2_k127_2838754_9 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 346.0
HFD2_k127_285503_0 Bacterial DNA polymerase III alpha subunit - - - 5.802e-305 970.0
HFD2_k127_285503_1 dehydrogenase - - - 6.792e-209 669.0
HFD2_k127_285503_10 transferase activity, transferring glycosyl groups K20444 - - 0.000000000000000000000000000000000000000000000000000000184 221.0
HFD2_k127_285503_11 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000002111 199.0
HFD2_k127_285503_12 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000007459 202.0
HFD2_k127_285503_13 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.000000000000000000000000000000000000000000006537 181.0
HFD2_k127_285503_14 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000001766 171.0
HFD2_k127_285503_15 Putative regulatory protein - - - 0.000000000000000000000000000000007798 136.0
HFD2_k127_285503_16 recA bacterial DNA recombination protein - - - 0.000000000000000000000005245 109.0
HFD2_k127_285503_2 COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 593.0
HFD2_k127_285503_3 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 539.0
HFD2_k127_285503_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 300.0
HFD2_k127_285503_5 membrane - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 294.0
HFD2_k127_285503_6 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001509 284.0
HFD2_k127_285503_7 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005385 257.0
HFD2_k127_285503_8 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009597 254.0
HFD2_k127_285503_9 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.000000000000000000000000000000000000000000000000000000001308 224.0
HFD2_k127_2857317_0 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000003494 193.0
HFD2_k127_2857317_1 peroxiredoxin activity - - - 0.000000000000000000000007303 105.0
HFD2_k127_2857317_2 - - - - 0.00000006976 58.0
HFD2_k127_2869610_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005247 387.0
HFD2_k127_2869610_1 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000005676 183.0
HFD2_k127_2931586_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 5.984e-285 895.0
HFD2_k127_2931586_1 AMP-dependent synthetase - - - 7.306e-254 812.0
HFD2_k127_2931586_10 two-component system sensor protein - - - 0.000000000000000000000000000000000000000000000000000000000000007806 232.0
HFD2_k127_2931586_11 bacterial OsmY and nodulation domain - - - 0.0000000000000000000000000000000000000000000000000231 200.0
HFD2_k127_2931586_12 Universal stress protein family - - - 0.00000000000000000000000000000000000000000002083 165.0
HFD2_k127_2931586_13 DNA polymerase K02347 - - 0.0000000000000000000000000000000000002531 153.0
HFD2_k127_2931586_14 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000003435 145.0
HFD2_k127_2931586_15 CBS domain K04767 - - 0.00000000000000000000000000000003533 139.0
HFD2_k127_2931586_16 GYD domain - - - 0.0000000000000000000000000000002124 127.0
HFD2_k127_2931586_17 Cbs domain K04767 - - 0.00000000000000000000001551 109.0
HFD2_k127_2931586_19 IMP dehydrogenase activity K04767 - - 0.000000000000000000001063 107.0
HFD2_k127_2931586_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 3.031e-249 779.0
HFD2_k127_2931586_20 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000004333 99.0
HFD2_k127_2931586_21 Universal stress protein K06149 - - 0.00000000000000002313 89.0
HFD2_k127_2931586_22 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.00000000000000842 79.0
HFD2_k127_2931586_23 Acetamidase/Formamidase family - - - 0.000000000003674 69.0
HFD2_k127_2931586_3 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 1.501e-205 651.0
HFD2_k127_2931586_4 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 3.065e-200 657.0
HFD2_k127_2931586_5 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 608.0
HFD2_k127_2931586_6 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 434.0
HFD2_k127_2931586_7 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 419.0
HFD2_k127_2931586_8 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 386.0
HFD2_k127_2931586_9 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008528 306.0
HFD2_k127_2940789_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 484.0
HFD2_k127_2940789_1 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 396.0
HFD2_k127_2975176_0 Formiminotransferase domain, N-terminal subdomain K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 353.0
HFD2_k127_2975176_1 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000001799 205.0
HFD2_k127_3007882_0 DNA polymerase type-B family K02336 - 2.7.7.7 9.339e-217 706.0
HFD2_k127_3007882_1 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 362.0
HFD2_k127_3007882_2 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000004144 237.0
HFD2_k127_3007882_3 photosynthesis - - - 0.000000000000000000000000000000000000000000000000009174 186.0
HFD2_k127_3007882_4 RNA recognition motif - - - 0.0000000000000000000000002222 109.0
HFD2_k127_3007882_5 RDD family - - - 0.00000000000003708 82.0
HFD2_k127_3007882_6 Domain of unknown function (DUF309) K09763 - - 0.000000003798 70.0
HFD2_k127_3007882_7 4-Hydroxyphenylpyruvate dioxygenase K00406,K05606,K17315 - 5.1.99.1 0.00003024 47.0
HFD2_k127_3007882_8 Rhodanese-like domain - - - 0.0001868 53.0
HFD2_k127_3033974_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 621.0
HFD2_k127_3033974_1 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 363.0
HFD2_k127_3033974_2 AsmA family - - - 0.0000000000000000000000000000000000000000005195 182.0
HFD2_k127_3033974_3 SMART Transport-associated and nodulation region K04065 - - 0.0000323 51.0
HFD2_k127_3034093_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1054.0
HFD2_k127_3034093_1 Thiol disulfide interchange protein K04084,K08344 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 619.0
HFD2_k127_3034093_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 412.0
HFD2_k127_3034093_3 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006431 386.0
HFD2_k127_3034093_4 Protein of unknown function (DUF3500) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003038 304.0
HFD2_k127_3034093_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002719 246.0
HFD2_k127_3034093_6 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.000000000000000000000000000000000000000000000000002344 188.0
HFD2_k127_3059353_0 PFAM ABC transporter K01990,K13926 - - 0.0 1380.0
HFD2_k127_3059353_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1287.0
HFD2_k127_3059353_10 secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 325.0
HFD2_k127_3059353_11 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 304.0
HFD2_k127_3059353_12 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009886 270.0
HFD2_k127_3059353_13 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004965 250.0
HFD2_k127_3059353_14 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000004891 249.0
HFD2_k127_3059353_15 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000002226 242.0
HFD2_k127_3059353_16 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000006932 243.0
HFD2_k127_3059353_17 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000004305 218.0
HFD2_k127_3059353_18 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000007712 179.0
HFD2_k127_3059353_19 - - - - 0.0000000000000000000000003523 111.0
HFD2_k127_3059353_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 2.552e-286 898.0
HFD2_k127_3059353_20 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000001572 108.0
HFD2_k127_3059353_21 - - - - 0.00000000000000000002763 95.0
HFD2_k127_3059353_22 Alcohol dehydrogenase GroES-like domain - - - 0.00007058 50.0
HFD2_k127_3059353_23 CBS domain - GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0030312,GO:0035821,GO:0036293,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0070482,GO:0071944,GO:0075136 - 0.0001645 51.0
HFD2_k127_3059353_3 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 616.0
HFD2_k127_3059353_4 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 569.0
HFD2_k127_3059353_5 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 531.0
HFD2_k127_3059353_6 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 527.0
HFD2_k127_3059353_7 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 521.0
HFD2_k127_3059353_8 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 450.0
HFD2_k127_3059353_9 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 427.0
HFD2_k127_3066141_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 478.0
HFD2_k127_3066141_1 MFS_1 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 449.0
HFD2_k127_3066141_10 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000009581 169.0
HFD2_k127_3066141_11 PFAM Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000136 174.0
HFD2_k127_3066141_12 Glyoxalase-like domain K01759,K01849,K05606 - 4.4.1.5,5.1.99.1,5.4.99.2 0.00000000000000000000000000004715 126.0
HFD2_k127_3066141_13 spore germination K03298 - - 0.00000000000000000000000000006117 134.0
HFD2_k127_3066141_14 GYD domain - - - 0.000000000000000000000000001472 121.0
HFD2_k127_3066141_15 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000741 122.0
HFD2_k127_3066141_16 - - - - 0.000000983 56.0
HFD2_k127_3066141_17 - - - - 0.00003173 55.0
HFD2_k127_3066141_18 Cyclic nucleotide-monophosphate binding domain - - - 0.0000413 53.0
HFD2_k127_3066141_19 ThiS family K03636 - - 0.0002151 49.0
HFD2_k127_3066141_2 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 366.0
HFD2_k127_3066141_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 GO:0000255,GO:0000256,GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009436,GO:0009442,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042737,GO:0043436,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046483,GO:0046487,GO:0046700,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 326.0
HFD2_k127_3066141_4 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 322.0
HFD2_k127_3066141_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 307.0
HFD2_k127_3066141_6 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000253 288.0
HFD2_k127_3066141_7 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000002828 255.0
HFD2_k127_3066141_8 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000000000000000003225 252.0
HFD2_k127_3066141_9 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000009068 184.0
HFD2_k127_306663_0 Cytochrome C and Quinol oxidase polypeptide I K15862 - 1.9.3.1 0.0 1072.0
HFD2_k127_306663_1 Putative metal-binding domain of cation transport ATPase K01533 - 3.6.3.4 4.887e-236 756.0
HFD2_k127_306663_10 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000001644 166.0
HFD2_k127_306663_11 sarcosine oxidase K00301 - 1.5.3.1 0.0000000000000000000000000000000000000001576 169.0
HFD2_k127_306663_12 ATP-grasp domain - - - 0.000000000000000000000000000000005495 137.0
HFD2_k127_306663_13 FixH - - - 0.000000000000000000000000000002971 127.0
HFD2_k127_306663_14 PFAM UspA domain protein - - - 0.00000000000000000000002812 108.0
HFD2_k127_306663_15 Universal stress protein - - - 0.000000000000000000002743 101.0
HFD2_k127_306663_16 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000003294 98.0
HFD2_k127_306663_17 Universal stress protein - - - 0.000000000000000001485 91.0
HFD2_k127_306663_18 Universal stress protein - - - 0.00000000000000001577 88.0
HFD2_k127_306663_19 YCII-related domain K09780 - - 0.00000000000008487 83.0
HFD2_k127_306663_2 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 509.0
HFD2_k127_306663_20 COG3806 Anti-sigma factor - - - 0.0000000000004611 78.0
HFD2_k127_306663_21 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.0000000003688 72.0
HFD2_k127_306663_22 ChrR Cupin-like domain - - - 0.0000000008633 68.0
HFD2_k127_306663_23 Cytochrome c - - - 0.00000002558 61.0
HFD2_k127_306663_25 Protein of unknown function (DUF2892) - - - 0.0000005353 62.0
HFD2_k127_306663_26 Cytochrome oxidase maturation protein - - - 0.0000008593 61.0
HFD2_k127_306663_27 AMP binding - - - 0.000001413 60.0
HFD2_k127_306663_28 Universal stress protein family - - - 0.00002681 51.0
HFD2_k127_306663_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 500.0
HFD2_k127_306663_4 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007342 504.0
HFD2_k127_306663_5 Short-chain dehydrogenase reductase (SDR) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008805 278.0
HFD2_k127_306663_6 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.0000000000000000000000000000000000000000000000000002007 192.0
HFD2_k127_306663_7 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000499 194.0
HFD2_k127_306663_8 Universal stress protein family - - - 0.00000000000000000000000000000000000000000001053 166.0
HFD2_k127_306663_9 Adenylylsulphate kinase K00860 - 2.7.1.25 0.00000000000000000000000000000000000000000001569 177.0
HFD2_k127_3095385_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 373.0
HFD2_k127_3095947_0 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 471.0
HFD2_k127_3095947_1 PFAM Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 408.0
HFD2_k127_3095947_10 DinB family - - - 0.0000000000002655 77.0
HFD2_k127_3095947_11 Ferritin-like domain - - - 0.000000001199 70.0
HFD2_k127_3095947_2 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000574 261.0
HFD2_k127_3095947_3 PFAM amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000001702 185.0
HFD2_k127_3095947_4 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000002445 201.0
HFD2_k127_3095947_5 3'-5' exonuclease activity K03547 - - 0.000000000000000000000000000000000000000000001348 175.0
HFD2_k127_3095947_6 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000003871 171.0
HFD2_k127_3095947_7 intermembrane phospholipid transfer K07323 - - 0.000000000000000000000004196 117.0
HFD2_k127_3095947_8 Hsp20/alpha crystallin family - - - 0.000000000000000000000004738 108.0
HFD2_k127_3095947_9 amine dehydrogenase activity K00355 - 1.6.5.2 0.00000000000000008806 93.0
HFD2_k127_310797_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1333.0
HFD2_k127_310797_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1047.0
HFD2_k127_310797_10 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 511.0
HFD2_k127_310797_11 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 505.0
HFD2_k127_310797_12 secondary active sulfate transmembrane transporter activity K06901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 501.0
HFD2_k127_310797_13 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 422.0
HFD2_k127_310797_14 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005197 415.0
HFD2_k127_310797_15 RNA polymerase sigma-54 factor K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 405.0
HFD2_k127_310797_16 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 387.0
HFD2_k127_310797_17 Belongs to the SIS family. GutQ KpsF subfamily K01627,K03281,K06041 - 2.5.1.55,5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 370.0
HFD2_k127_310797_18 Belongs to the KdsA family K01627 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0022607,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 364.0
HFD2_k127_310797_19 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 334.0
HFD2_k127_310797_2 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0 1028.0
HFD2_k127_310797_20 Belongs to the proline racemase family K01777 GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855,GO:0036361,GO:0047580,GO:0047661 5.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 330.0
HFD2_k127_310797_21 P-loop ATPase protein family K06958 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 326.0
HFD2_k127_310797_22 Phage integrase, N-terminal SAM-like domain K03733,K04763 GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 291.0
HFD2_k127_310797_23 Permease YjgP YjgQ family protein K07091,K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000075 308.0
HFD2_k127_310797_24 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005247 283.0
HFD2_k127_310797_25 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001631 287.0
HFD2_k127_310797_26 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001036 269.0
HFD2_k127_310797_27 Phenylacetic acid catabolic protein K02609 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000000000123 254.0
HFD2_k127_310797_28 ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001884 248.0
HFD2_k127_310797_29 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000001329 218.0
HFD2_k127_310797_3 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1023.0
HFD2_k127_310797_30 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000003735 192.0
HFD2_k127_310797_31 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000639 204.0
HFD2_k127_310797_32 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000001053 184.0
HFD2_k127_310797_33 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000006203 185.0
HFD2_k127_310797_34 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000006465 154.0
HFD2_k127_310797_35 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.0000000000000000000000000000000005081 151.0
HFD2_k127_310797_36 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000001448 136.0
HFD2_k127_310797_37 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000232 122.0
HFD2_k127_310797_38 Polymer-forming cytoskeletal - - - 0.0000000000000000000002305 105.0
HFD2_k127_310797_39 Evidence 5 No homology to any previously reported sequences K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.0000000000000000000004443 104.0
HFD2_k127_310797_4 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702,K08999 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 2.054e-269 852.0
HFD2_k127_310797_40 TIGRFAM lipopolysaccharide transport periplasmic protein LptA K09774 - - 0.0000000000000000001895 100.0
HFD2_k127_310797_42 Lipopolysaccharide-assembly, LptC-related - - - 0.000000000001075 76.0
HFD2_k127_310797_43 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000001521 71.0
HFD2_k127_310797_5 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 4.093e-268 845.0
HFD2_k127_310797_6 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 9.025e-222 700.0
HFD2_k127_310797_7 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.539e-199 653.0
HFD2_k127_310797_8 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 571.0
HFD2_k127_310797_9 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000577 586.0
HFD2_k127_321347_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 3.68e-201 636.0
HFD2_k127_321347_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 6.019e-197 636.0
HFD2_k127_321347_10 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000005255 248.0
HFD2_k127_321347_11 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000003893 226.0
HFD2_k127_321347_12 Peptidase family M23 K21471 GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.00000000000000000000000000000000000000000000000000003928 209.0
HFD2_k127_321347_13 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000002841 190.0
HFD2_k127_321347_14 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000001593 190.0
HFD2_k127_321347_15 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000003361 162.0
HFD2_k127_321347_16 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000395 149.0
HFD2_k127_321347_17 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000001075 134.0
HFD2_k127_321347_18 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.0000000000000000002071 94.0
HFD2_k127_321347_19 - - - - 0.0000000000002006 85.0
HFD2_k127_321347_2 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 6.597e-197 644.0
HFD2_k127_321347_20 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.000004433 51.0
HFD2_k127_321347_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K01876,K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 596.0
HFD2_k127_321347_4 Two component, sigma54 specific, transcriptional regulator, Fis family K07712,K07714 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 477.0
HFD2_k127_321347_5 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 443.0
HFD2_k127_321347_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 378.0
HFD2_k127_321347_7 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 316.0
HFD2_k127_321347_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007771 281.0
HFD2_k127_321347_9 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000124 272.0
HFD2_k127_321589_0 Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 531.0
HFD2_k127_321589_1 AMP-binding enzyme C-terminal domain K04116,K12507 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 516.0
HFD2_k127_321589_10 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000009315 243.0
HFD2_k127_321589_11 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000002664 225.0
HFD2_k127_321589_12 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000007547 199.0
HFD2_k127_321589_13 PFAM Lytic transglycosylase catalytic K08309 - - 0.0000000000000000000000000000000000000000003755 178.0
HFD2_k127_321589_14 COG0694 Thioredoxin-like proteins and domains - - - 0.0000000000000000000000000001376 118.0
HFD2_k127_321589_15 Vitamin K epoxide reductase family - - - 0.0000000000000000000000000003225 123.0
HFD2_k127_321589_16 cell redox homeostasis - - - 0.000000000000000000257 89.0
HFD2_k127_321589_17 RDD family - - - 0.0000000000009678 74.0
HFD2_k127_321589_18 - - - - 0.000812 51.0
HFD2_k127_321589_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 500.0
HFD2_k127_321589_3 Oxidoreductase molybdopterin binding domain K07147 GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0016672,GO:0016675,GO:0019538,GO:0030091,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0043546,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0055114,GO:0071704,GO:0097159,GO:1901363,GO:1901530,GO:1901564,GO:1901700 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 455.0
HFD2_k127_321589_4 Acyl-CoA dehydrogenase, N-terminal domain K04117 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 439.0
HFD2_k127_321589_5 Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily K01661 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 370.0
HFD2_k127_321589_6 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 370.0
HFD2_k127_321589_7 KR domain K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 361.0
HFD2_k127_321589_8 PFAM Alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 302.0
HFD2_k127_321589_9 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007878 267.0
HFD2_k127_3294309_0 sigma factor activity K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007568 472.0
HFD2_k127_3294309_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 451.0
HFD2_k127_3294309_2 COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 336.0
HFD2_k127_3294309_3 Ketopantoate reductase PanE/ApbA C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007541 261.0
HFD2_k127_3294309_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000679 177.0
HFD2_k127_3294309_5 - - - - 0.00000000000000004364 87.0
HFD2_k127_3294309_6 Protein of unknown function (DUF2384) K15359 - 1.14.13.163 0.000004993 57.0
HFD2_k127_3294309_7 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0004168 52.0
HFD2_k127_3522800_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 498.0
HFD2_k127_3522800_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000004303 117.0
HFD2_k127_3522800_2 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000002192 91.0
HFD2_k127_3522800_3 S-layer homology domain - - - 0.00000000001374 76.0
HFD2_k127_3522800_4 - - - - 0.00000000004904 66.0
HFD2_k127_3522800_5 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.00000003798 65.0
HFD2_k127_3522800_6 iron dependent repressor - - - 0.000642 49.0
HFD2_k127_3538820_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 306.0
HFD2_k127_3538820_1 response regulator receiver K13041 - - 0.0000000000000000000000000000000000000000000000000002037 197.0
HFD2_k127_3538820_2 cheY-homologous receiver domain - - - 0.00000000000000000000000009205 111.0
HFD2_k127_3538820_3 - - - - 0.0000000000000000003328 98.0
HFD2_k127_3567075_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007767 354.0
HFD2_k127_3567075_1 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 329.0
HFD2_k127_3567075_10 Nitroreductase family K04719 - 1.13.11.79 0.00000000000000001409 94.0
HFD2_k127_3567075_11 Acetyltransferase (GNAT) domain - - - 0.000000000000000228 85.0
HFD2_k127_3567075_12 Glycine zipper - - - 0.0000000000000926 79.0
HFD2_k127_3567075_13 Nacht domain - - - 0.000000000006395 70.0
HFD2_k127_3567075_14 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000001837 65.0
HFD2_k127_3567075_15 Beta-lactamase superfamily domain - - - 0.000000004214 63.0
HFD2_k127_3567075_16 COG3666 Transposase and inactivated derivatives - - - 0.000002998 49.0
HFD2_k127_3567075_17 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009245,GO:0009247,GO:0009259,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0019637,GO:0019693,GO:0019752,GO:0019842,GO:0030312,GO:0031177,GO:0032787,GO:0033218,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046483,GO:0046493,GO:0048037,GO:0051186,GO:0051192,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0072521,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901576,GO:1903509 - 0.00002618 56.0
HFD2_k127_3567075_18 PFAM GCN5-related N-acetyltransferase - - - 0.00003168 53.0
HFD2_k127_3567075_19 MacB-like periplasmic core domain K02004 - - 0.0003635 53.0
HFD2_k127_3567075_2 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008178 264.0
HFD2_k127_3567075_3 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000002846 231.0
HFD2_k127_3567075_4 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000006378 183.0
HFD2_k127_3567075_5 ABC transporter K02003 - - 0.000000000000000000000000000000000000004184 163.0
HFD2_k127_3567075_7 - - - - 0.000000000000000000000000000007761 123.0
HFD2_k127_3567075_8 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019171,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576 4.2.1.59 0.000000000000000000000001119 109.0
HFD2_k127_3567075_9 - - - - 0.000000000000000000000003817 109.0
HFD2_k127_3593578_0 aminotransferase class I and II K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 480.0
HFD2_k127_3593578_1 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000002679 220.0
HFD2_k127_3593578_2 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000004605 198.0
HFD2_k127_3593578_3 GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000008814 170.0
HFD2_k127_3593578_4 HD domain K07023 - - 0.00000000000000000000003284 101.0
HFD2_k127_3593578_5 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0005579 50.0
HFD2_k127_3596803_0 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 395.0
HFD2_k127_3596803_1 NAD(P) transhydrogenase beta subunit K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 336.0
HFD2_k127_3605610_0 Belongs to the transketolase family K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 398.0
HFD2_k127_3605610_1 Belongs to the ompA family K03640 GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032153,GO:0044425,GO:0044462,GO:0044464,GO:0051301,GO:0071944,GO:0098552 - 0.00000000000000000000001913 111.0
HFD2_k127_3605853_0 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 400.0
HFD2_k127_3605853_1 Transposase K07481 - - 0.000000000000000496 78.0
HFD2_k127_3605853_2 Belongs to the 'phage' integrase family - - - 0.000000000001718 76.0
HFD2_k127_3605853_3 Evidence 4 Homologs of previously reported genes of - - - 0.00000000002096 68.0
HFD2_k127_3613207_0 Bacterial extracellular solute-binding protein K02027,K10236 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 326.0
HFD2_k127_3613207_1 Protein of unknown function (DUF1207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 320.0
HFD2_k127_3613207_2 Binding-protein-dependent transport system inner membrane component K02025,K10237,K15771 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.0000000000000000000000000000000000000000000000000000000000000000000000042 267.0
HFD2_k127_3613207_3 Binding-protein-dependent transport system inner membrane component K02026,K10238 - - 0.00000000000000000000000000000000000000000000000000000000000000001927 245.0
HFD2_k127_3613207_4 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000006149 206.0
HFD2_k127_3634563_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 338.0
HFD2_k127_3634563_1 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000004233 134.0
HFD2_k127_3641647_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 1.233e-299 936.0
HFD2_k127_3669639_0 Hydantoinase/oxoprolinase - - - 1.566e-277 877.0
HFD2_k127_3669639_1 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 8.617e-262 818.0
HFD2_k127_3669639_10 MaoC like domain - - - 0.00000000000000000000000000000000000000005728 156.0
HFD2_k127_3669639_11 xylanase chitin deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000009042 170.0
HFD2_k127_3669639_12 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000001071 151.0
HFD2_k127_3669639_13 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000003434 146.0
HFD2_k127_3669639_14 php family - - - 0.0000000000000000004774 94.0
HFD2_k127_3669639_15 MaoC like domain K17865 - 4.2.1.55 0.000000000002674 72.0
HFD2_k127_3669639_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 503.0
HFD2_k127_3669639_3 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 380.0
HFD2_k127_3669639_4 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 374.0
HFD2_k127_3669639_5 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 367.0
HFD2_k127_3669639_6 Hydantoinase B/oxoprolinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 344.0
HFD2_k127_3669639_7 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005699 280.0
HFD2_k127_3669639_8 Monogalactosyldiacylglycerol (MGDG) synthase K03429 - 2.4.1.315 0.00000000000000000000000000000000000000000000000000000000000006479 233.0
HFD2_k127_3669639_9 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000004036 185.0
HFD2_k127_3699498_0 capsule polysaccharide biosynthetic process K13687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 340.0
HFD2_k127_3699498_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 319.0
HFD2_k127_3699498_10 HEAT repeat - - - 0.00000015 64.0
HFD2_k127_3699498_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002406 246.0
HFD2_k127_3699498_3 SMART Tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000001564 211.0
HFD2_k127_3699498_5 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000002459 185.0
HFD2_k127_3699498_6 - - - - 0.0000000000000000000000000000000000000005166 170.0
HFD2_k127_3699498_7 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000123 109.0
HFD2_k127_3699498_8 Phosphopantetheine attachment site - - - 0.000000000497 73.0
HFD2_k127_3699498_9 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000001402 65.0
HFD2_k127_370274_0 lipopolysaccharide transport K22110 - - 0.0 1295.0
HFD2_k127_370274_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.228e-198 633.0
HFD2_k127_370274_2 cellular water homeostasis K03442,K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001604 286.0
HFD2_k127_370274_3 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000722 253.0
HFD2_k127_370274_4 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K00851,K00852,K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,2.7.1.15,5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000004747 250.0
HFD2_k127_370274_5 - - - - 0.0000000000000000000000000000000000000000000001762 178.0
HFD2_k127_370274_6 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000006201 177.0
HFD2_k127_370274_7 Putative zinc-finger - - - 0.000000001102 68.0
HFD2_k127_379774_0 choline dehydrogenase activity - - - 3.238e-268 837.0
HFD2_k127_379774_1 lipopolysaccharide transport K22110 - - 6.731e-206 647.0
HFD2_k127_379774_2 type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 521.0
HFD2_k127_379774_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007191 409.0
HFD2_k127_379774_4 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009818 376.0
HFD2_k127_379774_5 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004017 272.0
HFD2_k127_379774_6 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000207 224.0
HFD2_k127_379774_7 Methylmuconolactone methyl-isomerase - - - 0.00000000000000000000000000000000000000000000000000001072 198.0
HFD2_k127_380032_0 Major facilitator Superfamily K00943,K08217,K18833 - 2.7.4.9 0.0000000000000000000000000000000000000000000000006544 178.0
HFD2_k127_380032_1 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000009178 84.0
HFD2_k127_380032_2 PFAM Squalene phytoene synthase K00801 - 2.5.1.21 0.0000000002242 73.0
HFD2_k127_3832633_0 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 582.0
HFD2_k127_3832633_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 537.0
HFD2_k127_3832633_10 ferredoxin K05524 - - 0.000000000000000000000000000000000005563 139.0
HFD2_k127_3832633_11 Amidohydrolase K07045 - - 0.00000000000000000000000002737 119.0
HFD2_k127_3832633_12 Virulence factor BrkB K07058 - - 0.00000000000000000000005643 100.0
HFD2_k127_3832633_13 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.00000017 63.0
HFD2_k127_3832633_14 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.0000007387 62.0
HFD2_k127_3832633_15 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.000001714 59.0
HFD2_k127_3832633_2 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 451.0
HFD2_k127_3832633_3 COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase K02031,K02032,K13892 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 459.0
HFD2_k127_3832633_4 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 426.0
HFD2_k127_3832633_5 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009168 421.0
HFD2_k127_3832633_6 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 382.0
HFD2_k127_3832633_7 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003742 296.0
HFD2_k127_3832633_8 NADH pyrophosphatase zinc ribbon domain K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000003562 285.0
HFD2_k127_3832633_9 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000001416 248.0
HFD2_k127_3883903_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 5.141e-231 732.0
HFD2_k127_3883903_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.845e-214 694.0
HFD2_k127_3883903_10 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005766 291.0
HFD2_k127_3883903_11 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000002518 265.0
HFD2_k127_3883903_12 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000005292 192.0
HFD2_k127_3883903_13 domain protein - - - 0.000000000000000000000000000000000000000000000000007683 196.0
HFD2_k127_3883903_14 chlorophyll binding K03640 - - 0.000000000000000000000000000000000001231 143.0
HFD2_k127_3883903_15 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000001737 143.0
HFD2_k127_3883903_16 Protein of unknown function (DUF2914) - - - 0.0000000000000000000000000000001062 142.0
HFD2_k127_3883903_17 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.000000000000000000000000000003499 131.0
HFD2_k127_3883903_18 - - - - 0.00000000000000001793 89.0
HFD2_k127_3883903_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 4.236e-196 644.0
HFD2_k127_3883903_20 - - - - 0.0000000003693 70.0
HFD2_k127_3883903_3 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 546.0
HFD2_k127_3883903_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 395.0
HFD2_k127_3883903_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009545 362.0
HFD2_k127_3883903_6 AAA domain K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 308.0
HFD2_k127_3883903_7 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 293.0
HFD2_k127_3883903_8 Radical SAM domain protein K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002089 279.0
HFD2_k127_3883903_9 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003024 284.0
HFD2_k127_3907847_0 PFAM Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 458.0
HFD2_k127_3907847_1 Rieske [2Fe-2S] domain K19982 - - 0.000000000000000000000000001477 119.0
HFD2_k127_4002770_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 4.224e-266 856.0
HFD2_k127_4002770_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 1.859e-205 664.0
HFD2_k127_4002770_10 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006686 258.0
HFD2_k127_4002770_11 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000002574 234.0
HFD2_k127_4002770_12 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000001942 240.0
HFD2_k127_4002770_13 imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000002123 245.0
HFD2_k127_4002770_14 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000001788 224.0
HFD2_k127_4002770_15 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000001632 229.0
HFD2_k127_4002770_16 Histidine biosynthesis bifunctional protein hisIE K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000002412 210.0
HFD2_k127_4002770_17 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000001119 192.0
HFD2_k127_4002770_18 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000000000000000002996 198.0
HFD2_k127_4002770_19 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.0000000000000000000000000000000000000000000000006002 195.0
HFD2_k127_4002770_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 529.0
HFD2_k127_4002770_20 MlaD protein K02067 - - 0.000000000000000000000000000000000000000005987 170.0
HFD2_k127_4002770_21 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000007817 162.0
HFD2_k127_4002770_22 Binds the 23S rRNA K02909 - - 0.0000000000000000000000006636 108.0
HFD2_k127_4002770_23 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000304 81.0
HFD2_k127_4002770_25 - - - - 0.000000001104 70.0
HFD2_k127_4002770_3 KaiC K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009702 518.0
HFD2_k127_4002770_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005196 480.0
HFD2_k127_4002770_5 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 427.0
HFD2_k127_4002770_6 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000557 408.0
HFD2_k127_4002770_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 359.0
HFD2_k127_4002770_8 Large family of predicted nucleotide-binding domains - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001952 288.0
HFD2_k127_4002770_9 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000309 267.0
HFD2_k127_403339_0 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000002697 184.0
HFD2_k127_403339_1 AAA domain - - - 0.00000000000000000000000000000000000002159 150.0
HFD2_k127_403339_2 CBS domain - - - 0.000000002275 67.0
HFD2_k127_403339_3 Phosphate-starvation-inducible E - - - 0.0000002848 59.0
HFD2_k127_4180813_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1621.0
HFD2_k127_4180813_1 Adenylate and Guanylate cyclase catalytic domain - - - 0.0 1036.0
HFD2_k127_4180813_10 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008923 402.0
HFD2_k127_4180813_11 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 382.0
HFD2_k127_4180813_12 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008787 329.0
HFD2_k127_4180813_13 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369,K13890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 309.0
HFD2_k127_4180813_14 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 320.0
HFD2_k127_4180813_15 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 301.0
HFD2_k127_4180813_16 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 296.0
HFD2_k127_4180813_17 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772,K03773 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000584 287.0
HFD2_k127_4180813_18 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004228 289.0
HFD2_k127_4180813_19 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000136 267.0
HFD2_k127_4180813_2 N-methylhydantoinase A acetone carboxylase, beta subunit K01469,K01473 - 3.5.2.14,3.5.2.9 4.42e-219 702.0
HFD2_k127_4180813_20 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004966 277.0
HFD2_k127_4180813_21 PFAM import inner membrane translocase, subunit Tim44 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001087 256.0
HFD2_k127_4180813_22 Nitrile hydratase beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000005691 241.0
HFD2_k127_4180813_23 Nitrile hydratase K01721 - 4.2.1.84 0.0000000000000000000000000000000000000000000000000000000000000000001557 243.0
HFD2_k127_4180813_24 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000003179 231.0
HFD2_k127_4180813_25 mandelate racemase muconate lactonizing K01781 - 5.1.2.2 0.000000000000000000000000000000000000000000000000000000000000006602 229.0
HFD2_k127_4180813_26 Protein of unknown function (DUF3047) - - - 0.00000000000000000000000000000000000000000000000000000000001401 224.0
HFD2_k127_4180813_27 MlaA lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000002619 219.0
HFD2_k127_4180813_28 ligase activity, forming nitrogen-metal bonds K02230 - 6.6.1.2 0.000000000000000000000000000000000000000000000001607 186.0
HFD2_k127_4180813_29 PFAM Cupin 2, conserved barrel - - - 0.000000000000000000000000000000000000000000009341 180.0
HFD2_k127_4180813_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006436 623.0
HFD2_k127_4180813_30 Tim44 - - - 0.00000000000000000000000000000000000000001145 166.0
HFD2_k127_4180813_31 Belongs to the peptidase S51 family K05995 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 0.00000000000000000000000000000000000001681 165.0
HFD2_k127_4180813_32 Haloacid dehalogenase-like hydrolase K01101 - 3.1.3.41 0.000000000000000000000000000000000002494 149.0
HFD2_k127_4180813_33 - - - - 0.000000000000000000000000000000000003179 147.0
HFD2_k127_4180813_34 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000009889 148.0
HFD2_k127_4180813_35 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000006622 126.0
HFD2_k127_4180813_36 Trypsin-like peptidase domain - - - 0.0000000000000000000000000002122 131.0
HFD2_k127_4180813_37 Nitrile hydratase beta subunit - - - 0.00000000000000000007037 101.0
HFD2_k127_4180813_38 SNARE associated Golgi protein K03975 - - 0.000000000000000006983 98.0
HFD2_k127_4180813_39 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078,K05553 - - 0.00000000000000005664 88.0
HFD2_k127_4180813_4 N-methylhydantoinase B acetone carboxylase alpha subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 608.0
HFD2_k127_4180813_40 PFAM Cyclic nucleotide-binding K03321,K10914 - - 0.00000000001233 70.0
HFD2_k127_4180813_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 544.0
HFD2_k127_4180813_6 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 478.0
HFD2_k127_4180813_7 FAD dependent oxidoreductase K00109,K15736 - 1.1.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 472.0
HFD2_k127_4180813_8 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 470.0
HFD2_k127_4180813_9 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 410.0
HFD2_k127_4252282_0 ABC-type dipeptide transport system periplasmic component K02035 - - 1.932e-269 836.0
HFD2_k127_4252282_1 (ABC) transporter K15738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 601.0
HFD2_k127_4252282_2 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 458.0
HFD2_k127_4252282_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 454.0
HFD2_k127_4252282_4 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 388.0
HFD2_k127_4252282_5 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006353 370.0
HFD2_k127_4252282_6 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 383.0
HFD2_k127_4252282_7 Bacterial transferase hexapeptide (six repeats) K00640 GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016053,GO:0016054,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000001478 277.0
HFD2_k127_4252282_8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE - - - 0.00000000000000000000002607 104.0
HFD2_k127_4288930_0 Histidine kinase-like ATPase domain - - - 1.024e-230 749.0
HFD2_k127_4288930_1 FAD dependent oxidoreductase - - - 1.112e-215 684.0
HFD2_k127_4288930_10 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000001036 217.0
HFD2_k127_4288930_11 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000001842 223.0
HFD2_k127_4288930_12 PFAM ATP-binding region, ATPase domain protein K17752 - 2.7.11.1 0.0000000000000000000000000000000000000000000001823 171.0
HFD2_k127_4288930_13 transporter antisigma-factor antagonist STAS K17762 - - 0.0000000000000000000000000000000000000000000001991 171.0
HFD2_k127_4288930_14 Hydrogenase 4 membrane K12140 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000003755 158.0
HFD2_k127_4288930_2 NADH dehydrogenase (ubiquinone) activity K14089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 535.0
HFD2_k127_4288930_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006735 515.0
HFD2_k127_4288930_4 Proton-conducting membrane transporter K12137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 505.0
HFD2_k127_4288930_5 Proton-conducting membrane transporter K12141 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033554,GO:0044425,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 420.0
HFD2_k127_4288930_6 RsbT co-antagonist protein rsbRD N-terminal domain K17763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 327.0
HFD2_k127_4288930_7 NADH dehydrogenase K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 346.0
HFD2_k127_4288930_8 Stage II sporulation protein E - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 319.0
HFD2_k127_4288930_9 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000152 236.0
HFD2_k127_4331747_0 xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 2.191e-263 834.0
HFD2_k127_4331747_1 Ring hydroxylating alpha subunit (catalytic domain) K08689 - 1.14.12.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 536.0
HFD2_k127_4331747_10 ferredoxin-thioredoxin reductase activity K17892 GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015979,GO:0016491,GO:0016730,GO:0022900,GO:0030385,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 1.8.7.2 0.0000000000000000000000000000000000000000000000000000001007 198.0
HFD2_k127_4331747_11 [2Fe-2S] binding domain - - - 0.00000000000000000000000000000000000000000000000000004296 205.0
HFD2_k127_4331747_12 Ring hydroxylating beta subunit K15750 - 1.14.12.18 0.00000000000000000000000000000000000000000000000001948 202.0
HFD2_k127_4331747_13 IMP dehydrogenase activity K04767 - - 0.000000000000000000000003315 109.0
HFD2_k127_4331747_14 Glutaredoxin - - - 0.000000000002093 68.0
HFD2_k127_4331747_15 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000007225 64.0
HFD2_k127_4331747_2 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 498.0
HFD2_k127_4331747_3 C-terminal, D2-small domain, of ClpB protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 470.0
HFD2_k127_4331747_4 Nitrile hydratase, alpha chain K01721 - 4.2.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 370.0
HFD2_k127_4331747_5 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 342.0
HFD2_k127_4331747_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 306.0
HFD2_k127_4331747_7 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001387 270.0
HFD2_k127_4331747_8 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003123 256.0
HFD2_k127_4331747_9 Nitrile hydratase beta subunit - - - 0.00000000000000000000000000000000000000000000000000000000001324 209.0
HFD2_k127_437454_0 Acetamidase formamidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 306.0
HFD2_k127_437454_1 Adenylate cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006622 291.0
HFD2_k127_437454_2 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000001044 242.0
HFD2_k127_437454_3 - - - - 0.0000000000000000000000000000000000004872 143.0
HFD2_k127_437454_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000004475 110.0
HFD2_k127_4386449_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 8.421e-207 651.0
HFD2_k127_4386449_1 PFAM SMP-30 Gluconolaconase K01053 - 3.1.1.17 1.535e-204 639.0
HFD2_k127_4386449_10 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 490.0
HFD2_k127_4386449_11 Methionine synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 482.0
HFD2_k127_4386449_12 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 475.0
HFD2_k127_4386449_13 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 383.0
HFD2_k127_4386449_14 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 339.0
HFD2_k127_4386449_15 heat shock protein binding K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 316.0
HFD2_k127_4386449_16 carbon monoxide dehydrogenase K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 326.0
HFD2_k127_4386449_17 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 314.0
HFD2_k127_4386449_18 PFAM PDZ domain (Also known as DHR or GLGF) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 308.0
HFD2_k127_4386449_19 Arsenical pump-driving ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 315.0
HFD2_k127_4386449_2 Amidohydrolase family K01485 - 3.5.4.1 6.193e-198 624.0
HFD2_k127_4386449_20 3-carboxyethylcatechol 2,3-dioxygenase activity K05713 - 1.13.11.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 296.0
HFD2_k127_4386449_21 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 293.0
HFD2_k127_4386449_22 Bifunctional DNA primase/polymerase, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004252 304.0
HFD2_k127_4386449_23 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 300.0
HFD2_k127_4386449_24 COG4177 ABC-type branched-chain amino acid transport system, permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005231 285.0
HFD2_k127_4386449_25 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001193 273.0
HFD2_k127_4386449_26 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000105 279.0
HFD2_k127_4386449_27 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002412 272.0
HFD2_k127_4386449_28 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000224 252.0
HFD2_k127_4386449_29 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003385 259.0
HFD2_k127_4386449_3 Heavy-metal-associated domain K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 629.0
HFD2_k127_4386449_30 carbohydrate transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005655 256.0
HFD2_k127_4386449_32 COGs COG3328 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000001273 244.0
HFD2_k127_4386449_33 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000002575 232.0
HFD2_k127_4386449_34 PFAM amidohydrolase 2 K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000922 234.0
HFD2_k127_4386449_35 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.0000000000000000000000000000000000000000000000000000000000002222 231.0
HFD2_k127_4386449_36 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000000000000000000000008313 228.0
HFD2_k127_4386449_37 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000001272 214.0
HFD2_k127_4386449_38 PFAM binding-protein-dependent transport systems inner membrane component K02025,K10237 - - 0.0000000000000000000000000000000000000000000000000000001077 207.0
HFD2_k127_4386449_39 TIM-barrel fold metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000000002367 205.0
HFD2_k127_4386449_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 632.0
HFD2_k127_4386449_40 ABC-type sugar transport system, permease component K02026,K17323 - - 0.0000000000000000000000000000000000000000000000000001185 207.0
HFD2_k127_4386449_41 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000000000000003609 194.0
HFD2_k127_4386449_42 Protein of unknown function (DUF1566) - - - 0.0000000000000000000000000000000000000000000001972 184.0
HFD2_k127_4386449_43 Destroys radicals which are normally produced within the cells and which are toxic to biological systems - - - 0.0000000000000000000000000000000000000000002113 165.0
HFD2_k127_4386449_44 Serine threonine protein kinase K08282 - 2.7.11.1 0.00000000000000000000000000000000000000003699 166.0
HFD2_k127_4386449_45 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000001102 169.0
HFD2_k127_4386449_46 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000002976 154.0
HFD2_k127_4386449_47 PFAM Rhomboid family protein - - - 0.0000000000000000000000000000000000003057 157.0
HFD2_k127_4386449_48 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000009524 138.0
HFD2_k127_4386449_49 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000001255 130.0
HFD2_k127_4386449_5 Xanthine dehydrogenase K03520 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 616.0
HFD2_k127_4386449_50 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000004661 130.0
HFD2_k127_4386449_51 methyltransferase - - - 0.00000000000000000000000000000194 130.0
HFD2_k127_4386449_52 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000002539 128.0
HFD2_k127_4386449_53 Gas vesicle synthesis protein GvpL/GvpF - - - 0.000000000000000000000000000006558 134.0
HFD2_k127_4386449_54 Integrase core domain K07497 - - 0.0000000000000000000000000000138 132.0
HFD2_k127_4386449_55 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000001618 115.0
HFD2_k127_4386449_56 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000002346 127.0
HFD2_k127_4386449_57 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure - - - 0.000000000000000000000000004045 114.0
HFD2_k127_4386449_58 Gas vesicle protein K - - - 0.00000000000000000000001997 108.0
HFD2_k127_4386449_59 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth - - - 0.00000000000000000000002095 104.0
HFD2_k127_4386449_6 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 550.0
HFD2_k127_4386449_60 acyl-CoA dehydrogenase K22027 - 1.14.13.235 0.00000000000000000116 94.0
HFD2_k127_4386449_61 ParE-like toxin of type II bacterial toxin-antitoxin system - - - 0.0000000000000002246 82.0
HFD2_k127_4386449_62 Pfam:Pyridox_oxidase - - - 0.000000000000000523 87.0
HFD2_k127_4386449_64 TIGRFAM Protein of - - - 0.000000000000001211 82.0
HFD2_k127_4386449_65 AMP-binding enzyme C-terminal domain K00666,K02182,K20034 - 6.2.1.44,6.2.1.48 0.000000000000001725 78.0
HFD2_k127_4386449_66 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000002078 80.0
HFD2_k127_4386449_68 transposition K07497 - - 0.000000000001423 71.0
HFD2_k127_4386449_69 Thioesterase superfamily - - - 0.000000000002422 79.0
HFD2_k127_4386449_7 Methionine synthase vitamin-B12 independent K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 554.0
HFD2_k127_4386449_70 Protein of unknown function (DUF664) - - - 0.00000000002599 75.0
HFD2_k127_4386449_71 Gas vesicle - - - 0.0000000002195 73.0
HFD2_k127_4386449_72 Uncharacterized ACR, COG1993 K09137 - - 0.000000004203 66.0
HFD2_k127_4386449_74 Domain of unknown function (DUF4442) - - - 0.000007821 58.0
HFD2_k127_4386449_75 Right handed beta helix region - - - 0.00001007 59.0
HFD2_k127_4386449_76 AsnC family K03719 - - 0.0005687 47.0
HFD2_k127_4386449_8 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000894 531.0
HFD2_k127_4386449_9 monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000681 518.0
HFD2_k127_439183_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 482.0
HFD2_k127_439183_1 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000005051 192.0
HFD2_k127_439183_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000003281 139.0
HFD2_k127_4392588_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1130.0
HFD2_k127_4392588_1 elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 593.0
HFD2_k127_4392588_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000001504 66.0
HFD2_k127_4392588_11 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000493 66.0
HFD2_k127_4392588_13 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000008285 58.0
HFD2_k127_4392588_14 Domain of unknown function (DUF4124) - - - 0.0009135 49.0
HFD2_k127_4392588_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008839 438.0
HFD2_k127_4392588_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 299.0
HFD2_k127_4392588_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004828 280.0
HFD2_k127_4392588_5 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000001809 224.0
HFD2_k127_4392588_6 Protein of unknown function (DUF3105) - - - 0.000000000000000000000000000000000000000000000873 173.0
HFD2_k127_4392588_7 ATP hydrolysis coupled proton transport - - - 0.000000000000000000000000000000000004199 156.0
HFD2_k127_4392588_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000108 119.0
HFD2_k127_4402075_0 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000007601 259.0
HFD2_k127_4402075_1 cyclic nucleotide binding K07058,K14266 - 1.14.19.9 0.0000000000000000000001334 101.0
HFD2_k127_4402075_2 helix_turn_helix, cAMP Regulatory protein K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.000000000003621 71.0
HFD2_k127_4419896_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 326.0
HFD2_k127_4419896_1 abc transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001493 254.0
HFD2_k127_4419896_2 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004765 265.0
HFD2_k127_4419896_3 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001334 246.0
HFD2_k127_4419896_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000008343 244.0
HFD2_k127_4419896_5 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000615 228.0
HFD2_k127_4419896_6 PFAM Cupin 2 conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000001082 190.0
HFD2_k127_4419896_7 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000002331 118.0
HFD2_k127_4449389_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 552.0
HFD2_k127_4449389_1 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 395.0
HFD2_k127_4449389_10 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000003037 160.0
HFD2_k127_4449389_11 Transcriptional - - - 0.000000000000000000000000000000000000006685 148.0
HFD2_k127_4449389_12 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.000000000000000000000000000000004897 146.0
HFD2_k127_4449389_13 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000002622 123.0
HFD2_k127_4449389_14 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000005343 73.0
HFD2_k127_4449389_15 Glycine-zipper domain - - - 0.000000000001244 76.0
HFD2_k127_4449389_16 -Thioesterase K01075 - 3.1.2.23 0.000000008995 64.0
HFD2_k127_4449389_18 - - - - 0.0000008643 60.0
HFD2_k127_4449389_19 Protein tyrosine kinase - - - 0.000005147 59.0
HFD2_k127_4449389_2 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 394.0
HFD2_k127_4449389_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 355.0
HFD2_k127_4449389_4 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001935 265.0
HFD2_k127_4449389_5 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001904 252.0
HFD2_k127_4449389_6 outer membrane porin, OprD family - - - 0.0000000000000000000000000000000000000000000000000000000000002321 229.0
HFD2_k127_4449389_7 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000001525 204.0
HFD2_k127_4449389_8 FR47-like protein K03829 - - 0.0000000000000000000000000000000000000000000000000000001878 198.0
HFD2_k127_4449389_9 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000002631 190.0
HFD2_k127_4460981_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 560.0
HFD2_k127_4460981_1 metal-dependent hydrolase of the TIM-barrel fold K07046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005403 500.0
HFD2_k127_4460981_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000005325 188.0
HFD2_k127_4460981_3 - - - - 0.0000000000000000000000000000000000000000000002872 179.0
HFD2_k127_4460981_4 COG2346, Truncated hemoglobins K06886 - - 0.00000000000000000000000000000000000000000008598 167.0
HFD2_k127_4460981_5 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.000000000000000000000000003004 120.0
HFD2_k127_4460981_6 Urease, gamma subunit K14048 - 3.5.1.5 0.00000000000000000000007317 107.0
HFD2_k127_4464019_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01584 - 4.1.1.19 0.0 1324.0
HFD2_k127_4464019_1 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0 1292.0
HFD2_k127_4464019_10 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 344.0
HFD2_k127_4464019_11 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 336.0
HFD2_k127_4464019_12 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 321.0
HFD2_k127_4464019_13 Biotin-lipoyl like K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002775 293.0
HFD2_k127_4464019_14 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005535 278.0
HFD2_k127_4464019_15 outer membrane porin, OprD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000545 250.0
HFD2_k127_4464019_16 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000001002 240.0
HFD2_k127_4464019_17 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000001558 222.0
HFD2_k127_4464019_18 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000007244 201.0
HFD2_k127_4464019_19 response regulator - - - 0.000000000000000000000000000000000000000000000000000001835 201.0
HFD2_k127_4464019_2 Aminotransferase class I and II K09758 - 4.1.1.12 3.927e-296 914.0
HFD2_k127_4464019_20 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000005757 179.0
HFD2_k127_4464019_21 - - - - 0.00000000000000000000000000000000000000002946 168.0
HFD2_k127_4464019_22 - - - - 0.000000000000000000000000000000006615 146.0
HFD2_k127_4464019_23 phosphorelay signal transduction system K14987 - - 0.0000000000000000000000000001121 119.0
HFD2_k127_4464019_24 Ion channel - - - 0.00000000000000000000000006845 124.0
HFD2_k127_4464019_25 Phospholipid methyltransferase - - - 0.0000000000000000008537 96.0
HFD2_k127_4464019_26 PFAM Integrase catalytic - - - 0.0000000008182 64.0
HFD2_k127_4464019_27 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000001119 67.0
HFD2_k127_4464019_28 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.0000007924 55.0
HFD2_k127_4464019_29 Integrase core domain - - - 0.000224 48.0
HFD2_k127_4464019_3 Predicted Permease Membrane Region K07085 - - 1.952e-267 832.0
HFD2_k127_4464019_4 Predicted Permease Membrane Region - - - 2.259e-242 760.0
HFD2_k127_4464019_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 481.0
HFD2_k127_4464019_6 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 494.0
HFD2_k127_4464019_7 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009219 416.0
HFD2_k127_4464019_8 Domain of unknown function (DUF4105) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 398.0
HFD2_k127_4464019_9 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007767 398.0
HFD2_k127_4466391_0 Belongs to the amidase family K01426 - 3.5.1.4 1.443e-250 782.0
HFD2_k127_4466391_1 MacB-like periplasmic core domain K02004 - - 1.218e-241 786.0
HFD2_k127_4466391_10 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 411.0
HFD2_k127_4466391_11 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 407.0
HFD2_k127_4466391_12 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 357.0
HFD2_k127_4466391_13 Isocitrate lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006713 353.0
HFD2_k127_4466391_14 Gamma-glutamyltranspeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000964 372.0
HFD2_k127_4466391_15 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000679 307.0
HFD2_k127_4466391_16 Branched-chain amino acid ATP-binding cassette transporter K01995,K11962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 322.0
HFD2_k127_4466391_17 Phosphoenolpyruvate phosphomutase K03417 - 4.1.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 297.0
HFD2_k127_4466391_18 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 304.0
HFD2_k127_4466391_19 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004721 277.0
HFD2_k127_4466391_2 SMART alpha amylase, catalytic sub domain K01187 - 3.2.1.20 2.978e-222 715.0
HFD2_k127_4466391_20 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001104 280.0
HFD2_k127_4466391_21 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007654 293.0
HFD2_k127_4466391_22 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001496 280.0
HFD2_k127_4466391_23 TIM-barrel fold metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003835 275.0
HFD2_k127_4466391_24 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 - 1.13.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000001864 245.0
HFD2_k127_4466391_25 PFAM MOSC domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000003961 239.0
HFD2_k127_4466391_26 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000000000000001264 222.0
HFD2_k127_4466391_27 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000001841 210.0
HFD2_k127_4466391_28 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000001207 192.0
HFD2_k127_4466391_29 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000006425 192.0
HFD2_k127_4466391_3 Periplasmic binding protein domain K01999 - - 3.31e-202 635.0
HFD2_k127_4466391_30 Phosphoesterase K07095 - - 0.0000000000000000000000000000000000000000000001283 173.0
HFD2_k127_4466391_31 PFAM 4-hydroxyphenylacetate 3-hydroxylase K00483 - 1.14.14.9 0.0000000000000000000000000000000000000001249 169.0
HFD2_k127_4466391_32 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000003163 157.0
HFD2_k127_4466391_33 cellulose binding - - - 0.00000000000000000000000000000002744 143.0
HFD2_k127_4466391_34 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.0000000000000000000007345 111.0
HFD2_k127_4466391_35 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000001563 94.0
HFD2_k127_4466391_36 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 0.000000000004608 74.0
HFD2_k127_4466391_37 PRC-barrel domain - - - 0.0000003482 61.0
HFD2_k127_4466391_38 periplasmic or secreted lipoprotein - - - 0.00000131 59.0
HFD2_k127_4466391_39 Protease prsW family - - - 0.00002134 51.0
HFD2_k127_4466391_4 FAD dependent oxidoreductase K13796 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 613.0
HFD2_k127_4466391_40 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00004446 49.0
HFD2_k127_4466391_5 FAD dependent oxidoreductase K13796 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 591.0
HFD2_k127_4466391_6 AMP-binding enzyme C-terminal domain K02182 - 6.2.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 581.0
HFD2_k127_4466391_7 His Kinase A (phosphoacceptor) domain K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 472.0
HFD2_k127_4466391_8 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 413.0
HFD2_k127_4466391_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006261 415.0
HFD2_k127_4481352_0 Biotin carboxylase C-terminal domain - - - 0.0 1328.0
HFD2_k127_4481352_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 5.914e-205 657.0
HFD2_k127_4481352_10 Peptidase, M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007879 431.0
HFD2_k127_4481352_11 cell redox homeostasis K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009888 405.0
HFD2_k127_4481352_12 serine-type endopeptidase activity K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 303.0
HFD2_k127_4481352_13 Alpha beta hydrolase K14731 - 3.1.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 304.0
HFD2_k127_4481352_14 PFAM Phosphomethylpyrimidine kinase type-1 K00941,K14153 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008028 288.0
HFD2_k127_4481352_15 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005605 286.0
HFD2_k127_4481352_16 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005702 289.0
HFD2_k127_4481352_17 Alanine-glyoxylate amino-transferase K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003729 271.0
HFD2_k127_4481352_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002594 253.0
HFD2_k127_4481352_19 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009337 248.0
HFD2_k127_4481352_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 579.0
HFD2_k127_4481352_20 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000001147 250.0
HFD2_k127_4481352_21 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000005702 235.0
HFD2_k127_4481352_22 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000006431 239.0
HFD2_k127_4481352_23 Inositol monophosphatase - - - 0.0000000000000000000000000000000000000000000000000000002532 202.0
HFD2_k127_4481352_24 decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000003437 208.0
HFD2_k127_4481352_25 NADPH-dependent FMN reductase K00299 - 1.5.1.38 0.000000000000000000000000000000000000000000000002883 188.0
HFD2_k127_4481352_26 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000001342 170.0
HFD2_k127_4481352_27 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000007026 136.0
HFD2_k127_4481352_28 - - - - 0.000000000000000000000000000000001113 138.0
HFD2_k127_4481352_29 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000001472 140.0
HFD2_k127_4481352_3 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 560.0
HFD2_k127_4481352_30 Methyltransferase domain - - - 0.0000000000000000000000000000002189 143.0
HFD2_k127_4481352_31 membrane transporter protein K07090 - - 0.000000000000000002031 94.0
HFD2_k127_4481352_32 response regulator - - - 0.0000000000000007758 83.0
HFD2_k127_4481352_33 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.000000003148 62.0
HFD2_k127_4481352_34 - - - - 0.00000004229 64.0
HFD2_k127_4481352_4 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 528.0
HFD2_k127_4481352_5 III protein, CoA-transferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007621 524.0
HFD2_k127_4481352_6 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 517.0
HFD2_k127_4481352_7 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K04091 - 1.14.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 473.0
HFD2_k127_4481352_8 Amidohydrolase family K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006612 442.0
HFD2_k127_4481352_9 Adenylosuccinate lyase C-terminus K01756,K01857 - 4.3.2.2,5.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 416.0
HFD2_k127_4503956_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 8.238e-198 631.0
HFD2_k127_4503956_1 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 608.0
HFD2_k127_4503956_10 Acetyltransferase (GNAT) domain - - - 0.00000000000000000009906 93.0
HFD2_k127_4503956_11 Belongs to the glycosyl hydrolase 2 family - - - 0.000000000000000216 95.0
HFD2_k127_4503956_12 - - - - 0.00000000000001189 77.0
HFD2_k127_4503956_13 Evidence 5 No homology to any previously reported sequences K03088 - - 0.0000001154 66.0
HFD2_k127_4503956_14 Amidohydrolase family - - - 0.0000003027 63.0
HFD2_k127_4503956_15 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000001903 63.0
HFD2_k127_4503956_16 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0003034 46.0
HFD2_k127_4503956_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007274 531.0
HFD2_k127_4503956_3 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006314 468.0
HFD2_k127_4503956_4 Major facilitator K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 362.0
HFD2_k127_4503956_5 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 350.0
HFD2_k127_4503956_6 Activator of Hsp90 ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002238 247.0
HFD2_k127_4503956_7 - - - - 0.0000000000000000000000000000000000000000000000000000317 204.0
HFD2_k127_4503956_8 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000177 179.0
HFD2_k127_4503956_9 - K03561,K12287 - - 0.000000000000000000001549 112.0
HFD2_k127_4504448_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005271 561.0
HFD2_k127_4555738_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1305.0
HFD2_k127_4555738_1 56kDa selenium binding protein (SBP56) K17285 - - 3.666e-266 824.0
HFD2_k127_4555738_10 FMN-dependent dehydrogenase K16422 - 1.1.3.46 0.000000000000000000000000000000000000000000000000000000000000000000000000001428 269.0
HFD2_k127_4555738_11 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002128 255.0
HFD2_k127_4555738_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000008315 237.0
HFD2_k127_4555738_13 Protein of unknown function (DUF1499) - - - 0.00000000000000000000000000000000000000000000000000002126 196.0
HFD2_k127_4555738_14 PFAM Cupin 2 conserved barrel domain protein K21700 - - 0.00000000000000000000000000005773 135.0
HFD2_k127_4555738_15 Chromate transporter K07240 - - 0.00000000000000000000000003719 122.0
HFD2_k127_4555738_16 hydrolase, CocE NonD family K06978 - - 0.00000000000000000002004 93.0
HFD2_k127_4555738_17 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000007452 84.0
HFD2_k127_4555738_18 PFAM Chromate transporter K07240 - - 0.000000000000007659 81.0
HFD2_k127_4555738_19 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000005491 63.0
HFD2_k127_4555738_2 Adenylate cyclase - - - 5.373e-239 757.0
HFD2_k127_4555738_20 Protoglobin - - - 0.00003883 53.0
HFD2_k127_4555738_21 acetyltransferase - - - 0.000686 44.0
HFD2_k127_4555738_3 Luciferase-like monooxygenase - - - 6.913e-194 614.0
HFD2_k127_4555738_4 Berberine and berberine like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 646.0
HFD2_k127_4555738_5 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 552.0
HFD2_k127_4555738_6 PFAM alanine racemase domain protein K20757 - 4.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 375.0
HFD2_k127_4555738_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 352.0
HFD2_k127_4555738_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 327.0
HFD2_k127_4555738_9 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 308.0
HFD2_k127_4556470_0 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 545.0
HFD2_k127_4556470_1 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 539.0
HFD2_k127_4556470_10 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 - 1.13.11.6 0.000000000000000000000000000000000000000000000000002152 203.0
HFD2_k127_4556470_11 Major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000009565 139.0
HFD2_k127_4556470_13 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000007268 82.0
HFD2_k127_4556470_14 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000003118 70.0
HFD2_k127_4556470_16 - - - - 0.000000001351 61.0
HFD2_k127_4556470_17 Protein conserved in bacteria - - - 0.00000002184 66.0
HFD2_k127_4556470_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00066 - 1.1.1.132 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 456.0
HFD2_k127_4556470_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 368.0
HFD2_k127_4556470_4 Belongs to the enoyl-CoA hydratase isomerase family K08299 - 4.2.1.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009961 302.0
HFD2_k127_4556470_5 acyl-CoA dehydrogenase K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 308.0
HFD2_k127_4556470_6 Heparinase II/III N-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002137 297.0
HFD2_k127_4556470_7 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005357 291.0
HFD2_k127_4556470_8 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003391 279.0
HFD2_k127_4556470_9 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002151 270.0
HFD2_k127_4569966_0 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 376.0
HFD2_k127_4569966_1 Ndr family - - - 0.00000000000000000000000000000000000000000000000000000000004548 214.0
HFD2_k127_4569966_2 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000004125 167.0
HFD2_k127_4569966_3 Iron-sulfur cluster assembly protein - - - 0.00000000000000000000000000000005824 133.0
HFD2_k127_4569966_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000006248 72.0
HFD2_k127_4569966_5 Protein of unknown function, DUF393 - - - 0.00000000009468 68.0
HFD2_k127_4582701_0 AMP-binding enzyme K15868 - 6.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 585.0
HFD2_k127_4582701_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 560.0
HFD2_k127_4582701_10 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000256 300.0
HFD2_k127_4582701_11 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005204 284.0
HFD2_k127_4582701_12 PFAM extracellular solute-binding protein family 1 K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001309 281.0
HFD2_k127_4582701_13 Pfam:Pyridox_oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000149 254.0
HFD2_k127_4582701_14 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007504 260.0
HFD2_k127_4582701_15 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000005729 243.0
HFD2_k127_4582701_16 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000004379 226.0
HFD2_k127_4582701_17 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.00000000000000000000000000000000000000000000000000000001285 203.0
HFD2_k127_4582701_18 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000001137 215.0
HFD2_k127_4582701_19 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000009711 195.0
HFD2_k127_4582701_2 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 548.0
HFD2_k127_4582701_20 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000002895 182.0
HFD2_k127_4582701_21 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000139 139.0
HFD2_k127_4582701_23 membrane K08983 - - 0.0000000000000000000000000000002995 132.0
HFD2_k127_4582701_24 Glyoxalase-like domain K08234 - - 0.000000000000000000000000000001039 128.0
HFD2_k127_4582701_25 Thioredoxin - - - 0.00000000000000000000001922 114.0
HFD2_k127_4582701_26 Polysaccharide biosynthesis protein - - - 0.00000000000000000001983 104.0
HFD2_k127_4582701_27 - - - - 0.000000000005369 71.0
HFD2_k127_4582701_28 protein conserved in bacteria K21470 - - 0.0000002746 53.0
HFD2_k127_4582701_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007888 507.0
HFD2_k127_4582701_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 376.0
HFD2_k127_4582701_5 Polyprenyl synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 344.0
HFD2_k127_4582701_6 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 310.0
HFD2_k127_4582701_7 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 314.0
HFD2_k127_4582701_8 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 303.0
HFD2_k127_4582701_9 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 304.0
HFD2_k127_4588075_0 PFAM glycosyl transferase family 35 K00688 - 2.4.1.1 0.0 1102.0
HFD2_k127_4588075_1 E1-E2 ATPase K01531 - 3.6.3.2 2.275e-227 721.0
HFD2_k127_4588075_2 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 521.0
HFD2_k127_4588075_3 Bacterial capsule synthesis protein PGA_cap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 446.0
HFD2_k127_4588075_4 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000005146 264.0
HFD2_k127_4588075_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000001258 225.0
HFD2_k127_4588075_6 Glycine-zipper domain - - - 0.0000000000000000000000000000003321 134.0
HFD2_k127_4588075_7 - - - - 0.000000000000001748 81.0
HFD2_k127_4588075_8 oxidoreductase - - - 0.0001527 46.0
HFD2_k127_4600154_0 4-hydroxyphenylacetate K00483 - 1.14.14.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 515.0
HFD2_k127_4600154_1 peptidase dimerisation domain protein K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 472.0
HFD2_k127_4600154_10 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000003079 235.0
HFD2_k127_4600154_11 Acyl-CoA thioesterase K10805 - - 0.000000000000000000000000000000000000000005583 158.0
HFD2_k127_4600154_12 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.0000000000000000000000000000008314 129.0
HFD2_k127_4600154_13 Amidohydrolase family - - - 0.000000000000000000000000327 111.0
HFD2_k127_4600154_15 amidohydrolase - - - 0.0000000001914 63.0
HFD2_k127_4600154_2 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 390.0
HFD2_k127_4600154_3 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007752 359.0
HFD2_k127_4600154_4 Receptor family ligand binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 304.0
HFD2_k127_4600154_5 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006562 282.0
HFD2_k127_4600154_6 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009956 284.0
HFD2_k127_4600154_7 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001631 274.0
HFD2_k127_4600154_8 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000001343 258.0
HFD2_k127_4600154_9 amidohydrolase K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002297 263.0
HFD2_k127_4602287_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 609.0
HFD2_k127_4602287_1 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 489.0
HFD2_k127_4602287_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 370.0
HFD2_k127_4602287_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005466 280.0
HFD2_k127_4602287_4 short-chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001323 262.0
HFD2_k127_4605711_0 UDP-galactopyranose mutase K01854 - 5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 445.0
HFD2_k127_4605711_1 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004785 406.0
HFD2_k127_4605711_2 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 334.0
HFD2_k127_4605711_3 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000001647 186.0
HFD2_k127_4605711_5 SMART Prolyl 4-hydroxylase, alpha subunit - - - 0.00000000000000000000000000000001429 145.0
HFD2_k127_4605711_6 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 0.00000000000000000000000000004622 122.0
HFD2_k127_4605711_7 Glycosyl transferase, family 2 - - - 0.0000000000000000000000002074 123.0
HFD2_k127_4605711_8 Domain of unknown function (DUF1330) - - - 0.0000000000000000000009722 98.0
HFD2_k127_4605711_9 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000008801 88.0
HFD2_k127_4620172_0 Reverse transcriptase (RNA-dependent DNA polymerase) K00986,K15342 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 520.0
HFD2_k127_4620172_1 biosynthesis protein E K06139 GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 492.0
HFD2_k127_4620172_10 Predicted permease K07089 - - 0.0000000000000000000000000000000000000165 164.0
HFD2_k127_4620172_11 Hydantoinase/oxoprolinase K01469,K01473 - 3.5.2.14,3.5.2.9 0.000000000000000000000000000000001165 135.0
HFD2_k127_4620172_12 amino acid transport K02030 - - 0.00000000000000000000000000007874 134.0
HFD2_k127_4620172_13 methylamine metabolic process K03885,K16937 - 1.6.99.3,1.8.5.2 0.00000000000000000000000008021 113.0
HFD2_k127_4620172_14 biosynthesis protein E K06139 GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - 0.000000000000101 78.0
HFD2_k127_4620172_15 Hydantoinase/oxoprolinase K01469,K01473 - 3.5.2.14,3.5.2.9 0.0000000000008182 74.0
HFD2_k127_4620172_2 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 384.0
HFD2_k127_4620172_3 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 348.0
HFD2_k127_4620172_4 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 290.0
HFD2_k127_4620172_5 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007979 277.0
HFD2_k127_4620172_6 PQQ-dependent catabolism-associated beta-propeller protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008614 277.0
HFD2_k127_4620172_7 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001087 274.0
HFD2_k127_4620172_8 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000009999 230.0
HFD2_k127_4620172_9 Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000001045 221.0
HFD2_k127_4620186_0 Phosphotriesterase K07048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 312.0
HFD2_k127_4620186_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000141 219.0
HFD2_k127_4620186_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000006746 124.0
HFD2_k127_4620186_3 DDE superfamily endonuclease - - - 0.0000000000000000000000001923 107.0
HFD2_k127_4659435_0 Hydantoinase/oxoprolinase K01469,K01473 - 3.5.2.14,3.5.2.9 9.586e-268 837.0
HFD2_k127_4659435_1 Hydantoinase B/oxoprolinase - - - 4.642e-256 806.0
HFD2_k127_4659435_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.000000002803 59.0
HFD2_k127_4668796_0 xanthine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 607.0
HFD2_k127_4668796_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000002249 116.0
HFD2_k127_4672270_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 5.315e-268 844.0
HFD2_k127_4672270_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.534e-249 789.0
HFD2_k127_4672270_10 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009182 552.0
HFD2_k127_4672270_100 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000004008 187.0
HFD2_k127_4672270_101 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.00000000000000000000000000000000000000000001531 176.0
HFD2_k127_4672270_102 Ribosomal protein S9/S16 K02996 - - 0.00000000000000000000000000000000000000000009493 171.0
HFD2_k127_4672270_103 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.000000000000000000000000000000000000000002051 164.0
HFD2_k127_4672270_104 Sugar (and other) transporter K08161 - - 0.000000000000000000000000000000000000000009793 169.0
HFD2_k127_4672270_105 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000004513 164.0
HFD2_k127_4672270_106 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000001489 153.0
HFD2_k127_4672270_107 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000000000002973 153.0
HFD2_k127_4672270_108 Extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000001347 145.0
HFD2_k127_4672270_109 NUDIX domain - - - 0.000000000000000000000000000000001224 137.0
HFD2_k127_4672270_11 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 542.0
HFD2_k127_4672270_110 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000002092 148.0
HFD2_k127_4672270_111 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000000000229 140.0
HFD2_k127_4672270_112 PFAM MaoC domain protein dehydratase K17865 - 4.2.1.55 0.000000000000000000000000000000003247 143.0
HFD2_k127_4672270_113 O-linked GlcNAc transferase - - - 0.000000000000000000000000000000003302 140.0
HFD2_k127_4672270_114 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000001645 129.0
HFD2_k127_4672270_115 EamA-like transporter family - - - 0.00000000000000000000000000000001666 138.0
HFD2_k127_4672270_116 PFAM MaoC like domain - - - 0.00000000000000000000000000000003324 146.0
HFD2_k127_4672270_117 DinB superfamily K07552 - - 0.000000000000000000000000000000168 129.0
HFD2_k127_4672270_118 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000007182 128.0
HFD2_k127_4672270_119 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04099,K04101 - 1.13.11.57,1.13.11.8 0.00000000000000000000000000007907 136.0
HFD2_k127_4672270_12 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 541.0
HFD2_k127_4672270_120 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000001574 119.0
HFD2_k127_4672270_121 Smr domain - - - 0.000000000000000000000000002368 126.0
HFD2_k127_4672270_122 PFAM PHA accumulation regulator DNA-binding protein - - - 0.0000000000000000000000004197 110.0
HFD2_k127_4672270_123 SnoaL-like domain - - - 0.00000000000000000000001143 105.0
HFD2_k127_4672270_124 membrane K02451,K03832 - - 0.00000000000000000000002057 112.0
HFD2_k127_4672270_125 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000003485 97.0
HFD2_k127_4672270_126 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000005488 89.0
HFD2_k127_4672270_127 Acetyl propionyl-CoA carboxylase alpha subunit K02160 - - 0.00000000000000005617 84.0
HFD2_k127_4672270_128 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000002334 89.0
HFD2_k127_4672270_129 Thioredoxin-like - - - 0.000000000000003353 79.0
HFD2_k127_4672270_13 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 505.0
HFD2_k127_4672270_130 Cytidylyltransferase K00983,K18431 - 2.7.7.43,2.7.7.82 0.00000000000003686 78.0
HFD2_k127_4672270_131 Protein of unknown function (DUF455) - - - 0.0000000000005237 82.0
HFD2_k127_4672270_132 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000009729 78.0
HFD2_k127_4672270_133 Protein of unknown function (DUF448) K07742 - - 0.00000000002112 71.0
HFD2_k127_4672270_134 Protein of unknown function (DUF1232) - - - 0.00000000003658 77.0
HFD2_k127_4672270_135 Belongs to the UPF0312 family - - - 0.0000000001268 70.0
HFD2_k127_4672270_136 polyhydroxyalkanoic acid synthase, PhaR subunit - - - 0.0000000002737 73.0
HFD2_k127_4672270_137 Redoxin K03564 - 1.11.1.15 0.000000001809 63.0
HFD2_k127_4672270_138 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000001396 65.0
HFD2_k127_4672270_139 - - - - 0.00001333 56.0
HFD2_k127_4672270_14 PFAM extracellular solute-binding protein family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 514.0
HFD2_k127_4672270_140 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0001228 47.0
HFD2_k127_4672270_141 Redoxin domain protein - - - 0.0008715 51.0
HFD2_k127_4672270_15 Domain of unknown function (DUF4445) K04755,K08952,K08953,K08954 GO:0005575,GO:0005622,GO:0005623,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0046858 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 507.0
HFD2_k127_4672270_16 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 491.0
HFD2_k127_4672270_17 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008596 473.0
HFD2_k127_4672270_18 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 474.0
HFD2_k127_4672270_19 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 479.0
HFD2_k127_4672270_2 Peptidoglycan-binding domain 1 protein K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 - 2.218e-216 686.0
HFD2_k127_4672270_20 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 465.0
HFD2_k127_4672270_21 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 487.0
HFD2_k127_4672270_22 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 430.0
HFD2_k127_4672270_23 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 412.0
HFD2_k127_4672270_24 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008373 426.0
HFD2_k127_4672270_25 N-terminal TM domain of oligopeptide transport permease C K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 405.0
HFD2_k127_4672270_26 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 409.0
HFD2_k127_4672270_27 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 401.0
HFD2_k127_4672270_28 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 383.0
HFD2_k127_4672270_29 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000995 387.0
HFD2_k127_4672270_3 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.981e-200 653.0
HFD2_k127_4672270_30 PFAM SMP-30 Gluconolaconase K08685 - 1.4.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 386.0
HFD2_k127_4672270_31 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007601 388.0
HFD2_k127_4672270_32 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009845 382.0
HFD2_k127_4672270_33 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 364.0
HFD2_k127_4672270_34 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 368.0
HFD2_k127_4672270_35 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 357.0
HFD2_k127_4672270_36 Alanine-glyoxylate amino-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009466 364.0
HFD2_k127_4672270_37 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 362.0
HFD2_k127_4672270_38 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 349.0
HFD2_k127_4672270_39 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 344.0
HFD2_k127_4672270_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000754 619.0
HFD2_k127_4672270_40 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 342.0
HFD2_k127_4672270_41 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 336.0
HFD2_k127_4672270_42 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 333.0
HFD2_k127_4672270_43 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 345.0
HFD2_k127_4672270_44 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 326.0
HFD2_k127_4672270_45 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 329.0
HFD2_k127_4672270_46 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 318.0
HFD2_k127_4672270_47 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 315.0
HFD2_k127_4672270_48 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 303.0
HFD2_k127_4672270_49 Sir2 family K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 310.0
HFD2_k127_4672270_5 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 621.0
HFD2_k127_4672270_50 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 310.0
HFD2_k127_4672270_51 PFAM binding-protein-dependent transport systems inner membrane component K02033,K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 298.0
HFD2_k127_4672270_52 ABC transporter K09689,K09691 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 290.0
HFD2_k127_4672270_53 LAO AO transport system K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 299.0
HFD2_k127_4672270_54 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 288.0
HFD2_k127_4672270_55 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001326 285.0
HFD2_k127_4672270_56 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001425 286.0
HFD2_k127_4672270_57 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005075 282.0
HFD2_k127_4672270_58 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002564 279.0
HFD2_k127_4672270_59 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000002605 284.0
HFD2_k127_4672270_6 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 599.0
HFD2_k127_4672270_60 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004909 258.0
HFD2_k127_4672270_61 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000001788 246.0
HFD2_k127_4672270_62 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000387 237.0
HFD2_k127_4672270_63 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000004012 241.0
HFD2_k127_4672270_64 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000006567 236.0
HFD2_k127_4672270_65 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000001983 235.0
HFD2_k127_4672270_66 DHH family K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000001146 241.0
HFD2_k127_4672270_67 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000015 231.0
HFD2_k127_4672270_68 Glucose dehydrogenase C-terminus K00008,K00060 - 1.1.1.103,1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000008726 235.0
HFD2_k127_4672270_69 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000001534 245.0
HFD2_k127_4672270_7 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 GO:0003674,GO:0003824,GO:0004321,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009268,GO:0009628,GO:0010447,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051704,GO:0071944 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 603.0
HFD2_k127_4672270_70 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004845 223.0
HFD2_k127_4672270_71 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000005891 243.0
HFD2_k127_4672270_72 - - - - 0.000000000000000000000000000000000000000000000000000000000000002257 231.0
HFD2_k127_4672270_73 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000003496 233.0
HFD2_k127_4672270_74 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000001033 237.0
HFD2_k127_4672270_75 Transport permease protein K09688,K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000131 224.0
HFD2_k127_4672270_76 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000001454 226.0
HFD2_k127_4672270_77 COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000000002754 240.0
HFD2_k127_4672270_78 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000008399 218.0
HFD2_k127_4672270_79 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000005425 228.0
HFD2_k127_4672270_8 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 606.0
HFD2_k127_4672270_80 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000001684 227.0
HFD2_k127_4672270_82 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000003915 238.0
HFD2_k127_4672270_83 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000192 220.0
HFD2_k127_4672270_84 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000001166 212.0
HFD2_k127_4672270_85 Belongs to the CinA family - - - 0.000000000000000000000000000000000000000000000000000000003339 209.0
HFD2_k127_4672270_86 transport, permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000135 202.0
HFD2_k127_4672270_87 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000002034 196.0
HFD2_k127_4672270_88 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000001774 191.0
HFD2_k127_4672270_89 - - - - 0.000000000000000000000000000000000000000000000000001749 188.0
HFD2_k127_4672270_9 Glycosyltransferase, group 2 family protein K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 595.0
HFD2_k127_4672270_90 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000003172 192.0
HFD2_k127_4672270_91 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000006425 200.0
HFD2_k127_4672270_92 response to pH - - - 0.0000000000000000000000000000000000000000000000000716 183.0
HFD2_k127_4672270_93 NAD dependent epimerase/dehydratase family K00023,K00059 - 1.1.1.100,1.1.1.36 0.0000000000000000000000000000000000000000000000001338 181.0
HFD2_k127_4672270_94 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000002828 191.0
HFD2_k127_4672270_95 Fumarylacetoacetate (FAA) hydrolase family K02554 - 4.2.1.80 0.00000000000000000000000000000000000000000000001545 181.0
HFD2_k127_4672270_96 membrane - - - 0.0000000000000000000000000000000000000000000000282 186.0
HFD2_k127_4672270_97 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000001083 186.0
HFD2_k127_4672270_98 dehydratase - - - 0.000000000000000000000000000000000000000000001327 178.0
HFD2_k127_4672270_99 YsiA-like protein, C-terminal region K13770 - - 0.000000000000000000000000000000000000000000001512 172.0
HFD2_k127_4712195_0 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 394.0
HFD2_k127_4712195_1 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 357.0
HFD2_k127_4712195_10 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000003784 219.0
HFD2_k127_4712195_11 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000001806 211.0
HFD2_k127_4712195_12 YCII-related domain - - - 0.000000000000000000000000000000001288 134.0
HFD2_k127_4712195_13 PFAM N-formylglutamate amidohydrolase - - - 0.000000000000000000008264 103.0
HFD2_k127_4712195_14 coenzyme F420 binding - - - 0.00000000000000008424 86.0
HFD2_k127_4712195_2 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008376 330.0
HFD2_k127_4712195_3 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 336.0
HFD2_k127_4712195_4 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 324.0
HFD2_k127_4712195_5 EH COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009653 287.0
HFD2_k127_4712195_6 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002256 289.0
HFD2_k127_4712195_7 P-loop containing region of AAA domain K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006132 288.0
HFD2_k127_4712195_8 PFAM luciferase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000008131 241.0
HFD2_k127_4712195_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000006866 220.0
HFD2_k127_4720296_0 Glycosyl hydrolase family 3 C-terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 403.0
HFD2_k127_4720296_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005994 261.0
HFD2_k127_4720296_2 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000003838 119.0
HFD2_k127_4755234_0 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000004138 214.0
HFD2_k127_4755234_1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000002225 189.0
HFD2_k127_4755234_2 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000004335 152.0
HFD2_k127_4766590_0 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.000000000000000000000000000000000000000000000000000000007918 208.0
HFD2_k127_4766590_1 NUDIX domain - - - 0.000000000000000000000000002653 120.0
HFD2_k127_4766590_2 Glycosyl transferase family 21 K00721 - 2.4.1.83 0.000000000001702 73.0
HFD2_k127_477030_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 526.0
HFD2_k127_477030_1 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 303.0
HFD2_k127_477030_2 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000000000000000000003641 199.0
HFD2_k127_477030_3 Peptidase family M28 - - - 0.000000000002017 76.0
HFD2_k127_477030_4 OmpA family K03286 - - 0.0000000645 65.0
HFD2_k127_4795412_0 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006777 432.0
HFD2_k127_4795412_1 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000005332 224.0
HFD2_k127_4795412_2 acetyltransferase - - - 0.0000000000000000000000000000000000000000001045 173.0
HFD2_k127_4795412_3 Protein of Unknown function (DUF2784) - - - 0.00000000000000000000000000000000000005584 145.0
HFD2_k127_4797895_0 Acyl-CoA dehydrogenase, middle domain K00249 - 1.3.8.7 4.476e-275 856.0
HFD2_k127_4797895_1 dihydroxy-acid dehydratase activity K01687 - 4.2.1.9 4.108e-263 823.0
HFD2_k127_4797895_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 1.346e-254 797.0
HFD2_k127_4797895_3 von Willebrand factor (vWF) type A domain - - - 8.469e-221 703.0
HFD2_k127_4797895_4 Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005666 604.0
HFD2_k127_4797895_5 non-haem dioxygenase in morphine synthesis N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 407.0
HFD2_k127_4797895_6 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000297 267.0
HFD2_k127_4797895_7 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002617 254.0
HFD2_k127_4797895_8 Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells K03649 - 3.2.2.28 0.000000000000000000000000000000000000000000000001838 182.0
HFD2_k127_4801379_0 SNF2 family N-terminal domain - - - 3.335e-309 977.0
HFD2_k127_4801379_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000002881 203.0
HFD2_k127_4801379_2 SNARE associated Golgi protein - - - 0.00000000000000000000000000001835 126.0
HFD2_k127_4801379_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000006286 102.0
HFD2_k127_4801446_0 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 560.0
HFD2_k127_4801446_1 PFAM ABC transporter related K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 345.0
HFD2_k127_4801446_2 Glutamate aspartate transport system permease protein GltJ K02029,K10003 - - 0.0000000000000000000000000000000000000000000000000000000000001127 221.0
HFD2_k127_4801446_3 Bacterial periplasmic substrate-binding proteins K02030,K10001 - - 0.00000000000000000000000000000000000000000000000000004037 207.0
HFD2_k127_4801446_4 PFAM binding-protein-dependent transport systems inner membrane component K02029,K10002 - - 0.0000000000000000000000000000000000000000000000000000448 195.0
HFD2_k127_4801446_5 THIoesterase K18700 - 3.1.2.29 0.000000000000000000000000001491 116.0
HFD2_k127_4801446_6 Biotin-lipoyl like K01960,K01965,K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.1,6.4.1.3,6.4.1.4 0.00000000000000000000003971 116.0
HFD2_k127_4801446_7 Serine aminopeptidase, S33 K01055 - 3.1.1.24 0.0000000000000004796 90.0
HFD2_k127_4821400_0 CoA-transferase family III K01796 - 5.1.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 503.0
HFD2_k127_4821400_1 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 485.0
HFD2_k127_4821400_10 CoA-transferase family III - - - 0.0000000157 58.0
HFD2_k127_4821400_2 metal-dependent hydrolase of the TIM-barrel fold K07046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 458.0
HFD2_k127_4821400_3 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 351.0
HFD2_k127_4821400_4 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008773 276.0
HFD2_k127_4821400_5 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000001099 231.0
HFD2_k127_4821400_6 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000002704 215.0
HFD2_k127_4821400_7 Redoxin K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000003509 209.0
HFD2_k127_4821400_8 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000009567 150.0
HFD2_k127_4821400_9 cyclic nucleotide binding K10914 - - 0.000000000000000000004673 102.0
HFD2_k127_4872979_0 Dehydrogenase E1 component K21416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007908 351.0
HFD2_k127_4872979_1 PFAM Transketolase K21417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 308.0
HFD2_k127_4872979_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001197 267.0
HFD2_k127_4872979_3 Receptor family ligand binding region family protein 22 K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007025 253.0
HFD2_k127_4872979_4 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000728 260.0
HFD2_k127_4872979_5 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000001032 252.0
HFD2_k127_4872979_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000008688 252.0
HFD2_k127_4872979_7 Domain of unknown function (DUF427) - - - 0.00000000000000000000000000001764 122.0
HFD2_k127_4872979_8 PFAM translation initiation factor SUI1 K03113 - - 0.0000000000000000000000004881 108.0
HFD2_k127_4872979_9 - - - - 0.000000000503 66.0
HFD2_k127_4901662_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 602.0
HFD2_k127_4901662_1 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 385.0
HFD2_k127_4901662_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 302.0
HFD2_k127_4926522_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01577,K01652,K03852 - 2.2.1.6,2.3.3.15,4.1.1.8 7.773e-200 639.0
HFD2_k127_4926522_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 471.0
HFD2_k127_4926522_10 Acetohydroxy acid isomeroreductase, NADPH-binding domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000002071 225.0
HFD2_k127_4926522_11 pfam abc K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000001687 226.0
HFD2_k127_4926522_13 Belongs to the NUDIX hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000004131 121.0
HFD2_k127_4926522_14 PFAM histidine triad (HIT) protein - - - 0.00000000000000000000002192 116.0
HFD2_k127_4926522_15 - - - - 0.000000000000000000000182 109.0
HFD2_k127_4926522_16 protein conserved in bacteria K09984 - - 0.000000000000000004003 87.0
HFD2_k127_4926522_17 rRNA (guanine-N2-)-methyltransferase activity - - - 0.000000000000000006879 91.0
HFD2_k127_4926522_18 TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.000000000000000009947 88.0
HFD2_k127_4926522_19 ABC-2 type transporter K09694 - - 0.00000000000001158 86.0
HFD2_k127_4926522_2 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009457 452.0
HFD2_k127_4926522_20 Endoribonuclease L-PSP - - - 0.0000004251 58.0
HFD2_k127_4926522_3 D-isomer specific 2-hydroxyacid dehydrogenase K00018 - 1.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 430.0
HFD2_k127_4926522_4 PFAM RNA binding S1 domain protein K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 356.0
HFD2_k127_4926522_5 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 306.0
HFD2_k127_4926522_6 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 295.0
HFD2_k127_4926522_7 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005324 265.0
HFD2_k127_4926522_8 TIM-barrel fold metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001866 271.0
HFD2_k127_4926522_9 CYTH - - - 0.0000000000000000000000000000000000000000000000000000000000000000001255 249.0
HFD2_k127_4991062_0 ATPase (P-type) K01535 - 3.6.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 485.0
HFD2_k127_4991062_1 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000003508 198.0
HFD2_k127_4991062_2 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000003918 171.0
HFD2_k127_4991062_3 - - - - 0.00000000000000000000000000000000000000001249 161.0
HFD2_k127_4991062_4 - - - - 0.0000000000000000000000000000000000000008786 151.0
HFD2_k127_4991062_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000001258 96.0
HFD2_k127_5002120_0 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000272 276.0
HFD2_k127_5002120_1 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000000000000000000000000000008601 191.0
HFD2_k127_51362_0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 1.484e-247 778.0
HFD2_k127_51362_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000001531 194.0
HFD2_k127_51362_2 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.00000000000000000006695 91.0
HFD2_k127_5158967_0 Aconitase family (aconitate hydratase) K01681 - 4.2.1.3 7.002e-209 685.0
HFD2_k127_5158967_1 acyl-coa dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009253 574.0
HFD2_k127_5158967_10 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 342.0
HFD2_k127_5158967_11 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 342.0
HFD2_k127_5158967_12 Microcin C7 resistance K01297 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009050,GO:0009056,GO:0009254,GO:0009987,GO:0016787,GO:0019538,GO:0030203,GO:0034641,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 338.0
HFD2_k127_5158967_13 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 320.0
HFD2_k127_5158967_14 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 324.0
HFD2_k127_5158967_15 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 292.0
HFD2_k127_5158967_16 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002992 275.0
HFD2_k127_5158967_17 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007873 276.0
HFD2_k127_5158967_18 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007071 276.0
HFD2_k127_5158967_19 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000001167 229.0
HFD2_k127_5158967_2 dipeptide transport K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 507.0
HFD2_k127_5158967_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000002792 220.0
HFD2_k127_5158967_21 Predicted membrane protein (DUF2339) - - - 0.0000000000000000000000000000000000000000000000001591 201.0
HFD2_k127_5158967_22 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000001765 182.0
HFD2_k127_5158967_23 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.000000000000000000000000000000000000000000000001159 183.0
HFD2_k127_5158967_24 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000002264 176.0
HFD2_k127_5158967_25 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000003022 174.0
HFD2_k127_5158967_26 PFAM FAD dependent oxidoreductase K00301 - 1.5.3.1 0.0000000000000000000000000000000000000000001223 174.0
HFD2_k127_5158967_27 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000006336 158.0
HFD2_k127_5158967_28 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000001511 146.0
HFD2_k127_5158967_29 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000004789 144.0
HFD2_k127_5158967_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K01719,K13542 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,4.1.1.37,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 434.0
HFD2_k127_5158967_30 Protein of unknown function (DUF3752) - - - 0.00000000000000000000000001505 118.0
HFD2_k127_5158967_31 TPM domain - - - 0.000000000000000000002387 107.0
HFD2_k127_5158967_32 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000007879 94.0
HFD2_k127_5158967_33 His Kinase A (phosphoacceptor) domain - - - 0.000000000003754 77.0
HFD2_k127_5158967_34 Carboxymuconolactone decarboxylase family - - - 0.0000004864 61.0
HFD2_k127_5158967_4 protoporphyrinogen oxidase activity K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 428.0
HFD2_k127_5158967_5 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 387.0
HFD2_k127_5158967_6 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 385.0
HFD2_k127_5158967_7 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 386.0
HFD2_k127_5158967_8 PrpF protein K09788 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 372.0
HFD2_k127_5158967_9 Alcohol dehydrogenase GroES-like domain K00001,K00008 - 1.1.1.1,1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 370.0
HFD2_k127_523378_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 8.764e-283 891.0
HFD2_k127_523378_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 3.36e-270 848.0
HFD2_k127_523378_10 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 428.0
HFD2_k127_523378_11 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 437.0
HFD2_k127_523378_12 Proteasomal ATPase OB/ID domain K07184,K07777,K12065,K13525,K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 417.0
HFD2_k127_523378_13 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005856 394.0
HFD2_k127_523378_14 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 383.0
HFD2_k127_523378_15 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 385.0
HFD2_k127_523378_16 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 360.0
HFD2_k127_523378_17 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000711 360.0
HFD2_k127_523378_18 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 351.0
HFD2_k127_523378_19 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 341.0
HFD2_k127_523378_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding K00179 - 1.2.7.8 5.167e-257 809.0
HFD2_k127_523378_20 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K04091 - 1.14.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005617 347.0
HFD2_k127_523378_21 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 340.0
HFD2_k127_523378_22 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 318.0
HFD2_k127_523378_23 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 295.0
HFD2_k127_523378_24 SecD/SecF GG Motif K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008271 274.0
HFD2_k127_523378_25 Creatinase/Prolidase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007527 266.0
HFD2_k127_523378_26 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001716 266.0
HFD2_k127_523378_27 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000002366 239.0
HFD2_k127_523378_28 Belongs to the enoyl-CoA hydratase isomerase family K16880 - - 0.00000000000000000000000000000000000000000000000000000000000000000178 246.0
HFD2_k127_523378_29 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000004263 236.0
HFD2_k127_523378_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.093e-220 705.0
HFD2_k127_523378_30 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000682 219.0
HFD2_k127_523378_31 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000004142 219.0
HFD2_k127_523378_32 PFAM ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000006643 231.0
HFD2_k127_523378_33 PFAM Stage II sporulation K06381 - - 0.00000000000000000000000000000000000000000000000000000007456 222.0
HFD2_k127_523378_34 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000001837 208.0
HFD2_k127_523378_35 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000417 192.0
HFD2_k127_523378_36 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000002639 193.0
HFD2_k127_523378_37 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000006082 178.0
HFD2_k127_523378_38 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000002648 171.0
HFD2_k127_523378_39 Polyketide cyclase / dehydrase and lipid transport K09386 - - 0.0000000000000000000000000000000000000001515 155.0
HFD2_k127_523378_4 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008121 627.0
HFD2_k127_523378_40 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000002569 156.0
HFD2_k127_523378_41 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000444 166.0
HFD2_k127_523378_42 RNA cap guanine-N2 methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000000000001742 148.0
HFD2_k127_523378_43 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000376 137.0
HFD2_k127_523378_44 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000005627 133.0
HFD2_k127_523378_45 Belongs to the enoyl-CoA hydratase isomerase family K01692,K13766 - 4.2.1.17,4.2.1.18 0.0000000000000000000000000000001644 138.0
HFD2_k127_523378_46 protein transport K03210 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000001825 107.0
HFD2_k127_523378_47 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000026 100.0
HFD2_k127_523378_48 Luciferase-like monooxygenase - - - 0.000000000000000000005591 99.0
HFD2_k127_523378_49 Protein of unknown function (DUF2905) - - - 0.00000000000000000001328 93.0
HFD2_k127_523378_5 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007648 524.0
HFD2_k127_523378_50 PFAM Luciferase-like monooxygenase - - - 0.000004166 56.0
HFD2_k127_523378_6 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 529.0
HFD2_k127_523378_7 AMP-binding enzyme C-terminal domain K16876 - 6.2.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 519.0
HFD2_k127_523378_8 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 512.0
HFD2_k127_523378_9 PFAM multi antimicrobial extrusion protein MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 480.0
HFD2_k127_526806_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 473.0
HFD2_k127_526806_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 332.0
HFD2_k127_526806_2 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 319.0
HFD2_k127_526806_3 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 306.0
HFD2_k127_526806_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 309.0
HFD2_k127_526806_5 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002738 278.0
HFD2_k127_526806_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000001179 236.0
HFD2_k127_526806_7 Amidohydrolase - - - 0.000000000000000000000000000000000002282 153.0
HFD2_k127_526806_8 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000005602 105.0
HFD2_k127_5293212_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 386.0
HFD2_k127_5293212_1 branched-chain amino acid K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 312.0
HFD2_k127_5293212_2 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000003539 232.0
HFD2_k127_5297483_0 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs - - - 1.018e-246 786.0
HFD2_k127_5297483_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 373.0
HFD2_k127_5297483_10 Cupin domain - - - 0.00000000000000000000000000005574 121.0
HFD2_k127_5297483_11 dTDP biosynthetic process K00560,K00943 - 2.1.1.45,2.7.4.9 0.0001356 48.0
HFD2_k127_5297483_2 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 346.0
HFD2_k127_5297483_3 PFAM Branched-chain amino acid transport system permease component K01997,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005932 276.0
HFD2_k127_5297483_4 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000007802 252.0
HFD2_k127_5297483_5 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000001274 240.0
HFD2_k127_5297483_6 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS - - - 0.0000000000000000000000000000000000000000000000000000006428 200.0
HFD2_k127_5297483_7 HpcH HpaI aldolase K01630,K02510 - 4.1.2.20,4.1.2.52 0.0000000000000000000000000000000000000000005835 167.0
HFD2_k127_5297483_8 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000429 157.0
HFD2_k127_5297483_9 cheY-homologous receiver domain - - - 0.000000000000000000000000000003703 124.0
HFD2_k127_5305913_0 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009221 349.0
HFD2_k127_5305913_1 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000003876 236.0
HFD2_k127_5305913_2 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000001045 114.0
HFD2_k127_5309841_0 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006011 415.0
HFD2_k127_5309841_1 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000007966 230.0
HFD2_k127_5309841_3 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000003859 194.0
HFD2_k127_5309841_4 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000003974 180.0
HFD2_k127_5309841_5 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K03325,K03741,K03892,K18701 - 1.20.4.1,2.8.4.2,3.1.3.48 0.000000000000000000001682 110.0
HFD2_k127_5315011_0 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.0000000000000000000000000000000000000003194 162.0
HFD2_k127_5315011_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 0.00000000000000000002643 96.0
HFD2_k127_5315011_2 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.0001145 48.0
HFD2_k127_5322631_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 8.052e-211 662.0
HFD2_k127_5322631_1 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 591.0
HFD2_k127_5322631_10 diguanylate cyclase - - - 0.00000000000000000000000000000000000006249 159.0
HFD2_k127_5322631_11 PFAM transport-associated - - - 0.000000000000000000000000000001621 133.0
HFD2_k127_5322631_12 Arabinose efflux permease family protein - - - 0.000000000000000000000001339 118.0
HFD2_k127_5322631_13 response regulator - - - 0.0000000000000000000000196 104.0
HFD2_k127_5322631_14 ATP-binding region, ATPase domain protein - - - 0.0000000000000000000001099 106.0
HFD2_k127_5322631_15 regulatory protein, FmdB family - - - 0.000000008289 62.0
HFD2_k127_5322631_16 Prokaryotic N-terminal methylation motif K02650 - - 0.00000001223 65.0
HFD2_k127_5322631_18 Cytochrome C' - - - 0.00003679 52.0
HFD2_k127_5322631_19 Periplasmic binding protein domain K10439 - - 0.0002485 53.0
HFD2_k127_5322631_2 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 430.0
HFD2_k127_5322631_3 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K04772 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 355.0
HFD2_k127_5322631_4 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 321.0
HFD2_k127_5322631_5 Caspase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003111 264.0
HFD2_k127_5322631_6 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000001064 227.0
HFD2_k127_5322631_7 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000001347 203.0
HFD2_k127_5322631_8 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000001082 184.0
HFD2_k127_5322631_9 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000194 171.0
HFD2_k127_5334507_0 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.00000000000000000000000000000000000000000000003837 180.0
HFD2_k127_5334507_1 Peptide-binding protein - - - 0.00000000001313 76.0
HFD2_k127_5347516_0 COG2303 Choline dehydrogenase and related flavoproteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 423.0
HFD2_k127_5347516_1 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 401.0
HFD2_k127_5347516_10 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000005769 267.0
HFD2_k127_5347516_11 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000003525 235.0
HFD2_k127_5347516_12 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000008439 220.0
HFD2_k127_5347516_13 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000002264 220.0
HFD2_k127_5347516_14 PFAM NADP oxidoreductase coenzyme F420-dependent K00020 - 1.1.1.31 0.0000000000000000000000000000000000007937 158.0
HFD2_k127_5347516_15 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000001169 127.0
HFD2_k127_5347516_16 COG0457 FOG TPR repeat - - - 0.00000000000000000000000003761 124.0
HFD2_k127_5347516_17 Rieske [2Fe-2S] domain K15762 - - 0.0000000000000000000000326 108.0
HFD2_k127_5347516_18 Ferredoxin - - - 0.0000000000000000001349 97.0
HFD2_k127_5347516_19 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000329 70.0
HFD2_k127_5347516_2 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 386.0
HFD2_k127_5347516_3 Oxidoreductase FAD-binding domain K15765 - 1.18.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006468 364.0
HFD2_k127_5347516_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 378.0
HFD2_k127_5347516_5 cysteine-tRNA ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 351.0
HFD2_k127_5347516_6 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 331.0
HFD2_k127_5347516_7 Amino-transferase class IV K18482 - 4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 301.0
HFD2_k127_5347516_8 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000714 289.0
HFD2_k127_5347516_9 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000009782 267.0
HFD2_k127_5353473_0 MgtE intracellular N domain K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 564.0
HFD2_k127_5353473_1 3-isopropylmalate dehydrogenase activity K00052,K05824 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0047046,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85,1.1.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001102 286.0
HFD2_k127_5353473_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000233 216.0
HFD2_k127_5353473_3 Protein of unknown function (DUF3830) - - - 0.000000000000000000000000000000000000000000000000000007058 212.0
HFD2_k127_5353473_4 - - - - 0.0000000000000000000000000000000000000000000000000001854 209.0
HFD2_k127_5353473_5 P-aminobenzoate N-oxygenase AurF - - - 0.00000000000000000000000000000000000000000000692 177.0
HFD2_k127_5353473_6 COG0471 Di- and tricarboxylate transporters K14445 - - 0.0000000000000000000000000000004572 139.0
HFD2_k127_5353473_7 IMP dehydrogenase activity - - - 0.00000000000000000000001716 111.0
HFD2_k127_5353473_8 thiolester hydrolase activity K02614 - - 0.000000001453 63.0
HFD2_k127_5353473_9 Thioesterase superfamily - - - 0.00004319 48.0
HFD2_k127_5383963_0 asparagine K01953 - 6.3.5.4 3.032e-272 850.0
HFD2_k127_5383963_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 9.989e-266 844.0
HFD2_k127_5383963_2 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 466.0
HFD2_k127_5383963_3 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000003361 83.0
HFD2_k127_5384366_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 1340.0
HFD2_k127_5384366_1 PFAM ABC transporter K02471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 625.0
HFD2_k127_5384366_2 PFAM ABC transporter, transmembrane region K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 405.0
HFD2_k127_5384366_3 Transposase domain (DUF772) K07487 - - 0.000000000000000000000000000000000000000000000000000000000002898 220.0
HFD2_k127_5384366_4 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0000000000000000000000000000002716 132.0
HFD2_k127_5384366_5 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.000000000000000000000000003575 122.0
HFD2_k127_5384366_6 Integrin alpha (beta-propellor repeats). - - - 0.0000000000000000001035 100.0
HFD2_k127_5384366_7 translation initiation factor activity K06996 - - 0.000000000004225 72.0
HFD2_k127_5400840_0 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 597.0
HFD2_k127_5400840_1 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 502.0
HFD2_k127_5400840_2 Transposase domain (DUF772) K07487 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009815 457.0
HFD2_k127_5400840_3 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 445.0
HFD2_k127_5400840_4 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000006833 270.0
HFD2_k127_5400840_5 acetyltransferases and hydrolases with the alpha beta hydrolase fold K00650 - 2.3.1.43 0.00000000000000000000000000000000000000000000000000000000000000000000001076 255.0
HFD2_k127_5400840_6 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000002804 228.0
HFD2_k127_5405441_0 Luciferase-like monooxygenase - - - 2.399e-207 649.0
HFD2_k127_5405441_1 PFAM 4-hydroxyphenylacetate 3-hydroxylase K00483,K16901 - 1.14.14.8,1.14.14.9 1.858e-202 643.0
HFD2_k127_5405441_10 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001287 301.0
HFD2_k127_5405441_11 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004546 291.0
HFD2_k127_5405441_12 oxidation-reduction process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005599 248.0
HFD2_k127_5405441_13 glycolate biosynthetic process K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000006287 239.0
HFD2_k127_5405441_14 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000502 228.0
HFD2_k127_5405441_15 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000001056 219.0
HFD2_k127_5405441_16 MarR family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000002126 173.0
HFD2_k127_5405441_17 Cupin domain - - - 0.00000000000000000000000000000000000000001215 169.0
HFD2_k127_5405441_18 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000001545 168.0
HFD2_k127_5405441_19 Proteasomal ATPase OB/ID domain K13527 - - 0.0000000000000000000000000000000000000003317 151.0
HFD2_k127_5405441_2 Pup-ligase protein K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 597.0
HFD2_k127_5405441_20 DinB superfamily - - - 0.00000000000000002487 88.0
HFD2_k127_5405441_21 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.00000000000003564 78.0
HFD2_k127_5405441_22 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000008289 62.0
HFD2_k127_5405441_3 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 581.0
HFD2_k127_5405441_4 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 444.0
HFD2_k127_5405441_5 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 392.0
HFD2_k127_5405441_6 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 353.0
HFD2_k127_5405441_7 alcohol dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 345.0
HFD2_k127_5405441_8 Proteasome subunit K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 310.0
HFD2_k127_5405441_9 Proteasome subunit K03432 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 289.0
HFD2_k127_5410811_0 N-methylhydantoinase B acetone carboxylase alpha subunit - - - 5.75e-206 657.0
HFD2_k127_5410811_1 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 627.0
HFD2_k127_5410811_2 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 428.0
HFD2_k127_5410811_3 transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004302 294.0
HFD2_k127_5410811_4 Transcriptional regulatory protein, C terminal K07776 - - 0.0000000000000000000005898 104.0
HFD2_k127_5410811_5 Hydantoinase/oxoprolinase K01473 - 3.5.2.14 0.000000000000000000008062 96.0
HFD2_k127_5422512_0 Glycine cleavage system P-protein K00283 - 1.4.4.2 7.455e-196 629.0
HFD2_k127_5422512_1 PFAM Mandelate racemase muconate lactonizing K20023 - 4.2.1.156,4.2.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 537.0
HFD2_k127_5422512_10 Threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 380.0
HFD2_k127_5422512_11 ABC-type uncharacterized transport system K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009988 360.0
HFD2_k127_5422512_12 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 347.0
HFD2_k127_5422512_13 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007779 283.0
HFD2_k127_5422512_14 Allophanate hydrolase subunit 2 K06350 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003249 273.0
HFD2_k127_5422512_15 DNA polymerase alpha chain like domain K07053,K20859 - 3.1.3.97,3.1.4.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000008507 266.0
HFD2_k127_5422512_16 Metallo-beta-lactamase superfamily K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000001634 264.0
HFD2_k127_5422512_17 Domain of unknown function (DUF4340) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004505 259.0
HFD2_k127_5422512_18 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000004372 264.0
HFD2_k127_5422512_19 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.000000000000000000000000000000000000000000000004668 178.0
HFD2_k127_5422512_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 495.0
HFD2_k127_5422512_20 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000001809 176.0
HFD2_k127_5422512_21 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.0000000000000000000000000000000000000008183 163.0
HFD2_k127_5422512_22 major facilitator superfamily - - - 0.000000000000000000000000000000000000002188 163.0
HFD2_k127_5422512_23 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000474 141.0
HFD2_k127_5422512_24 NUDIX domain - - - 0.00000000000000000000000000000351 135.0
HFD2_k127_5422512_25 Molybdopterin oxidoreductase Fe4S4 domain K00380,K02567 - 1.8.1.2 0.0000000000000000000000000000347 132.0
HFD2_k127_5422512_26 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000009765 117.0
HFD2_k127_5422512_27 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000447 107.0
HFD2_k127_5422512_28 COG0715 ABC-type nitrate sulfonate K15576,K22067 - - 0.00000000000001745 81.0
HFD2_k127_5422512_29 Thioesterase superfamily - - - 0.0001998 55.0
HFD2_k127_5422512_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 481.0
HFD2_k127_5422512_4 COG0444 ABC-type dipeptide oligopeptide nickel transport system, ATPase component K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 455.0
HFD2_k127_5422512_5 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 400.0
HFD2_k127_5422512_6 conserved protein (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 386.0
HFD2_k127_5422512_7 Sugar (and other) transporter K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 395.0
HFD2_k127_5422512_8 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 381.0
HFD2_k127_5422512_9 Belongs to the D-glutamate cyclase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008443 364.0
HFD2_k127_5438723_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1033.0
HFD2_k127_5438723_1 FAD linked oxidases, C-terminal domain - - - 5.337e-308 970.0
HFD2_k127_5438723_10 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 538.0
HFD2_k127_5438723_11 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 510.0
HFD2_k127_5438723_12 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005757 512.0
HFD2_k127_5438723_13 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K19837 - 3.5.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 499.0
HFD2_k127_5438723_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 510.0
HFD2_k127_5438723_15 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007764 515.0
HFD2_k127_5438723_16 formamidase K01455 - 3.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006441 459.0
HFD2_k127_5438723_17 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 473.0
HFD2_k127_5438723_18 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 469.0
HFD2_k127_5438723_19 alpha beta alpha domain I K01840,K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 445.0
HFD2_k127_5438723_2 Adenylate and Guanylate cyclase catalytic domain - - - 2.544e-290 948.0
HFD2_k127_5438723_20 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 432.0
HFD2_k127_5438723_21 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 421.0
HFD2_k127_5438723_22 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 381.0
HFD2_k127_5438723_23 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 376.0
HFD2_k127_5438723_24 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 364.0
HFD2_k127_5438723_25 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714,K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 378.0
HFD2_k127_5438723_26 COG0665 Glycine D-amino acid oxidases (deaminating) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 345.0
HFD2_k127_5438723_27 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 338.0
HFD2_k127_5438723_28 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006685 359.0
HFD2_k127_5438723_29 NAD(P)-binding Rossmann-like domain K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 340.0
HFD2_k127_5438723_3 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain K01596,K01610 - 4.1.1.32,4.1.1.49 2.082e-258 807.0
HFD2_k127_5438723_30 acyl-CoA transferases carnitine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 338.0
HFD2_k127_5438723_31 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 348.0
HFD2_k127_5438723_32 PFAM Copper resistance D K07245 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 338.0
HFD2_k127_5438723_33 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009167 318.0
HFD2_k127_5438723_34 cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007665 301.0
HFD2_k127_5438723_35 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 319.0
HFD2_k127_5438723_36 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 315.0
HFD2_k127_5438723_37 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 298.0
HFD2_k127_5438723_38 Universal stress protein UspA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 289.0
HFD2_k127_5438723_39 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006331 282.0
HFD2_k127_5438723_4 helicase superfamily c-terminal domain K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 6.186e-231 742.0
HFD2_k127_5438723_40 Belongs to the bacterial solute-binding protein 9 family K09815,K09818 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005089 284.0
HFD2_k127_5438723_41 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004733 296.0
HFD2_k127_5438723_42 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000004475 276.0
HFD2_k127_5438723_43 ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001333 268.0
HFD2_k127_5438723_44 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000132 255.0
HFD2_k127_5438723_45 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000002225 263.0
HFD2_k127_5438723_46 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000003502 245.0
HFD2_k127_5438723_47 NAD binding K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000001187 259.0
HFD2_k127_5438723_48 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000001393 250.0
HFD2_k127_5438723_49 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000005156 250.0
HFD2_k127_5438723_5 AMP-binding enzyme K01897 - 6.2.1.3 8.996e-221 714.0
HFD2_k127_5438723_50 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000001662 234.0
HFD2_k127_5438723_51 Inositol monophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000001688 233.0
HFD2_k127_5438723_52 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781 - 5.1.2.2 0.00000000000000000000000000000000000000000000000000000000000003033 242.0
HFD2_k127_5438723_53 Belongs to the BI1 family K06890 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000004919 221.0
HFD2_k127_5438723_54 ABC-type Mn2 Zn2 transport K09816 - - 0.00000000000000000000000000000000000000000000000000000000003577 214.0
HFD2_k127_5438723_55 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000005857 223.0
HFD2_k127_5438723_56 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000001528 214.0
HFD2_k127_5438723_57 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.0000000000000000000000000000000000000000000000000000000001919 211.0
HFD2_k127_5438723_58 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000003297 212.0
HFD2_k127_5438723_59 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000002396 208.0
HFD2_k127_5438723_6 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 3.043e-214 673.0
HFD2_k127_5438723_60 acetylesterase activity K01046 - 3.1.1.3 0.00000000000000000000000000000000000000000000000000000002659 222.0
HFD2_k127_5438723_61 Serine hydrolase K07002 - - 0.0000000000000000000000000000000000000000000000000000003081 202.0
HFD2_k127_5438723_62 thiamine-containing compound biosynthetic process K02051,K15553 - - 0.0000000000000000000000000000000000000000000000000000006514 205.0
HFD2_k127_5438723_63 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000006057 190.0
HFD2_k127_5438723_64 PFAM YdjC family protein K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000002005 186.0
HFD2_k127_5438723_65 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.000000000000000000000000000000000000000000000002112 198.0
HFD2_k127_5438723_66 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000007986 181.0
HFD2_k127_5438723_67 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon K03709 - - 0.000000000000000000000000000000000000000000009914 186.0
HFD2_k127_5438723_68 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000004896 168.0
HFD2_k127_5438723_69 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.00000000000000000000000000000000000000002996 161.0
HFD2_k127_5438723_7 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009279 612.0
HFD2_k127_5438723_70 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000000000002263 166.0
HFD2_k127_5438723_71 Lipid A Biosynthesis N-terminal domain - - - 0.00000000000000000000000000000000001252 138.0
HFD2_k127_5438723_72 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000000001165 134.0
HFD2_k127_5438723_73 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.0000000000000000000005569 99.0
HFD2_k127_5438723_74 Thioredoxin-like - - - 0.0000000000000000004868 94.0
HFD2_k127_5438723_75 Domain of Unknown Function (DUF748) - - - 0.0000000000000002567 95.0
HFD2_k127_5438723_76 Phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.0000000000001942 80.0
HFD2_k127_5438723_78 acr, cog1430 K09005 - - 0.000000001946 70.0
HFD2_k127_5438723_79 - - - - 0.000000004289 63.0
HFD2_k127_5438723_8 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 602.0
HFD2_k127_5438723_81 Mo-molybdopterin cofactor metabolic process - - - 0.00003698 56.0
HFD2_k127_5438723_82 alcohol dehydrogenase - - - 0.0001643 51.0
HFD2_k127_5438723_9 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 545.0
HFD2_k127_5441841_0 DEAD/H associated K03724 - - 0.0 1384.0
HFD2_k127_5441841_1 6-phosphofructokinase activity K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 569.0
HFD2_k127_5441841_2 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 407.0
HFD2_k127_5441841_3 Membrane protein, TerC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001715 274.0
HFD2_k127_5441841_4 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003525 270.0
HFD2_k127_5441841_5 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000193 267.0
HFD2_k127_5441841_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000002488 205.0
HFD2_k127_5441841_7 YbaK prolyl-tRNA synthetase associated region - - - 0.000000000000000000000000000000000000001745 153.0
HFD2_k127_5441841_9 - - - - 0.00000000001078 66.0
HFD2_k127_547745_0 PFAM Sodium sulphate symporter K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 416.0
HFD2_k127_547745_1 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.00000000000000000000000000000000000000000005915 180.0
HFD2_k127_547745_2 Domain of unknown function (DUF4437) - - - 0.000000000000000000000008872 107.0
HFD2_k127_5479348_0 sigma-54 factor interaction domain-containing protein K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 398.0
HFD2_k127_5479348_1 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 305.0
HFD2_k127_5479348_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005904 256.0
HFD2_k127_5479348_3 cheY-homologous receiver domain - - - 0.0000000000000000002906 101.0
HFD2_k127_5479348_4 Protein of unknown function (DUF1634) - - - 0.0009979 51.0
HFD2_k127_5490135_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.0 1044.0
HFD2_k127_5490135_1 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 623.0
HFD2_k127_5490135_10 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006457 389.0
HFD2_k127_5490135_11 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 370.0
HFD2_k127_5490135_12 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 342.0
HFD2_k127_5490135_13 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 335.0
HFD2_k127_5490135_14 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 319.0
HFD2_k127_5490135_15 Family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 316.0
HFD2_k127_5490135_16 BFD-like [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 305.0
HFD2_k127_5490135_17 PFAM FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005625 286.0
HFD2_k127_5490135_18 ABC transporter permease K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001347 289.0
HFD2_k127_5490135_19 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002924 299.0
HFD2_k127_5490135_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 584.0
HFD2_k127_5490135_20 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005501 284.0
HFD2_k127_5490135_21 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000004948 260.0
HFD2_k127_5490135_22 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005982 269.0
HFD2_k127_5490135_23 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000439 241.0
HFD2_k127_5490135_24 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005199 234.0
HFD2_k127_5490135_25 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000003026 196.0
HFD2_k127_5490135_26 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000009933 177.0
HFD2_k127_5490135_27 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000001854 156.0
HFD2_k127_5490135_28 DinB superfamily - - - 0.0000000000000000000000000000000000000002593 158.0
HFD2_k127_5490135_29 Glyoxalase-like domain K08234 - - 0.0000000000000000000000000000000000000003898 154.0
HFD2_k127_5490135_3 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 489.0
HFD2_k127_5490135_30 Haem-degrading - - - 0.000000000000000000000000000000000000006371 154.0
HFD2_k127_5490135_31 Protein of unknown function DUF86 - - - 0.000000000000000000000000000000000002597 147.0
HFD2_k127_5490135_32 Tyrosine phosphatase family - - - 0.00000000000000000000000000004442 122.0
HFD2_k127_5490135_33 Nucleotidyltransferase domain - - - 0.0000000000000000000000000002817 119.0
HFD2_k127_5490135_34 Protein of unknown function (DUF3024) - - - 0.00000000000000000000002095 104.0
HFD2_k127_5490135_35 Methyltransferase domain - - - 0.0000000000000000002229 96.0
HFD2_k127_5490135_36 -acetyltransferase - - - 0.0000000000000000542 89.0
HFD2_k127_5490135_37 N-acyl-D-aspartate D-glutamate deacylase K01465,K06015 - 3.5.1.81,3.5.2.3 0.000000000006152 76.0
HFD2_k127_5490135_38 Belongs to the 'phage' integrase family K14059 - - 0.0000000007601 66.0
HFD2_k127_5490135_39 amine dehydrogenase activity K01751,K01754 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008838,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575 4.3.1.15,4.3.1.19 0.0007146 53.0
HFD2_k127_5490135_4 Xaa-Pro aminopeptidase K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 446.0
HFD2_k127_5490135_5 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K14471,K14472 - 2.8.3.16,2.8.3.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 412.0
HFD2_k127_5490135_6 COG0747 ABC-type dipeptide transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005685 429.0
HFD2_k127_5490135_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 404.0
HFD2_k127_5490135_8 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008339 385.0
HFD2_k127_5490135_9 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000837 379.0
HFD2_k127_5493442_0 Periplasmic binding protein domain K01999 - - 4.131e-231 722.0
HFD2_k127_5493442_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008439 566.0
HFD2_k127_5493442_10 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000623 290.0
HFD2_k127_5493442_11 Alpha beta hydrolase - - - 0.00000000000009201 86.0
HFD2_k127_5493442_12 amidohydrolase K07045 - - 0.00000028 59.0
HFD2_k127_5493442_2 AAA ATPase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007722 531.0
HFD2_k127_5493442_3 AAA ATPase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 535.0
HFD2_k127_5493442_4 AAA ATPase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 497.0
HFD2_k127_5493442_5 alpha-L-arabinofuranosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 498.0
HFD2_k127_5493442_6 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007527 431.0
HFD2_k127_5493442_7 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 414.0
HFD2_k127_5493442_8 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 375.0
HFD2_k127_5493442_9 ATPases associated with a variety of cellular activities K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 314.0
HFD2_k127_5515874_0 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 502.0
HFD2_k127_5515874_1 heme binding - - - 0.000000000000000000000000000000000000000000000000009895 190.0
HFD2_k127_5549138_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.995e-202 638.0
HFD2_k127_5549138_1 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006051 472.0
HFD2_k127_5549138_2 Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 334.0
HFD2_k127_5549138_3 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000007893 211.0
HFD2_k127_5549138_4 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000000001098 154.0
HFD2_k127_5549138_5 3-hydroxyanthranilic acid dioxygenase K00452 - 1.13.11.6 0.000000000000000000000000000000000000003725 149.0
HFD2_k127_5549138_6 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.000001445 51.0
HFD2_k127_5549138_7 PFAM Protein kinase domain K08884 - 2.7.11.1 0.000002938 58.0
HFD2_k127_5549138_8 ATPases associated with a variety of cellular activities K01996 - - 0.0002708 49.0
HFD2_k127_5577933_0 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 499.0
HFD2_k127_5577933_1 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001444 274.0
HFD2_k127_5577933_2 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000008863 126.0
HFD2_k127_5588216_0 Hydantoinaseoxoprolinase domain protein K01469,K01473 - 3.5.2.14,3.5.2.9 1.959e-252 797.0
HFD2_k127_5588216_1 General secretory system II protein E domain protein K02652 - - 1.981e-194 627.0
HFD2_k127_5588216_10 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 316.0
HFD2_k127_5588216_11 ABC transporter, ATP-binding protein K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 299.0
HFD2_k127_5588216_12 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 304.0
HFD2_k127_5588216_13 GTP binding K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001791 252.0
HFD2_k127_5588216_14 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000006966 246.0
HFD2_k127_5588216_15 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000131 251.0
HFD2_k127_5588216_16 Iron-containing redox enzyme K06137 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000000000000000000004873 242.0
HFD2_k127_5588216_17 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000008799 232.0
HFD2_k127_5588216_18 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000001066 226.0
HFD2_k127_5588216_19 type IV pilus secretin PilQ K02666 - - 0.000000000000000000000000000000000000000000000000001959 207.0
HFD2_k127_5588216_2 PFAM Hydantoinase B oxoprolinase K01469,K01474 - 3.5.2.14,3.5.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 622.0
HFD2_k127_5588216_20 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000002147 180.0
HFD2_k127_5588216_21 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000847 163.0
HFD2_k127_5588216_22 Thioredoxin-like domain K03671 - - 0.0000000000000000000000000000000001188 136.0
HFD2_k127_5588216_23 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000001093 137.0
HFD2_k127_5588216_24 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000253 134.0
HFD2_k127_5588216_25 cheY-homologous receiver domain - - - 0.000000000000000000000000002695 123.0
HFD2_k127_5588216_26 Roadblock/LC7 domain - - - 0.0000000000000000000000014 117.0
HFD2_k127_5588216_27 (Rieske (2Fe-2S) domain) K00363,K05710 - 1.7.1.15 0.00000000000000000000001961 103.0
HFD2_k127_5588216_28 Anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000001591 96.0
HFD2_k127_5588216_29 Tetratricopeptide repeat K00661,K18626 - 2.3.1.79 0.0000000000000004461 87.0
HFD2_k127_5588216_3 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 554.0
HFD2_k127_5588216_30 COG3167 Tfp pilus assembly protein PilO K02664 - - 0.00000000000000684 83.0
HFD2_k127_5588216_31 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000219 77.0
HFD2_k127_5588216_32 Haem-degrading - - - 0.000000000006586 75.0
HFD2_k127_5588216_33 Tetratricopeptide repeat - - - 0.0000002235 62.0
HFD2_k127_5588216_34 type IV pilus modification protein PilV K02671,K02681,K10927 - - 0.000003338 58.0
HFD2_k127_5588216_35 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00003382 55.0
HFD2_k127_5588216_36 Pilus assembly protein, PilP K02665 - - 0.0002695 52.0
HFD2_k127_5588216_4 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 521.0
HFD2_k127_5588216_5 branched-chain amino acid transport system, permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 451.0
HFD2_k127_5588216_6 arsenite transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 430.0
HFD2_k127_5588216_7 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 423.0
HFD2_k127_5588216_8 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 360.0
HFD2_k127_5588216_9 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000097 339.0
HFD2_k127_5615492_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000003853 222.0
HFD2_k127_5615492_1 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000009032 153.0
HFD2_k127_5615492_2 - - - - 0.000000006498 63.0
HFD2_k127_5615492_3 monooxygenase activity K16242 - - 0.00000002455 65.0
HFD2_k127_565620_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 4.723e-284 882.0
HFD2_k127_565620_1 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 497.0
HFD2_k127_565620_10 PFAM 2-nitropropane dioxygenase NPD K02371 - 1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000003915 267.0
HFD2_k127_565620_11 Enoyl-(Acyl carrier protein) reductase K00059,K10780 - 1.1.1.100,1.3.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000001453 247.0
HFD2_k127_565620_12 SelR domain K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000007131 227.0
HFD2_k127_565620_13 Alpha beta hydrolase - - - 0.00000000000000000000000000000002688 144.0
HFD2_k127_565620_14 Major Facilitator Superfamily - - - 0.0000000000000000000001728 102.0
HFD2_k127_565620_15 - - - - 0.0000000000000184 76.0
HFD2_k127_565620_17 Major Facilitator Superfamily - - - 0.00009115 53.0
HFD2_k127_565620_2 III protein, CoA-transferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 488.0
HFD2_k127_565620_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 463.0
HFD2_k127_565620_4 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007496 459.0
HFD2_k127_565620_5 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 363.0
HFD2_k127_565620_6 Isochorismatase family K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009447 332.0
HFD2_k127_565620_7 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 326.0
HFD2_k127_565620_8 Putative FMN-binding domain K07734 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002891 273.0
HFD2_k127_565620_9 wide pore channel activity K07267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003223 281.0
HFD2_k127_5659490_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K04105,K04110 - 6.2.1.25,6.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 557.0
HFD2_k127_5659490_1 NMT1 THI5-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006949 325.0
HFD2_k127_5659490_2 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 300.0
HFD2_k127_5659490_3 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000008501 265.0
HFD2_k127_5659841_0 4-hydroxyphenylacetate 3-hydroxylase C terminal - - - 8.241e-238 751.0
HFD2_k127_5659841_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.437e-236 749.0
HFD2_k127_5659841_10 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000434 275.0
HFD2_k127_5659841_11 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006311 257.0
HFD2_k127_5659841_12 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000002857 249.0
HFD2_k127_5659841_13 Protein of unknown function DUF47 K02039,K07220 - - 0.00000000000000000000000000000000000000000000000000000000000003604 221.0
HFD2_k127_5659841_14 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000003427 211.0
HFD2_k127_5659841_15 PFAM peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000475 185.0
HFD2_k127_5659841_16 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000005342 200.0
HFD2_k127_5659841_17 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000221 175.0
HFD2_k127_5659841_18 short-chain dehydrogenase K07535,K10620 - 1.3.1.58 0.0000000000000000000000000000000000000000000002382 182.0
HFD2_k127_5659841_19 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000003966 173.0
HFD2_k127_5659841_2 Molydopterin dinucleotide binding domain K07306,K07309,K07310,K08352 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009390,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0033797,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.8.5.3,1.8.5.5,1.97.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 569.0
HFD2_k127_5659841_20 SnoaL-like domain - - - 0.000000000000000000000000000000000000001424 153.0
HFD2_k127_5659841_21 Creatinase/Prolidase N-terminal domain - - - 0.0000000000000000000000000000000000003473 156.0
HFD2_k127_5659841_22 Domain of unknown function (DUF1772) - - - 0.00000000000000000000000000000000002607 153.0
HFD2_k127_5659841_23 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.00000000000000000000000002675 119.0
HFD2_k127_5659841_24 Major Facilitator Superfamily - - - 0.0000000000000000000000007246 118.0
HFD2_k127_5659841_25 antibiotic biosynthesis - - - 0.0000000000000000000001018 110.0
HFD2_k127_5659841_26 Mo-molybdopterin cofactor metabolic process - - - 0.000000000000000003513 86.0
HFD2_k127_5659841_27 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000007201 79.0
HFD2_k127_5659841_28 Protein of unknown function (DUF861) - - - 0.00000000000005273 79.0
HFD2_k127_5659841_29 - - - - 0.0000000001154 64.0
HFD2_k127_5659841_3 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 544.0
HFD2_k127_5659841_4 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 465.0
HFD2_k127_5659841_5 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 424.0
HFD2_k127_5659841_6 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 414.0
HFD2_k127_5659841_7 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 388.0
HFD2_k127_5659841_8 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 381.0
HFD2_k127_5659841_9 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000584 287.0
HFD2_k127_5660517_0 Histidine kinase-like ATPases - - - 0.0 1096.0
HFD2_k127_5660517_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576,K01652 - 2.2.1.6,4.1.1.7 2.041e-214 681.0
HFD2_k127_5660517_10 Aldo/keto reductase family K18471 - - 0.0000000000000000000000000000000000000000000000000000000000000000004706 242.0
HFD2_k127_5660517_11 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000001956 218.0
HFD2_k127_5660517_12 PFAM Deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000006762 183.0
HFD2_k127_5660517_13 Luciferase-like monooxygenase - - - 0.000000000000000000336 91.0
HFD2_k127_5660517_14 alpha, beta - - - 0.0000000004084 66.0
HFD2_k127_5660517_2 Belongs to the ABC transporter superfamily K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 475.0
HFD2_k127_5660517_3 Taurine catabolism dioxygenase TauD, TfdA family K06912 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 463.0
HFD2_k127_5660517_4 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 429.0
HFD2_k127_5660517_5 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 387.0
HFD2_k127_5660517_6 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 365.0
HFD2_k127_5660517_7 F420-dependent oxidoreductase, MSMEG_3544 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 300.0
HFD2_k127_5660517_8 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002236 278.0
HFD2_k127_5660517_9 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007928 265.0
HFD2_k127_5662380_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 2.902e-220 695.0
HFD2_k127_5662380_1 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 559.0
HFD2_k127_5662380_10 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 308.0
HFD2_k127_5662380_11 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 302.0
HFD2_k127_5662380_12 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002363 248.0
HFD2_k127_5662380_13 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000004588 255.0
HFD2_k127_5662380_14 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000002735 210.0
HFD2_k127_5662380_15 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000007572 201.0
HFD2_k127_5662380_16 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000003432 192.0
HFD2_k127_5662380_17 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000009907 186.0
HFD2_k127_5662380_18 MlaD protein K06192 - - 0.0000000000000000000000000000000000000004033 169.0
HFD2_k127_5662380_19 Protein of unknown function, DUF - - - 0.00000000000000000000000000000000000001053 149.0
HFD2_k127_5662380_2 PFAM amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 543.0
HFD2_k127_5662380_20 ABC-type transport auxiliary lipoprotein component K09857 - - 0.00000000000000000000000000000000001878 154.0
HFD2_k127_5662380_22 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 GO:0000287,GO:0003674,GO:0003824,GO:0004016,GO:0004383,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006182,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0007186,GO:0007187,GO:0007188,GO:0007189,GO:0008074,GO:0008150,GO:0008152,GO:0008179,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0010033,GO:0014070,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019899,GO:0019932,GO:0019933,GO:0019935,GO:0023052,GO:0030145,GO:0030425,GO:0031224,GO:0031226,GO:0031683,GO:0032991,GO:0033993,GO:0034641,GO:0034654,GO:0035556,GO:0035690,GO:0036477,GO:0042221,GO:0042493,GO:0042995,GO:0043005,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044444,GO:0044445,GO:0044459,GO:0044463,GO:0044464,GO:0044877,GO:0045121,GO:0046058,GO:0046068,GO:0046390,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0046982,GO:0046983,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052652,GO:0055086,GO:0061478,GO:0065007,GO:0070887,GO:0071236,GO:0071310,GO:0071396,GO:0071407,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097305,GO:0097306,GO:0097447,GO:0097458,GO:0098589,GO:0098805,GO:0098857,GO:0120025,GO:0120038,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901654,GO:1901655,GO:1901700,GO:1901701,GO:1904321,GO:1904322 4.6.1.1 0.0000000000002506 82.0
HFD2_k127_5662380_23 - - - - 0.000000000000382 77.0
HFD2_k127_5662380_24 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000007697 63.0
HFD2_k127_5662380_25 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.000001989 54.0
HFD2_k127_5662380_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 435.0
HFD2_k127_5662380_4 Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 426.0
HFD2_k127_5662380_5 phosphoglycerate mutase activity K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 403.0
HFD2_k127_5662380_6 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 398.0
HFD2_k127_5662380_7 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008663 415.0
HFD2_k127_5662380_8 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 373.0
HFD2_k127_5662380_9 Thiamine pyrophosphate protein TPP binding domain protein K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 364.0
HFD2_k127_5717100_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 3.361e-214 681.0
HFD2_k127_5717100_1 ATPase associated with various cellular K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009503 356.0
HFD2_k127_5717100_2 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007739 264.0
HFD2_k127_5717100_3 Domain of unknown function (DUF3488) - - - 0.000000000000000000000000000000000000000000000000000000000000001876 243.0
HFD2_k127_5717100_4 cob(I)yrinic acid a,c-diamide adenosyltransferase activity K00798,K13821 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.2.1.88,1.5.5.2,2.5.1.17 0.00000000000000000000000000000000000000000000000000000000001749 212.0
HFD2_k127_5717100_5 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000000000001964 191.0
HFD2_k127_5717100_6 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000991 180.0
HFD2_k127_5717100_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000005414 95.0
HFD2_k127_5717100_8 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000005279 84.0
HFD2_k127_5717100_9 Tripartite tricarboxylate transporter family receptor - - - 0.0000000262 63.0
HFD2_k127_572033_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.0 1131.0
HFD2_k127_572033_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 0.0 1064.0
HFD2_k127_572033_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006976 504.0
HFD2_k127_572033_11 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 519.0
HFD2_k127_572033_12 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 437.0
HFD2_k127_572033_13 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 422.0
HFD2_k127_572033_14 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 412.0
HFD2_k127_572033_15 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 411.0
HFD2_k127_572033_16 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 414.0
HFD2_k127_572033_17 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009711 387.0
HFD2_k127_572033_18 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 385.0
HFD2_k127_572033_19 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 366.0
HFD2_k127_572033_2 Belongs to the ClpA ClpB family K03695,K03696 - - 6.752e-320 998.0
HFD2_k127_572033_20 Fe-S oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 355.0
HFD2_k127_572033_21 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 371.0
HFD2_k127_572033_22 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 361.0
HFD2_k127_572033_23 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 349.0
HFD2_k127_572033_24 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 353.0
HFD2_k127_572033_25 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 333.0
HFD2_k127_572033_26 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 316.0
HFD2_k127_572033_27 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 319.0
HFD2_k127_572033_28 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 311.0
HFD2_k127_572033_29 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 322.0
HFD2_k127_572033_3 MutS domain I K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 3.518e-229 738.0
HFD2_k127_572033_30 inositol 2-dehydrogenase activity K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 299.0
HFD2_k127_572033_31 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003496 276.0
HFD2_k127_572033_32 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001711 277.0
HFD2_k127_572033_33 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001078 270.0
HFD2_k127_572033_34 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000005514 265.0
HFD2_k127_572033_35 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005219 262.0
HFD2_k127_572033_36 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000002464 264.0
HFD2_k127_572033_37 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000008218 254.0
HFD2_k127_572033_38 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004179 253.0
HFD2_k127_572033_39 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001079 249.0
HFD2_k127_572033_4 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 2.463e-214 680.0
HFD2_k127_572033_40 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000004459 246.0
HFD2_k127_572033_41 pathogenesis K01337,K04771,K20276,K21449 - 3.4.21.107,3.4.21.50 0.0000000000000000000000000000000000000000000000000000000000000000001013 258.0
HFD2_k127_572033_42 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000009532 249.0
HFD2_k127_572033_43 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000003185 227.0
HFD2_k127_572033_44 (Rhomboid) family - - - 0.000000000000000000000000000000000000000000000000000000000000007869 225.0
HFD2_k127_572033_45 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000003567 242.0
HFD2_k127_572033_46 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000005916 226.0
HFD2_k127_572033_47 PFAM binding-protein-dependent transport systems inner membrane component K02042 - - 0.000000000000000000000000000000000000000000000000000000000006152 228.0
HFD2_k127_572033_48 glyoxalase III activity - - - 0.00000000000000000000000000000000000000000000000000000000001066 220.0
HFD2_k127_572033_49 transferase activity, transferring glycosyl groups K02844 - - 0.00000000000000000000000000000000000000000000000000000000001422 221.0
HFD2_k127_572033_5 Type II/IV secretion system protein K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000096 617.0
HFD2_k127_572033_50 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000004435 216.0
HFD2_k127_572033_51 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000006871 218.0
HFD2_k127_572033_52 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02527,K02841,K02843,K12982 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000003408 221.0
HFD2_k127_572033_53 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000002088 211.0
HFD2_k127_572033_54 Cytidylate kinase K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000007307 207.0
HFD2_k127_572033_55 bis(5'-adenosyl)-triphosphatase activity K19710 GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.7.53 0.0000000000000000000000000000000000000000000000004141 179.0
HFD2_k127_572033_56 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000008591 186.0
HFD2_k127_572033_57 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000001106 174.0
HFD2_k127_572033_58 Protein of unknown function (DUF1566) - - - 0.000000000000000000000000000000000000000000000548 190.0
HFD2_k127_572033_59 3-Demethylubiquinone-9 3-methyltransferase K04750 - - 0.00000000000000000000000000000000000000000001265 166.0
HFD2_k127_572033_6 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 579.0
HFD2_k127_572033_60 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000003951 166.0
HFD2_k127_572033_61 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K01090 - 3.1.3.16 0.000000000000000000000000000000000000000001152 176.0
HFD2_k127_572033_62 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000006207 175.0
HFD2_k127_572033_63 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000215 158.0
HFD2_k127_572033_64 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000003012 156.0
HFD2_k127_572033_65 Psort location Cytoplasmic, score 8.96 K09949 - - 0.00000000000000000000000000000000000001406 166.0
HFD2_k127_572033_66 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000273 155.0
HFD2_k127_572033_67 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000005731 147.0
HFD2_k127_572033_68 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000005032 138.0
HFD2_k127_572033_69 CDP-alcohol phosphatidyltransferase K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000001222 139.0
HFD2_k127_572033_7 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 588.0
HFD2_k127_572033_70 transferase activity, transferring glycosyl groups K00754 - - 0.0000000000000000000000000000000001254 148.0
HFD2_k127_572033_71 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves - - - 0.0000000000000000000000000000000002799 151.0
HFD2_k127_572033_72 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000002853 144.0
HFD2_k127_572033_73 PFAM Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000001172 131.0
HFD2_k127_572033_74 regulation of translation K05788 - - 0.00000000000000000000000000000001968 129.0
HFD2_k127_572033_75 PFAM peptidase - - - 0.0000000000000000000000000000008595 134.0
HFD2_k127_572033_76 Regulatory protein - - - 0.0000000000000000000000001842 109.0
HFD2_k127_572033_77 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000003278 104.0
HFD2_k127_572033_78 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000002383 88.0
HFD2_k127_572033_79 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.00000000000000001505 97.0
HFD2_k127_572033_8 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009653 556.0
HFD2_k127_572033_80 SMART helix-turn-helix domain protein - - - 0.0000000000006334 76.0
HFD2_k127_572033_81 Protein of unknown function (DUF1328) - - - 0.00000000005745 66.0
HFD2_k127_572033_82 Subtilase family K14645 - - 0.0000000008034 72.0
HFD2_k127_572033_83 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000001886 55.0
HFD2_k127_572033_85 Major facilitator Superfamily - - - 0.000005312 50.0
HFD2_k127_572033_86 Trypsin-like peptidase domain K01337 - 3.4.21.50 0.00001575 55.0
HFD2_k127_572033_9 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 551.0
HFD2_k127_5810725_0 Adenylate and Guanylate cyclase catalytic domain - - - 6.082e-284 909.0
HFD2_k127_5810725_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 3.149e-263 837.0
HFD2_k127_5810725_10 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001563 283.0
HFD2_k127_5810725_11 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003142 289.0
HFD2_k127_5810725_12 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007505 278.0
HFD2_k127_5810725_13 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006743 286.0
HFD2_k127_5810725_14 NADPH-dependent FMN reductase K19784 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004169 265.0
HFD2_k127_5810725_15 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000338 263.0
HFD2_k127_5810725_16 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008121 252.0
HFD2_k127_5810725_17 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K19819 - 1.5.99.4 0.00000000000000000000000000000000000000000000000000005642 197.0
HFD2_k127_5810725_18 CO dehydrogenase flavoprotein C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000005764 206.0
HFD2_k127_5810725_19 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518,K13483 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000874 185.0
HFD2_k127_5810725_2 Berberine and berberine like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 568.0
HFD2_k127_5810725_20 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000001217 172.0
HFD2_k127_5810725_21 Belongs to the mandelate racemase muconate lactonizing enzyme family K01684 - 4.2.1.6 0.0000000000000000000000000000000521 129.0
HFD2_k127_5810725_22 oxidoreductase activity, acting on CH-OH group of donors K09386 - - 0.0000000000000000000000000001376 120.0
HFD2_k127_5810725_23 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.00000000000000000000000001567 122.0
HFD2_k127_5810725_24 - K11477 - - 0.00000000000000000000000427 106.0
HFD2_k127_5810725_25 Methyltransferase domain K07003 - - 0.0000000000000000000006174 106.0
HFD2_k127_5810725_26 Regulator of chromosome condensation (RCC1) repeat - - - 0.00000000000001487 87.0
HFD2_k127_5810725_3 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 567.0
HFD2_k127_5810725_4 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007432 551.0
HFD2_k127_5810725_5 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 513.0
HFD2_k127_5810725_6 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 401.0
HFD2_k127_5810725_7 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 395.0
HFD2_k127_5810725_8 ABC transporter permease K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 299.0
HFD2_k127_5810725_9 membrane K07148 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000786 318.0
HFD2_k127_5844493_0 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 355.0
HFD2_k127_5844493_1 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 345.0
HFD2_k127_5844493_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009224 287.0
HFD2_k127_5844493_3 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000427 275.0
HFD2_k127_5844493_4 - - - - 0.000000000000000000000000000000000000000000000000004229 189.0
HFD2_k127_5844493_5 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000001938 185.0
HFD2_k127_5844493_6 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000008776 164.0
HFD2_k127_5844493_7 MaoC like domain - - - 0.000000000000000000000000000000000000005241 158.0
HFD2_k127_5844493_8 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000301 96.0
HFD2_k127_5871878_0 Molydopterin dinucleotide binding domain K00123,K05299 - 1.17.1.10,1.17.1.9 0.0 1333.0
HFD2_k127_5871878_1 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0 1082.0
HFD2_k127_5871878_10 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 516.0
HFD2_k127_5871878_11 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 475.0
HFD2_k127_5871878_12 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 481.0
HFD2_k127_5871878_13 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 433.0
HFD2_k127_5871878_14 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000534 402.0
HFD2_k127_5871878_15 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 391.0
HFD2_k127_5871878_16 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005312 387.0
HFD2_k127_5871878_17 NADH dehydrogenase K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005367 396.0
HFD2_k127_5871878_18 NmrA-like family K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009644 381.0
HFD2_k127_5871878_19 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 380.0
HFD2_k127_5871878_2 succinate dehydrogenase, flavoprotein subunit K00239 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4 4.164e-290 914.0
HFD2_k127_5871878_20 Copper resistance protein D K07245 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 387.0
HFD2_k127_5871878_21 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 349.0
HFD2_k127_5871878_22 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009249,GO:0009898,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 327.0
HFD2_k127_5871878_23 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 310.0
HFD2_k127_5871878_24 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 316.0
HFD2_k127_5871878_25 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 313.0
HFD2_k127_5871878_26 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001783 303.0
HFD2_k127_5871878_27 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001468 275.0
HFD2_k127_5871878_28 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003371 275.0
HFD2_k127_5871878_29 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000626 262.0
HFD2_k127_5871878_3 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 5.544e-240 764.0
HFD2_k127_5871878_30 Hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit K01678 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000002409 246.0
HFD2_k127_5871878_31 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000003017 264.0
HFD2_k127_5871878_32 Belongs to the malate synthase family K01638 - 2.3.3.9 0.000000000000000000000000000000000000000000000000000000000000000000006021 256.0
HFD2_k127_5871878_33 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01560,K07025,K20862 - 3.1.3.102,3.1.3.104,3.8.1.2 0.00000000000000000000000000000000000000000000000000000000001643 213.0
HFD2_k127_5871878_34 Carotenoid biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000007873 213.0
HFD2_k127_5871878_35 2Fe-2S iron-sulfur cluster binding domain K00245 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000004841 215.0
HFD2_k127_5871878_36 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K05305,K16881 - 2.7.1.52,2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000001398 209.0
HFD2_k127_5871878_37 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000007949 193.0
HFD2_k127_5871878_38 intermembrane phospholipid transfer K07323 - - 0.000000000000000000000000000000000000000000000000002109 192.0
HFD2_k127_5871878_39 Histidine triad (Hit) protein K02503 - - 0.000000000000000000000000000000000000000000000000005078 193.0
HFD2_k127_5871878_4 elongation factor G K02355 - - 1.514e-222 712.0
HFD2_k127_5871878_40 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000000000001924 192.0
HFD2_k127_5871878_41 MlaD protein K02067 - - 0.0000000000000000000000000000000000000001263 161.0
HFD2_k127_5871878_42 Uncharacterised MFS-type transporter YbfB - - - 0.000000000000000000000000000000000002831 158.0
HFD2_k127_5871878_43 IA, variant 3 - - - 0.00000000000000000000005279 108.0
HFD2_k127_5871878_44 - - - - 0.0000000000000000000009234 99.0
HFD2_k127_5871878_45 PFAM Formiminotransferase-cyclodeaminase - - - 0.0000000000000000004868 95.0
HFD2_k127_5871878_46 Phosphorylase superfamily K01243 - 3.2.2.9 0.000000000000002058 87.0
HFD2_k127_5871878_47 Redoxin domain protein - - - 0.00000000002167 68.0
HFD2_k127_5871878_48 Thioredoxin-like K02199 - - 0.00000001724 59.0
HFD2_k127_5871878_49 Lipid A 3-O-deacylase (PagL) - - - 0.0000001365 64.0
HFD2_k127_5871878_5 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 9.206e-212 675.0
HFD2_k127_5871878_6 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 4.665e-197 638.0
HFD2_k127_5871878_7 Converts isocitrate to alpha ketoglutarate K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005363 606.0
HFD2_k127_5871878_8 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239,K00244 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 600.0
HFD2_k127_5871878_9 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 561.0
HFD2_k127_5875707_0 Thiamine pyrophosphate enzyme, central domain - - - 1.935e-205 655.0
HFD2_k127_5875707_1 PQQ-like domain - - - 6.05e-199 644.0
HFD2_k127_5875707_10 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 372.0
HFD2_k127_5875707_11 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 339.0
HFD2_k127_5875707_12 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 311.0
HFD2_k127_5875707_13 lytic transglycosylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 330.0
HFD2_k127_5875707_14 capsule polysaccharide biosynthetic process K13687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001221 284.0
HFD2_k127_5875707_15 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001697 254.0
HFD2_k127_5875707_16 Glycosyltransferase family 10 (fucosyltransferase) C-term K20151 - 2.4.1.152,2.4.1.65 0.000000000000000000000000000000000000000000000000000000000000000000002373 249.0
HFD2_k127_5875707_17 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000001465 179.0
HFD2_k127_5875707_18 Binding-protein-dependent transport system inner membrane component K02053 - - 0.000000000000000000000000000000000000000000002652 176.0
HFD2_k127_5875707_19 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000005804 184.0
HFD2_k127_5875707_2 Protein of unknown function (DUF917) K09703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 512.0
HFD2_k127_5875707_20 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000497 171.0
HFD2_k127_5875707_3 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 492.0
HFD2_k127_5875707_4 C-methyltransferase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 484.0
HFD2_k127_5875707_5 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 475.0
HFD2_k127_5875707_6 cyclopropane-fatty-acyl-phospholipid synthase K00574,K18827 - 2.1.1.294,2.1.1.79,2.7.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 458.0
HFD2_k127_5875707_7 TIGRFAM glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 436.0
HFD2_k127_5875707_8 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 417.0
HFD2_k127_5875707_9 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 373.0
HFD2_k127_5899554_0 GTP-binding protein TypA K06207 - - 5.447e-260 815.0
HFD2_k127_5899554_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 4.946e-207 674.0
HFD2_k127_5899554_10 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02045,K02049,K02068,K02071,K06857,K10112,K11072 - 3.6.3.25,3.6.3.30,3.6.3.31,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009489 317.0
HFD2_k127_5899554_11 molybdate ABC transporter, permease protein K02017,K02018 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000004932 238.0
HFD2_k127_5899554_12 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000002866 213.0
HFD2_k127_5899554_13 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000008576 210.0
HFD2_k127_5899554_14 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000002684 192.0
HFD2_k127_5899554_15 Enoyl-(Acyl carrier protein) reductase K00034 - 1.1.1.47 0.00000000000000000000000000000000000000000000000000007709 198.0
HFD2_k127_5899554_16 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000001731 182.0
HFD2_k127_5899554_17 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768,K09565 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.000000000000000000000000000000000000000000002187 190.0
HFD2_k127_5899554_18 Protein of unknown function (DUF1566) - - - 0.00000000000000000000000000000000000000008222 168.0
HFD2_k127_5899554_19 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000357 145.0
HFD2_k127_5899554_2 Cache domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 640.0
HFD2_k127_5899554_20 PFAM response regulator receiver K11443 - - 0.00000000000000000000000000003266 131.0
HFD2_k127_5899554_22 PFAM regulatory protein LysR K02019 - - 0.00000000000005382 78.0
HFD2_k127_5899554_23 - K09794 - - 0.00008779 49.0
HFD2_k127_5899554_3 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006725 481.0
HFD2_k127_5899554_4 Adenylosuccinate lyase C-terminus K01756,K01857 - 4.3.2.2,5.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 413.0
HFD2_k127_5899554_5 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009695 352.0
HFD2_k127_5899554_6 Histone deacetylase domain K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 361.0
HFD2_k127_5899554_7 Short-chain dehydrogenase reductase (SDR) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 315.0
HFD2_k127_5899554_8 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 301.0
HFD2_k127_5899554_9 Belongs to the ABC transporter superfamily K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 320.0
HFD2_k127_5914784_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 595.0
HFD2_k127_5914784_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 452.0
HFD2_k127_5914784_10 cation diffusion facilitator family transporter - - - 0.0001125 48.0
HFD2_k127_5914784_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 420.0
HFD2_k127_5914784_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 307.0
HFD2_k127_5914784_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 290.0
HFD2_k127_5914784_5 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000006638 221.0
HFD2_k127_5914784_6 FKBP-type peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.000000000000000000000000000000007865 144.0
HFD2_k127_5914784_7 Lysyl oxidase - - - 0.0000000000000000000000000003845 124.0
HFD2_k127_5914784_8 PAS fold K02484 - 2.7.13.3 0.00000000000000000000000427 105.0
HFD2_k127_5914784_9 AsmA-like C-terminal region K07289 - - 0.000000151 64.0
HFD2_k127_6015930_0 Belongs to the LDH2 MDH2 oxidoreductase family K16844 - 1.1.1.338 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 402.0
HFD2_k127_6015930_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 396.0
HFD2_k127_6015930_10 Major facilitator superfamily - - - 0.0000000000000000000000000000000613 139.0
HFD2_k127_6015930_2 Beta-lactamase class A K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 310.0
HFD2_k127_6015930_3 NAD(P)-binding Rossmann-like domain K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 319.0
HFD2_k127_6015930_4 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000004494 228.0
HFD2_k127_6015930_5 Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively K04099,K04101 - 1.13.11.57,1.13.11.8 0.000000000000000000000000000000000000000000000000000000006341 207.0
HFD2_k127_6015930_6 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000007015 184.0
HFD2_k127_6015930_7 dehydratase - - - 0.0000000000000000000000000000000000000000000326 165.0
HFD2_k127_6015930_8 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000002899 160.0
HFD2_k127_6015930_9 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000001597 162.0
HFD2_k127_602951_0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 0.0 1010.0
HFD2_k127_602951_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 7.893e-298 930.0
HFD2_k127_602951_10 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000002745 178.0
HFD2_k127_602951_12 TIGRFAM FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family K20938 - 1.14.14.28 0.00000000000000000000000000001567 138.0
HFD2_k127_602951_13 Cupin 4 family protein K18850 - 1.14.11.47 0.000001416 61.0
HFD2_k127_602951_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 602.0
HFD2_k127_602951_3 Belongs to the Glu Leu Phe Val dehydrogenases family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 505.0
HFD2_k127_602951_4 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 397.0
HFD2_k127_602951_5 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005388 320.0
HFD2_k127_602951_6 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 294.0
HFD2_k127_602951_7 Amino acid synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007113 261.0
HFD2_k127_602951_8 Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001109 273.0
HFD2_k127_602951_9 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000003105 192.0
HFD2_k127_6076992_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1124.0
HFD2_k127_6076992_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 566.0
HFD2_k127_6076992_10 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005129 260.0
HFD2_k127_6076992_11 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000000000005964 238.0
HFD2_k127_6076992_12 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000001525 197.0
HFD2_k127_6076992_13 Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively K04101 - 1.13.11.8 0.0000000000000000000000000000000000000000000000008492 186.0
HFD2_k127_6076992_14 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000001898 171.0
HFD2_k127_6076992_15 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000004454 109.0
HFD2_k127_6076992_17 - - - - 0.0000009809 60.0
HFD2_k127_6076992_2 Iron permease FTR1 K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006822 563.0
HFD2_k127_6076992_3 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 504.0
HFD2_k127_6076992_4 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009949 481.0
HFD2_k127_6076992_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 490.0
HFD2_k127_6076992_6 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 419.0
HFD2_k127_6076992_7 4-phosphoerythronate dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 407.0
HFD2_k127_6076992_8 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01684 - 4.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 404.0
HFD2_k127_6076992_9 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 370.0
HFD2_k127_6099845_0 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008181 327.0
HFD2_k127_6099845_1 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 311.0
HFD2_k127_6099845_2 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000001332 223.0
HFD2_k127_6099845_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000003542 58.0
HFD2_k127_6160122_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 3.751e-250 789.0
HFD2_k127_6160122_1 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000889 490.0
HFD2_k127_6160122_10 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.000000000000000000000000000000001584 138.0
HFD2_k127_6160122_11 metallopeptidase activity - - - 0.000000000001917 79.0
HFD2_k127_6160122_2 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 428.0
HFD2_k127_6160122_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 431.0
HFD2_k127_6160122_4 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 362.0
HFD2_k127_6160122_5 Hydrogenase expression formation protein (HypE) K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 323.0
HFD2_k127_6160122_6 COG3842 ABC-type spermidine putrescine transport systems, ATPase components K02010,K02017,K15497 - 3.6.3.29,3.6.3.30,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 316.0
HFD2_k127_6160122_7 Formiminotransferase domain, N-terminal subdomain K00603 - 2.1.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000529 265.0
HFD2_k127_6160122_8 Rhs element vgr protein - - - 0.00000000000000000000000000000000000000000000000000253 194.0
HFD2_k127_6160122_9 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000007606 153.0
HFD2_k127_6185930_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 537.0
HFD2_k127_6185930_1 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K17763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 416.0
HFD2_k127_6185930_10 proline dehydrogenase activity K00318 - - 0.00000000000000000000000000000000000000000000000000000006368 218.0
HFD2_k127_6185930_11 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000002953 203.0
HFD2_k127_6185930_12 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000004732 213.0
HFD2_k127_6185930_13 Lipopolysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000001546 207.0
HFD2_k127_6185930_14 Protein of unknown function (DUF1698) - - - 0.000000000000000000000000000000000000000000000000001645 207.0
HFD2_k127_6185930_15 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000005397 207.0
HFD2_k127_6185930_16 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000135 197.0
HFD2_k127_6185930_17 Stage II sporulation protein E K05518 - 3.1.3.3 0.0000000000000000000000000000000000000000000008322 179.0
HFD2_k127_6185930_18 STAS domain K17762 - - 0.0000000000000000000000000000000000000000008816 159.0
HFD2_k127_6185930_19 Protein of unknown function (DUF1566) - - - 0.00000000000000000000000000000000000000005912 173.0
HFD2_k127_6185930_2 PFAM aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 321.0
HFD2_k127_6185930_20 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000001856 166.0
HFD2_k127_6185930_21 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000000003424 161.0
HFD2_k127_6185930_22 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07675 - 2.7.13.3 0.00000000000000000000000000000000000786 154.0
HFD2_k127_6185930_23 Histidine kinase-like ATPases K17752 - 2.7.11.1 0.00000000000000000000000000000000001509 154.0
HFD2_k127_6185930_24 Capsular exopolysaccharide family K08252 - 2.7.10.1 0.0000000000000000000000000000004009 143.0
HFD2_k127_6185930_25 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000008669 126.0
HFD2_k127_6185930_26 helix_turn_helix, Lux Regulon K11618 - - 0.00000000000000000000000000002276 123.0
HFD2_k127_6185930_27 Heparinase II/III N-terminus - - - 0.00000000000000000000008021 114.0
HFD2_k127_6185930_28 O-antigen ligase like membrane protein - - - 0.00000000000000002432 98.0
HFD2_k127_6185930_3 Protein involved in cellulose biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 304.0
HFD2_k127_6185930_4 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007609 290.0
HFD2_k127_6185930_5 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000013 277.0
HFD2_k127_6185930_6 SMART AAA ATPase K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009603 257.0
HFD2_k127_6185930_7 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000853 271.0
HFD2_k127_6185930_8 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000006753 237.0
HFD2_k127_6185930_9 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000166 209.0
HFD2_k127_6189311_0 Tricorn protease PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 497.0
HFD2_k127_6189311_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001584 289.0
HFD2_k127_6189311_2 transcriptional activator domain - - - 0.0000000000000000000000000009437 131.0
HFD2_k127_6192634_0 Glutamate synthase central domain K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2190.0
HFD2_k127_6192634_1 Flavin containing amine oxidoreductase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 3.794e-255 793.0
HFD2_k127_6192634_10 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 385.0
HFD2_k127_6192634_11 COG0583 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001734 284.0
HFD2_k127_6192634_12 peroxidase activity K00435 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004723 281.0
HFD2_k127_6192634_13 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003143 272.0
HFD2_k127_6192634_14 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003313 252.0
HFD2_k127_6192634_15 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000001968 170.0
HFD2_k127_6192634_16 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000006024 166.0
HFD2_k127_6192634_17 transmembrane transport K03442 - - 0.00000000000000000000000000000000009846 140.0
HFD2_k127_6192634_18 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.000000000000000000000000003502 121.0
HFD2_k127_6192634_19 Cupin domain - - - 0.0000000000000000000000001083 113.0
HFD2_k127_6192634_2 Pyruvate flavodoxin ferredoxin K00174 - 1.2.7.11,1.2.7.3 2.638e-237 748.0
HFD2_k127_6192634_20 LUD domain K00782,K18929 - - 0.000000000000000000000001453 121.0
HFD2_k127_6192634_21 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000007927 89.0
HFD2_k127_6192634_22 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.000000000000002003 88.0
HFD2_k127_6192634_23 - - - - 0.00000001747 56.0
HFD2_k127_6192634_3 Gaf domain - - - 2.617e-201 658.0
HFD2_k127_6192634_4 FAD linked oxidases, C-terminal domain K00102,K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.2.4,1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 531.0
HFD2_k127_6192634_5 Domain of unknown function (DUF3390) K18929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 477.0
HFD2_k127_6192634_6 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 456.0
HFD2_k127_6192634_7 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009981 460.0
HFD2_k127_6192634_8 Cysteine-rich domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 426.0
HFD2_k127_6192634_9 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 407.0
HFD2_k127_6193167_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016903,GO:0030151,GO:0033554,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114 1.17.1.4 0.0 1081.0
HFD2_k127_6193167_1 RESPONSE REGULATOR receiver - - - 1.575e-195 616.0
HFD2_k127_6193167_2 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 406.0
HFD2_k127_6193167_3 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005484 275.0
HFD2_k127_6193167_4 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000007117 147.0
HFD2_k127_6193167_5 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000005476 106.0
HFD2_k127_6193167_6 SMART Rhodanese domain protein - - - 0.00000000000000002919 89.0
HFD2_k127_6193167_7 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000006417 81.0
HFD2_k127_6193167_8 ThiS family K03636 - - 0.00000000000001631 77.0
HFD2_k127_6206421_0 Glycosyl transferases group 1 K19424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 456.0
HFD2_k127_6206421_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000009307 244.0
HFD2_k127_6206421_2 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000006021 158.0
HFD2_k127_6206421_3 O-Antigen Polymerase K02847 - - 0.0000000000000000000000000000009673 139.0
HFD2_k127_6206421_4 FemAB family - - - 0.0000000000000000000000001999 118.0
HFD2_k127_6210358_0 aminotransferase class I and II K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003871 265.0
HFD2_k127_6210358_1 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000000000000000000000000000002846 172.0
HFD2_k127_6221477_0 copper-translocating P-type ATPase K17686 - 3.6.3.54 8.304e-318 992.0
HFD2_k127_6221477_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 5.676e-288 910.0
HFD2_k127_6221477_10 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 475.0
HFD2_k127_6221477_11 PFAM Type II secretion system protein E K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 489.0
HFD2_k127_6221477_12 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 458.0
HFD2_k127_6221477_13 PFAM type II secretion system protein E K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 431.0
HFD2_k127_6221477_14 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 424.0
HFD2_k127_6221477_15 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 385.0
HFD2_k127_6221477_16 PFAM FAD linked oxidase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 385.0
HFD2_k127_6221477_17 PFAM Na Picotransporter K03324 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006608 384.0
HFD2_k127_6221477_18 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006028 374.0
HFD2_k127_6221477_19 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 384.0
HFD2_k127_6221477_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 8.853e-206 677.0
HFD2_k127_6221477_20 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043919,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 353.0
HFD2_k127_6221477_21 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 344.0
HFD2_k127_6221477_22 Belongs to the DegT DnrJ EryC1 family K13017 - 2.6.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007975 346.0
HFD2_k127_6221477_23 SMART PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 324.0
HFD2_k127_6221477_24 Glycosyltransferase family 28 N-terminal domain K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 310.0
HFD2_k127_6221477_25 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 302.0
HFD2_k127_6221477_26 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006893 297.0
HFD2_k127_6221477_27 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000179 287.0
HFD2_k127_6221477_28 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002693 274.0
HFD2_k127_6221477_29 nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000341 267.0
HFD2_k127_6221477_3 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 580.0
HFD2_k127_6221477_30 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000009633 277.0
HFD2_k127_6221477_31 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000001047 235.0
HFD2_k127_6221477_32 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000006636 226.0
HFD2_k127_6221477_33 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000006039 238.0
HFD2_k127_6221477_34 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000238 207.0
HFD2_k127_6221477_35 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000001781 189.0
HFD2_k127_6221477_36 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000000000001141 198.0
HFD2_k127_6221477_37 Secretin and TonB N terminus short domain K02666 - - 0.00000000000000000000000000000000000000000000000007046 199.0
HFD2_k127_6221477_38 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000006127 192.0
HFD2_k127_6221477_39 Mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000000000000000000001796 197.0
HFD2_k127_6221477_4 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 586.0
HFD2_k127_6221477_40 Peptidase C13 family - - - 0.00000000000000000000000000000000000000000000001385 194.0
HFD2_k127_6221477_41 PAS domain K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000137 175.0
HFD2_k127_6221477_42 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000002187 169.0
HFD2_k127_6221477_43 Nitrogen regulatory protein P-II K04751 - - 0.000000000000000000000000000000000000000004599 177.0
HFD2_k127_6221477_44 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.00000000000000000000000000000000000000003581 163.0
HFD2_k127_6221477_45 Belongs to the PdaD family K02626 - 4.1.1.19 0.00000000000000000000000000000000000001421 154.0
HFD2_k127_6221477_46 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000000000000000000000000000002012 139.0
HFD2_k127_6221477_47 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000005515 134.0
HFD2_k127_6221477_48 Tellurite resistance protein TehB - - - 0.000000000000000000000000000007728 126.0
HFD2_k127_6221477_49 phosphoglycerate mutase K02226 - 3.1.3.73 0.0000000000000000000000000001068 131.0
HFD2_k127_6221477_5 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 548.0
HFD2_k127_6221477_50 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000002384 124.0
HFD2_k127_6221477_51 Methyltransferase domain - - - 0.0000000000000000000000005085 121.0
HFD2_k127_6221477_52 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000002177 108.0
HFD2_k127_6221477_53 Cytochrome c K17222 - - 0.000000000000000000001643 108.0
HFD2_k127_6221477_54 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.0000000000000000001411 101.0
HFD2_k127_6221477_55 PFAM Copper resistance protein CopC K07156 - - 0.0000000000000000004482 98.0
HFD2_k127_6221477_56 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000007402 95.0
HFD2_k127_6221477_57 response to copper ion K07156 - - 0.0000000000002251 78.0
HFD2_k127_6221477_58 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000002867 78.0
HFD2_k127_6221477_59 - - - - 0.000002071 59.0
HFD2_k127_6221477_6 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007042 547.0
HFD2_k127_6221477_7 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 490.0
HFD2_k127_6221477_8 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 495.0
HFD2_k127_6221477_9 AAA ATPase K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 492.0
HFD2_k127_622772_0 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic K01886 - 6.1.1.18 4.962e-279 866.0
HFD2_k127_622772_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 2.626e-268 840.0
HFD2_k127_622772_10 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002831 269.0
HFD2_k127_622772_11 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000001445 252.0
HFD2_k127_622772_12 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate - - - 0.000000000000000000000000000000000000000000000000000000000000001083 224.0
HFD2_k127_622772_13 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000001585 225.0
HFD2_k127_622772_14 Protein of unknown function (DUF1566) - - - 0.00000000000000000000000000000000000000000002321 187.0
HFD2_k127_622772_15 Sigma-70, region 4 - - - 0.000000000000000000000000000000000000008521 155.0
HFD2_k127_622772_16 Putative zinc-finger - - - 0.000000000000000000002573 105.0
HFD2_k127_622772_17 membrane - - - 0.0000000000005951 81.0
HFD2_k127_622772_2 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404,K03405 - 6.6.1.1 1.295e-208 658.0
HFD2_k127_622772_3 Aconitase family (aconitate hydratase) - - - 1.619e-194 616.0
HFD2_k127_622772_4 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 565.0
HFD2_k127_622772_5 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 498.0
HFD2_k127_622772_6 PFAM dehydrogenase E1 component K21416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 464.0
HFD2_k127_622772_7 PFAM Transketolase central region K21417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 419.0
HFD2_k127_622772_8 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01003,K01841 - 4.1.1.3,5.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 420.0
HFD2_k127_622772_9 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 301.0
HFD2_k127_6246437_0 Proline dehydrogenase K13821 - 1.2.1.88,1.5.5.2 0.0 1107.0
HFD2_k127_6246437_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 4.349e-282 881.0
HFD2_k127_6246437_10 drug resistance transporter, EmrB QacA subfamily K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 376.0
HFD2_k127_6246437_11 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 355.0
HFD2_k127_6246437_12 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 336.0
HFD2_k127_6246437_13 Luciferase-like monooxygenase K15510 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.98.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957 312.0
HFD2_k127_6246437_14 cyclase dehydrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 292.0
HFD2_k127_6246437_15 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001123 304.0
HFD2_k127_6246437_16 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003887 284.0
HFD2_k127_6246437_17 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002801 282.0
HFD2_k127_6246437_18 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001083 257.0
HFD2_k127_6246437_19 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000007422 243.0
HFD2_k127_6246437_2 amine dehydrogenase activity K03418 - 3.5.1.56 1.183e-258 816.0
HFD2_k127_6246437_20 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000009197 225.0
HFD2_k127_6246437_21 Bacterial regulatory proteins, tetR family K16137 - - 0.00000000000000000000000000000000000000000000000000000000000001113 222.0
HFD2_k127_6246437_22 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000001289 226.0
HFD2_k127_6246437_23 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000003597 222.0
HFD2_k127_6246437_24 PFAM amidohydrolase 2 K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000002896 209.0
HFD2_k127_6246437_25 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000005184 204.0
HFD2_k127_6246437_26 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000006307 198.0
HFD2_k127_6246437_27 acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000002751 202.0
HFD2_k127_6246437_28 PFAM Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000005976 194.0
HFD2_k127_6246437_29 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000003003 191.0
HFD2_k127_6246437_3 DNA-K related protein - - - 1.615e-215 700.0
HFD2_k127_6246437_30 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000001038 179.0
HFD2_k127_6246437_31 DsbA oxidoreductase - - - 0.00000000000000000000000000000000000000000000003498 175.0
HFD2_k127_6246437_32 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000001806 152.0
HFD2_k127_6246437_33 AAA domain - - - 0.000000000000000000000000000000000000002213 151.0
HFD2_k127_6246437_34 - - - - 0.00000000000000000000000000000000000001388 153.0
HFD2_k127_6246437_35 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000008839 144.0
HFD2_k127_6246437_36 Domain of unknown function (DUF2760) - - - 0.0000000000000000000000000000000001025 144.0
HFD2_k127_6246437_37 Predicted membrane protein (DUF2231) - - - 0.000000000000000000000000000000001676 137.0
HFD2_k127_6246437_38 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.000000000000000000000000003326 111.0
HFD2_k127_6246437_39 Cold shock protein K03704 - - 0.00000000000000000000000004663 113.0
HFD2_k127_6246437_4 MreB/Mbl protein - - - 2.995e-214 685.0
HFD2_k127_6246437_40 Transglycosylase associated protein - - - 0.000000000000000000000004091 117.0
HFD2_k127_6246437_41 CoA binding domain - - - 0.0000000000000000000001597 105.0
HFD2_k127_6246437_42 Luciferase-like monooxygenase - - - 0.000000000001762 70.0
HFD2_k127_6246437_43 - - - - 0.00000000001984 66.0
HFD2_k127_6246437_44 Putative peptidoglycan binding domain - - - 0.00000002747 58.0
HFD2_k127_6246437_45 - - - - 0.0000006071 62.0
HFD2_k127_6246437_46 - - - - 0.00001237 55.0
HFD2_k127_6246437_5 PFAM Alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 611.0
HFD2_k127_6246437_7 DNA topoisomerase II activity K03167 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 540.0
HFD2_k127_6246437_8 COG0402 Cytosine deaminase and related metal-dependent hydrolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 507.0
HFD2_k127_6246437_9 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009971 426.0
HFD2_k127_6257528_0 Glycosyl transferases group 1 K19424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 423.0
HFD2_k127_6257528_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001741 243.0
HFD2_k127_6257528_2 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000003955 156.0
HFD2_k127_6269946_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 421.0
HFD2_k127_6269946_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000006342 197.0
HFD2_k127_6296936_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 404.0
HFD2_k127_6296936_1 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000002666 244.0
HFD2_k127_6317634_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.608e-249 783.0
HFD2_k127_6317634_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.947e-230 727.0
HFD2_k127_6317634_10 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 390.0
HFD2_k127_6317634_11 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 348.0
HFD2_k127_6317634_12 TIGRFAM amidase, hydantoinase carbamoylase K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 347.0
HFD2_k127_6317634_13 Ethanolamine utilization protein EutJ K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 337.0
HFD2_k127_6317634_14 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 310.0
HFD2_k127_6317634_15 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 295.0
HFD2_k127_6317634_16 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007185 291.0
HFD2_k127_6317634_17 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005477 285.0
HFD2_k127_6317634_18 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001061 281.0
HFD2_k127_6317634_19 ATPases associated with a variety of cellular activities K05847 GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0031460,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0072337 - 0.000000000000000000000000000000000000000000000000000000000000000000000001102 255.0
HFD2_k127_6317634_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.132,1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006702 575.0
HFD2_k127_6317634_20 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007047 256.0
HFD2_k127_6317634_21 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000002713 237.0
HFD2_k127_6317634_22 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000003609 252.0
HFD2_k127_6317634_23 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000005727 239.0
HFD2_k127_6317634_24 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000001183 225.0
HFD2_k127_6317634_25 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000001699 210.0
HFD2_k127_6317634_26 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594,K07052 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000001333 207.0
HFD2_k127_6317634_27 PFAM glutamine amidotransferase class-I K07010 - - 0.000000000000000000000000000000000000000000000000005452 207.0
HFD2_k127_6317634_28 UbiA prenyltransferase family K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000009724 174.0
HFD2_k127_6317634_29 protein required for cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000000009127 133.0
HFD2_k127_6317634_3 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007821 597.0
HFD2_k127_6317634_30 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.00000000000000000000000000006543 134.0
HFD2_k127_6317634_31 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000000000004233 82.0
HFD2_k127_6317634_32 VIT family - - - 0.000000000000004128 85.0
HFD2_k127_6317634_33 Trm112p-like protein K09791 - - 0.000000000009296 70.0
HFD2_k127_6317634_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000419 545.0
HFD2_k127_6317634_5 response to heat K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007733 479.0
HFD2_k127_6317634_6 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 489.0
HFD2_k127_6317634_7 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 462.0
HFD2_k127_6317634_8 DinB superfamily K18912 - 1.14.99.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 415.0
HFD2_k127_6317634_9 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 414.0
HFD2_k127_6325052_0 Aldo Keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 452.0
HFD2_k127_6325052_1 Sugar (and other) transporter K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 384.0
HFD2_k127_6325052_2 phosphogluconate dehydrogenase (decarboxylating) activity K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000898 358.0
HFD2_k127_6325052_3 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008045 344.0
HFD2_k127_6325052_4 decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000001773 128.0
HFD2_k127_6325052_5 - - - - 0.000000000000004661 81.0
HFD2_k127_6328446_0 Hydantoinase/oxoprolinase - - - 5.767e-264 831.0
HFD2_k127_6328446_1 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 2.834e-236 751.0
HFD2_k127_6328446_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 2.998e-219 718.0
HFD2_k127_6328446_3 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 568.0
HFD2_k127_6328446_4 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009227 378.0
HFD2_k127_6328446_5 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 308.0
HFD2_k127_6328446_7 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000001218 239.0
HFD2_k127_6328446_8 serine-type endopeptidase activity K04772,K08372 - - 0.0000000000000000000001651 110.0
HFD2_k127_6328446_9 SMP-30/Gluconolaconase/LRE-like region K02352 - - 0.0000000008438 61.0
HFD2_k127_6328519_0 Proton-conducting membrane transporter K00342,K05575 - 1.6.5.3 1.108e-205 655.0
HFD2_k127_6328519_1 NADH-quinone oxidoreductase chain L K00341,K05577 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 557.0
HFD2_k127_6328519_10 NIPSNAP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004426 249.0
HFD2_k127_6328519_11 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000254 241.0
HFD2_k127_6328519_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000002359 224.0
HFD2_k127_6328519_13 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000001248 165.0
HFD2_k127_6328519_14 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000005149 144.0
HFD2_k127_6328519_15 4Fe-4S dicluster domain K00338,K02573,K03941 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000001032 149.0
HFD2_k127_6328519_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.000000000000000000000000000003149 124.0
HFD2_k127_6328519_17 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.000000000000000000000002333 116.0
HFD2_k127_6328519_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000004041 105.0
HFD2_k127_6328519_19 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339,K05578 - 1.6.5.3 0.00000000000000000006799 101.0
HFD2_k127_6328519_2 Epoxide hydrolase N terminus K01253 - 3.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008783 531.0
HFD2_k127_6328519_20 hydrolase activity, acting on ester bonds K01563 - 3.8.1.5 0.000000000000000004665 89.0
HFD2_k127_6328519_21 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000108 87.0
HFD2_k127_6328519_22 Redoxin K03564 - 1.11.1.15 0.00000000000001134 74.0
HFD2_k127_6328519_23 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000001221 63.0
HFD2_k127_6328519_3 Cobalamin-independent synthase, Catalytic domain K00549,K22363 - 2.1.1.14,4.4.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 492.0
HFD2_k127_6328519_4 NAD binding K00333,K05579,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 446.0
HFD2_k127_6328519_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337,K05572 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007302 363.0
HFD2_k127_6328519_6 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 323.0
HFD2_k127_6328519_7 amidohydrolase K21613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 313.0
HFD2_k127_6328519_8 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 299.0
HFD2_k127_6328519_9 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 293.0
HFD2_k127_6340636_0 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001783 271.0
HFD2_k127_6346586_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 531.0
HFD2_k127_6346586_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 410.0
HFD2_k127_6346586_10 - - - - 0.0000000000000000000000000000000000000000000000000000000001979 218.0
HFD2_k127_6346586_11 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000007157 77.0
HFD2_k127_6346586_12 Glycosyl transferase, family 2 - - - 0.0000000000002225 72.0
HFD2_k127_6346586_13 - - - - 0.0000000001518 70.0
HFD2_k127_6346586_14 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000003071 61.0
HFD2_k127_6346586_15 COG1413 FOG HEAT repeat K22221 - - 0.00000001903 67.0
HFD2_k127_6346586_16 FR47-like protein - - - 0.000001127 61.0
HFD2_k127_6346586_17 Serine/threonine phosphatases, family 2C, catalytic domain K01090 - 3.1.3.16 0.0003206 49.0
HFD2_k127_6346586_2 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008828 382.0
HFD2_k127_6346586_3 Aminotransferase K11358 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 392.0
HFD2_k127_6346586_4 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 338.0
HFD2_k127_6346586_5 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 338.0
HFD2_k127_6346586_6 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 295.0
HFD2_k127_6346586_7 Hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006216 315.0
HFD2_k127_6346586_8 Anp1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000004799 242.0
HFD2_k127_6346586_9 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000001133 221.0
HFD2_k127_6421028_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 1.763e-292 904.0
HFD2_k127_6421028_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 519.0
HFD2_k127_6421028_10 Belongs to the peptidase S11 family K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000602 180.0
HFD2_k127_6421028_11 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000003344 89.0
HFD2_k127_6421028_12 - - - - 0.0000000000007625 72.0
HFD2_k127_6421028_13 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000001819 61.0
HFD2_k127_6421028_2 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 514.0
HFD2_k127_6421028_3 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009478 441.0
HFD2_k127_6421028_4 Gamma-glutamyltranspeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 360.0
HFD2_k127_6421028_5 ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008279 351.0
HFD2_k127_6421028_6 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002668 259.0
HFD2_k127_6421028_7 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000001409 234.0
HFD2_k127_6421028_8 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000111 215.0
HFD2_k127_6421028_9 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000004273 208.0
HFD2_k127_6428180_0 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 1.159e-202 634.0
HFD2_k127_6428180_1 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 597.0
HFD2_k127_6428180_2 MacB-like periplasmic core domain K02004,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 470.0
HFD2_k127_6428180_3 DNA topoisomerase II activity K03167 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 419.0
HFD2_k127_6428180_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 360.0
HFD2_k127_6428180_5 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 290.0
HFD2_k127_6428180_6 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000001241 179.0
HFD2_k127_6428180_7 17 kDa outer membrane surface antigen - - - 0.0000000000000000000000000000000000009703 145.0
HFD2_k127_6428180_8 EF-hand, calcium binding motif - - - 0.000006179 55.0
HFD2_k127_6429010_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000006176 237.0
HFD2_k127_6429010_1 alpha/beta hydrolase fold - - - 0.0000000000000000000000002228 119.0
HFD2_k127_6429010_2 Alpha beta hydrolase - - - 0.0000000000001316 74.0
HFD2_k127_6446608_0 aminotransferase class I and II K14261 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000809 571.0
HFD2_k127_6446608_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00928,K12524 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 509.0
HFD2_k127_6446608_10 PFAM glycoside hydrolase, family 3 domain protein K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 306.0
HFD2_k127_6446608_11 Acetyl-CoA hydrolase/transferase N-terminal domain K18122 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 317.0
HFD2_k127_6446608_12 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000296 289.0
HFD2_k127_6446608_13 Inosine-uridine preferring nucleoside hydrolase K01239,K01250 - 3.2.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001468 277.0
HFD2_k127_6446608_14 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000459 268.0
HFD2_k127_6446608_15 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002903 253.0
HFD2_k127_6446608_16 photosystem I assembly BtpA K06971 - - 0.000000000000000000000000000000000000000000000000000000000000000000001733 244.0
HFD2_k127_6446608_17 Asparaginase K13051 - 3.4.19.5 0.000000000000000000000000000000000000000000000000000000000000000000004905 248.0
HFD2_k127_6446608_18 Enoyl-(Acyl carrier protein) reductase K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000007185 224.0
HFD2_k127_6446608_19 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000009883 209.0
HFD2_k127_6446608_2 homoserine dehydrogenase K00003 GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 462.0
HFD2_k127_6446608_20 Peptidase, M23 - - - 0.0000000000000000000000000000000000000002874 161.0
HFD2_k127_6446608_21 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000001654 152.0
HFD2_k127_6446608_22 Phosphate acyltransferases - - - 0.00000000000000000000000000000000001649 142.0
HFD2_k127_6446608_23 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000006689 136.0
HFD2_k127_6446608_24 translation initiation inhibitor, yjgF family - - - 0.0000000000000000000000000004979 120.0
HFD2_k127_6446608_25 PFAM Outer membrane lipoprotein Slp K07285 - - 0.000000000000000000000000001283 121.0
HFD2_k127_6446608_26 Competence protein ComEA K02237 - - 0.00000000001137 71.0
HFD2_k127_6446608_27 Threonine dehydratase K01754 - 4.3.1.19 0.000000002269 63.0
HFD2_k127_6446608_29 Contains selenocysteine K07401 - - 0.0000008514 52.0
HFD2_k127_6446608_3 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 460.0
HFD2_k127_6446608_4 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007749 391.0
HFD2_k127_6446608_5 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K09461 - 1.14.13.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 372.0
HFD2_k127_6446608_6 Metallo-beta-lactamase superfamily K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 379.0
HFD2_k127_6446608_7 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 354.0
HFD2_k127_6446608_8 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 314.0
HFD2_k127_6446608_9 Peptidase M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 320.0
HFD2_k127_645042_0 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 330.0
HFD2_k127_645042_1 Thi4 family - - - 0.00000000000000000000000000000000000000000000000000001389 203.0
HFD2_k127_6457157_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1059.0
HFD2_k127_6457157_1 Copper amine oxidase, enzyme domain K00276 - 1.4.3.21 3.07e-260 819.0
HFD2_k127_6457157_2 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 319.0
HFD2_k127_6457157_3 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 304.0
HFD2_k127_6457157_4 (ABC) transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002383 273.0
HFD2_k127_6457157_5 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001629 252.0
HFD2_k127_6457157_6 MaoC like domain - - - 0.0000000000000000000000000000001292 128.0
HFD2_k127_6470893_0 ERAP1-like C-terminal domain K01256 - 3.4.11.2 1.901e-195 624.0
HFD2_k127_6470893_1 cellulose binding - - - 0.0000000000000000000000000000000002678 141.0
HFD2_k127_6513332_0 - - - - 0.00000000000004415 85.0
HFD2_k127_6513332_1 Sulfatase-modifying factor enzyme 1 - - - 0.000003652 51.0
HFD2_k127_6605147_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.069e-203 650.0
HFD2_k127_6605147_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005077 489.0
HFD2_k127_6605147_10 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000005222 137.0
HFD2_k127_6605147_11 Protein of unknown function (DUF983) - - - 0.000000000000000000000000002412 116.0
HFD2_k127_6605147_2 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 443.0
HFD2_k127_6605147_3 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 373.0
HFD2_k127_6605147_4 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 356.0
HFD2_k127_6605147_5 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 327.0
HFD2_k127_6605147_6 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000496 278.0
HFD2_k127_6605147_7 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004885 265.0
HFD2_k127_6605147_8 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000006398 252.0
HFD2_k127_6605147_9 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000002795 209.0
HFD2_k127_6638082_0 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 511.0
HFD2_k127_6638082_1 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 471.0
HFD2_k127_6638082_10 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000001216 64.0
HFD2_k127_6638082_11 Protein of unknown function (DUF1810) - - - 0.00007729 48.0
HFD2_k127_6638082_2 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 440.0
HFD2_k127_6638082_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 351.0
HFD2_k127_6638082_5 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000000000000003719 229.0
HFD2_k127_6638082_6 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000829 209.0
HFD2_k127_6638082_7 Domain of unknown function (DUF4337) - - - 0.00000000000000000000000000000000000000000000002534 189.0
HFD2_k127_6638082_8 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000008983 78.0
HFD2_k127_6638082_9 - - - - 0.0000000000006802 81.0
HFD2_k127_6640736_0 response regulator receiver K02481,K07714,K10943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 420.0
HFD2_k127_6640736_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 381.0
HFD2_k127_6640736_10 Phosphonate ABC transporter K02044 - - 0.000000000000000000000000000000000000000000004998 182.0
HFD2_k127_6640736_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000002285 167.0
HFD2_k127_6640736_12 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000004263 152.0
HFD2_k127_6640736_13 Belongs to the HesB IscA family K13628,K15724 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055114,GO:0071704,GO:0071840,GO:0071944,GO:1901564 - 0.0000000000000000000000000001572 118.0
HFD2_k127_6640736_14 alpha beta - - - 0.0000000000000000000000000612 119.0
HFD2_k127_6640736_15 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000004831 117.0
HFD2_k127_6640736_16 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000002781 100.0
HFD2_k127_6640736_2 PFAM phosphoesterase, RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 337.0
HFD2_k127_6640736_3 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005827 271.0
HFD2_k127_6640736_4 GTP cyclohydrolase I K00950,K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000002745 259.0
HFD2_k127_6640736_5 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000001424 260.0
HFD2_k127_6640736_6 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003231 258.0
HFD2_k127_6640736_7 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001057 254.0
HFD2_k127_6640736_8 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000724 240.0
HFD2_k127_6640736_9 Molybdopterin converting factor subunit K03635,K21142 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000003196 214.0
HFD2_k127_6751145_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000009328 244.0
HFD2_k127_6751145_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000002237 192.0
HFD2_k127_6831094_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase K00483 - 1.14.14.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 419.0
HFD2_k127_6831094_1 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 390.0
HFD2_k127_6831094_2 Carboxylesterase K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002527 262.0
HFD2_k127_6831094_3 'PFAM Taurine catabolism dioxygenase TauD, TfdA family' - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004601 260.0
HFD2_k127_6831094_4 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009643 258.0
HFD2_k127_6831094_5 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000002204 250.0
HFD2_k127_6831094_6 membrane - - - 0.0000000000000000000000000000000000000001895 153.0
HFD2_k127_6831094_7 Phospholipase/Carboxylesterase K06999 - - 0.000000000000009246 74.0
HFD2_k127_6831094_8 Bacterial extracellular solute-binding protein K17329 - - 0.000000000000547 81.0
HFD2_k127_6831094_9 membrane - - - 0.00005606 56.0
HFD2_k127_6831555_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 450.0
HFD2_k127_6831555_1 AAA ATPase domain K05847 - - 0.00000000000000000000844 98.0
HFD2_k127_6924564_0 AIR synthase related protein, N-terminal domain K01933,K11788 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 374.0
HFD2_k127_6924564_1 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 365.0
HFD2_k127_6924564_2 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 350.0
HFD2_k127_6924564_3 LssY C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 310.0
HFD2_k127_6924564_4 Trypsin-like serine protease K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003429 290.0
HFD2_k127_6924564_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000001656 238.0
HFD2_k127_6924564_6 ABC-type nitrate sulfonate bicarbonate transport system, periplasmic component K02051 - - 0.0000000000000000000000000000000000000000000009801 183.0
HFD2_k127_6924564_7 Belongs to the ompA family K03640 - - 0.000000000000000000000000000002308 133.0
HFD2_k127_6997127_0 PFAM transposase, IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003585 291.0
HFD2_k127_6997127_1 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006459 275.0
HFD2_k127_6997127_2 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.00000000000000000004218 91.0
HFD2_k127_7017166_0 helicase K08282 - 2.7.11.1 1.094e-314 987.0
HFD2_k127_7017166_1 Flavin-binding monooxygenase-like K03379,K21730 - 1.14.13.160,1.14.13.22 1.652e-262 822.0
HFD2_k127_7017166_2 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002553 287.0
HFD2_k127_7017166_3 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006807 286.0
HFD2_k127_7017166_4 Zinc finger SWIM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000003907 249.0
HFD2_k127_7017166_5 Oxidoreductase family, C-terminal alpha/beta domain K19181 - 1.1.1.292 0.000000000000000000000000000000000000000000003224 177.0
HFD2_k127_7017166_6 PFAM Cupin 2, conserved barrel - - - 0.00000000000000000000000000001192 121.0
HFD2_k127_7017166_7 Pectate lyase - - - 0.0000000000000000000000000002879 132.0
HFD2_k127_7017166_8 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000002489 117.0
HFD2_k127_7017166_9 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000006137 79.0
HFD2_k127_7033933_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 2.806e-263 830.0
HFD2_k127_7033933_1 4Fe-4S dicluster domain K00184 - - 1.416e-204 671.0
HFD2_k127_7033933_10 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 433.0
HFD2_k127_7033933_11 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 428.0
HFD2_k127_7033933_12 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 404.0
HFD2_k127_7033933_13 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 391.0
HFD2_k127_7033933_14 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 353.0
HFD2_k127_7033933_15 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 337.0
HFD2_k127_7033933_16 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 336.0
HFD2_k127_7033933_17 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 293.0
HFD2_k127_7033933_18 Phage integrase, N-terminal SAM-like domain K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001411 264.0
HFD2_k127_7033933_19 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002404 252.0
HFD2_k127_7033933_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 613.0
HFD2_k127_7033933_20 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000004501 263.0
HFD2_k127_7033933_21 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000006506 234.0
HFD2_k127_7033933_22 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000006986 226.0
HFD2_k127_7033933_23 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000001016 218.0
HFD2_k127_7033933_24 Pfam Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000001003 192.0
HFD2_k127_7033933_25 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000004996 183.0
HFD2_k127_7033933_26 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000002065 158.0
HFD2_k127_7033933_27 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000001391 156.0
HFD2_k127_7033933_28 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000009618 139.0
HFD2_k127_7033933_29 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.0000000000000000000000000000001697 131.0
HFD2_k127_7033933_3 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 605.0
HFD2_k127_7033933_30 Belongs to the ComB family K05979 - 3.1.3.71 0.00000000000000000000000001606 120.0
HFD2_k127_7033933_31 Transcriptional regulator - - - 0.0000000000000000000000003084 117.0
HFD2_k127_7033933_32 ThiS family K03636 - - 0.0000000000000000000004617 100.0
HFD2_k127_7033933_33 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000005978 112.0
HFD2_k127_7033933_34 cytochrome c - - - 0.000000000000000000002009 101.0
HFD2_k127_7033933_35 - - - - 0.000004839 50.0
HFD2_k127_7033933_4 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 563.0
HFD2_k127_7033933_5 Belongs to the ALAD family K01698 GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 503.0
HFD2_k127_7033933_6 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 507.0
HFD2_k127_7033933_7 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 460.0
HFD2_k127_7033933_8 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 463.0
HFD2_k127_7033933_9 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 440.0
HFD2_k127_7034040_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 9.944e-295 913.0
HFD2_k127_7034040_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 8.489e-251 808.0
HFD2_k127_7034040_10 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000001367 200.0
HFD2_k127_7034040_11 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0030312,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000005268 187.0
HFD2_k127_7034040_12 Haem-binding domain - - - 0.000000000000000000000000000000000000000000000001382 179.0
HFD2_k127_7034040_13 Aminoacyl-tRNA editing domain K19055 - - 0.00000000000000000000000000001395 124.0
HFD2_k127_7034040_14 IMP dehydrogenase activity K04767 - - 0.0000000000000000000000119 108.0
HFD2_k127_7034040_15 Domain in cystathionine beta-synthase and other proteins. K04767 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - 0.00000000000000000004278 98.0
HFD2_k127_7034040_16 Phosphopantetheine attachment site - - - 0.000000000000003732 88.0
HFD2_k127_7034040_17 malic enzyme K00027,K00029 - 1.1.1.38,1.1.1.40 0.000000000000006507 87.0
HFD2_k127_7034040_18 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000002703 70.0
HFD2_k127_7034040_19 THUMP domain K06963 - - 0.00000000053 72.0
HFD2_k127_7034040_2 S-acyltransferase activity K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 463.0
HFD2_k127_7034040_20 Uncharacterized conserved protein (DUF2267) - - - 0.0001724 51.0
HFD2_k127_7034040_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162,K11381 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 468.0
HFD2_k127_7034040_4 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 451.0
HFD2_k127_7034040_5 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K00162,K11381,K21416 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 436.0
HFD2_k127_7034040_6 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 347.0
HFD2_k127_7034040_7 Predicted membrane protein (DUF2238) K08984 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005232 273.0
HFD2_k127_7034040_8 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000003959 216.0
HFD2_k127_7034040_9 Membrane K08984 - - 0.00000000000000000000000000000000000000000000000000000000007912 211.0
HFD2_k127_7037645_0 COG1228 Imidazolonepropionase and related amidohydrolases - - - 7.795e-198 623.0
HFD2_k127_7037645_1 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 - 3.5.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 299.0
HFD2_k127_7037645_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005507 250.0
HFD2_k127_7037645_3 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000004153 235.0
HFD2_k127_7037645_4 Helix-hairpin-helix motif - - - 0.0000000000000000000003369 101.0
HFD2_k127_7037645_5 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000001182 85.0
HFD2_k127_7037645_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000104 76.0
HFD2_k127_7037645_7 AAA ATPase forming ring-shaped complexes K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - 0.0000000000006593 71.0
HFD2_k127_7075616_0 High confidence in function and specificity - - - 4.857e-273 860.0
HFD2_k127_7075616_1 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 3.169e-268 847.0
HFD2_k127_7075616_10 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 409.0
HFD2_k127_7075616_11 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 400.0
HFD2_k127_7075616_12 acetyl-coa acetyltransferase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 396.0
HFD2_k127_7075616_13 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 385.0
HFD2_k127_7075616_14 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 342.0
HFD2_k127_7075616_15 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006025 328.0
HFD2_k127_7075616_16 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 321.0
HFD2_k127_7075616_17 PFAM Metallophosphoesterase K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 312.0
HFD2_k127_7075616_18 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008652 273.0
HFD2_k127_7075616_19 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001614 270.0
HFD2_k127_7075616_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 8.48e-216 685.0
HFD2_k127_7075616_20 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000006442 205.0
HFD2_k127_7075616_21 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000005818 205.0
HFD2_k127_7075616_22 - - - - 0.0000000000000000000000000000000000000000000000004924 181.0
HFD2_k127_7075616_23 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000974 192.0
HFD2_k127_7075616_24 intermembrane phospholipid transfer K07323 - - 0.0000000000000000000000000000000000001013 152.0
HFD2_k127_7075616_25 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000000000000299 146.0
HFD2_k127_7075616_26 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000003102 143.0
HFD2_k127_7075616_27 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000005529 132.0
HFD2_k127_7075616_28 Dienelactone hydrolase - - - 0.0000000000000000000000001563 120.0
HFD2_k127_7075616_29 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000001637 115.0
HFD2_k127_7075616_3 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 1.566e-208 675.0
HFD2_k127_7075616_30 ATPase activity K16922 - - 0.000000000000000000001085 110.0
HFD2_k127_7075616_31 helix_turn_helix, cAMP Regulatory protein K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00000000000000000002378 96.0
HFD2_k127_7075616_32 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000006214 101.0
HFD2_k127_7075616_33 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000003941 74.0
HFD2_k127_7075616_34 Cbs domain K04767 - - 0.0000000000003201 75.0
HFD2_k127_7075616_35 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000008255 72.0
HFD2_k127_7075616_36 - - - - 0.000000000003589 78.0
HFD2_k127_7075616_37 energy transducer activity K03832 - - 0.0000000009287 70.0
HFD2_k127_7075616_38 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000001302 63.0
HFD2_k127_7075616_39 - - - - 0.0000002532 59.0
HFD2_k127_7075616_4 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 562.0
HFD2_k127_7075616_42 cell cycle K05589,K13052 - - 0.0001912 50.0
HFD2_k127_7075616_43 Cellulose synthase K00694 - 2.4.1.12 0.0007708 52.0
HFD2_k127_7075616_5 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 518.0
HFD2_k127_7075616_6 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 535.0
HFD2_k127_7075616_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 491.0
HFD2_k127_7075616_8 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 466.0
HFD2_k127_7075616_9 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 469.0
HFD2_k127_7130153_0 Transport of potassium into the cell K03549 - - 1.163e-213 683.0
HFD2_k127_7130153_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 616.0
HFD2_k127_7130153_10 Receptor family ligand binding region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 342.0
HFD2_k127_7130153_11 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 323.0
HFD2_k127_7130153_12 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 346.0
HFD2_k127_7130153_13 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 306.0
HFD2_k127_7130153_14 ABC-type dipeptide oligopeptide nickel transport systems, permease components K15585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 305.0
HFD2_k127_7130153_15 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008808 308.0
HFD2_k127_7130153_16 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002745 290.0
HFD2_k127_7130153_17 Zn-dependent hydrolases of the beta-lactamase fold K13985 - 3.1.4.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000001204 274.0
HFD2_k127_7130153_18 Cell division protein ZipA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001272 262.0
HFD2_k127_7130153_19 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002658 267.0
HFD2_k127_7130153_2 Receptor family ligand binding region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 470.0
HFD2_k127_7130153_20 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003525 257.0
HFD2_k127_7130153_21 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001715 259.0
HFD2_k127_7130153_22 COG4177 ABC-type branched-chain amino acid transport system, permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001241 272.0
HFD2_k127_7130153_23 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000003645 241.0
HFD2_k127_7130153_24 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000002443 235.0
HFD2_k127_7130153_25 PFAM Peptidase M16 inactive domain - - - 0.0000000000000000000000000000000000000000000000000000000001562 231.0
HFD2_k127_7130153_26 Belongs to the helicase family. UvrD subfamily - - - 0.0000000000000000000000000000000000000000000000000000000003414 214.0
HFD2_k127_7130153_27 KR domain - - - 0.000000000000000000000000000000000000000000000005022 195.0
HFD2_k127_7130153_28 HAD-hyrolase-like K07025 - - 0.000000000000000000000000000000000000000001898 176.0
HFD2_k127_7130153_29 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000001203 154.0
HFD2_k127_7130153_3 MlrC C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 419.0
HFD2_k127_7130153_30 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000008956 143.0
HFD2_k127_7130153_31 Protein of unknown function (DUF1054) - - - 0.0000000000000000000000000000000000006858 149.0
HFD2_k127_7130153_32 Thiopurine S-methyltransferase K00569 - 2.1.1.67 0.000000000000000000000000000000000001868 154.0
HFD2_k127_7130153_33 Protein of unknown function (DUF3047) - - - 0.00000000000000000000000000143 122.0
HFD2_k127_7130153_34 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000008555 115.0
HFD2_k127_7130153_35 Tautomerase enzyme K01821 - 5.3.2.6 0.00000000000000004641 85.0
HFD2_k127_7130153_36 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000009702 70.0
HFD2_k127_7130153_4 AMP-binding enzyme C-terminal domain K16876 - 6.2.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 415.0
HFD2_k127_7130153_5 transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 389.0
HFD2_k127_7130153_6 gluconolactonase K01053,K14274 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 362.0
HFD2_k127_7130153_7 Phospholipase D Transphosphatidylase K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 368.0
HFD2_k127_7130153_8 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 348.0
HFD2_k127_7130153_9 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 354.0
HFD2_k127_7152160_0 Xanthine dehydrogenase K03520 - 1.2.5.3 2.075e-280 884.0
HFD2_k127_7152160_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 523.0
HFD2_k127_7152160_10 PFAM Cyclic nucleotide-binding K10914,K21564 - - 0.000000000000000000000000000000001019 151.0
HFD2_k127_7152160_11 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000000000004107 133.0
HFD2_k127_7152160_12 FAD binding domain - - - 0.00000000000000000000000000000007914 140.0
HFD2_k127_7152160_13 PFAM CBS domain K04767 - - 0.000000000000000000000000000002666 134.0
HFD2_k127_7152160_14 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000000006292 107.0
HFD2_k127_7152160_15 Pfam:DUF59 - - - 0.000000000000000000007237 107.0
HFD2_k127_7152160_16 Universal stress protein family - - - 0.0000000000000000001145 95.0
HFD2_k127_7152160_17 cyclic nucleotide-binding - - - 0.0000000000000003375 84.0
HFD2_k127_7152160_18 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K10676 - 1.14.13.20 0.000000000000001257 86.0
HFD2_k127_7152160_19 Cbs domain K04767 - - 0.0006341 44.0
HFD2_k127_7152160_2 Fe-S oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 371.0
HFD2_k127_7152160_20 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.0006811 46.0
HFD2_k127_7152160_3 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009348 352.0
HFD2_k127_7152160_4 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 297.0
HFD2_k127_7152160_5 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000003539 296.0
HFD2_k127_7152160_6 Belongs to the heme-copper respiratory oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001169 264.0
HFD2_k127_7152160_7 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000002911 215.0
HFD2_k127_7152160_8 Domain of unknown function (DUF1858) - - - 0.000000000000000000000000000000000000000000004198 177.0
HFD2_k127_7152160_9 COG3005 Nitrate TMAO K15876 - - 0.000000000000000000000000000000000000000001003 160.0
HFD2_k127_7166825_0 FAD dependent oxidoreductase - - - 2.372e-200 633.0
HFD2_k127_7166825_1 N-terminal domain of (some) glycogen debranching enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 600.0
HFD2_k127_7166825_10 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 305.0
HFD2_k127_7166825_11 fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 294.0
HFD2_k127_7166825_12 Nucleotidyl transferase of unknown function (DUF2204) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009539 312.0
HFD2_k127_7166825_13 Pfam:UPF0118 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 301.0
HFD2_k127_7166825_14 Ribonuclease, BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000005512 217.0
HFD2_k127_7166825_15 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000006635 149.0
HFD2_k127_7166825_16 Sigma-70, region 4 K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000002015 136.0
HFD2_k127_7166825_17 Fibronectin type 3 domain - - - 0.00000000000000000000000000000002591 146.0
HFD2_k127_7166825_18 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000002739 132.0
HFD2_k127_7166825_19 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000002464 135.0
HFD2_k127_7166825_2 argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 522.0
HFD2_k127_7166825_20 O-antigen ligase like membrane protein - - - 0.000000000000000000000006795 115.0
HFD2_k127_7166825_21 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000001725 102.0
HFD2_k127_7166825_22 - - - - 0.0000000000000000003247 98.0
HFD2_k127_7166825_23 PFAM phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.000000000000000003512 94.0
HFD2_k127_7166825_24 Protein of unknown function (DUF3309) - - - 0.00000000000000001593 83.0
HFD2_k127_7166825_25 - - - - 0.0000000000000007673 84.0
HFD2_k127_7166825_26 Diacylglycerol kinase - - - 0.00000000004444 74.0
HFD2_k127_7166825_27 - - - - 0.00000000005694 68.0
HFD2_k127_7166825_28 Periplasmic or secreted lipoprotein K04065 - - 0.00000000131 66.0
HFD2_k127_7166825_29 - - - - 0.0000007423 60.0
HFD2_k127_7166825_3 Bacterial sugar transferase K03606,K20997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 492.0
HFD2_k127_7166825_30 Lysylphosphatidylglycerol synthase TM region - - - 0.0008495 51.0
HFD2_k127_7166825_4 Polysaccharide pyruvyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 466.0
HFD2_k127_7166825_5 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 432.0
HFD2_k127_7166825_6 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008595 406.0
HFD2_k127_7166825_7 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 398.0
HFD2_k127_7166825_8 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 364.0
HFD2_k127_7166825_9 metallophosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 331.0
HFD2_k127_7182709_0 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 8.325e-306 968.0
HFD2_k127_7182709_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 427.0
HFD2_k127_7182709_10 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000001549 209.0
HFD2_k127_7182709_11 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.0000000000000000000386 104.0
HFD2_k127_7182709_12 carboxylic ester hydrolase activity - - - 0.000000000000000004832 96.0
HFD2_k127_7182709_13 Sugar (and other) transporter - - - 0.0000006288 62.0
HFD2_k127_7182709_2 Bacterial extracellular solute-binding proteins, family 5 Middle K13893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 428.0
HFD2_k127_7182709_3 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 412.0
HFD2_k127_7182709_4 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 395.0
HFD2_k127_7182709_5 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 374.0
HFD2_k127_7182709_6 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 385.0
HFD2_k127_7182709_7 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008927 271.0
HFD2_k127_7182709_8 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000145 281.0
HFD2_k127_7182709_9 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000005887 237.0
HFD2_k127_7191681_0 FAD dependent oxidoreductase - - - 0.0 1024.0
HFD2_k127_7191681_1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009889 474.0
HFD2_k127_7191681_10 Glycine/sarcosine/betaine reductase component B subunits - - - 0.000000000000000000000000000000000000000000000000000000000000068 229.0
HFD2_k127_7191681_11 PFAM Glycine sarcosine betaine reductase complex, protein B, alpha and beta subunits K10671 - 1.21.4.2 0.000000000000000000000000000000000000000000000000000000001571 217.0
HFD2_k127_7191681_12 Protein of unknown function (DUF2459) - - - 0.000000000000000000000000000000000008768 142.0
HFD2_k127_7191681_13 Selenoprotein B, glycine betaine sarcosine D-proline reductase family K10672 - 1.21.4.2 0.000000000000000000000003718 104.0
HFD2_k127_7191681_14 Glycine reductase complex selenoprotein A K10670 - 1.21.4.2,1.21.4.3,1.21.4.4 0.00000000000000000000002184 102.0
HFD2_k127_7191681_15 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10672 - 1.21.4.2 0.00000000000000000001075 94.0
HFD2_k127_7191681_16 Glycine reductase complex selenoprotein A K10670 - 1.21.4.2,1.21.4.3,1.21.4.4 0.000000005667 58.0
HFD2_k127_7191681_17 Protein of unknown function (DUF3494) - - - 0.00000001227 70.0
HFD2_k127_7191681_18 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.00000005729 62.0
HFD2_k127_7191681_2 Aminotransferase K11358 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 441.0
HFD2_k127_7191681_3 Selenoprotein B, glycine betaine sarcosine D-proline reductase family K10672 - 1.21.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008422 353.0
HFD2_k127_7191681_4 zinc ion binding K07048 GO:0008150,GO:0009888,GO:0009987,GO:0030154,GO:0030855,GO:0032502,GO:0048856,GO:0048869,GO:0060429 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 307.0
HFD2_k127_7191681_5 Selenoprotein B, glycine betaine sarcosine D-proline reductase family K10672 - 1.21.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 302.0
HFD2_k127_7191681_6 PFAM Archaeal ATPase K06921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 302.0
HFD2_k127_7191681_7 YD repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 323.0
HFD2_k127_7191681_8 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006321 286.0
HFD2_k127_7191681_9 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003484 245.0
HFD2_k127_7228335_0 PFAM ATP-binding region K02484,K07678 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 420.0
HFD2_k127_7228335_1 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 426.0
HFD2_k127_7228335_10 Seven times multi-haem cytochrome CxxCH K10535 - 1.7.2.6 0.000000000000000000000000000000000000000000000000000002387 212.0
HFD2_k127_7228335_11 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000001232 168.0
HFD2_k127_7228335_12 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000002562 138.0
HFD2_k127_7228335_13 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000004504 135.0
HFD2_k127_7228335_14 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.000000000000000000000000000115 132.0
HFD2_k127_7228335_15 Protein of unknown function (DUF1810) - - - 0.000000000000000000000000007697 114.0
HFD2_k127_7228335_16 - - - - 0.0000000000000000000000123 106.0
HFD2_k127_7228335_17 YceI-like domain - - - 0.0000000000000009716 85.0
HFD2_k127_7228335_19 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000008982 75.0
HFD2_k127_7228335_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 422.0
HFD2_k127_7228335_20 Sugar ABC transporter permease K15771 - - 0.0000000179 59.0
HFD2_k127_7228335_21 mechanosensitive ion channel K03442,K16052 - - 0.00000008617 57.0
HFD2_k127_7228335_22 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000873 65.0
HFD2_k127_7228335_23 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.00002511 55.0
HFD2_k127_7228335_24 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0001811 55.0
HFD2_k127_7228335_3 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 322.0
HFD2_k127_7228335_4 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 334.0
HFD2_k127_7228335_5 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 314.0
HFD2_k127_7228335_6 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 308.0
HFD2_k127_7228335_7 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008919 278.0
HFD2_k127_7228335_8 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005384 247.0
HFD2_k127_7228335_9 Protein of unknown function (DUF1345) - - - 0.00000000000000000000000000000000000000000000000000000000000001875 222.0
HFD2_k127_7248276_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 7.835e-264 823.0
HFD2_k127_7248276_1 Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 406.0
HFD2_k127_7248276_10 - - - - 0.0000048 58.0
HFD2_k127_7248276_2 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006851 388.0
HFD2_k127_7248276_3 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 387.0
HFD2_k127_7248276_4 aldo-keto reductase (NADP) activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 357.0
HFD2_k127_7248276_5 glucose sorbosone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 359.0
HFD2_k127_7248276_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 343.0
HFD2_k127_7248276_7 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000001628 200.0
HFD2_k127_7248276_8 Protein of unknown function (DUF1566) - - - 0.00000000000000000000000000000000000000000649 175.0
HFD2_k127_7248276_9 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000003567 144.0
HFD2_k127_7262220_0 - - - - 0.00000000000000000000000000000000000000000000000000000001409 220.0
HFD2_k127_7262220_1 Domain of unknown function (DUF4442) - - - 0.0004645 53.0
HFD2_k127_7282127_0 B12 binding domain K00548 - 2.1.1.13 0.0 1425.0
HFD2_k127_7282127_1 Protein of unknown function, DUF255 K06888 - - 1.946e-241 778.0
HFD2_k127_7282127_10 Transketolase, central region K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 304.0
HFD2_k127_7282127_11 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 293.0
HFD2_k127_7282127_12 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000305 282.0
HFD2_k127_7282127_13 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001947 280.0
HFD2_k127_7282127_14 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000001094 273.0
HFD2_k127_7282127_15 ABC transporter substrate-binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009798 267.0
HFD2_k127_7282127_16 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009695 256.0
HFD2_k127_7282127_17 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000001887 259.0
HFD2_k127_7282127_18 FES K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002243 263.0
HFD2_k127_7282127_19 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.0000000000000000000000000000000000000000000000000000000000000000007802 236.0
HFD2_k127_7282127_2 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 604.0
HFD2_k127_7282127_20 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000002798 244.0
HFD2_k127_7282127_21 racemase activity, acting on amino acids and derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000005195 246.0
HFD2_k127_7282127_22 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000126 230.0
HFD2_k127_7282127_23 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000002228 228.0
HFD2_k127_7282127_24 domain protein K01992,K06994 - - 0.000000000000000000000000000000000000000000000000000000000000009928 228.0
HFD2_k127_7282127_25 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000000001415 213.0
HFD2_k127_7282127_26 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000004813 219.0
HFD2_k127_7282127_27 Thioesterase K07107 - - 0.0000000000000000000000000000000000000000000000000000004147 205.0
HFD2_k127_7282127_28 CDP-diacylglycerol pyrophosphatase K01521 - 3.6.1.26 0.00000000000000000000000000000000000000000000000003415 190.0
HFD2_k127_7282127_29 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000101 177.0
HFD2_k127_7282127_3 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 566.0
HFD2_k127_7282127_30 cytokinin biosynthetic process K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000001402 177.0
HFD2_k127_7282127_31 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000003775 177.0
HFD2_k127_7282127_32 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000001588 188.0
HFD2_k127_7282127_33 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000001796 184.0
HFD2_k127_7282127_35 - - - - 0.00000000000000000000000000000000000003488 148.0
HFD2_k127_7282127_36 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.000000000000000000000000000000000001148 150.0
HFD2_k127_7282127_37 Predicted membrane protein (DUF2079) - - - 0.00000000000000000000000000000007719 144.0
HFD2_k127_7282127_38 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000282 125.0
HFD2_k127_7282127_39 Nitroreductase family - - - 0.0000000000000000000001271 104.0
HFD2_k127_7282127_4 Putative modulator of DNA gyrase K03592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 462.0
HFD2_k127_7282127_40 DinB superfamily - - - 0.000000000000000009705 96.0
HFD2_k127_7282127_41 COG2104 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.000000000000614 72.0
HFD2_k127_7282127_42 - - - - 0.000000009525 68.0
HFD2_k127_7282127_43 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000001591 64.0
HFD2_k127_7282127_5 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 370.0
HFD2_k127_7282127_6 NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 341.0
HFD2_k127_7282127_7 Peptidase family M28 K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009959 343.0
HFD2_k127_7282127_8 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 331.0
HFD2_k127_7282127_9 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 341.0
HFD2_k127_7322350_0 MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 394.0
HFD2_k127_7322350_1 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000439 154.0
HFD2_k127_7322350_2 - - - - 0.0000000000000001211 81.0
HFD2_k127_7434787_0 Belongs to the transketolase family K00163 - 1.2.4.1 7.718e-233 745.0
HFD2_k127_7434787_1 Belongs to the IlvD Edd family - - - 2.861e-224 709.0
HFD2_k127_7434787_10 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000007251 233.0
HFD2_k127_7434787_11 anaphase-promoting complex-dependent catabolic process - - - 0.0000000000000000000000000000000000000000000000009624 181.0
HFD2_k127_7434787_13 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation K13570 GO:0003674,GO:0005488,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0031386,GO:0032446,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044877,GO:0051603,GO:0070490,GO:0070628,GO:0070647,GO:0071704,GO:1901564,GO:1901565,GO:1901575 - 0.0000000351 58.0
HFD2_k127_7434787_14 Glycine D-amino acid K00285 - 1.4.5.1 0.0002263 49.0
HFD2_k127_7434787_2 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 499.0
HFD2_k127_7434787_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00529 - 1.18.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 411.0
HFD2_k127_7434787_4 COG0463 Glycosyltransferases involved in cell wall biogenesis K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 410.0
HFD2_k127_7434787_5 Fungal family of unknown function (DUF1776) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 391.0
HFD2_k127_7434787_6 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000003746 281.0
HFD2_k127_7434787_7 CoA-transferase family III K18702 - 2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000006011 273.0
HFD2_k127_7434787_8 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003259 261.0
HFD2_k127_7434787_9 ThiJ PfpI - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009806 255.0
HFD2_k127_7481469_0 Putative esterase - - - 0.00000000000000000000000000000000000000000000000002216 196.0
HFD2_k127_7481469_1 Protein of unknown function (DUF692) K09930 - - 0.000004706 51.0
HFD2_k127_7489279_0 Glycosyltransferase family 20 K00697,K13057,K20436 - 2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135 2.2e-241 777.0
HFD2_k127_7489279_1 UDP-N-acetylmuramate-L-alanine ligase activity K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 552.0
HFD2_k127_7489279_10 Aminotransferase class-V - GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 435.0
HFD2_k127_7489279_11 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 443.0
HFD2_k127_7489279_12 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 409.0
HFD2_k127_7489279_13 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008003 419.0
HFD2_k127_7489279_14 Histidyl-tRNA synthetase K00765,K01892,K02502 - 2.4.2.17,6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 386.0
HFD2_k127_7489279_15 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 375.0
HFD2_k127_7489279_16 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 363.0
HFD2_k127_7489279_17 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000907 376.0
HFD2_k127_7489279_18 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 338.0
HFD2_k127_7489279_19 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 306.0
HFD2_k127_7489279_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 526.0
HFD2_k127_7489279_20 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 334.0
HFD2_k127_7489279_21 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 291.0
HFD2_k127_7489279_22 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000005475 263.0
HFD2_k127_7489279_23 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000003686 227.0
HFD2_k127_7489279_24 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000001424 219.0
HFD2_k127_7489279_25 Phosphoglycerate mutase family K22305 - 3.1.3.3 0.0000000000000000000000000000000000000000003529 165.0
HFD2_k127_7489279_26 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K00697,K01087,K16055 GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0033554,GO:0034637,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0046872,GO:0050896,GO:0051716,GO:0070413,GO:0070415,GO:0070417,GO:0071704,GO:1901576 2.4.1.15,2.4.1.347,3.1.3.12 0.000000000000000000000000000000000000001884 162.0
HFD2_k127_7489279_27 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000357 145.0
HFD2_k127_7489279_28 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000000001973 125.0
HFD2_k127_7489279_29 DivIVA protein K04074 - - 0.0000000000000000000001826 103.0
HFD2_k127_7489279_3 phosphorelay signal transduction system K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 524.0
HFD2_k127_7489279_30 Tim44 - - - 0.000000000000000000001998 104.0
HFD2_k127_7489279_31 YGGT family K02221 - - 0.0000000000000000000243 98.0
HFD2_k127_7489279_32 Cell division protein FtsQ K03589 - - 0.0000000000000000005369 103.0
HFD2_k127_7489279_33 DUF167 - - - 0.000000000000006051 78.0
HFD2_k127_7489279_34 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000009099 71.0
HFD2_k127_7489279_35 pilus assembly protein PilW K02672 - - 0.0000000001825 68.0
HFD2_k127_7489279_37 Cell division protein FtsL - - - 0.0002569 51.0
HFD2_k127_7489279_4 phosphorelay signal transduction system K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 522.0
HFD2_k127_7489279_5 Multi-sensor signal transduction histidine kinase K07710 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 527.0
HFD2_k127_7489279_6 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 497.0
HFD2_k127_7489279_7 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 502.0
HFD2_k127_7489279_8 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 461.0
HFD2_k127_7489279_9 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 441.0
HFD2_k127_74921_0 (ABC) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 454.0
HFD2_k127_74921_1 Universal stress protein - - - 0.000001976 58.0
HFD2_k127_7508450_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 416.0
HFD2_k127_7508450_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 405.0
HFD2_k127_7508450_2 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 304.0
HFD2_k127_7508450_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000619 306.0
HFD2_k127_7508450_4 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000559 263.0
HFD2_k127_7508450_5 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000001071 188.0
HFD2_k127_7508450_6 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000005068 184.0
HFD2_k127_7508450_7 diguanylate cyclase - - - 0.0000000000000000000000000000000000005859 153.0
HFD2_k127_7508450_8 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.0000000000000000000000000000000002158 148.0
HFD2_k127_7508450_9 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000001005 93.0
HFD2_k127_7509460_0 Belongs to the IlvD Edd family K22396 - 4.2.1.82 2.199e-313 971.0
HFD2_k127_7509460_1 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 565.0
HFD2_k127_7509460_2 AIR synthase related protein, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 543.0
HFD2_k127_7509460_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000005377 183.0
HFD2_k127_7601535_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 480.0
HFD2_k127_7601535_1 acyl-CoA dehydrogenase K00252 - 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 488.0
HFD2_k127_7601535_10 PFAM UBA THIF-type NAD FAD binding protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000006013 121.0
HFD2_k127_7601535_11 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.000000000000000000000000003157 119.0
HFD2_k127_7601535_12 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000001693 92.0
HFD2_k127_7601535_13 Protein conserved in bacteria K09986 - - 0.00000000001487 75.0
HFD2_k127_7601535_2 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 464.0
HFD2_k127_7601535_3 domain protein K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 339.0
HFD2_k127_7601535_4 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 310.0
HFD2_k127_7601535_5 Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 302.0
HFD2_k127_7601535_6 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000003827 255.0
HFD2_k127_7601535_7 serine-type endopeptidase activity K04691,K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000003142 212.0
HFD2_k127_7601535_8 dTDP-4-dehydrorhamnose 3,5-epimerase activity K01790 - 5.1.3.13 0.000000000000000000000000000000000000002044 165.0
HFD2_k127_7601535_9 Glycine-zipper domain - - - 0.0000000000000000000000000000002278 127.0
HFD2_k127_7602426_0 xanthine dehydrogenase activity K03520 - 1.2.5.3 9.91e-317 987.0
HFD2_k127_7602426_1 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 443.0
HFD2_k127_7602426_10 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 358.0
HFD2_k127_7602426_12 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 334.0
HFD2_k127_7602426_13 tRNA processing K06864,K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 317.0
HFD2_k127_7602426_14 xanthine dehydrogenase activity K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 314.0
HFD2_k127_7602426_15 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006791 328.0
HFD2_k127_7602426_16 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 315.0
HFD2_k127_7602426_17 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002828 274.0
HFD2_k127_7602426_18 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003237 288.0
HFD2_k127_7602426_19 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000013 231.0
HFD2_k127_7602426_2 COG0524 Sugar kinases, ribokinase family K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 415.0
HFD2_k127_7602426_20 'Molybdopterin - - - 0.0000000000000000000000000000000000000000000000000000000001471 224.0
HFD2_k127_7602426_21 serine-type endopeptidase activity K04691,K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000005649 192.0
HFD2_k127_7602426_22 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000002936 169.0
HFD2_k127_7602426_23 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.000000000000000000000000000000000000000001547 164.0
HFD2_k127_7602426_24 Molybdopterin converting factor, small subunit K03636 - - 0.00000000000000000000000000003885 119.0
HFD2_k127_7602426_25 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000002117 109.0
HFD2_k127_7602426_26 Virulence factor BrkB K07058 - - 0.000000000007044 76.0
HFD2_k127_7602426_27 Belongs to the 'phage' integrase family - - - 0.00000001337 64.0
HFD2_k127_7602426_28 Belongs to the 'phage' integrase family - - - 0.00003421 49.0
HFD2_k127_7602426_3 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 414.0
HFD2_k127_7602426_4 Associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 376.0
HFD2_k127_7602426_5 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 391.0
HFD2_k127_7602426_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 372.0
HFD2_k127_7602426_7 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 366.0
HFD2_k127_7602426_8 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 356.0
HFD2_k127_7602426_9 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 345.0
HFD2_k127_7620891_0 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000000003435 239.0
HFD2_k127_7620891_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000797 122.0
HFD2_k127_7620891_2 Mate efflux family protein - - - 0.000000000000000968 82.0
HFD2_k127_7738718_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 430.0
HFD2_k127_7738718_1 membrane organization - - - 0.000000000000000000000000000000000000000000000000000000000007727 213.0
HFD2_k127_7827244_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 448.0
HFD2_k127_7827244_1 IstB-like ATP binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002338 236.0
HFD2_k127_7892148_0 Short chain dehydrogenase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000002493 206.0
HFD2_k127_7892148_1 [2Fe-2S] binding domain K13483 - - 0.000000000000007923 86.0
HFD2_k127_7928467_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 444.0
HFD2_k127_7928467_1 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000929 362.0
HFD2_k127_7928467_2 intracellular protease amidase - - - 0.00000000000000000000000000000000000000000000000000000004472 213.0
HFD2_k127_7946398_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 2.23e-262 822.0
HFD2_k127_7946398_1 Radical SAM - - - 9.691e-212 668.0
HFD2_k127_7946398_10 Type II secretion system (T2SS), protein F K02455,K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 367.0
HFD2_k127_7946398_11 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 359.0
HFD2_k127_7946398_12 amino acid K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 342.0
HFD2_k127_7946398_13 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 340.0
HFD2_k127_7946398_14 KR domain K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 355.0
HFD2_k127_7946398_15 mannose-ethanolamine phosphotransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 331.0
HFD2_k127_7946398_16 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 316.0
HFD2_k127_7946398_17 Psort location Cytoplasmic, score K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004535 271.0
HFD2_k127_7946398_18 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000005277 268.0
HFD2_k127_7946398_19 Belongs to the beta-ketoacyl-ACP synthases family K05551,K09458 - 2.3.1.179,2.3.1.235,2.3.1.260 0.0000000000000000000000000000000000000000000000000000000000000000000000000005903 278.0
HFD2_k127_7946398_2 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 620.0
HFD2_k127_7946398_20 Bacterial type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001064 281.0
HFD2_k127_7946398_21 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000003284 258.0
HFD2_k127_7946398_22 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000001109 250.0
HFD2_k127_7946398_23 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000001333 205.0
HFD2_k127_7946398_24 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 0.0000000000000000000000000000000000000000000000000006331 194.0
HFD2_k127_7946398_25 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000785 179.0
HFD2_k127_7946398_26 Type II secretion system (T2SS), protein G K02456 - - 0.000000000000000000000000000000000000000000004623 169.0
HFD2_k127_7946398_27 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000003918 170.0
HFD2_k127_7946398_28 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000009004 164.0
HFD2_k127_7946398_29 glycosyl transferase - - - 0.000000000000000000000000000000000000000009455 176.0
HFD2_k127_7946398_3 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 625.0
HFD2_k127_7946398_30 Chromate transporter K07240 - - 0.000000000000000000000000000000000000004479 160.0
HFD2_k127_7946398_31 PFAM Glycosyl transferase, family 39 - - - 0.000000000000000000000000000000000000005465 165.0
HFD2_k127_7946398_32 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000001374 143.0
HFD2_k127_7946398_33 Cupin 2, conserved barrel domain protein K00971,K01809,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000001835 136.0
HFD2_k127_7946398_34 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000002351 138.0
HFD2_k127_7946398_35 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458,K21789 - 2.3.1.179 0.000000000000000000000007672 114.0
HFD2_k127_7946398_36 - - - - 0.00000000000000000000003829 111.0
HFD2_k127_7946398_38 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000001219 111.0
HFD2_k127_7946398_39 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000000000000002948 113.0
HFD2_k127_7946398_4 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 544.0
HFD2_k127_7946398_40 COG3267 Type II secretory pathway, component ExeA - - - 0.0000000000000000001215 103.0
HFD2_k127_7946398_41 Phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000006072 93.0
HFD2_k127_7946398_42 Gram-negative-bacterium-type cell wall biogenesis - - - 0.00000000000000009031 89.0
HFD2_k127_7946398_43 response regulator - - - 0.00000000000001022 83.0
HFD2_k127_7946398_44 Fimbrial assembly protein (PilN) K02461 - - 0.00000000000006406 85.0
HFD2_k127_7946398_45 Prokaryotic N-terminal methylation motif K02456,K02457,K02458,K02459,K02655,K10926 - - 0.000000005542 65.0
HFD2_k127_7946398_46 Type II secretion system (T2SS), protein M subtype b K02462 - - 0.00000001015 64.0
HFD2_k127_7946398_47 Prokaryotic N-terminal methylation motif K02458 - - 0.0000006392 61.0
HFD2_k127_7946398_48 Phosphopantetheine attachment site K02078 - - 0.000007168 58.0
HFD2_k127_7946398_49 general secretion pathway protein K02457 - - 0.0000258 55.0
HFD2_k127_7946398_5 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007229 496.0
HFD2_k127_7946398_50 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.00005748 53.0
HFD2_k127_7946398_51 - - - - 0.00008549 55.0
HFD2_k127_7946398_6 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 394.0
HFD2_k127_7946398_7 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 404.0
HFD2_k127_7946398_8 Belongs to the FGGY kinase family K00851 - 2.7.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 389.0
HFD2_k127_7946398_9 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006188 388.0
HFD2_k127_7951350_0 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 589.0
HFD2_k127_7951350_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 364.0
HFD2_k127_7951350_2 methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.0001368 47.0
HFD2_k127_7960646_0 Peptidase family M28 - - - 7.456e-209 664.0
HFD2_k127_7960646_1 peptidase S9B dipeptidylpeptidase IV domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 364.0
HFD2_k127_7960646_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000009291 92.0
HFD2_k127_7973817_0 OPT oligopeptide transporter protein - - - 4.835e-195 630.0
HFD2_k127_7973817_1 thiamine pyrophosphate binding K12261 GO:0001561,GO:0003674,GO:0003824,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015031,GO:0015833,GO:0016042,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0019395,GO:0019752,GO:0019842,GO:0022607,GO:0030258,GO:0030976,GO:0031907,GO:0031974,GO:0032787,GO:0033036,GO:0033365,GO:0034440,GO:0034613,GO:0036094,GO:0042579,GO:0042802,GO:0042886,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046907,GO:0048037,GO:0050662,GO:0051179,GO:0051234,GO:0051259,GO:0051641,GO:0051649,GO:0055114,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072329,GO:0072594,GO:0072662,GO:0072663,GO:0097159,GO:1901363,GO:1901575,GO:1901681 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 531.0
HFD2_k127_7973817_2 belongs to the bacterial solute-binding protein 3 family K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 512.0
HFD2_k127_7973817_3 polar amino acid transport system K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000711 443.0
HFD2_k127_7973817_4 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 383.0
HFD2_k127_7973817_5 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 372.0
HFD2_k127_7973817_6 Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate K07404 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 354.0
HFD2_k127_7973817_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000205 235.0
HFD2_k127_7973817_8 - - - - 0.000000000000000000000000000009934 127.0
HFD2_k127_7973817_9 - - - - 0.000000000000000000000001569 121.0
HFD2_k127_797857_0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain K01596,K01610 - 4.1.1.32,4.1.1.49 5.305e-226 709.0
HFD2_k127_797857_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 323.0
HFD2_k127_797857_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 305.0
HFD2_k127_797857_3 - - - - 0.0000000000000000000000000000000000000000000000008827 192.0
HFD2_k127_797857_4 Thioesterase superfamily - - - 0.0000000000009206 75.0
HFD2_k127_8001162_0 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 559.0
HFD2_k127_8001162_1 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005889 247.0
HFD2_k127_8001162_2 TIGRFAM SUF system FeS assembly protein, NifU family K04488 - - 0.0000000002242 73.0
HFD2_k127_8018814_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner - - - 5.134e-304 948.0
HFD2_k127_8018814_1 Gamma-glutamyltranspeptidase - - - 1.278e-203 651.0
HFD2_k127_8018814_10 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000003921 233.0
HFD2_k127_8018814_11 ABC-Type Dipeptide Transport System Periplasmic Component K02035,K13889 - - 0.00000000000000000000000000000000000000000000000000000000000000008295 245.0
HFD2_k127_8018814_12 dipeptide transport K02035 - - 0.000000000000000000000000000000000000000000000000000000000000001026 239.0
HFD2_k127_8018814_13 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000003078 199.0
HFD2_k127_8018814_14 belongs to the thioredoxin family K03671,K03672 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.8 0.00000000000000000000000000000000000000000000000000223 186.0
HFD2_k127_8018814_15 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000005157 209.0
HFD2_k127_8018814_16 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000006752 195.0
HFD2_k127_8018814_17 FG-GAP repeat protein - - - 0.000000000000000000000000000000000000000001998 177.0
HFD2_k127_8018814_18 Transcriptional regulator - - - 0.00000000000000000000000000000000000001341 154.0
HFD2_k127_8018814_2 xanthine dehydrogenase, a b hammerhead - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 535.0
HFD2_k127_8018814_3 Benzoate membrane transport protein K05782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 459.0
HFD2_k127_8018814_4 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 428.0
HFD2_k127_8018814_5 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 349.0
HFD2_k127_8018814_6 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 359.0
HFD2_k127_8018814_7 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 346.0
HFD2_k127_8018814_8 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 294.0
HFD2_k127_8018814_9 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001264 281.0
HFD2_k127_8020665_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 8.155e-276 867.0
HFD2_k127_8020665_1 DNA helicase K03654 - 3.6.4.12 6.497e-228 729.0
HFD2_k127_8020665_10 Fe-S type, tartrate fumarate subfamily, alpha subunit K03779 - 4.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 458.0
HFD2_k127_8020665_11 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 392.0
HFD2_k127_8020665_12 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 386.0
HFD2_k127_8020665_13 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 375.0
HFD2_k127_8020665_14 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 366.0
HFD2_k127_8020665_15 Belongs to the peptidase M48B family K03799 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 359.0
HFD2_k127_8020665_16 PFAM extracellular solute-binding protein family 1 K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 370.0
HFD2_k127_8020665_17 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 310.0
HFD2_k127_8020665_18 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 302.0
HFD2_k127_8020665_19 SMP-30 Gluconolaconase LRE domain protein K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001119 281.0
HFD2_k127_8020665_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 9.051e-214 675.0
HFD2_k127_8020665_20 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007168 259.0
HFD2_k127_8020665_21 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000218 261.0
HFD2_k127_8020665_22 3-oxoacyl-ACP reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000002064 267.0
HFD2_k127_8020665_23 COG1838 Tartrate dehydratase beta subunit Fumarate hydratase class I, C-terminal domain K03780 - 4.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000436 258.0
HFD2_k127_8020665_24 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.00000000000000000000000000000000000000000000000000000000000000000003101 238.0
HFD2_k127_8020665_25 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000005084 226.0
HFD2_k127_8020665_26 Thioredoxin-like K02199,K03671 - - 0.0000000000000000000000000000000000000000000000000000000008995 228.0
HFD2_k127_8020665_27 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000004605 198.0
HFD2_k127_8020665_28 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000005134 160.0
HFD2_k127_8020665_29 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.00000000000000000000000000000000000000008439 168.0
HFD2_k127_8020665_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.588e-212 681.0
HFD2_k127_8020665_30 HAD-superfamily hydrolase, subfamily IIB - - - 0.000000000000000000000000000000000002538 148.0
HFD2_k127_8020665_31 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000004132 141.0
HFD2_k127_8020665_32 hydroperoxide reductase activity - - - 0.00000000000000000000000000000007229 128.0
HFD2_k127_8020665_33 subunit of a heme lyase K02198,K02200 - - 0.00000000000000000000000000004269 122.0
HFD2_k127_8020665_34 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000002049 116.0
HFD2_k127_8020665_35 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000002584 119.0
HFD2_k127_8020665_36 COG0457 FOG TPR repeat - - - 0.000000000000000000000000002497 128.0
HFD2_k127_8020665_37 Cytidylate kinase-like family - - - 0.00000000000000000000000001417 121.0
HFD2_k127_8020665_38 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000004253 109.0
HFD2_k127_8020665_39 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000006691 110.0
HFD2_k127_8020665_4 Gamma-glutamyltranspeptidase - - - 6.498e-212 687.0
HFD2_k127_8020665_40 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000237 108.0
HFD2_k127_8020665_41 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000001378 106.0
HFD2_k127_8020665_42 Xylose isomerase-like TIM barrel K06606 - 5.3.99.11 0.000000000000000000004524 106.0
HFD2_k127_8020665_43 Ribosomal L32p protein family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000000003599 89.0
HFD2_k127_8020665_44 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000001468 83.0
HFD2_k127_8020665_45 Histidine kinase - - - 0.0000000000000007971 84.0
HFD2_k127_8020665_46 - - - - 0.000000000000005286 85.0
HFD2_k127_8020665_47 Protein of unknown function (DUF1706) - - - 0.00000000005601 73.0
HFD2_k127_8020665_48 Cupin domain - - - 0.000000002604 70.0
HFD2_k127_8020665_5 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009249 568.0
HFD2_k127_8020665_50 SMART Tetratricopeptide - - - 0.0003481 53.0
HFD2_k127_8020665_6 PFAM Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 570.0
HFD2_k127_8020665_7 PFAM Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 544.0
HFD2_k127_8020665_8 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009684 503.0
HFD2_k127_8020665_9 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 494.0
HFD2_k127_8029530_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1242.0
HFD2_k127_8029530_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 449.0
HFD2_k127_8029530_2 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 314.0
HFD2_k127_8041744_0 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006873 258.0
HFD2_k127_8041744_1 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000000000001425 117.0
HFD2_k127_8041744_2 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 0.0000000000000000001504 94.0
HFD2_k127_8041744_3 Iron-sulfur cluster assembly protein - - - 0.00000000000000000106 100.0
HFD2_k127_8041744_4 Transcriptional regulator - - - 0.000000000008322 71.0
HFD2_k127_8041744_5 Uncharacterized conserved protein (DUF2249) - - - 0.00000000001048 75.0
HFD2_k127_8042560_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000002599 224.0
HFD2_k127_8042560_1 DEAD/H associated K03724 - - 0.00000000000002307 75.0
HFD2_k127_8042560_2 helix_turn_helix, Lux Regulon - - - 0.0000000003726 66.0
HFD2_k127_8054977_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1092.0
HFD2_k127_8054977_1 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 8.958e-245 795.0
HFD2_k127_8054977_10 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 402.0
HFD2_k127_8054977_11 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 378.0
HFD2_k127_8054977_12 4 iron, 4 sulfur cluster binding K00113,K00176,K05524,K13795,K13796 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 382.0
HFD2_k127_8054977_13 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008012 372.0
HFD2_k127_8054977_14 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009249,GO:0009898,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 326.0
HFD2_k127_8054977_15 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 321.0
HFD2_k127_8054977_16 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 321.0
HFD2_k127_8054977_17 mandelate racemase muconate lactonizing K01856,K02549 - 4.2.1.113,5.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 317.0
HFD2_k127_8054977_18 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 318.0
HFD2_k127_8054977_19 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 308.0
HFD2_k127_8054977_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 9.367e-194 621.0
HFD2_k127_8054977_20 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 305.0
HFD2_k127_8054977_21 Phosphoenolpyruvate phosphomutase K20454 - 4.1.3.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 295.0
HFD2_k127_8054977_22 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 297.0
HFD2_k127_8054977_23 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004478 279.0
HFD2_k127_8054977_24 Uncharacterised MFS-type transporter YbfB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001584 260.0
HFD2_k127_8054977_25 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000005638 254.0
HFD2_k127_8054977_26 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000499 239.0
HFD2_k127_8054977_27 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000001076 232.0
HFD2_k127_8054977_28 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000003456 220.0
HFD2_k127_8054977_29 dihydroorotate dehydrogenase activity K02823,K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000003013 219.0
HFD2_k127_8054977_3 acetyl-coa acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 564.0
HFD2_k127_8054977_30 PFAM Short-chain dehydrogenase reductase SDR K00059,K03793 - 1.1.1.100,1.5.1.33 0.00000000000000000000000000000000000000000000000000000001827 207.0
HFD2_k127_8054977_31 MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000005437 194.0
HFD2_k127_8054977_32 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000006766 198.0
HFD2_k127_8054977_33 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000000000000002715 181.0
HFD2_k127_8054977_34 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000001464 181.0
HFD2_k127_8054977_35 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000009578 162.0
HFD2_k127_8054977_36 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000001365 165.0
HFD2_k127_8054977_37 hydrolase of the alpha beta superfamily K07018 - - 0.00000000000000000000000000000000000000002621 160.0
HFD2_k127_8054977_38 DNA helicase - - - 0.000000000000000000000000000000000000000176 164.0
HFD2_k127_8054977_39 Protein of unknown function (DUF2892) - - - 0.00000000000000000000000000000000000004226 150.0
HFD2_k127_8054977_4 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 527.0
HFD2_k127_8054977_40 - - - - 0.0000000000000000000000000000000000002222 150.0
HFD2_k127_8054977_41 Alkylmercury lyase - - - 0.0000000000000000000000000000000000009373 146.0
HFD2_k127_8054977_42 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.0000000000000000000000000000000000519 138.0
HFD2_k127_8054977_43 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000006355 150.0
HFD2_k127_8054977_44 - - - - 0.00000000000000000000000000000005347 129.0
HFD2_k127_8054977_45 belongs to the Fur family K03711,K09825 - - 0.0000000000000000000000000001383 121.0
HFD2_k127_8054977_46 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000009488 129.0
HFD2_k127_8054977_47 - - - - 0.000000000000000000005315 106.0
HFD2_k127_8054977_48 cyclic nucleotide-binding - - - 0.00000000000000000003702 99.0
HFD2_k127_8054977_49 Outer membrane lipoprotein - - - 0.000000000000000001965 98.0
HFD2_k127_8054977_5 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 503.0
HFD2_k127_8054977_50 - - - - 0.000000000000000002811 98.0
HFD2_k127_8054977_51 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000001601 78.0
HFD2_k127_8054977_52 Protein of unknown function (DUF3047) - - - 0.000000000002341 80.0
HFD2_k127_8054977_53 DNA methylase K00571,K00590 - 2.1.1.113,2.1.1.72 0.000000000002905 79.0
HFD2_k127_8054977_54 Tautomerase enzyme - - - 0.000000007128 69.0
HFD2_k127_8054977_55 COG3666 Transposase and inactivated derivatives - - - 0.0000008834 50.0
HFD2_k127_8054977_56 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.000001671 60.0
HFD2_k127_8054977_58 Mandelate Racemase Muconate Lactonizing - - - 0.0003158 49.0
HFD2_k127_8054977_59 AntiSigma factor - - - 0.0004452 51.0
HFD2_k127_8054977_6 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 501.0
HFD2_k127_8054977_60 - - - - 0.0009213 51.0
HFD2_k127_8054977_7 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 486.0
HFD2_k127_8054977_8 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 477.0
HFD2_k127_8054977_9 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 390.0
HFD2_k127_8059007_0 Putative glycosyl hydrolase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 344.0
HFD2_k127_8059007_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000002167 85.0
HFD2_k127_8059007_2 ACT domain - - - 0.000000004215 63.0
HFD2_k127_8059007_3 (ABC) transporter - - - 0.0000002378 55.0
HFD2_k127_8059007_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000109 53.0
HFD2_k127_8059390_0 esterase - - - 1.03e-214 689.0
HFD2_k127_8059390_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001437 247.0
HFD2_k127_8069236_0 lipopolysaccharide transport K22110 - - 0.0 1172.0
HFD2_k127_8069236_1 Belongs to the GPI family K01810 - 5.3.1.9 3.131e-273 869.0
HFD2_k127_8069236_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.781e-209 661.0
HFD2_k127_8069236_3 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 516.0
HFD2_k127_8069236_4 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 481.0
HFD2_k127_8069236_5 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006984 380.0
HFD2_k127_8069236_6 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000007958 198.0
HFD2_k127_8069236_7 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0000000000001538 82.0
HFD2_k127_8126744_0 PQQ-like domain K00114 - 1.1.2.8 7.261e-245 774.0
HFD2_k127_8126744_1 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 461.0
HFD2_k127_8126744_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 317.0
HFD2_k127_8126744_3 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000004018 257.0
HFD2_k127_8126744_4 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000001679 175.0
HFD2_k127_8126744_5 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000007882 175.0
HFD2_k127_8126744_6 ubiE/COQ5 methyltransferase family - - - 0.00000000000000007426 91.0
HFD2_k127_8126744_7 Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - 0.0000000000002775 83.0
HFD2_k127_8151641_0 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 332.0
HFD2_k127_8151641_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001318 261.0
HFD2_k127_8151641_2 Transposase proposed to express due to -1 translational frameshift at the sequence 5'-AAAAAC-3' - - - 0.000000000000000005738 87.0
HFD2_k127_8151641_3 RibD C-terminal domain - - - 0.00000000000000002212 81.0
HFD2_k127_8151641_4 Integrase - - - 0.0000002889 53.0
HFD2_k127_8151641_5 PFAM Phosphomethylpyrimidine kinase K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000003043 49.0
HFD2_k127_8169458_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1335.0
HFD2_k127_8169458_1 Periplasmic binding protein domain K01999 - - 4.224e-196 619.0
HFD2_k127_8169458_10 Belongs to the ATCase OTCase family K00608,K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 394.0
HFD2_k127_8169458_11 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 364.0
HFD2_k127_8169458_12 COGs COG0569 K transport systems NAD-binding component K03499,K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 362.0
HFD2_k127_8169458_13 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 356.0
HFD2_k127_8169458_14 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 357.0
HFD2_k127_8169458_15 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008 331.0
HFD2_k127_8169458_16 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008659 297.0
HFD2_k127_8169458_17 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 293.0
HFD2_k127_8169458_18 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000194 278.0
HFD2_k127_8169458_19 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003344 263.0
HFD2_k127_8169458_2 histidine kinase, HAMP K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 558.0
HFD2_k127_8169458_20 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000104 259.0
HFD2_k127_8169458_21 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000004307 256.0
HFD2_k127_8169458_22 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008353 251.0
HFD2_k127_8169458_23 PFAM formyl transferase domain protein K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000001223 237.0
HFD2_k127_8169458_24 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000002404 235.0
HFD2_k127_8169458_25 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000005513 237.0
HFD2_k127_8169458_26 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000002073 227.0
HFD2_k127_8169458_27 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000003853 227.0
HFD2_k127_8169458_28 TIGR00255 family - - - 0.000000000000000000000000000000000000000000000000000000000009893 218.0
HFD2_k127_8169458_29 hexokinase K00844 - 2.7.1.1 0.00000000000000000000000000000000000000000000000000000009778 212.0
HFD2_k127_8169458_3 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 535.0
HFD2_k127_8169458_30 Essential for recycling GMP and indirectly, cGMP K00942,K01591 GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8,4.1.1.23 0.0000000000000000000000000000000000000000000000000000004394 199.0
HFD2_k127_8169458_31 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000007772 211.0
HFD2_k127_8169458_32 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000009872 208.0
HFD2_k127_8169458_33 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000002075 181.0
HFD2_k127_8169458_34 orotidine-5'-phosphate decarboxylase activity K01591,K13421 GO:0000003,GO:0000909,GO:0002119,GO:0002164,GO:0003006,GO:0003674,GO:0003824,GO:0004588,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0006996,GO:0007033,GO:0007040,GO:0007275,GO:0007568,GO:0008150,GO:0008152,GO:0008340,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009314,GO:0009405,GO:0009411,GO:0009416,GO:0009628,GO:0009653,GO:0009790,GO:0009791,GO:0009792,GO:0009887,GO:0009987,GO:0010033,GO:0010165,GO:0010212,GO:0010225,GO:0010259,GO:0010332,GO:0014070,GO:0016043,GO:0016477,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0019860,GO:0019953,GO:0022414,GO:0022610,GO:0030447,GO:0030582,GO:0030584,GO:0031012,GO:0032501,GO:0032502,GO:0032504,GO:0034404,GO:0034641,GO:0034654,GO:0035239,GO:0035295,GO:0040007,GO:0040008,GO:0040011,GO:0040014,GO:0040018,GO:0042221,GO:0042455,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044182,GO:0044205,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0044706,GO:0045927,GO:0046049,GO:0046107,GO:0046108,GO:0046109,GO:0046112,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0048513,GO:0048518,GO:0048546,GO:0048557,GO:0048562,GO:0048565,GO:0048566,GO:0048568,GO:0048598,GO:0048608,GO:0048609,GO:0048638,GO:0048639,GO:0048731,GO:0048856,GO:0048870,GO:0050789,GO:0050793,GO:0050896,GO:0051094,GO:0051179,GO:0051239,GO:0051240,GO:0051674,GO:0051704,GO:0055086,GO:0055123,GO:0060378,GO:0061458,GO:0062039,GO:0062040,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0075259,GO:0080171,GO:0090407,GO:0090727,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.10,4.1.1.23 0.000000000000000000000000000000000000000000000004791 188.0
HFD2_k127_8169458_35 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000002873 178.0
HFD2_k127_8169458_36 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000001156 156.0
HFD2_k127_8169458_37 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0008463,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043021,GO:0043022,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000009689 154.0
HFD2_k127_8169458_38 MgtC family K07507 - - 0.00000000000000000000000000000000000009322 156.0
HFD2_k127_8169458_39 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000002867 131.0
HFD2_k127_8169458_4 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 534.0
HFD2_k127_8169458_40 Isochorismatase family - - - 0.0000000000000000000000004549 113.0
HFD2_k127_8169458_41 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000001805 104.0
HFD2_k127_8169458_42 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000003578 101.0
HFD2_k127_8169458_43 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000004171 91.0
HFD2_k127_8169458_44 KR domain K00059 - 1.1.1.100 0.000001693 57.0
HFD2_k127_8169458_45 Cupin - - - 0.000005314 57.0
HFD2_k127_8169458_46 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000009879 56.0
HFD2_k127_8169458_47 Domain of unknown function (DUF4390) - - - 0.00003424 53.0
HFD2_k127_8169458_48 Protein of unknown function (DUF1624) - - - 0.0001913 53.0
HFD2_k127_8169458_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 514.0
HFD2_k127_8169458_6 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 491.0
HFD2_k127_8169458_7 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 466.0
HFD2_k127_8169458_8 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 412.0
HFD2_k127_8169458_9 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007212 401.0
HFD2_k127_8173211_0 Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0 1277.0
HFD2_k127_8173211_1 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 479.0
HFD2_k127_8173211_2 AhpC/TSA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 343.0
HFD2_k127_8173211_3 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000003379 211.0
HFD2_k127_8173211_4 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000008821 96.0
HFD2_k127_8173211_5 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016020,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0052652,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.1 0.00000000000000003702 97.0
HFD2_k127_8229734_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007129 606.0
HFD2_k127_8229734_1 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 591.0
HFD2_k127_8229734_10 Flagellar Assembly Protein A K09749 - - 0.0000000000000000000000000000000000000000000000000000000000000000002526 249.0
HFD2_k127_8229734_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000002048 136.0
HFD2_k127_8229734_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000002462 69.0
HFD2_k127_8229734_13 Putative zinc-finger - - - 0.00000004525 64.0
HFD2_k127_8229734_14 RibD C-terminal domain K00082 - 1.1.1.193 0.0000002557 61.0
HFD2_k127_8229734_2 ATP dependent DNA ligase C terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 523.0
HFD2_k127_8229734_3 Domain of unknown function (DUF4331) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 508.0
HFD2_k127_8229734_4 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 440.0
HFD2_k127_8229734_5 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 421.0
HFD2_k127_8229734_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 338.0
HFD2_k127_8229734_7 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 316.0
HFD2_k127_8229734_8 ATPases associated with a variety of cellular activities K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000224 289.0
HFD2_k127_8229734_9 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003473 264.0
HFD2_k127_8363293_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.541e-297 921.0
HFD2_k127_8363293_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.898e-256 803.0
HFD2_k127_8363293_10 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 453.0
HFD2_k127_8363293_11 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 445.0
HFD2_k127_8363293_12 Associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 404.0
HFD2_k127_8363293_13 Dehydrogenase E1 component K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 409.0
HFD2_k127_8363293_14 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 372.0
HFD2_k127_8363293_15 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 368.0
HFD2_k127_8363293_16 Component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 342.0
HFD2_k127_8363293_17 Belongs to the dCTP deaminase family K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 312.0
HFD2_k127_8363293_18 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 290.0
HFD2_k127_8363293_19 Alpha/beta hydrolase family K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001093 286.0
HFD2_k127_8363293_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 3.654e-224 712.0
HFD2_k127_8363293_20 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006893 279.0
HFD2_k127_8363293_21 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008757 264.0
HFD2_k127_8363293_22 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000191 265.0
HFD2_k127_8363293_23 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003148 257.0
HFD2_k127_8363293_24 PFAM Haloacid dehalogenase domain protein hydrolase K01560,K07025 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000002411 246.0
HFD2_k127_8363293_25 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000001558 236.0
HFD2_k127_8363293_26 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000000000000000000007168 224.0
HFD2_k127_8363293_27 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000002774 208.0
HFD2_k127_8363293_28 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000008624 181.0
HFD2_k127_8363293_29 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.000000000000000000000000000000000000000005584 174.0
HFD2_k127_8363293_3 Hsp70 protein K04043,K04044 - - 2.176e-218 693.0
HFD2_k127_8363293_30 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000003952 177.0
HFD2_k127_8363293_31 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000004276 166.0
HFD2_k127_8363293_32 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.000000000000000000000000000000000000001626 152.0
HFD2_k127_8363293_33 Transcriptional regulator - - - 0.0000000000000000000000000000000001313 137.0
HFD2_k127_8363293_34 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000006064 128.0
HFD2_k127_8363293_35 Belongs to the HesB IscA family K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005515,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0097428,GO:1901564 - 0.00000000000000000000000000000007476 129.0
HFD2_k127_8363293_36 Thioredoxin-like - - - 0.00000000000000000000000000000463 131.0
HFD2_k127_8363293_37 DnaJ molecular chaperone homology domain K04082 - - 0.0000000000000000000000000009526 121.0
HFD2_k127_8363293_38 iron-sulfur cluster assembly - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.000000000000000000000000212 106.0
HFD2_k127_8363293_39 Glycosyl transferase family 41 K09667 GO:0000003,GO:0000123,GO:0000785,GO:0000791,GO:0001678,GO:0001932,GO:0001933,GO:0001934,GO:0002119,GO:0002164,GO:0002237,GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005488,GO:0005515,GO:0005543,GO:0005547,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0006040,GO:0006041,GO:0006047,GO:0006048,GO:0006073,GO:0006091,GO:0006109,GO:0006110,GO:0006111,GO:0006112,GO:0006139,GO:0006140,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006470,GO:0006473,GO:0006475,GO:0006479,GO:0006486,GO:0006493,GO:0006508,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007444,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0007626,GO:0008080,GO:0008134,GO:0008150,GO:0008152,GO:0008194,GO:0008213,GO:0008219,GO:0008289,GO:0008361,GO:0008375,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009791,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010646,GO:0010675,GO:0010799,GO:0010801,GO:0010876,GO:0010906,GO:0010941,GO:0012501,GO:0012505,GO:0015980,GO:0016020,GO:0016043,GO:0016262,GO:0016311,GO:0016407,GO:0016410,GO:0016485,GO:0016569,GO:0016570,GO:0016571,GO:0016573,GO:0016579,GO:0016740,GO:0016746,GO:0016747,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0018022,GO:0018023,GO:0018130,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019725,GO:0019904,GO:0019915,GO:0022607,GO:0023051,GO:0023052,GO:0030141,GO:0030162,GO:0030246,GO:0030808,GO:0030811,GO:0030900,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031248,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031401,GO:0031410,GO:0031667,GO:0031974,GO:0031981,GO:0031982,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032387,GO:0032434,GO:0032435,GO:0032496,GO:0032501,GO:0032502,GO:0032535,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032922,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033135,GO:0033137,GO:0033157,GO:0033218,GO:0033500,GO:0033993,GO:0034284,GO:0034641,GO:0034645,GO:0034654,GO:0034968,GO:0035020,GO:0035091,GO:0035220,GO:0035295,GO:0035556,GO:0036094,GO:0036211,GO:0036477,GO:0040024,GO:0042176,GO:0042177,GO:0042221,GO:0042277,GO:0042325,GO:0042326,GO:0042327,GO:0042578,GO:0042588,GO:0042592,GO:0042593,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043255,GO:0043412,GO:0043413,GO:0043414,GO:0043434,GO:0043467,GO:0043470,GO:0043543,GO:0043933,GO:0043967,GO:0043981,GO:0043982,GO:0043984,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045475,GO:0045793,GO:0045861,GO:0045862,GO:0045893,GO:0045935,GO:0045936,GO:0045937,GO:0045944,GO:0046349,GO:0046483,GO:0046578,GO:0046626,GO:0048015,GO:0048017,GO:0048029,GO:0048311,GO:0048312,GO:0048471,GO:0048511,GO:0048512,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051056,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051196,GO:0051223,GO:0051224,GO:0051235,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051276,GO:0051291,GO:0051568,GO:0051604,GO:0051640,GO:0051641,GO:0051646,GO:0051704,GO:0051707,GO:0051716,GO:0055082,GO:0055086,GO:0055114,GO:0060255,GO:0060322,GO:0060341,GO:0060429,GO:0060548,GO:0061085,GO:0061087,GO:0061136,GO:0062012,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0070201,GO:0070206,GO:0070207,GO:0070208,GO:0070646,GO:0070647,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071375,GO:0071396,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0080182,GO:0090066,GO:0090087,GO:0090313,GO:0090315,GO:0090317,GO:0097237,GO:0097363,GO:0097458,GO:0097708,GO:0099503,GO:0120025,GO:0140096,GO:1900037,GO:1900038,GO:1900076,GO:1900180,GO:1900182,GO:1900371,GO:1900542,GO:1901071,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901799,GO:1901981,GO:1902275,GO:1902493,GO:1902494,GO:1902531,GO:1902680,GO:1903050,GO:1903051,GO:1903320,GO:1903321,GO:1903362,GO:1903363,GO:1903426,GO:1903428,GO:1903506,GO:1903508,GO:1903533,GO:1903578,GO:1903827,GO:1903828,GO:1903829,GO:1904950,GO:1905269,GO:1905475,GO:1905476,GO:1990234,GO:2000058,GO:2000059,GO:2000112,GO:2000377,GO:2000379,GO:2001141,GO:2001169,GO:2001252 2.4.1.255 0.0000000000000002043 92.0
HFD2_k127_8363293_4 PFAM glycosyl transferase family 35 K00688 - 2.4.1.1 3.499e-194 624.0
HFD2_k127_8363293_40 - - - - 0.00000000000001017 76.0
HFD2_k127_8363293_42 Pup-like protein K13570 - - 0.0000000000004944 78.0
HFD2_k127_8363293_43 Putative zinc-finger - - - 0.00000000004691 66.0
HFD2_k127_8363293_44 regulatory protein, FmdB family - - - 0.0000000006251 62.0
HFD2_k127_8363293_45 - - - - 0.00000001609 67.0
HFD2_k127_8363293_5 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 557.0
HFD2_k127_8363293_6 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 501.0
HFD2_k127_8363293_7 PFAM Pyridine nucleotide-disulphide oxidoreductase, FAD NAD(P)-binding domain, pyridine nucleotide-disulfide oxidoreductase dimerization region, FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007679 509.0
HFD2_k127_8363293_8 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 540.0
HFD2_k127_8363293_9 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 461.0
HFD2_k127_8379452_0 acyl-CoA dehydrogenase activity K00248,K00253 - 1.3.8.1,1.3.8.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 373.0
HFD2_k127_8379452_1 dehydratase - - - 0.000000000000000000000000000000000000000000000001108 198.0
HFD2_k127_8379452_2 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000005205 175.0
HFD2_k127_8379452_3 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 - 0.0000000000000296 78.0
HFD2_k127_8524309_0 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 608.0
HFD2_k127_8524309_1 Deoxyribodipyrimidine photo-lyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 609.0
HFD2_k127_8524309_10 Belongs to the peptidase S14 family K01358 - 3.4.21.92 0.000000000000000000000000000000001772 142.0
HFD2_k127_8524309_11 Peptidase, M23 - - - 0.0000000000000000000000000000001156 134.0
HFD2_k127_8524309_2 Potassium uptake protein K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 459.0
HFD2_k127_8524309_3 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 406.0
HFD2_k127_8524309_4 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 353.0
HFD2_k127_8524309_5 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000000000000000000000000000000000000000000000000000004402 243.0
HFD2_k127_8524309_6 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000001634 194.0
HFD2_k127_8524309_7 Domain of unknown function (DUF3597) - - - 0.0000000000000000000000000000000000000000000004624 180.0
HFD2_k127_8524309_8 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000003912 145.0
HFD2_k127_8524309_9 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000003547 137.0
HFD2_k127_8601957_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1151.0
HFD2_k127_8601957_1 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 560.0
HFD2_k127_8601957_10 CO dehydrogenase flavoprotein C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008209 285.0
HFD2_k127_8601957_11 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000001839 240.0
HFD2_k127_8601957_13 PAC2 family - - - 0.00000000000000000000000000000000000000000000000001342 191.0
HFD2_k127_8601957_14 EVE domain - - - 0.0000000000000000000000000000000000000000003202 162.0
HFD2_k127_8601957_15 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.00000000000000000000000000000000000000008025 174.0
HFD2_k127_8601957_16 Belongs to the mandelate racemase muconate lactonizing enzyme family K01684 - 4.2.1.6 0.00000000000000000000000000000002951 129.0
HFD2_k127_8601957_17 phosphatidate phosphatase activity - - - 0.00000000000000002647 93.0
HFD2_k127_8601957_18 acetyltransferase K00661 - 2.3.1.79 0.00000000000000003643 89.0
HFD2_k127_8601957_19 - - - - 0.000000000000002098 86.0
HFD2_k127_8601957_2 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 503.0
HFD2_k127_8601957_20 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.000000000000004659 87.0
HFD2_k127_8601957_21 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000124 86.0
HFD2_k127_8601957_22 Sulfatase K01130 - 3.1.6.1 0.0000000000001017 76.0
HFD2_k127_8601957_23 HPr kinase - - - 0.0000000007808 70.0
HFD2_k127_8601957_24 dehydratase - - - 0.000000002022 68.0
HFD2_k127_8601957_25 Uncharacterised nucleotidyltransferase - - - 0.000000006119 68.0
HFD2_k127_8601957_26 protein localization to T-tubule K10380,K15502 - - 0.0003474 51.0
HFD2_k127_8601957_27 Protein tyrosine kinase - - - 0.0006157 51.0
HFD2_k127_8601957_28 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000955 49.0
HFD2_k127_8601957_3 acyl-CoA transferases carnitine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 448.0
HFD2_k127_8601957_4 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 448.0
HFD2_k127_8601957_5 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 413.0
HFD2_k127_8601957_6 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009112 354.0
HFD2_k127_8601957_7 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 353.0
HFD2_k127_8601957_8 Thiamine pyrophosphate enzyme, central domain K01576 - 4.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 325.0
HFD2_k127_8601957_9 PFAM PKD domain containing protein K11751 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 310.0
HFD2_k127_8617783_0 Glycosyl transferases group 1 K19424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 419.0
HFD2_k127_8617783_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000238 243.0
HFD2_k127_8617783_2 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000122 237.0
HFD2_k127_8617783_3 glycosyl transferase group 1 - - - 0.00000008049 58.0
HFD2_k127_8685419_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1357.0
HFD2_k127_8685419_1 Amidohydrolase family K01464 - 3.5.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 433.0
HFD2_k127_8685419_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 321.0
HFD2_k127_8685419_3 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000001982 214.0
HFD2_k127_8685419_4 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000003683 220.0
HFD2_k127_8685419_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000001914 209.0
HFD2_k127_8685419_6 Transcription elongation factor, N-terminal K03624 - - 0.0000000000000000000000000000000000000000008795 171.0
HFD2_k127_8685419_7 DNA-sulfur modification-associated - - - 0.00000000000000000004189 103.0
HFD2_k127_8685419_8 TIGRFAM ABC-2 type transporter, NodJ family K09694 - - 0.0000000000000000002648 95.0
HFD2_k127_8685419_9 Haem-degrading - - - 0.0000001392 59.0
HFD2_k127_914341_0 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 591.0
HFD2_k127_914341_1 Protoporphyrinogen oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 571.0
HFD2_k127_914341_10 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000001256 248.0
HFD2_k127_914341_11 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000002704 220.0
HFD2_k127_914341_12 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000003619 203.0
HFD2_k127_914341_13 Protein of unknown function (DUF2868) - - - 0.0000000000000000000000000000000000000000000000000004442 212.0
HFD2_k127_914341_14 phosphorelay signal transduction system K11443 - - 0.0000000000000000000000000000000001048 136.0
HFD2_k127_914341_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000001244 134.0
HFD2_k127_914341_16 Glycosyltransferase like family 2 - - - 0.00000000000000000000000001125 121.0
HFD2_k127_914341_17 Glycosyltransferase K21001 - - 0.000000000000000000009765 107.0
HFD2_k127_914341_18 - - - - 0.00000000000000000006135 105.0
HFD2_k127_914341_2 3-isopropylmalate dehydrogenase activity K00030,K00052 - 1.1.1.41,1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 510.0
HFD2_k127_914341_20 polysaccharide biosynthetic process - - - 0.0000000000001914 84.0
HFD2_k127_914341_21 AntiSigma factor - - - 0.000005875 58.0
HFD2_k127_914341_22 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000009528 58.0
HFD2_k127_914341_23 nitrous oxide K19341 - - 0.00002852 48.0
HFD2_k127_914341_24 Flavin containing amine oxidoreductase - - - 0.00004279 51.0
HFD2_k127_914341_3 5'-nucleotidase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 494.0
HFD2_k127_914341_4 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 458.0
HFD2_k127_914341_5 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005713 451.0
HFD2_k127_914341_6 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007852 380.0
HFD2_k127_914341_7 Domain of unknown function (DUF3482) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009857 363.0
HFD2_k127_914341_8 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 331.0
HFD2_k127_914341_9 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001709 259.0
HFD2_k127_921877_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007047 581.0
HFD2_k127_921877_1 Phytanoyl-CoA dioxygenase (PhyH) K10674 - 1.14.11.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 461.0
HFD2_k127_921877_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 434.0
HFD2_k127_921877_3 PFAM L-carnitine dehydratase bile acid-inducible protein F K07544,K07749 - 2.8.3.15,2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 394.0
HFD2_k127_921877_4 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001671 273.0
HFD2_k127_921877_5 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000002953 200.0
HFD2_k127_921877_6 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000001441 164.0
HFD2_k127_921877_7 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000000000282 151.0
HFD2_k127_921877_8 Histidine kinase - - - 0.0000000000000000000001208 106.0
HFD2_k127_921877_9 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000002173 73.0
HFD2_k127_9419_0 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 1.305e-196 626.0
HFD2_k127_951756_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 424.0
HFD2_k127_951756_1 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001566 259.0
HFD2_k127_980268_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.812e-247 777.0
HFD2_k127_980268_1 NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008291 487.0
HFD2_k127_980268_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.00000000000000000000000000000000004713 142.0
HFD2_k127_980268_11 Ribbon-helix-helix domain - - - 0.00000000000000000000000007932 111.0
HFD2_k127_980268_12 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000001293 97.0
HFD2_k127_980268_13 Trm112p-like protein K09791 - - 0.0000000004351 71.0
HFD2_k127_980268_14 Archease protein family (MTH1598/TM1083) - GO:0000394,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0007275,GO:0007399,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0010720,GO:0010975,GO:0010976,GO:0016070,GO:0022008,GO:0030154,GO:0031344,GO:0031346,GO:0031974,GO:0031981,GO:0032101,GO:0032103,GO:0032501,GO:0032502,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0046483,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0048679,GO:0048680,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050769,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051128,GO:0051130,GO:0051239,GO:0051240,GO:0051960,GO:0051962,GO:0060284,GO:0065007,GO:0070013,GO:0070570,GO:0070572,GO:0071704,GO:0072669,GO:0080134,GO:0080135,GO:0090304,GO:0120035,GO:1901360,GO:1903034,GO:1903036,GO:2000026 - 0.0002115 53.0
HFD2_k127_980268_2 DnaJ central domain K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 409.0
HFD2_k127_980268_3 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 295.0
HFD2_k127_980268_4 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001317 286.0
HFD2_k127_980268_5 HrcA protein C terminal domain K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000001631 242.0
HFD2_k127_980268_6 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000627 228.0
HFD2_k127_980268_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000003505 174.0
HFD2_k127_980268_8 repeat protein - - - 0.000000000000000000000000000000000000001402 156.0
HFD2_k127_980268_9 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000106 153.0
HFD2_k127_981543_0 Extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 422.0
HFD2_k127_981543_1 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 345.0
HFD2_k127_981543_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 333.0
HFD2_k127_981543_3 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 301.0
HFD2_k127_981543_4 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000009147 212.0
HFD2_k127_981543_5 Family 5 K02035 - - 0.00000000000000000000000000000001596 140.0
HFD2_k127_981543_6 COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family - - - 0.00000000000000000000002246 117.0
HFD2_k127_981543_7 Winged helix-turn-helix DNA-binding - - - 0.000000004753 60.0
HFD2_k127_998165_0 oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor K00311 GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204 1.5.5.1 1.601e-213 676.0
HFD2_k127_998165_1 Electron transfer flavoprotein domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004267 267.0
HFD2_k127_998165_2 pathogenesis - - - 0.000000002905 64.0